LOCUS       DAVKBC010000001       137097 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVKBC010000001 DAVKBC010000000
VERSION     DAVKBC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 137097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 137097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..137097
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.001"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            416..1510
                     /locus_tag="VWX64_000001"
                     /pseudo
     CDS             416..1510
                     /locus_tag="VWX64_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            1729..3075
                     /locus_tag="VWX64_000002"
     CDS             1729..3075
                     /locus_tag="VWX64_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEU9189579.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     QISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            complement(3879..4907)
                     /gene="queA"
                     /locus_tag="VWX64_000003"
     CDS             complement(3879..4907)
                     /gene="queA"
                     /locus_tag="VWX64_000003"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU9189580.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            5058..5765
                     /locus_tag="VWX64_000004"
     CDS             5058..5765
                     /locus_tag="VWX64_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU9189581.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            5905..6081
                     /locus_tag="VWX64_000005"
     CDS             5905..6081
                     /locus_tag="VWX64_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU9189582.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            6211..7146
                     /locus_tag="VWX64_000006"
     CDS             6211..7146
                     /locus_tag="VWX64_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU9189583.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            7139..7927
                     /locus_tag="VWX64_000007"
     CDS             7139..7927
                     /locus_tag="VWX64_000007"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU9189584.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            7928..8311
                     /locus_tag="VWX64_000008"
     CDS             7928..8311
                     /locus_tag="VWX64_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU9189585.1"
                     /translation="MLEVAYILVALAVIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            8327..8716
                     /locus_tag="VWX64_000009"
     CDS             8327..8716
                     /locus_tag="VWX64_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU9189586.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            8800..9930
                     /locus_tag="VWX64_000010"
     CDS             8800..9930
                     /locus_tag="VWX64_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU9189587.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            9935..10672
                     /locus_tag="VWX64_000011"
     CDS             9935..10672
                     /locus_tag="VWX64_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU9189588.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            10683..11456
                     /locus_tag="VWX64_000012"
     CDS             10683..11456
                     /locus_tag="VWX64_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU9189589.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            11446..12063
                     /locus_tag="VWX64_000013"
     CDS             11446..12063
                     /locus_tag="VWX64_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU9189590.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            12273..12674
                     /locus_tag="VWX64_000014"
     CDS             12273..12674
                     /locus_tag="VWX64_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU9189591.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            12674..12952
                     /locus_tag="VWX64_000015"
     CDS             12674..12952
                     /locus_tag="VWX64_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU9189592.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            12942..13715
                     /locus_tag="VWX64_000016"
     CDS             12942..13715
                     /locus_tag="VWX64_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU9189593.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            13716..15020
                     /locus_tag="VWX64_000017"
     CDS             13716..15020
                     /locus_tag="VWX64_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU9189594.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKKPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLQETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            15594..16472
                     /gene="pstS"
                     /locus_tag="VWX64_000018"
     CDS             15594..16472
                     /gene="pstS"
                     /locus_tag="VWX64_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU9189595.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            16472..17389
                     /gene="pstC"
                     /locus_tag="VWX64_000019"
     CDS             16472..17389
                     /gene="pstC"
                     /locus_tag="VWX64_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9189596.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            17379..18263
                     /gene="pstA"
                     /locus_tag="VWX64_000020"
     CDS             17379..18263
                     /gene="pstA"
                     /locus_tag="VWX64_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9189597.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            18274..19077
                     /gene="pstB"
                     /locus_tag="VWX64_000021"
     CDS             18274..19077
                     /gene="pstB"
                     /locus_tag="VWX64_000021"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9189598.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLSQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            19090..19848
                     /gene="pstB"
                     /locus_tag="VWX64_000022"
     CDS             19090..19848
                     /gene="pstB"
                     /locus_tag="VWX64_000022"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9189599.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            19860..20513
                     /gene="phoU"
                     /locus_tag="VWX64_000023"
     CDS             19860..20513
                     /gene="phoU"
                     /locus_tag="VWX64_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9189600.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            20670..21485
                     /locus_tag="VWX64_000024"
     CDS             20670..21485
                     /locus_tag="VWX64_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9189601.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTNLKSANIAAQKGT
                     VPESMVKEQLPKVQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(21505..22776)
                     /locus_tag="VWX64_000025"
     CDS             complement(21505..22776)
                     /locus_tag="VWX64_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU9189602.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKLSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            22918..23649
                     /gene="budA"
                     /locus_tag="VWX64_000026"
     CDS             22918..23649
                     /gene="budA"
                     /locus_tag="VWX64_000026"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU9189603.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            23659..24416
                     /locus_tag="VWX64_000027"
                     /pseudo
     CDS             23659..24416
                     /locus_tag="VWX64_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            24528..25478
                     /gene="murB"
                     /locus_tag="VWX64_000028"
     CDS             24528..25478
                     /gene="murB"
                     /locus_tag="VWX64_000028"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU9189604.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            25537..26694
                     /locus_tag="VWX64_000029"
     CDS             25537..26694
                     /locus_tag="VWX64_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189605.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            26675..27481
                     /locus_tag="VWX64_000030"
     CDS             26675..27481
                     /locus_tag="VWX64_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9189606.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            27478..28251
                     /locus_tag="VWX64_000031"
     CDS             27478..28251
                     /locus_tag="VWX64_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9189607.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            28248..29318
                     /locus_tag="VWX64_000032"
     CDS             28248..29318
                     /locus_tag="VWX64_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9189608.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKELQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKKLLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            29571..29810
                     /locus_tag="VWX64_000033"
     CDS             29571..29810
                     /locus_tag="VWX64_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189609.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            30085..30570
                     /locus_tag="VWX64_000034"
     CDS             30085..30570
                     /locus_tag="VWX64_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU9189610.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEILESQS
                     H"
     gene            30592..33210
                     /gene="alaS"
                     /locus_tag="VWX64_000035"
     CDS             30592..33210
                     /gene="alaS"
                     /locus_tag="VWX64_000035"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU9189611.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESAFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELALIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(33300..34754)
                     /locus_tag="VWX64_000036"
     CDS             complement(33300..34754)
                     /locus_tag="VWX64_000036"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU9189612.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAEDAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHMEAFQVIEVDPVDRTVKLGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKSVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            34934..35683
                     /locus_tag="VWX64_000037"
     CDS             34934..35683
                     /locus_tag="VWX64_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189613.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSSSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            35664..36776
                     /locus_tag="VWX64_000038"
     CDS             35664..36776
                     /locus_tag="VWX64_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189614.1"
                     /translation="MRLKVIKKLVDINILYSSKEANLANLRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFVVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPFFYSSLYSSCQ"
     gene            36748..37308
                     /locus_tag="VWX64_000039"
     CDS             36748..37308
                     /locus_tag="VWX64_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189615.1"
                     /translation="MALFIAVVNNNITSLPSIALSLERENVDFLKSLPFDFARYVKVK
                     FWIIFAVQSFLPVLTLLGLSLYLGLPILSMIYLIVAWILASVILSCHHYFKDVKNLST
                     NWSSITDLVNRSNGIVAIVLLFILLFIYSAILMALVIGSIFLVQSLSPILAISLGVGA
                     LILLLALAIFGYHYYLSRILAEIEKR"
     gene            37995..39158
                     /locus_tag="VWX64_000040"
     CDS             37995..39158
                     /locus_tag="VWX64_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU9189616.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            39155..39832
                     /locus_tag="VWX64_000041"
     CDS             39155..39832
                     /locus_tag="VWX64_000041"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU9189617.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            39822..40676
                     /locus_tag="VWX64_000042"
     CDS             39822..40676
                     /locus_tag="VWX64_000042"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU9189618.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQFSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            40695..41762
                     /locus_tag="VWX64_000043"
     CDS             40695..41762
                     /locus_tag="VWX64_000043"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU9189619.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            41772..42938
                     /gene="aroC"
                     /locus_tag="VWX64_000044"
     CDS             41772..42938
                     /gene="aroC"
                     /locus_tag="VWX64_000044"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU9189620.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMYVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            42948..44051
                     /locus_tag="VWX64_000045"
     CDS             42948..44051
                     /locus_tag="VWX64_000045"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU9189621.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            44062..44400
                     /locus_tag="VWX64_000046"
     CDS             44062..44400
                     /locus_tag="VWX64_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU9189622.1"
                     /translation="MSNIYDSANDLSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            44492..45775
                     /gene="aroA"
                     /locus_tag="VWX64_000047"
     CDS             44492..45775
                     /gene="aroA"
                     /locus_tag="VWX64_000047"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU9189623.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITVQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            45768..46244
                     /locus_tag="VWX64_000048"
     CDS             45768..46244
                     /locus_tag="VWX64_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU9189624.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQRDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            46241..47089
                     /gene="pheA"
                     /locus_tag="VWX64_000049"
     CDS             46241..47089
                     /gene="pheA"
                     /locus_tag="VWX64_000049"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9189625.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            47086..48360
                     /gene="psr"
                     /locus_tag="VWX64_000050"
     CDS             47086..48360
                     /gene="psr"
                     /locus_tag="VWX64_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU9189626.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFVYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            48639..49484
                     /locus_tag="VWX64_000051"
     CDS             48639..49484
                     /locus_tag="VWX64_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9189627.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            49474..50577
                     /locus_tag="VWX64_000052"
     CDS             49474..50577
                     /locus_tag="VWX64_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9189628.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            50579..51565
                     /locus_tag="VWX64_000053"
     CDS             50579..51565
                     /locus_tag="VWX64_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9189629.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            51581..53014
                     /locus_tag="VWX64_000054"
     CDS             51581..53014
                     /locus_tag="VWX64_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU9189630.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMI
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            53043..54077
                     /locus_tag="VWX64_000055"
     CDS             53043..54077
                     /locus_tag="VWX64_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9189631.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            54277..55014
                     /gene="mecA"
                     /locus_tag="VWX64_000056"
     CDS             54277..55014
                     /gene="mecA"
                     /locus_tag="VWX64_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU9189632.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            55165..56451
                     /locus_tag="VWX64_000057"
     CDS             55165..56451
                     /locus_tag="VWX64_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU9189633.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVAFYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            56453..57322
                     /locus_tag="VWX64_000058"
     CDS             56453..57322
                     /locus_tag="VWX64_000058"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU9189634.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            57572..58510
                     /gene="msrB"
                     /locus_tag="VWX64_000059"
     CDS             57572..58510
                     /gene="msrB"
                     /locus_tag="VWX64_000059"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9189635.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            58568..60292
                     /locus_tag="VWX64_000060"
     CDS             58568..60292
                     /locus_tag="VWX64_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189636.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLIPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVKLFKGTIRSNLTLGLNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            60294..62042
                     /locus_tag="VWX64_000061"
     CDS             60294..62042
                     /locus_tag="VWX64_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189637.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQFPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            62299..63558
                     /locus_tag="VWX64_000062"
     CDS             62299..63558
                     /locus_tag="VWX64_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU9189638.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIELLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVVVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    63634..63769
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            63808..64308
                     /locus_tag="VWX64_000063"
     CDS             63808..64308
                     /locus_tag="VWX64_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU9189639.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            64384..64752
                     /gene="rplL"
                     /locus_tag="VWX64_000064"
     CDS             64384..64752
                     /gene="rplL"
                     /locus_tag="VWX64_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU9189640.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            64939..65109
                     /locus_tag="VWX64_000065"
     CDS             64939..65109
                     /locus_tag="VWX64_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189641.1"
                     /translation="MQKEGQSSRQFMKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            65109..65357
                     /locus_tag="VWX64_000066"
                     /pseudo
     CDS             65109..65357
                     /locus_tag="VWX64_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            65371..65694
                     /locus_tag="VWX64_000067"
     CDS             65371..65694
                     /locus_tag="VWX64_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189642.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLW
                     EVSYD"
     gene            65687..66067
                     /locus_tag="VWX64_000068"
     CDS             65687..66067
                     /locus_tag="VWX64_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189643.1"
                     /translation="MIDLYLSKNSRRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLKLTDFIEMILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            66080..66313
                     /locus_tag="VWX64_000069"
     CDS             66080..66313
                     /locus_tag="VWX64_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU9189644.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            66316..66903
                     /locus_tag="VWX64_000070"
     CDS             66316..66903
                     /locus_tag="VWX64_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9189645.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYCASLIS
                     FLWMYAQRKQAHKVNMKSRIKWIGIGLASLLIISLCFSLIHAQESTNQANLIGLQYQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            67105..67242
                     /locus_tag="VWX64_000071"
                     /pseudo
     CDS             67105..67242
                     /locus_tag="VWX64_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
     gene            68036..68323
                     /locus_tag="VWX64_000072"
     CDS             68036..68323
                     /locus_tag="VWX64_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189646.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIFDGKAVEVTLREPYSRDILQVVKSIKQRQKLIAYRYKEGKLLFVKKEV"
     gene            68325..68468
                     /locus_tag="VWX64_000073"
     CDS             68325..68468
                     /locus_tag="VWX64_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000093669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189647.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKGLLKILEWSRCQALEQDSAYK
                     IGV"
     gene            68481..68777
                     /locus_tag="VWX64_000074"
     CDS             68481..68777
                     /locus_tag="VWX64_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000941983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189648.1"
                     /translation="MLQSPYAIDTINLKKDFLEKPIDIEKFKAFLEKEEIPLAIAWQG
                     DSLHFYTKDRSILDNHLDHLLEKMVNDPEKLSDFSMDKSLDDTIDEAKSQITFK"
     gene            complement(69011..70057)
                     /locus_tag="VWX64_000075"
                     /pseudo
     CDS             complement(69011..70057)
                     /locus_tag="VWX64_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(70594..72321)
                     /gene="ezrA"
                     /locus_tag="VWX64_000076"
     CDS             complement(70594..72321)
                     /gene="ezrA"
                     /locus_tag="VWX64_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU9189649.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHASDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(72403..74349)
                     /gene="gyrB"
                     /locus_tag="VWX64_000077"
     CDS             complement(72403..74349)
                     /gene="gyrB"
                     /locus_tag="VWX64_000077"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU9189650.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAE
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLAAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(74364..74927)
                     /locus_tag="VWX64_000078"
     CDS             complement(74364..74927)
                     /locus_tag="VWX64_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9189651.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNQGGRHFLVS
                     HRNDQVLEILEKPSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(75012..75566)
                     /locus_tag="VWX64_000079"
     CDS             complement(75012..75566)
                     /locus_tag="VWX64_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU9189652.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(75577..76800)
                     /locus_tag="VWX64_000080"
     CDS             complement(75577..76800)
                     /locus_tag="VWX64_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9189653.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(76837..79287)
                     /locus_tag="VWX64_000081"
     CDS             complement(76837..79287)
                     /locus_tag="VWX64_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU9189654.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SHSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(79487..80416)
                     /locus_tag="VWX64_000082"
     CDS             complement(79487..80416)
                     /locus_tag="VWX64_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9189655.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            80556..80843
                     /locus_tag="VWX64_000083"
     CDS             80556..80843
                     /locus_tag="VWX64_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU9189656.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(80877..82211)
                     /gene="ciaH"
                     /locus_tag="VWX64_000084"
     CDS             complement(80877..82211)
                     /gene="ciaH"
                     /locus_tag="VWX64_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU9189657.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(82201..82875)
                     /gene="ciaR"
                     /locus_tag="VWX64_000085"
     CDS             complement(82201..82875)
                     /gene="ciaR"
                     /locus_tag="VWX64_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU9189658.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(82984..85530)
                     /locus_tag="VWX64_000086"
     CDS             complement(82984..85530)
                     /locus_tag="VWX64_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU9189659.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(85653..86093)
                     /locus_tag="VWX64_000087"
     CDS             complement(85653..86093)
                     /locus_tag="VWX64_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU9189660.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(86068..86937)
                     /locus_tag="VWX64_000088"
     CDS             complement(86068..86937)
                     /locus_tag="VWX64_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU9189661.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDDDQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(86979..87707)
                     /locus_tag="VWX64_000089"
     CDS             complement(86979..87707)
                     /locus_tag="VWX64_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9189662.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(87715..88194)
                     /locus_tag="VWX64_000090"
     CDS             complement(87715..88194)
                     /locus_tag="VWX64_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9189663.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(88205..88903)
                     /locus_tag="VWX64_000091"
     CDS             complement(88205..88903)
                     /locus_tag="VWX64_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU9189664.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(88896..89162)
                     /locus_tag="VWX64_000092"
     CDS             complement(88896..89162)
                     /locus_tag="VWX64_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU9189665.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(89228..90154)
                     /locus_tag="VWX64_000093"
     CDS             complement(89228..90154)
                     /locus_tag="VWX64_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU9189666.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(90229..91044)
                     /locus_tag="VWX64_000094"
     CDS             complement(90229..91044)
                     /locus_tag="VWX64_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189667.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(91048..91368)
                     /locus_tag="VWX64_000095"
     CDS             complement(91048..91368)
                     /locus_tag="VWX64_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9189668.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(91789..93786)
                     /gene="metG"
                     /locus_tag="VWX64_000096"
     CDS             complement(91789..93786)
                     /gene="metG"
                     /locus_tag="VWX64_000096"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU9189669.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEKSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(93910..95169)
                     /locus_tag="VWX64_000097"
     CDS             complement(93910..95169)
                     /locus_tag="VWX64_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9189670.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENTNLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(95171..95872)
                     /locus_tag="VWX64_000098"
     CDS             complement(95171..95872)
                     /locus_tag="VWX64_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189671.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELIERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(95856..97055)
                     /locus_tag="VWX64_000099"
     CDS             complement(95856..97055)
                     /locus_tag="VWX64_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU9189672.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            97341..98687
                     /gene="gor"
                     /locus_tag="VWX64_000100"
     CDS             97341..98687
                     /gene="gor"
                     /locus_tag="VWX64_000100"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU9189673.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            98884..99420
                     /locus_tag="VWX64_000101"
     CDS             98884..99420
                     /locus_tag="VWX64_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU9189674.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAILSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGIAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            99471..99557
                     /locus_tag="VWX64_000102"
                     /pseudo
     CDS             99471..99557
                     /locus_tag="VWX64_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(99626..99841)
                     /locus_tag="VWX64_000103"
     CDS             complement(99626..99841)
                     /locus_tag="VWX64_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU9189675.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            99939..100259
                     /locus_tag="VWX64_000104"
     CDS             99939..100259
                     /locus_tag="VWX64_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189676.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(100289..100627)
                     /locus_tag="VWX64_000105"
     CDS             complement(100289..100627)
                     /locus_tag="VWX64_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189677.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(100639..101358)
                     /gene="trmD"
                     /locus_tag="VWX64_000106"
     CDS             complement(100639..101358)
                     /gene="trmD"
                     /locus_tag="VWX64_000106"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU9189678.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFNSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(101348..101866)
                     /gene="rimM"
                     /locus_tag="VWX64_000107"
     CDS             complement(101348..101866)
                     /gene="rimM"
                     /locus_tag="VWX64_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU9189679.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(101897..102685)
                     /locus_tag="VWX64_000108"
     CDS             complement(101897..102685)
                     /locus_tag="VWX64_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9189680.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(102789..103032)
                     /locus_tag="VWX64_000109"
                     /pseudo
     CDS             complement(102789..103032)
                     /locus_tag="VWX64_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            complement(103262..103501)
                     /locus_tag="VWX64_000110"
     CDS             complement(103262..103501)
                     /locus_tag="VWX64_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU9189681.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(103521..103793)
                     /gene="rpsP"
                     /locus_tag="VWX64_000111"
     CDS             complement(103521..103793)
                     /gene="rpsP"
                     /locus_tag="VWX64_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU9189682.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            103972..104172
                     /locus_tag="VWX64_000112"
     CDS             103972..104172
                     /locus_tag="VWX64_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189683.1"
                     /translation="MNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMNLLAD
                     DSLAGDIILLWRIQFGTFTTET"
     gene            104651..104872
                     /locus_tag="VWX64_000113"
     CDS             104651..104872
                     /locus_tag="VWX64_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189684.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            104955..105758
                     /locus_tag="VWX64_000114"
     CDS             104955..105758
                     /locus_tag="VWX64_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU9189685.1"
                     /translation="MKKLATLLLLSTVALAGCSNVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILNTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(105814..107355)
                     /locus_tag="VWX64_000115"
     CDS             complement(105814..107355)
                     /locus_tag="VWX64_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9189686.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHDPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(107357..107839)
                     /locus_tag="VWX64_000116"
     CDS             complement(107357..107839)
                     /locus_tag="VWX64_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9189687.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFSNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLSWLLYKRLHKNKIRN
                     "
     gene            complement(107839..108924)
                     /gene="rlmN"
                     /locus_tag="VWX64_000117"
     CDS             complement(107839..108924)
                     /gene="rlmN"
                     /locus_tag="VWX64_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU9189688.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIEIVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVNHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLRFNTMKRDRQKVVAAVNP"
     gene            complement(108945..109475)
                     /locus_tag="VWX64_000118"
     CDS             complement(108945..109475)
                     /locus_tag="VWX64_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU9189689.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(109632..110237)
                     /locus_tag="VWX64_000119"
     CDS             complement(109632..110237)
                     /locus_tag="VWX64_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU9189690.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(110410..111447)
                     /locus_tag="VWX64_000120"
     CDS             complement(110410..111447)
                     /locus_tag="VWX64_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU9189691.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(111481..112416)
                     /locus_tag="VWX64_000121"
     CDS             complement(111481..112416)
                     /locus_tag="VWX64_000121"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU9189692.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(112969..114159)
                     /locus_tag="VWX64_000122"
     CDS             complement(112969..114159)
                     /locus_tag="VWX64_000122"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU9189693.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTISEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLIRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(114374..115717)
                     /locus_tag="VWX64_000123"
     CDS             complement(114374..115717)
                     /locus_tag="VWX64_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9189694.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(115857..116672)
                     /locus_tag="VWX64_000124"
     CDS             complement(115857..116672)
                     /locus_tag="VWX64_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9189695.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(116724..118904)
                     /locus_tag="VWX64_000125"
     CDS             complement(116724..118904)
                     /locus_tag="VWX64_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9189696.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVAAYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(119190..120116)
                     /locus_tag="VWX64_000126"
     CDS             complement(119190..120116)
                     /locus_tag="VWX64_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9189697.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(120109..120801)
                     /gene="ftsE"
                     /locus_tag="VWX64_000127"
     CDS             complement(120109..120801)
                     /gene="ftsE"
                     /locus_tag="VWX64_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU9189698.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(120819..121914)
                     /gene="prfB"
                     /locus_tag="VWX64_000128"
     CDS             complement(join(120819..121841,121843..121914))
                     /gene="prfB"
                     /locus_tag="VWX64_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU9189699.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(122022..122678)
                     /locus_tag="VWX64_000129"
     CDS             complement(122022..122678)
                     /locus_tag="VWX64_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9189700.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(122986..123696)
                     /locus_tag="VWX64_000130"
     CDS             complement(122986..123696)
                     /locus_tag="VWX64_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189701.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(123696..124460)
                     /locus_tag="VWX64_000131"
     CDS             complement(123696..124460)
                     /locus_tag="VWX64_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189702.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(124460..125416)
                     /locus_tag="VWX64_000132"
     CDS             complement(124460..125416)
                     /locus_tag="VWX64_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9189703.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(125420..126289)
                     /locus_tag="VWX64_000133"
     CDS             complement(125420..126289)
                     /locus_tag="VWX64_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9189704.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(126557..127717)
                     /locus_tag="VWX64_000134"
     CDS             complement(126557..127717)
                     /locus_tag="VWX64_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9189705.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(127819..128067)
                     /locus_tag="VWX64_000135"
     CDS             complement(127819..128067)
                     /locus_tag="VWX64_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU9189706.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKETFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(128146..128736)
                     /gene="clpP"
                     /locus_tag="VWX64_000136"
     CDS             complement(128146..128736)
                     /gene="clpP"
                     /locus_tag="VWX64_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU9189707.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(128910..129539)
                     /gene="upp"
                     /locus_tag="VWX64_000137"
     CDS             complement(128910..129539)
                     /gene="upp"
                     /locus_tag="VWX64_000137"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU9189708.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLNLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(129628..130095)
                     /locus_tag="VWX64_000138"
     CDS             complement(129628..130095)
                     /locus_tag="VWX64_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU9189709.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(130114..130671)
                     /locus_tag="VWX64_000139"
     CDS             complement(130114..130671)
                     /locus_tag="VWX64_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9189710.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            130796..131641
                     /locus_tag="VWX64_000140"
     CDS             130796..131641
                     /locus_tag="VWX64_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9189711.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            131700..132875
                     /locus_tag="VWX64_000141"
     CDS             131700..132875
                     /locus_tag="VWX64_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9189712.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            132895..133350
                     /locus_tag="VWX64_000142"
     CDS             132895..133350
                     /locus_tag="VWX64_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9189713.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(133370..134124)
                     /locus_tag="VWX64_000143"
                     /pseudo
     CDS             complement(133370..134124)
                     /locus_tag="VWX64_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            134330..135665
                     /locus_tag="VWX64_000144"
                     /pseudo
     CDS             134330..135665
                     /locus_tag="VWX64_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(135705..136649)
                     /gene="manA"
                     /locus_tag="VWX64_000145"
     CDS             complement(135705..136649)
                     /gene="manA"
                     /locus_tag="VWX64_000145"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU9189714.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(136770..137066)
                     /locus_tag="VWX64_000146"
     CDS             complement(136770..137066)
                     /locus_tag="VWX64_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU9189715.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
BASE COUNT        40150 a        27645 c        27874 g        41428 t
ORIGIN      
        1 tattaaaata gtctcattct gatgagaaaa ctattctatt tatactgcat cgttgtgtaa
       61 ggaatgatga aagatgagtg aaaattatca agttggaatg tttgtatcta aatatattag
      121 catgtattta gatcagatgt ctgcaatcct ttatatatga gattgattac gatatagtta
      181 aagtgttagt tcaatagtaa atatatcatt ctaagtctat tttatatata aagtatattg
      241 tttaacgttt gatagaaaag atgctatact agaagtagga tgtaatggca aaatctaata
      301 ctaataagcg ctatgcaata cgtaaactcg gaaagatttt tggttctgcg gtaatcgggc
      361 taactttatt tttaggagga atctgaatac aagttttgct catgctgctg atgggattca
      421 atatgtcaga gatgatacta gagataaaga agagggaata gagtatgatg acgctgacaa
      481 tggggatatt attgtaaaag tagcgactaa acctaaggta gtaaccaaga aaatttcaag
      541 tacgcgaatt cgttttgaaa aagatgaaac aaaataccgt agtgaaaatc ctgttacaat
      601 tgacggagag gatggctatg taaccacgac aaggacctac gatgttaatc cagagactgg
      661 tcatgttacc gaaaaggtta ctgttgatag aaaagaagcc acggatacag ttatcaaagt
      721 tccagctaaa agcaaggttg aagaagttct tgttccatgt gctactaaat atgaagcaga
      781 caatgacctt tctgcaggac aggagcaaga gattactcta ggaaagaatg ggaaaacagt
      841 tacaacgata acttatgatg tagatggaaa gagtggacaa gtaactgaga gtactttaag
      901 tcaaaaagaa gactctcaaa caagagttgt taaaaaagga accaagcccc aagttattgt
      961 ccaagaaatt ccaatcgaaa cagaatatct cgatgaccca actcttgata aaggtcaaga
     1021 agtaggagaa attggtaaaa ttactcttac tacaatctat gctgtagatg aacgtgatgg
     1081 aacaattgaa gaaactactt ctcgtcaaat tactaaagag atggtaaaaa gacgtataag
     1141 gagagggacg agagaacctg aaaaagttgt tgttcctgag caatcatcta ttccttcgta
     1201 tcctgtatct gttacatcta accaaggaac agatgtagca gtagaaccag ctaaagcagt
     1261 tgctccaaca acaggctgga aacaagaaaa tggtatgtgg tatttttata atactgatgg
     1321 ttccatggca acaggttggg tacaagttaa tggttcatgg tactacctca acagcaacgg
     1381 ttctatgaaa gtcaatcaat ggttccaagt tggtggtaaa tggtattatg taaatacatc
     1441 gggtgagtta gcggtcaata caagtataga tggctataga gtcaatgata atggtgaatg
     1501 ggtgcgttaa cagattcctc cctgcgacaa aattgataat agtatgtctg aatatataat
     1561 tatccccaat tattcacccc taatctaaaa accatccaga atccttgcct tagcttagat
     1621 cctggatggt ttcttttttc acccaatggg tgttttttac tagacaaaaa agagtttccc
     1681 ctttatggta taagtgtaga aaaaaacaca aaaagaaagg aaactcacat gaacagttta
     1741 ccaaatcatc acttccaaaa caagtctttt taccaactat ctttcgatgg aggtcattta
     1801 acccagtatg gtggtcttat cttttttcag gaactttttt cccagttgaa actaaaagag
     1861 cagatttcta agtatttagt aacgaatgac caacgccgct actgtcgtta ttcggattca
     1921 gatatccttg tccagttcct ctttcaactg ttaacaggct atggaacgga ctatgcttgt
     1981 aaagaattgt cagctgatgc ctactttcca aaattgttgg aaggagggca gcttgcttca
     2041 cagccaacct tatcccgttt tctttccaga actgacgagg aaacagtcca tagtttgcga
     2101 tgcctcaacc ttgaattggt cgaattcttt ttacagtttc accagctaaa ccaactcatt
     2161 gtagatatcg attctaccca tttcacaact tatggcaagc aagaaggtgt tgcttataac
     2221 gctcactatc gtgctcatgg ctatcatcct ctttatgctt tcgaggggaa gacaggttat
     2281 tgtttcaatg ctcagcttcg tcctggtaat cgttattgtt ctgaagaggc agacagcttt
     2341 atcacacctg ttttagaacg gtttaatcaa cttctctttc gaatggatag tggctttgcg
     2401 acccccaaat tatacgattt aattgaaaaa acagggcaat actacctcat aaaactcaag
     2461 aaaaatactg ttctgagccg tcttggagac ctttccctcc cttgcccaca ggatgaggac
     2521 ttaaccatct tgccccactc cgcctactca gaaactctct atcaagcagg atcttggtcg
     2581 cacaagcgtc gtgtctgcca gttctctgaa cgaaaagaag gaaacttgtt ctacgatgtt
     2641 atttctctcg ttacaaatat gacgagtgga acaagccaag accagtttca gctttatcgt
     2701 ggacgtggtc aagccgagaa tttcatcaag gagatgaagg agggattttt tggcgataaa
     2761 acggatagtt caaccttaat caaaaacgaa gttcgtatga tgatgagctg tatcgcctac
     2821 aatctctatc tttttctcaa acatctagct ggaggtgact tccaaacttt aacaatcaaa
     2881 cgcttccgcc atctttttct tcacgtggta ggaaaatgtg ttcgaacagg acgcaagcag
     2941 ctcctcaaat tgtctagtct ctatgcctat tccgaattgt tttcagcact ttattctagg
     3001 attagaaaag tcaacctgaa tcttcctgtt ccttatgaac cacctagaag aaaagcgtcg
     3061 ttaatgatgc attaaagaac agtcgagatg aaaaaatcgt gtgacgcacc aagggaggag
     3121 tctgcccttt tgaggaaatc tagcgaggaa aaacgatact ggaacagcag aaagtaaaac
     3181 tgacctcatg aggaggaaga aagtggctca tgaggtcagg ggttttgtaa gttacatcta
     3241 gttgagagag gtatgaatga tttgggatta tatataaaaa gctatagata aggtcatctt
     3301 atagcgacta taaaaaagtg aacaagccta gtcttctgta cattagaatt cagatttgtt
     3361 cactttttgt ttaatactca atgaaaatca aagagcaaac tagaaaacta gtcgcaggtt
     3421 gctcaaagta ctgctttgag gttgtagata gaactgacaa agtcagtcac atatataatc
     3481 caaggtgacg ttgacgcggt ttgaagagat ttttgaagag tataagtctt tgattttgag
     3541 actaaggaga gtcagggtca aagtagtgaa tgattctgaa ataactcata atagtctctt
     3601 gagaggacag ataagagtaa caaatatggt gctactcatg tgtcttgcat tttgatttac
     3661 aaacagcgaa gaaagtatag gaagctgaaa taaaatatag atgaatcaat ttggagagtc
     3721 aacgcaatct atggcaatat tttcgaagct agggggaagc attttaattt caatgtacta
     3781 ggcctcttct acagctagct agagtttcaa ttgtagatgt tctttgaaat aatatcttag
     3841 cgatttattg gtattagaag atttagagaa attctttctc aataaataaa catagcgtca
     3901 ccaaaactga agaagcggta gtgttcttgg atggaatggt ggtaggcatc taagactaat
     3961 tcacggcctg caaaggcaga aaccaacatg accagagttg attttggcag gtggaagttg
     4021 gttgagaagg catccacgac cttccactca tacccaggtt tgataaagat attggtccaa
     4081 ccagaatctg cttggatttg cccatcaaac ttggaaccaa tagtttccaa ggtgcggata
     4141 gaagtggttc cgacagcgat gacacgacca ccattttttt tgacagagcg aagggtggca
     4201 gcagcttcct cagaaagttg atagaactct gagtgcattt cgtgttcgtc cagattatcc
     4261 acagaaacag gtctaaaggt tccgagtccg acatggagag tcagatagac tagatgaaca
     4321 cccttagctt ggatttctgc cagcagttct ttggtgaagt gaagaccagc agtcggtgct
     4381 gcagcagagc cgctttcctt ggcgtagacg gtttgataac gttcacggtc atctaatttt
     4441 tcgtggatat aaggtggcag aggcatttct cccagacttt ccaagacttc taggaaaatt
     4501 ccttggtatt caaagcggac aatgcgtccc ccgtgggtca attcttctgt aacgacagcg
     4561 ctgaggcggc catcaccaaa gctgatacga gtaccgacct tgaggcgttt ggcaggttta
     4621 gccagaactt cccactcgtc tccactagtg ttcttaagga ggagaagttc cacatgacct
     4681 cctgtctcca ctttttgacc atagaggcgg gcagggagaa ctcgggtgtc gttcatgaca
     4741 agggcatcac caggttccag catattaata atagagtgga agtgtttatc ttgcatttct
     4801 cctgtctcac ggttgacgat gaggagtttg gaggcatcac gtttttcaag gggcgtttgg
     4861 gcaatcaatt cctctggcaa gtggaaatca aaatcagctg tattcatata tctgttcatt
     4921 ctttctaagt tctaatccta tccattataa cacgtttcaa gtttggacgc tcttttttta
     4981 gaaattaaat cgttttcact tgacaaaaat tggtctatac catataataa atatagacag
     5041 aaatggagga tgaaaagatg aaagttatta aagttgaaaa ccaagttcaa ggtggaaaag
     5101 ttgcttttga gattttgaag gaaaaattgg ctaatggagc tcaaactcta ggacttgcga
     5161 caggaagtag cccacttgaa ttttacaagg aaattgttga gagtgacctt gatttttcaa
     5221 atctaaccag tgtcaacctt gatgagtatg tgggccttga tggggacaat ccacagtctt
     5281 atcgttactt catgcaagaa aacttgttca accaaaaacc atttaaagaa agtttcttgc
     5341 ctcgtggtgt taaggacaat gctgaagctg aagttgaacg ctacaaccaa attttggctg
     5401 accatccagt tgacctccaa atcttgggaa tcggtcgcaa tgggcatatc ggctttaatg
     5461 agcctggtac tccatttgat agtcaaacgc atctagtaga acttgaccag tctactatcg
     5521 aagccaatgc tcgcttcttt gccaagattg aagacgtccc aacccaagct atttcaatgg
     5581 ggattaaaaa cattttggat gccaagtcta ttattctttt tgcttatggt gagtcgaaag
     5641 cagaagccat tgccggaaca gtatctggcc cagtgactga gaacctacct gcaagtagcc
     5701 tccaaaatca ccctgatgta accatcatcg cagatgctga agcgcttagc ttactcgaaa
     5761 aataaaaaag caatgttcta ttgaacgctt tcaactcttg tataaatgga agaaaaaatc
     5821 aaaattaaac cgcatttttg cttgacaatt attcctttta cgtgtagaat gaaatagata
     5881 ttgaacttga agggagtgaa aaaaatgtct aaaacagtag tacgtaagaa tgaatctctt
     5941 gacgacgcac ttcgccgttt caaacgtgcg gttactaaag ctggtactct tcaagaaaca
     6001 cgcaaacgtg aattctatga aaaaccttct gtaaaacgta aacgtaaatc agaagtagct
     6061 cgtaaacgta aaaaattcta attgaaatga aaggctagag aaatctagtc ctttttcttt
     6121 taaataaata ctccaaagcc tgcaaaaatc tgaaacttcc tcctacaatt tgatataata
     6181 gagagaagaa ttcatttgaa ggaggaaatg atgtcggttt tagtaaaaga agtgattgaa
     6241 aagcttagac tagatattgt ctatggtgaa ccagaattgc ttgaaaagga aatcaataca
     6301 gcggatatta cgcgacctgg tcttgaaatg acaggctatt ttgactacta tacaccagag
     6361 cggattcaac ttttggggat gaaggagtgg tcttatctga tcagcatgcc ttccaacagc
     6421 cgttatgaag ttttgaaaaa aatgtttcta cctgagacac cagcagtcat tgttgcccgt
     6481 ggtttggtgg ttccagagga gatgttaaag gctgctagag aatgtaagat tgctatttta
     6541 accagccgtg cagctaccag tcgtttatct ggagagttat ctagctatct ggattctcgt
     6601 ttggcagaac gtaccagtgt gcacggtgtc ttgatggata tttatgggat gggcgtcttg
     6661 attcagggag atagtggaat tggtaagagc gagacaggtc ttgagcttgt caaacgtggt
     6721 caccgtttgg tagccgatga ccgtgtcgat atctttgcca aggatgagat tactctctgg
     6781 ggtgaaccag ctgaaatttt gaaacacttg attgaaattc gtggggttgg tattatcgat
     6841 gttatgagtc tctacggtgc gagtgctgtc aaggattctt cacaggttca gcttgctgtc
     6901 tatttggaaa attacgatac gcataagacc tttgatcgtc ttggaaacaa tgcagaggaa
     6961 cttgaagttt ctggcgtagc cattcctcgt attcgtattc cagttaaaac aggtcgtaat
     7021 atctctgttg tgattgaggc agctgccatg aattatcgtg ccaaggaaat gggctttgat
     7081 gctacccgtt tgttcgacga acgactgaca agtctcatag ctcgaaatga ggtgcaaaat
     7141 gcttgatcca attgctattc aactaggacc cctagccatt cgttggtatg ccttatgtat
     7201 tgtgacaggc ttgattcttg cggtttattt gaccatgaaa gaagcaccta gaaagaagat
     7261 cataccagac gatattttag attttatctt agtagccttt cccttggcta ttttaggagc
     7321 tcgtctctac tatgttattt tccgatttga ttactatagt cagaatttag gagagatttt
     7381 tgccatttgg aatggtggtt tggccattta cggtggtttg ataactgggg ctcttgtgct
     7441 ctatatcttt gctgaccgta aactcatcaa tacttgggat tttctagata ttgcggcgcc
     7501 tagcgttatg attgctcaaa gtttggggcg ttggggtaat ttctttaacc aagaagctta
     7561 tggtgcaaca gtggataatc tggattatct acctggcttt atccgtgacc agatgtatat
     7621 tgaggggagc taccgtcaac cgactttcct ttatgagtct ctatggaatc tgcttggctt
     7681 tgccttgatt ctgattttta gacggaaatg gaagagtctc agacgaggtc atatcacggc
     7741 cttttacttg atttggtatg gtttcggtcg tatggtcatc gaaggtatgc gaacagatag
     7801 tctcatgttc ttcggccttc gagtgtccca atggctgtca gttgtcttta tcggtctcgg
     7861 tataatgatc gttatttatc aaaatcgaaa gaaggcccct tactatatta cagaggagga
     7921 aaactaaatg ttagaagttg catatattct tgttgcccta gctgtgattg tctttttggt
     7981 ctatctgatc attactgtac aaaagcttgg tcgtgtcatc gatgaaacag aaaagacgat
     8041 taaaaccttg acttcagatg tggatgtgac cttgcatcac accaatgagt tgttggctaa
     8101 ggtcaatgtc ttggcagatg atatcaatgt caaggtggct acgattgatc cactcttcag
     8161 tgctgttgca gatttatctc tatctgtttc agacctcaat gaccatgcgc gtgtcttgag
     8221 caagaaagct tcatcagctg gttcaaaaac actcaagact ggtgcaagtc tgtcagctct
     8281 tcgtcttgca agtaaatttt tcaaaaaata aaaaaggaga atccttatgg gtaaattatc
     8341 ctcaatcctt ttaggaaccg tttcaggtgc agctcttgcc ttgtttttaa caagtgataa
     8401 gggcaaacaa gtttgcagtc aggctcaaga ttttctagat gatttgagag aagatccgga
     8461 gtatgccaag gagcaagtct gtgaaaaact gacagaagtt aaggagcagg ctacagattt
     8521 tgttctgaaa acaaaagaac aggttgagtc aggtgaaatc actgtggaca gtatacttgc
     8581 tcaagctaaa tcctatgctt ttcaagcgac agaagcatca aaaaatcaat taaataatct
     8641 caaggaacaa tggcaagaaa aagccgaagc tcttgatgac tcagaagaga ttgtgattga
     8701 tataacagaa gaataaacca tcaccatctc cggacggact atgtatctgg ggatggtgat
     8761 ttttatctgg aatctagtct ttgtggtata ataattacta tgcagaaaaa accaacgtca
     8821 gcctatgtgc acatcccatt ttgtacccag atttgttatt attgtgattt ttcaaaggtc
     8881 ttcatcaaaa atcagccagt cgacagctat ttagagcatc tgctggaaga gtttcgttct
     8941 tatgatattg aaaagttgtc aaccctttat atcggtggtg gaacaccgac agccctgtcg
     9001 gctccgcaac tggaggtgtt actgaatggc ttgactaaaa acttggattt gtctgtcttg
     9061 gaagagttga ccattgaagc caatccaggc gatttggatg cggataagat agctgttttg
     9121 aaaaattcgg ctgtcaatcg tgtttcgcta ggtgtccaga cctttgatga taagatgttg
     9181 aaaaagattg ggcgcagtca tttggagaag gatatttatg aaaatatcga tcgcctgaaa
     9241 ctggctggtt ttgacaacat ctccattgat ttgatttatg ctctgcctgg tcagaccatg
     9301 gagcaagtaa aggaaaatgt ggctaaagcc attggattgg atattcccca catgagtttg
     9361 tatagtttga ttttagaaaa ccatacggtc tttatgaacc ggatgcgacg tgggaaattg
     9421 cctctgccta aggaggaact agaagcggag atgtttgagt acatcattgc agagctggag
     9481 cgagcgggtt ttgagcatta tgagatttct aatttctcca aacccggctt tgaaagtcgt
     9541 cataatctca tgtactggga caatgctgaa tactatggta ttggtgcagg ggcatctggt
     9601 tatgtcaatg gagtacgcta taaaaatcat ggtcccattc gtcattatct cagtgcggtt
     9661 gaggaaggca atgcttgtat tacagaagat cacctgagtc aaaaggagca aatggaagaa
     9721 gaaatgttct tgggactccg caagaaatcc ggggtttcca tggcgcgatt tgaggaaaaa
     9781 tttggacagt cttttgctgg actttatgga gaaattgtca gagatttggt tcaacaaggc
     9841 ctcatgcaga ttgagggtga ccacgttcgc atgacaaaga gaggtctctt tttgggagat
     9901 actgtagcag aacgatttat tttggagtag gatcatgggc ttaacttatc aaatgaaaat
     9961 gaaaattcct tttgatatgg ctgatatgaa cggtcatatc aaacttccag atgtgatttt
    10021 gctgtcactg caagtttcag ggatgcaatc gattgaactg ggagttagtg ataaggccat
    10081 tttggaagac tataatctgg tctggattat cgcagaatat gatattgagg tggttcgttt
    10141 gcctcgtttt gcggaagaaa ttaccatcga aacggaagcc ttgagctaca atcgactttt
    10201 ttgctaccgt cgctttacta tttataatga agcggggcag gagctcatcc atatgatggc
    10261 gacctttgtt ctcatggacc gcgacagtcg aaaagtccat gctgttgaac ctgagattgt
    10321 ggctccttac cagtctgatt ttgataaaaa acttatccgt ggaccgaagt atgaatcctt
    10381 ggaagagccg atcagcaagg attaccatgt tcgtttttac gacttggata tgaatggtca
    10441 tgtcaataac agtaaatact tggactggat ttttgaggtc atgggagcgg attttttgac
    10501 ccactatatt cccaagaaaa tcaacctcaa gtatgtcaag gaagttcgac caggtggggt
    10561 gattacatcg gctgttgaac ggactggact ggaaagcaag catgaaatta caagtgatgg
    10621 ggttatcaat gcccaagcaa tcattacttg gcaagaaata aaaaaggttt agggagaaat
    10681 agatgaaata taaaggctat ttaattgatt tagacggaac catttataag gggaaagacc
    10741 gaatccctgc tggagagact tttgttcatg aattgcaaaa gcgggacatt ccctatctct
    10801 ttgtaaccaa caatacaacc cgcactccag agagtgttaa ggagatgttg gctcagaatt
    10861 ttaatatcga tacgcctcta tcgactgtct acacagcgac tttggcaacc atcgactata
    10921 tgaatgattt ggggcttgaa aagactgtct atgtcgtcgg agaagcagga ctcaaggaag
    10981 ccatcaaggc ggctggttat gtggaagaca aggaaaaccc tgcctacgtg gtagttggtc
    11041 tggattggca agtcgactat gaaaaatttg ccacagcaac tcttgctatt caaaagggtg
    11101 cccattttat cggaaccaat cctgacctca acatcccgac ggaacgtggt cttttgccag
    11161 gtgctggctc actgattacg ctgcttgaag tagcgacacg agtgaagccg gtttatatcg
    11221 gaaaaccaaa tgccatcatt atggacaagg cggttgagca cttaggtttg gaacgtgaag
    11281 agttaatcat ggttggggac aattatttga ctgatatccg ggctgggatt gacaatggca
    11341 ttccaacgct cttggtgacg acaggtttta ctaaggcaga agaagtggct ggcctgccaa
    11401 tcgcaccgac acatgtggtt tctagccttg cggagtggga ttttgatgaa aactaaattg
    11461 accttttggg gctctatgct ctttctcctc tccctctcaa tccttctgac catttatctg
    11521 gcttggattt tctatcctat ggagattcag tggctaaact taacgaatcg agtctatcta
    11581 aaaccagaaa ccattcaata caattttcat atcttgatga attatctgac caatcctttt
    11641 agtcaggtct tacagatgcc tgattttcgt tcgtcagcag ctggtctgca ccatttcgca
    11701 gtggtcaaga atctctttca tttggttcag ctagtagctc tagtgacact gccaagtttc
    11761 tatgtctttg tcaataggat tgtgaaaaag gactttttgt ctctttatcg aaaaagtctc
    11821 ctggctctag tagtcttacc tgtgatgatt ggacttgggg gagttttgat tggttttgac
    11881 caattcttta ctcttttcca tcaaattctc tttgtgggag atgatacctg gctttttgat
    11941 ccagccaagg atcctgttat tatgattttg ccagagacct tctttcttca tgccttcctc
    12001 ctcttttttg ccctctatga aaacttcttt ggctatctgt atctgaaaag tcgtaggaag
    12061 tgaaaggaaa gatgttttta atttacatat ataaaaatat atatcgttta aaaccatcgt
    12121 taagagtgaa ttaaccaaat ccaattgtgt caatcgttcg caaaaagcct atttttcttg
    12181 aaaaaatagg ctttttttct aaaaatccct agtcaagcgc tttatttttt tgtataatag
    12241 aagtagcaaa gtatagataa gaagagaaaa gcatgattac actatttcta tcaccgagct
    12301 gtacatcatg tcgtaaggct aaggcctggt tagaaaaaca taaggttccc tttgtggaac
    12361 acaatattat gaccagtcct ttaacaagaa aagaattgca acacatcctt tccttgaccg
    12421 aaaatggtac tgatgacatc atttcaactc gttcaaaaat ttttcaaaaa ttgaatattg
    12481 atgtagagag tatttcggta tcggaattgc ttcatttgat tgagcagtat cctagtcttt
    12541 tgcgtcgtcc aattattatt gatgccaagc gtatgcaaat cggttttaat gaagatgaga
    12601 ttcgtgcttt tctccctcgt agttatcgta agcaagaact aaaagaagca agaatgagag
    12661 ctggtattag ttaatgaaca aacagtatag ttacccacta gatttgtcgt ggagcactga
    12721 agaacttgct tcagtgcttt ctttttttaa tgatgttgaa gctgcctatg aaggcaaagt
    12781 agaggctaaa aagttactgg actcctataa gggattcaaa gcagtcgtgc caagcaagag
    12841 cgaagagaaa cgtttgggac gagaatttga aacggttagt ggctattcac tttaccgagc
    12901 agttcaggct gccaaagaaa aaggggaagg aaagatttct cttggaaagt aaatttgaat
    12961 ttgctaaaga gcttgttaag aaagcaggcc agtacattct tgaccatatg caggaagact
    13021 tgcgtgttga aaccaagtcc tctccaacag atttggtgac cagactggac aaagaagttc
    13081 aggaactctt ggttggtgag attttgtccc gttatcctga ggataagatt tgtgctgaag
    13141 aaggttgtct gcgagcctcg gttcaagagg gcaaggtttg ggtcattgat cccattgatg
    13201 gtaccaataa ttttgtagcc cagcaggaag attttgctgt tatgatggct tattttgaaa
    13261 atggtcaggg acagtttggt ctgatttatg atgtggtcaa aggggattgt taccacggtg
    13321 gtggggaatt tccagtttgt ctaaatgata ggcccctagc tccttttaaa actaaaccac
    13381 ttggagattt tctcattgca gggaatagtg gtatgctgga aaccaatgaa tgggggctgg
    13441 ctgatttgag ccgagcggtt cttggtgttc gtgtctatgg aagtgcggcc attagttttg
    13501 ccaagatttt gtcagggcat ttgttgacct atctcaccta tctgcaacca tgggattatg
    13561 ccgcagctag tattttaggg gaaagtctgg gctatcgggt tgtgaccctt tttggtgaag
    13621 ctcctgattt tcaaaccaga cagccggtca tgatggtgcc tcttgagatg caggaggaaa
    13681 ttcagtccta tatttacgaa aggaaaagaa cttaaatgaa atttccagaa ggatttgttg
    13741 aaaaatataa agaaatacta ggagatgagg caagagattt tcttgcctct tttgaggagg
    13801 aagcggtttc ggcctttcgg gtcaatccct taaaagaaga gcaactttcc ttttctgatg
    13861 ccattactca aaccccttgg ggccactatg ggaaggtttc agggaaatcg cctgagcatg
    13921 ctacaggttt agtttattcg caagaacctg ctgctcaaat ggtggctcaa gtagcccaac
    13981 ccagtcctgg tatgaaggtc ttggacttgg ctgctgcacc ggggggcaaa tcaactcaac
    14041 tggcagccta tctagcaggg gaggggctac ttgtttccaa tgaaatttca agcaaacggg
    14101 ctaagatttt ggttgaaaac atggagcgtt ttggagcgac aaatgtcgtg gtgaccaatg
    14161 aatctgccga ccgcttggtc aaggtcttta aaggctattt tgacttaatc gttcttgatg
    14221 ccccttgctc tggtgaagga atgtttcgta agaaacctga tgctatggac tattggagct
    14281 tagattatcc gagtcaatgt gctagcttgc aaagagaaat tctggaggat gcagtgacca
    14341 tgttagctga aggtggtcgt ctggtttatt cgacctgtac ctgggcaccc gaggaaaacg
    14401 aagagattgt caattggttg ctggaagagt atgattttga cttgttgcca gtagagcata
    14461 tcaatggaat ggtagctggt attgacctgc aagaaacggc tcggatgtac cctcatcagt
    14521 ttaagggaga gggtcagttt gttgcccatc tacagtttaa gggtaacaat ccagctccta
    14581 aatttaaggc aagtaagagt aacctcagcc gtgaacaagt tgccttgtgg caggaatttg
    14641 cccaaaacca tttgaaggtc aatctaccgg gtatcttgca gatttttgga gaccagcttt
    14701 atctcttgcc agaacttttg ccagatttag ggaagctcaa gattgctcgc aatggactgc
    14761 atctgggtac ttttaagaag aaacgctttg agcccagttt cgctcttggt ttagccttga
    14821 aaccgagtca ggtcgaacag tcggttgaaa ttggccaaga agcgtttgtc aagtatgcgg
    14881 ctggagaaac cgttcagctg gcagaaagtc tgccaaatgg ttggtaccaa gttttggtta
    14941 aaggcaatgg cttgggcttt gcaaaggtta ctggaaatgt tttgaaaaat tattttccaa
    15001 aaggcctcag attcaaatga aaatgctagt caaatatctt attctatgtt atagtgaaag
    15061 tatggatttt tttagtagga tgattcttga tatcttgatt gccatcacat gtagttttac
    15121 tactcgatga aaatcaaaga gcaaactagg aagctagcca tagatagctc aaaacactgc
    15181 tttgaagaga ttttcaaaga gtacaagaag tttagttatt agcgttctta ccgcttgtaa
    15241 actagatttc tcataaaata gaatcttttc cttttagttg taaactagtc tgggagagta
    15301 gagaggtttg agataccttt ctagcttttg gattatcatc taagaagagt aatttccctt
    15361 gcattaaaaa ggggaaaaag agacacgaaa tgactataat gggtgacaat gggggaaggg
    15421 atagacaaga gattttatcc acatatgaaa aaaggaggtt aggaaagagt aatatagcct
    15481 atattatata aataatcaat tgcgcagaaa tttggtaaga attcatgcgt caactcataa
    15541 agaactactt aaaaaattca cagtattcat aattattttc gaggagaaaa acagtgaaaa
    15601 aaagaaaaaa gcttgctctg tctcttatcg ctttttggct gacggcttgt ttagtaggct
    15661 gtgctagctg gattgatcgt ggagaatcca taacggctgt tggctcaact gccttgcaac
    15721 ccttggttga agtagcggca gatgaatttg gcacgatcca tgttggaaaa acggtcaatg
    15781 tccaaggggg aggttctggt acaggcttgt cccaggttca gtctggggca gttgatatag
    15841 gaaactcaga tgtatttgct gaggaaaaag acggaattga tgcttctgct cttgttgacc
    15901 acaaggtcgc ggtagctggc ttggctctga ttgtcaataa ggaggttgat gttgataacc
    15961 taacgacaga gcaacttcgt caaatcttca taggtgaggt aaccaattgg aaagaggttg
    16021 gtggtaagga cttacccatc tctgttatca atcgggcagc cggctctggc tctcgtgcta
    16081 cctttgatac tgtcattatg gaaggtcagt ctgccatgca aagtcaggag caggattcaa
    16141 atggagcggt aaaatcaatc gtatcaaaaa gtccaggagc tatctcttat ttatctctta
    16201 cctatataga tgattcggtc aaaagcatga agttgaatgg ctatgactta agtccagaaa
    16261 atataagtag caataattgg cccttgtggt cttatgagca tatgtataca ttggggcagc
    16321 ccaatgagtt ggctgcagaa tttctcaatt ttgttctctc ggatgagacc caagaaggga
    16381 ttgtcaaagg attgaagtat attccgatta aggaaatgaa ggttgaaaaa gatgctgccg
    16441 gaactgtgac agtgttggaa gggagacaat aatgaatcaa gaagaattag ctaagaaaat
    16501 gttgcttcca tcaaagaatt ctcgtctgga gaaattagga aaaggtttga cctttgcctg
    16561 tctttctttg atagtcatcc ttgtggccat gattttggtt ttcgtagcgc aaaaaggctt
    16621 gtcgaccttc tttgtcaatg gtgtgaatat ctttgacttt cttttgggag gaacttggaa
    16681 tccttctagt aaagaatttg gtgcccttcc tatgattttg ggttccttta tcgttaccat
    16741 tctctcagcc cttatcgcaa caccctttgc tattggtgca gcagttttta tgaccgaagt
    16801 atcaccaaaa ggggcgaaga ttttgcaacc agctattgaa ctcctggttg ggattccttc
    16861 agtagtgtac ggatttattg gcttgcaagt cgtcgttccc tttgttcgca gtgtctttgg
    16921 tgggactggt tttgggattt tgtcagggat ttccgtcctc tttgtcatga ttttgccgac
    16981 cgtaaccttt atgacaacgg atagcttgcg tgcggttcct cgttattatc gtgaagccag
    17041 tttcgctatg ggagccactc gctggcagac tatctggcgt gtgatcttga aggcggcccg
    17101 ttctggtatt ttcactgcag tggtctttgg gatggcgcgt gcctttggtg aggctctagc
    17161 tatccagatg gttgtcggaa actcagctgt tatcccaact tccttgacca caccagctgc
    17221 aactttaact tctatattaa ctatgggaat tgggaacact gtcatgggaa ctgtaaataa
    17281 taatgttctc tggtcactgg ccttggtact gctcttgatg agtttagttt ttaacagtgt
    17341 gattaaattg attacgaaag aaagaggaaa gaaaaattat gcgcgctaag aaattagata
    17401 aacttgcaac agctgtcctc tatacgattg ctagcatcat tgtgacaatc ttggcttcct
    17461 tgattctcta tatcttggtt cggggcttgc cccatatctc ttggtctttc ttgactggaa
    17521 ggtcttctgc ttttcaagca ggtggtggga ttggcattca gctttacaat tcctttttcc
    17581 tattggtcat taccttgatt atttctgtac ctctttctat gggagctggg atttacttgg
    17641 ctgaatatgc taaaaaaggt cctgttacca actttgtgcg gacttgtatt gaaatcttgt
    17701 cctctttacc atcagtggtg gtgggtctct ttggttactt gatctttgta gtccagtttg
    17761 agtatggatt ttcaatcatt tcaggtgcct tggccttgac agtctttaac ttgcctcaga
    17821 tgacgcgtaa tgtagaggat agtttgaaac acgttcacca tacccaacgt gaggctggtc
    17881 tggctcttgg gatttctcgc tgggagacag tggttcatgt tgttattcca gaagcgcttc
    17941 caggtattgt aacgggtgtc gttttggcat ctggtcgtat ctttggcgaa gctgcagctc
    18001 tgatctatac agcagggcaa tcggcgccag ctcttgactg gtctaactgg aatatcctca
    18061 gtgtgactag ccccatctct atcttccgtc aagcagaaac cttggctgtc catatctgga
    18121 aagtcaatag tgaaggcact attccagatg gaaccattgt atcagcaggt tctgccgctg
    18181 tgctcctgat ctttatcctg atttttaact ttggagctcg taagttcgga agctatctac
    18241 acaagaaatt aaccgctgcc taaaggagaa gccatgtcaa catataactg ggatgagaag
    18301 catatcctta cctttcctga agaaaaagta gccctttcta ctaaggatgt ccatgtttac
    18361 tatggtaaaa atgaatccat taaggggatt gatatgcaat ttgaaagaaa taaaattaca
    18421 gctttgattg gtccgtcggg atcggggaaa tctacctact tacgcagtct caatcgcatg
    18481 aatgatacca ttgatattgc taaagtaact gggcagattc tctatcgtgg aattgatgtc
    18541 aaccgtccag aaatcaacgt ttatgaaatg cgtaaacaca ttggaatggt ttttcaacgc
    18601 cccaatccat ttgctaagtc aatttaccgt aatattacct ttgcgcatga acgtgctgga
    18661 gttaaggata agcaagtcct agatgaaatc gtagaaacct cccttagtca ggctgccctt
    18721 tgggatcagg ttaaagacga tctccacaag tcagccttga ccttatcagg tggtcagcaa
    18781 caacgtctct gtatcgctcg tgccatctct gttaagccag atatcctctt aatggatgag
    18841 ccagcctcag ccttggatcc gattgcgacc atgcaactag aagagaccat gtttgagctc
    18901 aagaaaaact ttaccatcat cattgtaacg cataatatgc agcaggctgc tcgtgcaagt
    18961 gactatacag gcttctttta cttgggtgat ttgattgagt atgacaagac tgcaactatt
    19021 ttccaaaatg ccaagctaca gtccaccaat gactatgtat ctggtcactt tggttagaaa
    19081 ggaaaccgta tgacagatgc gattttacag gtatcagacc tgtccgttta ttataataaa
    19141 aagaaggctt tgaatagtgt ttccctatct ttccaaccta aggaaattac agccttgatt
    19201 ggtccatctg gatcagggaa gtcaaccctc ctcaagtctc tcaaccgcat gggagatctc
    19261 aatccagagg tgaccacaac tggatccgtg gtgtacaatg gtcacaacat ctacagtccg
    19321 cgtacagata cggttgaatt acgtaaggaa atcggaatgg ttttccaaca acctaatcct
    19381 ttccctatga ctatctatga gaatgttgtc tacgggcttc gtatcaatgg aattaaggat
    19441 aagcaggttc tggatgaagc cgtagaaaaa gccttgcaag gtgcctctat ctgggatgag
    19501 gtcaaggatc gtctatatga ttcagctatt ggattgtcag gtggtcaaca gcagcgtgtc
    19561 tgcgtggccc gtgtcttggc aactagtcct aaaatcatcc tcttggatga gccaacttcg
    19621 gctttggatc cgatttcagc tggtaaaatt gaggaaacct tgtatggtct aaaagacaag
    19681 tacaccatgc ttctggtaac ccgttccatg cagcaagctt cacgtatctc tgataagaca
    19741 ggatttttcc tagatggaga tttgattgaa tttaatgata ccaagcagat gttccttaat
    19801 ccccaacaca aggaaacgga agactatatt acaggaaaat ttggataagg agatgaaaga
    19861 tgttacgatc tcaatttgaa gaagatttag agaaattaca taaccagttc tacgctatgg
    19921 gacaagaagt gctctcacaa atcaatcgta cggtacgtgc ttttgtcacg catgaccgtg
    19981 acctggcaaa agaggtcatc gaagatgatg cagaagtaaa tgaatacgaa gtgaaactgg
    20041 aaaagaaatc atttgaaatg atcgcactcc aacaaccagt ctctcaagat ttgcgtacag
    20101 tcttgactgt ccttaaggct gtatcagatg tggagcgtat gggggatcac gctgtagcca
    20161 ttgctcaggc aaccatccgt atgaaggggg aagagcgcat tccagctgta gaggaagaaa
    20221 ttaaaaaaat gggacgtgaa gttaaaagcg ttgttgaagc agcacttgat ctttatctta
    20281 atggttctgt tgacgacgca taccgggtgg cctccatgga tgagcaaatt aaccactatt
    20341 ttgaaactat ccgtgacctt gcgactgaag agattaagaa aaatccagaa gccattgtta
    20401 cgggtcgtga ttatttccaa gttatttcct acttggagcg tatcggtgac tatgctaaaa
    20461 atatctgtga atgggttgtc tactttgaaa caggtaagat tgtcgaacta taaaatagtt
    20521 taattctgta taaaaaggag cttgaaatca actgatggct cctttttttg aacgaaaaaa
    20581 tatttttgag ataaaaattt aaaaaacact tgacaagtaa cttggatatc gttataatta
    20641 tacaaaatta acagagaggt tgtttattta tgaaatcaaa aaaatggata tttgttttat
    20701 gtaattttct tgcaagtttc ttcttagtag cttgccagtc aggttctaat ggttctcagt
    20761 cagctgttga ggccattaag caaaagggga aattagttgt ggcaaccagt cctgactatg
    20821 caccctttga atttcaatca ttggttgatg gaaagaacca ggtagtcggt gcagacatcg
    20881 acatggctca ggctatcgct gatgaacttg gggttaagtt ggaaatctca agcatgagtt
    20941 ttgataatgt tttgaccagt cttcaaactg gtaaggctga cctagcagtt gcaggaatta
    21001 gtgctactga cgagagaaaa gaagtctttg atttttcaat cccatactat gaaaacaaga
    21061 ttagtttctt ggttcgtaag gctgatgtgg aaaaatacaa ggatttaact aacctaaaaa
    21121 gtgctaatat tgcagcccaa aaagggactg ttccagaatc aatggtcaag gaacaattgc
    21181 caaaagttca attaacttcc ctaactaata tgggtgaagc agtcaatgaa ttgcaggctg
    21241 gaaaaataga tgctgttcat atggatgagc ctgttgcact tagttatgct gctaaaaacg
    21301 ctggcttagc tgtcgcaact gtcagcttga agatgaagga cggcgacgcc aatgccgttg
    21361 ctcttagaaa aaatagtgat gatttgaaag aagtggtaga caaggtcatc caaaaactta
    21421 aggatgaagg aacttaccaa agctatcttg aaaaagcagc aagtctaact gaagttgaag
    21481 aataagaaaa agcagagttg gatgtcattc caattctgct tttaaatagt ttaaaacatt
    21541 ttccagattg tctagggaca ccttggcaaa ttgataagga caggtgctta aataggcctc
    21601 ttcaaagaag tccaagccca gttgactgtg tttgagactg gcgattttag gatactgtct
    21661 caggtctagc aataaaccat cgtgtagggg ataatgagga aggggacaag gtgttttagt
    21721 tatcctttcc tcgatttgtt tttggtaaga ttcatgattg gtcaagcgag ccaaacgatt
    21781 tttttcaaac aattgactgt caatatagag tgacagggcc ttttgcataa tgaggttgct
    21841 gtcgtagtct aggatatttt tgtaggccac aaatgcttct ttgatagcat ttggaagaat
    21901 gagtgctgta atacgaaggg caggaaaaag gctggtcgag aaggacttga tataaatgac
    21961 atgctcctct gtatcaagat agtggaaggt ttggcccttc ttggagtcca aatcacccag
    22021 ataatcgtcc tctacgatat agacatcata cttggcagct aagttaagaa tagatagttt
    22081 gtcttgctca gaataggaat gtcccagagg atagtgaaat ctaggaatgg tgtagaaaaa
    22141 tttaattttt cctgttttga agtggccttc cagctcctcc aagtcaatcc catcaatgcc
    22201 tcgttcaatc gtttgatagt ccagcccctg tgcaatcaag aggcgattca tccgatggta
    22261 ggttggctgt tccaccaaga tttccttggc ttgtctagga aaggatattt gagagaggat
    22321 aaacaaggct tgttgggttc cagaagtcag tactagttgg ttagccttgc agtagagagc
    22381 ttgctcaaat aggagtttgt gaatggactg tcttaggtct tctaatcctt cttgattgtc
    22441 atagtagttg aagaggtagt tttctcgtcc aatcaaggtt tcattgacac agagtcggaa
    22501 atcgtcatag gcactggcat gttcgtcggt aacctcgatt tctaggtctt gatgttgccc
    22561 ttgttctaat acatagtagc cactctgagg cttggcatag aggtattgtt cgtgccgtaa
    22621 ttccagcagg gctcgttgaa tggtgtcctt gctgcagtga aagtcaaggc tcagttgacg
    22681 gatagaaggc aggcgactac ccgtcggaaa tcgttcagac tcgataccat ttttcagata
    22741 ggaaacgacc tctttgtact tgctttgttt cttcattcca gacctccctt gattttgtta
    22801 cattgtaccc ttttttttcc ttcttggcaa tgtctagagc gtttctctcg ttcacatcta
    22861 ggggcaaatg tggtatactt aggagtaaga tttatagaat aacagacaag aaagtgaatg
    22921 gataagaacg tgcaggaacc agtgaaatta tttcaataca atactcttgg agccttgatg
    22981 gctggccttt atggtggtac tatgacagta ggagaattgc tagaacatgg tgaccttggt
    23041 ttgggaacct tggattccat tgatggggaa ttgattgtct tggatggcaa ggcttatcag
    23101 gccaaagggt caggagacca gccagaaatt gtggaagtgt caccagatgc ccttattcct
    23161 tacgctgcag tggtaccgca tcaggcagag gtcatttttc gccagcgctt tgagatgaca
    23221 gacaaggaat tgaaagaacg aattgagtct tattatgatg gggaaaatct tttccgctct
    23281 atcaagattc ggggggaatt tttacatatg catgtgcgta tgattcctaa gtcaacaccc
    23341 gataccaagt ttgctgatgt cgcaacccat caaccggaat atagtcgtga caatgttgcg
    23401 gggactattg ttggtttctg gacgcctgag attttccatg gggtcagtgt ggcaggctac
    23461 catctgcact tcatatcaga tgatttgacc ttcggtggac atgtcatgga ttttgtcatc
    23521 aaggaaggca ttatcgaggt gggagcagtt gaccagttgg accaacgttt cccagtccaa
    23581 gaccgtcaat acttgtttgc taagttcaat gttgacgaga tgaaaaaaga tattgaaaag
    23641 gcagaatagg agaagaaaat gaccattcat atcattatta ccatgttgct gttgctagct
    23701 tttctgatag gaagcatttg gtttgccaaa aagaaatatc agattaatct agctgtcttg
    23761 ggcttgggtg cagtcgcttt ctttgtctct tcgcagattt tggaaaaact ggtgcatatc
    23821 ttgattttgc accctcaaaa agacggtagt attgccctct tgcaagatca tccgcttatc
    23881 tatattatct atggcctagc catggcagca ttttttgagg aaacggctcg tcttgttttc
    23941 ttcaaatggt tggagaaaaa gagaagtttg gaaaaggcag atgccttggc ctatggccta
    24001 gggcatggtg gcttggagtt gatttttcta ggccttacta gtttactcaa tctttacatc
    24061 gttctttcgg cagttcaaac tcagaatcca cagcacaggt tatgcaatta ctgtctgaaa
    24121 atatgttaaa aaccattcag tcactttcgg tctggcagat ttatttgctt ggttttgagc
    24181 gaatcttggc gcttggtttc caattacttt tgacagtttg ggtttaccaa gctgttcgcc
    24241 agaagaaatg gatttatctc ctagcagcct atggcttgca tgccttcttt gatctggcac
    24301 catctctttt ccaagtaggc tggttgacaa atccagtctt ggttgaagtg attctagcac
    24361 tggagctcgt tctggtcgcc tatggaacca aggaaatctt ttgtaaaaaa tcataaaaag
    24421 gggggaacct ctttttctta tgcaaaatcc aaacaaggta tttttatggt cgtcaaatgt
    24481 ctctaaaaat ggtataatgg aatgaatttt gtaaaaggaa gagtgacatg tctgtaagag
    24541 aaaaaatgct tgaaatctta gaaggaattg atatccgttt taaggaaccc ttgcatagct
    24601 atagttatac aaaagtaggt ggagaggctg attatttggt ctttccacga aatcgttttg
    24661 agttggctcg cgttgtgaaa tttgccaacc aagaaaatat cccttggatg gttcttggca
    24721 atgcaagcaa tatcatcgtt cgtgatggtg ggattcgtgg atttgtcatc ttgtgtgaca
    24781 agctcaataa cgtttctgtt gatggctata ccattgaagc agaagctggg gctaacttga
    24841 ttgaaacaac tcgcattgcc ctccgtcata gtttaactgg ctttgagttt gcttgtggta
    24901 ttccaggaag cgttggcggt gctgtcttta tgaatgcggg tgcctatggt ggcgagattg
    24961 ctcacatctt gcagtcttgt aaggtcttga ccaaggatgg agaaatcgaa accctgtctg
    25021 ctaaagactt ggcttttggt taccgccatt cagctattca ggagtctggt gcagttgtct
    25081 tgtcagttaa atttgcccta gctccaggaa cccatcaggt tatcaagcag gaaatggacc
    25141 gcttgacgca cctacgtgaa ctcaagcaac ctttggaata cccatcttgt ggctcggtct
    25201 ttaagcgtcc agtcgggcat tttgcaggtc agttaatttc agaagctggc ttgaaaggct
    25261 atcgtatcgg tggcgtagaa gtgtcagaaa agcatgcagg atttatgatc aatgtcgcag
    25321 atggaacggc caaagactac gaggacttga tccaatcggt tatcgaaaaa gtcaaggaac
    25381 actcaggtat tacgcttgaa agagaagtcc ggatcttggg tgaaagccta tcggtagcga
    25441 agatgtatgc aggtggtttt actccctgca agaggtagtg gggacctgac agagccccga
    25501 tcggttaatc tatgaaaaag aaggaattta tgccaattga aaaaaccaat tatcgaattc
    25561 aaaaacgtct ctaaagtttt tgaagacagc aacaccaagg ttctcaaaga catcaacttt
    25621 gagttggaag aagggaaatt ctacaccctt ctaggtgcat ctggttcggg gaaatcaact
    25681 atcctaaaca ttattgcagg tttactggat gcgacgacag gagatatcat gctagacggt
    25741 gttcgtatca atgatattcc aaccaacaag cgcgacgtac ataccgtctt ccaatcctat
    25801 gccttgttcc cacatatgaa tgtgtttgaa aatgttgcct ttccacttcg cttgcgtaaa
    25861 attgataaga aagaaattga gcagcgtgta gcggaagttc tcaagatggt tcagttggaa
    25921 ggttatgaaa aacgttccat ccgcaaactt tctggaggac aacgtcagcg tgtggccatc
    25981 gcccgtgcta tcatcaacca accccgtgtg gtcttgttgg acgagccttt atcagcgctg
    26041 gacttgaaat tgagaacaga catgcagtac gaattgcgtg aattacaaca acgattgggc
    26101 attacctttg tctttgtcac tcacgatcag gaagaagctc ttgccatgag tgactggatt
    26161 ttcgttatga atgatggcga gattgtccag tctggaaccc ctgtggacat ctacgatgag
    26221 ccaatcaacc actttgttgc cacttttatc ggggagtcaa acatcttgcc aggtaccatg
    26281 attgaggact acttggtcga atttaacggc aaacgctttg aagcggttga tggtgggatg
    26341 aagccaaatg aacctgttga ggtcgttatt cgtccagagg acttgcgcat tacccttcct
    26401 gaagaaggca aactccaagt taaggtcgac acccagctct tccgtggagt tcattatgaa
    26461 attatcgcct atgacgaact tggaaatgaa tggatgatcc actcaacccg taaggccatc
    26521 gtgggtgagg aaatcggtct ggactttgaa ccagaagaca tccacatcat gcgtctcaat
    26581 gaaaccgaag aagagttcga tgctcgtatc gaagaatacg tggaaatcga agagcaagaa
    26641 gcaggtctga tcaatgcgat cgaggaggaa agagatgaag aaaacaagct ctaaactctt
    26701 tgtagtgccc tacatgcttt ggattgccct ctttgtattg gcacccttgg tcttgatttt
    26761 cggacaatcc tttttcaaca ttgaaggcca gtttagttta gaaaattata aatcttactt
    26821 tgcgtcacaa aacttgacct acctcaaaat gagtttcaac tcagtgcttt atgcagggat
    26881 tgtgaccttt gtgaccttgc ttatcagcta tccaacagcc ctctttttga cccgtctcaa
    26941 gcaccgtcaa ctctggctca tgctgattat ccttcctacc tggatcaatt tgctccttaa
    27001 agcctatgct tttatcggga tttttggtca aaatggctct attaaccaat tcttggaatt
    27061 tatcggaatt ggttcacaac agttgctttt taccgatttt tcctttatct ttgtcgcaag
    27121 ctacatcgag ctccccttta tgattttgcc gattttcaat gtcttagacg atatggataa
    27181 taatctcatc aatgccagct atgaccttgg tgcaactaag tgggagacct tccgtcatgt
    27241 catcttccct ctatctatga acggtgtgcg aagtggggtt cagtcggtct ttatcccaag
    27301 tttgagtctc ttcatgctga cccgtttgat tggtgggaac cgcgttatca ccttggggac
    27361 ggctattgag cagaattttc taaccaatga caactatggt atgggttcaa ccatcggtgt
    27421 gattctcatc ctgaccatgt tcatcaccat gtgggtgact aaggaaagga gagaacgatg
    27481 aaaaaatttg ccaaccttta tctgggactg gtctttctgg tcctctacct gcctatcttt
    27541 tacttgattg gctatgcctt taatgctggt gatgatatga atagctttac aggttttagc
    27601 tggactcact ttgaaaccat gtttggagat gggagactca tgctgatttt ggctcagacc
    27661 tttttcttgg ccttcctatc agccttgata gcgaccatta tcgggacttt tggtgccatt
    27721 tacatctacc agtctcgtaa gaaataccaa gaagcctttc tatcactcaa taatatcctc
    27781 atggttgcgc ctgacgttat gattggtgct agcttcttga ttctctttac ccaactcaag
    27841 ttttcacttg gctttttgac cgttctatct agtcacgtgg ccttctccat tcctatcgtg
    27901 gtcttgatgg ttttgcctcg actcaaggaa atgaatggcg acatgattca tgcggcctat
    27961 gacttgggag ctagtcaatt tcagatgttt aaggaaatca tgcttcctta cctgactccg
    28021 tctatcattg caggttactt catggccttc acctattcgc tggatgattt tgccgtgacc
    28081 ttctttgtaa caggaaatgg cttttcaacc ctgtcagtcg agatttactc tcgtgcacgg
    28141 aaagggattt ccttagaaat caatgccctg tctgctctag tctttctctt tagtattatc
    28201 ctagttgtag gttattactt tatctctcgt gagaaggagg agcaagcatg aaaaaaatct
    28261 attcattttt agcaggaatt gcagcgatta tccttgtctt gtggggaatt gcgactcatt
    28321 tagatagtaa aatcaatagt cgagatagtc aaaaattggt tatctataac tggggagact
    28381 atatcgatcc tgaactcttg actcagttta cagaagaaac aggaattcaa gttcagtacg
    28441 agacttttga ctccaacgaa gccatgtaca ctaagataaa gcagggtgga acgacctacg
    28501 atattgccat tccaagtgaa tacatgatta acaagatgaa ggacgaagac ctcttggttc
    28561 cgcttgatta ttcaaaaatt gaaggaatcg aaaatatcgg accagagttt ctcaaccagt
    28621 cctttgaccc aggtaataaa ttctccatcc cttacttctg gggaacctta ggaattgtct
    28681 acaacgaaac catggtagat gaagcgcctg agcattggga tgacctttgg aagccggagt
    28741 ataagaattc tatcatgctc tttgatgggg cgcgtgaggt gctgggtctg gggctcaatt
    28801 ccctcggcta cagcctcaac tccaaggaat tgcagcagtt ggaagagaca gtggataagc
    28861 tctacaaact gactccaaat atcaaggcta tcgttgcgga cgagatgaag ggctatatga
    28921 ttcagaataa tgttgcaatc ggcgtgacct tctctggtga agccagccaa atgttagaaa
    28981 aaaatgaaaa tctacgttat gtggtaccga cagaggccag caatctttgg tttgacaata
    29041 tggtcattcc caaaacagtt aaaaaccaaa actcagccta tgcctttatc aactttatgt
    29101 tgaaacctga aaatgctctc caaaatgcgg agtatgtcgg ctattcaaca ccaaacctac
    29161 cagcgaagaa attgctccca gaggaaacaa aggaagataa ggccttctat cccgatgttg
    29221 aaaccatgaa acacctagaa gtttatgaga aatttgacca taaatggaca gggaaatata
    29281 gcgacctctt cctacagttt aaaatgtatc ggaagtagga gataaacgta agaagacgaa
    29341 tcagtcaagc tggttcgttt ttaaggaata gaagtcagtt tttagagccc tatctttttc
    29401 tattctagtt gtttatttgc ttatttgctt gcctagtagt atacttagcc tatactcttc
    29461 aaaccacgtc agcgttgcct tgccgtactc aagtacagct tgaggctagc ttcctagttt
    29521 gctttttgat ttttattgag tattaacctt acagaaagcg gcaacaaata atgaaaatgt
    29581 ctactttttt caaaaaaagt ttctggccaa cctttatgat tgttaaccaa actgttatac
    29641 tattccattt aaaggatggc ttggatcgac aatacctaac aactgagtcc atatattggg
    29701 tgataggcac ctttatattt ggaaatattc tagtagctgt gtttagtaat atgaaaattt
    29761 gggataaaaa gaaaaacggc agtaagaaaa aatatatcct gaaaaagtaa tcagagatgt
    29821 agggaattgg tctaattcaa cggagatcat ttccagttga cgcaagctta aaaaaacgtt
    29881 ataataagaa agttgagaat tgattttcac ttgtcttagt ccagagaaat ggcggtgctg
    29941 cgagccatct aagctaggaa gtcatgctac tcaatcatac aattgcataa gaacaagaga
    30001 atgacaagtt cattgaatga aggtggtacc gcggtttttc gcccttcgtg atatgagctt
    30061 gtcttttgat ttttggaggt gttgatgaaa acatttcttg tcaaacaaaa gtttcgtctt
    30121 ggaggcgaac gcttcgctat caaggatgac aggggagaaa ttgcctatca ggtggaggga
    30181 tcatttttta agattcccaa aacttttacc atctatgatg cggctggtga acaagtcagt
    30241 cagatcagta aagaaatctt gaccttgctt cctcgttttg agattcagct tcgggatggc
    30301 tcgagttttg tcattcgtaa gaagttgacc ttttggcgag ataagtatga gtttgataat
    30361 ctaggtcttc gtatcgaggg caatatctgg gatttgaatt tcaaattgct ggatgatcgc
    30421 gatcagttga ttgcggaaat taagaaggaa ctcttccatc tgacctctac ctataccgta
    30481 acggttcttg aagacgctta tgcagaccta gtcatttccc tctgtgtcgc gattgactat
    30541 gtggaaatac tggaaagcca atcacattaa acaagtgaat aaggagacaa tatgaaacaa
    30601 ctatctagtg cacaagtacg ccaaatgtgg cttgatttct gggcgaccaa aggtcactca
    30661 gtagaaccat cagtaagttt ggttcctgta aatgacccaa ctcttttgtg gatcaactct
    30721 ggggtagcaa cccttaagaa atactttgac gggaccatta tccctgaaaa tccacgtatt
    30781 accaatgccc aaaaggctat ccgtaccaac gacatcgaaa acgtagggaa gactgcgcgt
    30841 caccatacca tgtttgaaat gttggggaac ttctctatcg gggattactt ccgtgacgaa
    30901 gctatcactt gggcttatga gcttttgaca agccctgaat ggtttgattt ccctgctgaa
    30961 aaactttaca tgacctacta tccagacgat aaagattctt acaaccgctg gattgaagtg
    31021 ggagtggatc caagtcactt gattccaatt gaggacaact tctgggaaat cggtgcggga
    31081 ccttctggac cagatacaga aatcttcttt gaccgtgggg aagcctttga cccagaaaat
    31141 atcggtcttc gcctgcttgc agaagatatt gaaaacgacc gttatattga aatctggaac
    31201 atcgttttgt cacaatttaa cgcagaccct gctgttcctc gtagcgaata caaggaattg
    31261 ccacataaga acattgatac gggcgctggt ttggagcgtt tggtggccgt tatccaaggg
    31321 gctaagacca actttgaaac ggacctcttc atgccgatta tccgtgaagt cgagaaattg
    31381 tctggtaagg tttatgacca agatggcgac aacatgagct tcaaggtcat cgctgaccac
    31441 atccgttcac tttcatttgc catcggtgat ggtgcccttc caggaaatga gggtcgtggt
    31501 tatgtccttc gtcgtcttct ccgtcgtgct tctatgcatg gtcaaaaatt gggtatcaac
    31561 gagcctttcc tttacaaact cgttccaact gttggaaaaa tcatggaaag ctactaccca
    31621 gaagtgcttg agaaacgtga ctttattgag aaaatcgtta agagcgaaga agaatcattt
    31681 gcccgtaccc ttcactcagg tcaacacttt gcccaaggca ttgtagcaga cttgaaagaa
    31741 aaaggtcaat ctgttatcgc tggttcagat gtcttcaaac tctatgatac ttatgggttc
    31801 ccagttgaat tgactgaaga aatcgctgaa gaagctggta tgactgtaga ccgtgaaggt
    31861 tttgaagcag ccatgaaaga acaacaagaa cgcgcgcgtg cgtcagctgt caagggtggc
    31921 tcaatgggta tgcaaaatga aactcttcaa aacatcactg tagaaagtgc cttcaactac
    31981 aatgctagcc aattgtcttc taaattggta gctatcgtgg cggacaatgc agaagtagaa
    32041 gctgtttcag aaggaactgc ctctcttatc tttgcggaaa cgtcatttta tgctgaaatg
    32101 ggtggacagg tagctgacta cggacaaatc ttggatgagt caggtaaggt tgtggctact
    32161 gtgaccaatg ttcagaaagc cccaaatggt caagcccttc atacagttga agtccttgca
    32221 ccgcttgcct tgaaccaaga atataccttg gcaattgata gcaatcgccg tcaccgtgtc
    32281 atgaaaaacc acactgcgac tcatttgctt cacgctgccc ttcacaatat ccttggaaac
    32341 cacgcaacac aggcaggatc tcttaacgaa gttgaattcc ttcgctttga ctttacccac
    32401 ttccaagctg taactgctga agaattgcgt gcgattgaac agcaagtcaa cgaaaaaatc
    32461 tgggaagctc ttgaagttaa gacagttgaa acggatattg acactgctaa agaaatggga
    32521 gctatggccc tctttggtga gaaatacggc aaggaagttc gtgtcgtgac tatcggtgac
    32581 tactctattg aactttgtgg tggtactcat gttggcaaca cttctgagat tggtctcttc
    32641 aaaattgtca aagaagaagg aatcggttca ggaactcgcc gtatcttggc agtgactggt
    32701 aaggaagcct ttgaagccta tcgtgaacaa gaggatgctc ttaaagctgt cgcagcaacc
    32761 ttgaaagcac ctcaagtcaa ggaagtacct cacaaggtag aaggacttca agaacaactt
    32821 cgtcaacttc aaaaagaaaa tgctgagttg aaagaaaaag ccgcagctgc agccgcaggc
    32881 gatatcttca aagatgttaa ggaagtcaac ggtcatcgtt acattgctag tcaagtgtct
    32941 gtatccgatg ccggtgccct tcgtactttt gcagataact ggaaacaaaa agactactct
    33001 gatcttcttg tcctagttgc cgctatcggt gacaaagtca atgtccttgt agcaagcaag
    33061 acaaaagacc ttcatgcagg aaaccttgtc aaagaattag cactaatcat cgatggacgt
    33121 ggtggtggta aaccagacat ggccatggca ggaggaagca accaagctaa gatccaagaa
    33181 ttgttggatg cagtagcagg taaattgtaa tcaagtaaag atctatccat ttgggtaggt
    33241 ctttttgtga atacaaaaaa gccaaatccg cttggaccta gcttggttat tatgagctat
    33301 tagatggtat tgactgccca gacacttacg gatctagctg agacagggaa ttgtccataa
    33361 ccttcctcat caattgtaac ttgaccttgg tggttaccaa gtaaatctac aaaggtttga
    33421 ttagtccatt cttgaccgac aaacattgac ttgctgtttt cttggtcatt tgaaatcaag
    33481 actgcgattg gggattgatt ttcagcacct gaacgtaccc aaccgataca gttagcatgg
    33541 tcaaagtagt cattttgttc tccataggcc aaatcttttc ggatggctag gaggcggtca
    33601 aggatttctt tgaaatcttg ttgagcatac tggcctgaaa tcccatagta gtctccgtaa
    33661 aagacacatg gaaggccgtc ttggcgtaac aaaatgaggg cataggctgc tggcttgaac
    33721 cattcttcaa cggtagactc aagggcttgt cctcgttggg tatcgtggtt gtcgacaaaa
    33781 gtcacagact tgtcaggctt gagttcaacc aggctatctg tgaaaatgcc acgaaggtca
    33841 tagtttgcgc cagcttgact ggcttcaaag agattctggt ggagacgaac atcgacaagg
    33901 tcaaagtgtt cttccgtttt ttcgagatag tccagattgg cttccttgtc tgggttccaa
    33961 aattcaccaa aaacatagaa atcgtcaccg tatttttcct tcatatcgcg gatgaagttg
    34021 cgcataaaga aagagtcaat atgcttaacg gcatccaaac ggaaaccagc tacaccagtc
    34081 gtttccatga accaatcagc ccagtcatag atgttttgga tgacttcagg atgtttaaag
    34141 tctaggtcgg catacatgag gtagtcgtag tttccgtttt cgttatcgac caattcctcg
    34201 ttagcccagc ccttgttgtc cccttggatg agataaatcc cagacttacg gcgttttgca
    34261 tcgtagtctg taccggtgaa gtggtaccaa tgccagtgga agtcattgta ggtatcttgg
    34321 cgaccatcga aggtaaagct agtccagcca ttgatggtga agggttctcc aagtttaacc
    34381 gtacggtcta caggatccac ttcgataacc tgaaaggctt ccatgtgatc ggctgcagcc
    34441 ttgtgattga gaaccacatc ggccataggt tgaattccct gtgcttttag ggcttgaatg
    34501 gcttgaagat agtcttcttt gaaaccatac ttggtgcgga cagtcccttt ttggttaaac
    34561 tctcctaggt caaataagtc atagacacca tagccgacat ctttttcatt ggttgcctta
    34621 aaagctggtg gcatccagac gtggctaatc cccagatgag ctaggtgtgg agcatcttca
    34681 gccagacgcg tccagtgctg accgtcgtgg ggcagatacc attcaaagta ttgcatgagc
    34741 gtttgatttt gcatgatttt tcctcttact tgtcaatctt gttctttatt ctatcataaa
    34801 gtattggtta gcgcaaacgt ttgcgtaaga atagaaggaa actattgtat ctacttaaaa
    34861 taaagtgttg atttttttgt atcaaagtgc tagtataata gtatttaata tagataaaga
    34921 taggagtcat cccatgattg aatttcaaaa tgttagtaag ttgtatggtg ataaagaggc
    34981 cttgagtaat ctcaatttgc agattgaaaa tggagagatt atgggcttga ttggtcataa
    35041 tggggctgga aaatcgacca ccataaaatc cctagtcagt atcatttcac ccagcagtgg
    35101 tcgtattttg gtagatggtc aggagttatc ggaaaatcgc ttggcgatca aacgaaagat
    35161 tggctacgta gcagattcgc ctgacttatt tttacgttta acggccaatg aattttggga
    35221 attgattgct tcatcctatg atttgagcag ctctgacttg gaagctagtt tagctaggtt
    35281 attgaacgtt tttgattttg ctgaaaatcg ttatcaggtt attgaaaccc tttctcatgg
    35341 aatgcgtcag aaagtttttg tcatcggggc actcttgtct gatcctgata tttgggtctt
    35401 ggacgaaccc ttgactggtt tggatcccca ggctgccttt gatttgaagc aaatgatgaa
    35461 ggagcatgcg caaaaaggta agacagtttt gttttcaact catgtgctag aggtagctga
    35521 gcaagtctgt gatcggattg ctattttgaa aaaggggcat ttgatttatt gtggtaaggt
    35581 agaggacttg agaaaagaca acccagacca gtctttggaa agtatctacc ttagccttgc
    35641 tggtagaaaa gaggaggttt cagatgcgtc tcaaggtcat taaaaaatta gttgatatca
    35701 atatcctcta ttcatctaaa gaagctaatc tggctaacct acgaaagaag caagctaaaa
    35761 atactggaaa aaaagtaaat gtttccgcta gagtcctaag ttcttacatt ttttccagtc
    35821 tcttgatgct catctttttt agtactatag ccattcattt tccttttgag gaaatgcctg
    35881 tttattttag tttcgtggtt gctattttac tagtgattgc cttttcaact tctttaactg
    35941 cattttacaa tgtcttttat gagagtaagg acctggcctc ctatagtccc tatgctttta
    36001 aagaatcaga gattataatt gctaaaggac tgtctgtcct cttgccagct ctaactggaa
    36061 ttgtaccaat cctagcttat tttctagccc tctatattag tctagctcct tctctttggc
    36121 tgggtttgcc tttgatgcta ctgtccttga ccttattatt tgtctctgtt actttagtga
    36181 cggtagtggc agtacatttc ttggctcaga ctagggtctt cagaaagtat cagtctattt
    36241 tttcgaatgt gatgattggg ataggagttc tcataccttt aatatttatc ttctttcttc
    36301 agtcgacttt tggaagtatt gttgacaaag ttagagacat tccatttctc ctttatcctc
    36361 ttcatatctt ttacaaaata gcagtggagc ctttttcaat agaagccata ttgggtctgc
    36421 tcgcttggat aggactaact ctcttcctgc tttatctgac caaaaagaag gtccttcctc
    36481 gtttttatga cgtgatcctg cttaatagtg aggagaaggt caaaaaagaa cgtcgcagca
    36541 aggagagaat ttcaaccact aaaaagggat ttttccgcat ggttttacgc taccacctca
    36601 ccctcttggg acaggggact ggcgtggtta cagtgctttt tacaagtgct ttccttcctt
    36661 atctcatgat gatcggtctg atttccaaaa tccgagattc tcagatagtt ccagacattc
    36721 atcctccata ctggttaccc tttttttata gctctcttta tagcagttgt caataacaat
    36781 atcaccagcc tgccttcaat tgccttgtcc ttggagaggg aaaatgttga ttttctgaag
    36841 agtttaccct ttgactttgc tcgttatgtg aaagtgaaat tttggattat ctttgctgtt
    36901 cagtcctttt taccagttct gactttactt ggtctttctc tatatctagg cttgcccatc
    36961 ctttcgatga tttaccttat tgtggcatgg atccttgcca gtgtcatcct ttcttgtcac
    37021 cattatttta aggatgtgaa aaatctgtca accaattgga gtagcattac ggacctggtg
    37081 aatcgttcaa atggcatagt cgccatagtt ttattgttta ttttattgtt tatttatagt
    37141 gcaatcctga tggcccttgt aattgggagt atattcttgg ttcagtctct ctcccctatc
    37201 cttgccatca gcttgggagt aggagctctt atcctcctgc ttgctcttgc tatttttggc
    37261 tatcattatt acctgtcacg catattggca gaaatagaaa aaagatgagc tggttggtcg
    37321 cttgcttgat aaattcaatt cgacaaacgc ttttatagtt tgttagaatg tagttgtaaa
    37381 tgattaagat tggtaatcaa aaatatatag ggaggaatgt tttgaataag aaatataaca
    37441 tagttctatt tttgttgttt atagtttatt tattgggata tttttcaatt tcaaaaacgt
    37501 taattcctat aatgtgtgtg atccaagtat ttttgataga acatatattt agagttcgaa
    37561 atagaatgat acagataggt gaaattataa ttattgttgc ttctataata ttatttattg
    37621 atagtatatt gagtttgtaa caaaaggctt ctctataaaa tcaaattttc cagataccta
    37681 ttgaagtaga tttatttctt catctttctt ctactacctt tgtcactaaa tttgacagac
    37741 acatattgct gattcaacct ctctacctat aatctcacag ttaacctgag gctagtttca
    37801 tagtttgcta tttgattttc gttgataaaa agaaatgctc ctccaagacg gaagagcatt
    37861 ttttattgtg attcttacac atttacttcc tagttttgca ggaagtctag tataccattt
    37921 tttaaaagaa gagtaaaaaa gcaagggtag tttctttttt gagaattgtc taaaagtttg
    37981 atataatggt agttatgaat agaataagag tcagcaaaag ggttgaaaag aagcttgcta
    38041 aggggctagt tttactagaa gccagtgatc ttgagaatgt caatcttaag gatcaggaag
    38101 tagaggtgca gggtcaggaa ggaaactttc ttgggactgc ctacctttct cagcaaaaca
    38161 agggcttggg ctggtttgtc agcaaagaca aggtggcctt caatcaaact ttctttgaaa
    38221 cgttgtttag aaaagccaaa gaaaagagaa acgcctacta tcaagatgat ttgacaactg
    38281 cctttcgtct ctttaatcaa gagggagatg gctttggggg tctgacagtg gacctttatg
    38341 gcgactacgc cgtcttttct tggtataact cttatgttta tcagattcgt cagactatat
    38401 cagaagcctt tagacaggtt ttccctgagg ttttaggggc ttatgagaaa atccgcttta
    38461 agggttttga ctatgaatct gcccatgttt atggtcaaga agcacctgac tttttcactg
    38521 ttttagaaaa tggtgtcctg tatcaagtct ttatgaatga tggcttgatg acaggaattt
    38581 tcctagacca gcatgaggtt cgcggtagtt tagttgacgg cttggctatg ggtaaatcct
    38641 tgctcaatat gttttcctac acagcggctt tttcagtagc tgcggccatg ggaggagcta
    38701 gccagacaac ttctgttgat ctagccaaac gttcacgaga attgtctcaa gcgcattttc
    38761 aggcaaatgg gctcagcaca gacgagcatc gttttatagt catggatgtc tttgagtatt
    38821 tcaaatatgc caaacgcaaa gacttgacct acgatgtgat tgtcctagat ccgcctagct
    38881 ttgctcggaa taaaaaacaa actttctctg tggccaagga ttatcacaag ttgatttccc
    38941 agagtcttga gattttaaat ccgggaggga ttatcattgc cagtactaat gctgccaatg
    39001 tttcccgtca gaaatttaca gaacaaattg ataaaggctt tgcaggaaga agttaccaga
    39061 ttttaaacaa atatggtctt ccagcagatt ttgcctataa taaaaaagat gaaagtagta
    39121 attacctcaa ggtgattagt atgaaggtta gtaaatgaaa ttaatcgttt cagtaatgcc
    39181 aagaagttta gaggaggctc aggctctgga tgccacgagg tacctggatg ccgacatcat
    39241 tgaatggcgt gccgactatc tgcctaaaga agcgattttg caggtagctc cagccatttt
    39301 tgaaaaattc gcaggccgtg agttggtttt cacgctacga actcgctccg aaggtggaga
    39361 aatcgacctt tctccagaag agtatatcca tctaatcaag gaagttgcgc aattctatca
    39421 accagactat attgattttg agtactatag ctacaaggat gtttttgagg aaatgctgga
    39481 cttcccaaat cttgttttga gttaccataa tttccaagaa acacctgaga acatgatgga
    39541 aatcttgtca gagttgacga tcctaaatcc aaaacttgtt aaggttgcgg tgatggctca
    39601 cacggagcag gatgtcttag acttgatgaa ctatacacga ggctttaaaa ccctcaatcc
    39661 tgaacaggaa tatgtgacca tttctatggg taaggtgggc aaggtctctc gtatcactgc
    39721 ggatgtgact ggttcgagtt ggtcttttgc cagtctggat gaggttagtg cccctgggca
    39781 gatttctcta gctagcatga aaaaaatcag ggagattttg gatgaagctt gatggctata
    39841 cacgtttagc tgcagttgtt gccaatccta ttaagcattc tatttctccc ttcatccaca
    39901 atagagcctt tgaggcgaca gctaccaacg gtgcttatgt ggcttgggag attgaagcga
    39961 gtgacttggt agaaacagtg gccaatattc gtcgctacca gatgtttggc atcaatctgt
    40021 ccatgcccta taaggagcag gtgattcctt atttggataa gctgagcgat gaagcgcgct
    40081 tgattggtgc ggttaatacg gttgtcaatg agaatggcaa tttaattgga tataatacag
    40141 atggcaaggg attttttaag tgcttgcctt cttttacaat ttcaggtaaa aagatgaccc
    40201 tgctgggtgc aggtggtgcg gctaaatcaa tcttggcaca ggctattttg gatggcgtca
    40261 gtcagatttc ggtctttgtt cgttccgttt ctatggaaaa aacaagacct tacctagaca
    40321 agttacagga gcagacaggc tttaaagtgg atttgtgtgc tttagaatat gtttctgaac
    40381 tgcaagcaag gattgccgag tcggatttgc tagttaatgc caccagtgtg ggcatggatg
    40441 gccaattctc tcctgttcct gaaaacatag tcttaccaga aactctctta gttgcagata
    40501 tcatatacca accctttgaa acaccgtttt tgaaatgggc tagaagtcag ggcaatccag
    40561 cagtcaatgg tctgggaatg ttgctctatc aagctgcaga agcttttcaa ctgtggacag
    40621 gcaaggaaat gccgacagaa gagatttggc agtctttaac agaaaaatac caataaagaa
    40681 agggagactc tcctatgaaa atcagaatcg atattcctca tcatccttat gatattcaga
    40741 ttgaaaaagg ttgtatggcc caggctggtc agtggttgcg agaactctgg caaccgcaaa
    40801 aggtagtcat tgtgacagat aaccatgtag cctctctcta tgcagagaag gtcaagctca
    40861 gcctagaaga tgctggtttt caggtagctg tttttgattt cttagaaggt gaagaaagaa
    40921 agaatttaac tactgttcag aaagtctatg aatttctagt caagcaaggt ctgactcgta
    40981 gcgatggaat cgttgctctt ggtggtggcg ttgttgggga cctggctgga tttgtagcct
    41041 ctacctatat gcggggtatt cactttgttc agattccgac tagtttgaca gctcaggttg
    41101 attcttctat cggtggaaag acaggtgtta acacaccatt tgctaaaaat atggtgggga
    41161 cctttgccca accagatggg gttttgattg atccacttgt tcttgaaacc ctcggaaaaa
    41221 gagagttgat tgaagggatg ggtgaagtta tcaagtatgg cttgattgag gatccagaac
    41281 tgtgggctct cttgacggga ctgaatggtt ctgttgagag tattttggaa catgcagaga
    41341 ccttgattga acattcttgt caggtgaagc gcaagatggt ggttgaagat gagttggaca
    41401 atggtattcg tctttacctc aattttggcc acactattgg ccatgccatc gaagcgactg
    41461 ccggttatgg caaggtcatg catggagagg ctgttgccat gggaatggta cagatttcca
    41521 agattgctga ggaaaaaggc ctcatgccag ctggcattac ccaatctatc acagagatgt
    41581 gtcagaaatt cggcttgcct gttgactatg aaaattggga agttgacaag ctttatcagg
    41641 ctcttactca tgacaagaaa gcgcgtggca acaccttgaa attggtcttg gtgccagagc
    41701 ttggttcagc gaccattcat ccagtttctc tggaagagat gaaagactac ttggtaaaat
    41761 aaggagagtg tatgagatat ttaactgcag gagaatcaca cggcccccgt ctaacagcta
    41821 ttattgaggg aattccagct ggacttccat tgacagctga ggatatcaat gaggacctta
    41881 gacgccgtca gggtggctac ggtcgtggtg gtcgtatgaa gattgagaat gaccaggttg
    41941 tctttacttc gggcgttcgc cacgggaaga cgacaggggc gcctattact atgtatgtca
    42001 tcaataagga ccaccagaaa tggctggaca tcatgtctgc ggaggacatt gaagaccgcc
    42061 ttaaaagcaa gcggaaaatt actcatcctc gcccaggtca tgccgatttg gttgggggga
    42121 ttaagtaccg ttttgatgat ttgcgaaatt ctttggagcg ttcatcagct cgtgaaacca
    42181 ccatgcgggt ggcagttggt gcagtagcca aacgtctctt ggctgagctg gatatggaga
    42241 ttgccaacca tgtcgtggtc tttggtggca aggaaatcga tgttcctgaa aatctgacag
    42301 tcgctgaaat taagcaaaga gctgcccagt ctgaagtttc tattgtcaac caagaacgag
    42361 aacaggaaat caaggactat attgaccaaa tcaaacgtga tggtgatacc atcggtgggg
    42421 ttgtggagac agtcgtcgga ggcgttccag ttggtcttgg ttcctatgtc caatgggata
    42481 gaaaattgga tgcaagattg gctcaagctg ttgtctctat caatgccttt aaaggggtgg
    42541 aatttggtct tggctttgag gctggttatc gtaaaggcag ccaagttatg gatgaaattc
    42601 tctggtctaa agaagacggt tatactcgcc gtaccaataa tctaggtggt tttgaaggtg
    42661 gtatgactaa tgggcaaccc atcgttgttc gtggggtcat gaaacccatt cctactcttt
    42721 ataaacctct tatgagtgtg gatatcgaaa cccacgaacc ttacaaggca accgtggaga
    42781 gaagtgatcc gactgctctt ccagctgcag gaatggtcat ggaagcagtt gtagcaacgg
    42841 ttctggcgca agaaatcctc gaaaaattct catcagataa tcttgaggaa ctaaaagaag
    42901 cggtagccaa acaccgagac tatacaaaga actattaagg agttcctatg gcaaaaacaa
    42961 tctatatcgc aggtcttggg ttgattggag cctctatggc acttggtatc aaacgcgatc
    43021 atccagatta tgaaatttta ggttataatc gtagtcaagc ttcgagagat atcgccttga
    43081 aagaaggcat gattgaccgt gcaacggatg attttgctag ttttgctcct ttggcagatg
    43141 tcattatcct cagcttgcca atcaaacaaa ctattgcttt cattaaggag ttggccaatt
    43201 tggatttgcg agaaggcgtt attatttcag atgctggttc gaccaagtca accattgtgg
    43261 atgcggcgga gcagtatttg gctggcaagt ctgttcgctt tgtcggggcc catcccatgg
    43321 ctggtagtca caagacaggg gctgcttcgg cagatgtcaa tctttttgaa aatgcctatt
    43381 atatctttac accttcaagc ctgacaagtc aggacacgct taaggaaatg aaggatctgc
    43441 tttcaggtct tcatgctcgt tttatcgaga ttgatgccaa ggagcatgat cgtgtcactt
    43501 ctcagattag ccattttcct catattttgg cttctagtct catggagcag actgcggtct
    43561 atgctcaaga gcatgagatg gcaaggcgct ttgcggcagg tggttttcga gatatgaccc
    43621 gaattgcgga aagcgagcca ggaatgtgga cctccattct cttgtccaat agcgagacca
    43681 ttctggatag aattgaggat ttcaaggaac gtttggaagc gattggtcag gccattagta
    43741 agggagatga agagcaaatt tggaactttt ttaaccaagc gcgtgaacaa cgccagacca
    43801 tggaaatcca taagcgtggt ggtgtggata gctcttacga cctctatgtt gacgttcctg
    43861 atgaagaaga tgtcatcctg cggattttgg aactgctacg tgggacttcc ttggttaaca
    43921 tccacatcaa cgaggaaaat cgtgaggata ttcacggaat cctacaaatt tcatttaaaa
    43981 atgctcaaga cttggaaaga gccgagcatc tcataacaaa aaataccgac tatacagtcg
    44041 tcattaaata aggagaagaa catgtcaaat atttacgata gtgcaaacga cctcagtcgc
    44101 ggtctacgcg gattaccaga atacaaggct gttaaagcag ctaaagatgc gattgcagca
    44161 gatgctgagg caagcaaaat ctttacagaa tatcttgcct ttcaagagga aattcaaaaa
    44221 ctagcacaga caggtcaaat gccagatgcg tccttccaag ctaagatgga aggctttggt
    44281 aaacagattc aaggaaatag cctcttgtca gaattcttta ccaagcaaca acaattggcc
    44341 atttaccttt ctgacattga aaaaattgtt ttcgaaccag tttcagaatt gctgaaataa
    44401 gaaaagaact atcctaaagt caggaatttt taaggaattt ctggcttttt atgataaaat
    44461 aggtaaaagt attgcaagta tgaggtccag tatgaaacta aaaacaaaca ttcgccattt
    44521 acatggtagt atccgcgtcc caggtgacaa gtctatcagc caccgttcca ttatctttgg
    44581 aagtttggct gagggtgaga ccaaggttta tgatattctg cgaggtgaag acgttctttc
    44641 gaccatgcag gtttttcgtg accttggtgt tgaaattgag gataaagatg gggttattac
    44701 cgttcaaggt gtaggcatgg ctggcttaaa agcgccgcaa aatgccctta atatgggaaa
    44761 ttctggcacc tcgattcgcc tgatttcagg tgtccttgct ggtgcagatt tcgaagtaga
    44821 gatgtttgga gatgatagtc tttccaaacg tcctatggac cgtgtgaccc ttccactgaa
    44881 aaaaatgggc gtcagcatct cagggcaaac tgaacgagac ttgcctcccc ttcgcttaaa
    44941 agggacgaaa aacctaagac ctattcatta tgagttgcca attgcctctg cccaagtcaa
    45001 gtcagccttg atgtttgcag ccttacaagc taagggggag tcagttatta tcgaaaaaga
    45061 gtacacccgt aatcatactg aagatatgtt gcaacaattt ggtggtcatt taagtgtgga
    45121 tggtaagaaa atcacagtcc aagggccaca aaaattgaca ggacagaagg tggtcgtacc
    45181 aggagatatt tccagtgcag ccttttggtt agtcgcaggt ttgattgctc caaattctcg
    45241 tctagtgctg cagaatgtgg ggataaacga aactcgcacc ggtattattg atgtcattcg
    45301 tgccatgggt ggaaaattgg aaataactga aatcgatcca gtcgctaaat ctgcaacctt
    45361 gattgttgag tcttctgact tgaaaggaac agagatttgt ggcgctttga ttccacgttt
    45421 gattgatgaa ttgcctatta ttgccctact tgcgacccaa gcccaaggtg taacagttat
    45481 caaggatgct gaggagctca aggtcaagga aacagaccgt attcaggttg tggcagacgc
    45541 cttaaatagt atgggagcag atattactcc tacggcagat gggatgatta tcaaaggaaa
    45601 atcagctctt cacggtgcta gagtcaatac gtttggtgac caccgtatcg gcatgatgac
    45661 agctatcgca gccctattgg ttgcagatgg agaggtggag cttgaccgtg cagaagccat
    45721 caataccagc tatcctagtt tctttgatga tttggagagc ttgattcatg gctaaggtgt
    45781 tattagggtt tatgggggct ggaaaatcga ctattgcaag aggcttggac cctaattacc
    45841 ttgatatgga tgctctgatt gagaagcgcc taggtatgtc cattgcgaat tttttcgctg
    45901 aaaagggaga agcagccttt cgtcaggtag aatcagaagt cctagctgat ttattacaaa
    45961 gagaccaagt cgtgtcaact ggaggaggag tggttatttc tcagagaaat cgtgacttac
    46021 tcaagactaa tacagataac atctacctga aagcagattt tgaaaccctc tacctacgta
    46081 tcgcagctga taaggacaat cagcgaccgc tttttctaaa taatagcaag gaagaactag
    46141 tagctatttt tcaagaaaga caggcttggt atgaggaagt ggctagtcgg gttttggatg
    46201 tgaccaagct aagcccagag gaaattatag aggaactaag atgaaaattg cttatctagg
    46261 tcccaaagga tcattttcac accacgttgt gcagacagct tttcctcatg aggaattgca
    46321 ggcttttgcc aacattacag atgtcatcaa ggcttatgag caaggattag tggactattc
    46381 tgtggtgcca gttgaaaatt ctattgaggg tagtgttcat gaaaccttgg actatctttt
    46441 tcatcaggct cacatccaag cagtagcaga aatcgttcag cctattcatc agcagttgat
    46501 ggtggttcca ggccatacta agattgaaaa gattttttca catccacagg ccttggctca
    46561 aggaaagaaa ttcatcgatg aacaatatcc agaggctcaa atcgaggtaa cagctagtac
    46621 agcttatgcg gcccgtttta tttccgaaca tccagatcag ccctttgcag caattgcacc
    46681 tagaagttct gctgaagaat atggattgga actgattgcc gaggatattc aggaaatgga
    46741 agccaatttc acacgtttct ggcttctagg agctgaaaag cctagtattc ccttgcaagc
    46801 acaaactgaa aagatgagtt tggccttgac attacctgac aaccttccag gtgcacttta
    46861 taaggccctg tcgacctttg cttggcgagg aattgacttg acaaaaattg aaagtcgtcc
    46921 actcaagaca gcactgggtg aatacttttt cattatcgat gtggattata ccgataagga
    46981 cttggtccac tttgcccaaa aagaattaga agcgattgga atccagtata aaattctggg
    47041 tgcctatcct atttatccaa tatcagacca tggaaaggag agaagatgag taaagaaaat
    47101 cccttaagtc atcatgagca gttgcgttat gattatttgc taaaaaatat tcactatctc
    47161 aatgagagag aaaaaaatga gtttgtctat ttgcaagaaa agctaactct tgctagggga
    47221 aatagtagct ctagcttgga acaagaaaga gaagagcagg ttgacttacc aagctatgcg
    47281 aaccggagtc gctcacaatc caaatcacaa gcactctctt tccctccaaa aaagaaaaga
    47341 cggaagctcc gtcttaaacg aatttttatg gtgatttttt cacttttggt ctgtgtggct
    47401 ttggccatgg tattcatgtt tttgcgtggt taccaagatg ctagcgcaaa gaaaactgct
    47461 gatgcccggg cagctcaagt agaagtcttt aatggtcagg acactagaga tggagttaat
    47521 attttaatca tgggtactga tggtcgaatc ggccagaaca gtgttgagac acgaactgac
    47581 tctattatgg tattaaatgt cgggggctca gataagaaaa tgaagctagt cagtttcatg
    47641 cgtgataatt tggtctatat agatggttat agtcaagtga ttaacggtag aaaacagaca
    47701 gataacaagt taaacgtagc ctacgagtta ggagaacaag aggggcaaaa aggggcagaa
    47761 atggttcgcc aagtcttgaa agataatttt gacttggaca ttaagtacta cgccttggtt
    47821 gatttccagg cctttgccac agcgattgac acgcttttcc ctgatggggt gacgattgat
    47881 gctcaatttt caacattgaa tgggcgtccc ctaacagaag ctacagtcgg agatgattta
    47941 tacgctaccg agactgagtc tccaacccaa accattaaag tcggaaaaca gcagatgaat
    48001 ggctcgaccc tgctcaatta tgctcgtttc cgtgatgatg atgaggcgga ttacggccgt
    48061 acaaaaagac agcaacaagt tttaacagca attttagagc aaattaaaga tcccactaaa
    48121 cttttcactg gttctgaagc tcttggaaag gtttttgcta tgacctcaac caacgtaccc
    48181 tatactttcc tcctaacaaa cggtttatct gttttggatg gagcaaaaaa tggtattgaa
    48241 aaattgacga ttccagaact gggtgactgg gtagatgcct atgatgttta tggaggcttg
    48301 ggcttgctgg ttgatcaaaa caaatatcaa accaagctcg ctcaaatggg cttgagataa
    48361 gataatactc aatgaaaatc aaagtgcaaa ttaggaagct agccgcaggc tgctaaaaac
    48421 acagttttga ggttgtagat aagactgacg aagtcagtta cctataccta cggcaaggtg
    48481 aagctgacgt tgtttgaaga gattttcgaa gagtataaga cagaaaaatc aaagtttgat
    48541 agctatttgg atagcagtca ggctttgatt ttttacagtc tgcaatagat tttcacccct
    48601 tgtttgtggt ataatgaaac gatacgatag aaagaataat gaataatatg actgatttaa
    48661 aagcaattca ggctcgtagt ctggagatgg ctgaatattt tgtggccttt tgtaaagaac
    48721 atgatttgct ctgttatctc tgtggcggag gcgctattgg tgcccttcga aacaagggat
    48781 ttattccttg ggacgacgac ctagactttt ttatgcctcg taaagattat gagaaattag
    48841 cagaattatg gcctcgttat gcagatgaac gttatttctt gtcaaagagt cacaagaatt
    48901 ttgttgatcg taatcttttt attaccattc gtgacaagga aaccacctgt atcaagcctt
    48961 atcagcagga tttggatttg ccacatggtc tggccttgga tgttttgcct ttggattatt
    49021 atccgaaaaa tccagctgag cggaaaaaac aggttcgttg ggccttgatt tattcactct
    49081 tttgtgcgca aactattcca gaaaagcatg gtgctctcat gaaatgggga agtcgcattt
    49141 tactgggttt gactccaaaa tctctccgtt atcgcatctg gaaaaaagct gagaaagaaa
    49201 tgactaagta tgatttggct gattgtgatg gcattacaga attatgctca ggtcctggct
    49261 acatgagaaa caagtaccca atcacatctt ttgaagacaa tcttttcttg ccatttgaag
    49321 gaacagagat gcctattcca atcggctatg atgtctatct cagaactgct tttggggatt
    49381 atatgacgcc tccaccagca gacaagcagg taccgcatca tgatgctgtc atcgctgata
    49441 tggataagtc ttatacagaa tacaagggag aatatggtgg ctaagaaaaa aatcttattt
    49501 tttatgtggt ctttttctct tggaggtggt gcagagaaga ttctatcaac cattgtttca
    49561 aatctggatc cagaaaagta tgatattgat attcttgaaa tggagcactt tgacaaggga
    49621 tatgaatctg ttccaaagca tgtacgcatt ttaaaatccc ttcaagatta tcgccaaacc
    49681 agatggttac gagctttttt gtggagaatg agaatttatt ttccaagact gactcgtcgt
    49741 ttgcttgtaa aagatgatta tgatgttgaa gtttctttta ccattatgaa tccaccactg
    49801 ttgttctcta aaagaagaga agtcaagaag atatcttgga ttcatggaag tattgaagaa
    49861 cttcttaagg atagctctaa aagagaatca catagaagcc agttggatgc tgcgaataca
    49921 attgtaggga tttcaaaaaa gaccagcaat tctatcaagg aagtttatcc agattatgct
    49981 tctaaattac agacaatcta caatggatat gattttcaga ctattctaga aaaatctcaa
    50041 gagaagatcg atatcgagat tgctcctcaa agtatctgta ctatcggacg gattgaggaa
    50101 aataagggtt ctgaccgtgt agtggaagtg atacgattat tacaccaaga gggaaaaaac
    50161 tatcatctct attttatcgg ggctggtgat atggaagagg aactgaaaaa acgagtcaaa
    50221 gagtatgaga ttgaggacta tgtacatttc cttggttatc aaaaaaatcc ttatcagtat
    50281 ttatctcaga cgaaagttct cttgtctatg tctaaacaag aaggctttcc tggagtgtat
    50341 gtggaggcct tgagtctggg actccctttt atctctacgg acgttggagg ggctgaggaa
    50401 ttatcccaag aaggacgatt tggacaaatc attgagagca atcaagaggc agctcaggcg
    50461 attactaatt acatgacttc tgcctcaaac tttaatgtcg atgaggctag ccaattcatt
    50521 caacaattta caattacaaa acaaatcgaa caagtagaaa aactattaga ggagtagcat
    50581 ggaaactgca ttaattagtg tgattgtgcc agtctataat gtggcgcagt acctagaaaa
    50641 atcgatagct tccattcaga agcagaccta tcaaaatctg gaaattattc ttgttgatga
    50701 tggtgcaaca gatgaaagtg gtcgcttgtg tgattcaatc gctgaacaag atgacagggt
    50761 gtcagtgctt cataaaaaga acgaaggatt gtcgcaagca cgaaatgatg ggatgaagca
    50821 ggctcacggg gattatctga tttttattga ctcagatgat tatatccatc cagaaatgat
    50881 tcagagctta tatgagcaat tagttcaaga agatgcggat gtttcaagct gtggtgtcat
    50941 gaatgtctat gctaatgatg aaagcccaca gtcagccaat caggatgact attttgtctg
    51001 tgattctcaa acatttctaa aggaatacct cataggtgaa aaaatacctg ggacgatttg
    51061 caataagcta atcaagagac aaattgcaac tgccctatcc tttcctaagg ggttgattta
    51121 cgaagatgcc tattaccatt ttgatttaat caagttggcc aagaagtatg tggttaatac
    51181 taaaccctat tattactatt tccatagagg ggatagtatt acgaccaaac cctatgcaaa
    51241 gaaggattta gcctatattg atatctacca aaagttttat aatgaagttg tgaaaaacta
    51301 tcctgacttg aaagaggtcg cttttttcag attggcctat gctcacttct ttattctgga
    51361 taagatgttg ctagatgatc agtataaaca gtttgaagcc tattctcaga ttcatcgttt
    51421 tttaaaaggc tatgcttttg ctatttctag gaatccaatt ttccgtaagg ggagaagaat
    51481 tagtgctttg gccctattca taaatatttc cttataccga ttcttattac tgaaaaatat
    51541 tgaaaaatct aaaaaattac attagaacgg gggtgaccaa gtgattgatg ggaaacgatt
    51601 attatttagt ttgaccatag tcagttatac cttgacgcta gtaagtggaa ttgtgtatct
    51661 gtttaataat aataatgtta gcttactttc tactttattg ttcttgttgg ttagtagctt
    51721 aattgcttgt tggaatgata tcaagtatta cttaatccat tttattttct atttaaccat
    51781 ttttgtattt ctggtatcaa gaccgaccat tgattatttt agggatggtg ctttggatac
    51841 ctatcatcca atagcctatc gttttgcctt tatagttgtc atgatttcga ttctgggctt
    51901 gaccacagga ggcgtcctgg ctcgttactt catagctagg aagaaaataa aagtagcaaa
    51961 tataggaaat tctctaaaag aggtttatat caagcggtta cgctttgtat cactaggagt
    52021 ttttcttcta acctatcctt tctatttcat tcggttattt gaacggctct tgtatcgttt
    52081 gcagacttcc tactatgcct actatgcaaa ttttgaaagt aaactgcctt attttaccta
    52141 cattttgtct acctttacgg tctatgcaat gtgtatgtat ctggcaacca agccaaagaa
    52201 attgcaggcc acagcagtgc ttgtctcctt tattgcagct aatactattc atttggcaat
    52261 tgggacacga aatcccttta ttttaagtat tttatttgct tttgtttatt actttatgcg
    52321 ggagcaaact gaaaaaggaa aatggattgg gtttaaagaa aagttagcga tttttgtagg
    52381 ttctcctatt ctcatgttag cgatgggagt acttaattat gtacgggata atgtccaagt
    52441 ttcccataca ggtttctggg atatcttact tgactttatc tataaacaag gaactagttt
    52501 tggtgttctg gctcgaggtt ttctatttaa cagtagcctc ccttaccgag atttccgtaa
    52561 ttttactttt ggtcctgttc ttgattattt tgcaaggggg agtttgggag ccattttcgg
    52621 aggaaaagcc tttgaacata caaccaatag tgtggaacta gctattgata gtaatagtta
    52681 tgcccacaat ctatcctatc ttgtcttgaa caaggaatac ttgaaagggc atggtatcgg
    52741 aagtagttat atcatggagt tgtataccga ctatggtatg attggagtct ttctgcttag
    52801 tttcttactc ggcgtattat ttatagccat gctgcaagta gcctatcgct caaggacaat
    52861 cctatttgct ttatccctac tcatcttgaa taatctattc tttatgccaa gaagcagctt
    52921 ttcagaaagt ttcttcaatt tatttacaat gcaattctgg ggaattgttc ttgtgattat
    52981 atttgtagca aaaatgctta caaaggaaaa ctagtatcta ctaaacaaag gagaaaaaaa
    53041 tcatgtttga acattattca gtagctgatt tgtttgcaaa tctttataaa aaacgaaaag
    53101 caaatatttt agctctcatc gctttatttg ctctcattgc tgtaccattt acaattaaag
    53161 cagttaggaa taaaaacact gtcaaagata caacaagtta ttcaacttat cttatctata
    53221 aaatcactcc tccagaagat tcggccaaaa cgattttgaa tcatcaaatt ggtggttata
    53281 gtgattttta tgggaaattg attgatggta atttgaatgg agcttatctt ttcaatgatg
    53341 tagaacccag tgagttgaaa aaaattgcca gtgaattaga cacgacggaa acaaccttga
    53401 aaaattcaac gaatgactat tggtggaaaa aattgaccgt ctactatatg attgacgatg
    53461 caggggttgg tgtgaaaatt ttgacatcaa gtaaagatgc caatgacttg ttagagaaaa
    53521 aaattgatgg gttgattgag aaatttaaac atgcttatgc aaatgtgaaa attgaaaaac
    53581 tggaaaccat caactctaaa gaattgaacg caaatggtga aacagcgctt ggcttaaatg
    53641 tgaaaaatct gattcttcgt ttagttgtta ttggagtggt ttgtgtgatt ttggttgtga
    53701 tgggaaatgt gttagtttat ctctttaatc caacaatcaa tagagtaggt gatttttctc
    53761 agtatcaaat tgattttgta acagagatta caacaattgc taacctagca gatgttttgt
    53821 catacaaaaa tactggacag gaattgacca tcgttagctc aaataaagct atcctagata
    53881 aattgaaaca gagtcaagaa gctttaaaag gaatgcattt tgtagatttg caggatgtat
    53941 catctctttt ggaaagagat acagtccttc ttgttgaaga gtacggagtg actcgttata
    54001 agaaatttga gcaaagtctt caaattctca gaaacttaaa tcgttctatc ctcggtgtag
    54061 caacctttaa attataagta ttctgatgta taaggtcttc aaaatcggct aagagccgat
    54121 tttgaaggct ttttctatct gtctgcagaa attttctctt ggagtctcct atagaaagac
    54181 cctagggaaa atctatccgt atagaggagc cttcttttga taaaatcgta aaaatctagt
    54241 ataatagata gaactgaaag tatgaggtta ctagcaatga aaatgaaaca aattagtgat
    54301 acaactttaa aaatcacgat gtctttagag gatttgatgg atcgtggaat ggagattgct
    54361 gactttctcg ttcctcaaga aaaaacagaa gagttctttt atgctatctt ggatgagcta
    54421 gagatgcctg atagctttct ggatacaggc atgttgagct tccgtgtgac tccaaaacct
    54481 gataaggtag atgtctttgt gaccaagtca aagattgacc aaaatctaga ttttgaagac
    54541 ttatcggatt tgccagatat ggaagaattg gctcaaatgt ctccagatga atttatcaaa
    54601 accctggaaa aaagcatcgc agacaaaacc aaggatgata tcgaagccat tcaatctctt
    54661 gagcaagttg aagccaagga agaagagcaa gagcaggctg aacaagaagc tgagagtaag
    54721 aaagaacctt acatctacta catcctttct tttgctaagt tggctgactt ggtagctttt
    54781 gccaagacag tgacttttga aatggaaact tctgaactct acaaaatgaa cgagcgctat
    54841 tatttgacca ttttagtgga tattgaaaat catccaagcc catatccagc ttggctgttg
    54901 gcccgtatgc gcgagtttgc agacgatagt gatatcagtc gctcagtctt acaagagtat
    54961 ggtcaagtct tgatgagtca cgatgcagtg ctcaatctgc aaaaaatcgg ctaatccttt
    55021 ctggaaagct attttcagat tttaagaaga gcgaatcgtc tgattcgttt tttcttttta
    55081 tactgaaata gtgatttact ataataggaa ttttcacaaa attctgttat aatggctata
    55141 ttagaaaatt tcgaggagat aaagatgaca gttaaaattg ctttactagg atttggtacc
    55201 gttgcaagtg gtgtgccttt cctcctaaag gaaaatggag gaaaaatcaa tcaatcagca
    55261 cattcagata tcaaagttgc taaggtattg gtcaaggatg aagatgaaaa aaatcgcttg
    55321 cttgcagcag ggaatgactt taactttgta accaatgtgg atgatatttt atcagaccag
    55381 gatattacta tcgtagtgga attgatgggg cgtattgagc ctgctaaaac ctttatcact
    55441 cgtgccttgg aagctggaaa acacgttgtt actgctaaca aggacctttt agctgtccat
    55501 ggcgcagaat tgctagaaat cgctcaagct aacaaggtag cattttacta cgaagcagca
    55561 gttgctggtg ggattccaat tcttcgtact ttagcaaatt ccttggcttc tgataaaatt
    55621 acgcgcgtgc ttggagtagt caacggaact tccaacttca tggtgaccaa gatggtggaa
    55681 gaaggctggt cttacgatga tgctcttgcg gaagcacaac gtctaggatt tgcagaaagc
    55741 gatccgacga atgacgtaga tgggattgat gcagcctaca agatggttat tttgagccaa
    55801 tttgcctttg gcatgaagat tgcctttgat gatgtagccc acaagggaat acgcaatatc
    55861 acaccagaag acgtagctgt agctcaagag cttggttacg tagtgaaatt ggttggttct
    55921 attgaggaaa cttcttcagg tattgctgca gaagtgactc caaccttcct acctaaagcg
    55981 cacccacttg ctagtgtgaa tggcgtaatg aacgctgtct ttgtagaatc tatcggtatt
    56041 ggtgagtcta tgtactacgg accaggtgcg ggtcaaaaac caactgcaac aagtgttgta
    56101 gctgatattg tccgtatcgt tcgtcgtttg aatgatggta ccattggcaa agacttcaac
    56161 gaatatagcc gtgacttggt cttggcaaat cctgaagatg tcaaagcaaa ctactatttc
    56221 tcaatcttgg ctccagactc aaaaggtcag gtcttgaagt tggctgaaat cttcaatgct
    56281 caagatattt cctttaagca aatccttcaa gatggcaaag agggtgacaa ggcgcgtgtc
    56341 gttatcatca cacacaagat taataaagcc cagcttgaaa atgtctcagc tgaattgaag
    56401 aaggtttcag aattcgacct cttgaatacc ttcaaggtgc taggagaata agatgaagat
    56461 tattgtacct gcaaccagtg ccaatatcgg gccaggtttt gactcggtcg gtgtagctgt
    56521 aaccaagtat cttcaaattg aggtctgcga agaacgagat gagtggctga ttgaacacca
    56581 gattggcaaa tggattccac atgatgagcg taatctcttg ctcaaaatcg ctttgcaaat
    56641 tgtaccagac ttgcaaccaa gacgcttgaa aatgaccagt gatgtccctt tggcgcgcgg
    56701 tttgggttct tccagctcgg ttatcgttgc tgggattgaa ctagccaacc aactgggtca
    56761 actcaactta tcagaccatg aaaaattgca gttagcgacc aagattgaag ggcatcctga
    56821 caatgtggct ccagccattt atggtaatct cgttattgca agttctgttg aagggcaagt
    56881 ctctgctatc gtagcagact ttccagagtg tgattttcta gcttacattc caaactatga
    56941 attacgtact cgcgacagcc gtagtgtctt gcctaaaaaa ttgtcttata aggaagctgt
    57001 tgctgcaagt tctatcgcca atgtagcggt tgctgccttg ttggcaggag acatggtgac
    57061 cgctgggcaa gcaatcgagg gagatctctt ccatgagcgc tatcgtcagg acttggtaag
    57121 agaatttgcg atgattaagc aagtgaccaa agaaaatggg gcctatgcaa cctacctttc
    57181 tggtgctggg ccgacagtta tggttctggc ttctcatgac aagatgccaa caattaaggc
    57241 agaattggaa aagcaacctt tcaaaggaaa actgcatgac ttgagagttg atacccaagg
    57301 tgtccgtgta gaagcaaaat aaagaataga agataggatg gggaaactct tgaccagagg
    57361 gtttcatatc ctttttgtga aaagaagttt atactcaatg aaaatcaaag agcaaactag
    57421 gaagctagcc gcaggctgct caaaacagtg ttttgaggtt gtggatagaa ctgacgaagt
    57481 cagtaacata tatacggtaa ggtgacgctg acgtggtttg aagagatttt cgaagagtat
    57541 tagttaaaaa cgtgataaag gagaaataaa gatggcagaa atttatctag caggtggttg
    57601 tttttggggc ctagaggaat atttttcacg catttctgga gtgctagaaa ccagtgttgg
    57661 ctacgctaat ggtcaagtcg aaacgaccaa ttaccagttg atcaaggaaa cagaccatgc
    57721 agaaacggtc caagtgattt acgatgagaa ggaagtgtca ctcagagaga ttttacttta
    57781 ttatttccga gttatcgatc ctctatctat caatcaacaa gggaatgacc gtggtcgcca
    57841 atatcgaact gggatttatt atcaggatga agcagatttg ccagctatct acacagtggt
    57901 acaggagcag gaacgcatgc tgggtcgaaa gattgcagta gaagtggagc aattacgcca
    57961 ctacattctg gctgaagact accaccaaga ttatctcagg aagaatcctt caggttactg
    58021 tcatatcgat gtgaccgatg ctgataagcc attgattgat gcagcaaact atgaaaagcc
    58081 tagtcaagag gtgttgaagg ccagtctatc tgaagagtct tatcgtgtca cacaagaagc
    58141 tgctacagag gctccattta ccaatgccta tgaccaaacc tttgaagagg ggatttatgt
    58201 agatattacg acaggtgagc cactcttttt tgccaaggat aagtttgctt caggttgtgg
    58261 ttggccaagt tttagccgtc cgatttccaa agagttgatt cattattaca aggatctgag
    58321 ccatggaatg gagcgaattg aagttcgttc tcgttcaggc agtgctcact tgggtcatgt
    58381 tttcacagat ggaccgcggg agttaggcgg cctccgttac tgtatcaatt ctgcttcttt
    58441 acgctttgtg gccaaggatg agatggaaaa agcaggatat ggctatctat tgccttactt
    58501 aaacaaataa aacagagagt ggggcttccc actttcttca tttctagaat atgaatagaa
    58561 gggatttatg aaacacctat tatcttactt caaaccctac atcaaggaat caattttagc
    58621 ccccttgttc aagctgttag aagctgtttt tgagctcttg gttcccatgg tgattgctgg
    58681 gattgttgac caatctttac ctcagggaga tcaaggtcat ctctggatgc agattggcct
    58741 gctccttatc tttgcagtaa ttggcgtttt agtggccttg atagctcaat tttactcagc
    58801 aaaggcagca gtaggttttg ctaaggaatt gacaaacgat ctttatcgtc atattctttc
    58861 cttgcccaag gacagcagag accgtctgac aacttctagt ttggttactc gcttgacttc
    58921 ggatacctac cagattcaga ctggtatcaa tcaattcctg cgtctctttt tacgagcgcc
    58981 cattatcgtt tttggtgcca tttttatggc ttatcgaatc tcagctgagt tgactttctg
    59041 gttcttagtc atggttgcca ttttgaccat tgtcattgta gggttatctc gattggtcaa
    59101 tcctctctac agtagtctca gaaagaaaac ggaccaactg gttcaggaaa cgcgccagca
    59161 attgcaaggg atgcgggtta ttcgtgcttt tggtcaagaa aaacgagagt tacagatttt
    59221 tcaaaccctt aaccaagttt atgctagatt acaagaaaag acaggtttct tgtctagttt
    59281 attaatacct ctgacctatc tgattgtcaa tggaactctt ctcgttatta tctggcaagg
    59341 ctatatttca attcaaggag gagtactcag tcaaggtgct ctcattgctc ttatcaatta
    59401 cctcttacag attttggtgg aattggtcaa gctagccatg ctgatcaatt ccctcaacca
    59461 gtcctatatc tcagccaaga gaatcgagga ggtctttgcg gaatctcccg aaaacatcca
    59521 ttcagaatta gaacaaaagc aagttaccag tggtcgggtt ttacaagtcc aagaattgac
    59581 ttttacctat cctgatgcgg cccagccttc tctgagagac atttcctttg atatgactca
    59641 aggacaaatc cttggtatca ttggggggac tggttctggt aaatcaagct tggtgcaact
    59701 cttacttgga ctttatccag tagacaaggg gaacattgac ctttatcaaa atggacgtag
    59761 tcctcttaat ttggagcagt ggcggtcttg gattgcctat gtacctcaaa aggtcaaact
    59821 ctttaaggga actattcgtt ccaacttgac tttaggttta aatcaagaag tatctgacca
    59881 gaaactctgg caggccttgg agattgcgca agctaaggat tttgtcagtg aaaaggaagg
    59941 acttttggat gccctagttg aggcaggggg gcgaaatttc tcaggtggac aaaaacaaag
    60001 gttgtctatc gcccgagcag tcttgcgcca agctccgttt atcatcctag atgatgcaac
    60061 ctcggcactg gataccatta cagagtccaa gctcttgaaa gctattagag aaaattttcc
    60121 aaacacgagc ttaattttga tctctcaacg aacctcaact ttacagatgg cggaccagat
    60181 tctcctcttg gaaaaaggtg agttgctagc tgttggcaag cacgatgact tgatgaaatc
    60241 cagccaagtc tatcgtgaaa tcaatgcatc ccaacatgga aaggaggact agaatgaaac
    60301 gacaaactgt aaaccagacg ctcaaacgtt tagccgtaga tttagcaaac catcccttcc
    60361 tccttttcct agcctttcta ggaactattg cccaagttgg cttatcaatt tacctaccta
    60421 ttctgattgg gcaggtcatt gaccaagtcc tagtggctgg ttcatcacca gttttttggc
    60481 agatttttct ccagatgctc ttggtggtaa taggaaatac tctggtacaa tgggccaatc
    60541 ctctcctcta taatcgtcta atcttctctt ataccagaga tttgcgagag cgaatcatcc
    60601 ataagctcca tcgtttaccg attgcttttg tagataggca aggtagtgga gagatggtta
    60661 gtcgtgtaac cacggacatc gaacagttgg cagctggctt gaccatgatt tttaaccaat
    60721 ttttcattgg tgttttgatg attctggtta gtattctagc catgctccaa attcatctcc
    60781 tcatgactct cttagtcttg ctgttgacgc cactgtccat ggtgatttca cgctttattg
    60841 ccaagagatc ctatcatctc ttccagaagc aaacagagac gaggggaatt cagactcagt
    60901 tgattgaaga atcgcttagc cagcagacta taatccagtc cttcaatgct caaacagaat
    60961 ttatccaaag attgcgtgag gctcatgaca actactcagg ctattctcag tcagccatct
    61021 tttattcttc aacggtcaat ccttcgactc gctttgtaaa tgcactcatt tatgcccttt
    61081 tagctggagt aggagcttat cgtatcatga tgggttcaac cttgaccgtc ggtcgtttag
    61141 tgactttttt gaactatgtt cagcaataca ccaagccctt taatgatatt tcttcagtgc
    61201 tagctgagtt gcaaagtgct ctggcttgcg tagagcgtat ctatggagtc ttagatagcc
    61261 ctgaagtggc tgaaacaggt aaggaagtct tgaccagtga ccaagttaag ggagctattt
    61321 cctttaaaca tgtctctttt ggctaccatc ctgaaaaaat tttgattaag gacttgtcta
    61381 tcgatattcc agctggtagt aagatagcca tcgttggtcc gacaggtgct ggaaaatcaa
    61441 ctcttatcaa tctccttatg cgtttttatc ccattagctc gggagatatc ttgctggatg
    61501 ggcaatccat ttatgattat acacgagcat cattgagaca gcagtttggt atggtgcttc
    61561 aagaaacctg gctcacacaa gggaccattc atgataatat tgcctttggc aatcctgaag
    61621 ccagtcgaga gcaagtaatt gctgctgcca aagcagctaa tgcagacttt ttcatccaac
    61681 agtttccaca gggatacgat accaagttgg aaaatgctgg agaatctctc tctgtcggcc
    61741 aagctcagct cttgaccata gcccgagtct ttctggctat tccaaagatt cttatcttag
    61801 acgaggcaac ttcttccatt gatacacgga cagaagtgct ggtacaggat gcctttgcaa
    61861 aactcatgaa gggccgcaca agcttcatca ttgctcaccg tttgtcaacc attcaggatg
    61921 cggatttaat tcttgtctta gtagatggtg atattgttga atatggtaac catcaagaac
    61981 tcatggatag aaagggtaag tattaccaaa tgcaaaaagc tgcggctttt agttctgaat
    62041 aagccattct cttttgaaag tttatggacg aaaaaagttg ccttcgagtg acttttttgt
    62101 tacaatagct agaaaaattg ttcactgtaa tactcaatga aaatcaaaga gcaaactagg
    62161 aagctagccg taggttgctc aaaacagtgt tttgaggttg cagatagaac tgacgaagtc
    62221 agtaaccaca cctacggcaa agtgaatttg aagtggtttg aagagagtac aacttgtctt
    62281 ttagaaaagg agcctataat gaaagtcttt cagcatgtaa atatcgtgac ttgtgatcaa
    62341 gatttccatg tttatcttga tggaatctta gcagtcaagg attctcaaat cgtctatgtc
    62401 ggtcaagata agccagcgtt tttagaacaa gctgagcaga ttatagacta tcagggagct
    62461 tggattatgc ctggtttggt caattgtcac acccattctg caatgacagg tctgagaggg
    62521 atccgagatg acagcaatct ccatgaatgg ctcaatgact atatctggcc agcagaatct
    62581 gagtttactc ccgacatgac taccaatgcg gtcaaagaag ccctaacaga gatgctccag
    62641 tcaggaacaa caacctttaa cgatatgtat aatcccaatg gtgtggatat ccagcaaatt
    62701 tatcaggtgg tgaaaacttc caagatgcgt tgttattttt ctccgactct cttttcttca
    62761 gagacagaaa caactgctga gactataagc agaactcgat ccatcataga cgaaatctta
    62821 aaatataaaa atccaaattt caaggttatg gtagcacctc attctccgta tagctgcagt
    62881 agagacttgc tggaagcgag tttggaaatg gcaaaagagc taaatattcc gctccatgtc
    62941 catgtggcgg agaccaagga ggagtcagga attatcctca aacggtacgg caaacgcccc
    63001 cttgcttttc ttgaagaact gggttattta gatcatccgt ccgtatttgc tcacggggtc
    63061 gaattaaacg agagagaaat tgaactcttg gcatcttctc aagtggctat cgcccacaat
    63121 cctatcagta acctcaaact ggcatcagga attgctccaa ttatccagct ccaaaaagcg
    63181 ggagtagtag tcggaattgc gactgactcg gttgcttcca ataacaatct agatatgttt
    63241 gaggaaggaa ggactgcagc tcttcttcag aagatgaaaa gtggggatgc cagccagttt
    63301 ccaatcgaaa cagctctcaa ggtactgaca atcgaagggg ctaaggtcct tggaatggaa
    63361 aatcagatag gaagtctgga agtcggcaag caagcagatt ttctggtcat tcaaccacaa
    63421 gggaaaattc atctccaacc tcaggaaaat atgctgtctc acctggttta tgcagttaaa
    63481 tctagtgatg tagatgatgt ttatatcgcc ggagaacagg ttgttaagca aggtcaagtc
    63541 ctgacagtag aactttaaaa gaaaaatcac gaaaaatttt aaaaaaagtt tgcaaaaatc
    63601 ttgcattctt tttttgacta tgctatactt atatacggtt taaaaaaact gcctaagaca
    63661 gtaggggagc tcgactcata aatatcctac cgaggacaaa acgtatcatg taaaaagaag
    63721 cgtattgtac tttcgtgtct aggtttgggc gcgtttttct ttttgaaaaa ttccccaagc
    63781 aaaataatta cggaggtgaa cacactaatg agtgaagcaa ttattgctaa aaaagcggaa
    63841 ctagttgacg tagtagctga aaaaatgaaa gctgctgcat ctatcgtcgt tgtagacgct
    63901 cgtggtttga cagttgagca agatacagtt cttcgtcgtg agcttcgtgg aagcgaagtt
    63961 gagtataaag ttattaaaaa ctcaatcttg cgtcgtgcag ctgaaaaagc tggtcttgaa
    64021 gatcttgcat ctgtatttgt tggaccatct gcagtagcat tttctaatga agatgttatc
    64081 gcaccagcga aaatcttgaa cgacttttct aaaaacgctg aagcacttga aattaaaggt
    64141 ggtgcaatcg aaggcgctgt cgcatctaaa gaagagattc ttgcacttgc aactcttcca
    64201 aaccgcgaag gacttctttc tatgctcctt tctgtacttc aagcgccagt gcgcaacgtt
    64261 gctcttgcag tcaaagcggt tgcagaaagc aaagaagacg cggcttaatc ttaagctaca
    64321 cagcgtagcc tagctacgaa aaaaactatt ataaaattta aaacttattt ggaggaaata
    64381 acaatggcat tgaacattga aaacattatt gctgaaatta aagaagcttc aatccttgaa
    64441 ttgaacgacc ttgtaaaagc tatcgaagaa gaatttggtg taactgcagc tgctcctgta
    64501 gctgttgctg cagctgatgc agctgatgct ggtgctgcta aagattcatt cgacgttgaa
    64561 ttgacatctg caggcgacaa aaaagttggc gttatcaaag ttgtacgtga aatcactggt
    64621 cttggtctta aagaagctaa agaacttgtt gacggtgcac cagcacttgt taaagaaggc
    64681 gttgcaactg cagaagctga agaaatcaaa gctaaattgg aagaagctgg agcttcagtt
    64741 actcttaaat aatagagtat cgcaatttga ttgcggaatc cctatttacc agtctttgag
    64801 agcgataagc gattgataga aactgataaa ttgatttggt ttcctgtcaa aaattctttg
    64861 gcaggatttt tgttttaata aactttcggg ggtagacact agattgtcta cccctttttt
    64921 tgtgtttcgg aggtaattat gcaaaaggaa ggacagtcat cacgtcaatt catgaagagt
    64981 catctcatga ctatcatggg agttgatatt gtaaaagcaa ctcagttagt tgatgaaatg
    65041 gaacaagtag gtttaatccg atttgatgaa tttggaaatg ttggaatttt agtcttggag
    65101 ggacaataat gaagcgtatt accgctaatc aatatcagac atcagagcgt tattataagc
    65161 tccccaaact tttatttgag agtgaacggt ataagaatat gaaaccggag gttaaggtgg
    65221 tttactcagt tttaaaagat cggttggagt tgtctttgag caaaggttgg attgatgagg
    65281 atgggactat ttatttgatt tattccaatt caaatttgat ggcactttta ggctgttcaa
    65341 agtcaaaatt actctccatg tgagtttgaa gtgacatttt tagatgatta ccataaaaaa
    65401 cataactacc cactatttta cgaatcctat cttcaaaacg ttatggaatt ccttgaaagt
    65461 caagacataa agaatggggt tgatgccttt gtagatgatc atcaaaatct cgtttttgtt
    65521 ttatatggac aaggctatcg agccgaggga aaagagggaa tacttacaac ccaagtaact
    65581 gtaaaagctt atgatgaaga caagaaaccg attaacttcg caaatttatt agattcctta
    65641 atcgtgtcag aatatcaaat ggaaccgaat ctttgggagg tctcctatga ttgatctcta
    65701 tctaagtaaa aatagccgaa gaaatcaact tcttttagac ttcttccaaa actatggcat
    65761 cgaggtatct tgtcattcag tttctgaaat gacaaaggac aaattaattg agatgatgag
    65821 ctattcttca gattgttttg agtttttatc tccaaattta ttacgtttta agaatcgaga
    65881 taacctaaaa ttaacagatt tcatcgaaat gatattaaaa aatcctgaac taaccatcag
    65941 acttcctctt gcggtttcaa ataagcgagt ttatccaagt ctgaatttgg aagaggctag
    66001 agctctattg ccaagagata cgaaacaatt gatttacatg gcgcaaacac attatttatc
    66061 taactaaagg agaagcaata tggctgaacg attttgggag aacttgtcca ttattttggc
    66121 tgaaagaaat atcagctgga ttgagctaac cagaaaaatg tttgcgggag agtttcacta
    66181 tccaagtgaa ttgaatcgtt tgtatcaaaa gattcgtcac tacaagatgg aacaacgaat
    66241 gcctcaaagt ccatgggtag aaaggattgt gcaggtatta gatttagatt atgaagattt
    66301 atttcggagg taactatgaa aagaataatt ccagtttata tattccaaca agtaaatgtc
    66361 ctattggtat ctctatactt actgaaattt ctttgtatcg gtgagttaac tatactacag
    66421 attctatatt gtgcgtcact catttctttt ttatggatgt atgcccaacg taaacaagcg
    66481 cataaggtca atatgaaatc aaggataaaa tggattggta ttggattagc cagtctactg
    66541 attataagtc tatgttttag tctaatccat gcgcaagaaa gcacgaatca agcaaactta
    66601 attgggcttc aatatcaagt tccttggttt tcatttttat tgttcttaat caatgcgagt
    66661 atggttgaag aatttctgta tagagaaatt ttatggaact tggttagaaa attagatatt
    66721 cgagttgctt tgacaagtgt tttatttgcc ttagcacatc atccaggaac cattatagct
    66781 tggtgtttgt atgtatcgct ggggatgttt ttagggcttg tacgctacaa attggactta
    66841 tggggcagta tggggctaca tttggtgtgg aacctactag tttatagttt gctgcttttt
    66901 taaaataggt aacctgattt ttaggtaact tctaaaacta acttccagtt ttgggagaga
    66961 gatggaagtt actttgaaaa gttacggaaa cattattttc tatgtgacaa cattgtatca
    67021 ttgcttgcat tttactgctg gagagagtat aatgaatgtg gataaagcac ttaatcccaa
    67081 aaatttaaat aggaggagtt agctatggca gaagaagtat taaatcttta attagtatct
    67141 gttcaagttg acgaaacaga tgaagttgat ggaatgcgat ttagtacatt cagtacaaac
    67201 cgttgcggta actggagtgc ttttagttgg gaaaattgtt aattcattta aattgtaaac
    67261 tttagagatt ctctggagtt atggatctcg ttccaatatg tgcacgttgg aatgttagtg
    67321 cttatatggg gggaacagaa tcctctcttg attgaagaca agctagtcat taggctagtt
    67381 tgtctttttg tcaactgtag tgggttgata taatagtatt agtgagtggg ataaaagttt
    67441 catttagttt attcagtaca aatttaacgg gtcaagattt atatactggt ggtgtttttg
    67501 gggctgagag aagtatcttg attttatgtg tggtttttat acttacagtt gttctgctcc
    67561 aaagagcttg tagagaagaa ttagctcata aaggagattg attattttga tatcaaaaaa
    67621 atgcacagga taacctgatg cattttttta gcgacaatgc ttgctacttc cttctgtcga
    67681 atttagacaa ttttaaataa aagaatgaaa tattccctac tgtattttta gacgaagaac
    67741 gttagttaat aatactcaaa tttatttcaa actctttgat tagtatgaat ttagctctac
    67801 agaaaaataa aaaatgtgat aaaaatttca actactctta tctataataa agctacctgt
    67861 tctttgaaaa ttgaatccac tccgtcttga ttagcgtgcc tgtgtaagta gggactgaga
    67921 gtatttccct gtgaagggca actggcacaa gacgtgtgtg agaattttct aacagacacg
    67981 gagtttatcg tttccagact caaacgatgc gacaaactag ataaaggagt taatcatgaa
    68041 ggtagtaaac ttgtatgatt tgaaacaaat gggaaataaa ggtggttgta ccatccaatt
    68101 gattcatcac tttccttttg gtatgggctt aggacatctc aaaaaggact acattgaatt
    68161 taaacgtgtt ggtatctttg atgggaaagc agtagaagtt actcttcgag aaccttattc
    68221 gagagatata ctgcaggttg tcaagtcgat taagcaacgt cagaaattga tagcttatcg
    68281 ttataaagaa ggaaagctgc tatttgttaa gaaggaggtc tgagatgtcc tctgaacaac
    68341 aggaacgaat ggcagttcaa tatgctgagc gtagtctttt atttactgta aaaggtcttt
    68401 taaagatact agaatggtct agatgtcagg ctttagaaca ggattccgcc tataagatag
    68461 gggtgtagaa attagaagaa ttgctacaat ctccctatgc gattgatacg attaatctga
    68521 aaaaagattt tttagaaaaa ccaattgata tagagaaatt taaagctttt ttagaaaaag
    68581 aagagattcc tttagccatc gcttggcaag gggattctct gcatttctac acgaaagacc
    68641 gttcgattct agacaatcat ttagaccatc tgttagaaaa aatggtgaat gatcctgaga
    68701 aattatctga tttttccatg gataagtcat tagacgatac aattgatgag gctaaatccc
    68761 aaattacctt taaataatag agtatcgcaa tttgattgcg gaactcttgt ttaatgagag
    68821 ttgagataat ataaaggcga taataattgg gagaataatt atattccccg ccaaacccca
    68881 ctaagttttt atcttggtgg ggtttcttgg tacgacttac ccttattaaa attattatgt
    68941 agtttttttg aatttagcat catcaagatt ctgattgttt tgatattgac ttttcattta
    69001 tttctaatac tcatctgttt tcaaaaagca ttctagtcca tctccgatta acgatggact
    69061 ttatcacctc cttctccagt ccttgtatga catcttgaag ttgattcatg acatcttcca
    69121 aagttcgaaa ggccttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa
    69181 tgggttcatc tctggtgtgt atggaggaat aaaggtaaaa ccaatattag tcggaatctt
    69241 taaggtactt gatttatgcc atatagcatt gtccataacg agtaaaagat aatcatctgg
    69301 ataagcttgt gaaagctctt ctaaaaagga gttcatccac tcagtattac atccaccagc
    69361 tattaagaaa aatgattcgc ctgtatgggc atcaacagct ccataacaat agtgaaattc
    69421 tcgtatatag tgactatgga catgtggacc tactcctatt ggagaccaac aagatcccag
    69481 tttactgatt ctaccgaaac cagcctcatc ttggtacatc aagcgaacct tatgaaaacg
    69541 tctactggtt ttaaatcgct ttcttgtctt cttgaattga gattttattt ttagacgcga
    69601 caatggtttg agcgtctgct ttcttaggat gttctggacg tggcataata tttcgccagc
    69661 catggcgctt caacagttga tagaaggcat cacgtgtgta ggaacgacct aactcctttt
    69721 tataagcctg aaataaggca tcaattgtaa caaattctcc tgcctctgta gccttcaaat
    69781 ggcgggcaag aaagactttc tcttcctcaa ctgtcatata tgcatggtta cgaccaccac
    69841 gtgtttcttg aaggagagag tcgagtccga actcctcata tttttttaca ttttgctaaa
    69901 tcgttgttta attacagtct aaaagctcta taatctcttt ataagatttg cccatcagac
    69961 gaaatagaac gatttgaagg cgtttatgat atttagctgt acgagagtct tttaaaagtg
    70021 ttttgatggt ttggatttct tctttagttg attttatatt actattatat aatacttttt
    70081 tattttagtc tagtataaat agcgagaaat atctatccta tcttctagaa tgtcttccaa
    70141 acgagaaaac tctcgtaaac aaagaggttt tagaggccta tttaccgtgg gactaaagtt
    70201 gtacaagaaa agtgcaaata agaaatctcc agattaggaa ctatccgtga gttctctagt
    70261 ctggagattt ttcaatagac ttcgttattg gacggttacc aagttactca aagtacagat
    70321 ttgaagctgc agataagatt gacgaaatca ctttaatact aaatgaaaat caaaaagcaa
    70381 actaagaagc tagcctcagg ctgtacttga gtacggtaag gcgacgctga cgtgatttga
    70441 agagattttc gaagagtata aaacactgtt ttgaggtggt ggataaatcg gctgggtaaa
    70501 aactcaatct caggagaaaa tgaagtaaat ctccccacaa ctatagaaaa agatttgatt
    70561 ctgctcctca cacaataaaa tctttttctt ttattaaaaa cgaatcgttt cacgtgtttt
    70621 ctcatatgag gtaacaaagc gattggttac accaggctct gccacttcca atgcttgaga
    70681 aatcttgtca aatgaagcgt gataatcaaa ttctttttca aaaatatcta aagcttcgtt
    70741 aaatgcttct tgaatgcgtt catcaaatga gcgatagcgg ttagaatatt gcaagagttg
    70801 ctctgtcaaa gttgcatatt gtacaatatt ataagtttcc gtttctaaag cttccatatc
    70861 attcgttgca atttcaagaa ctcgggtaac agattcaatg ttaatcattt tttgttctaa
    70921 ctcaaccatt aaatcctcgg tattattgct tgccgtaaag aataacttca agaaagtttg
    70981 tggaatacct ggcagattgc gtttttccat gtatcgcttg atagtatgga gacgattgac
    71041 ataaacattg gccttttgac gtgcattaat atcatctttc tcaatttgtg tcaggcgctc
    71101 actaactgaa atttgctcat cttcaatatc ttttagttga gtttgtaaat cctcaagatt
    71161 ttcttcaaga actgaataag cttgggttgg ttcttcttga tttgaagtta cctcaacaat
    71221 agctgcctca aaactctcta attctgtctg aatacgacga acatggcttg cagctgtctc
    71281 aggaagtaaa taggtcttgt tcaaacgtgc aatatcttct cccaataaag tattattctc
    71341 tttcatatgt tgaaggtaag ttggaagagt tgcaagtaga ttttccacta ctttctgagc
    71401 agcaatttct cgagtaaaaa tatcatacaa ggcattgatt tcctcttgtg cctgtccatt
    71461 ctcatattcg gcattatcca attccaactg acgaatattc tcttggtttt tcttgaatgc
    71521 ttcataaagc aagtggaaac gcgcttcaat atccgtttca acaaaatgat aattagcatc
    71581 aattagttta cgataaccgg cttccaaatc ctgtaattga tctggcaatt ctgtagaaag
    71641 cgtcgtaacc aaggctggaa cacgatccac aatatgactt aaggccaaaa tgtgattttc
    71701 tgtattatcc aaaatcactg cggcttccac agggtcaccc gatgaattca aggttacaaa
    71761 ttgtgaaaat tcagattgga tattttctaa ttgtttttca atttcatcca aggcttgacc
    71821 atactgttct gaattttcag caactctatg ctgaagttcc tcaaataaat ccgaagcatg
    71881 aagaacacga ccactatttt tagattcttg cttctctaag tctgccaaag cattgcgaat
    71941 tgccgcaata tcttcttcaa tcaaagtaat ttgactctca atttggtcaa tttgatgact
    72001 ggccttgaga aaacgaaatg aatggttata gccttctgct tcaaagagat tattttcaat
    72061 atcggcaaaa gagttgagag ataaatcgac ccatttttga ttccattcac ggaaagccac
    72121 ttgactttgt ccaatcaagt gcatattttt tacagcttct acttcatcat ttactggaag
    72181 attgtatagt tcttcttttc tttcttctag cgcctctaat ctcccctcgt ttcgcttacg
    72241 tagaaagatt gccactacat aagccagaac taaaatgact gcaattgcaa ccattaaata
    72301 aattagttgt ccattagaca tatcaaactc cttttttact tgaaacaatc gtaacaatta
    72361 tatcatattt tttagaccaa gggaactact tctccctatt ttttagacat caagtgtact
    72421 atagacagca ttttcttcga taaactcacg acgaggctct actcgatccc ccatcaacat
    72481 atcaaagatt ttatctgctt ctgcagcatc atctacagaa actctagcca tcaagcgatg
    72541 ttcgggatcc atggttgttt cccacagctg atgatcgtcc atttcaccta gccccttata
    72601 acgctgaata gtcggtttgg tacgaccttc actataacgg gctaaagctt cttggagttt
    72661 gatttcttga tctgcacccg gttggatata ttctttaatc tcgcttccaa ccttgacacc
    72721 atagattggt ggttgggcaa tataaacata accagcttct aggattggtt tcatataacg
    72781 ataaatcaag gttaaaagaa gggtacgaat gtgggctcca tcgacatcgg catcggtcat
    72841 caaaacgagt ttttggtaac gggctttcga aacatcaaat tctgcgccaa atcctgttcc
    72901 catggctgtg aaaagactac gaatttcttc gttagctaga atcttatcca tacttgcttt
    72961 ttcaacgttc aaaatcttac cgcgaattgg aaggatagcc tgaaactcac ggttacgacc
    73021 agatttggct gatccaccag ctgagtctcc ttcgacgatg aagagttctg tttcagcagg
    73081 gttattagaa gaacagtctg ctagtttccc tggaaggttg gaaatttcca aaccagattt
    73141 tttacgtgtg acttcacgcg cacgcttggc agccacacga gccttggcag ccaaaattcc
    73201 tttttctacg atacgtttgg caatctgtgg attttccatg aggaaatcgg agaaggcttc
    73261 actgaagagg cgattggtaa tcttgaccac ttcgctattt cccaatttgg tcttggtttg
    73321 tccttcaaac tgtggatttg ggtgtttaac tgagataact gcagctaagc cttcgcgaac
    73381 atcttcccct gttaggttgt cttcattgtc tttcagtaac ttatttttac gagcataatc
    73441 gttgataaca cgtgtcaagg ctgtacggaa accttgttca tgcgttccac cttcatgtgt
    73501 atgaatatta ttggcgaaac tcatgacatt ttcatggtaa cccgttgtat actgcatggc
    73561 tacctcaact gtgatatcat ccatctcacc gtctgtatag attggtgtat caaagattac
    73621 atccttgttc tcgttgatat attcaacgta actagcaatc ccaccttcat aatgataatg
    73681 cttggtttgt tccaaacctt ggcgcttatc tgtaattgaa atttgaagac cgcgatttag
    73741 aaaggccaac tcttgaatcc gtttatttaa tttatcaaaa tcaaagattg ttgtttcagt
    73801 gaagattttt gggtccggtg tgaagtgaac agttgttcct gttttatccg tatctccaac
    73861 tatttcaagt tctgcgacaa catgaccacg acggtattct tggtaatgaa tcttaccatt
    73921 tttgtgaaca tgaacgtcta attgagtgga aagggcatta acaactgacg accccacccc
    73981 gtgaagacca cctgaaacct tgtatccacc accaccgaac tttcctccag cgtgaaggac
    74041 tgtaaagacg gtctcaacag caggacggcc tgttttttcc tgaatatcga ctgggatacc
    74101 acgcccatca tccacaacag taatcgaatc atctggctca ataaaaactt gaatatggct
    74161 ggcaaatcct gccaaggcct cgtcaattga gttatcaaca atttcccaga ctagatggtg
    74221 aagaccttct tttgaggttg atccaatgta catccctgga cgcatacgaa cagcctctaa
    74281 gccctctaaa acttgaattt gactggcatc ataatcctgt gcctgcagat ttttgatttc
    74341 ttctgtcatc ttattccttt ttcttatatg tctaatactt gtcttaaatt cacgatactg
    74401 gtaaacaagt gggtatcaag tcctgcagct tgacctgctt cgatatcaat cggccgatca
    74461 ccaatgacaa gaccagagct aatctgatac ttttctctta aataaagcat ggattcggga
    74521 tttggctttc tcttaaagcc tgagctagaa gtcaccactt ctgtaaaata agctgctata
    74581 gagggttttt ctaaaatttc caaaacctga tcgtttcgat gagagaccaa aaaatgacgg
    74641 ccaccttgat ttgaaatgtc ttccaatagg tcagaaactc cttcaaataa aatcgggtgt
    74701 tcaagctctc tggcttcatt ttccttgtac ttttctaaaa aattctctaa attgggagcg
    74761 aatgtctcaa tcgcaaaagg agtagaaacc tttaaagctt gatagacact gtcatggtct
    74821 tgtgtgatac catacagtgc caatgtttca acaaatgcag ctgttgaagt ttcataatta
    74881 tccagtaaag ttccacctaa atcccagatg taatcgtgat atttcatacc cttcattata
    74941 gcattttttt atgaaaaaag cgatgatttc cctgagtttt ccacataaaa aacgagagaa
    75001 taactcccgt tttactgatt tttaccaaag acatctcgat agagcattcc tgttcgtaaa
    75061 ctctctgcgt cccctcctag ttgctccacc aactcgtagg caaaggcaag ggctgttgaa
    75121 ggaccccgac tggttgtcaa ctgaccatct accactactg tttccttgac gtagtgacca
    75181 tcaaggattt gctcttgaac gccgtcataa caagtgtatc gcttattttt caatatctct
    75241 gcttgattga gggcaattgg tgccgcacaa atggctgcta gtttcttccc ttcttgctcg
    75301 aagctttgca attcttgaat caaggtctga ttatcacgta aatgtgcaga accaggcata
    75361 cctccaggaa gaacaatcat atcatagtct gataaatttc catcaaagac atgatctgct
    75421 cttacttgga ttgcatgcga acccgttact tgctcttcaa aaccaaccat atcacatgtg
    75481 atattggctc gacgcaagac atctacaact gtcaaggctt caatttcttc aaagccctga
    75541 gctaacataa ctgctacttt taccatgatt ttctccttat ttaatttgtt ttaatacaac
    75601 ctttttccgt ttgaatggga cttttccgct cttttcttca gctagattag tctggtaact
    75661 catcgataaa agcaaaccaa caccaatcag attactgata atagctgatc ccccttgcga
    75721 aatgaaaggc aagggaatcc ccgtcaaagg aagtagtcca gtcacagcac cgatattctc
    75781 aaagatgtgg aagagcaaca tcataatcaa acctgtggaa atataagtgt agaactggtt
    75841 atttgattta agagtaatct tcaacatacg gtaaatcaac atgagataga gggcaataac
    75901 caggacagag ccaataaagc caaaatcttc tgcaataacc gtaaaaatca tatctgactc
    75961 tcgaactggg ataagcagat tcgaagcatt aaatccctga ccaaataagc caccactccc
    76021 aatggcaatc tgcccttgag cctgctggta agtcgttgtt tgggcaaact caaagggatt
    76081 gagccaagcc aaaatccgat tgatttggta ggtcggcatt ccaatctggt gaagaaaagc
    76141 tcgtccgtcc ttgctaataa agatagctaa gaaaccagca actcctgtta cagcagtcac
    76201 aaatactggg ataataattt tccaagaaac ccctgataat aaaacgattc ctgagaaaat
    76261 ggctacaaaa accaaagccg tccccaagtc actttgaagt gctaaaagaa ctaggactgg
    76321 aatggtaaag agaatcatcc agaaaattaa caaaaagtcc agcggaaccg tgcgtctcca
    76381 ttccttatgt ttctttgtaa attggacaat gacacgagcc aacatgagga tataggatat
    76441 cttcataaat tctgacggtt gaaatagggt aattccattt attgataccc agtttttggc
    76501 acccgttgat gcaactaagc ttggattata aaatacaatc ggcaagatca taagtcccaa
    76561 gcctaaaata tatagaaagg gggtcacctt ccaaagaaat tctgtattaa agagcatgac
    76621 cacaaaacca atcacaagcc ccaaggcaat ccaggcgacc tgctgcccta aaatgggcag
    76681 aatattattg gggtaatcat gactaacggc tatatagata gccaccacac cgatgaccag
    76741 tagaaaaaat actggcaaga gcaaactgta atcgactctt gagtcgagag aacgtttcat
    76801 atatactaac cttatacttt catacaatac tatttatcaa agttcattaa aaaatctatc
    76861 aatagcctcg tcaacttcgg atcgagagat ggttttaaca gtcgcttctt ctgctagaga
    76921 tgctactatt tgtttgccgt atcgttttcc gacgattctc ctatccaaaa taagagttaa
    76981 ggaacgttgg tattcacgtc tcatacttct tcccaaagcc tgttttaaac gaataatggc
    77041 cattggcaat tgataatcat aaaaggcatt tttcccttct tgattcagtt cttgattaat
    77101 ctttttcgtc aagggttctt gaggattttg gaaaggaagc ctcggtacaa cttgaatcac
    77161 aaaaggatgg cttgaaaaat caactccctc ccagaaactt gctgcaccaa gcaagatttg
    77221 ttgttcacct ttttcaaagc gtttctttag ctgatgaaca tccccatttt tatactgggc
    77281 caagtggcta actgtaagta aatccgatac tgctagaagc atgtctttag cggtaaagag
    77341 aaccaaaatc ggttgctgga aagcttgaat ttccactagt aaagcagcta cctctctggc
    77401 atagacttct aaggaggttt ctgttaccag agggaaatct ttgaccatga ccacttcttg
    77461 ttcctgtttt ccccgagatt caatcttgac aaatttagct tcaggatagc ctaaaaggtc
    77521 tgccaaagaa accctctgac taatctcaag agtagccgat actcccagga cttggcaact
    77581 ctcaggaagt aaagaggaca gaagagtacg gcctgatttt gtagaagaaa tctgaatttt
    77641 cttttgactc gtttcagtta cttcaagcca gtaatcacct tcagctgtaa aatagcgaac
    77701 cagctcatca aagccttcta cttctaattc tgaaaaatac tgatggagat tatccagaga
    77761 atctaagata tttttcctag atttgccaga ctgaaattgt tctatcaagt agagacactc
    77821 aaagcgaata ctttctagta tccgttgttg aaccctgttt tcttctccta ctaaagcctt
    77881 atcaattaaa tcgataatag attgtatatc gtaggtctct tgaagcagat tttctagagc
    77941 taacaaaatc ttttggactt catcaataat cagtaaacgg tcactgacaa attcaggatt
    78001 atcttcaagt ctggtcacga gataggcatg attagtcact aaaagcttgc aagtctctgc
    78061 cctttcttga ctacgtttcc aaaaatcttc cgtcacaaat aagctatggg atgataaatt
    78121 cccatcatga cgaaggtctg ctagaaaatg ttggtaacgg tagagttgcc cgatttcatc
    78181 caaatctcct gtctctgtct cagtaagcca gaccaagact tgcattttaa agcgtctaaa
    78241 taagcgattt tcatcatttt cctgcaagga atgataaaag gcatccaact tcagataatt
    78301 ttgtggtccc tttaagctat gaatatctgt atggaacact tccttgagac gtttaccttc
    78361 ttcttccatg atttgatttt gaagaatctt tgtcggaaca ctaagaacaa tttgtcgctc
    78421 tttggattga gataaagcgg gtaagagata gccataggtt ttcccaatcc ctgtcggcgc
    78481 ttgaatcaga gagacaggtt catctttcaa tagcaagcca acctctttag caaaactttc
    78541 ttgttcctcc ctcacttcaa ggttcaacag agaaatattt ttagaaaagt cttgagatag
    78601 ttttcgtagc tccagagaag ctgccgtttt cttaaaatac agaccttgaa cttggaccaa
    78661 gtctggagaa ctcaggatag attggttgcg ataagtttcc tcaataacca ggtaggactc
    78721 atataggaga gcgtcagcca tttccagcaa gcgttccaag agacctttag gaagctgggt
    78781 catcttttcc cgtaaaaaaa gaagtaattc tgctgtagct tgggcatctg aaagggctgt
    78841 gtgtgcgtgt ttaagaggaa ttcctaattc tcgacacaaa atcggcaagc tatatttttc
    78901 cagttcaggg aaaaagacct gggccaattc gaccgtatca acacgagggt ttcttagctc
    78961 atagccttca aaaaataaat tttccgccaa gagattagca tcaaactgaa cattatgggc
    79021 tacaaaaatc ccatcctcca ccaagtcaaa gatttttctg gcaacttgcg aaaaatcagg
    79081 tgcttgcgcc agacgttggt ctgtcaatcc tgtcagttct ttgatatgag catccaaggg
    79141 ttcatgtgga ttgacatccg tcgtatagtg atcgacgatt tctccatcct caatcacgac
    79201 aattcccact tggataattt tagccttact acctgtgcta gttgcctcta aatccaccac
    79261 aacatagcga ttaccaatcg ttttcattat aaaaaattat accaaaaaaa gggccatttg
    79321 gcacctgcaa acataggata attttcaaac tcaagaacac tacttttctt agaaatccca
    79381 tcgaatagag cattctagcc tgctgatttt tttaaaatag tgaagaaata cgaaaaattg
    79441 agagaagaaa tgttttcatc ttccttctct caacgaatca tgtattttat ttaaccatgt
    79501 caggatcgta gtcataaaat cctgtatcaa ggaaacggtt tttagggtga agtttacgaa
    79561 cttcttcatc cagcaagaag gcttggtcat ggctaaagtt gccctcttga atcaagctac
    79621 gcgcttggat aaagagtttt gcaatctcaa caaagttctg accaggagtg tagagccctt
    79681 ctagtttcca gcgagtaaag ccatgctcca ccaattctgt taatttgatc atcaaatcaa
    79741 ggtcattgtt ggcaaagata tgggtcccat gattatcttc aaaaatggaa tagtggctct
    79801 ctggatcact tggctcagcc aagaagaggt cacgtttatg cgtcttttca tcatcgatat
    79861 gtgtaaagtt atagtagttt tgcaagagtg gacgtttaga atgatggatg acgctagcac
    79921 cgtaaaccaa aacttcagca ggaatttcca aaatctctgg cattttgaaa agttcagctg
    79981 atggaatttc acgcgccaaa acagcctcag atgcgccagc cttttgtccc cagaagttaa
    80041 tctgacgact gctagttacc atggttgaag catcgtagat ggtcttaaat gaataaccat
    80101 cgcggttaac tacgtaaaag acgcctgcat ccccaatcgt aatatagtct gtcttgattt
    80161 cttccaagaa gtctaagaaa ggcttgatac ggtccatcat atcttggtgc atgagagcat
    80221 tgaccgcaac gagcaattcc ttaccagcat catgaaccaa cttagcgatt tcacgtaatt
    80281 ggtcataact aaaggtcgtt ggcagacgaa ggccaaaatc tttctcaccg acatagatac
    80341 ggtctacgcc agcttcgagt agttgttcaa cttgttcaat actttcagca gttgctgtaa
    80401 tgacaatctt ttccataaga aaaattatac cacatttctc caaaatcatc catgctttga
    80461 aaatgaaaag ggactttatt ctttttgtaa cctttctgta ataattttct gccgaaaaaa
    80521 tgataaaata ggtatgtact gttaaggaga gaatcatgcc cgtaagaaaa ttacaatcct
    80581 atgaggtaga ctatcaagaa gaattaaacc agcagcttcc tcattaccaa gcttatacac
    80641 ctgaagcgca atctgatgcc aatctcaagg aaatcctatt ttttattaat atcgctgttt
    80701 tttgtatctg tattgctatc tttagtttta tctttttagc attaaaatta tcaactgctc
    80761 ttgcctttgc cgcagcaatc ggattcagct tacttgtttt aaaagttcaa cggtctatta
    80821 tcaaacgaaa acgtagaaga taaatccaaa atatcgcccc aattggagcg atatttttat
    80881 tttttctttt tagatggtgt ctgaatggca atcttcactt caaagattgt tcccttgggt
    80941 ttattatctt tgacagtaac agttcctttt agagcatcta caatttgctt ggctagggat
    81001 aatcctaaac caaaaccacc tttttgccgg gttctagcct tgtctactcg ataaaaacgg
    81061 tcaaaaattt tctttttatc ttctgtcgaa ataccgattc cattatcaga aacaagtaaa
    81121 taaagattgc gatcggtcgc cgagataaga aaatcaattt caccatcctc ctcagtatac
    81181 ttgacggcat tatcgaaaag aatggtcatc agttgtttca gaagaagctg atctgtgaca
    81241 attgttcgat ggatacgatt ttcaaaacgg aagacacgat tattttccga agcaatcatc
    81301 tcatagtttg tgaaagttgt attaaaaaag ctagttggaa cttctgcaag ctccggctta
    81361 atcccatcat ctctccgagc taagttcagc aagcttgtcg ttaaaaaacg catatttcgg
    81421 acttcttcca aactcgatgc aatgctttcg ctcacatcca taatggtagc ttctggctta
    81481 cgaaaaaggg tctctaagcg attttgcaaa actgcgagtg gagttcgtaa ctcatgactg
    81541 gcattttcca caaaagactg ttgcttctgc atactctcaa gcaggggcct aacactgacc
    81601 ctagctagat agagactggc aagtaaagac aaaatccaga aactagccat cacgaccaca
    81661 atcaattgct catgcttttg actagcctgc tccaactgac tggtattaat caagacagca
    81721 gcatacttga tattggttga aaccgaacta atattggtct ccatcaaaat cacacgatag
    81781 atttcttcct gcccatagct attaaaaacc tgaatctggt agatatgtcc tagttctttc
    81841 ttttctaact taatcttatc caagcccaaa aatcgatttc cagaaagaag ttgagtaaag
    81901 tctttatcaa agagaatgac ttccgtattg gaactgacat taggttttat ttctacttta
    81961 ctagcgtccg ccctagcatt ttctaaatct ttaatctctt ctgttgccct atttatagcc
    82021 agctgaataa ctgcttgagg attttcactc agtccatgaa gcttatcgtc caccgaagta
    82081 taaagactcg aatgcatgac ttgtaaaata atcagagtca ttgtagaaaa aatcagggtg
    82141 aagacaccga agttgcggat aaaataacta aagtcatccg cataccatgt ttttttaagt
    82201 ttactgaaca tcttttaaaa gatacccaac actacgcaag gtttgcaaat tctctgcaaa
    82261 agtggttccc tttaatttct tacggacttt tgaaacatag acttcgacaa ccgaaatcgt
    82321 tgtatcacta tcaaatcccc atagacggtc aaaaatctgc gtcttaggca aaatcacatt
    82381 ttgattttga aggaaataaa ctagtaaatc gaactctttc cccagcaatt cgacaggagt
    82441 atcttcaact ttaacggtat tggttgataa attaaccacg atattcccat aagtcaaggt
    82501 gttttcatta aacttccctg aacgtttgag aagggcctga attcgcattt taagttcttc
    82561 taggtagaaa ggtttggtca gataatcatc cgctcccagt tcaaatccat gtcccttgtc
    82621 atccaaactt tccttggcag tcataatcag aactggtgtc gtaattccct tttcacgcaa
    82681 ttcttttaag acttggaaac catttttttc tggcaacatc aaatccagca aaatcaagtc
    82741 atagacacca ctctcagctt cgtagagacc ttcttctcca tcaaatacct gcataacatc
    82801 cgcaaaatcg tctaaaaagt caaatactga atttgacaga cctaggtcat cctcaaccaa
    82861 taagattttt atcatgagaa actcctcctt attaaaacta ttataccaaa tttgccttaa
    82921 aaaaaactca actctctgca ttttacatga gatagctgag ttttcttttt attttaggct
    82981 tatttatgca tttccgtatt gaagaacaac tgcttcgact gcagcttttt cacggctaat
    83041 caagtcaaca cgtgctgcaa tttccttgat tcccataccg atgttacggc taagagcaag
    83101 gtcagaaagt tgcggctcaa agaactcctt gtattccgcc aagcgttgct gagtcttaaa
    83161 tacatgagca ggaaggataa caaagctatc aaagctcata tctcctccaa gggctgcctt
    83221 aatccaagcc cagttttcac gcgcccaaga ccaagctgtt ttctgagttg cttgatgagc
    83281 taggaattgg taataccaag cagacaagtc ctgtggtttg accacaaatt tgtccttcca
    83341 agaagtaatc aagttttgga tattatccgc atctgtactg tatgcaagag ctgctgccaa
    83401 ctggcgttta aagacagcat ctgttgcgtg agtataagta tcaagataaa gtgctaacaa
    83461 gtctttagtc tcatgatgtt tcatctcatt aatcagaact tgtgaacgaa tagctgctgg
    83521 gagttctgca agattctcct tgtgtgttgc gaagatttgg ctagcgactt gacgagcttc
    83581 tgcatcattt gagcgaatca tcatcgaaac agccagctga cgaaccaatt catcctcatc
    83641 tgattctccg tctttagctt caaaaccaag acggtcatag ttatgacgag ccaatttagc
    83701 aaccagtcct ttgaaggctg tttcagcatc cgttccttca tcaataaagc gctcaagggc
    83761 tgaaatcact tgagaaacag ctgaaaccac cagataagac tcttccttag caagtttatc
    83821 aagaactgga agcaagtctg cataagaaat gtgccctgcc tcagccaaca aacgacgttc
    83881 ttgaacaatt tgcagtttgc ttgtgttatc aagtgtctct agctcagcaa gaacagcttc
    83941 taacaagtct ccttgatagt cggtaatata gtgggcagta ttttcagtgt tgagacgaag
    84001 agctccttca ttttcagcaa gaagagctgc gtagccaggg atttcgatac tttcagtttc
    84061 gagtgtatca ggcaagcctt tccagttgct attgaggggc accacccaga gacggttctt
    84121 gtcttcgttc tcaccgatga agaattgttt ttgtgaaatc ttcaagacat cattttcaac
    84181 tttgacagta agaactgggt aaccaggctg ttccaaccaa gaatccatga aggctgcgac
    84241 atcacgtcct gacgcttgac caagggcatc ccaaaggtca ctaccaatgg tgttgctgta
    84301 ttggtgtttt tcaaagtagg catgcaaacc tttagcaaaa tcagcatctc ctagccaacg
    84361 gcgaagcatg tgcatgagac ggcttccttt ggcatagacg atagcgccgt caaagagtgt
    84421 attgatttca tctggatgtt taacttcgac gtggacagac tgaacgccat cagtagcgtc
    84481 acgttcaaga gcaagaggta ctccacctgt ttggaaatct tcaaagatat tccagcttgg
    84541 ttcgatggta tccacacaga cgtattccat catattagcg aaactttcat tgagccaaag
    84601 gtcatcccac catttcatag tcacgaggtt cccaaaccat tggtgagcca attcatgggc
    84661 cacaacaagg gcaacttgtt gacggctagc aaatgtagag ttctcatcga caaccaagta
    84721 aacttcacgg taggtcacaa gaccccagtt ttccatagca ccagctgaga agtcaggaag
    84781 ggcgatgtgg agagattgag gaattggata cttaactcca tagtaatctt cgtaaaactc
    84841 gatagagcga acagcgatat ccagtgagaa atcaagattt gaaagtggat gtgctttggt
    84901 tgagtagaca cctaccaggg taccattttt agttttagcg gtcacccctt gcaaatcacc
    84961 agcaacaaag gccaacaagt aagaagacat gcgaggtgtt gtctcaaact tccagatacc
    85021 tgtttcctta cggttttcaa catcgatttc tggcatgttt gacaaggcca attcaccttc
    85081 tgcttggtca aagcgaagag agaggtcaaa agttgctttg gcttcaggct catccacaca
    85141 tgggaaagct tcgcgcgcaa aatggctctc gaactgagta gacaagacct ccttcttgac
    85201 tccatcaact gtataataag aagggtaaat ccctgtcatg ttgtctgtaa ttttaccaga
    85261 aaaggcaaga accaattcaa cttgaccagc ctcagccaat tcgatatgaa gggcttcatt
    85321 gtcatggtca actgtaaatg gacgagcttg acctgcaact tctacagagg tgatttccaa
    85381 gtctttttgg tggagggaga tgcggtcact ctgtgcttga ccagtgatgg tcactttccc
    85441 agaaaaagtc ttggtctcac gactcaaatc taaaaataaa tcataatgtt caggaacaaa
    85501 ttgcttaata aaatgttcaa ctgcttgcat agttttctcc tattctaagt ttaagagctg
    85561 ctgctcttct tcaaacaaac ttattatatc atattttgct tgaaaaaaaa ggattggaca
    85621 gcgatttcca aaactttctt ccttctaata gtctacagtg ggtagacctt gcgaaattct
    85681 tctaaaacaa ccttgctttc agatgtaaaa gtcagcccta cttcacccaa acagtctgtg
    85741 aaaaagtcct catgaacctg gcgccaatag gcaagtgatt tgtctccctc accttcctta
    85801 aaggcatgtt gcgcagaaac ttgattgaag agttcaacag aaacctttgt aatttcgaca
    85861 atgcagacag actgattttg actatctaaa atgatatcga aggtccctac ttggggaagt
    85921 ggttcgtctt ctagtacata gaggtcatag gctgatgctg ttgctgtctt ttctccttta
    85981 aacaccaaat ccgctaaaag atctggttca actccaaaag cccaagcatc gatttcatct
    86041 ccgatcaaag gattgatttg cttgtattta ttccacattt cttgcggtat catgggtact
    86101 cctttgtaat tttttacttt cttcttttat gtgtttaaga tgatctggat ggtcaatctc
    86161 taaatcaaaa atctctggaa tagaactgta gtggataatg cacttgatac ccaactgatt
    86221 cattttttgt atgaaagaag tattcagata gcctgctaca gcaaaatcaa tcttgttctt
    86281 tcttgcttta tcctgcatat ctcttagcat atctaacatt attggacttt ccatatcatg
    86341 ccattgactg tttctcatag tcgcaaaaac aaaggaagtc aaatcattca ttccaactac
    86401 aatctttgaa atgcccgttt ccagtatact agataagtca aaatacgctg acggtaattc
    86461 aatcatcgtt ccgactttcc cagtaaaacc ctgctgacgc aatactgtaa tagcttgttt
    86521 taattggtcg tcatcattga caaaaggaaa gataacagat agattggggt tggtttgata
    86581 aacttctgta acgacatgtg cttcagcctg aaattcatcc aaacacgcca gtaaacgcct
    86641 ggttcctcta tagccaaaca agggatgccc ttcgtcaaaa aactctctag tccccactaa
    86701 acaattggct tctgtattcg ttaattcaga aaaacgatac caaacttctt catctgagta
    86761 cagggagcag atagtctcta gataatcttt tacaaattgc tgacaacttg ctaatatgat
    86821 gttttgatta agctctctca acaaatattc cccacgaatc atgccgacgt ggtgaaatag
    86881 ttgaggataa attttttcaa gaattttttc gccactaagg gcaagttgat ttctcatagc
    86941 cattcacctc gtcttaaaag atacaatatc atatataatt atatcaaaat ttcctctagt
    87001 tcaaaagctt cataaggttc agataactca tatcctaaaa attctgctac ttttttggaa
    87061 gcctcattat gagcatccca aagtggaaac atatctctat ttaaactctc tagaatcatt
    87121 gcagcaccaa gctttttagc aaatccattt ccttgttcgt ttggtctagt tgcaacttcc
    87181 acttcaactg ctttacggta aactaaccct gaggaaatcc cagcaatcag ttcattattt
    87241 ttaagaatca caaagccaaa tccacctttt aaaacaaaat cctgatagga ctcaaaatcc
    87301 ccctgtaaat cctgtgacca ttcttccgta gaaaagcagt tataaatatg attatcaata
    87361 ggcacaatat tgtaaccttc ctctaaatga gtaactagat tatttaaaaa ttcaacttga
    87421 aaatttgcct tatctttaaa agaatagcga gtaaaagaat ttagccccac ttttcgatgc
    87481 agaaaatctt gccaattagt attttctgaa ataataatct tataatctaa accatatttt
    87541 ctaacaaaat cttcccaaaa tctggaatcc aactcccctg ctaggtatag aaaattccca
    87601 acatcataaa agcttgttgt cctatcattg tttcggtaga cagttccaat ttgagattta
    87661 agaccataga gaaccatatt tttcttccat gttttaaata gttccattat ccctctactt
    87721 caccttccaa ttcatgtaag aagtcttgtc cagttctggc aatcctaata attcagactt
    87781 aaccttcaag actaatggcg atgcattttc ttctgtaatc tcttgaatat ccatccaaat
    87841 atatccaagt gaatcattcg caccatcaga cacagcttcc gaaatcgtaa cttgaggtgc
    87901 actctcattc atttcaacat catacaaggc tatgacatgg tgaaccataa aattttttaa
    87961 ctcttccctg acgaaaacat cgtagattcg aggattagag tagcttctaa cagtaaatcc
    88021 cgtctcttcc ataacttctc tagtcagcgt ttccgtcagt ccttcaccaa gttgctgact
    88081 gcctccaggt agatcatacc gatgttgata agggcctctc gttttttcaa tgcaaagtaa
    88141 ctttccattt tcaaagcaaa cacagtagac cccaaagtga tttttgattt ccatccaact
    88201 cctcctactt caaagaccag ccaccatcta ttgtcagaat ttgtccctgc atggcagatg
    88261 cctttccact ggccaaaaag agactgactt ctgccacttc ctctggttca atccagcgct
    88321 tgattggtgt ttcactagcc acccagtcag ctaagccacc tgtctcaaaa tccgcagcgg
    88381 tcatagctgt cttgactgct cctggagcga taccaaagac ctgaatccca gcttcagcat
    88441 agtctagagc caactgcttg gtgaagccag ccaaggcatg cttggatgaa gtataggcgt
    88501 gaccacctcc acctgctagg ctagaagcaa tggaacacat attgatgatg attccctttt
    88561 tattttccag catttgtgtc aaataatacc gagtcaactc tactggaata atgtagttga
    88621 tttcaaaaat ctcttgaatg tcctgcgccg tttgttccaa cagtggtttg taatcatcca
    88681 aaactccggc agtattacac aaaacatcca cctgagggca ccagtcaaaa ataggttcca
    88741 agtccaaggt caaatctctc tgtaaaaagt gaaaatcacc ctctaagagt ggcttttcac
    88801 cttggtcaac tccataaact tgatagccct tctctaaaaa gaggcgagct tgagccaatc
    88861 cgatccctga actcactcct gtaatgagta cacgtttagt catgcacttc tacccaatcc
    88921 gttgccaaaa catcacaaac tgtcgggctc cacatggaaa aaccttctcc ttcgccagaa
    88981 acgttgatta ggaaataagg tgtcatttca agtgcaagcc cattttgctc gatggtatca
    89041 aagagttgga catagttttc cgcacctccc caaccagttc gtacatattt tctcttagcc
    89101 tttaacccag gcaggatctc ttcaaatgtc atgtttttct cctttaattc tacattcttc
    89161 atttaattat agcaaaaaac cactttatac ggctttttga ctgtgagtta ttcaaacctg
    89221 ctactactta cggcaaatta ttccctgcag caagataaat ttcataccat tcttttcttg
    89281 ttaagctaaa gtttgccgct cggctaactt ctctcaagtg cttaggattt gttgtaccta
    89341 cgactgcctg catttttgct ggataacgca atatccaaga aatggcaata gttgaagagg
    89401 ttactccata tttaatagct aaacgatcaa gtacttgatt taaagcttga aatttctcat
    89461 ttccaacaaa gttcccttta aaatacccga attgcaagac agaccatgct tgaatgacca
    89521 catcgtgtaa tttgcaatat tcaaaaatgc tgccatctcg catagctgct tgactatctt
    89581 ccatattaac atgaaaagct gattcaaatc ctggagtaaa agccgcactc aattgtagct
    89641 gattaacagc taacggctgc ttgacatctt ttttaagcaa ctccatcatc ataggatttt
    89701 gattagaaac tccaaaatct cgaactttac cttgtttata aaggagatca aaggcttctg
    89761 ctacttggtc agattccatc aaagcatctg gtcgatgaag gagcaagcta tctagatgat
    89821 caatcttcaa tctttgcaaa ataccgtcta ctgattttat aatatagtcc ttagaaaaat
    89881 caaaataggt aaattcttca atgcgaatgc cacatttgga ctgaatccac atcttttctc
    89941 ttaaatctgg acgatttttt aggacaagac ctaacagttc ttcacaacga ccacgaccat
    90001 aaatatcagc caagtcgaag gcattgattc caacagaaag tgctgtttct acaagctctt
    90061 caacttcttt tacagactta tcttttattc tcatcattcc gagaacaatt tctgataatt
    90121 ctttgtcatc ttgaccaaga gttatgtatc tcatcaaatt tttctccttt aatttctaac
    90181 attcttccct tcattataac aaaaaaccgc tttgcaacgg ctttttgact atacttcact
    90241 ccattttatc ttcttaaacc cacggaacaa gacaaagatt ccaataaaga ggacagctaa
    90301 aggaataact tttgtaagga aaacatttga aattcccatc cactcataat aacggagcag
    90361 agaacccacc acaagatggg caataatcat actgacaaat ggacgaaaga ccgcttcttt
    90421 ccaattccaa ataccgataa ctagcgaaat cgtaaagaca gacaaactat cccagggagc
    90481 cggaatataa aaggctcctt cttgtatgaa gcttgccatt cctacatatc ctaaaacaac
    90541 tagaagaact atagtcccaa caacaatgta agtgccaatt ttcattttag gagaatcttg
    90601 gactaaactt cttcgtaaaa ttgtggccac aagtccaaat ccaatcagaa aaataagaag
    90661 ttgccctaaa aatgtgagca aattgactgt taagagagga cctttagaaa aatcacttag
    90721 tagttgataa taacgtaata ccgccaggac aagaattggc gtcaaaaggg actctttgat
    90781 agaactgcga ggtgctccct tgagaatctc tttcattatt tttttaggat tcttacctag
    90841 ataatcctct gcactcatgc catctcgttc tgcttctgag aaatctagca tcatcaaata
    90901 gatctgctct ctgagatagt cttcatcata gagaaatcca gcaagattaa aactttccca
    90961 caactcctca aaatactttt gattctcctc agaaaactca tgtagcaaag cgcttgtttc
    91021 ttcgtaatac ttcattttct tcatggttta acccccattc ttaatccctt ctactttttg
    91081 actcaaatcg tcccattgtt gccaaaagac tgagacacgc tcttctcctt ctttcattaa
    91141 tgaaaaatac ttccgatctg gaccatctgg cgacgggcgc atgtcgcctc ttatccattg
    91201 atttttttct aacttttgca acaaaggata aatagttcct ggaacgatag tatcaaatcc
    91261 agcctctcgc aaagtctgaa ccaactcata accataccgc tctttttgac caatcatatc
    91321 caagacacaa ccttcaagaa caccttttaa tagctgagtt tctttcatca cttctccctt
    91381 ctaatctatt ttgtaatacc tactagtaac ttcacctata gtatatcact tctacactag
    91441 tttgtaaagc ataatagtta atactcttcg aaaatctctt caaaccacgt cagcgtcgcc
    91501 ctaccgtatg tatggttact gacttcgtca gtttcatcta caacctcaaa acagtgtttt
    91561 gagctgactt cgtcagtttc atctacaacc tcaaaacagt gttttgagct gacttcgtca
    91621 gtttcatcta caacctcaaa acagtgtttt gagctaactt cgtcagtttc atctacaacc
    91681 tcaaagcagt gctttgatca acccgcggct agcttcctag tttgctcttt gattttcatt
    91741 gagtataaat aaaaaaacag aactagcctg aactagtcct gtctactttt acccaatcac
    91801 acttccattt ggtacagctg gatcaactgt gagaagggtt aatttgccat catgttcagc
    91861 tgagagaatc ataccctggc tgacatattt tttcatcatt ttacgtggtt tgaggttagc
    91921 aacgatttga actttcttgc cgaccaattc ttgttcattt ggatagtatt ttgcaattcc
    91981 tgaaagaatc tgacgatctt ctccatcacc agcatccaag cggaattgaa gcaacttatc
    92041 tgaaccttct actttagaca cttctttgac ttctgcgaca cggatttcaa ccttgtcaaa
    92101 gtcttcaaac ttgatttcat ccttgtttag tttgagctca acttcgtccg gattccattc
    92161 tttttcgact gctggtttat tgccttccat ttgttccttg atataggcga tttcttcttc
    92221 catatttaga cgtggaaaga taggtgttcc tttggcaact acagtcacat ctgctgggaa
    92281 gtcagccaaa ctcaagtttt caagactaga aacttcttcc aaaccaagtt gagtcaaaac
    92341 tgcacgacta gtttccatca taaatggttc aatcaagtga gcaactacac gaatgctggc
    92401 tgccaagtgg ctcatgacac ttgccaattg gtcacgaaga gcttcatcct tgtccaagac
    92461 ccatggtgca gtctcatcga tgtatttatt ggtacgagag atcagagtcc agactgcttc
    92521 aagcgcacgt ggatagtcaa ctgcttccat gtgtgtatgg aagtctgcga ttgatttttc
    92581 tgcaacctca gcaagaacat gatcaaattc agtcacacct tctacatagg cagggatttg
    92641 tccatcaaag tacttattaa tcatggaaac cgtacggtta aggaggttcc caaggtcatt
    92701 agccaattca tagttgatac gaccgacata gtcttcagga gtaaaggttc cgtctgaacc
    92761 aactggaagg ttacgcatga ggtagtaacg aagtggatct agtccataac gctctaccaa
    92821 catttcaggg taaacgacat tcccttttga cttagacatt tttccgtctt tcatgacaaa
    92881 ccaaccatgg gcaatcaaac gatcaggtaa tttaacatcc aacatcataa gaaggattgg
    92941 ccagtagata gagtggaagc gaaggatgtc ttttcctacc atatggaaga ctgttccatt
    93001 ccagaacttg tcaaagttac catgttcgtc ttgagcgtag ccaagagctg tcgcatagtt
    93061 aagaagggca tcaatccaaa cgtagacaac gtgttttgga tttgatggga caggcactcc
    93121 ccatgtaaag gttgtacgag ataccgccaa atcttccaaa cctggctcga tgaagttgcg
    93181 tagcatttca ttaagacgac catctggcgt gataaattca ggatgagctt tgaaaaattc
    93241 gaccaaacgg tcttggtatt tgctaaggcg aaggaagtat gattcttcag aaacccattc
    93301 aacctcatga cctgatggag caataccacc agtcacattt ccagcttcat cacggaaaac
    93361 ttctgccagc tggctttctg taaagaattc ttcgtctgat actgaatacc aaccagagta
    93421 ttcacccaag tagatatcat cttgagcaag taagcgttca aagacctgtg cgacaacttt
    93481 ttcatggtag tcatcggttg tacggataaa tttatcgtat gagatatcta gtaattgcca
    93541 gagttcttta actccaaccg ccattccatc aacataggct tgaggtgtaa taccagcttc
    93601 ttccgctttc tgctggattt tctgaccatg ttcatcaaga cctgtcagat aaaatacatc
    93661 gtagcccatc aggcgtttgt aacgtgctag gacatcacat gcgatagttg tgtaggcaga
    93721 accgatatga agtttcccag atggatagta aatcggcgtt gtaatataaa aatttttttc
    93781 agacataatt tttcctttcc aggcaaatga aacctgtttt tctaacactt cattatatca
    93841 catttttaat gaatttcgat agggaaatcc atacaaaaac aagatagacg agtgtccatc
    93901 ttgttgatct cattcataac gaagggcttc aattggatca agtttcgatg ccttgttggc
    93961 tggcaagact ccaaaaatca taccaacact agccgaaact gcaagactaa atagggcaac
    94021 tgggattgat actccaactt ctataccttc tattaaacct tgcagtaaca aacctgctaa
    94081 ggcagttaaa ccacttgcaa ttgtcaagcc aattaagcca cctaacaagg tcaaaatcat
    94141 ggattcaatc aaaaactgaa ttaaaatatt ggcacgtgtt gcacccaaag ccttacgaag
    94201 accaatctca cgagtgcgct ctgtcaccga aaccagcatg atgttcatga caccagttcc
    94261 tccaacaaag agagaaatcc ctgcgatgga actaataatc gtcgtcataa aactaaacga
    94321 ttgttgaatt tctgcaaata caacggactc atctgccacc tggtattctc cctgttgtaa
    94381 gcctgcaagc tctgtcattt ttcgtgccag ttctggaccc agagttgggg ttaaactggt
    94441 atcattcact cgaaagacaa tactagctat ttcatctata ttaaaattcg cagcaaggga
    94501 gatattggta gtaataggca agccaccaaa cccatatatt tttgaccttt tagcctccgg
    94561 actagtataa accccaatga cccggtaact aaatccattg acttctacaa ccttgttaat
    94621 agcctcttga ggagattcaa ataaactaat ggacaattcc tcatctagca aaataacact
    94681 tgcaaactct ttgaaatctt gctctctcag actacgacct gcaataattt cattcttaac
    94741 agcgtccatg taagttctgt ttccacctgt caaattagta ttctcaacct ttttatcttg
    94801 ataggtcaag atggcattcg ttgaattggt tacatagtaa ctatccactc ccttcagttt
    94861 agctgcctct tgaacccagg attcttgcgg ttttggcggt tcaacaggaa cttcctcttc
    94921 ctttccagaa accgtaaaag ctgattgttt ctgagtaaaa gacccatctt tacttttttt
    94981 aggagagaaa aagacgctaa tatttttctg agatttagtc atatctttat tgacttgacg
    95041 agatagggaa tcacccaaag ccataatcac aacaactgat gaaacaccga taataatccc
    95101 aatcatagta agcaaagaac gcatcttgtg agccatgata gatgaaaagg caaatttcag
    95161 attctgcatc ttagttttcc tcctttccta actgagcact gtcagacgaa atgaccccat
    95221 cccgaatgac aatctgacgt ttggcatagg cagcaatctc aggctcatgc gttaccatga
    95281 taatggtttt tccttcttta ttcaaatcaa ccaataattg cataatttgg ttacctgttt
    95341 tggtatccaa ggctcctgtc ggttcatccg ctaggataat agaaggattg tttaccaagg
    95401 cacgcgcaat ggctacacgt tgcttttgac caccagataa ttctgaaggt aaatggtgac
    95461 tacgttctat caattcaacc ttgtctaaat attcctcagc caacttgcga cgttttgaag
    95521 acgaaactcc tgcgtaaatc aagggcaatt ctacattttg cagagcattg agcttcgata
    95581 gaagaaagaa ctgctgaaag acaaaaccga tttgttggtt acggacctta gctagttgtt
    95641 tttcaccaag cccagccact tcttgacctt caagataata ttctccactg gttggtgtat
    95701 ccaacatgcc aatcgtattc atcagagtgg acttaccaga cccagatggt cccatgatgg
    95761 ctacaaattc accctcattc acttctagat tgatattttt gagaacctgc agttcttggt
    95821 caccattacg gtaacttctg aagatatttt ttagactaat tagttgcttc atcagccttc
    95881 acctcttttc cttcttccaa ggaagatgtt ggattactga tgaccttagc accgttcgtt
    95941 aaaccagaag tgatttcttg attttctgcg tcagcatttc ccaatgaaac ctcaactttt
    96001 ttagcctttt gttgttcatc cacaatccag acataatttt tactatcatc cattactaga
    96061 ctgctaacag gaacaagaat agccttagtt ttgcttttaa cctcaatgtt gacagaaaaa
    96121 ccttgtttca aatcaccaac ctcgcctgtc acatcaatag tataagggta tttagaacct
    96181 gtattattcc cggctgctgg actagctgct tcaccattgt ttttaggata gtcagaaata
    96241 tagcttaatt tcccagtcca ttttttatca ggatacactt tagaagtaaa gcttacttct
    96301 tgacctacag aaaggttggc tagattgtac tcagacaatt ctcccttgac ttgtaaattt
    96361 tcattgctga caatatgaac cataacttga ctcgcccctg ttggagattt agaaacattg
    96421 ctattgactt cgactacagt tccctctagg gtactgagaa cagttgttgc atccaattga
    96481 ctttgagcct tgcttaattg cgctgcagca tctgcacgcg catcacgggc atcacccaat
    96541 tgagcatcaa tagaagcaac agaatttcca gccactggag ttgggctttg caccgttgca
    96601 tcttctcctc ctactggcgc tggtaactgt ggagcctgag ctgaagcggc ttcatttcgt
    96661 gcttgattga gttcattgat atgacgatct gccttagcta ctgctcgact agctgaatca
    96721 taggccgcct gcgcttctga actactgtac ttgactaaag cctgcccttc gctgacctta
    96781 tcgcccacag aaacaaggat ttcatctaaa tcacccttac tagcatcaaa ataaacatat
    96841 tgttcatttt ttgctgttac tgtccctgac aataaaacag aggatgccac gcttccttcc
    96901 ttggcaacaa caagatgagt aggctcatct tttacagcag tctgagaagg ttgtctaaaa
    96961 agtaaaatcc ccccggcacc caatacaact acactcgcag caccgattgc tgcatacagt
    97021 tgccactttt tagctttacc attctttttc ttcataatga aactcctttt cttttttaca
    97081 atactttgct attataccaa atttccctcc agcaaacaat gcagttcaga tggaaataat
    97141 ggcagttcag gattaaacaa tcgttcggaa ttttactttt ctattgtact agatatataa
    97201 tacactatct tgacttattt ggcaagcttt tttgcaattt tttgtgcgta gcagattttt
    97261 gcaatcaaat caaaaaaaga ataaaatata actatcaaaa aagacactct actatttaaa
    97321 agattacaaa ggagttttca atgagagaat atgatatcat tgctatcggt ggaggtagcg
    97381 gaggaatcgc taccatgaac cgtgctggtg aacatggagc caaagcagcc gttattgagg
    97441 aaaagaaatt aggtggaacc tgtgtcaacg tcggttgtgt tcctaaaaaa atcatgtggt
    97501 acggggcgca aatcgctgag actttccatc aatttggaga agactacggc tttaagacta
    97561 ctgatcttaa ctttaacttt gcaaccctac gtcgcaatcg tgaagcctac attgatcgcg
    97621 ctcgttcttc ttatgatggt agttttaaac gcaacggtgt agacttgatt gaaggtcatg
    97681 ctgaatttgt agattctcat actgtaagcg taaatggtga actgattcgt gctaaacata
    97741 tcgtgattgc tacaggtgcc catccaagta ttcctaatat tcctggtgct gagctaggtg
    97801 gctcttctga tgatgtattt gcctgggaag aacttccaga gtcaattgcc attctaggcg
    97861 ctggttatat cgccgttgaa ttagctggcg tactccacac ttttggtgtc aagacagatc
    97921 tctttgttcg ccgcgatcgt cctttacgtg gttttgattc ctacatcgtt gaaggtttgg
    97981 tcaaggaaat ggaaagaaca aacttaccac ttcacactca caaagtccct gtcaagttag
    98041 aaaaaactac tgacggcatt accattcatt tcgaagatgg tactagtcac acagctagcc
    98101 aagttatctg ggctacaggt cgccgtccaa acgttaaggg attgcaactt gaaaaagctg
    98161 gagtgactct gaacgaacgt ggctttatcc aagtggatga ataccaaaat actgttgttg
    98221 agggaatcta tgctctaggt gatgtaacgg gcgagaaaga actgactcca gttgcaatca
    98281 aggccggacg taccctatct gaacgtctct ttaacggaaa aactactgca aaaatggatt
    98341 actcaactat tccaactgtt gtcttttcac accctgctat cggaactgtt ggtttgacag
    98401 aagagcaagc tattaaagaa tacggtcaag accaaatcaa ggtttataaa tcaagctttg
    98461 catctatgta ctctgcttgc actcgcaacc gtcaagaatc ccgtttcaaa ctcataacag
    98521 ctggttcaga agaaaaagtt gtcggacttc atggaattgg ctacggcgtt gatgaaatga
    98581 ttcagggatt tgccgttgct atcaaaatgg gagcaaccaa ggctgacttt gatgcaactg
    98641 tggcaattca cccaactgca tctgaagaat ttgtaaccat gcgttaatcg aaacaaaaga
    98701 agctgatata aatatgtctg cttctttttt aatgattttc gaatcaacaa aaaaattatc
    98761 caacttgact agtcacgaaa atcggctgtt acagtttttg ttaccttgtt tttaaaaaat
    98821 ggttgacatc gactcctata tgagtataat agttactata cattagaaaa gaggttaact
    98881 attttgaaaa aagctcacgt ttatgctatc cctgctattg gggctgctct cattgctgct
    98941 ttggcacaaa tcagtcttcc aattggacct gttcccttca ctctgcaaaa ctttgcaatt
    99001 ggcttgattg ctactgtctt tagaccgaga gaggctatac tttctgctgg actctatctt
    99061 cttctaggtg ctatcggtct tcctgtcttt gcaggaggtg gagctggttt tcaggcttta
    99121 gttggcccta ctgcaggcta tctttggttt tatctcgttt actctggact tacttcctct
    99181 ctaaccaaca gcaagagtgg tgttgttaag atttttcttg caaacctctt gggtgatgcc
    99241 cttgtctttg tcggcgggat tctcagcttg catttcctag ctggaatagc atttgaaaaa
    99301 gctcttgctg tgggggttct tccttttatc attccagacc ttggcaaact tctggctatt
    99361 agttttatta gccgtcccct acttcaacgc cttaaaaatc aggcttactt tactaactaa
    99421 aaaaggatat cgagttatca tgactcaata tccttttctt ttattttgaa aacttatact
    99481 caatgaaaat caaagagcaa actaggaagc tagccgcagg ctgctcaaaa cactgttttg
    99541 aggttgtgga tgaaactgac gaagtcagta accatacata cggcaaggca aagctgacgc
    99601 ggtttgaaga gattttcgaa gagtattagt tgcctttaaa ggcatccacc atcgtttgaa
    99661 attcttcatt tgagagagta atccctttgc ccattttagt atggtctgga ctccaagcac
    99721 gaatatcaaa ctttgcaggg gcaccattaa agctcacacg gttaatttcc ttggtccaac
    99781 ctttttcgtt ttcagaaaga gtcaacaagt gctcttcgat ttcaaatgta aattctgcca
    99841 ttttcttctc cttttttagt ttcattagtt tattcgtaaa atcttgtaga ttttaggaaa
    99901 attttatata atattgatat aaaagaaggg aggccaatat gagacataaa ttccagcaag
    99961 ttctaaataa aatacatgat tttttaaatg gatatgacca acctgaccag actgaaacca
   100021 actcccttac agccactatt gaagaggcta tccagaaaca aaccgctgtt caccttatct
   100081 tgtctgagac aagctttaca ggtgacatca tcaaatatga tcagcaaggc cagcaaatta
   100141 tcgtgaaaaa tttttccaaa aatgtgagcc ggattatccg tataagcgat attcaacgcc
   100201 tgcgatttgt cccctcaact gtccaaacag cccaaaaaaa tagatttaag aaagagtgag
   100261 atgtagttgc ttcatcccac tctttttctt agcgaatttg ttcaaaatgt aaatgaactg
   100321 caatatgatc tccataacca cttctttcca agtcacgttg taaacgatag gaaatgtagt
   100381 gttctgcaat ggtaatgtaa cctgcgccca ataaacgatg ttcaaccata gattgaatca
   100441 tactgatagt cgcacgttcc accttggctt cttgtaaatc caaaactacc ttcttagtga
   100501 cttgagcaag attttgacgc aaatcatctg tcaaaacata aacagtttgg gctgccttca
   100561 agatggcttg gtaaatctta tctggattaa attcagcaat ttcgccatta cgtttgatta
   100621 cttgcatagg tttctccttt attctttgtt ttctttgatt tctgccagca ttttttcttc
   100681 ttctactgtc agttgataat gttcaagtaa atctggtctg cgctcgtagg ttttctttaa
   100741 actctcgtac aatcgccact gacgaatctt ttcatggtgg ccactcatca atacatctgg
   100801 cacgaccatg cctcgataat catagggacg tgtgtactga ggatattcta aaagacctga
   100861 agaaaaacta tcatcttggt ggctagactc cttgccaatc acttctggaa tcaggcgaac
   100921 tgtagcatca atcatggtca tagctgccaa ttctccacca gtgaggacat agtcgcctag
   100981 ggaaatctca tctgttacca aggtcttaat gcgctcatca taaccctcat agtgcccaca
   101041 gataaagatt agctcttcct cttgagccaa atcttcagca taagcctgat caaactgctt
   101101 tccagcagga tcgaggagaa taacgcgcgg atttttcttt tcaatagcat caaaggaatt
   101161 gaaaataggt tgtgctctga gcaacatgcc ctgaccgcct ccgtagggct catcatctac
   101221 atgacgggcc ttttcagcat tttctcgaaa attatgatac tggatatcca agagcccttt
   101281 ttctcgagcc tttccaacga ttgagtgctc cagtggagaa aacatctctg gaaagagggt
   101341 taaaatatca atcttcatcg tctaaccctt ctaagatttc cacatcgacc cgtttatttg
   101401 gaatatcaac attgagaacc actggtggga tataaggtaa aagcaaatca cgtttgcctt
   101461 ttcgtttgac cacccagaca tcattagcac ctggttgcag gatttccttg atggttccaa
   101521 ccaagctatc accctcatag acttccaaac cgataatctc gtgatagtaa aattcaccat
   101581 cgtctaggtc attcaaatct tcctcagcga ccttgagact gtatcccttg tacttttcga
   101641 tagtattgat atggtacata tctttgaatt taataatgtc aaagttcttc tgtttacggt
   101701 ggctagcgat ggtcactgtt tggacaaact gatctttttc atcaaacaaa gccagctcag
   101761 ctcctttttt aaaccgttct tctgcaaaat ccgtcacaga caagactcgc atctcaccct
   101821 gtaatccctg cgtattaacg attttcccaa cattaaagta gttcatcttg tctcctgtaa
   101881 tctccttttt tccatcttat tctgacaatt ctcgaataat agccgcaatt ttttccgatt
   101941 ctgaccattg taaataatgg tgattccttc ctaaaatgag tttagtattg gaagtccaat
   102001 attctgattc tctgtactct ttttctctat aagtctgaca aaaaataaat acagggacat
   102061 gagattctat cgacaaattc tcaaaatctt cctcagtaat ctctccagat atctgaaatt
   102121 ctggatcttg attttccaac tctaagcctt tttcttgcat taattcccag atttttttat
   102181 tcgtttcagg actaaatgtt gcttgagtta agttcttaaa ataaagttca ggaccacact
   102241 cgtcaatcag cctcatctgc tcttccattt ctggataagg attttctgaa aaatcagcaa
   102301 acatgacttt tttagttgtc ggttcaattg ctactaaagt ctgacgctta attggtttct
   102361 cgagtaattt gcaagctaaa attccactcc aactatgtgc acaaagtata tattcagaaa
   102421 ttcctaattc ttcaagtact tcataaaccg catctgcaag attatctaga ttttttccag
   102481 cttggtcatg aatcggactc ctacctgtgt tcggaaaatc aattgtcaaa taaccaattg
   102541 taggaggagg tttttcaagt ataagtgaaa aattttcata acttggtagc aaacctgctc
   102601 cgtttagaca aactagcact ttcttttgct tttgataagt aacagagagg ctaccaattt
   102661 ctgtagatac ttcaaacctc ttcataaaga aatccactca ttctatataa tgaattatta
   102721 aaaatcctta tcctttattt tatcacgttc caaagatttt ctcaagttgg aggaagggga
   102781 caacatctct actttccctt caagaatcct tccaaatcat gtttatgttg gtaattaacg
   102841 gctgcggttt tgtctttctc aaagatggtt ctagttaggt caatatgctt gatagcagca
   102901 atagcgacgg tgtagtgaat gatatcagcc agttctatgg caggttcctc gttcgaatcc
   102961 tatcccttct tttcgaccag agcgcctatt caaaacctcg gctacttctc cgacttcctc
   103021 cactaacttc ataaagagac cttcatcagt ccgagactgc tgttaatgtt cgagtaagta
   103081 gtcttggaat tgcctaaacg ttcaatcttt tatagtatat tgaaactaga atagtacacc
   103141 tttacttcta aaacattgtt agaaatcgat ttgactgtcc tgatcgattt gtcctgttat
   103201 tatttcattt tactatatct tctattccac acaaaaaagc gagacatccg tcccgccctt
   103261 cttatttttc gtcaataacg attcttactt ttttgtattc agttgggaca gagtagacaa
   103321 tcgttcttat cgcagaaata gtgcgaccct tacgaccgat tacacgaccc acatcgcttt
   103381 gatcaagatt caaatgatat tccaaaaatt ctggtgtatc ttcaatcttg atagttaagg
   103441 catctggttg tgaaattaag ggtttcacaa tcgcaataat gagattttca atcgtatcca
   103501 tctgtcaacc tactttaaac ttattttgag aatttagaat cgtggaattt tttcaatacg
   103561 ccttcttttg aaaggatgtt acgtactgtg tctgaaggtt gagctccatt agccaaccat
   103621 gcaagaacgc ggtcttcttt caaagttact tggttttcag caacaagtgg gttgtaagtt
   103681 ccaactgttt cgatgaaacg tccgtcacgt ggtgaacgtg aatctgctac gttgatacgg
   103741 tagaaaggtt ttttcttaga acccatacga gtcaaacgga ttttaactgc catttttaaa
   103801 gtctcatttc tttaattttt tatttcggtg aaatagctga gctatttagc acatgttcta
   103861 ttatagcaga tttttggcat gtgtcaagaa aaaaacttga cagactataa atttcttaaa
   103921 gtatttagaa atttgttaga ataggaaata aatgtttgaa agatactatc cgtgaatact
   103981 attttagaaa aattttataa agaacaccaa gtcaaaccct tcatatcgcc tgaacgagat
   104041 ttggatactt ggctcctaag tcccaagccc gttcccaagc gaaatatgaa cttattagca
   104101 gatgattcac tagcaggaga tatcatttta ctatggagaa tccagtttgg tacttttacc
   104161 actgaaacat gattttaaaa actcccattc gaatatgatt caaaattcgc ttagaatcaa
   104221 tgttttcccg ctttttcaaa aaataaattt tcatctaatt taaataactt tcaattaagt
   104281 gtgaattttg cttaaaatca ttaaaaagca ccccatggtg tgaaccatga agtgttgtaa
   104341 atgctgtgtt gtagctagtt cttagcgttt agagaactgg ctagctttac gagctttctt
   104401 aagatctggt ttccaaaata ctttgagtac acttatggta ttgatgcccc taaacatcta
   104461 aaaactctgg tagaaaaagg gtatgctctt gtcgaaactt cttttgactc acttgaccat
   104521 ctaaatacta ccatgaaaaa gaatatcctg aagaagaagg gagttactgg actttctaaa
   104581 atgaaatctt gcgacctgga tcaagccctt catgagcatt tttcagaaga agaattagct
   104641 ggtcactttc atgtccttct atggactttt ttacaatggc attgctatca cacccaatac
   104701 ctatctaagc gcctggttcg taaactttat tgcagctctt cctctaaatt tcctaattgt
   104761 tgaaccaatt gcccgtttta tactaagttc ttttcagaaa ccatttactg gggaagaagt
   104821 tgaagaagtt gaagattttc aagatgatga tgaaatccca actattatct aagccagttc
   104881 tgtaaactac taatatttga aatccacttc cttttagggt acaatggtat aaatgaattt
   104941 ttgagaggat cagaatgaaa aaactagcaa cccttctttt actgtctact gtagccctag
   105001 ctgggtgtag caacgtccaa cgcagtctgc gtggtgatga ttatgttgat tccagtcttg
   105061 ctgctgaaga aagttccaaa gtagctgccc aatctgccaa ggagttaaac gatgctttaa
   105121 caaacgaaaa cgccaatttc ccacaactat ctaaggaagt tgctgaagat gaagccgaag
   105181 tgattctcaa cacaagccaa ggtgatattc gcattaaact cttccctaaa ctcgctcctc
   105241 tagcggttga aaatttcctc actcatgcca aagaaggcta ctataacggt attaccttcc
   105301 accgtgtcat cgatggcttt atggtccaaa ctggagatcc aaaaggggac ggtacaggtg
   105361 gtcagtccat ctggcatgac aaggataaga ctaaagacaa aggaactggt ttcaagaacg
   105421 agattactcc ttatttgtat aacatccgcg gtgctcttgc tatggctaat actggtcaac
   105481 caaacaccaa tggcagccag ttcttcatca accaaaactc tacagatacc tcttctaaac
   105541 tccctacaag caagtatcca cagaaaatta tcgaagccta caaagaaggt ggaaacccta
   105601 gtctagatgg caaacaccca gtctttggtc aagtgattgg cggtatggat gttgtggata
   105661 agattgctaa ggccgaaaaa gatgaaaaag acaagccaac tactgctatc acaatcgaca
   105721 gcatcgaagt ggtgaaagac tacgatttta aatcttaaaa acaaaaaaaa tacagtatcc
   105781 acattcggta ctgtatttct tttactctca ttcttaagtt aaattattaa aatcccatat
   105841 ttggtctatc caaccttcat aaaagtctgg atcgtggcag accataagga tagatcccct
   105901 gtattctttg agagcgcgtt tgagctcatc ctttgcatcc acatccaaat ggttggtcgg
   105961 ctcgtccagc actaaaacgt tgttttcacg attcatcaag agacagaaac gaaccttggc
   106021 ttgctctccc cctgataata cttgaatctg gctttcaata tgtttggttg tcaaaccaca
   106081 acgggcaagg gctgcacgga cttctgcttg attaagggca ggaaaggcat tccagacagc
   106141 ttcaagagga gtttggcgat taccgccttc tacttcctgc tcaaaataac caagttctaa
   106201 ataatctcca cgctccactt ccccagcgat tggcgagata atgcccaaga gactcttcaa
   106261 gagagttgtt tttccaatac cattagcacc aataatcgca accttttgat tgcgttcgaa
   106321 ggtaagattt aaaggcttag taagaggacg gtcgtaacca atttgcaagt tcttggcttg
   106381 gaagataaag cgccctggtg tacgagctgg tttgaaatca aaggatggtt ttggtttctc
   106441 actttggagt tcgataatat ccatcttatc caatttcttt tgacgagaca tagccatatt
   106501 acgagttgca acacgggctt tattacgagc cacaaagtcc ttgaggtctg caatctcttt
   106561 ctgctggcgt tcgtaggctg cctctagctg agatttcttc atagcataaa cttcttggaa
   106621 ctggtagtag tcaccagagt aacgcgtcag ctgttgattt tccacatgat agacaatatt
   106681 gataacgtca ttgaggaatg gaatatcgtg cgaaatgaga acaaaggcat tctcatagtt
   106741 ttggagatag cgcttgagcc aatcaatatg ctcagcatcc aagtagttgg tcggctcgtc
   106801 caacagcaaa atatcaggct tttcaaggag aagttttgcc aaaagcacct tggttctttg
   106861 cccacctgac aaagaagtta catccgtatc catgccaaag tccataatac caagagcacg
   106921 cgctacttcg tcaatcttag catccaaggt atagaaatca cgactctcca gacggtcttg
   106981 aagttctccc acttcttcca tgagagcatc aacatccgca ccgtcttcag ccatttccat
   107041 atagaggtca ttgatacgag cttcagcttt gaaaagctca tcaaaagccg tacggagaac
   107101 atcacgcacc gactgtcttt cagcaaggac agagtgctga tccaagtaac cagccgtcac
   107161 atatttggac cactcaacct ttccttcatc tggcagcatt ttaccagtca cgatactcat
   107221 aaaggttgat tttccttcac cattggcacc gaccaggccg atatgttctc ccttgaggag
   107281 acggaaggac acatcttcaa aaattgcacg gtcaccaaaa ccgtgactca gatttttaac
   107341 ttctaaaata ctcattttaa ttccttatct tgtttttatg taatcgttta taaaggagcc
   107401 aagacagata gccacccaaa gtgttggtcc acaaatcatc aatctcaaag acgcgattga
   107461 aatcaaagaa aaagtccaag attaattgcg tacactcgat tccaagactc acaagaaaac
   107521 taaaaagaag gacctttttt gttttccgca aatttgaaaa tagataaagg agttggaaaa
   107581 tcagaggaaa aaacaagaag acattgagga tattttgtaa aaaaatccaa cataattgtc
   107641 caatgtcact cacttcgccc agtttccaga gagaattgaa aggagtcaaa agaaaaacca
   107701 ggcgtccaag atgctgaata tctggagttc ccactcccac ggtagattgt tcttgaggag
   107761 taaagcaaaa atagacaatg caaatgctat agaaaatgac tccccagacc aaaatatgat
   107821 tataagtctt cttcatcatt aaggatttac cgctgcgact accttctggc ggtcacgttt
   107881 cattgtgtta aagcgcaatt gtccacaagc tgcgtcaata tctgtaccat gctcttgacg
   107941 aaccacacag ttgccccctt ttttcttaag cgtatcatag aaagccaaca cgcgctcttt
   108001 gggactacgg ctatattggt catgctcact aactgggtta taaggaatca agtttacata
   108061 agacaatttc ttgatgttct tgagcaattc agccaattcc aaggcttgtt ctacaccgtc
   108121 attgacttca ttaagcatga tatattcaaa ggttacacga cggtttgttg tctcaatgta
   108181 gtattcaata gcagcaaaga gtttttcaat cggaaaggca cggttaatct tcatgatact
   108241 tgaacgaagt tcattgttgg gtgcgtgaag agacacggca agattgacct gaaccccttc
   108301 atcagcaaag tcacgaattt tatgagccaa acctgaggtt gaaaccgtga tgtgacgagc
   108361 accgatagcc attcctttat catcattgat agtacgaaag aaattcaaga cattgttgta
   108421 attatcaaag ggctcaccga ttcccatgac aacgatatgg ttgacgcgtt catcctgacc
   108481 acgctcatca aagtatttct gaaccagcat gatttgcgct acgatttcac cgttattgag
   108541 gtcacgctgc ttcttaatca aaccagaggc acagaaggta caaccgatat tacagccgac
   108601 ctgagtggtc acacagacag ataaaccata gtgttgacac atgagtacaa tctcaattaa
   108661 cataccgtca ggcaattcaa agagatattt gactgtacca tcagcagact cttgcacaat
   108721 acgttgtttc aagggattga ccacaaactg gtcattgagc ttagcaatca aatccttgga
   108781 aaggttggtc atttcttcaa atgactgcac acgtttacgg tagagccatt cccagatttg
   108841 atctgcacgg aatttctttt ctccctgctc caatacccat tcctgcatgg tttgatgtgc
   108901 caaactatga attgagggtt tcatttcttc tccttattct ctactcactt ctgacgaatg
   108961 acaaaatgac gttgttcctt gtcctctttc tgagaatgct ggtctttctg acgacgtcta
   109021 tttttcttat ctgcattcga ctttcgttta gtttgagtcg gtttctttcc ttttctagaa
   109081 ggtgtttctt cttccgtctt acgcattttc ttgtcaaatg atgctcgctt aggggcttca
   109141 ttttctaaga caaaataggc acaaccataa ctacaatact ctaaaaggta gtcttgtaaa
   109201 cgactgattt tttcaagttt ttcttctgtt cggtcatcct tgtaaaaacc tcgtaggcga
   109261 agctgttcgt tgctccagtc ccccacgata taatcaaact tggttaatac ttctgaaaaa
   109321 cgctgattaa aagtcgtcac atcaaaggca tccttgatat tttcaaccaa ggaaaaagct
   109381 atcccttccg tttcgacctt gtccccgtgt aaatggaact ccggaccagg aaacttgtta
   109441 tagttgtata attcaggtgc aatttctttt cgcatagata tcctttttcc acgattactt
   109501 aatactttat tctaccataa tttctagcag ttagcacgtt tctcataaaa atgaaaaaag
   109561 tctgacgatt ttgtcagacc agaatcttat aacctaaaaa agagaagaac aattcttccc
   109621 tccaactatc attatttagc agctgcgtac aattcatcta ctttattcca gttgattact
   109681 gaaaagaaag ctttgatata gtcaggacgc acgttgcggt atttcacgta gtaagcatgt
   109741 tcccaaacgt ccaagcccaa gattggtttt ttaccttctg agattggtgt gtcttggttt
   109801 gctgttgaag tcacttcaag tttcccttct ttgttgacaa ccaaccatgc ccaacctgaa
   109861 ccaaaacgag ttgttgctgc tgcagtgaag gctgcttgga attcttcaaa tgaaccaaat
   109921 gttgcatcga ttgctgctgc cagttctgct gaaggagctg ttttctcggg agtcatcaat
   109981 tcccagaaaa gagcgtggtt caagtgtccg ccaccattgt tgataagtgc ttgacggata
   110041 tcagctggga tagattctac atcagcaagc aaggcttcaa ggtcttcacc gatttcaggg
   110101 tgtttttcta aagctgcatt ggcattgttg acataagttt gatggtgttt gtcatggtgc
   110161 aaatgcattg tttccgcatc gatgtatggt tccaaagcgt cgtatgcata tggaagttct
   110221 ggtaagataa tagccatctg taatacctct ttttctttct atatgaaaat gataacgcaa
   110281 acattcactt ttttcaagtt ttttgcttat agataaggaa atcactgaca tactttctaa
   110341 taaaataagc aaatcagcaa gaaacccacg acaagataat cctgacgcgg gttgtagttt
   110401 caacaaatgt caattgacct gactagcaat ctgtaagagt gccttttcaa aaaggaaacc
   110461 tttttcataa agacctgtct taatctgata gtctgtctca atcaaatagg aaatagcttg
   110521 cttcagaaag ctcaaagaaa gtcctctcga atctcttaat gcaaacttga tttgataagg
   110581 atttgggtta cgtcccagat aactacctaa actacttgca atctgcgatt ctgtttggcc
   110641 agactctgcc aaaatcttca cctgagtaaa agtccgaaat tgtcccagca tgactgcaat
   110701 cagtttgatt tcatcttccc cttgcaaggt caagtctctc accaaatcgc gcgcctgatc
   110761 catcttttta gtcagaataa actgagttaa atcaaaaata ttgtcctgca aggtcttggg
   110821 aattgcgtta acaatatcct cttcctcgat aacagaatcc gccttatagg actgtaaaaa
   110881 gagaagattt ttctggattt cgctaaattg aaaccccgac ttgatgagga gattttcaaa
   110941 agaatgattg gtaaactgca gaccttgttt ctgactccac ttttggaaat actggcgcaa
   111001 ttcttgttct tttacttcta ctgcatcgaa gaccttggca tcacgcttaa gtaatttgac
   111061 taaccgtctt ttgctatcca gctttccttc tgcaaagatt atcaacttgg ttgttggaga
   111121 aggattgtca aggtattcct caaatgactt aagctcatca tctgtcaaaa agcgtttctt
   111181 agcagtcgtg atatccataa aataatctaa tatcacgatt ttctcatccg caaagaaagg
   111241 aaggctgacc aactccagtt ccacatcctt gtaaactact tctttcatat caaagtaggc
   111301 aaagttgagg tcagcagaat catacccaat ctgtttcaac acttgactct tcatcacttc
   111361 aaactgaccc tgatctgtcc ctgtaaatag gctcaggctc ggtaaatttg ataaagtcaa
   111421 cttctgactt tcttcaatgg ctagcatcgt ctctcctttc ttcagatttt tcgatttaat
   111481 ttagtcaata tagcgcaatt tcccacggaa atcttctaag ctctcgtagc ctttttccac
   111541 catgattgct ttcagttcat tggtaatgcg gtcaaaagca ctgacgcctt ctttgtgaag
   111601 ggtcgttccc acctgcacca tacttgctcc acagaggatg tgttcaaagg catctcgacc
   111661 agtcagaacg ccacctgttc cgataatttg gatttgagga tttaaacgtt gataaaaggc
   111721 gtgaacattg gctagagcag tcggtttgat gtattctcca ccaattccac caaaaccatt
   111781 cttaggccga ataacgacag attcgtcttc tatatagagg ccgtttccga tagagttaac
   111841 gcagttgaca aacttgagcg gatatttgtt gaaaatagct gccgcttgat caaagtgaac
   111901 aatatcaaaa taaggtggca atttaattcc aagaggtttg gtgaagtaag caaacacttc
   111961 tgccaaaatc cggtctgttg tctcaaaatc ataggcaatc tgaggtttac ctggaacatt
   112021 tggacaggaa agatttagct cagtcagacc acgaaaatca ctctcttgga cttttttcaa
   112081 aatagtatgg gtttcctctg gagacatgcc gaccagagat aagaagaaag ttcggttcga
   112141 ctctttttcc tgcaaatcta aaagataatc caaataatag tctaagccat tatttggcaa
   112201 gcccatagag ttgatggaac caagtggaac atcttggtag cgtggctcag gattcccctg
   112261 acggaagtcc aaggtcgctg tcttagtaac aaaggttcct gccgctgagt ttttgacctc
   112321 ttctaactcc tctatcgtca tacaagccac acctgctgca ttcatcaagc aattgtcaaa
   112381 ctcaaaacca gcaatttgtg ttttcgttga taccatgatt ctaatcctcc agatttcttt
   112441 tattgctaat attataccat aattttaatt ctaggtttac tagattctgt ggttctatct
   112501 atttattcgg aaaagaaagt ctagtacaga agtcatgcta tggaaacagc tagtgtatta
   112561 gaagtttgaa caaggcttgg gtaacagact tttgaatgaa gtccaagcaa caaggagaaa
   112621 tctcaaccat gagtccattc catgactctg ttgctctaga aaaccttgca atagtcaagt
   112681 gataacgaat aaaactttgg attgaaatat ccccaagatt atctattacg aggagaaatc
   112741 ttaaccttta taatttttaa agaaatatag taaaatgaaa caagaacagg agaaatcgat
   112801 caggacagtc aaattgattg ctaacaatgt tttagaagtt gaggtgtact attctagttt
   112861 caatctacta tacatgtaaa tctctacttt cgcaaaatgg attttcagaa cagtatccca
   112921 gtatagttaa aaactataaa aaagagagga cgttcccctc ttaaaatctt attttactgc
   112981 ttctttcaaa gcatctacct tatccaaacg ttcccatgga agatcaatat ctgtacgtcc
   113041 catgtgaccg taagccgatg tttgacggta aattggacgc ttgaggtcca gcatttggat
   113101 aatccctgca gggcgaaggt caaagatttg acgagccgct ttttcaagtt gactttcagc
   113161 tactgttcct gtaccgaaag tatcgatacg aacagaaaca ggttgcgcaa caccgatagc
   113221 ataggccaac tgcacttctg ccttcttagc aaggcctgct gcaacgatat tcttggcaat
   113281 atagcgagcc gcataagagg ctgaacgatc caccttagtc gcatctttac cagagaaggc
   113341 accaccacca tgacgagagt agccaccata agtatctaca ataatcttac gaccagtcaa
   113401 acctgagtcc ccttgaggac caccgattac aaaacgacct gtcggattga taaagaattt
   113461 tgtcttatca tcaagataag aagatggaat aacttctttg atgaccttgt caatcacatc
   113521 ttgatggatt tgttcattag tggcctctgg atcatgctga gtagaaataa cgactgtatc
   113581 tacacgtacc ggacggtcat tttcatcgta ctcaactgta acttgtgatt ttgcatctgg
   113641 acggagatag ctaatttctc cagacttacg aagttctgcc agacgacgaa tcaatttatg
   113701 actgagtgca attggcaatg gcataagctc ttctgtttca tctactgcaa atccaaacat
   113761 gagcccttgg tcacctgctc caatcaagtc cagtggatct tgatcagcat ttccacgaac
   113821 ctccaaggct tcgttaacac cttgagcgat gtcaggagat tgttccacca aagatgggtg
   113881 tactcccacc gtctcagcag aaaatccata ttctgtattg gtataaccaa tctctgaaat
   113941 ggtatcacga accacacggt taatatccac ataggcattt gtagaaattt caccaaaaac
   114001 gtggacagaa ccagtatata cagctgtttc agcagcaacg tgcgcctctg gatcctttgc
   114061 taaaatagca tccaaaatcg catctgaaat ttggtctgca atcttatccg gatgcccctc
   114121 agatacagat tcagacgtga ataatttacg ctctgacata aaaatgtccc cccttaaaaa
   114181 atattgttat agagttacaa agtactgata ggaaaactct tcgtaataaa tacctaccat
   114241 cttatcggga ctatataact ttatcattat accattttta atcgcaattt gcagtcttta
   114301 atgtagtatt tcggtttaga tagttcgttc tcataaagca aaaagttgga gctcagtact
   114361 ccaacaattt ctattaaaat gtttgacgtt tagctttacg ctctgcacga ccgcgagcgc
   114421 gattttcagc acgcttggtt ttacggcgct tttcatcaac cgcccattga attttcttct
   114481 tataacccgg tttgactttt ttctttttct ttttaaccaa accaatcatt tcgatatcaa
   114541 gtttatcttg ttttttctca cggttggcac gacgatcacg gtcataggta tcttgaaatt
   114601 ccccgtcttt gaccatctta ggactaaact tgattcccaa tttctccaac tcacggatat
   114661 ccgagtcatc acttggctga taaagggtaa tagctgtacc tggtaggcca tttcgtccag
   114721 tacgaccaac acggtgaaca aaaaaagata agtcttgcgg aatggcatca ttgatgacat
   114781 ggctgacacc ttcaatgtca atcccacgtg ctgccaaatc tgttgcgaca atatactcaa
   114841 aatccagatt ttgcacctga ttcatgattc gcttgcgttc acgaggggca atatcgccat
   114901 ggatttttgc aaccttcaag ccttgagcag tcagatatga atgcaattca tcagcacgcg
   114961 ttttagtgtt aacaaaaatc attgccaaat acggctgcat caactgagtc aactggtaaa
   115021 tttgagcatt cttatcatgt cccttggtcg aaatcaacca attatcaatg gtgtcagaaa
   115081 taaccgtttt ggtcttaatt ttctccataa caggattgga taagtatttt ttcaagaatg
   115141 gttgcagttt ttgtgggata gtcgctgaga agaccatgaa ttgcaagtct tttggaagac
   115201 tgccagcaat cttatcaaca gtttccaaga atcccatatc caaggtcata tccgcttcat
   115261 caacaacaaa tgtcttggct ttatgaatag ctaaatcacc agatttaacc aagtcgtaga
   115321 tacggcctgg tgttccaata acaatatgag gctgattgct tgccaatttc tcaatctggc
   115381 gagccttatc cgtaccaccc acataattaa ccacacgaac ttcgacatct gagtgagctg
   115441 aaatctgacg cgctacttgg taaatttgag tagccaactc acgactcggt gcagtaatca
   115501 ctgcttgtac actatcgcta gcttcatcta attgctggaa aatcggtaac aagaaagtat
   115561 gagtcttacc tgaacctgtt tttgattctc ctactaggtc acgacctgcc aaaacaatag
   115621 gaatcaactt gtcttgcacc tctgttggag ttgtaaattt taactcctcc aaggcttctc
   115681 taatatagtt tttaaattga aatttcgtaa atgacataac atcctcgatt ctatctatct
   115741 tatcaattat accatatttt attccattac agtagtctca cttatttagg ctatttccag
   115801 tagcttctct agtaagaaaa ggctggaatt ttatagttcc aacctctttt cagttattat
   115861 ttccagttta acatagcatt caagccatag tgatcactca cttgtggact cttgttacca
   115921 tcaaatacga catgtaaatt ttccaccgct aactctttgg tagtaaagac ataatcgatt
   115981 cgaaggggtt cagtgttccc tttccagcca tcaatttcag gcggaacagt atagctacca
   116041 cttttctctt gagcaacttc aaatgcgtct tgtaagccta atggactagc taaaatagct
   116101 tggtaacctt cctgacctgc tgggttgtta aaatctccag ctagtaaaag tggcttgttc
   116161 aattttttca agacagcctc aaatcgtgcc cattcttctt gaaaaccttt atcccaccaa
   116221 gagagatgaa cactggcaac tgctagctcc ttgccatcga ctacagtttc agctagggca
   116281 acacggcgag tatgatagtc tgttggatca tccacatctg aaaccaaaat ttctctggct
   116341 tcaataggtg ttttagacaa gatagccaca ccttcgtggt agcggtcata gccgatatgg
   116401 ttataggccc aggtccagta gtaatttttc ccttgctcag ataacttttc aaccaagagt
   116461 ctaacatagt gatcttggtg aataggctca gctgctggca aagcttgata aaggtcatta
   116521 acctccacct ctgacgaggt catctcctga ttaatttctt ggaaacaaat caaatcatag
   116581 tccttttcaa gaatatcttc aagcaaaatc tggaattttt cctctgcttc tttctccatc
   116641 caactatgag tattgagtgt taaaaatttc attcttttct cccaaaataa gaggttggaa
   116701 tacagcttcc aacctcaagt atattacaat tctactttag caactgctgt tttagctgca
   116761 agagaacctg ttttttctaa tttaactgat ttaattgcat caccatttgt gaagacaact
   116821 actgttgaag tttcacgtcc tgctgcacgg atagcattca agtcagctgt aacaaggaga
   116881 tctcctgctg caactttttg tccttcagca acatgaactg taaatggttt accttcaaga
   116941 cttactgtgt ccaaaccaat gtgaaccaat acttcaagac ctgcttccgt cacaatacca
   117001 aaagcatgtt ttgttgggaa gatgcttgat acagtacctg aaactggaga tacaatgttt
   117061 ccatttgcag gttctactgc aaatccatca cccatcattt tttgagcaaa tactggatcc
   117121 tttacttgtt ccaaagcaac aacttgaccg tctgctactg agtaaacttc ctcagtaaga
   117181 tctttgaagt gaacagtgtt ttgttgtact tcagtcattt ggcttggaag agtttcagga
   117241 atgatttcac ctgaatcaag gatatcttgg atatcagatt tcaaaatgtc agcttttgga
   117301 ccgtagatag cttgaacccc ttgtcctttc atcacaagac ccatagctcc ttctgctttc
   117361 cattgctctg catttcctac tttatctgca tctttaacag ttacacgaag acgagtcata
   117421 catgcatcaa catcaacgat gtttacacgt ccaccaagaa ggttgataat gtttacagct
   117481 tgagagcctg ctgcaacttt cacttcgctg ctggtttctt ctgaaccttc agcagtttcg
   117541 tagtttccgt tgcgccctgg agttgcgtag ttgaattttt gaatcatgaa gtttgcgata
   117601 aagtacatga ttacagcaaa gagaacagtt acccaaacga agttaacgat atccatacca
   117661 ataccagcac tgattgcaat aggtgtacga gtcaagaact cgattgaacc gaatgagtgc
   117721 atacgtaggt ttacgacgtc agccatagcg aaggcagcac cttgaacaag tgagtaaaca
   117781 agatacatag gtgttgcgat gaacatgaac atgtattcga ttggttcagt aacccctgtc
   117841 aagaatgttg caagagctgt tgcaatcatc atacctttgt atttatgttt cttgtcagca
   117901 tcaacattac ggtagatagc aacaatcaca cccatcaaga taccgaatga accgatcatt
   117961 tgtccaactt tgaaacgagc tggatgtact gtatctaaca agtgttggta ttgactagca
   118021 tcagtacctt taaggtttac aaggtctgtt acccatgcaa gccatagtgg gtcttgaccg
   118081 aatacttgag tacctttagc tgcaccagtt aaaatgtcat aagtaccacc aagagctgtg
   118141 tagttcattg ggatagtcaa catgtggtga agaccaaatg gcaagagcaa acgttccaaa
   118201 gtaccataca agaatggtgc aagaattgga gcagtttctt gtgagttggc aatccagata
   118261 ccgaaattat tgatacctgt ttgaactact ggccagaaag cagcaagtag aattgcagcg
   118321 attgctgaac gaagaataac tacaaatggt acgaaacgtt tcccgttgaa gaatgaaagt
   118381 gcatcaggaa gtttacggaa gttgtagtat ttgttgtaag cagttgcccc tacaaaacct
   118441 gagataatcc ctacgaatac ccccatgttc aaggctggag cttcaagaac actgataaag
   118501 taagcagcaa ctttgattga accaccaaag aaagtagtta ccatagcatc tggatttttc
   118561 aacatatcgc ctgatacacc aaagattgta ccagtgatac ggttaatcaa gatgaaggca
   118621 agaccagcgg cgaaagcacc accagcacgt tctttagccc agcttcctcc aatggctagg
   118681 gcaaacaaaa tgtgaaggtt accgataacc ccccaaccga tttgctcaag aattccacct
   118741 gtgatgacaa gtggtgcaaa ggttgggtta atcatcacga tagacttacc gattgaaatc
   118801 atcaaaccag cagccggcat aaccgcgata actaccatca aagccttacc gaatttttgc
   118861 caaaattcga aagacaagac atttttgaat gtatctttca tcattcaaat ctcctttatt
   118921 tttatttagg caaacgtttt acgaaaacgt ttgcactttc tatgatttaa ttataccact
   118981 ttaatttttt ttgtaaaggc ttttataaaa aaattacact tttttctaaa aaatttctag
   119041 tgcgccaaat ttcaagttca aattagccat caagaagtct tctctggggg acttctttgg
   119101 aagctctttt cttctgcgca tctcttttca aaaactcttg tagcaaaaaa ggagatttta
   119161 caatctcctc ataaaagcag ctattttacc taaatcttca agaatcggcg catggatatt
   119221 cctgatccca atgaaccaat gaaaacccca atcacaaata gtagggcaat catcaacgga
   119281 ctaaataaat ctggactaat catggataga ttttgcccta ccaacgattt gttgacagat
   119341 tggtaaacaa tttgataaac aataaagacc aaaacagatg gtgcgatagc tcccaataaa
   119401 ccgataaagg ctccttctaa caagaacggt ccacggatat aactgttttt agctccgacc
   119461 aagcgcatga tttgaatttc gcgactgcgg gaaataatgg taatacgaat ggtatttgaa
   119521 atcaagaaaa ctgcgataaa aattaacaaa gcggcaatcc ctagtcccca aacacggata
   119581 aatgaagcta acttgaagag tctttctgta ttggcaccgc catcttgaac ctcagagaca
   119641 ccttcaattt ttttagcatc ttcggctata gtttttacat catttggagt gtttgcctct
   119701 acaatatagg catcatagag aggattggca tctccttcaa agattttcca gttatctccc
   119761 attatctcgg ttaatttttc atattgttct tctttacttg aaaaggtaac acttttaacc
   119821 gtagacatgt tcttcaaaga atcatatacc ttgtggtagt cattatttgt aacagtttga
   119881 ccttcttttt caattgtctg actattatct tccacatcct ttcggatata aactactaca
   119941 cggacattat tttcaatatc tgtagctagt ttcgctgtat tgaaaataac agatgcaaat
   120001 attgccacca aggtcaaagt aatcatgact gaactgacag cagctactgt catccaacca
   120061 tttcgtttca aactttttaa ggcttcaaat aaatggcgaa aaaatctact aatcatcgta
   120121 tccatactct ccttttgatt cgtcacgaac gacacggcca ttttcaatgg caatgacacg
   120181 gtggcgcaag gtatttacaa tctggctatt atgagtcgcc atcaaaatag ttgttccttg
   120241 taggttaatc cgttccaaga gattcataat ttcccatgaa ttatccggat ccagatttcc
   120301 tgttggctca tcagctatca atactttggg attatttaca attgcacgcg caatcgcaat
   120361 ccgctgttgc tccccacctg agagttcatt tgggaaagaa cgaaccttat gcttcaatcc
   120421 aaccaagtcc aaaacttcca tcactcgtct tttgatatta cggcgatttt ccccgattac
   120481 ttccatagcg taagcaatat tttcatagac agttttcttt ggtaacaatt tataatcctg
   120541 gaagacaacc ccaacactac gacgtagaag cgggatatct ttctttttga tcttaaccag
   120601 attaaaacca gcaactgata ggcttccttt atcgattttt acttcacgat acagagaacg
   120661 aataaaagtt gacttccctg ctcctgaagg tcctacgatg taagcaaatt cccccggttg
   120721 aacgctaacc gaaacaccgc gtagagcagt cgttccgttg tcgtattttt taacgacatc
   120781 tctcatttca ataattgaca tgtgagttcc tttctatctt agctaattcg ccacttgaga
   120841 taagcatcga taaaaccatc taggtcccca tccataacct tatctacctg agcaacctca
   120901 aagctagttc ggtgatcttt taccatagta taaggcgtga agacataaga acggatttgg
   120961 cttccccaag tgatctcctt tttctcacct ttgagagaat ctacctctgc agccttcttc
   121021 tcttgctcca tttgatagag cttagcctgc aacatcttca tggcacgatc tctatttcca
   121081 tactgggtac gatccactgt tgattggaca acaattccag ttggaatgtg ggttaaacgt
   121141 acacctgttg aaaccttatt gacgttttgt ccaccggcac cacctgaacg gaaggtatcc
   121201 atcttgatat catcttcacg gatttccact tcaatagtat catccaattc tggcatcact
   121261 tctacagatg tgaaagaggt atggcgacgt ttggcagagt caaatggtga gattcgcact
   121321 aagcggtgaa cacccatttc tgacttgagg agaccatagg cattaggccc ttcaaatgat
   121381 aaagttaccg acttaatacc agcctcatca cctgcttggt aatccaacac ttccacttta
   121441 aagcctttag cattaccata acgagtatac atacgaagca acatatcacc ccagtcctgc
   121501 gcctcagtac caccagaacc tggatggatt tccaagatgg cattgttgtg gtcataaggt
   121561 tctgacaaga gtagagtcat ctcgtagctg gtcattatct tatcaagttc ggctaactgc
   121621 gctaccagtt catcatgcac tgactcgtct tcagccaaaa aatccaataa aatttcgact
   121681 tcatcctgca actcttccat cttatggaag gtattgtaag tgttttttaa ttcatttaat
   121741 tcttgcgacg ttttttgggc cgcaatatta tcgttccaaa aatcaggttc tgtcatcttg
   121801 ttttccaaga tggcaatctc ttcctctagc ccttcgaggt caaagagacc ccctgaaaga
   121861 agctaatttt tcacgatttg cgtcaatttt ctgacgaatt actgaaatgt ccataaatac
   121921 tcctttttta cattatttca ttatagcata ttttatcatt tctttccatc tttttctcta
   121981 atcccctttt catgaaaaaa gaagcctttg ggcttccctt cttacaagac ttttgctgaa
   122041 gtgcgagcga tttcttccac ttgaatacca tttgcttcaa atttttcttt caaggctggt
   122101 aaatcaattg atccatcgat ttgcacttcg ataatcacct taccatcctt acgcggaata
   122161 ttgactgtat gggagatatt caaattttct tctacaatca aagaaacaat ttttccaaga
   122221 acaccaactt catcttctgt aacaaagcgt acacgaatcc cttcttcgcc ataacctgca
   122281 atttcaagaa aggcttggaa aacgtcacgg tcagtaataa ctccgtatac ttgatggtta
   122341 tctacgacag ggagaatact aatcttattt ttcaacatca gataagttgc atcttctaga
   122401 ctagcatagc ctgagacagt gacaacatcg cgaatcatga catcttttac ttttgtctta
   122461 ttcagaagat aattcatctc atagatagaa agacttgttg ctttagatgg acttgcttgt
   122521 gcaatggttc cctcagtcac caaaccaact aattgatcat tttcgataac aggcagacgg
   122581 tgcaaacctt gctctctcat caaatctgct gcatgagata ctgttgtatc tggactaata
   122641 taaactacct tgcgggtcat aaaatcttta actgccatga gacttctcct tttctattct
   122701 tatccctatt atacaatctt tttgtaaatc tatcaaacgc ttacatttct ttttcgaaat
   122761 tcagaaaagt atgaataagc tagcaaaaag agctctgaaa tcgagctctg tgaatgaagg
   122821 taagaaattt ttcattcgat tttttcaatt attagaaatt aagctttcaa tgtagatgca
   122881 gatttgtttg caatctcaat ctaccgacta aaaaggtccc ccggactata ttgatgatta
   122941 cttcgtaatc tccatctgcc gactaaaaca atccactgga ttgttttagc cacctagata
   123001 tgcttttctg acttcttctg atgaagcgag ttcttttcct gttcctgata ggacgatttt
   123061 ccctgtttcc agtacatatc ctcggtcaga gattgcaagt gctttattgg cattttgttc
   123121 aatcaagagg accgttgttc cttgcttctg aatatcttga atgatatcaa aaatttcttg
   123181 gataaagatt ggggcaagtc ccattgatgg ttcatctaaa agaagaagtt ttggtgttga
   123241 catgagggcg cgtcccatgg caagcatttg ttgttccccc cctgaaagag tggctgcatc
   123301 ttggttcttc cgttcttcaa gacgaggaaa gcgtgagaaa accttcttca agttagcttg
   123361 attttcttca cgatttttct ttaagaaagc tcccatttca agattttcca taacagtcaa
   123421 gccaggaaag acgtggcgtc cttctggaac ttgtgaaaga ccacttgcca cgattttctg
   123481 agctggcatt ttttggattt cttgacctaa aaattcaatc tttcctgaac ttggtcgaac
   123541 caaacctgac aaggtgcgaa gaatagttgt cttacctgca ccgttggcac cgataaggga
   123601 aacaacttct ccttcattaa cttcaaagct tacatcacga actgcttgga tcataccgta
   123661 atgcacagaa agattttcaa cttttaacat agacattagg cttcacctcc tagataagct
   123721 tcgataacgc gtttattggt cttaatttcg tctggagttc cttgagcgat taaacggcca
   123781 tattcaagta cgtagatacg ttctgttact tccatgacca gattcatatc gtgttcaatc
   123841 aacatgattg taatcttaaa ctcatctttg atacgacgaa ttaactcagt caattcggct
   123901 gtttcctgtg ggttcatacc tgctgctggt tcatctaaga agagaatttt aggttccgta
   123961 gcaagggcac gaacaatttc caaacgacgt tgttgtccgt aggaaagatt tttagcaaga
   124021 gtctctgcat caccatctaa atcaaagatt ttcaacaatt ccaaagcttt agcctttaat
   124081 tctttttcac tcttgtaaaa agctggtaag cgtaagaaac tagtaaaaac atgctgtttg
   124141 tgatggtttc caaaagcaat caaaacattg tctaaaactg ttaaatcttt aaaaagacgg
   124201 atattttgga aagtacgtcc aagtcccaaa gaggcaatct tataaggtga tttcccattc
   124261 aaaaggtgac catctagggt tactgttccc tcgcttggtt cataaacacc ggtcaaaagg
   124321 ttgaaaaggg tggttttccc agctccgttt ggaccgatta atccaaccag ttccccttcg
   124381 ttcaattcaa gagtcacatc tccaacagct gttagaccac caaaatgttt ggttaactgt
   124441 tttacttcaa gtaatgccat tagttttgtt cctccttctt agatttttta aagaaacgtg
   124501 ataggctcag ttcccacgtt ccaaggagtc cacctggtct gaaaatcatt accaatacca
   124561 aggccaaagc gtaaataatc atacgcacac tagcaacatc ttggagaagc atattcaaaa
   124621 ttcccagaac aatagccgaa acaatcgcac ctgtaatgga accgagtcca ccaaatacaa
   124681 caataatcaa aacgttgatt gagttgatga aggtgtaatc tttcggtaca acagacccga
   124741 taaatcctgc ctgaagtgac ccagcaatac ttgcagtaat ggcaccaaag acaaaagcga
   124801 tgattttaat tttagtcgta ttaaccccaa ctgactcagc agcgatttca tcttcacgaa
   124861 cagagagggt tgaacggcca attgggctac gcaagaagtt caaggttgca atggttgtaa
   124921 tcacgacaaa gaagtaaacc atttgccaag ttgtaaagtt aggaatccct aagatacctg
   124981 ccgcaccatt tgtaagactt ccaccattga tgataaagat acggataatt tcagaaacac
   125041 ccagagttgc taccgcaaga tagtccccct tcaagcgcaa ggttggaatg ccgacaagta
   125101 aggcaactgc tcctgaaagc aaagccccta caagcatagc tccaaagaag gcaccgtagg
   125161 ttggtgattt agaaccaata atagctgctg cataggcacc aatcgccatg aaaccagcat
   125221 gaccaagtga aaattgtcct gaaaaaccaa cgattaagtt gagaccaaca gccaaaataa
   125281 tattaattcc aatttgttgt aaaatctgta catagaatag attaagtact ccgactgaaa
   125341 ccagtacact aatcaagcta tagccagcta acaaaaggag taaccataga atattaactt
   125401 ttaaattttc cttcatcgtt tacaccttct ctttcacatt cttaccaagg ataccagctg
   125461 ggcggacaat caagatcaac aacaagattc cataaacaat ggcatcacgg aaatctgaca
   125521 tcccaaaggc tgtcgcaaag gtttccaata gaccaatcac aaagccacca agagccgcac
   125581 caggaataat tccgatacca ccaagtactg cggcaacgaa agatttaaga cctggagtaa
   125641 cccccatcaa aggctcaaga gagttataat aaagagcaat cagaacacca gccgcacccg
   125701 caagagcaga acccaaagcg aaggtaaagc taatcgtacg gtttacattg atccccatca
   125761 attgtgccgc gtcgctatct actgatactg cacgcatggc tttccccatc ttagtctttt
   125821 ggacaatgac ttgtaacaaa atcatcaaaa tcaaggaaat ggccaaaatc attaactgca
   125881 catttgttaa gctaattggt cccaaatcat atcgaactgt ttgaatcgct tgagggaagg
   125941 cacgggtatt ggcaccaacc agatagacca ttccatactc caataggaaa gaaaccccaa
   126001 tagccgtaat caaaacagca atacgagtag agtggcgcaa aggtcggtaa gcaagaaact
   126061 caatcacgac accaagaata gctgtcgcta gcatagctac aataagcgct acaaagaaat
   126121 tcatttggaa agaattgatc aagaaataac cgataaaggc tcccatcata taaatatcac
   126181 catgggcgaa gttgatgagc ttgataattc cgtaaaccat ggtatatcct agggctaaca
   126241 gcgcgtaaac actacctaga atcaaaccat ttacgagttg ttggagcata agattcactc
   126301 tttctattta taattccgag ggttttccct cactttttga taggttctta tactcaatga
   126361 aaatcaaaga gcaaactagg aaactagccg caggttgctc aaagcactgc tttgaggttg
   126421 tagataagac tgacgaagtc agtcacatat ataatccaag gcgacgttga cgcagtttga
   126481 agagattttc gaagagtatt aaatatcgaa acagggagtg agtcaaaggc tcattcccta
   126541 tttcaacatt tttctattat ggttttacaa cttctgctgc ttcaacttta ccattgttca
   126601 tggtcatcat gtaagcagtt ttgactgtgt tgtggtctgc atcgaagctt gtttgaccag
   126661 ttacaccttc aaaatctttt gttttagcaa ggttatcctt gatttcacct gaatttttag
   126721 caccttttgc tgcgtttgct acaaggtgaa ctgaatcata agccaaggct gcaaatgttg
   126781 aaggctcttc attgtactta gcacggtaag cgtcaaggaa ggctttagct ttagctgaaa
   126841 cttctacagt agttgagaag cctgagataa agtagatgtt tgatgctttt tcagcagttg
   126901 cttgttgtac aaactcctca ccgttgaatc catcaccacc aacgattggt ttgtcaattc
   126961 ccatgccacg cgcttggttt acaattttac cagcctcatt atagtaacca ggaacaacga
   127021 tagcatcaaa gtctttccct ttcatttttg taagggctgc ttggaagtct gtgtcacctg
   127081 ctacgaaagt ttcatctgca acgatttcac ccttgtatga ctcgcggaaa gatttggcaa
   127141 tccctttagc atagtcactg gcattgtcag tgtaaagaac aactttctta gcatttaatt
   127201 tttcagaaac atagtttgag ataatttttc cttggaagct atcttggaaa gttccaataa
   127261 agaggtaatc ttgaccttta gtcaatccat cttgagtcgc acttggtgag atcaatggaa
   127321 cacctgcttt tgtagcgttc gctaccgcag ctgcagtcgc accagatgtc gcaggtccta
   127381 cgactgctga tactttagat tgggttacaa ggttagttgt aactgaagca gcctcagctg
   127441 tttcagactt attatcttta tcgattactt cgatttgttt tccatcgata ccacctgcgg
   127501 cattgatttc atcaacagcc aattgggcac ctttttgttc agctgttccg tatgcagcta
   127561 aagaacctga ttcttcaaag ttaaacccga ttttaattgt cttttcctct actgagttac
   127621 cagcagtgtt gactgctcca gacttcactt ctccacaggc tgcaagaagt gctacacttg
   127681 caagcgccac aaacgatagg gcaaattttt tcttcatctt ttttgtctcc ttatttctta
   127741 aatagtctgt taagaatata ccgaattatc agaaaattgt caatgttttc cttgaacttt
   127801 ttcgatgata acgttttcct atcgataaag attgcccaca aagggtgttt ccaactcttg
   127861 gatatgacaa accctaactt ttttaataaa tgtttccttg ctcaagcgtc cgaccaattg
   127921 ctccacttct tgagttggaa catagagttg taagtaacga tgtttcttgg aatgataggt
   127981 aatatctcca taatcctgca gttttttggc atcacgatta tagtaaagat agataatcaa
   128041 gccagagcga ttgacttttt caaacatgat aaatcctctt tctaagaaat ctctccctat
   128101 tataccaaaa aaagcaaacc cagtcgagtt tgccttctat catcattagt tcaatgaatt
   128161 gttggccata atttcatcaa taaagccata ttcaagtgtt tcctgggcgc tcatccagtt
   128221 atcacgttct gcatctgcat ggactttttc cattgactga cctgaatttt cagccaagat
   128281 tttttccaag gtattacgag ttttgagcaa gtgttctgca gcgatagcca tatcagtttg
   128341 ttgggtacca ccacctgtac cgcccattgg ttggtgaatc atgtattcag catttggaag
   128401 catgaaacgt ttgccttttg ctccacttga tgcgatgact gttcccatag atgcagccat
   128461 tcccataaca atggtttgga catctgcctt gataaagttc atggtatcta cgattgccaa
   128521 accagctgaa acagaaccac ctggtgtatt gacataaagg taaatatctt ttgtactatc
   128581 ttgggcatcc aagaaaagca attgggcaat aacagagtta gccatattgt cttcaaccgg
   128641 acctgtcagc ataatgatgc ggtctttgag aagacgtgag taaatatcgt aagaacgttc
   128701 tccacggctt gtttgttcaa taactacagg aatcattcat ttctcctttt gagttttaat
   128761 tttgttggtc aaatgactga agataagact attataatat cttggtcaaa aaaggtcaaa
   128821 tttttgctct gctttcatta gacagaaaca aaaacccaac ctcctttcgt gactggaaat
   128881 acttttccaa gtcattcttc ttttcgatct tattttgtac cgaacaagcg gtctccagca
   128941 tctccaagac ctggaacgat ataaccgtgt tcgttcaaac gttcatccaa ggctgctgta
   129001 aagatttcta catctggatg agcttcttga agggctttta caccctctgg agcagataca
   129061 aggcagacaa atttgatatt tgatgcgcca cgttttttaa gagaatcaac agccaagatt
   129121 gctgagccac ctgttgccaa cattgggtct actacaaaaa tttgacgttg gtcaatgtcc
   129181 tcaggtaatt tcaccaagta ttcaactggt tgaagtgttt cttcatcacg gtacataccg
   129241 atgtggccaa ctttagcagc tggaaccaag ttcaagagac catcaaccat cccgatacct
   129301 gcacgcaaga ttgggacgat ggccaatttc ttacctgcca attgtttttg aactgttttt
   129361 gtaattggtg tttcgatttc cacatcttct agtggaagat cacgaagtac ttcatacccc
   129421 atcaacattg caatctcatc tactagctca cgaaaagctt ttgtagaagt atctgtacga
   129481 cgcaagattg acaatttgtg ttgaatcagt gggtgattaa taacttcaat ttttcccatt
   129541 tttggaattc cttctttcaa tttattcttc ttattatacc aaaaaacggt ttaaaaatct
   129601 ttctaaacca tttatttttg ataattttta cattagatca gcctctttaa gagctgtctg
   129661 tactgtctca agtggtaaat gggtcaattc tgtccctttt tcttgataaa ggtattgggc
   129721 gtagtcgtcc attcggtact ggttgatata aaccacacgc ttgcagccga cctgaagcaa
   129781 ttgttttgta cagttgagac aaggaaaatg ggttacatag gctgtaaagc ctttgggaac
   129841 accacgctca gcaccttgaa ggatagcatt gacctcagcg tgaagggtgc gaacacagtg
   129901 gccttcaatg accaaacatt cgtgatcaat acaatgctca gtccctgaca ccgaaccatt
   129961 gtaaccagtg gaaataacct tattatcttt taccagaatc gcgcccactt tagcacgttt
   130021 acaagtggaa cgattcgcaa ttagtagggc ttgggctgca aaatactcat cccaggccag
   130081 tcttttttca gtcatctctt ttctcctttt tctctatttt ttaaaaaatg gtaaacctaa
   130141 atctgcaatc ttttcagctg gtaccttcat gccatccttg atccatttta gaaggacaga
   130201 gacgatggct gagctccaga aggaatgaag ataagagctg acaccttttg atttcccatg
   130261 gtatttttct agaaattcct gcatggcttg gacaaagatt ttttccagat ggtaatccaa
   130321 ggccaattga attactctag cttcctttct ggcctcccgg aaaaggtgaa cccaaaccaa
   130381 ataaaggtct gtctttaaat cgtaatgatg cagctgttcc ataatattgt ggacagttcg
   130441 tttaaagacg ctctctaaaa tttcctcttt ggagtcataa ttgcgataaa aggccgcacg
   130501 cgaaacacct gcacgtttga ccaattcaga aatactaatc ttggtcagtt cctttttttc
   130561 caagagttgc aagagggctg tttcaatggc ttctctggtt aataaattgg attcttggtt
   130621 tgattttctg agattttcaa gagacttttc agagattcta cgttcagaca taacattttc
   130681 tttctacttg tcacaacaga cggatgatgc ttttgtttca agggttttca tgatataatt
   130741 gtaaaaaaag acagaacctt tgtcaatgta taactgacaa agatggagaa tttctatgac
   130801 ttggaagatt attgctgact ctggttgtga ttatcgtcaa ctgccaacac cagctattaa
   130861 cacaaccttt gtaagtgtcc ccttaaccat tcaagtagct gatcaggtct ttgttgatga
   130921 cgccagtctc gatattgacc aaatgatgga aaccatgtat gcaactgcag aagcttcaaa
   130981 atcggcttgt ccaagcccag atgactattt gcgagcattt gaaggtgcca aaaacatttt
   131041 cctagtaacc atcacaggta ccctttctgg tagtcacaat agtgctcaac tagcaaagaa
   131101 tatttatctg gaagaccatc ctgacactaa gattcatgtg attgatagtt tatctgctgg
   131161 tggtgaagtt gacctactcg tagaaaaatt gaatgacttg attgaccagg gcttgtcttt
   131221 tgaagaagtg gttgaagcta tcaccgccta tcaagaaaaa actaagttgc tctttgtcct
   131281 agccaaagtc gataacttgg tgaagaacgg ccgtttgagc aagcttatcg gtacggtcgt
   131341 tggccttctc aacattcgta tggtcggaaa agctagtgaa actggaactc tcgaattgct
   131401 acaaaaagca aggggatcaa agaaatcagt tcaagctgcc tatgatgagt tagtaaaagc
   131461 tggatatgct ggtggccgta ttgtcatggc ccaacgcaat aacgaaaaat gttgtcaaca
   131521 gctctcagag cgaatccgtg aaaccttccc acaagcggat attaaaattc taccaacctc
   131581 tggtctctgc agtttctatg cagaagaggg cggtttgctg atgggctatg aaattgatta
   131641 attgcattct tgacaagagg tgaccatcat ctcttgtttt tttgtggtac aatagagcta
   131701 tgaaacattt tgatactatt gtcatcggtg ggggacctgc tggtatgatg gctacgattt
   131761 ccagtagctt ttatggacag aaaaccctcc tcatcgaaaa aaatcggaaa cttggaaaaa
   131821 aattagctgg gactggtggg ggacgttgca atgtgaccaa caatggtagc ttagacaacc
   131881 tgctagctgg aattcctgga aacggacgct ttctttacag tgttttctcc cagttcgata
   131941 atcatgacat catcaacttt tttacagaaa atggtgttaa acttaaggtc gaagaccacg
   132001 gacgcgtctt tccagccagt gacaagtctc ggactattat cgaagctttg gaaaagaaaa
   132061 tcactgaact aggtggtcaa gttgctactc aaatagaaat cgtttctgtt aaaaaagtag
   132121 atgaccagtt tgtccttaag tcagcggatc aaaccttcac ttgtgagaaa ctcattgtca
   132181 caacaggtgg taagtcttat ccttcgactg gttcgactgg ttttggtcac gagattgctc
   132241 gccattttaa gcataccatc accgagcttg aggctgctga aagtccttta ttaacagatt
   132301 ttccacataa agccttacaa gggatttctt tggacgatgt gaccctaagt tatggtaagc
   132361 atgtcatcac tcatgattta ctctttaccc actttggttt gtcaggtcct gctgccctac
   132421 gcatgtctag ctttgtcaaa ggtggggagg ttctctcact cgatgttttg cctcaacttt
   132481 ctgagaagga cttggttaca tttctagaag aaaatcggga aaaatccttg aaaaacgctt
   132541 taaaaacctt gttaccagaa cgcttggccg aattttttgt acaaggatat cctgaaaaag
   132601 tcaaacagct gactgaaaag gaacgagaac aacttgtcca gtccattaaa gaacttaaaa
   132661 ttcctgtaac tggaaaaatg tcccttgcaa agtcctttgt taccaagggt ggagtcagtc
   132721 tcaaggaaat caatcctaaa acccttgaaa gtaagctggt acctggcctc cactttgcag
   132781 gcgaagttat ggatatcaat gcccacacgg gtggctttaa catcacttct gccctctgta
   132841 ccggctgggt ggcgggaagt ctgcattatg attaaagatt aaaggttgtg aagaatgaac
   132901 agaagagagg cagtcgaatt tgttaacatg tgtatgatta aaaacggaga taaggtcctg
   132961 gtccaagacc gagttagtcc cgactggtct ggcattactt ttcctggtgg tcatgttgaa
   133021 cgtggcgaat cctttgtcga tgctgtcatt cgtgaagtga aagaagaaac tggtctgatc
   133081 atttccaaac cccaactctg tggtatcaaa aactggtatg acgacaagga ttatcgttat
   133141 gtcgtccttt tttacaagac agaacacttt actggtgaac tccagtcttc agacgaaggg
   133201 aaagtttggt gggaggactt tgaaaatctt tctcatctaa aacttgcaac cgatgatatg
   133261 tctgatatgc ttcgtgtgtt tctagaagaa gatctcagtg aattctttta ctacaaaaac
   133321 ggtgacgact ggctttatga tttgaagtaa aaaataggct aggaaattcc tagcctattt
   133381 tttctgcatt tgtctgaacg taagccgcaa tggcatctga cgtgtactgg gctgttccag
   133441 aaccaaactt gtcaatgttt tccttaaact ctgggttgta gacgtaacct ttaccgatat
   133501 gaccgaatac ctcaatagag cagtcaaatc cataagtgcg aatggcttgc aagagcttgg
   133561 ctgcttgctc ttggttttcg gttgctgttg caggtaaacc agcttgaaga ttttgtgcca
   133621 aagtttgaaa gacttggtta aaggcggccg tagcctcgtt ttcgtgacct ttttggcgtt
   133681 caagcgcttg tcccatgact tcttgaccat atttctctac cgcttcttgg tggtattttt
   133741 gattgtcttg atagctaaat cccgtgaatt tttcctcaat ggtcattttt ctttctcctt
   133801 tttgttcttg aatagttttt tgcaaggtgg aaatcaaggt atccagatgt tgcctttcgc
   133861 gagttagata gtccaactgc ctagttaaat ggggcaataa atctgtcctt tcttccttta
   133921 acagctctgc tattttctct aaagaaaagc ctagatattt gtagtaaaga atgacctgaa
   133981 ggcgttccaa atcctcttga ctataggttc gatagccgtt ttccgacttt aaggggacca
   134041 agagtcctat cttgtcatag tgatgcaggg cagggtcttg acagagacac ctgaaagctg
   134101 cgcagcttct tttatatggt acatgatttc ctccttacaa tgatagtata acccctcccc
   134161 ttaggtcaga gtcaagcgtt tttgagaaag gtgtgaaaac ttgaaaatgg tttgcttgac
   134221 agaccttaga aaacataata ggatagtcaa gtctatcaat caaacagaag gctatttgac
   134281 aactcaagta gctttttctt attttgaaaa aggagatcag agtttaacta tgtcagaaaa
   134341 atcacaatgg gggtcgaaac ttggttttat tctagcatct gctggctggc catcgggctt
   134401 ggttccgttt ggaagtttcc ctacatgact gctgctaatg gcgatggagg ctttttacta
   134461 atctttctca tttccactat tttaatcggt ttccctctcc tgctggctga gtttgccctt
   134521 ggccgtagtg ctggcgtttc cgctatcaaa acctttggaa aactgggcaa gaataacaag
   134581 tacaacttta tcggttggat tggcgccttt gccctcttta tcctcttatc tttttacagt
   134641 gttatcggag gatggattct agtctatcta ggtattgagt ttgggaaatt gttccaactt
   134701 ggtggaacgg gtgattatgc tcagttattt acttcaatca tttcaaatcc agccattgcc
   134761 ctaggagctc aagcgtcctt tatcctattg aatatcttca ttgtatcacg tggggttcaa
   134821 aaagggattg aaagagcttc gaaagtcatg atgcccctgc tctttatcat ctttgttgtt
   134881 atcatcggtc actctctcag cttgtcaaat gccatggaag gggttcttta cttcctcaaa
   134941 ccagactttt caaaactgac tagcgctgat ctcctctatg ctctgggaca atctttcttt
   135001 gccctctcac taggggttac agtcatgttg acctatgctt cttacttgga caagaaaacc
   135061 aatctagtcc agtcaggaat ctccatcgta gccatgaata tctcgatatc catcatggca
   135121 ggtctagcca ttttcccagc catgtcagcc ttcaatatcc agtctgaagg gggacccagc
   135181 ctgctcttta tcgtcttgcc tcaactcttt gacaagatgc cttttggaac cattttctac
   135241 gtcctcttcc tctttgcgac tgtcacttct tctgtcgtga tgctggagat caatgtgggc
   135301 aatgtcacca accaggataa cagcaaacgt gccaaatgga gtgttatttt aggaattttg
   135361 acctttgtct ttggcattcc ttcagcccta tcttacggtg tcatggcgga tgttcacatt
   135421 tttggtaaga ccttctttga cgctatggac ttcttggttt ccaatctcct catgccattt
   135481 ggagctctct acctttcact ttttacaggc tatatcttta aaaaggctct tgcaatggag
   135541 gaactccatc tcgatgaaag agcatggaaa caaggactgt tccaagtctg gctcttcctt
   135601 cttcgtttct tcgtttcgtc attccaatca tcatcattgt ggtcttcatt gcccaattta
   135661 tgtaatcaaa aagaacttga gtagtgaact caggcccttt ctttttatgg atggctaaca
   135721 atcaattcca aaccttgccc ttccagagtc caagcttcaa catcacttgg taggataaag
   135781 tggctgcctt tttgaattgg ataatttttc ccgtcaacag ttagctgacc ttgaccagct
   135841 aagacactca ataaactgta gtcagctgtc ttttcaaagt caacttttcc agtaatttcc
   135901 cacttgtaaa ctgcgaagaa atcattagat acaaggagag tggaacgcaa atcatctgct
   135961 ttaacagtta caggacggct atttgctggc tcaccaatgt tcaagacatc gatggatttt
   136021 tcaagatgaa gttcacgcaa gttgcctttg tcatccttgc ggtcaaagtc atagacgcga
   136081 taggtggtat cgctagactg ctgggtttca aggattaaga tacccgcccc gatagcgtgc
   136141 atagtcccgc ttggtacata gaagaaatct ccagccttaa cagggacttt ggtcaacaag
   136201 tcatcccagt tcttgtcctc gatttgctgg cggagttctt cttttgactt ggcattgtga
   136261 ccgtagataa tctctgaacc ttcatccgct gcgataatgt accagcattc tgtttttccg
   136321 agttcgcctt catgctcgag tccataagca tcgtctgggt gaacttggac actgagccag
   136381 tcgttggcat cgaggatctt ggtcaaaagt ggaaatacag gttctggacg attgccaaat
   136441 aattcacggt gttccgcata caaagtagca agatctgttc cctcgtaacg accatttgca
   136501 actttagaga ctccatttgg atgggctgag atggcccaat attctccgat tttttcactt
   136561 gggatgtcgt agccaaactc atcacgtagc ttggctccac cccagatttt ttcttgcata
   136621 actgattgta aaaataatgg ttctgacatg tcgatctcct gtctgatttt tctcccctca
   136681 ttatagcaaa aaaagagttc gaattgaact cttttttaca tcttataaag cagggagaag
   136741 attttataaa aatagtaaac aaatgtgctc tacccgatgc ttgcaccatt gctatcaatg
   136801 acatccttgt accaatagaa ggacttcttc ttgctacgtt tgagagctcc gtttcctaca
   136861 ttatctcgat ctacatagat aaagccatag cgcttattca tttcccctgt gccagctgaa
   136921 actggatcga tacagcccca agtcgtataa ccaagcaagt caaccccgtc ttggtaaatg
   136981 gcatctcgca tggccttgat gtgggcctct aagtaagtaa tccgatagtc atctgctaca
   137041 taaccattct catccggtgt atccatagca cctagtccat tttctacgat aatacta
//
LOCUS       DAVKBC010000002        89247 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVKBC010000002 DAVKBC010000000
VERSION     DAVKBC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 89247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89247
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.002"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            659..1651
                     /locus_tag="VWX64_000147"
     CDS             659..1651
                     /locus_tag="VWX64_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9189716.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1653..2471
                     /locus_tag="VWX64_000148"
     CDS             1653..2471
                     /locus_tag="VWX64_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU9189717.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2473..3258
                     /locus_tag="VWX64_000149"
     CDS             2473..3258
                     /locus_tag="VWX64_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9189718.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLIFFVISLKLWDKGLDSYESAGS"
     gene            3297..3575
                     /locus_tag="VWX64_000150"
     CDS             3297..3575
                     /locus_tag="VWX64_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU9189719.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3512..3757
                     /locus_tag="VWX64_000151"
     CDS             3512..3757
                     /locus_tag="VWX64_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9189720.1"
                     /translation="MSRRKKAYQGRKIGSQLFATLESEARKKVGYLQVKTVAEGSNKD
                     YDRTNDFYRGFGFKKLEIFLQLWNPQNPCQILIKKLE"
     gene            complement(4138..4224)
                     /locus_tag="VWX64_000152"
                     /pseudo
     CDS             complement(4138..4224)
                     /locus_tag="VWX64_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4445..10864
                     /locus_tag="VWX64_000153"
     CDS             4445..10864
                     /locus_tag="VWX64_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU9189721.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSNSEDALSISDKEKV
                     AENKEKHENIHSAMETSQDFKEKKTAVIKEKEVVSKNPVIDNNTSNEEAKIKEENSNQ
                     SQGDYTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSSLKNTKVLYTYDRIF
                     NGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAGSTSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHF
                     IRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLF
                     NIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGT
                     DLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKATK
                     YDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKSEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRALSETTIYADSRNVEDGRSTQSVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKFNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPIYKGELEKGYQFDGWKISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
     gene            11491..11967
                     /locus_tag="VWX64_000154"
     CDS             11491..11967
                     /locus_tag="VWX64_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9189722.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            12005..12310
                     /locus_tag="VWX64_000155"
     CDS             12005..12310
                     /locus_tag="VWX64_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9189723.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            12358..13833
                     /locus_tag="VWX64_000156"
     CDS             12358..13833
                     /locus_tag="VWX64_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU9189724.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            13856..13933
                     /locus_tag="VWX64_000157"
                     /pseudo
     CDS             13856..13933
                     /locus_tag="VWX64_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14183..20884
                     /locus_tag="VWX64_000158"
     CDS             14183..20884
                     /locus_tag="VWX64_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU9189725.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDTKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRIYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(21132..21988)
                     /locus_tag="VWX64_000159"
                     /pseudo
     CDS             complement(21132..21988)
                     /locus_tag="VWX64_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(22199..22558)
                     /locus_tag="VWX64_000160"
     CDS             complement(22199..22558)
                     /locus_tag="VWX64_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU9189726.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLTLSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            22650..23606
                     /locus_tag="VWX64_000161"
                     /pseudo
     CDS             22650..23606
                     /locus_tag="VWX64_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            23590..24147
                     /locus_tag="VWX64_000162"
     CDS             23590..24147
                     /locus_tag="VWX64_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9189727.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            24140..24394
                     /locus_tag="VWX64_000163"
     CDS             24140..24394
                     /locus_tag="VWX64_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189728.1"
                     /translation="MDKQYLREKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            24406..26460
                     /locus_tag="VWX64_000164"
     CDS             24406..26460
                     /locus_tag="VWX64_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU9189729.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            26639..27499
                     /locus_tag="VWX64_000165"
     CDS             26639..27499
                     /locus_tag="VWX64_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU9189730.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            27718..28428
                     /gene="ccdA2"
                     /locus_tag="VWX64_000166"
     CDS             27718..28428
                     /gene="ccdA2"
                     /locus_tag="VWX64_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9189731.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            28448..29014
                     /locus_tag="VWX64_000167"
     CDS             28448..29014
                     /locus_tag="VWX64_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU9189732.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            29025..30137
                     /gene="msrB"
                     /locus_tag="VWX64_000168"
     CDS             29025..30137
                     /gene="msrB"
                     /locus_tag="VWX64_000168"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9189733.1"
                     /translation="MNDKLKIFLLLGVFFLSITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKTVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            30405..31142
                     /locus_tag="VWX64_000169"
     CDS             30405..31142
                     /locus_tag="VWX64_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9189734.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            31139..32830
                     /locus_tag="VWX64_000170"
     CDS             31139..32830
                     /locus_tag="VWX64_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9189735.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRVETS"
     gene            32946..33509
                     /locus_tag="VWX64_000171"
     CDS             32946..33509
                     /locus_tag="VWX64_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU9189736.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            33531..38966
                     /locus_tag="VWX64_000172"
     CDS             33531..38966
                     /locus_tag="VWX64_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9189737.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPSPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETVNQPVEQPKVETPAVEKQTEPTEEPKVEVTSIPQTTRYEEDLTKE
                     HGTREVVKEGKNGSRTVTTPYILNATDGTTTEGTSTTDEAEMEKEVVRVGTKPKEKLA
                     PVLSLTSVTDNAMLRSARLTYHLENTDSVDVKKIHAEIKNGDKVVKTIDLSKERLSDA
                     VDGLELYKDYKIVTSMTYDRGNGEETSTLEETPLRLDLKKVELKNIGSTNLVKVNEDG
                     TEVASDFLTSKPVDVQNYYLKVTSRDNKVFRLTVEKIEEVTEEGQPLYKVTAKAPNLI
                     QHTDATKMQDEYVYYIEKTRATDGDIYYNFNDLVNAMNKNKTGTFKLGADLNATGVPT
                     PAKSYVTGDFRGTLTSVDGEHYTIHNTSRPLFNNIIGGTIKDINLGNVNIHMPWANNV
                     ASLANIIKGGTTIENVKVTGNVLGKDWVSGFIDKIDSGGTLRNVAFIGNVTSVGTGGS
                     FLTGIVGENWKGLVEQAYVDANIRGKKAKAAGIAYWSQNGGDNYAVGRYGAIKKSVVK
                     GSIDVEKPIEVGGAVGSLNYLGYIEDTVAMMKVKNGEIFYGSHDIDTDPYYTGERVNR
                     NFIVDGVSEGKSSYKYSKQQNRIKSVSQEEADKKIKELAITADKYAITEPIVNKLNAL
                     TTRDNEYRTTQDYKADRELAYRNIEKLQPFYNKEWIVDQGNKVPSNSKLLTTEVLSVT
                     GMKDGQFVTDLSEIDKIMIHYADGTKEEMNVTAVADSKVKQVREYDVTDLGVVYTPNM
                     VDKNRDQLIADVKAKLSSVELISPEVRALMDKRGKAEENTEGRQNGYIRDLFLEESFA
                     EVKAGLGKLVKALVENEDYQLNSDEAAMRALIKKVEDNKAKIMMGLAYLNQYYSFKYA
                     ELSIKDIMMFKPDFYGKNVNVLDFLIKIGSSERNVKGDRTLEAYRETIGGTIGINELN
                     GFLHYNMKLFTNHIDINDWFKKAIEKNAYVVEQPSTNPAFANKKYRLYEGINNGQHGR
                     MILPLLNLKNAHLFMISTYNTISFSSFEKYGKDTDEKREKFKSEINKRAKEQVNYLDF
                     WSRLATDNVRDKLLKSQNVVPTPVWDNHNSPNGWASRHGHIDGKPDYAPIREFFGRIN
                     KYHGYKYGYGAYAYIFAAPQPMDAVYFVMTDLISDFGTSAFTHETTHINDRMAYYGGH
                     WHREGTDLEAFAQGMLQTPSVSNPNGEYGALGLNMAYERQNDGNQWYNPNPNKLKSRA
                     EIDHYMKNYNEALMMLDYLEAESVLPKLKGNNDRWFKKMDKQMRKDGQPHQFDKIRDL
                     NNEEKKIQLASIEDLVDNNFMTKHGAPGNGTYNPSDFSSAYVNMNMMTGVYGGNSSDG
                     APGAASFKHNTFRMWGYFGYENGFIGYASNKYKAEANKAGQTLSDKYIINKVSGGTFN
                     TLEAWKKEWFKQIKTKAQKGFTAIEIDGKTIDSYEKLKDLFDKAVEEDLKGTGTDKTV
                     KLKEKVYKQLLKNTDGFSGDLFTAPQA"
     gene            39035..40756
                     /gene="pabB"
                     /locus_tag="VWX64_000173"
     CDS             39035..40756
                     /gene="pabB"
                     /locus_tag="VWX64_000173"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU9189738.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVAEVADLLAQVESYQ
                     EQDYYVVGYVSYEAAPAFEEKLAVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAENYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLGQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            40757..41374
                     /locus_tag="VWX64_000174"
     CDS             40757..41374
                     /locus_tag="VWX64_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9189739.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGATLTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            41424..42294
                     /locus_tag="VWX64_000175"
                     /pseudo
     CDS             41424..42294
                     /locus_tag="VWX64_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            42429..43388
                     /locus_tag="VWX64_000176"
     CDS             42429..43388
                     /locus_tag="VWX64_000176"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU9189740.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            43485..44324
                     /locus_tag="VWX64_000177"
     CDS             43485..44324
                     /locus_tag="VWX64_000177"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU9189741.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(44372..44542)
                     /locus_tag="VWX64_000178"
     CDS             complement(44372..44542)
                     /locus_tag="VWX64_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU9189742.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            44663..45547
                     /gene="miaA"
                     /locus_tag="VWX64_000179"
     CDS             44663..45547
                     /gene="miaA"
                     /locus_tag="VWX64_000179"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU9189743.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            45540..46778
                     /gene="hflX"
                     /locus_tag="VWX64_000180"
     CDS             45540..46778
                     /gene="hflX"
                     /locus_tag="VWX64_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU9189744.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            46771..47394
                     /locus_tag="VWX64_000181"
     CDS             46771..47394
                     /locus_tag="VWX64_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU9189745.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            47409..48338
                     /locus_tag="VWX64_000182"
     CDS             47409..48338
                     /locus_tag="VWX64_000182"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU9189746.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            48359..49114
                     /locus_tag="VWX64_000183"
     CDS             48359..49114
                     /locus_tag="VWX64_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU9189747.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(49168..50076)
                     /locus_tag="VWX64_000184"
     CDS             complement(49168..50076)
                     /locus_tag="VWX64_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9189748.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            50140..50409
                     /locus_tag="VWX64_000185"
     CDS             50140..50409
                     /locus_tag="VWX64_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU9189749.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            50409..50789
                     /locus_tag="VWX64_000186"
     CDS             50409..50789
                     /locus_tag="VWX64_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9189750.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNKEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            50878..51105
                     /locus_tag="VWX64_000187"
     CDS             50878..51105
                     /locus_tag="VWX64_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189751.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(51145..51870)
                     /locus_tag="VWX64_000188"
     CDS             complement(51145..51870)
                     /locus_tag="VWX64_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEU9189752.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            52032..53873
                     /gene="typA"
                     /locus_tag="VWX64_000189"
     CDS             52032..53873
                     /gene="typA"
                     /locus_tag="VWX64_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU9189753.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            53893..54147
                     /locus_tag="VWX64_000190"
     CDS             53893..54147
                     /locus_tag="VWX64_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU9189754.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            54512..54811
                     /locus_tag="VWX64_000191"
     CDS             54512..54811
                     /locus_tag="VWX64_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU9189755.1"
                     /translation="MKTKKHRLLALVLISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWDGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            54882..56903
                     /locus_tag="VWX64_000192"
     CDS             54882..56903
                     /locus_tag="VWX64_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9189756.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMALTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLIDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            56905..57546
                     /locus_tag="VWX64_000193"
     CDS             56905..57546
                     /locus_tag="VWX64_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189757.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            57650..58990
                     /locus_tag="VWX64_000194"
     CDS             57650..58990
                     /locus_tag="VWX64_000194"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU9189758.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNV
                     ENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQ
                     KALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKAGVAY
                     VEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE"
     gene            58992..60050
                     /locus_tag="VWX64_000195"
     CDS             58992..60050
                     /locus_tag="VWX64_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU9189759.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            60060..61259
                     /gene="divIB"
                     /locus_tag="VWX64_000196"
     CDS             60060..61259
                     /gene="divIB"
                     /locus_tag="VWX64_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU9189760.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRIEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     NQRSSRR"
     gene            61492..62193
                     /gene="pyrF"
                     /locus_tag="VWX64_000197"
     CDS             61492..62193
                     /gene="pyrF"
                     /locus_tag="VWX64_000197"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU9189761.1"
                     /translation="MREHRPIIALDFPNFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            62227..62859
                     /locus_tag="VWX64_000198"
     CDS             62227..62859
                     /locus_tag="VWX64_000198"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU9189762.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            63039..63442
                     /locus_tag="VWX64_000199"
                     /pseudo
     CDS             63039..63442
                     /locus_tag="VWX64_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            63538..64302
                     /locus_tag="VWX64_000200"
     CDS             63538..64302
                     /locus_tag="VWX64_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189763.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            64302..65054
                     /locus_tag="VWX64_000201"
     CDS             64302..65054
                     /locus_tag="VWX64_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189764.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            65064..65762
                     /locus_tag="VWX64_000202"
     CDS             65064..65762
                     /locus_tag="VWX64_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189765.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAIVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANEQMNFSCVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            65759..66406
                     /locus_tag="VWX64_000203"
     CDS             65759..66406
                     /locus_tag="VWX64_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189766.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(66493..67359)
                     /locus_tag="VWX64_000204"
     CDS             complement(66493..67359)
                     /locus_tag="VWX64_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9189767.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGPSSGKTTAKARTID
                     ENKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(67371..68128)
                     /locus_tag="VWX64_000205"
                     /pseudo
     CDS             complement(67371..68128)
                     /locus_tag="VWX64_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(68129..68806)
                     /locus_tag="VWX64_000206"
     CDS             complement(68129..68806)
                     /locus_tag="VWX64_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9189768.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(68766..69446)
                     /locus_tag="VWX64_000207"
     CDS             complement(68766..69446)
                     /locus_tag="VWX64_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9189769.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIHLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFG
                     NPSTLSGK"
     gene            69661..69807
                     /locus_tag="VWX64_000208"
     CDS             69661..69807
                     /locus_tag="VWX64_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU9189770.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            69934..71424
                     /gene="lysS"
                     /locus_tag="VWX64_000209"
     CDS             69934..71424
                     /gene="lysS"
                     /locus_tag="VWX64_000209"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU9189771.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            72049..73185
                     /gene="lctO"
                     /locus_tag="VWX64_000210"
     CDS             72049..73185
                     /gene="lctO"
                     /locus_tag="VWX64_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU9189772.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      73439..73527
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            73742..74410
                     /locus_tag="VWX64_000211"
     CDS             73742..74410
                     /locus_tag="VWX64_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU9189773.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDFALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(74515..74601)
                     /locus_tag="VWX64_000212"
                     /pseudo
     CDS             complement(74515..74601)
                     /locus_tag="VWX64_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            74692..75474
                     /gene="thiM"
                     /locus_tag="VWX64_000213"
     CDS             74692..75474
                     /gene="thiM"
                     /locus_tag="VWX64_000213"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9189774.1"
                     /translation="MTSLKLLKEKVPLVICITNDVVKNFTANGLVALSVSPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            75476..76105
                     /locus_tag="VWX64_000214"
     CDS             75476..76105
                     /locus_tag="VWX64_000214"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9189775.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      76314..76402
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            76664..77224
                     /locus_tag="VWX64_000215"
     CDS             76664..77224
                     /locus_tag="VWX64_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9189776.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSAMIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLSFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            77225..78610
                     /locus_tag="VWX64_000216"
     CDS             77225..78610
                     /locus_tag="VWX64_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189777.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHVQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIARKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTSIVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            78612..79262
                     /locus_tag="VWX64_000217"
     CDS             78612..79262
                     /locus_tag="VWX64_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU9189778.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQFKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            79273..79965
                     /gene="tenA"
                     /locus_tag="VWX64_000218"
     CDS             79273..79965
                     /gene="tenA"
                     /locus_tag="VWX64_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU9189779.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            79970..80494
                     /gene="thiW"
                     /locus_tag="VWX64_000219"
     CDS             79970..80494
                     /gene="thiW"
                     /locus_tag="VWX64_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU9189780.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            80494..81297
                     /locus_tag="VWX64_000220"
     CDS             80494..81297
                     /locus_tag="VWX64_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9189781.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            81290..81922
                     /locus_tag="VWX64_000221"
     CDS             81290..81922
                     /locus_tag="VWX64_000221"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9189782.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(82131..82922)
                     /gene="thiD"
                     /locus_tag="VWX64_000222"
     CDS             complement(82131..82922)
                     /gene="thiD"
                     /locus_tag="VWX64_000222"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9189783.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(83006..83104)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            83288..83683
                     /locus_tag="VWX64_000223"
     CDS             83288..83683
                     /locus_tag="VWX64_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU9189784.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            83694..84065
                     /locus_tag="VWX64_000224"
     CDS             83694..84065
                     /locus_tag="VWX64_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU9189785.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            84075..86318
                     /locus_tag="VWX64_000225"
     CDS             84075..86318
                     /locus_tag="VWX64_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9189786.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEAIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            86525..88300
                     /gene="spxB"
                     /locus_tag="VWX64_000226"
     CDS             86525..88300
                     /gene="spxB"
                     /locus_tag="VWX64_000226"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU9189787.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            88411..88758
                     /locus_tag="VWX64_000227"
     CDS             88411..88758
                     /locus_tag="VWX64_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9189788.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(88875..89247)
                     /locus_tag="VWX64_000228"
                     /pseudo
     CDS             complement(88875..89247)
                     /locus_tag="VWX64_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        27484 a        16009 c        19482 g        26272 t
ORIGIN      
        1 tacaaacaga atatgaaagc tttttatatc actattgaaa aatttatacg agatgatgaa
       61 agccttaagt gttattttac aaaggttatt tcaagtcgtt ccaaggtaac aagtctagat
      121 cagattgaag ctgataaaac gatacaaaga aaatattcaa gtgagctaaa aaaatttatt
      181 ggattttata atgagattat ttgtgaggaa aatagtttcc tacatgtacg aaagaggtgg
      241 tcgagttggt ttaggtagtc ggtgcgtgag ttgataattc tcagggtatg gacttctttt
      301 tcatgaatga ggtaaaagag caggtattgt ttagagacaa tcattctgag catattttct
      361 ggatagaggg agtatccgat tttatgatca aagttaatac cgccctctgg tgagaagatg
      421 agtaggttgg taatttaaac tattaaacag aatttttgat taaaagtatt atttcatgag
      481 agaaatccta atttcacaat ccataggcaa acgcttgcat tctgtttttt attggactat
      541 aataggttgg tataaagcct tctgtagtaa taaaatgtag aaggtgtaga aagtaaggat
      601 ttagaatatt tgtagttaaa aacacaatgt tgctattcct tatgataggg agatagatat
      661 ggcaatgata gaagtggaac atcttcagaa acattttgtg aagattgtta aggaaccggg
      721 cttgaagggg gctttgcgct cctttattca tcctgaaaag cagacctttg aagcggtcaa
      781 ggatttgacc tttgaggttc caaaagggca gattttagga tttatcgggg caaatggtgc
      841 tgggaagtcg acaaccatta aaatgctgac aggaattttg aaaccaacat ctggtttttg
      901 tcggattaac ggcaagattc cccaggacaa tcggcaagat tatgtcaaag atattggcgt
      961 agtctttgga caacgcaccc agctatggtg ggatttggct ctgcaagaga cctacactgt
     1021 cttaaaagag atttatgatg tgccagactc gctctttcat aagcgtatgg actttttgaa
     1081 tgaagtcttg gatttgaagg actttatcaa ggatcccgtg cggactcttt cactgggaca
     1141 acggatgcgg gcggatattg cggcctcctt gctccacaat cccaaggttc tttttttaga
     1201 tgagccgacc attggtttgg acgtttcggt taaggataat attcgtcggg caattactca
     1261 gatcaatcaa gaggaagaaa ctaccattct tttgaccact cacgatttga gtgatattga
     1321 gcaactttgt gatcggattt tcatgattga caaggggcaa gagatttttg atggaacagt
     1381 gagccaactc aaggagacct ttggtaagat gaagactctc tcttttgaac tgctaccagg
     1441 tcaaagtcat ctcgtctctc actatgaagg tctgtctgat atgaccattg atagacaagg
     1501 aaacagcctc aacattgaat ttgatagttc tcgctaccag tcagctgaca ttatcaagca
     1561 aaccctgtct gattttgaaa tccgcgattt gaagatggtg gatacggata ttgaggatat
     1621 tatccgtcgc ttctaccgaa aggagctcta ggatgatcaa attgtggaga cgttataaac
     1681 cctttatcaa tgcaggggtt caggagttga ttacttaccg agtcaacttt attctctatc
     1741 ggattggcga tgtcatgggg gcttttgtgg ccttttatct ctggaaggct gtctttgatt
     1801 cttcgcaaga gtctttgatt cagggcttca gtatggcgga tatcaccctc tacatcatca
     1861 tgagttttgt gaccaatctt ctgactagat ccgattcgtc ctttatgatt ggggaggagg
     1921 tcaaggatgg ctccattatc atgcgtttgt tgcgaccagt gcattttgcg gcctcctatc
     1981 ttttcaccga gcttggttcc aagtggttga tttttatcag cgttggcctt ccatttttaa
     2041 gtgtcattgt cttgatgaaa atcatatcgg gtcaaggtat tgtagaggtg ctaggattaa
     2101 ctgtcattta tctttttagc ttaacgctcg cctatctgat taactttttc tttaatattt
     2161 gctttggatt ttcagccttt gtgtttaaaa atctttgggg ttccaaccta cttaagactt
     2221 ccatagtggc ttttatgtcg gggagtttga ttcccttggc attctttcca aaggttgttt
     2281 cagatattct ctcctttttg cctttttcat ccttgattta tactccagtt atgatcattg
     2341 ttggaaaata cgatgccagt cagattcttc aggcactcct tttgcagttc ttctggctct
     2401 tagtgatggt gggattgtct cagttgattt ggaaacgggt ccagtccttt atcaccattc
     2461 aaggaggtta gtatgaaaaa atatcaacga atgcatctga tttttatcag acaatacatc
     2521 aaacaaatca tggaatataa ggtggatttt gtggttggtg tcttgggagt ctttctggct
     2581 caaggcttga atctcttgtt tctcaatgtc atctttcaac atattccatt cctagaaggc
     2641 tggacctttc aagagatagc tttcatttat ggattttcct tgattcccaa gggaatggac
     2701 catctctttt ttgacaatct ctgggcacta gggcaacgcc tagtccgaaa aggggagttt
     2761 gacaagtatc tgactcgtcc catcaatcct ctctttcaca tcctagttga aacctttcag
     2821 attgatgcct tgggtgaact cttagtcggt ggtattttat tgggaacaac agtgaccagc
     2881 attgtttgga ctcttccaaa atttctgctt ttcctagttt gtattccttt tgcgaccttg
     2941 atttatactt ctcttaaaat cgcaacagcc agtatcgcct tttggactaa gcagtcaggc
     3001 gccatgattt acatcttcta tatgttcaat gactttgcta agtatccgat ttctatttac
     3061 aattctcttc ttcgttggtt gattagcttt atcgtgcctt tcgcctttac agcctactat
     3121 ccagctagct atttcttaca ggaaaaggat gtgttcttta acgtaggagg tttgatgttg
     3181 atttctctga ttttctttgt tatttccctt aaactttggg ataagggctt agattcctac
     3241 gaaagtgcgg gttcgtaaaa gctaaagtaa gactaaaatc aagaaaggaa cttatgatgt
     3301 ttgtaattga agaagtcaag gatgaaaatc aaaaaaaggc agttgtcgct gaggttttga
     3361 aggatttgcc agaatggttt ggaatcccag aaagcacaca agcctatata gaaggaacca
     3421 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaagcttat
     3481 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3541 tagaaaaatt gggagccaat tgtttgctac tttagagagt gaagctcgta aaaaagttgg
     3601 ttatctgcag gtcaaaacag tggcagaagg ttctaataaa gattatgatc gaacaaatga
     3661 cttttatcga ggttttggct ttaaaaagtt agagattttt cttcaactat ggaatccgca
     3721 aaatccttgt cagattttga ttaaaaagct tgaataatat tatttgacat ctattctcag
     3781 agtgctatac tgtaagtgta atcgccgatt tagctcagtt ggtagagcaa ggcactcgta
     3841 aagcctaggt tataggtaga taaacgactg aggagttgaa aaaatagata ggtagaagat
     3901 aaccgttaag ccttattctt agcggttatt tatattgttt aatagcgctg atatttcatc
     3961 aattatgcct gttttcgtgt ttctggtagt tgttcaagtt tattgctact atttttgatg
     4021 gtatgaatgt gcttataatg tatcccggtt aacgaaagtt ttggacttat actcttagaa
     4081 aatctcttca aaccacgtca acgtcgcctt gccgtgcgta tggttactga cttcgtcagt
     4141 tctatccaca acctcaaaac agtgttttga gcaacctgcg gctagtttcc tagtttgctc
     4201 tttgattttc attgagtact aatcttattt tttaacgtgt gctaaaaaat aaattaatgc
     4261 atgttaattt ttcttgaatt aaattttttt aaatgatata ctgtttttat ggagagataa
     4321 caattatata taaatgtact actctatttc ctagataata cttagtaaaa ctttttataa
     4381 caaaggctag caaagttaaa gtttattatc tattggagtt taaataaata tgtaaggaat
     4441 taaaatgaaa aaaagtacag tattgtcatt aaccacagct gcagttattt tagcagccta
     4501 tgcccctaat gaggtagtct tagcagacac atctaactct gaagatgctt taagcatctc
     4561 tgataaagaa aaagtagcag aaaataaaga gaaacatgaa aatatccata gtgctatgga
     4621 aacttcacag gattttaaag agaagaaaac agcagtcatt aaggaaaaag aagttgttag
     4681 taaaaatcct gtgatagaca ataacactag caatgaagaa gcaaaaatca aagaagaaaa
     4741 ttccaatcaa tcccaaggag attatacgga ctcatttgtg aataaaaaca cagaaaatcc
     4801 caaaaaagaa gataaagttg tctatattgc tgaatttaaa gataaagaat ctggagaaaa
     4861 agcaatcaag caactatcca gtcttaagaa tacaaaagtt ttatatactt atgatagaat
     4921 ttttaacggt agtgccatag aaacaactcc agataacttg gacaaaatta aacaaataga
     4981 aggtatttca tcggttgaaa gggcacaaaa agtccaaccc atgatgaatc atgccagaaa
     5041 ggaaattgga gttgaggaag ctattgatta cctaaagtct atcaatgctc cgtttgggaa
     5101 aaattttgat ggtagaggta tggtcatttc aaatatcgat actggaacag attatagaca
     5161 taaggctatg agaatcgatg atgatgccaa agcctcaatg agatttaaaa aagaagactt
     5221 aaaaggaact gataaaaatt attggttgag tgataaaatc cctcatgcgt tcaattatta
     5281 taatggtggc aaaatcactg tagaaaaata tgatgatgga agagattatt ttgacccaca
     5341 tgggatgcat attgcaggga ttcttgctgg aaatgatact gaacaagata tcaaaaactt
     5401 taacggcata gatggaattg cacctaatgc acaaattttc tcttacaaaa tgtattctga
     5461 cgcaggatct gggtttgcgg gtgatgaaac aatgtttcat gctattgaag attctatcaa
     5521 acacaacgtt gatgttgttt cggtatcatc tggttttaca ggaacaggtc ttgtaggtga
     5581 gaaatattgg caagctattc gggcattaag aaaagcaggc attccaatgg ttgtcgctac
     5641 gggtaactat gcgacttctg cttcaagttc ttcatgggat ttagtagcaa ataatcatct
     5701 gaaaatgacc gacactggaa atgtaacacg aactgcagca catgaagatg cgatagcggt
     5761 cgcttctgct aaaaatcaaa cagttgagtt tgataaggtt aacattggag gacaaagttt
     5821 taaatacaga aatatagggg cctttttcga taagaataaa atcacaacaa atgaagatgg
     5881 aacaaaagct cctagtaaat taaaatttgt atatataggc aaggggcaag accaagattt
     5941 gataggtttg gatcttaggg gcaaaattgc agtaatggat agaatttata caaaggattt
     6001 aaaaaatgct tttaaaaaag ctatggataa gggtgcacgc gccattatgg ttgtaaatac
     6061 tgtaaattac tacaatagag ataattggac agagcttcca gctatgggat atgaagcgga
     6121 tgaaggtact aaaagtcaag tgttttcaat ttcaggagat gatggtgtaa agctatggaa
     6181 catgattaat cctgataaaa aaactgaagt caaaagaaat aataaagaag attttaaaga
     6241 taaattggag caatactatc caattgatat ggaaagtttt aattccaaca aaccgaatgt
     6301 aggtgacgaa aaagagattg actttaagtt tgcacctgac acagacaaag aactctataa
     6361 agaagatatc atcgttccag caggatccac atcttggggg ccaagaatag atttactttt
     6421 aaaacccgat gtttcagcac ctggtaaaaa tattaaatcc acgcttaatg ttattaatgg
     6481 caaatcaact tatggctata tgtccggaac tagtatggcg actccaatcg tagcagcttc
     6541 tactgttttg attcgaccaa aattgaagga aatgcttgaa aaacccgtat taaaaaatct
     6601 taaaggtgat gataaaatag accttacaag tcttacaaaa atagccctac aaaatactgc
     6661 aagacctatg atggatgcaa cttcttggaa agaaaaaagt caatactttg catcacctag
     6721 acagcagggg gcggggctaa ttaatgtggc caacgctttg agaaatgaag ttgtagcgac
     6781 tttcaaaaac acggattcta aaggtttggt aaattcatat ggttccattt ctcttaaaga
     6841 aataaaaggt gataaaaaat actttacaat taagcttcac aatacatcca acaggccttt
     6901 aacctttaaa gtttcagcat cagcggtaac tacagattct ctaactgaca gactaaaact
     6961 ggatgaaaca tataaagatg aaaaatctcc agatggtaag caaattgttc cagaaattca
     7021 tccagaaaaa gtcaaagggg caaatattac atttgagcat gacactttca ctataggggc
     7081 aaattctagc tttgatttaa atgcggttat aaatgttggg gaggctaaaa ataaaaataa
     7141 atttgtagaa tcatttattc attttgagtc agtagaagaa atggaagcat taagctccaa
     7201 tggcaagaaa accgacttcc aaccatcttt atcaatgccc ctgatgggat ttgctgggaa
     7261 ttggaaccac gaaccaatcc ttgataaatg ggcttgggaa gaaggatcaa aatcaaaaac
     7321 aatggaaggt tatgatgatg acggtaaacc aaaaattcca ggaaccttaa ataaggggat
     7381 tggtggagaa catggtatag ataaatttaa tccagcagga gttatccaaa atagaaaaga
     7441 taaaaataga acatctctag atcaagatcc agacttattt gcctttaaca accaaggtgt
     7501 tcatgcagga tccactagtg gttctaagat tgctaacatt tatcctttag attcaaatgg
     7561 aaatcctcaa gatgctcaac tagaaagagg actaactcca tctccacttg ttctaagaag
     7621 tgcagaagaa ggactaattt caattgtaaa caccaacaaa gaaggagaaa accaaaaaga
     7681 ccttaaagtt gtatcaagag agcacttcat aagaggaatt ctaaattcta agggaaatga
     7741 cgctaagggt atcaaatcat ccaaactaaa agtttggggt gacttgaaat gggatggact
     7801 catctataac ccaagaggta gagaagaaaa tgccccagaa agtaaggata accaagatcc
     7861 agctactaag atacgaggac aatttgaacc gattgcggaa ggtcaatatt tctataaatt
     7921 taaatataga ttaactaaag attacccatg gcaggtttcc tatattcctg taaaaattga
     7981 taacacagcc cctaagattg tttcggttga tttttcaaat cctgaaaaaa ttaagctaat
     8041 cacaaaggat acttatcaca aggtaaaaga tcaatacaag aatgaaactt tatttgctag
     8101 agatcaaaaa gaacatcctg aaaaatttga tgagattgca aatgaggtgt ggtatgcagg
     8161 agctgctctt gttaatgaag atggagaggt tgagaaaaat cttgaagtaa cttatgcagg
     8221 tgagggtcaa ggaagaaata ggaagcttga taaagatggg aatactatct atgaaattag
     8281 cggagcagga gatctaagag gaaaaatcat cgaagtaatc gccctagatg gagcaagcaa
     8341 ctttaccaaa atccatagga ttaaatttgc taatcaagct gatgaaaaag ggatgatttc
     8401 ctattatcta gtagatcctg atcaggattc atctaaatac caaaagcttg gcgaaattcc
     8461 tgaatctaaa tttaagaatt taaaaaatgt taaagatgat agcctaaaca aagagacagc
     8521 tgaggtggaa aataaccttt tagtagataa tcagtctatc gaaggaaaat ctctctttaa
     8581 tattcataaa actatttcaa caattagaga ctttgaaaat aaagacctaa agaaactcat
     8641 taaaaagaaa tataagcaag aagacgactt tgtaaatggt ggaacaagaa cagtagagcg
     8701 tgattataaa tacgatgata aaggaaatat aatagcctac gatgatggga ctgatctaga
     8761 atatgaaact gagaaacttg acgaaatcaa atcaaaaatt tatggtgttc taagtccgtc
     8821 taaagatgga cactttgaaa ttcttggaaa gataagtaat gtttctaaaa atgccaaggt
     8881 atattatggg aataactata aatctataga aatcaaagcg accaagtatg atttccactc
     8941 aaaaacgatg acatttgatc tatacgctaa tattaatgat attgtggatg gattagcttt
     9001 tgcaggagat atgagattat ttgttaaaga taatgatcag aaaaaagctg aaattaaaat
     9061 tagaatgcct gaaaaaatta aggaaactaa atcagaatat ccctatgtat caagttatgg
     9121 gaatgtcata gaattagggg aaggagatct ttcaaaaaac aaaccagaca atttaactaa
     9181 aatggaatct ggtaaaatct attctgattc agaaaaacaa caatatctgt taaaggataa
     9241 tatcattcta agaaaaggct atgcactaaa agtgactacc tataatcctg gaaaaacgga
     9301 tatgttagaa ggaaatggag tctatagcaa ggaagatata gcaaaaatac aaaaggccaa
     9361 tcctaatcta agagcccttt cagaaacaac aatttatgct gatagtagaa atgttgaaga
     9421 tggaagaagt acccaatctg tattaatgtc ggctttggac ggctttaaca ttataaggta
     9481 tcaagtgttt acatttaaaa tgaacgataa aggggaagct atcgataaag acggaaatct
     9541 tgtgacagat tcttctaaac ttgtattatt tggtaaggat gataaagaat acactggaga
     9601 ggataagttc aatgtagaag ctataaaaga agatggctcc atgttattta ttgataccaa
     9661 accagtaaac ctttcaatgg ataagaacta ctttaatcca tctaaatcta ataaaattta
     9721 tgtacgaaat ccagaatttt atttaagagg taagatttct gataagggtg gttttaactg
     9781 ggaattgaga gttaatgaat cggttgtaga taattattta atctacggag atttacacat
     9841 tgataacact agagatttta atattaagct gaatgttaaa gacggtgaca tcatggactg
     9901 gggaatgaaa gactataaag caaacggatt tccagataag gtaacagata tggatggaaa
     9961 tgtttatctt caaactggct atagtgattt gaatgctaaa gcagttggag tccactatca
    10021 gtttttatat gataatgtta aacccgaagt aaacattgat cctaagggaa atactagtat
    10081 cgaatatgct gatggaaaat ctgtagtctt taacatcaat gataaaagaa ataatggatt
    10141 cgatggtgag attcaagaac aacatattta tgtaaatgga aaagaatata catcatttga
    10201 tgatattaaa caaataacag acaagacact aaacattaag attgttgtaa aagattttgc
    10261 aagaaataca accgtaaaag aattcatttt aaataaagat acgggagagg taagtgaatt
    10321 aaaacctcat agggtaactg tgaccattca aaatggaaaa gaaatgagtt caacgatagt
    10381 gtcggaagaa gattttattt tacctattta taagggtgaa ttagaaaaag gataccaatt
    10441 tgatggttgg aaaatttctg gtttcgaagg taaaaaagac gctggctatg ttattaatct
    10501 atcaaaagat acctttataa aacctgtatt caagaaaata gaggagaaaa aggaggaaga
    10561 aaataaacct acttttgatg tatcgaaaaa gaaagataac ccacaagtaa accatagtca
    10621 attaaatgaa agtcacagaa aagaggattt acaaagagaa gatcattcac aaaaatctga
    10681 ttcaactaag gatgttacag ctacagttct tgataaaaac aatatcagta gtaaatcaac
    10741 tactaacaat cctaataagt tgccaaaaac tggaacagca agcggagccc agacactatt
    10801 agctgccgga ataatgttta tagtaggaat ttttcttgga ttgaagaaaa aaaatcaaga
    10861 ttaagacaaa agctatagaa aaaaatggtt tatgtactga gattagatag tgaggtgatg
    10921 acatagtttt gtgaaaacag ccatttataa ctcaattatt tagcttactt cactattgat
    10981 actatttgga gttattaatg gacttagttt agataactaa tgaattgatt gaaagggtta
    11041 gtattgacaa tattggtcat attgattaga aaatagagtc tatcaaaatt taaaggctaa
    11101 tagaggtgat gagacaattt caaggaatta agtagcgttt ggttgcttaa ttccttttta
    11161 tttggaagga agtttttcgt aaccgcccaa taacgaagtc tattgggcgg ttacgatatg
    11221 atcactgact tcgtcagttc tatctacaac ctaaaaacag tgttttgaac aacctgcggc
    11281 tagcttccta gtttgctctt tgattttcat tgaatattag aacagcaaaa atgcttggag
    11341 tatttgtttg tgtgtttgtt tttatataac aaactataaa caaaacaaaa atataaaaaa
    11401 agagacaaaa aagaacaaaa agtaattgac aacggtttca tatagtgtta tacttatggc
    11461 ataaagttaa tggaaagaag ggaaaacctt atggtattag attatttctt tgacaaaaac
    11521 cttgtgtttt gcttagaagc ggataatcaa gaacaactct ttgatcaggt tgcaacttta
    11581 ttggaagaac gagaaattgt cactccaact tatcgtgaag ccttgatcac gcgtgaaaag
    11641 tcatttccaa ctggtttaga tatggaattt ctaggaaagg acttgccaaa tgtagcgatt
    11701 cctcatacag atattgttca taatctagct gagaaagtgg tggttgttcg attagaaaaa
    11761 ccagtaactt ttcacaatat gatagctcct gataaggaag tagaagtatc cttgctcttc
    11821 tttatcatca ataactcaag ttcaagtcaa acaaatattc tggctcagtt gatggacttt
    11881 ttcacaggaa atggacatct tgaagaccta tcaaaaattt ccgaaccaga aaaactttat
    11941 gcttacattg ctgaagcaac cgcttaatct tgtctattaa aaaataaaat cggaggaaat
    12001 ctaaatgatt aaaattcttg ctgcctgcgg tgcaggtgtt aactcaagtc accaaattaa
    12061 aagtgctcta gaagaagaac tttcaaaccg tggttatgat gttcactgtg atgcagtcat
    12121 ggtgaaagat gtaaacgaag accttatgaa aggttacgat atctttacac caatcgctgc
    12181 aacagacctt ggttttgaac caggtatccc agttatcgaa gctggaccaa tcttattccg
    12241 tatcccagca atgagcgctc cagtatttga caatattgaa gcagctatta aagaacacgg
    12301 attaagctaa ttctaatttg ttaacattca tataacataa aaaagggagg aactgttatg
    12361 gatgcaatct ttgacctaat cggaaaggtt ttcaatccca tcttagaaat gggtggacct
    12421 gtcatcatgt taatcatttt gacagtattg gctttacttt ttggagtgaa attctccaaa
    12481 gcgcttgaag gtggtatcaa acttgccatc gctcttacag gtatcggtgc tatcatcggt
    12541 atgctaaatg gtgctttctc agcatcactt gcaaaattcg ttgaaaacac tggtatacaa
    12601 ttgagtatta ccgacgttgg ttgggcacca cttgcaacaa tcacttgggg ttctgcttgg
    12661 acactttact tcttgctcat catgttgatt gtcaacgtag tgatgcttgc tatgaagaaa
    12721 accgatacac ttgatgtcga tatctttgat atctggcact tgtctatcac aggtctcttg
    12781 attaaatggt atgctgataa caatggtgtg agtcaagggg tttcactctt gattgctaca
    12841 gcagctatcg ttcttgtcgg tgtgttgaaa attatcaact ctgacttgat gaaacctaca
    12901 tttgatgacc ttcttaacgc cccaagttca tcaccaatga catcaactca catgaactac
    12961 atgatgaacc cagttatcat ggttttggat aagatttttg aaaaattctt cccaggcctt
    13021 gataaatatg actttgatgc tgctaaattg aacaagaaaa tcggtttctg gggatctaaa
    13081 ttcttcatcg gtttcatcct tggtatcgtt atcggtatta tgggaactcc acatccaatt
    13141 gcaggtgttg cagatgcaga taaatggcgt cttgttatca aaggatggtt gtctcttggt
    13201 ttgactgccg gtgtatcttt ggaactcttc tcacttatcg gttcatggtt catcgcagcc
    13261 gtagaaccac tatcacaagg tattacaaac gttgctacta aacgtcttca aggacgtaaa
    13321 ttcaatatcg gtcttgactg gccattcatc gctggtcgtg ctgaaatctg ggcttgtgcc
    13381 aacgtacttg caccaatcat gttgattgaa gcagtgcttc tttcaaaagt tggaaatggt
    13441 atcttgccac ttgcaggtat catcgctatg ggtgttactc cagctctctt ggttgtaact
    13501 cgtggtaaat tgctccgtat gattatcttc ggaacactct tgttgccact cttccttctt
    13561 tcaggtaccc ttattgcacc atttgcaaca gaacttgcta aaggtgtagg tgccttccca
    13621 gaaggtgtga gccaaactca attgattact cactctactc ttgaaggacc aatcgaaaaa
    13681 cttcttggtt ggacaattgg taacactaca actggtgata tcaaagcaat ccttggtgca
    13741 gtagccttcc ttgtattcta tatcggtatc tttgcttggt acagaaaaca aatgatcaaa
    13801 cgtaacgaag agtacgcagc aaaagcaaaa taatgcgctc ctataaaata taaactcaat
    13861 gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc tcaaaacaca gttttgaggt
    13921 tgtagataag actgacgaag tcagctcaaa acatggtttt gaggttgtag atgaaactga
    13981 cgaagtcagc tcaaaacatg gttttgaggt tgtagatgaa actgacgaag tcagtaatca
    14041 tatctacggc aaggcgacac tgacgaagtt tgaattggat tttcgcagag tgtaaattgt
    14101 tgaaactagg ttgtcatacc atgtatacca cttgggcttt ggtagtagct aactgcacta
    14161 aatataatat aaggagggtt ttatggggaa aggccattgg aatcggaaaa gagtttatag
    14221 cattcgtaag tttgctgtgg gagcttgctc agtaatgatt gggacttgtg cagttctatt
    14281 aggaggaaat atagctggag aatctgtagt ttatgcggat gaaacactta ttactcatac
    14341 tgctgagaaa cctaaagagg aaaaaatgat agtagaagaa aaggctgata aagctttgga
    14401 aactaaaaat gtagttgaaa ggacagaaca aagtgaacct agttcaactg aggctattgc
    14461 atctgagaag aaagaagatg aagccgtaac tccaaaagag gaaaaagtgt ctgctaaacc
    14521 ggaagaaaaa gctccaagga tagaatcaca agcttcaagt caagaaaaac cgctcaagga
    14581 agatactaaa gctgtaacaa atgaagaagt gaatcaaatg attgaagaca ggaaagtgga
    14641 ttttaatcaa aattggtact ttaaactcaa tgcaaattct aaggaagcca ttaaacctga
    14701 tgcagacgta tctacgtgga aaaaattaga tttaccgtat gactggagta tctttaacga
    14761 tttcgatcat gaatctcctg cacaaaatga aggtggacag ctcaacggtg gggaagcttg
    14821 gtatcgcaag actttcaaac tagatgaaaa agacctcaag aaaaatgttc gccttacttt
    14881 tgatggcgtc tacatggatt ctcaagttta tgtcaatggt cagttagtgg ggcattatcc
    14941 aaatggttat aaccagttct catacgatat caccaaatac cttcacaaag atggtcgtga
    15001 gaatgtgatt gctgtccatg cagtcaacaa acagccaagt agccgttggt attcaggaag
    15061 tggtatctat cgtgatgtga ctttacaagt gacagataag gtgcatgttg agaaaaatgg
    15121 gacaactatt ttaacaccaa aacttgaaga acaacaacat ggcaaggttg aaactcatgt
    15181 gaccagcaaa atcgtcaata cggacgacaa agaccatgaa cttgtagccg aatatcaaat
    15241 cgttgaacga ggtggtcatg ctgtaacagg cttagttcgt acagcgagtc gtaccttaaa
    15301 agcacatgaa tcaacaagcc tagatgcgat tttagaagtt gaaagaccaa aactctggac
    15361 cgttttaaat gacaaacctg ccttgtacga attgattacg cgtgtttacc gtgacggtca
    15421 attggttgat gctaagaagg atttgtttgg ttaccgttac tatcactgga ctccaaatga
    15481 aggtttctct ttgaatggtg aacgtattaa attccatgga gtatccttgc accacgacca
    15541 tggggcgctt ggagcagaag aaaactataa agcagaatat cgccgtctca aacaaatgaa
    15601 ggagatggga gttaactcca tccgtacaac ccacaaccct gctagtgagc aaaccttgca
    15661 aatcgcagca gaactaggtt tactcgttca ggaagaggct tttgatactt ggtatggtgg
    15721 caagaaacct tatgactatg gacgtttttt tgaaaaagat gccactcacc cagaagctcg
    15781 aaaaggtgaa aaatggtctg attttgacct acgtaccatg gtcgaaagag gcaaaaacaa
    15841 ccctgctatc ttcatgtggt caattggtaa tgaaataggt gaagctaatg gtgatgccca
    15901 ctctttagca actgttaaac gtttggtcaa ggttatcaag gatgttgata agactcgcta
    15961 tgttaccatg ggagcagata aattccgttt cggtaatggt agcggagggc atgagaaaat
    16021 tgctgatgaa ctcgatgctg ttggatttaa ctattctgaa gataattaca aagcccttag
    16081 agctaagcat ccaaaatggt tgatttacgg ttcagaaaca tcatcagcaa cccgtacacg
    16141 aggaagttac tatcgccctg aacgtgaatt gaaacatagc aatggacctg agcgtaatta
    16201 tgaacagtca gattatggaa atgatcgtgt tggttggggg aaaacagcaa ccgcttcatg
    16261 gacttttgac cgtgacaacg ctggctatgc tggacagttt atctggacag gtacggacta
    16321 tattggtgaa cctacaccat ggcacaacca aaatcaaact cctgttaaga gctcttactt
    16381 tggtatcgta gatacagccg gcattccaaa acatgacttc tacctctacc aaagccaatg
    16441 ggtttctgtt aaaaagaaac cgatggtaca ccttcttcct cactggaact gggaaaacaa
    16501 agaattagca tccaaagtag ctgactcaga aggtaagatt ccagttcgtg cttattcgaa
    16561 tgcttctagt gtagaattgt tcttgaatgg aaaatctctt ggtcttaaga ctttcaataa
    16621 aaaacaaacc agcgatgggc ggacttacca agaaggtgca aatgctaatg aactttatct
    16681 tgaatggaaa gttgcctatc aaccgggtac cttggaagca attgctcgtg atgaatctgg
    16741 caaggaaatt gctcgagata agattacgac tgctggtaag ccagcggcag ttcgtcttat
    16801 taaggaagac catgcgattg cagcagatgg aaaagacttg acttacatct actatgaaat
    16861 tgttgacagc caggggaatg tggttccaac tgctaataat ctggttcgct tccaattgca
    16921 tggccaaggt caactggtcg gtgtagataa cggagaacaa gccagtcgtg aacgctataa
    16981 ggcgcaagca gatggttctt ggattcgtaa agcatttaat ggtaaaggtg ttgccattgt
    17041 caaatcaact gaacaagcag ggaaattcac ccttactgcc cactctgatc tcttgaaatc
    17101 gaaccaagtc actgtcttta ctggtaagaa agaaggacaa gagaagactg ttttggggac
    17161 agaagtgcca aaagtacaga ccattattgg agaggcacct gaaatgccta ccactgttcc
    17221 gtttgtatac agtgatggta gccgtgcaga acgtcctgta acctggtctt cagtagatgt
    17281 gagcaagcct ggtattgtaa cggtgaaagg tatggctgac ggacgagaag tagaagctcg
    17341 tgtagaagtg attgctctta aatcagagct accagttgtg aaacgtattg ctccaaatac
    17401 tgacttgaat tctgtagaca aatctgtttc ctatgttttg actgatggaa gtgttgaaga
    17461 gtatgaagtg gacaagtggg agattgccga agaagataaa gctaagttag caattccagg
    17521 ttctcgtatt caagcgaccg gttatttaga aggtcaacca attcatgcaa cccttgtggt
    17581 agaagaaggc aatcctgcgg cacctgcagt accaactgta acggttggtg gtgaagctgt
    17641 cacaggtctt actagtcaaa aaccaatgca ataccgcact cttgcttatg gagctaagtt
    17701 gccagaagtc acagcaagtg ctaaaaatgc agctgttaca gttcttcaag caagcgcagc
    17761 aaacggcatg cgtgcgagca tctttattca gcctaaagat ggtggccctc ttcaaaccta
    17821 tgcaattcaa ttccttgaag aagcgccaaa aattgctcac ttgagcttgc aagtggaaaa
    17881 agctgacagt ctcaaagaag accaaactgt caaattgtcg gttcgagctc actatcaaga
    17941 tggaacgcaa gctgtattac cagctgataa agtaaccttc tctacaagtg gtgaagggga
    18001 agtcgcaatt cgtaaaggaa tgcttgagtt gcataagcca ggagcagtca ctttgaacgc
    18061 tgaatatgag ggagctaaag gccaagttga actcactatc caagccaata ctgagaagaa
    18121 gattgcgcaa tccatccgtc ctgtaaatgt agtgacagat ttgcatcagg aaccaagtct
    18181 tccagcaaca gtaacagttg agtatgacaa aggttttcct aaaactcata aagtcacttg
    18241 gcaagctatt ccgaaagaaa aactagactc ctatcaaaca tttgaagtac taggtaaagt
    18301 tgaaggaatt gaccttgaag cgcgtgcaaa agtctctgta gaaggtatcg tttcagttga
    18361 agaagtcagt gtgacaactc caatcgcaga agcaccacaa ttaccagaaa gtgttcggat
    18421 atatgattca aatggtcacg tttcatcagc taaggttgca tgggatgcga ttcgtccaga
    18481 gcaatacgct aaggaaggtg tctttacagt taatggtcgc ttagaaggta ctcaattaac
    18541 aactaaactt catgttcgcg tatctgctca aactgagcaa ggtgcaaaca tttctgacca
    18601 atggaccggt tcagaattgc cacttgcctt tgcttcagat tcaaatccaa gcgacccagt
    18661 ttcaaatgtt aatgacaagc tcatttccta caataaccaa ccagccaatc gttggacaaa
    18721 ctggaatcgt agtaatccag aagcttcagt cggtgtccta ttcggagatt caggtatttt
    18781 gagcaaacgt tcagttgata acttaagcgt tggcttccat gaagaccatg gagttggtgc
    18841 accgaagtct tatgtgattg agtattatgt tggtaagact gtcccaacag ctcctaaaaa
    18901 ccctagtttt gttggtaatg aggaccatgt ctttaatgat tctgccaact ggaaaccagt
    18961 tactaatcta aaagcccctg ctcaactcaa ggctggagaa atgaaccact ttagctttga
    19021 taaagttgaa acctatgctg ttcgtattcg catggtgaga gcagacaaca aactaggaac
    19081 gtctatcaca gaggtacaaa tctttgcgaa acaagttgcg gcagccaagc aaggacaaac
    19141 aagaatccaa gttgacggta aagacttagc aaacttcaac cctgatctga cagactacta
    19201 ccttgagtct gtagatggaa aagttccggc agtcacagca agtgttagca acaatggtct
    19261 cgctaccgtc gttccaagcg ttcgtgaagg tgagccagtt cgtgtcatcg cgaaagctga
    19321 aaatggcgac atcttaggag aataccgtct gcacttcact aaggataaga acttactttc
    19381 tcataaacca gttgctgcgg ttaaacaagc tcgcttgcta caagtaggtc aagcacttga
    19441 attgccgact aaggttccag tttacttcac aggtaaagac ggctacgaaa caaaagattt
    19501 gtcagttgaa tgggaagaag ttccagcaga aaatctgaca aaagcaggtc aatttaccgt
    19561 tcgaggccat gtccttggta gtgatcttgt tgctgaggtc actgtacgag tgacagacaa
    19621 actaggcgaa gctctttcag ataaccctaa ctatgatgaa aacagtaacc aggcctttgc
    19681 ttcagcaacc aatgatattg acaaaaactc tcatgaccgc gttgactatc tcaatgacgg
    19741 agatcattca gaaaatcgtc gttggacaaa ctggtctcca acaccatctt ctaatccaga
    19801 agtatcagcg ggtgtgatct tccgtgaaaa tggtaagatt gtagaacgga ctgttgcgca
    19861 agccaaactt cacttctttg cagatagtgg tacggatgca ccaactaaac tcgttttaga
    19921 acgctatgtc ggtccagagt ttgaagtgcc aacctactat tcaaactacc aagcctacga
    19981 cgcagaccat ccattcaaca atccagaaaa ttgggaagct gtgccttatc gtgcggataa
    20041 agacatcgca gctggtgatg aaatcaacgt aacatttaaa gctgtcaaag ccaaagctat
    20101 gagatggcgt atggagcgta aagcagataa gagcggtgtt gcgatgattg agatgacctt
    20161 ccttgcacca agtgaattgc ctcaagaaag cacgcaatcg aagattcttg tagatggaaa
    20221 agaacttgct gatttcgctg aaaatcgtca agactatcaa attacctata aaggtcaacg
    20281 gccaaaagtc tcagttgaag aaaacaatca agtagcttca actgtggtag atagtggaga
    20341 agatagcctt ccagtacttg ttcgcctcgt ttcagaaagt ggaaaacaag ttaaggaata
    20401 ccgtatccag ttgactaagg aaaaaccagt ttctgagaag acagttgctg ctgtacaaga
    20461 agatcttcca aaactcgaat ttgttgaaaa agatttggcc tacaagacag ttgagaaaaa
    20521 agattcaaca ctgtatctag gtgaaactcg tgtagaacaa gaaggaaaaa ctggtaaaga
    20581 acgtatcttt acagcgatta atcctgatgg aagtaaggaa gaaaaactcc gtgaagtggt
    20641 agaagctccg acagaccgca tcgtcttggt tggaaccaaa ccagtagctc aagaagctaa
    20701 aaaaccacaa gtgtcagaaa aagcagatac aaaaccaatt gattcaagtg aagctagtca
    20761 aactaataaa gcccagttac caaatacagg tagtgcgtca agccaagcag cagtagcagc
    20821 aggtttagct cttctaggtt tgagtgcagg attagtagtt actaaaggta aaaaagaaga
    20881 ctagaaattt tgataccttc tttatcatta aagaccaaag aaaaactctt gtcctaaata
    20941 gaagataaag agtctggaac aaaatagttc tcaaccacaa aaaagctaga tatttccaat
    21001 tgcggaactc tagcttttta attttgagtc gttctcttat tgtatagtag attgaaacta
    21061 gagtagtaca cttctacttc taaaacattg ttagaaatcg atttgactgt ccttatcgat
    21121 ttgtcctgtt cttatttcat ttcactatgt tttaggaggt tattggccat aagtaccaat
    21181 cccatgtcaa ttctcacttg acgcttgcct ctcagattac atctcttgta acccaaacaa
    21241 gcctttatct gcccaaagac aggttccaca tcaatcttgc gttgagcgaa aatctgtcta
    21301 tcttggggag ataaaagcgc ctgacattct ttagctttca agttttgata gcgttcgttc
    21361 atatacagtc ccttttgagg ggctgattca ggttcatcag cgtagtaaac cttgatttcc
    21421 tgttgaaagt ctgtctgtgt tttctggtac ttgatatggt gaaaacgata gcaccagcca
    21481 tcaggatgta tgtagctatc ctccttgtca ttatagtgcc aattcgctaa gtttttagct
    21541 gactgtttat accctctctt ttgtttctta tcaaacatgg catatttaat cagaagggga
    21601 gtgatttctt cttgaaaata gacttgtatc tgttcttgaa gtttggcgga gaatttctct
    21661 gtcgttttct tccacacaaa actatacttg ttggcattgg cttcaatctt agttccgtca
    21721 ataaacaaac aatctaaggt cactaactct tccatttttc aatttttcga ccagagaaaa
    21781 tcccttgtga ataggcaaat agaagagtag atacaagcat tttaaggtga taagacgggc
    21841 gatcaaaggc atgatagaag gcgtggaaat gacaatcctc caaggtattc accacttttt
    21901 caatagtaaa aacgagatgg tcttgtggca agaaggaact gatttctagt ggtaaagttg
    21961 tttgatttgt gttatagtga atatgcatgg gatagccttt ctaaatggtt tattgtgcaa
    22021 ttctatttta ccaagactat cgcaaccatg caaaaaagca acggcaaatc cgttgctttt
    22081 tttggagata agagactatt gtcccagact cttttctttg tataaaattg tatagtgtta
    22141 ttgtctatac tattttgtag agaaagcaaa aatccctaga aaatgcttag ggattcgact
    22201 atttcattaa gaacaattca acaatcattt ctacatacat gataagggtt aataagaatc
    22261 ctgcacgcca gaagaatttg atgaatttag gatagtaaaa gctgcgtttt ttcaaaagga
    22321 agaaaaagac gagaataatg gctaggatcg agagggttag ccccagtcta gggaggaaat
    22381 tatgggtaaa ggttttagct gtaatcaggt aatattcaaa taccaagacc ggaaaagcca
    22441 aatccgcaaa gtttcgtcct agttttttta atctaaaaag tttggttagg ataatgcaga
    22501 cgactaaggt cagtatcaat aataaaatag atgctaattt cattaaaatc atacccatat
    22561 tgtatcataa aaaaaggcta atggaaacga gaaacagagg aatttatagg aaagtcaggc
    22621 ttttgagatt gtgggtgatt tttgttataa tgaaagtcat gaaatcttat aataccttga
    22681 atgattatta tcgaaaactc tttggagaaa agacttttaa agtccctatt gatgcgggat
    22741 ttgactgtcc caatcgtgat ggaactgtgg ctcatggagg cagtactttt tgtacggttt
    22801 caggttctgg agatgctatt gtagccccag atgcgcctat ccgtgagcaa ttttataagg
    22861 aaattgactt tatgcaccgt aagtggccgg atgttcagaa gtatctggtt tattttcaaa
    22921 attttaccaa cacccatgaa aaggtggaag ttattcgaga gcgttatgaa caggctatca
    22981 atgagccagg tgtggtaggt atcaatattg gaacgcgccc agactgttta ccagacgaaa
    23041 ccatcgaata tttggctgag ttatcggagt gcatgcatgt gacggttgaa ttgggcttgc
    23101 agacaactta tgaagcaacc tctgacctga ttaaccgtgt gcattcttat gaattgtagg
    23161 tggaaacggt caagcgtttg agaaagtatc ccaagattga gattgtttcc catttgatca
    23221 atggtttgcc tggtgaaacc catgagatga tggttgaaaa tgtccgccgt tgtgtcacgg
    23281 ataacgatat tcaagggatt aaactgcatt tgctccatct tatgacaaat actcgtatgc
    23341 aacgagatta ccatgaggga cgtttacaat tgatgagtca ggacgaatat gtcagggtca
    23401 tctgtgacca actggaaatt attcccaaac atatcgtcat ccatcgaatt acaggagatg
    23461 cgcctaggga tatgctgatt ggtcctatgt ggagcctcaa aaaatgggaa gtcctcaaca
    23521 gcattgagat ggagatgcga cgtcgtggaa gtgttcaagg atgcaaggct gtaaaacagg
    23581 agtttgaaaa tgaaaagacc acttgagatg gcacatgatt ttttggctga ggtcgtgaca
    23641 aaagaggatg tcgtagtgga tgcgactatg ggaaatggtc atgacacgct ttttttagcc
    23701 aagctagcca agcaagtcta tgcctttgat attcagaagc aagccttgga aaagacccaa
    23761 gagcgtttgc atcaggctgg cttgacaaat gcccagttaa tcttgcaagg ccatgagaca
    23821 ctggaccagt ttgtgacaaa agctaaggca gggattttta atctgggcta tttgccgtca
    23881 gctgataagt ctgtcatcac ccgaccgcag acaacgattg aggcattaga aaagctatgt
    23941 ggcttacttg tcaaaggtgg acgaattgct attatgattt actatggtca tgaaggaggc
    24001 gacctcgaga gagatgctgt cttggatttt gtaatccagt tgaaccaaca agagtacaca
    24061 gctgccattt accgaacttt aaatcaagtc aacaacccgc cgtttttagt gatgattgaa
    24121 aaattagaga gatatagaca tggataaaca atacctacgt gaaaagctgg atgccatgcg
    24181 ccagaatttt gttgaatcaa cccaccacga acgagcggtg ggcgtgctag accaagcgca
    24241 tatgagcaaa aaaatgctta aaatcaagaa aaaattagtt gctcttgaaa tggaacggtg
    24301 ccagagaaaa attgagcaca aagactgttc caagattgac caaaaaatca aagagcagaa
    24361 ggagatattt gaatcctgtt gtaaaaaaga ttaaggagga cgtgcgtgga attactgatt
    24421 tacctcatcc tatttttact ggtcttgatt gtctcaagta caaccaataa gctcctgccc
    24481 tttttgcctc tccctttggt gcagattctt ttgggaattg tgattggtct ctttttaccc
    24541 aatactgact ttcatcttaa tacggagttg tttttggccc tggttatcgg acccttgctt
    24601 ttccgagagg ctgaagaagc agatgttacg gctattttaa aacactggcg aatcattgtt
    24661 tatctcatat ttccagtgat ttttatctcg accctgagtt tgggtggctt ggcccatctt
    24721 ctttggttca gccttccctt ggcagcttgc ttggctgttg gggcagccct tggtcctacg
    24781 gacttggtgg cctttgcctc tctttcggag cgttttagct ttcctaagcg cgtgtccaat
    24841 attcttaagg gcgaaggact cttgaatgat gcttctggtt tggtggcttt tcaggtagct
    24901 ttgacagctt ggacaactgg agctttttct ctggggcaag ctagcagttc gctcatcttt
    24961 tcaatcctag gcggtttttt aattggattt ttaacagcca tgaccaaccg cttcctccat
    25021 accttcttgc taagtgtgcg cgcaacggat attgccagtg aacttttatt agaattgagt
    25081 ttgcctctag tgaccttctt tctggcagaa gaagtccatg tttcagggat tattgccgtc
    25141 gtagttgctg gaattttaaa ggcaagtcgc ttcaagaaaa tcacgctcct cgaagcccaa
    25201 gtggatacgg tgaccgagac ggtctggcat acagtgacct ttatgctcaa cggttctgtc
    25261 tttgtgattt tagggatgga gttggaaatg atagcagaac ctatcttgac caatccaatc
    25321 tataatcctc tacttttatt gctatctctc atcgccctta cctttgtcct ctttgtcatt
    25381 cgttttatta tgatctatgg ctattatgcc tatagaaccc gacgcctaaa gaaaaagcta
    25441 aataagtata tgaaggacat gtttctcttg accttttcag gtgttaaggg aacggtgtcg
    25501 attgctacga ttctcttgat accaagtaat ctagaacagg agtatcctct cttgcttttc
    25561 cttgttgcag gtgtgacgct tgtcagcttt ttaacaggtc tcttggtctt gcctcatctt
    25621 tctgatgaag aggaagaaag caaggattat ctcatgcata tcgccatttt gaatgaagta
    25681 acgctagagt tggaaaaaga gttggaagac accagaaata aacttcccct ctatgcggct
    25741 attgacaatt atcatggacg tattgaaaat ctcattttaa gccaagaaaa ccaggatgat
    25801 caagaagact gggctgcttt gaaactctta attcttagta ttgaaagtga tggtttggaa
    25861 caggcctatg aagaggggaa cattagcaat cgtgcttacc gagtttacca acgttatctg
    25921 aaaaatatag aacaaggaat caatcgtaaa cttgcctcaa gactgaccta ttattttctt
    25981 gtttccttga ggattttacg ttttcttctt catgaagttt ttactcttgg aaagaccttc
    26041 cgtagctgga aggacaagga gcaaagccgt ctccgtgctc ttgattatga ccaaattgca
    26101 gagctctatc ttgccaatac agagatgatt attgaaagtt tggaaaacct gaagggagtc
    26161 tacagacgct ctttgattag ttttatgcag gagtctcgtc ttcgagaaac agctattatc
    26221 agcagtggtg cctttgtcga acgggttatc aatcgtgtca aacccaacaa tatcgatgaa
    26281 atgctgagag gctattatct ggagcgcaag ttgattttcg aatacgaaga aaaacgattg
    26341 attacgacta agtatgccaa gaaattacga caaaatgtaa ataacttaga gaactattcc
    26401 ttgaaggaag ctgccaatac cctgccgtat gatatggtgg aattggtaag aagaaattag
    26461 ttaatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttggatt atatatgtga
    26521 ctgacttcgt cagtttcatc tacaacctca aagcagggct ttgagcaacc tgcggctagc
    26581 ttcctagttt gctctttgat tttcattgag tataagattg taagtgaagg agtgtgacat
    26641 gaaaaaatgg tggaaagagc tgatagacaa gcctttatta aaagcttttt tgcattatta
    26701 tcaagcatca gatagtgagt tgaccagtgt cgcagtagcc tactattggt tgatttcgat
    26761 tttccccctg cttttggtgg tggtcaatat cctcccttat tttcagattc ctgtgggaga
    26821 atttctgggc tttatgaaag acgtcctgcc cccaagcctc tatgaaggtg tggaaaaaat
    26881 agccagagaa gtcttgacgc aaccttcaac aggtttattg agtttttctg ttttatcggc
    26941 gttatggagt ttttcaaaat ctatgaattt cttgcaaaaa gcttttaaca aggcttatgg
    27001 cgtcgaaaag agtcgtggac ttatttccca tcagatgctg agtctcctag tcagttttgg
    27061 cttgcagctc ctctttgcgt ttgccttgtt tttgatctta tttggtcaga tgattttggc
    27121 tttacttgct cattattgga caaaagatgg cattatctat caggctttac aagggttggc
    27181 aggtcctctg atttacgccc tcctctttgc tatcttggtc atgctttatt attttcttcc
    27241 caatctatct aacaggaaaa ttagctatac cctaccaggc agtgcctttg ttctcttagt
    27301 gattttaggt ttactaactc tgttctctag ttatctcaat tactatgtcc atcatttggt
    27361 ggatgtccga attttaggtt ccgttcttct tgttgttatg atgttttggt ttatcttgat
    27421 tgctaaaatt gttatcctag gcgcggttat caatgccagt atgcagagtt tgaaagatcc
    27481 ggtctttaaa aaagactaac tatttatcca ttataaaagc gcatagtatc aagactttat
    27541 agaaccttga tactatgcgc ttttgcgctt ttgtgctttg acagtttttt gtatagtttt
    27601 tgtccaagat ttctaaatca tctgattaaa ttcctatttt cccctatcat tgtccctgtt
    27661 ttttcgaaaa tggaaggagt ataataaatc tatcaataaa atgataggag gaactttatg
    27721 ggtcatattt tcttttttct aagtgtcttt ttggcaggga ttctatcctt cttttctcct
    27781 tgtatcttac ctttgttacc ggtctataca ggagtgttac tagatgataa ggatggtgct
    27841 caggcttcta gcggcaaatt ttcaatctca gttactagtt tattacgaac tctggccttt
    27901 atagcaggaa tttcctttat atttattttg ttgggctatg gagctggttt tttaggcgat
    27961 ttgctttatg cttcttggtt ccaatatctt actggggcaa ttattatcct tcttggtttg
    28021 caccaaatgg agattctaca ctttaagggg ctttataagg aaaagaggct acaactgcaa
    28081 ggacaggggc aaaatggtaa gggctatagt caggcatttt tattgggctt gacctttagt
    28141 tttgcttgga cgccttgcgt ggggccggtt ctggggtctg ttttggcctt ggcggcttca
    28201 ggtggttcag gagcttggca gggagctggt ctcatgttgg tgtatacgct gggcttggcg
    28261 ctaccattct tgcttctagc tctgacctct agttatgttt tgaaacattt ccgaaaactt
    28321 catccctatc tcggaatcct caaaaaagtg ggtggttttc tcattattgt gatgggactc
    28381 ttggttctgt ttggaaatgc ttcaatttta agtcaattat ttgaataaaa tggaaaggaa
    28441 tatcaatatg aaaaaatggc aaacatgtgt tcttggagca ggttcgctcc tttgtttgac
    28501 ggcttgttca ggcaagtccg tgactagtga acaccaaacg aaagatgaaa tgaagacgga
    28561 gcagacagct agtaaaacaa gcgcagctaa agggaaagag gtggctgatt ttgaattgat
    28621 gggagtagat ggcaagacct accgtttatc tgattacaag ggcaagaaag tctatctcaa
    28681 attctgggct tcttggtgtt ccatctgtct ggctagtctt ccagatacgg atgagattgc
    28741 taaagaagct ggtgatgact atgtggtatt gacagtagtg tcaccaggac ataagggaga
    28801 gcaatctgaa gcggacttta agaattggta taagggattg gattataaaa atctcccagt
    28861 cctagttgac ccatcaggca aacttttgga aacttatggt gtccgttctt acccaaccca
    28921 agcctttata gacaaagaag gcaagctggt caaaacacat ccaggattca tggaaaaaga
    28981 tgcaattttg caaactttga aggaattagc ttaggaggtg tcttatgaat gataagttaa
    29041 aaatcttctt gttgctagga gtattttttc tatccataac cggtttctat gttctattga
    29101 tacgaaatgc agggcagaca gatgcctcgc aaattgaaaa ggcggcagtt agccaaggag
    29161 gaaaaacagt gaaaaaaaca gaaattagta aagacgcaga cttgcacgaa atttatctag
    29221 ctggaggttg tttctgggga gtggaggaat atttctcacg cgttcccggg gtgacggatg
    29281 ccgtttcagg ctatgcaaat ggtagaggag aaacaaccaa gtacgaattg attaaccaaa
    29341 caggtcatgc agaaaccgtc catgtcacct atgatgccaa gcaaatttct ctcaaggaaa
    29401 tcctgcttca ctatttccgc attatcaatc caaccagcaa aaataaacaa ggaaatgatg
    29461 tggggaccca gtaccgtact ggtgtttatt acacagatga caaggatttg gaagtgatta
    29521 accaagtctt tgatgaggtg gctaagaaat acgatcaacc tctagcagtt gaaaaggaaa
    29581 acttgaagaa ttttgtggtg gctgaggatt accatcaaga ctatctcaag aaaaatccaa
    29641 atggctactg ccatatcaat gttaatcagg cggcctatcc tgtcattgat gccagcaaat
    29701 atccaaaacc aagtgatgag gaattgaaaa agaccctgtc acctgaggag tatgcagtta
    29761 cccaggaaaa tcaaacagaa cgagctttct caaaccgtta ctgggataaa tttgaatccg
    29821 gtatctatgt ggatatagca actggggaac ctctcttttc atcaaaagac aaatttgagt
    29881 ctggttgtgg ctggcctagt tttacccaac ccatcagtcc agatgttgtc acctacaagg
    29941 aagataagtc ctacaatatg acgcgtatgg aagtgcggag ccgagtagga gattctcacc
    30001 ttgggcatgt ctttacggat ggtccacagg acaagggcgg cttacgttac tgtatcaata
    30061 gcctctctat ccgctttatt cccaaagacc aaatggaaga aaaaggctac gcttatttac
    30121 tagattatgt tgattaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac
    30181 cgtatgtagg gttactgact ccgtcagttt tatctacaac ctcaaagcta tactttgagc
    30241 tgacttcgtc agttttatct acaacctcaa agcggtactt tgagaaacct gtggctatct
    30301 tcctagttta ctttttgatt tttattgagt ataagaggtc tttcctaagc agttagagga
    30361 gaattttgct atactgatac tagtaagtgg taaaggagca gagcatgacc tacacaatct
    30421 taatcgtaga agatgaatat ctggtaagac aaggtttgac taaactggtc aatgtagcag
    30481 cctacgatat ggaaatcatc ggtcaggctg aaaatggaag gcaggcttgg gaattgatcc
    30541 aaaagcaggt tccagatatc attttaaccg atatcaacat gcctcatcta aatggcatcc
    30601 agttggccag tctggtacga gaaacctatc ctcaggttca tttggtcttt ttaacaggtt
    30661 acgatgattt tgattatgcc ttgtctgctg tcaaactagg tgtggacgac tacctgctca
    30721 aacccttttc tcgtcaggat attgaggaaa tgttggggaa aatcaaacaa aaactagaca
    30781 aggaagagaa agaagagcag ttacaagatt tattgactaa taggtttgaa ggaaacatgg
    30841 cccagaaaat ccagtctcat ctggctgata gccaatttag tttaaagtct ttagccagtg
    30901 acttaggttt tagtccgacc tatctgagtt ccttgattaa gaaagagttg ggcttgcctt
    30961 ttcaggatta tctagtgaga gaacgtgtta aacaagccaa gctcttgctt ttaactacag
    31021 atctgaagat ttatgagatc gcagagaagg ttggttttga agatatgaac tattttaccc
    31081 aacgttttaa gcagattgca ggtgtgacac ctcgtcagtt taagaaggga gaagaccgat
    31141 gaagcgttct tctcttttag ttagaatggt tatttccatc tttctggtct ttctcattct
    31201 cctagctctg gttggaactt tctactatca atcaagttct tcagccattg aggccaccat
    31261 tgagggcaac agccaaacga ccatcagcca gactagccac tttattcagt cttatatcaa
    31321 aaaactagaa accacttcga ccggtttgac ccagcagacg gatgttctgg cctatgctga
    31381 gaatcccagt caagacaagg tcgagggaat ccgagatttg tttttgacca tcttgaagtc
    31441 agataaggac ttgaaaactg ttgtgctggt gaccaaatct ggtcaggtca tttctacaga
    31501 tgacagtgtg cagatgaaaa cttcctctga tatgatggct gaggattggt accaaaaggc
    31561 cattcatcag ggagctatgc ctgttttgac tccagctcgt aaatcagata gtcagtgggt
    31621 catttctgtc actcaagaac ttgttgatgc aaagggagcc aatcttggtg tgcttcgttt
    31681 ggatatttct tatgaaactc tggaagccta tctcaatcaa ctccagttgg ggcagcaggg
    31741 ctttgccttc attatcaatg aaaaccatga atttgtctac catcctcaac acacagttta
    31801 tagttcgtct agcaaaatgg aggctatgaa accctacatc gagacaggtc agggttatac
    31861 tcctggtcac aaatcctacg tcagtcaaga gaagattgca ggaactgatt ggacggtact
    31921 tggcgtgtca tcattggaaa agttagacca ggttcggagt cagctcttgt ggaccttgct
    31981 tggggccagt gtcacatctc ttcttgtctg tctctgctta gtgtggttca gtcttaaacg
    32041 ctggattgct cctttgaagg atttgagaga aaccatgttg gaaattgctt ctggtgctca
    32101 aaatcttcgt gccaaggaag ttggtgccta tgaactgaga gaagtaactc gccaatttaa
    32161 tgccatgttg gatcagattg atcagttgat ggtagctatt cgtagccagg aagaaacgac
    32221 ccgtcagtac caacttcaag ccctttcgag ccagattaat ccacatttcc tctataacac
    32281 tttggacacc atcatctgga tggctgaatt tcatgatagt cagcgagtgg tgcaggtgac
    32341 caagtccttg gcaacctatt tccgcttggc actcaatcaa ggcaaagact tgatttgtct
    32401 ctctgacgaa atcaatcatg tccgccagta tctctttatc cagaaacaac gctatggaga
    32461 taagctggaa tacgaaatta atgaaaatgt tgcctttgat aatttagtct tacccaagct
    32521 ggtcctacaa ccccttgtag aaaatgctct ttaccatggc attaaggaaa aggaaggtca
    32581 gggccatatt aaactttctg tccagaaaca ggattcggga ttggtcatcc gtattgagga
    32641 tgatggcgtt ggcttccaag atgctggtga tagtagtcaa agtcaactca aacgtggggg
    32701 agttggtctt caaaatgtcg atcaacggct caaacttcat tttggagcca attaccagat
    32761 gaagattgat tctagacccc aaaaagggac gaaagttgaa atatatataa atagagtaga
    32821 aactagctaa ctcccagtta attctgggag ttttatgcgt aattgggcaa actttatagg
    32881 ttgtctatct tgctaaaaac aagaaaaaac ggtatgatag aagagtgaca acagaggtaa
    32941 cagagatgaa cgagacacag attcaaagag aaacacgtca ggtagtggaa gatgttttag
    33001 aaaagaccaa tttgaagcag ggggtccttt ttgttttagg tctatcttct agtgaggtgc
    33061 taggtggtca gattgggaaa gaatccagtc aagagattgg tgagctgata gtggagacta
    33121 tcttgggtat tctaggtagt agaggtatcc atttagcagt tcaaggttgt gagcatgtca
    33181 atcgggctct cgttgttgaa cgtcaggtgg cagagcagtt tgatctggaa attgtcagtg
    33241 tccatcctac tcttcatgca ggaggttcgg ggcagttggc agcctttaag tttatgcagg
    33301 atccagttga ggttgaattt atcaaggctc atgctggatt ggatatcgga gacactgcaa
    33361 ttggcatgca tgtcaagcat gttcaggttc cgattcgccc tattttgaga gagattggtc
    33421 atgcccatgt aacggcactg gctagtcgtc caaaattaat cggaggtgcg cgtgcgcact
    33481 atccgcaaga cgctattaga aagtcttgag aatgaataaa ggagataaaa gtgtttaaaa
    33541 aagaccgttt ttcaattcgt aagattaagg gagttgtagg ctctgtattt cttggaagcc
    33601 ttttgatggc tccttctgta gtggacgcag ccacctatca ctatgtaaat aaagagatta
    33661 tttcacaaga agctaaagat ttaattcaga caggaaagcc tgacaggaat gaagttgtat
    33721 atggtttggt gtatcaaaaa gatcagttgc ctcaaacagg gacagaagca tctgttttga
    33781 cagcttttgg tttgctgact gttgggagct tgcttttaat ctacaagaga aagaaaattg
    33841 ctagcgtctt tctagttgga gctatgggat tggtagttct tcctagtgca ggggctgtag
    33901 acccagttgc gaccctagcg ctggctagtc gagagggtgt tgttgaaatg gatggctatc
    33961 gctatgttgg ttatctatca ggtgacatcc tcaaaacgct tggcttggac actgttttag
    34021 aagaaacctc agcaaaacct ggagaggtga ctgtagtcga agttgagact cctcaatcaa
    34081 caacaaatca ggagcaagct aggacagaaa accaagtagt agagacagag gaagctccaa
    34141 aagaagaagc acctaaaaca gaagaaagtc caaaggaaga accaaaatcg gaggtaaaac
    34201 ctactgacga cacccttcct aaagtagaag aggggaaaga agattcagca gaaccatctc
    34261 cagttgaaga agtaggtgga gaagttgagt caaaaccaga ggaaaaagta gcagttaagc
    34321 cagaaagtca accatcagac aaaccagctg aggaatcaaa agttgaacca ccagtagaac
    34381 aagcaaaagt cccagaacaa cccgtgcaac ctacacaagc tgagcaacca agtacaccaa
    34441 aagaatcatc acaacaagaa aatcctaaag aagatagggg agcggaagag acaccgaaac
    34501 aagaagatga acagccagca gaagccccag aaatcaaggt tgaagaacca gtagaatcaa
    34561 aagaggagac tgttaatcaa cctgttgaac aaccaaaagt ggaaacgcct gctgtagaaa
    34621 aacaaacgga accaacagag gaaccaaaag ttgaagtaac aagtattccc caaactactc
    34681 gctatgagga agaccttact aaggaacacg gaacgcgtga agttgttaag gaaggtaaga
    34741 atggcagtag aacagttact actccatata tcttgaatgc gacagatggt acgactacag
    34801 aaggcacttc gacaactgat gaagctgaga tggagaaaga ggttgttcgt gttggcacga
    34861 aacccaaaga aaaattagct ccagtcttaa gtttgacaag tgttacagat aatgcaatgt
    34921 tgcgtagtgc gagacttact tatcatttgg aaaatacaga tagtgttgat gtgaaaaaaa
    34981 ttcatgctga aattaaaaat ggcgataagg ttgtcaaaac tattgactta tctaaagaga
    35041 gattatcaga tgctgttgac ggtcttgaac tttataaaga ttataagatt gtgacgagta
    35101 tgacctatga tagaggtaat ggtgaagaaa cctctacgtt ggaagaaact ccactacgat
    35161 tagacctcaa gaaggttgaa ttgaaaaaca tcggctctac taatctcgtc aaagtaaatg
    35221 aggatggtac tgaggtggca agtgacttct taacaagtaa acctgtggat gtgcagaatt
    35281 actacctcaa agtaacttca cgtgataata aagtgtttcg cctcacagtt gaaaaaattg
    35341 aagaggtgac tgaggaaggt caaccacttt acaaagtcac tgctaaggct cctaatttga
    35401 ttcagcacac ggatgcgact aaaatgcaag acgaatacgt gtattatatt gaaaaaacac
    35461 gtgcaacaga tggtgatatt tactacaact ttaacgactt agtaaacgcc atgaacaaaa
    35521 acaaaactgg tacattcaaa cttggtgctg atttgaacgc tacaggtgta ccgacacctg
    35581 ctaagtcgta tgttacaggt gatttccgag gtactttgac aagtgttgat ggtgaacatt
    35641 acacaattca taatacaagt cgcccattgt ttaataatat tataggtggg actatcaaag
    35701 atattaacct tggcaatgtt aatattcaca tgccatgggc aaataacgtt gcatcgttag
    35761 ctaatattat taaaggtgga accactattg aaaatgtcaa agttacaggt aatgttcttg
    35821 gtaaagactg ggtatctgga tttatagata aaatagatag tggcggtaca ttgagaaatg
    35881 tagcttttat tgggaatgtg acctctgttg gtacaggtgg ttcgttcttg actggtattg
    35941 ttggtgaaaa ctggaaggga ctggtagaac aggcttatgt agatgccaat attcgaggga
    36001 agaaagctaa ggctgcaggt atagcttact ggtcgcaaaa tggaggcgat aactatgctg
    36061 taggtagata tggagcaatt aagaaatctg tcgttaaagg ttcaatagat gtagaaaaac
    36121 caattgaagt tggtggcgct gttggaagtt taaattatct tggttatata gaagacactg
    36181 ttgctatgat gaaagttaag aacggtgaaa ttttctacgg ttcgcatgat atcgataccg
    36241 atccatatta cacaggagaa cgagtaaata gaaatttcat tgttgacggt gtaagtgaag
    36301 gtaaatcttc gtataaatac tctaaacaac aaaatcgcat taaatcagta tctcaagagg
    36361 aagctgataa gaaaattaaa gaattggcta tcacagcaga taaatatgca attacagagc
    36421 caattgtaaa taaactcaac gctctcacaa cacgtgataa tgagtataga acaacacaag
    36481 attacaaagc agaccgtgaa cttgcttatc gtaatatcga aaaacttcaa ccattctaca
    36541 ataaagagtg gattgtagac caaggtaata aagttccatc aaattctaaa ttattaacta
    36601 cagaagtatt atctgttaca ggtatgaaag atggtcaatt tgtgactgac ttatcagaaa
    36661 ttgataaaat tatgattcac tatgcggatg gcaccaaaga agaaatgaac gtgacagcgg
    36721 ttgctgattc taaggtgaaa caagttcgtg agtatgacgt gactgatttg ggtgttgttt
    36781 acactccgaa tatggttgat aaaaaccgcg accaattgat tgcagatgtg aaagcgaaat
    36841 tgtcgtcagt tgaattgatt tcccctgaag ttcgtgctct tatggataaa cgtggtaaag
    36901 ctgaagaaaa tacggaaggt cgtcaaaatg gatacattag agatctattc cttgaagaaa
    36961 gctttgctga agtgaaagct ggtttgggta aattggttaa agctttggtt gaaaacgaag
    37021 attatcaatt aaatagcgat gaagcagcaa tgcgcgcgtt aattaagaaa gttgaagaca
    37081 ataaagctaa aatcatgatg ggactggcct acttaaatca atattatagt tttaaatacg
    37141 ctgagttatc aattaaagat attatgatgt ttaaacctga tttttatggt aagaatgtta
    37201 atgtcttaga tttcttaatc aaaattggtt caagtgaaag aaatgttaaa ggtgatagaa
    37261 ctttagaagc ttatcgtgaa actatcggtg gaacaattgg aataaatgaa ttaaatggat
    37321 tcttacatta caatatgaag ctatttacta accatataga tataaatgac tggtttaaga
    37381 aagctattga aaagaatgct tatgtagttg aacaaccatc aacgaaccct gcatttgcca
    37441 acaaaaaata tcgtctatac gaaggaatta ataatgggca acatgggcgg atgattttac
    37501 ctcttcttaa cttgaaaaat gcacatctat ttatgatttc aacatacaac actatctcgt
    37561 ttagttcgtt tgaaaaatat ggcaaagaca cagatgaaaa acgtgaaaag tttaagagtg
    37621 agatcaataa acgtgctaaa gagcaggtta attacttaga tttttggtca cgtcttgcta
    37681 ctgataatgt ccgtgataaa cttcttaaga gtcaaaatgt agttccaact cctgtatggg
    37741 ataatcataa tagcccgaac ggatgggcta gtagacatgg tcatatagat gggaaaccgg
    37801 attatgctcc aattcgtgag ttctttgggc gaatcaataa gtatcatggt tacaaatatg
    37861 gatatggcgc atatgcatat atttttgcag cacctcaacc gatggatgca gtttatttcg
    37921 ttatgacaga tttaattagt gactttggaa catctgcatt tacacatgaa actactcaca
    37981 ttaatgatcg tatggcttac tatggtggtc attggcatcg tgaaggtacg gatcttgaag
    38041 catttgctca ggggatgtta caaacgccat cggtatcaaa tccaaacgga gaatatggcg
    38101 cattaggtct aaatatggcg tatgaacgtc aaaatgatgg aaatcaatgg tataatccaa
    38161 atcctaacaa acttaaatct cgcgctgaaa ttgatcacta catgaagaac tacaatgaag
    38221 ctcttatgat gttagattat ctggaagcag aatctgtttt acctaaatta aaaggtaaca
    38281 atgatagatg gttcaagaaa atggataaac aaatgcgtaa ggacggacaa cctcaccagt
    38341 ttgacaaaat tcgcgattta aataatgaag agaagaaaat tcaattagct tctattgagg
    38401 atttagttga taataacttt atgactaaac acggtgctcc tggaaatggt acatataacc
    38461 catcagattt tagttcagca tatgttaata tgaatatgat gactggtgta tacggaggta
    38521 actcaagtga tggggctcct ggcgctgctt catttaaaca taatactttc cgtatgtggg
    38581 gatacttcgg atacgaaaat ggattcatcg gatatgcctc taataaatat aaagccgaag
    38641 ccaataaagc aggtcaaact ctaagtgata aatatatcat caataaagtt tctggtggta
    38701 catttaatac acttgaagcg tggaagaaag aatggtttaa acaaatcaaa actaaagctc
    38761 aaaaaggatt cacagcaatt gaaattgatg gtaaaactat tgattcatat gaaaaattaa
    38821 aagacttatt tgataaagct gttgaagaag atcttaaagg aactggaacg gataagactg
    38881 tgaaacttaa agaaaaagta tacaaacaac tccttaaaaa cacagacggt ttctctggtg
    38941 atctatttac tgcaccacaa gcatagaatg aataaaatcg gaaaaaggta gatcagcttt
    39001 gtctgtatct gcctttttat gctatactta aggtatgcat agaaaaacag tgattgattt
    39061 taggacttta ggggagagat atacctttac ccagcctatt aaagagttga aaacgagaaa
    39121 tgtagcagaa gtggcagatt tgctggcaca agtggaaagc taccaagagc aagattatta
    39181 tgtggtgggg tatgtcagct acgaggctgc acctgctttt gaggagaaat tagcagttca
    39241 caaggttcct ctactgggcg agtacttgct ttactttact gttcacgata gggtggagac
    39301 ctcccctatt cctctgactt atgaggatat tgatttgccc tcaaattggc aggaagtaac
    39361 gtctgcagag aactatgaaa aggccattgc ccagatacac catcacttga ggcagggaga
    39421 cacctatcag gtcaactaca ccgtccaact caagcaaaag ttaagtgcca atccttttgc
    39481 catctacaat cgtatggtgg tagagcagga ggcgggctac aatgcctatg tggaacatga
    39541 cgagatggca gtgatttcca tgagcccaga gctctttttt gagcaaaatg atcgcgagtt
    39601 gacaacacga ccaatgaagg ggacgactca gcgtggggta actgaccaag aagatcttga
    39661 acaggccagt tggttgggac aggatcccaa aaatcgctct gaaaatatga tgattgtgga
    39721 cctcttgcgc aatgatatga accgtatttc tgaagttggg agcgagcacg tggagcgtct
    39781 gtgtcaggta gagcagtatt caactgtttg gcagatgact tcgaccatca agagtcagtt
    39841 gcgagaggat gtggaccttg ttgaaatctt ccgctcactc tttccttgtg gttccataac
    39901 gggtgcaccg aaaattgcga caatggagat tatcaaggac ttggagcctc aaccgcgtgg
    39961 agtctactgt ggaacgattg gtctcttgct tccaaatgga cgacggattt ttaatgtggc
    40021 cattcgtacc attcaacttc acaaaggtca agcaatttat ggagttggcg gagggattac
    40081 ttgggatagc acatgggaat ctgaataccg agaggttcat caaaaggcag cagttcttta
    40141 tcgtaaacaa gctcgcttcc aactgattac gacaggggaa atcagccaga agaacctgct
    40201 gtttgaagat caacatctgg aaagactgag aaaagccagt cgttattttg cctttccttt
    40261 tgatgcagaa gacttgggac acaagattga ggaagagtgt caggattgtg aagctaatca
    40321 agattaccgc ttgcgaatca gccttagcaa atctggagag atagaagtca atcgtcaagt
    40381 attaacccct ctcagtacaa gcttttgtca ggcccaagtc tgtcttcagg aagctgcttt
    40441 gaatcaatcc tttacctact ttaaaaccac tcaccgaccg catttgagcc taggagaaca
    40501 agagaagatt taccacaata agtcaggaga actgcttgaa acctctatag gaaatttggt
    40561 tctgaaaatc gctggaaaac tctacacacc gcctatccga cttggaatct tgccaggaat
    40621 ttaccgtcag catttgctag aaacaggaca ggtagaagag aaagtcttga ccttggcaga
    40681 tttaacccaa gcagaagcta tttacggctg taatgcagtg agaggcttgt atgaactaag
    40741 ccttgaggag aactagatga aattgatatt tttgcatggg ttagggcagt cagcagagtc
    40801 ttggaaagaa gttcggaatc tactgacaga ttatccttct gaggctatcg agttatttcc
    40861 ttctggagtt agtaactatc aacaagctaa agagcgagtt tatcagcacc tagctcaaga
    40921 gacagaacct tttgttttga ttggattgtc cttaggtgct accctgacac tagaactttc
    40981 cagttacgat ttaccaaatc ttcgagcttt gattctgtca ggatgcccgc ttaaattagc
    41041 agggaatatc ctattttatc ttcaattgct gatttttaaa ctacttccca aaagagtatt
    41101 tgaaaaacag ggagcagaca agactcttat ggtcggagtt tctgaggaat tgaagacact
    41161 tgatttaacg gatatagcag ggacttgctc ctatccaacc ttactaattt gtggcagcaa
    41221 agataaaccg aatcttagtt ctatgaaagc tctccataga ctgttaacag attcgcagtt
    41281 tcagatcatt cctgatggcc ctcatgtctt gaataaggca aaaccaaagg agtttgtaga
    41341 aaagaccaga agtttccttg aattgctgaa ataagtttga taaaataata ttgaaatcga
    41401 tatcataatt atgggagaaa gaaatgaata aacgtctatt tttaaaaatg agtctggtga
    41461 cgttgccaat tttagccttg ttttcacaac cagttttggc ggaagaaaac atccattttt
    41521 cgagctgtaa ggaagcttgg gcgaatggct attcggatat ttacgaggga gaacctggtt
    41581 attctgccaa gttagaccgt gatcatgatg gtgtggcttg cgaattgaaa aatgctccta
    41641 agggtgcttt taaagcaaaa cagtcaacgg ctattcaaat caacacaagt tcagcaacaa
    41701 caagtggttg ggttaagcag gacggcgctt ggtactactt tgatggaaat ggaaatctag
    41761 tgaaaaatgc atggcaggga agctattacc tgaaagctga tggtaaaatg gcacagagtg
    41821 aatggattta tgactcttct tatcaagctt ggtattattt gaaatcagat ggttcttatg
    41881 caaaaaatgc atggcaagga gcttattacc ttaaatcaaa cggtaaaatg gtacaaggtg
    41941 agtgggttta tgattcttct taccaagcat ggtattactt gaaatcagat ggttcatatg
    42001 ctcgcaatgc atggcaagga aactactatt tgaaatcaga tggtaaaatg gctgtcaatg
    42061 aatgggttga tggtggacgt tattatgttg gcgctgacgg agtttggaag gaaggtcaag
    42121 caagtacagc ttcttctagt aatgatagca atagtgaata ttctgctgct ttaggaaagg
    42181 caaaaagtta taattcgtta ttccacatgt caaaaaaaac gtatgtatag acaattaact
    42241 tctgattttg ataaattttc aaatgatgca gctcaatatg ccattgatca ttagatgatt
    42301 aacagatact ggtaggcgaa aaaattcctt ataattcatt tacgcaaacc tttgcataag
    42361 tgaatggatt ttgatatact agtactgtaa gcattttcaa ttactacaca atgaaaaagg
    42421 agaatatgat gagtcaaaag attattggga ttgaccttgg tggaacttct atcaaatttg
    42481 caatcttaac aacagcagga gaaatccaag gaaaatggtc aatcaagacc aacattttgg
    42541 atgagggaag tcatatcgtt gatgatatga ttgagtctat tcaacatcgt ttggacttgc
    42601 ttggattggc agcagcggac ttccaaggca ttggaatggg atcaccaggt gtggttgacc
    42661 gtgacaaagg gactgttatc ggtgcctaca acttgaactg gaaaaccctt caaccaatca
    42721 aacaaaagat tgaaaaagct ttgggcattc catttttcat cgataatgat gccaacgtag
    42781 cagctcttgg tgagcgctgg atgggtgctg gagataacca accagacgtt gtctttatga
    42841 cactcggtac tggtgttggt ggcggtatcg tcgcagaagg caaattgctt cacggtgttg
    42901 ctggtgcagc aggtgagctt ggtcacatca ctgttgactt tgaccagcca atctcatgta
    42961 cttgcggtaa gaaaggctgc cttgagacag ttgcttcagc aacagggatt gtcaacttga
    43021 ctcgtcgcta tgccgatgaa tacgaaggcg atgcagcctt gaaacgcttg attgataatg
    43081 gagaagaagt aactgctaag actgtctttg atctcgcaaa agaaggagac gaccttgctt
    43141 tgattgttta ccgtaacttc tcacgttact tgggaatcgc ttgtgctaac attggttcaa
    43201 tcctaaaccc atcaacaatc gtcatcggtg gtggtgtgtc agctgcggga gaattccttc
    43261 tacaaggtgt tcaaaaagtt tacgatgaaa atagtttccc acaagtacgc acatctacta
    43321 aattagctct tgcaactcta ggaaatgacg ctggagttat cggagcagca tcacttgtat
    43381 tgcaataaga taatgagaga ggaaaatgct aacctagagt tagtaatgtt cctcttttat
    43441 tttttatgct atactagtta ggacaatgaa tgaggtgaga gtaaatgaca aaagcagata
    43501 cgatttttaa agagaatatt gaatgcattc taaaggaagg tgttttctca gagcaagctc
    43561 gtcctaagta caaggatggg actgttgcta attccaagta tgtaactggt gccttttccg
    43621 agtacgactt atctaaagga gaatttccta tcacaacctt gcgtcccatt gcaatcaaat
    43681 ccgccatcaa agaagttctc tggatttatc aagaccagtc aaatagctta gaagtgctta
    43741 atgacaagta caatgttcac tactggaatg actgggaagt tggagacacg ggaaccattg
    43801 gtgagcgcta tggtgccgtt gttaagaaac acgacattat caataagctt ctcaaacagt
    43861 tggaaaccaa tccttggaat cgccgcaata ttatttcgct ctgggattac caagctttcg
    43921 aagaaacaga tgggctgctc ccgtgcgcct ttcagaccat gtttgatgtc cggcgtgttg
    43981 atggggaaat ctatctggat gcgaccttga cccagcgctc caatgatatg ctggtggccc
    44041 accacatcaa cgctatgcag tatgtggctt tgcagatgat gattgccaaa cattttggct
    44101 ggaaggttgg gaagttcttc tatttcatca acaacctcca tatctatgat aatcaatttg
    44161 aacaagctca ggaattgctc cgtcgggagc cgtcaaactg ccaaccacgc ttggttttaa
    44221 atgttcctga tgggactaat ttctttgata tcaaagcaga agattttgag ttggtggatt
    44281 atgaccctgt taagccacag ttgaagtttg acctagctat ttaaaagaat agaaaaaaga
    44341 agttgagaat aatcccaact tcttttgttt cttaacgtga tacgcggcga cgagctgctt
    44401 ttttacgatt ttcttcgatg aaagctgctt tttgctcttc tggttcgatt actttctttt
    44461 taaatgcgta tactgcacct gcaacggcag cgacagttcc tgcgacacct gttacaagac
    44521 ctttagcgaa tcctttagcc atgagtcttc ctcctttata ttctcaatca gccagcctcc
    44581 tcaagaggtc acatttttct gactgacctt tttgtgttat aataatagta acgaaaaaat
    44641 gggaattttt caaggaaaaa agatgaaaac aaaaataatt gtgattgttg gaccgactgc
    44701 tgttggaaag acggctctag ctattgaagt tgcaaagcgc tttaatggcg aagtggttag
    44761 tggagatagc cagcaagtct atcgaggact tgatattggg acggccaagg ctagtccaga
    44821 agagcaggca gctgttcctc atcatttaat cgatgttaga gagataaccg agtcttactc
    44881 ggcttttgat tttgtttcag aagctaagat gactattgag gatattcaca gccgtggcaa
    44941 gctagccatt atcgccggtg ggactggact ttatatccag agcttgctag aaggttacca
    45001 cctaggtggg gagactcctc atgaggagat tttagcttat cgagctagtt tggagccata
    45061 ttcagatgag gaattagccc atttggtgga gcaagcaggc cttgagattc cccagtttaa
    45121 tcgtcgtcgt gctatgcgtg ccttagaaat tgcccatttt ggtcaggatt tggaaaatca
    45181 agagatcttg tatgaaccgc tgattatctg cttggatgat gaacgtagtc aactttatga
    45241 gcgtatcaac caccgagtgg atttgatgtt tgaggctggg cttttggatg aggccaagtg
    45301 gctgtttgac cattccccta atgtacaggc tgctaaagga attggctata aggaactctt
    45361 tccttatttc cgtggagagc agacctttga ggaagctcgt gagagtctta aacaggcgac
    45421 ccgtcgtttt gccaagcgtc agctgacctg gttccgtaat cgcatgcagg tcacctttta
    45481 tcagattgga gaatctggtg tacaagaccg cattttaagc cagatagagg agtttttaga
    45541 tgattgaaac ggagaaaaaa gaggagcgag tcctgctgat tggtgtggaa ttgcagggta
    45601 tggacagttt tgacctctcc atggaagaat tggctagttt agcgaaaacg gcaggggcag
    45661 tcgttgtaga tagctacaga caaaaacgtg aaaaatatga ttccaagacc ttcgtcggct
    45721 ctggtaagtt ggaagagatt gcgcttatgg tggatgcaga agaaatcact actgtcatcg
    45781 tcaacaaccg tctgacccca aggcagaatg tcaatctaga ggaagttctc ggtgttaagg
    45841 tcattgaccg tatgcagttg attttggata tctttgccat gcgggctcga agccatgaag
    45901 ggaagctcca agtccaccta gcccaactca aatacctctt gcctcgcttg gttggtcagg
    45961 ggattatgct cagccgtcag gcagggggaa ttggttcccg tggtcctggt gaaagccagc
    46021 tggagctgaa ccgtcgtagc gttcgcaatc aaatcacgga tatcgagcgc cagctcaagg
    46081 tggttgagaa aaatcgggcg actgtcagag aaaaacgttt ggagtctagc acctttaaga
    46141 ttggtttgat tggttatacc aatgctggga aatcaactat catgaacatc ttgaccagta
    46201 agacccagta tgaagcagat gagctctttg cgactctgga tgcgacaacc aagagtattc
    46261 atctgggagg caatctccaa gtaactttga cagataccgt tggctttatt caagatttgc
    46321 cgacagagtt ggtgtccagt ttcaagtcaa ccttggaaga aagcaagcat gtggaccttc
    46381 tggttcatgt tatcgatgct agcaatcctt accacgagga gcatgaaaaa acggttctct
    46441 ccatcatgaa agacctggac atggaagata ttcctcactt gacgctttat aataaagcgg
    46501 atttggtgga ggatttcacg cctacccaaa cgccatatac cctcatttct gccaagtctg
    46561 aggacagtcg tgaaaacttg caagcattat tgctagataa gattaaggaa atttttgaag
    46621 catttaccct gcgagtgcct ttttcaaagt cctacaagat tcatgattta gagagtgttg
    46681 caattctgga agaacgtgat tatcaggaag acggcgaagt gattacaggc tacatttccg
    46741 agaaaaataa atggaggtta gaagaatttt atgactgata ttaaaacttt ggctctaaag
    46801 tatggaggtt atacaagtct ggacaaggtc tatctggatc agcttctagc tggtaaaaca
    46861 gagcaggagc agttaacact tattacacct ccgccaagtg ttgttaatgc ctactttgca
    46921 gaactctatc agaaaaaaag tcctcaggct gcgacggatt attttgcaga actcagtcag
    46981 gaactgaatc tttacaatac tgagccaagt ttcaccctag aaaataagcc ttttattcgg
    47041 cttaatctgt ctggtaaatc ctttggtttt tgttatgaga gtgacggctt tggtcggatt
    47101 ttctctgaaa atgaggagaa aatctcggat gacttgctct ttgaaattgc gcaaattttc
    47161 tcccatcaat tagtctttga agagtctggt aagatttaca tgaagcctgt caaggacgag
    47221 gaagttgtca gcctagaaag tctcacagct ttgactgatt tggaaagatt ggctgatggt
    47281 cgaaaacgtc tcaaaggcta cagccaagag gatttattgc aagaagctgc tgctttttct
    47341 ggcaaacgct atttccgatc ggaaaaccgc acagccatgt tatatattga ttaattagaa
    47401 agtatcgaat ggatattcaa tttttaggaa cgggggctgg tcagccctct aaagcccgca
    47461 acgtttcaag tctcgccctg aaacttttgg acgagattaa cgaagtttgg ctctttgact
    47521 gtggagaagg tacgcaaaat cgcattctgg aaaccacaat tcgaccacgt aaggtcagca
    47581 aaatctttat tacccatctg catggagacc acatttttgg tttgccaggt ttcctttcta
    47641 gccgtgcctt tcaggccaat gaagagcaga cagatttgga aatctacgga cctcaaggaa
    47701 tcaagtcatt tgtcttaacc agccttcgtg tgtcaggttc tcgtctgccc taccgcattc
    47761 atttccatga gtttgaccaa gattctctgg gtaaaattct tgaaaccgat aaattcactg
    47821 tgtatgcaga ggagctggac cacactattt tctgtgttgg ctatcgtgtc atgcaaaagg
    47881 atctagaagg gacgctggat gctgaaaaac tcaaggctgc tggtgttccg ttcggcccgc
    47941 tttttggtaa aatcaaaaac ggccaggatc ttgttttgga agacggaact gaaatcaagg
    48001 cagcagacta tatctcagcg ccacgtccag gtaagattat cactatttta ggagacactc
    48061 gaaaaacgga tgccagtgtg cgtctggctg tcaatgcaga tgtcctagtt catgagtcca
    48121 cttatggcaa gggtgatgaa aaaattgctc gtaaccatgg tcactcaact aatatgcaag
    48181 ctgcacaagt agcggtagaa gcaggtgcca aacgcctcct actcaaccat atcagtgccc
    48241 gtttcctctc aaaagatata agcaaactca agaaggacgc tgccacaatt tttgaaaatg
    48301 tccatgtggt caaagacttg gaagaagtgg aaatctagca gtcacagaaa ggataagtat
    48361 gcctactatt ctcattaccg gagctagcgg tggtctagct caagaaatgg tcaaactctt
    48421 gcccaatgac caactcatct tgcttggtag aaataaggaa aaattagccc aactctacgg
    48481 aaattattcc catgcagaat tgattgaaat tgatattacc gacgattcag ccctagaagc
    48541 tctggtaact gatctttatc tccgctatgg caagattgat gtcttgatta acaacgctgg
    48601 ttacgggatt tttgagggat ttgaccagat tgctgataaa gatattcacc agatgtttga
    48661 ggtcaatacc tttgccctga tgaatctgtc tcgtcacctt gcggctcgta tgaaggaaag
    48721 cagcaaaggg catatcatca acatcgtcag catggcaggt ctaatagcta ctggcaagtc
    48781 tagtctttac tcagcgacca agtttgcggc tattggtttt tcaaatgctc tgcgactcga
    48841 acttatgccc tatggagtct atgtgacaac agtcaatcca ggtccaatcc gaacaggatt
    48901 ttttgaccaa gctgacccag atggaactta tcttaaatcg gttgaccgct tcctcttaga
    48961 ggcagatgca gtggctaaaa agattgtcaa gattataggc aaaaataaac gagaactcaa
    49021 tctcccgatt ttgttgaacc tagcccataa gttttatact ctctttccca agctagctga
    49081 taagttggca ggggaaactt ttaattataa gtaaaaagaa ccaatgtgca ggttgttgct
    49141 agcctacata ttggttctta tcatttctca actatcaaac tgaacttctt ctagtagata
    49201 gtcgataaag cgttcgccca tcttagatag gctggttttc tcatgctgga tatagaccag
    49261 ctcaatcggg tcatcaatat ccagtgggat agaaacgata ttgtctccgt ttaggttgct
    49321 gttcaaaatc cctgtcgcaa tggtataacc atccaaacca atcaagagat taaagagggt
    49381 ggcacggtca ctgaccacaa tggatttctt gtggtgttcc tgagaaagaa tctcttctga
    49441 aaagtagaag gagttgtgcg tcccttggtc atagctgagg taagggaaat tctccaaatc
    49501 agacagtttc accttgtctt tctttgccag agggttggtc ttgctgacaa agatatgcgg
    49561 ttgcgctgtg aagagatggt gggctagcag gtgattgtca tccagcatct tggttaaaac
    49621 atcacggttg taactgttta agaagaggac cccgacctca ctgcggaagt tcttgacgtc
    49681 gtcgataatc tcccaagtcc gagtttcacg aaggaagagt tcgtatttct ccatatcgct
    49741 tttcttgagc aaagagacaa aggcattgac cacaaaggca tagtgttgag acgaaacgct
    49801 aaagagttcg cggtgggcga caggattttt atagcgttcc tccagaagct gggtctgctc
    49861 gacaacctga cgggcataag agagaaactc catcccatca cgggtcaagg tgattccctt
    49921 gggattgcgg ataaagatct caatgcccat ttcattttcc aaatctcgca ctgcattgga
    49981 gagacttggc tgagtgataa agagttgctt ggctgcctca ttcatggagc cagtttcgac
    50041 gattttgata atataatgta attgttgaat tctcatgttt ttattgtacc atacttgcct
    50101 tagaatcgct aaagaagata ggaaaataag gagcattgta tgagtctctt cttgaaaaaa
    50161 acacaaaatt ttgctagaat gagtcttatg aaaacattct atgatgtgca gcaattcctc
    50221 aaacgatttg gtattattgt ttacatggga aaacgcttat atgatattga actgatgaag
    50281 ttggaactat ctcggattta cgatgcaggg ttgatggata aattagacta tctagaggca
    50341 gaagcagttc ttcgcagaga gcacaaggta gaattggatt atattgagaa aaatggagaa
    50401 aagaactaat ggttacttgg attttgtggg cacttatact agcaatgttg gcgtggatgg
    50461 gctttaacta tcttcgtatt cgccgtgcgg ctaaaattgt ggacaataag gagtttgaag
    50521 ccttgattcg tacgggtcaa ttgattgatt tgcgcgaccc agcagaattc cacagaaaac
    50581 atatccttgg tgcacgcaat attccttcaa gtcagttgaa aactagtctt gcagcacttc
    50641 gtaaagataa acctgtcctt ctctacgaaa accaacgtgc gcaacgagtt acaaatgcag
    50701 ctctttactt gaaaaaacaa ggtttttctg agatttatat cctttcttat ggcttggatt
    50761 cttggaaagg gaaagtgaag actagctaac cttatttcca aattagtcga atgataggat
    50821 gaagctattg ttttatagta taattaattt gtataaaatt taaagagttc ttagaacatg
    50881 aaagaaaaga agaaaaatcc actttttgtg ggtatcttgt cgattattct tggtttgtta
    50941 tttccaattg taggcctgat tttgggtatc ataggattgg tcttggctat ttcataccaa
    51001 aaagagtcac aattagacta taaaatagaa aagattctta atatcttagg aattgtgatt
    51061 tctgtagtta actggattgt agcaatcgcc ttaatttttc ggtaaataaa agaaaaaagc
    51121 tttagtttta aagctttttt tattttatcg actcatctct aaatagtttt taatgatttg
    51181 taactctttt tggttcaaag ggcggtagtt accttctgct aaatctgggt tcaatgtgaa
    51241 gtccccaaat tggattcttt tgaggctagt caccttaaca ccaaccgaga ggaacatttt
    51301 cttgatttga tgaaattttc cttctgaaat ggtgatagag gcttgactga gggagggact
    51361 tgctgataga atctctagtc ttgcaggttt acagatagtg ccatctaaaa agacaattcc
    51421 cttttgaaag gcttggatat ggtcaggtgt tagaagtcca ttaacctcaa cttgataagt
    51481 cttatcgaca tgatattggg gatggaggag ttggaagccc aagggaccgt tatcggtcaa
    51541 gagaaggagt cctgttgtat ctcggtccag tcggccgacg gcatagagct tgtcagactg
    51601 aatgtcagat ggaagcaggt ccatgacggt cggaagttcc ttgtctttgt tggctgtaac
    51661 gacaccagca ggtttatgaa gcataagata ggtgtgttca tagccttgaa tgattcgatc
    51721 ctgaaaaagg agttcttgta gtcctgtatc gatattttgg gctagggagc gggctgggca
    51781 actatcgacg agaatgtccc ctttgagtaa ggcttgtttc atggcctttc ggctgatttt
    51841 ttcttgagct aataaattat ctaaacgcat actgtgccta tcttatcata agtcgcttgc
    51901 tttgaaaagg cttgacgtga aaagaaaagc ggagtgaaaa catttacact tgcttgagtt
    51961 atgttattta tttgaaatta tggtataatc gttcagttag aaaataaatt ttgaatatta
    52021 tagaggaaat catgacaaaa ttaagagaag atatccgtaa cattgcgatt atcgcccacg
    52081 ttgaccacgg taaaacaacc ctggttgacg aattattgaa acaatcagaa acgcttgatg
    52141 cacgtactga attggcagag cgtgctatgg actcaaacga tatcgaaaaa gagcgtggga
    52201 ttaccatcct tgctaaaaat actgccgttg cttacaacgg aactcgtatc aacattatgg
    52261 acacaccagg acacgcggac tttggtggag aagttgagcg tatcatgaaa atggttgacg
    52321 gtgttgtctt ggtcgtagat gcctatgaag gaaccatgcc acaaactcgt ttcgtattga
    52381 aaaaagcctt ggaacaagac cttgtcccaa tcgtggttgt taacaaaatc gataagccat
    52441 cagctcgtcc agcagaagta gtggatgaag tcttggaact tttcatcgag cttggtgcag
    52501 atgacgacca gcttgatttc ccagtggttt atgcttcagc gatcaacgga acttcttcat
    52561 tgtcagatga tccagctgac caagaagcga ctatggcacc aatctttgac acgattatcg
    52621 accatatccc agctccagta gataactcag atgagccttt gcagttccaa gtgtcacttt
    52681 tggactacaa tgacttcgtt ggacgtatcg gtatcggtcg tgtcttccgt ggtacagtta
    52741 aggttgggga ccaagttacc ctttctaaac ttgacggtac aactaaaaac ttccgtgtta
    52801 caaaactctt cggtttcttt ggtttggaac gtcgtgaaat ccaagaagcc aaagcgggtg
    52861 acttgattgc cgtttcaggt atggaagaca tctttgtcgg tgaaaccatc actccgacag
    52921 atgcagtaga agctcttcca atcctacaca tcgatgagcc aactcttcaa atgactttct
    52981 tggtcaacaa ctcaccattt gctggtaaag aaggtaaatg ggtaacttct cgtaaggtgg
    53041 aagaacgctt gcaggcagaa ttgcaaacag acgtttccct tcgtgttgac ccaactgatt
    53101 caccagataa atggactgtt tcaggacgtg gagaattgca cttgtcaatc cttatcgaaa
    53161 caatgcgtcg tgagggctat gaacttcaag tatctcgtcc agaagttatc gtaaaagaaa
    53221 tcgacggtgt taaatgtgaa ccatttgaac gtgtacaaat cgacactcca gaagaatacc
    53281 aagggtctgt tatccaaagc ctttctgaac gtaaaggtga aatgttggat atgatttcaa
    53341 ctggtaatgg tcaaactcgt ttggtcttcc ttgttccagc gcgtggtttg attggatact
    53401 caactgagtt cttgtcaatg actcgtggtt acggtatcat gaaccatacc ttcgaccagt
    53461 acttgccatt gattccaggg gaaattggtg gacgtcaccg tggtgccctt gtttctatcg
    53521 atgctggtaa ggctacaact tactcaatca tgtctatcga agaacgtggt acgatctttg
    53581 tcaacccagg tactgaggtt tatgaaggaa tgatcatcgg tgaaaactct cgtgaaaatg
    53641 acttgacagt taacatcacg aaggcaaaac aaatgaccaa cgttcgttca gctactaagg
    53701 accaaacagc tgttatcaag acgcctcgta tcttgacact tgaagagtct cttgagttct
    53761 tgaacgacga tgagtacatg gaagtaacgc ctgagtctat ccgtttgcgt aaacaaatcc
    53821 ttaacaaagc agagcgtgag aaagctaaca agaagaaaaa atcagctgaa taagagctag
    53881 aaagagagaa agatggtcta tttagtccta ggaattttac tgctcctact ctatgtattt
    53941 gcgacaccag aaagcattaa agggacagtc aatatcgtcg ctatggtatg tattttagtg
    54001 gcactcttga ttttattggt tctatctttt ctgaaaattt ttcaattacc aacagaaata
    54061 ttcctagcaa tagccatgtt gatcctagct tactttagtg tgagagacat cacactcatg
    54121 ccagtcaaaa aaagtaaaag aagataaaaa agagagtttc ggctctcttt tttgctagga
    54181 attttacaag attgcaattt atttttgagt tatcaccatc tcttttgttt ggataatatg
    54241 aatgggaaaa acttgaataa aattctttaa tggcatctat tttatatttg gttagtactg
    54301 gttgcatatt attttgaaat aaaactacta tataatatta ttcatagagg taatatagta
    54361 aaatatctaa aaaattcgat tttttccttg acaacaaata ataaaaatgt tatcctcatc
    54421 acataagaaa gcggtttcaa caaaagaaag aggagggttt attttgttgc attgttgctc
    54481 aaggtgtgct ttttttgaaa gaaaaaataa aatgaaaacg aaaaaacata gattacttgc
    54541 tctagttctt atttcaagtt ttacattatt gggagctgca tcagctgctg tacaatatcc
    54601 agatggagga gtatggacat atggagaagg ttcaggaggt ggttgggctt tttcaaatta
    54661 ctatcatggt aaaaaatatc attattcatc catcgtgagc agatgggatg gtcattctga
    54721 taaaggagaa gctcctgctg gaaaaacctc ctatgcatgg atttggacta aatggggaga
    54781 acaagtagca ttttactgtg attatgacta atcgttcatt gatttaaatc gttccccttg
    54841 taagaaatta cagggggaat tttgtttaca aggagtctac tatgaagaaa ctattcatat
    54901 tattatcaac tttttttctc agcttcttcc ttgcttggat tattgtctta cgtgcgccac
    54961 aatatttata tgcaagctat gattccgttt ctttacttcg tgtcaaaaaa gatactcagg
    55021 aaccgacgcg tgaggtattt gaacaggaat tggagaattt tgcaaactca gaacagagtt
    55081 taatagctag aagaattgta gagccgagta aggatgggac gactcacttt acttatgcaa
    55141 cttatggtca gggaacttta ccaaaagaat tccaagaagc tagccaagaa agtcgtgaac
    55201 gtagtgatcc gctaaatagt tatctccttt tgtcaggctc cttgacgaaa gaaaagcttg
    55261 ccgataaatt aggagatttg ggttataaag caagtgctga ccgaaagata ccgccctatt
    55321 ttcttgcttt tcgaatatta ctaaatcccc ttattttaat tagtttagca atatttggct
    55381 tatctttctt tgctttagtg attatcactc ggattaagga aatgagagca gcaggtataa
    55441 aactcttttc tggtcagact ctcttatcca tcatggggca ttctttatct actgatatca
    55501 aatggctcct tctatcagcc ctcctttcct tcctaggtgg gggagtcgtt ctttttagtc
    55561 aaggtttgtt ttatcctatc ttgttagcca cctatggttt tgggattagt ttctatctgt
    55621 tgtttttatt ggcgatttca attttactaa tgctccttta cctaatgagt ttgagttaca
    55681 aagcattagt tcctgttatt aaggggagat taccccttaa acgcttgatg gctttaaccc
    55741 tattgtgtca gttggttgct gtctttacag taggctacgc tgttaagaca ggtttgatgt
    55801 cttaccaacg attgaaagaa cttgaaattt caaaacaagc atggcaggat agagcagact
    55861 attatcaaat ttcttttggc ttaggtgata gaggaaaaga tacagaaaat cagagcaagt
    55921 ggtatgcctt tgccaaggaa gcaatcgaag aagaacaagc tctttatgta aaggataatc
    55981 tgctccattt tgccaatcca caaggaaaaa atgaacaggg agagacactg gatacctata
    56041 gtccagatgc taatacgctc tatgttagtc ccagttattt ggacaaggaa aaggtcgtgg
    56101 tagatgctga gaccaaacag aagttagccc atctccaaaa aggtgagttt atcctcttgc
    56161 tcccagaaca tttgcgctct cgagaagcag aacttaagaa agtttttgaa gaaagattga
    56221 gttattatgg aaaatctggt gaggaggcaa gtgctccttt ggattatgag atgaaagcgc
    56281 acgttagtta tctttcaatg ggagaaaagc ggtttgttta taataacggt gagaatcccg
    56341 tatccactca gtatttgatt gatccgattt tagttgtatt cacgccgact tctacaggtg
    56401 atagttttat atccttatct agttggtcta tcaatgctgg aaaacaactc tttatcaaag
    56461 gatatgagag tgggctagaa ctcttgaaga aagctggaat ttatgagcaa gtatcctatc
    56521 ttaaagaagg aagaagtgtt tatctaactc gttataatga agttcaaact gaaacagcaa
    56581 ctttaatctt aggagctatt gtggggatag ctagttcctt gttactcttt tattctgtca
    56641 atcttctata tttcgagcaa ttccgccgag atatcttgat taaacgaatt tcaggtttac
    56701 gattttttga aacacatgct cagtatatgg ttagtcaatt tgccagtttt gtatttggtg
    56761 ctagtctctt tattttaagc agtcgagact tggtgattgg cttgctcact ttattagtct
    56821 ttctagctag tgcagttctg acgctttacc gtcaagcgca gaaagaatct cgtgtttcta
    56881 tgacaattat gaaaggaaaa taggatgatt gaactaaaga atatatctaa aaaatttgga
    56941 agccgtcagc tattttcaga tacgaatctt cattttgaag gtgggaaaat ttatgcctta
    57001 atcggtacaa gtggctgtgg taagacaaca ctcttgaata tgattggacg attagagcca
    57061 tatgacaaag ggcaaatcat ctatgatggc acttctctta aggacatcaa gccttctgtt
    57121 ttctttagag attacttagg atacttattt caagattttg gcttaattga aagccaaacc
    57181 gtcaaagaga atctcaatct gggtttagtt ggtaaaaagt tgaaggaaaa agagaaaatc
    57241 tctttgatga aacaagctct aaaccgtgta aacctctctt atttggattt gaagcaacct
    57301 atatttgagt tatcaggagg agaagcacaa cgtgttgcac tagcgaagat aattttaaag
    57361 gatccacctt tgatcctcgc agatgaacca accgcttcct tagaccccaa aaactctgag
    57421 gaattacttt ccatcctaga atctttaaaa aatccgaatc gaactattat tattgcgacc
    57481 cacaatcctc ttatttggga acaagtggac caagttattc gagttaccga tttatcacat
    57541 agatgataag gcaagattca gttagaagaa agagtcacaa acacactttg tggctttttt
    57601 atttccataa aaatggtaaa atagtaggag tagaaatgga gttcgagaca tgaaagtaat
    57661 agatcaattt aaaaataaga aagtccttgt tttaggtttg gccaagtctg gtgaatctgc
    57721 agctcgtttg ttggacaagc taggtgccat tgtgacagta aatgatggga aacctttcga
    57781 ggacaatcca gctgcccaaa gtttgctgga agaagggatc aaggtcatta caggtggcca
    57841 tcctttggaa ctcttggatg aagagtttgc tcttatggtg aaaaatccag gtatccccta
    57901 caacaatccc atgattgaaa aggctttggc caagggaatt ccagtcttga ctgaggtgga
    57961 attggcttat ttgatttcag aagcaccgat tattggtatc acaggatcga acggtaagac
    58021 aaccacaacg actatgattg gggaagtttt gactgctgct gggcaacatg gtcttttatc
    58081 agggaatatc ggctatccag ctagtcaagt ggcccaaact gcgtcggaca aggacacgct
    58141 tgttatggaa ctttcttctt tccaactcat gggtgttcaa gaatttcatc cagagattgc
    58201 ggttattacc aaccttatgc caactcatat cgactaccat gggtcatttt cggaatatgt
    58261 agcagccaag tggaatatcc agaacaagat gacagcagct gatttccttg tcttgaactt
    58321 taatcaagac ttgacttcca agacagaagc cactgttgta ccattttcaa cacttgaaaa
    58381 ggttgatgga gcttatctgg aagatggtca actctacttc cgtggtgaag tagtcatggc
    58441 agcgaatgaa atcggtgttc caggtagcca caatgtggaa aatgcccttg cgactattgc
    58501 tgtagccaag cttcgtggtg tggacaatca aaccatcaag gaaactcttt cagccttcgg
    58561 tggtgtcaaa caccgtctcc agtttgtgga tgacatcaag ggtgttaaat tctataacga
    58621 cagtaaatca actaatatct tggctactca aaaagccttg tcaggatttg acaacagcaa
    58681 ggtcgtcttg attgcaggtg gtttggaccg tggcaatgag tttgacgaat tggtgccaga
    58741 cattactgga ctcaagaaga tggtcatcct gggtcaatct gcagaacgtg tcaaacgggc
    58801 agcagacaag gctggtgtcg cttatgtgga ggcgacagat attgcagatg cgacccgcaa
    58861 ggcctatgag cttgcgactc aaggagatgt ggttcttctt agtcctgcca atgccagctg
    58921 ggatatgtat gctaactttg aagtacgtgg cgacctcttt atcgacacag tagcggagtt
    58981 aaaagaataa tatgaaaaaa attgtcttta caggtggggg gacggttgga cacgttaccc
    59041 tcaatctttt gttaatgccc aagttcatcg aagatggttg ggaagtccac tatatcgggg
    59101 acaagcgtgg tatcgaacac caagaaatcc ttaagtcagg tttggatgtc accttccatt
    59161 ctattgcgac tggaaaactg cgtcgctatt tctcttggca aaatatgctg gacgtcttca
    59221 aagtttgctg gggaatcgtc caatcgctct ttatcatgtt gcgacttcgt ccacagaccc
    59281 ttttttcaaa ggggggcttt gtctcagtac cgcctgttat cgctgcgcgt gtgtcaggag
    59341 tgcctgtctt tattcacgaa tctgacctgt ctatgggctt ggccaataaa atcgcctata
    59401 aatttgcgac taagatgtat tcaacctttg agcaagcttc gagtttgtct aaggttgagc
    59461 atgtgggagc agtgaccaag gtttcagatc aaaaaaatcc agaaccagat gaattggtgg
    59521 atattcaaag ccactttaat cataaattgc cgactgtatt gtttgttggc ggttctgcag
    59581 gtgctcgtgt ctttaaccaa ttggtgacag accataagaa agaactaaca gagcgctaca
    59641 atattatcaa tctaactgga gattctagcc tgaatgagtt gagccaaaat ctttttcgtg
    59701 ttgactatgt gaccgatctc tatcaaccct tgatggaatt ggctgatatt gttgtgacac
    59761 gaggtggtgc caatacgatt tttgagctct tggcgatagc aaaattgcat gtcattgtgc
    59821 cgcttggtcg tgaagctagt cgtggtgacc agcttgaaaa tgcagcttac tttgtaaaaa
    59881 aaggctatgc agaagacctt caagaaagcg atttgacctt ggatagtttg gaagagaagc
    59941 tttctcactt actaagtcac aaggaagatt accaagctaa gatgaaggct tctaaggaat
    60001 tgaaatctct agcagatttt tatcaattgt tgaaaaaaga tttatcataa ggaaagtaaa
    60061 tgtcaaaaga taagaaaaat gaggacaaag aaatcctcga agaattgaaa gagttatcag
    60121 aatggcagaa acgaaaccaa gaatatctaa aaaagaaggc tgaagaagag gcggctctag
    60181 ctgaggagaa ggaaaaggaa agacaagctc gaatgggaga agaatctgag aagtcagagg
    60241 acaaacagga ccaggagagt gaaacagacc aggaagattc agaatcagct aaggaagagt
    60301 ctgaagaaaa agtagcatcc tcagaggctg acaaagagaa agaagagaaa gaagaaccag
    60361 agtctaaaga gaaggaggaa caggataaaa agctttctaa aaaggctaca aaggaaaaac
    60421 cagccaaagc aaagattcct ggtatccata tcttgcgagc cttcacgatt ttatttccaa
    60481 gtctgctttt attgattgtc tctgcctact tgctcagtcc ttatgcgacc atgaaagata
    60541 ttcgtattga gggaacggtg caaactacag ctgatgatat tcgacaggct tcaggcattc
    60601 aggattcgga ttatacgatt aaccttctgc tagacaaggc aaaatatgaa aagcagatta
    60661 agtctaacta ttgggttgaa tcagctcaac ttgtctatca atttccaact aagttcacta
    60721 ttaaggtcaa ggaatatgat attgtggcct actatatttc tggtgaaaat cattatccta
    60781 ttctttccag tggtcagctt gagactagtt ctgtgagtct gaacagttta ccagaaactt
    60841 atttatcagt tctctttaat gatagtgaac aaatcaaggt ttttgtctca gaacttgctc
    60901 aaattagccc agaactcaag gcggctatcc aaaaggtgga attagcccca agcaaggtga
    60961 catccgattt aattcgattg accatgaatg attcggacga agtcttggtt cctctatctg
    61021 aaatgagtaa gaaactgcca tattacagta agattaagcc acaattgtca gaaccgagtg
    61081 tggtcgacat ggaagctgga atttacagtt acactgtggc ggataaatta attatggaag
    61141 ctgaggaaaa agccaaacaa gaggccaagg aagccgagaa aaaacaggaa gaagaacaga
    61201 aaaaacaaga ggaagagagc aatcgaaatc aaacaaatca gcgttcatcg cgtcgctagg
    61261 tttacctttt ctcttatagt tctttagtga ccatgttttt acttgacaag tgctagtaga
    61321 aataatagaa tagtaaaaaa cctttaaagc agtccagaga ggcagctaag gttagacggt
    61381 gaaagggtgg agactaccca tttttcgtgg aaccttgctg ttggcaggtt ccttttttcg
    61441 tggcttctgt tggccagact ctctcactag taaaggcaaa aggagaaacc tatgcgagaa
    61501 catcgtccaa tcattgctct tgattttcct aattttgagg cggtcaagga atttttagct
    61561 cttttcccag cagaagaaag cctttatctc aaggtaggga tggagcttta ttacgcagcg
    61621 gggcctgaga ttgtgtccta cttaaaaggt ttgggtcata gtgtcttttt ggatctcaaa
    61681 cttcatgaca ttcctaatac agtcaagtca gccatgaagg tcttgtctca gcttggtgtc
    61741 gatatgacta atgtccatgc ggctggtggt gtagagatga tgaaggcggc gcgtgaaggt
    61801 cttgggagtc aagccaaatt gatcgctgta actcagctga catcaacgtc agaagctcag
    61861 atgcaggagt ttcaaaatat ccaaaccagt ctgcaagagt ctgtgattca ctatgccaag
    61921 aagacagctg aagctggctt ggatggtgtt gtttgctcgg ctcaggaagt acaagtcatc
    61981 aagcaggcta ccaatccaga ttttatctgt ctgacaccag ggattcgtcc agctggtgtt
    62041 gcagttggag atcaaaaacg agtcatgaca cctgctgatg cctatcaaat cggcagtgac
    62101 tatatcgtag tgggacgtcc cattacccaa gctgaggatc ctgttgcagc ttatcatgcc
    62161 atcaaggatg aatggacaca ggactggaat taaagaacta gattagaaaa ataaaaggag
    62221 aataccatga cacttgctaa agatatcgct agccacctct tgaaaatcca agccgtttac
    62281 ctcaaaccag aggaaccctt cacttgggca tctggtatca agtcaccgat ttacactgat
    62341 aatcgtgtga cactagccta tccagaaact cgtaccctaa ttgaaaatgg ttttgtggaa
    62401 gctatcaaag aagcctttcc tgaagtagaa gtgattgcag gaactgcaac agcagggatt
    62461 ccacacggag ccattattgc tgataagatg gacttgcctt ttgcctacat ccgtagcaaa
    62521 ccaaaagacc acggagctgg taatcaaatc gaaggtcgcg tagctcaagg tcaaaaaatg
    62581 gtagtggttg aagaccttat ttcaacgggt ggttcagttc ttgaagctgt agcagcagcc
    62641 aagcgagaag gagcagatgt acttggagtt gtagcgattt tcagctacca attgccaaaa
    62701 gcagataaga actttgcaga tgctggtgtt aaacttgtga cgctttcaaa ctatagcgag
    62761 cttatccatc tagcccaaga agaaggttac atcacgccag agggccttga tcttctaaaa
    62821 cgctttaaag aagaccaaga aaattggcaa gaaggttagg tcagtaagat aaagagagac
    62881 gaggctaccg agtctctttt accattttat ttaaaatatg acaatatttt aaataaaata
    62941 attgacaacg ctttctttta ttgatataat gaaaatgtaa tatgtatcaa attgatcaat
    63001 caactatctt gtttatcact tcttaagagg acgatgtcat gaaaagaaga aaaatatatt
    63061 ccttttttgc gtagttacaa ttgcatctag tttgtttctc cctacagttt tagctagaca
    63121 gattggaaat tatgatttaa cgttgccgcg ttggggttcg gatacaacta gtgagcttga
    63181 gaaagaaaac gcctctgctg gaattaataa cagtgacagc actggtggcg gtaaaaggtt
    63241 aagtacctct attcgtagcg cctatagtgg gtcagatatt accccggtat attcattggg
    63301 gtctggctct aggattgtca tgtactataa tggaggtggt gacaattata ttggttctgg
    63361 tactagatta gctatggcgc cacaatttgg aaatcatgta agaattcata cttcaggttc
    63421 ttggagtcca gattcttatt aacttacttg tcagagtaag ccttaaagat ggttgattgt
    63481 gggtgtagca tgaaaaaaga atgctacacc ctatttttat tataaggagg agtaaggatg
    63541 gaatttttca tttgtaatct tgtacgagtc gttcaatcac ctcgatttta tatgtcttta
    63601 tttttgaccc ttctttgcat gagtttagga aatttccttg ctttcaatgg tatttataaa
    63661 attgaaggtt tatcgatttt ttttgccgct tcttctattc gaggattttc accgattagc
    63721 ctagtagctg cacttatctg tacactgccc tattctagtc agataataga ggatgctgag
    63781 agtcattttc taacagcaca attgtgccga atttctaaaa agaagtatct ggctattgta
    63841 ggtagtactg caattatttc ttcttttcta gtcttttttc tcccctattt attattatta
    63901 ggaattaatc ttttagtgac tccttatcag gaaatttata ttggagatta tagtggtgcc
    63961 ttaaaagaat tatttgattc taatcagttg ctctatagtc ttgtgacgac tctctggtat
    64021 ggagtttggg gcgctgtgtt ctctattttt ggactagcta gtgctttgct agtgaagaaa
    64081 aaaataggag ctattttcat cccagttgcc tatatgatgg ttggtggtat tttttgggct
    64141 attttagggc tatcttactt agaacctgtg acaacattag ctttgggata tcagaaagat
    64201 atcagtcttt ccttagttag tgggcatctt gcttttattt tatttgttag ttgtttggtt
    64261 gtttatggta cattttttct acattcagag gactatgtat aatgaaacaa tttgttcaat
    64321 tttacaaaaa agatttttta tcagtattgg tttattttat attactgcta tcctgtgttt
    64381 tatctagtac agtatattta ttgcgctgtc gccaatattc aatccatcca aatgtattag
    64441 aatggatctt agttttactt caagatatga cgactggagt atattgcttt ccgttcacat
    64501 atatattatt ctttttttat ttgatgaata actattttaa taggttggag tgtcgtattc
    64561 gtctgaaatc aattaagcac tttaccagtt ttagtttcaa attagcagct cttagtacgg
    64621 ggatttggac ggcgacttta tttttattga tttttctgat tgcatttagt aatggtttta
    64681 gcttctcttt ggagataaag gaggttgatt ttttaagaga attttatggt ataagtattg
    64741 caaacaatgc tagtttcttt ataggatttt ttttctctta tatagcatac tatttctttt
    64801 tatccttact tactattagc agtttttctt ggtttaaaaa atcaaacatg agcttagtat
    64861 ttctgtttac ttttttattt gtagaatcct tattctggat ttatcagttg gacaatggga
    64921 taattggatt attgccaatt tttcagtata tggtaaattc caatccgtat gcattgattt
    64981 attggcttac attactatct atcataattc cattgactgt attttctgtt catagaaact
    65041 ggaggagagt gtaaaagttg gaaatgggaa agttaagtag tcacatgtgg aggttgaatc
    65101 agataatcta taccaagtac ttttggggtt atgttctttt ttggatattg atttgtttag
    65161 gattatggta ttggttagaa ggaaatgata gacttgttat agaaatttta aaagggccta
    65221 atctgagtca aaactctttt ttagtcttat ctatatggtt gcttcattgg tttattattc
    65281 atacattttt tctagcaatt gtatatcgta gaagagcatc cgatttcttt atggaagtga
    65341 ttcgattttc ttctattaag ctctggatta ggtatcagat ttggacctgt tttctttatg
    65401 gactcatttt aatcatggta aaagttctag tgattcaatt tatgttacag ttaccaaact
    65461 gggatatagg agttttgttt atagttgatt ctttgaatgc ttgtgtgtta gtcttgtttt
    65521 gctttatgtt atacgcacta ggagcgaatg agcaaatgaa cttttcttgt gttagcttct
    65581 ttttactcat gattgtgttt ggtggtctat ttgtaggaaa tcgaactaat tatctatttt
    65641 atattttaaa tcgagggaat ggagatatag gacgagattt atttcttcag ttgctatttt
    65701 tagtctttct ttttaaaagc attttctatt tcactcgtca aaagaggagg tttatagaat
    65761 gaatgaaata attacattaa aaaatattca gttggaatta aaaaaaacat gtgtttttca
    65821 aaaccttaac tttagttgta aacaggggga aattatagga attactggtg cgaatggctc
    65881 agggaaaagt gtattgttta aattaatagc tggtttatat agtccgtctt atggagaagt
    65941 gttaatcaat ggggaaaata ttgttcctga gagaaaaatt ccagctaatt tgggagcttt
    66001 gattgaagaa cctggtttta taaattatta tagtggcttt aagaatttac aatatttggc
    66061 aagcatacga ggagtagttg gtaatcagga aatcaatgat acactgaaaa tagttggtct
    66121 atatgagcaa aaagaccaga aagttaaaac ttattcgcta ggtatgagga aaaagctagg
    66181 gattgctcaa gcaattatgg agaatccctc tattctttta ctagatgaac ctatgaatgc
    66241 cttggataaa tcaagtgtag aaaatatgag aacattgttt agaaagctct ctagtgaaaa
    66301 agggacaaca attttgattg ctagtcatag tgaagaggat attcgtatct tatgtgataa
    66361 agtatatgca atagaagata aagtatgtac actgtgttca gattgaacat cttagataga
    66421 ctcaggatgt tataggtgaa atcttaaaaa gggattggat cttaaaatcc agttcctttt
    66481 aagagttaat gactaatcaa cttttccacc ttcaacaacc aggtcatctg ctttagcagc
    66541 gtcaccgtag gttgggtgaa gtgttttttc ataggccttg tggaagaagt tttccttgcc
    66601 taatttttca atatctttat tgatgaagtc tagcaattct tggttgcctt tttgaactgc
    66661 tgccgcaatg gtatcgggat caccgaggga agtaattcct acttcaaatc ctttattttc
    66721 aagcgcccaa gctagaactt ccgtattgtc agttgaaaag gcatctccac gtccgtcaag
    66781 aagagcttgg taagagtcac tgtattggtc gtatttttgg agtttgattt ctggatgatt
    66841 cttttcaaaa taagtctcag cagtcgttcc ttttgtgaca attaaggttt taccttcaag
    66901 ttgtttgacg tctgtaatga gaccagtctt aggtgatacg acacccagag aaactttcat
    66961 atatggaagg gcaaaatcaa cttgtttctt acgttcgtca gttactgtaa agttagcaag
    67021 agtaatatct accttgtttg aaatcaagta ttccgcacgg ttggcagcat cgactgaaat
    67081 gtatttaacc ttgacaccaa ggtcttgagc tagttggttc cctagttcaa tatcgtagcc
    67141 ttggtaagaa ccatcattgt caacgtagcc aaacggtttt ttatctccaa acacggcgat
    67201 tcgcagttca ccgctttttt tgttttcatc gatagtgcga gctttggcag ttgtttttcc
    67261 agaggatgga ccagcgtttc cacctgagct acaagcagtg ataaagataa gggcaaaggc
    67321 aagtgctaaa acagttaaga gtggtttgaa tagtttcata agaatctcct ttatagatat
    67381 gagccgaatt ggctaaagtc aaagacgttt aaaaattcct gggctcgttt ggtttgcgga
    67441 ttggtaaaga aggcttgagc tgttccttct tcagcgattt tcccttggtc gaggaagata
    67501 atccggtcag caatggcttg ggcaaactgc atttcgtggg ttactaaaat catggtacgg
    67561 ccttcttgga ccaaatcatt gataagttcc agcacctcac gcaccatttc tggatccagc
    67621 gaagcagtca cctcgtcaaa aaggatgatt tctggatgca ttaggagggc acggacaatt
    67681 gcaacacgtt gcttctgtcc accagataat tgacgggcaa agctatgttg tttatccagc
    67741 aaaccgacac gatctagtaa ttgcaaagct tcttccgtta cttctttctt gtcccttcct
    67801 tgagttttga tagggcctag gatgaggttt tgtaagacat ccagatgggg aaagagttca
    67861 taactttgaa agaccatgcc aatcttttgg cgaactaggt gaaaatcttt tttattttca
    67921 acgatagact gaccatccag aaaaatatct ccaccttgaa tactttctaa gccgttgagg
    67981 caacgaagga gggtactttt cccacaacca gagggcccta ggatgacaac aacttccctt
    68041 ttttgatttc tagagaaagt ccttggagga tgggattgtc tccgaaggat ttttttagtt
    68101 ccttgatttc taagatagtt tcagacattt agtttctcca atgtttttct aagtgagtgg
    68161 atagtttgga aatagggtag caaactgcga aatataagac tagaatggtt ccataaatcc
    68221 aaaatgaagc agttgggatg gtcaggcgat tgctatcgat gatttgttgt ccaactttgg
    68281 tcacttccac aaccccaatc aaaacaacta atgaagtggt tttaatcatc cgagtgacaa
    68341 gattgatagc ctgcggtagc agtcttctta agacttgtgg gatgatgatg tggtagtaaa
    68401 gttgaacatt agtcaagccg agtgcctgtc cactttcaaa ctgatgttta gggagagaag
    68461 tgatagctcc acgtaccaag tctcccattt cagctgttcc ccagagggta aaaacgataa
    68521 tagctgaagt ctcacctgag atattgatat taaagtttcg agctaagcca aagtaaacga
    68581 tgaagagtag caccagctgg ggcatgatac gggtaaagtc cagatacaat cgtgttaaaa
    68641 atcgtatgat tctagaatgg gaggtcatga tgattcccat gactgttccg aacatcatgg
    68701 ataagaggac agacaggatg gatatctcaa tcgtaacgcc caatccctgt aagattctca
    68761 ggagattatt tccctgaaag agtacttgga ttcccgaatc ctgcatggcg gagcctcctt
    68821 tctatccagc taaagaccag tgagatgggt agcagcatga tcagataagc aactaccaac
    68881 atagctagcg caatgtctgt ctcatagtag agaccaatca aatccttggc gacatacatg
    68941 aggtcggcca aagccactgc tgagaaaaca gaggtttcct tgataaggaa aatgacattg
    69001 gcactaaagg aggggagtgc caccgctgtt gcttgcggaa gaaccacata gcgaaagacc
    69061 tgtagaggtg tcagaccaat agcgaggcca atctcctgct gggtttgact gatggcttcc
    69121 agcccacttc ggaaagattc tgccatatag gatcctccta aaaagacaag cccaagcgtt
    69181 gcacagactt ctgaagatag gacaatcccg attcggggaa gaccgaagta gagaaagaag
    69241 agatgaatca aaaggggcgt attacgtgac aattcaatgt aggctgtcgc tacttgcgcc
    69301 aaaacaggga ttcgataatg tcggatgata ctaacgatta aaccgagcag aaaggatccc
    69361 aaaattcccc aaactgcaat atgcaaggtc agaaagaatg ccttttgata tagtggtaga
    69421 tattgttcaa caatggacca atccaaaaat agaacctccc atctagaaat aatacagtta
    69481 ttgtagcact taaaatcttc tttggataat atctattttt tattgccgtt ataaggattt
    69541 tttaccatag acataaaatt tctgaaattt ccaaacaaaa tatttgaaaa gttttgaaaa
    69601 agagttaaga tatttttgta atatacaaag tgaacgctta cttattaagg agggcatttt
    69661 atgtcataca aaacaagcaa tgcagaaggt catgtagatt tcatcaatac ctatgatttg
    69721 gagccaatgg cgcaacaagt tattcctaaa gcagcatttg gctatatcgc tagtggggcg
    69781 gaagatactt tcacttcttt ccagtgattt tagcgtcagg ttctttttag tttttaaaga
    69841 ttatccgtga atttcttgct tatttatgat aaaatggggt atcgcaaaaa atgactcatc
    69901 gtattcaatt ttgagtaaaa ctaggaggat cccatgtcta cagaacatat ggaagaacta
    69961 aatgaccagc agatcgttcg ccgtgaaaaa atggctgcgc tccgcgaaca aggaatcgat
    70021 cctttcggaa aacgttttga acgtactgca aattcacaag aattaaaaga taaatatgcc
    70081 aacctcgata aagaacaatt acacgataaa aacgaaacag ctactatcgc aggacgcttg
    70141 gtaaccaaac gtggtaaagg aaaagttggt tttgcccacc ttcaagaccg cgaaggccag
    70201 attcagatct acgttcgtaa ggatgctgtc ggtgaagaaa actacgaaat cttcaaaaaa
    70261 gcagaccttg gtgacttcct tggtgtcgaa ggtgaagtga tgcgtacgga tatgggagaa
    70321 ctctctatca aggcaaccca catcacacac ttgtctaagg ctcttcgtcc tcttcctgag
    70381 aaattccatg gtttgacaga cgttgaaaca atttaccgta aacgttacct tgacttgatt
    70441 tctaatcgtg aaagctttga acgctttgtc actcgttcaa aaatcatctc tgaaatccgt
    70501 cgttaccttg accaaaaagg attccttgaa gtggaaacac ctgttcttca taatgaagcc
    70561 ggtggtgctg ctgcccgtcc atttatcacc caccacaatg cccaaaacat tgacatggtg
    70621 cttcgtatcg cgactgagct tcacttaaaa cgccttatcg tgggtggtat ggaacgtgtc
    70681 tatgaaattg gccgtatctt ccgtaacgaa ggaatggacg ctactcataa ccctgagttc
    70741 acttctatcg aagtttacca agcttatgca gacttccaag acatcatgga cttgactgaa
    70801 ggcattatcc aacacgctgc taaatcagtc aaaggtgatg gcccagtcaa ctaccaaggt
    70861 actgaaatca agattaacga accatttaag cgtgttcata tggtggatgc tatcagagaa
    70921 attactggtg tcgatttctg gcaagacatg actttggaag aagctaaagc tatcgctgct
    70981 gagaagaaag ttccagttga gaaacactac actgaggttg gtcacatcat caatgccttc
    71041 tttgaagagt ttgttgaaga aactttaatc caaccaacct ttgtctatgg acatccagta
    71101 gctgtatctc cactcgctaa gaaaaatcct gaagaccaac gctttactga ccgtttcgag
    71161 ctctttatca tgactaagga gtacggtaat gcctttactg agttgaacga cccaatcgac
    71221 caacttagcc gttttgaagc ccaagctaaa gctaaagaac ttggtgatga tgaagcgaca
    71281 ggcatcgact atgactacat cgaggctctt gaatacggta tgccaccaac aggtggtttg
    71341 ggaatcggta tcgaccgtct ctgcatgctc ctcactgata caacaactat ccgtgatgta
    71401 ttgctcttcc caacaatgaa ataaattctt accctctggc tcttaccaga ggattttttg
    71461 attcaaaaag agactgaatt taaggagaaa atgaagtgta gtatattgaa gttgaaatag
    71521 tacactttga tttctaagac attgttagaa attggtttaa attccctaat caatttgtgc
    71581 atgttttatt tcattttacg atagtacgct gaaactgttc aaaaagtact agaaattgac
    71641 ttggattccc caattgattt gttcagattc actataaata aaaaattaat aagtgggata
    71701 ggaagttagc gtcaactagg atagtatctt gcttaaacag tatatatggg actgatataa
    71761 gtccataggt cctattagag gatgttctgg tgtcttattc acttgttttt ttatagtatt
    71821 agtagataga atccgcaaat aaaaaagtag ttcaaatgcc tggcagcaaa aaatctcaac
    71881 gattcactta atatagacta aggtttagag tttaaggaaa gtagggctag tatattgtat
    71941 gaaaaaataa gatggttttt aagcaaaact cttgaaaatg attgaaaaaa gagttattat
    72001 agttgtgtag taaaaagcaa acgcttactt aatcaaggag ggcattttat gtcatacaaa
    72061 acaagcaatg cagaaggtca tgtagacttc atcaatacct atgatttgga gccaatggcg
    72121 caacaagtta ttcctaaagc agcatttggc tatatcgcta gtggggcgga agatactttc
    72181 actttaagag agaatatccg cgcctttaac cacaaactca tcgttcctca tacactttgc
    72241 gatgttgaaa atccaagtac agagattgaa tttgcaggtg aaaaactatc ttcaccaatc
    72301 attatggcgc ctgttgcggc tcataaattg gcaaatgaac agggggaagt ggcgactgcg
    72361 cgtggtgtgc atgagtttgg ttctctttat acaaccagct cttactctac tgttgacctt
    72421 ccagagattt ctgaagccct tcaagggacc ccccattggt tccaatttta ctttagtaag
    72481 gatgacggta tcaaccgcca catcatggac cgtgtgaagg ctgaaggtta taaagcgatt
    72541 gtcttgacgg cagatgctac tgtagggggg aatcgtgaag tggataagcg taatggtttt
    72601 gtcttcccag ttggcatgcc gattgttgaa gaatacctgc cagaaggtgc tggtaaatca
    72661 atggactttg tttacaaatc agctaaacaa cgcttgtctc cacgcgatgt agaatttatc
    72721 gctgaatact ctggtcttcc tgtgtatgtc aagggaccac aatgccgtga ggacgttgaa
    72781 cgttcgcttg ctgcaggagc ttctggtatc tgggtaacca accacggtgg tcgtcaaatc
    72841 gacggtggac cagctgcctt tgactcgctt caagaagtgg cagaagcagt tgatagacgt
    72901 gtgccgattg tctttgactc tggtgttcgt cgtggtcaac acgtctttaa agccttggct
    72961 tcaggagcag acttggtagc tattggtcgc cctgttattt atggcttggc tctcggtggt
    73021 agtgtcggtg tgcgtcaagt ctttgaacac ttgaatgcgg aattgaagac agttatgcaa
    73081 ttgtctggag ctcagaccat tgaagatgtc aaacacttta agctccgtca caatccatac
    73141 aacccaacct tcccagttga ccctcgtgac ttaaaattgt attgataaaa cagattgcct
    73201 caactgaatg tggaggtttt tcttcgtgta ttggaagaat aaattgctat cgaaaactat
    73261 agtaaaatga aataagaata ggacaaatca atcaggacag ttaaatcgat ttctaacaat
    73321 gttttagaag tagaggggta ctattctagt ttcaatctac tatatataaa gatatttttc
    73381 ggttaaatat cttgctaagg ctttcatttt ttgctatact ggttcagtaa ttaaataata
    73441 gagacatttg gggtgcttta ggctgagata atacccattg aacctgatac agttaagact
    73501 ggcgaaggga aatgtgaaca gttttttcgt atggtgaaat gaacggtcta atcttgtaag
    73561 tcaactctaa ttcttgattg taattggagt tttttgttta tataaactgg ataggcttgt
    73621 ttagttagct ctctgcaaat actctcgatg tgttttaaaa ggatcaagtg gaattacgat
    73681 tttgcttgat atttcttggt gttttattaa ttactaacaa gtaaagagag gagaagtaaa
    73741 tatggaaaca caagactatg catttcagcc aggtttgact gttggagaat tattaaaaag
    73801 cagtcagaag gattggcagg ctgcaatcaa tcatcgtttt gttaaggaac tttttgcggg
    73861 gacaattgag aataaggtct taaaggacta tctgattcaa gattatcact tctttgatgc
    73921 cttcttatcc atgctgggtg cctgcgtagc tcacgcagat aaacttgaat ccaagcttcg
    73981 ttttgccaag caactaggct ttcttgaagc agatgaagat ggttatttcc aaaaggcttt
    74041 taaagagtta aaagtagcag agaatgacta cctagaagtg actttgcacc ctgtaacaaa
    74101 agcctttcag gatctaatgt attcggcagt ggcttcatca gactatgccc atcttttggt
    74161 tatgctggtc attgcagaag gtctctattt agactggggt tctaaagatt ttgctctacc
    74221 tgaagtttat attcattcgg aatggatcaa tctccacaga ggtcctttct ttgcagagtg
    74281 ggttcaattt ctggttgacg aactcaatcg tgtcggtaaa aatcgagaag atttgacaga
    74341 acttcagcaa cgctggaatc aagcagtcgc tttagaatta gctttttttg atattggtta
    74401 cgatgtctag agaaggctca tgatatttac aaatttgatg aggtaagact cttcgaaaat
    74461 ctcttcaaac cacgtcagtt tcaccttgcc gtaggtatgg ttactgactt cgtcagttct
    74521 atccacaacc tcaaaacagt gttttgagca acctgcggtt agcctcctag tttgctcttt
    74581 gattttcatt gagtataaat cattcaacgt aaatgaaaaa aatttcttaa cgaaagatag
    74641 agataaatcg aaatcagtag atcgtataaa gtgtaaagga aggatttcaa tatgacaagt
    74701 ttaaaattat taaaagaaaa agtaccattg gtcatttgta taaccaatga tgtagtaaaa
    74761 aatttcacag caaatggatt agtagcactg agcgtctcac cagccatgag tgagtttcca
    74821 gcagatttag aggatttgtt aaagtatgct ggtggtttat taataaacat aggaacattg
    74881 acagatgaaa attggaaatt ataccaagct gctctgaaaa ttgcggagaa atataatgtc
    74941 ccagcagttt tagatcctgt agcctgtgga gcaggagaat atagaaaaaa agtagcagat
    75001 gatctaatca acaattataa actagcagcg attagaggaa atgctggcga gattgcctct
    75061 ttagtaggaa tagatgtggc atctaaagga gtagatagtg cgggcgtaga taatattgac
    75121 gaaattgctc tagcagcaaa tgagaagttc aatattccaa tagtagtaac aggtgaagtg
    75181 gatgccattg ctgttaatgg agaagtggta acgattcata atggtagtgc tatgatgccg
    75241 aaagtcattg ggacaggatg cttattagga gctgtagtag caagctttat cggactagaa
    75301 aaaggtcaag aattgaaatc attagaaaca gcaatgttag tttacaatat cgctggagaa
    75361 atggcagaaa aacgtccaaa tggacatctt cctgggacat ttaaagttga atttataaat
    75421 gccttatacg agattacaga tgaagatgta aaggaattca aaagagtgaa gtaagatgtt
    75481 tcataaagaa ttactaaaac tatattttat ttgtggaacg actacttgcc aaggaaaaaa
    75541 tctatataca gtcgttgagg aagccttaaa aggtggtata accttatttc aatttcgaga
    75601 aaaaggtgag ggtgctttag aaggcttaga aaaacttgag ctagctatcc aaattaaaga
    75661 actttgtaaa aaatacaatg ttccatttat cgttaatgac gatatagatt tagcaatgga
    75721 aattgacgcc gatggcgtac atgttggtca agatgatatt ggtgttgatg aaattagaaa
    75781 attgatgcca gataaaataa ttggtctttc tataagaaac gaagaagaat ttcaacaatc
    75841 aaaagttgaa tatgtagatt atgtaggtgt tgggcctgta tttgataccc agtcaaaaga
    75901 tgatgctggt ggtgctatag gttatgaagg tcttgaattg atgagaaaac tattgccaca
    75961 aatgccttta gttgcaattg gtgggataca gacgaaacat attaaagaca ttataaagac
    76021 caatgttgac ggcgtttcaa tcatttcggc aatatcgtat gcaaaaaata tagaaaaaac
    76081 tgttcgggaa atgagtgaac aatagatatc tatccttgga ttctaagtaa gtaggatttt
    76141 ccttttttaa aaagctatgt ctagattcag cttgaatggc taattcatca aacaggtcat
    76201 ttgttttttg caaaagaaag atctgctgtc tttgtgagtg caaggctgta tttccagttc
    76261 aatttcttga actagtataa aatgtgtgtt ataataatca cataattaaa taataaagac
    76321 atttggggtg ctttaggctg agatgatacc cattgaacct gatacagtta agactggcga
    76381 agggaaatgt gaaatgtttt tttcgtatgt cgaaaagaac tgtctaatct tgtaagctga
    76441 actctaattc gtatctgtaa ttagagtttt ttcttttacg aaactggatg aagatgatat
    76501 agtagattga aataagatgc gaacaaatca attagaaaat tcaaattaat ttctagaaat
    76561 attttagcat tcttgtgtac tgttctaaat tcagtctgct atacaaagta tttaggtcgg
    76621 tcttcttgag tgccccactt ttctttaaaa aaaggagttt tttatgttga aaaaatggca
    76681 gttaaaagat gttatcttgc ttgctttctt gtctatcttt tttggtgggg ttttcgttgg
    76741 ttcaggatat gtgtataata ttctcagtct actcttaaca cctcttggtt tgcaggcctt
    76801 tgccaatgaa atcctcttcg gtctctggtg tatggctgcg cccattgctg ccatctttgt
    76861 tccgagagtc ggaagtgcaa tgattggaga agtgctagct gcgcttgctg aagtccttta
    76921 tggtagccaa tttggtctag gagctctttt gtctggcttg gttcaaggtt tgggaagtga
    76981 atttggtttt atcgtaacta agaatcgcta tgaaagttgg ctctctctaa ctgctaatag
    77041 tattgggatt acgcttgtta gctttgtcta tgaatacatt aagttaggtt actacgcctt
    77101 ttccctttcg tttgtccttt ccttgcttgt ggtacgtttt atttctgttt atttcttctg
    77161 taccatcttg gttcgtgcca ttgtcaaact ctatcatcag tttgcaactg gaggaaaagc
    77221 atagatgggt ctggaactac gagcgattca gtccccaatc ttctctgagc cgtttgattt
    77281 tacttttcat gtgcaagcct ttaccttgtt agttgggagt agtgggtctg gaaaatcaag
    77341 cctctttcaa atgattgccc aagttagttc tcttccctat agcggtcaag tcctgataga
    77401 tgggagtgag gtcagtcagc tttctatcgt cgaacgtgtc cagaaggttg gcattctctt
    77461 tcaaaatccc aatcatcaat ttaccatgga gaacttgttt gaggagttga ttttcacctt
    77521 ggagaatatc ggctatcacc ttcaggaaat tgattctaaa atagcagagg ttgtccagca
    77581 atgtcgttgc gaggcaatct tacaccgtcc cattcatcac ctatcaggtg gggaaaagca
    77641 aaaagcagcg ctggctgtcc tctttgccat gaatcctagg gtctatctct tggatgagcc
    77701 cttcgcttct attgcccgca agagcagaat cgagatattg gagattctaa aagagttggc
    77761 tcttgatggg aagacagtta ttttgtgcga ccatgattta tctgactata aagcctatat
    77821 cgaccatatg gttgagctaa gagacggaaa actaagggaa gtgtttcaaa tcccttccta
    77881 tgagatgaca caggttgctt caaaggaagt tgcttctagc ccggaactat tccatatgaa
    77941 ccgtgtgact ggtgagcttg gtaatcgccc cctcttttca attgctgatt tcacattcta
    78001 tcaagggatt tcctgtatcc tgggtgacaa tggtgtcggg aaatcaaccc tctttcggtc
    78061 tattcttcaa tttcaaaagt ataaggggcg cattgcatgg aaggggacag tcctgaaaaa
    78121 gaaaaagagt ttgtaccgtg atctgacgag tattgttcag gaagctgaga agcagtttat
    78181 ccgagtcagt ctgcgagagg agcttcaatt agatggacct gattctgaaa gaaatcagcg
    78241 gatttttcaa gctttacgat attttgattt ggagcaggca gtcgataaga gtccctatca
    78301 attaagtggt ggtcagcaaa aaattcttca gctcctgacc atcttgacca gtaaggcttc
    78361 cgtgatcttg ctagatgaac cttttgcagg tttggatgat agagcctgcc attatttttg
    78421 caagtggatt gtggaggaga ggaatcaagg aagaagtttt ctgctcatta gtcatcgttt
    78481 agaccctttg atttctgtgg ttgattattg gattgagatg actagtcagg gtcttcggca
    78541 tgtgaaagaa gtgaccatta ccaaaccact tacatctcag agtagcaata cccaagggga
    78601 ggtgagatag tatggtcaaa gtagcaaccc agacaccgat tatcagtctc ttcttgctga
    78661 ttttatcctt ggaaacatct ttcattcctt cgattgctct gaatctttcg gtagtcgcat
    78721 tttgtattct ctttatgctc tattaccgtc gatttaaaat gttagcttgg atgatcatac
    78781 ttgccatttt accatctttt gccaactact gggcagttca gttacacgga gatgcttcac
    78841 aggcagtcat gcttggaacg agggcctttg tgacagtttg tatcggcctt gtctttgttt
    78901 cctctatttc actaaaagag cttctcttgt acttggctca aaaggggcta tcacgctctt
    78961 ggtcctatgc cttgattgtg gtattcaatt cctttcctct cattcagcaa gaaatcaagt
    79021 ccctcaaaga agcttgtcta ttacgtggtc aagaactgca tttttggtcg cccttgattt
    79081 acagtaaggt tctgatgaca gtctttaggt ggcgccatct ttacctgaga gctctgtctg
    79141 ctcatggata tgacgaacat gcacagttta agaatagcta tcggactttt tatattccta
    79201 aaaaaacaaa attaatctac ctgcttttct ttttattgct tcaaaccagt ctatttttat
    79261 aaaggagtta ttatggaatt tacagatatt gcgatggaat tatccaagaa agcttggcag
    79321 gcttcctttc atcatccctt tattttacaa ttacaagagg ggaatttaga acctgccatt
    79381 ttccgctatt acctgattca ggatgcctac tatctgaagg ccttctcaga aatctatcat
    79441 cttttggctg ataagacttc aaaccaagag atgaaaagac tcttgaaaca aaatgctcag
    79501 ggtttagtgg agggtgagtt atttattcgc caacaatttt tcaaggaaat ggaaatcagc
    79561 gaccaggaaa tggagcaaca tccaattgct ccaacctgtt atcattacat ttctcatatt
    79621 tataggcaat ttgcagaacc gaacttagcc atcgcttttg caagcttgct tccttgtcct
    79681 tggttatacc atgatatagg caaatcactt aatcttaaac catcaccaaa tcctctctat
    79741 caacaatgga ttgaaactta tattacggat gagttagagc aacagatcag agaggaggga
    79801 gcactggtca atcagctcta tcgagaaagt gatgagacag ataagcaaaa aatgctagat
    79861 gccttccaca tcagtgttca tatggaagcc aagttttggg agatggctta ccaacaccag
    79921 acatggaaga gcgatttaca gtctttagaa aaaggagaag aatagaaaca tgagaaagca
    79981 ccaactacaa gttcacaaat tgaccatttt atctatgatg attgcccttg atgtagtcct
    80041 tacacctatc tttcggattg agggaatggc accgatgtcc agtgtagtca atattctagc
    80101 gggaatcatg atgggacctg tttatgcctt ggctatggct acagtgacag cctttatccg
    80161 tatgacgact caagggattc cgcctttagc tctcacagga gcgacttttg gagcccttct
    80221 agcaggtctc ttttataagt acggtcgaaa attttacttt tctgccttgg gagaaattgt
    80281 gggaacaggt attattggtt ctattgtttc ctatcctgtt atggtgctct ttacaggatc
    80341 ggctgctaag cttagttggt ttatctacac gcctcgattt ttcggagcaa ccttgattgg
    80401 tacagcgatt tcctttattg catttagatt tttaatcaag caggaattct ttaaaaaagt
    80461 gcaaggatat ttctttgctg aaaggataga atgatgcagg cattgacaaa tccttttcct
    80521 ataggctcta gttccctcat tcactgtatg accaatgaga tttcttgtga gatgctggca
    80581 aatgggattt tggctctggg atgcaaacct gtcatggcag atgatccccg tgaagttctt
    80641 gattttacta agcaaagcca ggctctcttc atcaatttgg ggcatttgtc agctgagaag
    80701 gaaaaagcaa tccgcatggc agctttgtat gcaaaccaat cttctctccc gatggtagta
    80761 gatgcggttg gcgtaacgac ttcatccatt cgtaagagct tagttaaaga ccttttagac
    80821 tatagaccta cggtccttaa aggaaacatg tcagaaattc gaagtcttgt tggattaaag
    80881 catcacggcg ttggggtcga tgcgagtgct aaagatcaag aaacggagga tttgcttcaa
    80941 gtcttgaaag actggtgtca gacctatcct ggtatgtcat tcttagtcac aggtcccaag
    81001 gaccttattg tttcggagaa tcaagttgct gtacttgaga atggctgtac tgaattagac
    81061 tggataacag ggacaggaga cttggttgga gccttaacag ctgtttttct cagccaagga
    81121 aagactggtt ttgaagcttc ttgcttagca gtctcttatc tcaatatcgc tgctgagaaa
    81181 atagttgttc aaggaatggg attggaagaa tttcgttacc aagtactcaa tcagctttcg
    81241 ctcctaagaa gagatgaaaa ttggctagat accatcaaag gagaggttta tgaatagaga
    81301 agcgcttaga ctatatctgg taaccaatcg ctatcaagat tccgtggaaa gctttcttgc
    81361 aaaagttgag acggcctgcc gttcaggggt taccatagtc caattgcgag aaaaaaatct
    81421 cacaaccaat caatattatc aactggcaaa acaagtcaag gaaataacag atgcctatca
    81481 ggtccccttg ataatcgatg atcggttgga tgtttgtctt gcggttgatg ctgctggtct
    81541 gcatattgga gatgacgaac tcccagtttc ggttgcccga caagtcttgg gtcctgaaaa
    81601 aatcctcggt gtcaccgcta aaacggttaa aagagctctg gaagcggaga aatcaggtgc
    81661 agattacttg gggacaggag ccatttttcc gacaaccacc aaggaaaatg cacccatcac
    81721 cctgatttca accttgaaaa caatttgcca aacggttgcc attccaatag ttgctattgg
    81781 cggcttgact tcggagaata ttgatcagct tatgggcact ggtatagctg gtgtagctgt
    81841 tgtacgtgat ttgatgcaag cagaagatat tgaggcaaaa acgcaagcct ttttaacaaa
    81901 gttgcatgac attctttcct aattaatact caatgaaaat caaagagtaa actagaaagc
    81961 tagtcgcagg ttgctcaaag tactgccttg aggttttaga taagactgac gaagtcagct
    82021 caaaacagtg ttttgaggtt gcagatggaa gctgacgtag tttgaagaga ttttcgaagg
    82081 gtataaaaac tctctaattc ccttaaagtg ggaactagag agtttttttc ttaatcttta
    82141 aaagttgtat ggttgactgg accagaacca tgaccgagtt gaggggcatc ttgaatagct
    82201 tttgtgataa aggccttggc cttatcaact gcctggtaaa gactcttgcc cttggctagt
    82261 tcagcagtaa tcactgcagc aaaggtacat ccagtaccat gggtgtgaca ggtttgaatt
    82321 cgtgggcttt cccagacaaa ttgttcattc ttggtaaaga ggaaatcttt agcaccacct
    82381 ttgagatgtc cgcctttgat aaccacagac tgaggaccaa attcttttaa aatcaggcga
    82441 ccagcacgct gcatgtcttc ggggtcatgg attgaaaaac caacaatctc ttctgcttca
    82501 ggaagatttg gcgtaataat agttgctaga ggtagtaagt ttgttttgag atagtctcta
    82561 gcacttgagt caatcaaggc atctccactt gtagcaacca taacaggatc aaggacatag
    82621 ggacaatcca gttttttaag atagggttgg atgatttcca tgatttcagt agtagccaac
    82681 attccagttt ttacagcctg aggtggaata tcagaaaaga cactctccaa ttgggctttc
    82741 aacatttgag gagaaacgtg ctcgattagc tgaacacctc tggtattttg agcgacaaga
    82801 ctggttacaa cagccattcc atagacatct ctcgcttgga atgactttaa atctgccata
    82861 atgccagcac caccactagg gtcagtccct gcaatggtta aagcaacggg taaataagtc
    82921 atctaaaacc tcccaaccaa ctgaagtttg tattcttaag aacaagctag tctgttttag
    82981 aaaggcaata gaagactgct agtccccatt atcatttcca cttccatcag ctagcattac
    83041 ctagattgag tcagagggat ctaacagtcg ttaatctcag ctttacgcac ccctagtggt
    83101 tgttttcttt tttctttagt atagcatatt tttattgttt atatagtaat atttgactgc
    83161 aaatcgtttt tcaaatgatt aaaattctat ttttcgaaga aaatattatt tctataattg
    83221 acaaatgtag attttgggag tatactgttg agtgtaattg acaaatgtag attttggagg
    83281 tatggtaatg cagatttcag atgcagaatg gcaggtcatg aagattattt ggatgcaggg
    83341 ggagcagacc agtacagatt tgattagggt tttggcagag cggtttgact ggtccaagtc
    83401 cacggttcag acacttttgg ctcgtctagt tgagaaagag tgtttgactc ggaaaaaaga
    83461 aggcaagtcc tttgtttatt cagcgctttt aactctagac caaagtcggg atttacttgt
    83521 ccaagatatc aaagacaagg tttgttcccg taggattagg aatttgttgg ctgacttgat
    83581 tgtagaatgt gaatttactc agactgactt ggaagacttg gaagctgtga tttcagagaa
    83641 gaaatcaagt gctgtaacag aagtaagatg taattgtatg taaaggagac gtcatgttaa
    83701 atagtattgt aaccattatt tgtattgccc ttatcgcgtt tatcttgttt tggtttttca
    83761 aaaagcctga aaaatctgga caaaaagccc agcaaaaaaa cggataccaa gagattcgag
    83821 tggaagtcat gggaggctat actcctgagt tgattgtcct caagaaatca gtgccagccc
    83881 gcattgtctt tgaccgcaag gatccttcac catgtctgga tcaaattgtt tttccagatt
    83941 ttggtgtaca tgcgaacctg ccaatggggg aagagtatgt agtggaaatc acgcctgaac
    84001 aggctggaga gtttggcttt gcttgtggta tgaacatgat gcacggcaag atgattgtag
    84061 agtaggtgga gactatgaca gaaattgtga aagcaagctt agaaaatggc attcaaaaaa
    84121 tccgtatccg agctgaaaaa ggctatcatc cagcccatat ccagcttcaa aagggaattc
    84181 cagctgagat tacctttcat cgtgctactc cttcaaactg ttataaggaa attctgtttg
    84241 aagaagaagg tatcttggaa gcaatcggcg tagatgagga gaaagtcatt cgttttacac
    84301 ctcaagaatt agggagacat gaattttctt gtggcatgaa gatgcaaaag ggaagctata
    84361 tagtcgttga gaagactcga aaatctctat ctctcctgca acgtttttgg attactagta
    84421 tctttactgt gcctcttgtg attctcatga ttgggatgtt ggcaggtagc attagtcatc
    84481 aagtcatgca ttggggaacc tttttagcaa caacgcctat tatgttagtt gcgggtaagc
    84541 catatatcca gagtgcttgg gccagtttta aaaagcacaa tgccaacatg gataccttgg
    84601 ttgcgctggg aactctagtg gcttatttct atagcctagt tgctctcttt gctggtctcc
    84661 ctgtttactt cgaaagtgct ggatttatcc tctttttcgt tcttttggga gcagtttttg
    84721 aggaaaaaat gaggaaaaat acgtcccaag ctgtggagaa attactggac ttgcaagcta
    84781 aaaccgcaga agtcttgagt gatgatagtt atgtccaagt tcctttggaa caagtcaagg
    84841 taggcgacct gattcgagtg cgtcccggtg aaaagattgc tgttgatggt gtcgtagtag
    84901 aaggtgtctc tagtattgac gaatccatgg tgacaggtga gagtctgcct gtggacaaga
    84961 cagttggaga tactgtcatt ggctcaacca tcaatcatag tggaacgctt gtctttagag
    85021 cagaaaaagt tggctcagag actgttttgg ctcagattgt agattttgtg aagaaagctc
    85081 agacaagtcg tgcgccgatt caggacttga cggataagat ttcagggatt tttgtcccag
    85141 tagttgtcat tttaggaatc atgacctttt gggtttggtt cgtcttgctc agggatagtg
    85201 tggtcgtgct tggagctagc tttgtgtcct ctcttctcta cggagtggcg gttttgatta
    85261 tcgcctgtcc ttgtgccttg ggacttgcaa caccgacagc ccttatggtg gggacaggac
    85321 gtagtgccaa gatgggggtt ctcctcaaaa atggaactgt cttacaggaa atccagaaag
    85381 ttcaaactct tgtctttgat aagaccggga ctttgacgga agggaaacct gtggtaacag
    85441 atatcatcgg cgacgaagta gaagtgtttg ggttggcagc ctccttggaa gatgcttctc
    85501 aacacccact ggctgaggct atcgttaagc gagcgagtga agctggactt gagtttcaaa
    85561 ctgttgaaaa ttttcagacc ttgcacggga aaggtgtttc agggcgaatt aatggaaaac
    85621 aagttttact tggaaatgct aaaatgctgg atggcatgga tatttctaat acttatcaag
    85681 ataaactaga agaactagaa aaagaagcta agacagttgt gttcttagct gttgacaatg
    85741 aaatcaaagg tttgcttgct ttgcaagata ttcctaagga aaatgctaag ctagtcatca
    85801 gtcagctaaa aaaacgtggt ctccgaacag tcatgctgac aggagacaat gctggtgtgg
    85861 cgcgtgctat tgcagatcaa atcggaattg aagaggtcat tgcaggcgtc ttgccagaag
    85921 aaaaagccca tgaaatccat aaactgcaac agtcaggtaa agtagccttt gttggtgatg
    85981 ggatcaatga cgctcctgcc cttagtgtag cagatgtggg gattgctatg ggagctggaa
    86041 cagatatcgc catcgagtca gcagatttgg tgttgacaac caataatctt ttaggagtgg
    86101 tgcgtgcctt tgatatgagt aagaaaacct ttcatcgaat tctactcaat cttttctggg
    86161 cttttatcta caatgttgtc ggaattccga ttgcagcagg agtcttttca ggtgttggac
    86221 tggctctcaa cccagaattg gcaggtctag ccatggcctt tagttctgta tctgttctga
    86281 ccagttccct tctgttaaat tttagtaaaa tagactaaaa gtaatgacta gatttctttg
    86341 ttataaaaca aaaatgacaa caccttcaaa actgtattag aatagagaat agagagtttt
    86401 gagcagattt ttagaaaagt cagcataaat atgatacagt ggaatagtaa aaatttggag
    86461 aacgtttcca attctatgta atcgtattct ccaagtctaa aaaaattgaa ggagagttat
    86521 cattatgact caagggaaaa ttactgcatc tgcagcaatg cttaacgtat tgaaaacatg
    86581 gggcgtagat acaatctacg gtatcccatc aggaacactc agctcattga tggacgcttt
    86641 ggctgaagac aaagatatcc gtttcttaca agttcgccac gaagagacag gtgctcttgc
    86701 agcggttatg caagctaaat tcggcggctc aatcggggtt gcagttggtt caggtggtcc
    86761 aggtgcgact cacttgatta acggtgttta cgatgcagct atggataaca ctccattcct
    86821 agcgatcctt ggatcacgtc cagttaacga attgaacatg gatgctttcc aagagcttaa
    86881 ccaaaaccca atgtacaacg gtatcgctgt ttacaacaaa cgtgtagctt acgctgagca
    86941 attgccaaaa gtaattgacg aagcctgccg tgctgcagtt tctaaaaaag gtccagctgt
    87001 tgttgaaatt ccagtaaact tcggtttcca agaaatcgat gaaaactcat actacggttc
    87061 aggttcatac gaacgctcat tcatcgctcc tgctttgaac gaagttgaaa tcgacaaagc
    87121 tgttgaaatc ttgaacaatg ctgaacgccc agttatctat gctggatttg gtggtgttaa
    87181 agctggtgaa gtgattactg aattgtcacg taaaatcaaa gcaccaatca tcacaactgg
    87241 taaaaacttt gaagctttcg aatggaacta tgaaggtttg acaggttctg cttaccgtgt
    87301 tggttggaaa ccagccaacg aagtggtctt tgaagcagac acagttcttt tccttggttc
    87361 aaacttccca tttgctgaag tttacgaagc attcaagaac actgaaaaat tcatccaagt
    87421 cgatatcgac ccttacaaac ttggtaaacg tcatgccctt gacgcttcaa tccttggtga
    87481 tgctggtcaa gcagctaaag ctatccttga caaagtaaac ccagttgaat caactccatg
    87541 gtggcgtgca aacgttaaga acaaccaaaa ctggcgtgat tacatgaaca aactcgaagg
    87601 taaaactgag ggtgaattgc aattgtatca agtttacaat gcaatcaaca aacatgctga
    87661 tcaagacgct atctactcaa tcgacgtagg taacactact caaacatcta ctcgtcacct
    87721 tcacatgaca cctaagaata tgtggcgtac atctccgctc tttgcgacaa tgggtattgc
    87781 ccttcctggt ggtatcgctg ctaagaaaga caatccagat cgccaagtat ggaacatcat
    87841 gggtgatgga gcattcaaca tgtgctaccc agacgttatc acaaacgttc aatacgacct
    87901 tccagttatc aaccttgtct tctcaaatgc tgagtacggc ttcatcaaga acaaatacga
    87961 agatacaaac aaacacttgt ttggtgtaga cttcacaaac gctgactacg ctaaaattgc
    88021 ggaagctcaa ggagctgttg gattcacagt tgaccgtatc gaagacatcg atgcagttgt
    88081 tgcagaagct gttaaattga acaaagaagg taaaactgtt gtcatcgatg ctcgcatcac
    88141 tcaacaccgt ccacttccag tagaagtact tgaattggat ccaaaacttc actcagaaga
    88201 agctatcaaa gccttcaagg aaaaatacga agcagaagaa ctcgtaccat tccgtctctt
    88261 cttggaagaa gaaggattgc aatcacgcgc aattaaataa ttcctctcgc cgaaaatcaa
    88321 atatgaaact tgtagacttt attctttgat tttcatagag cagaacttta aaagatcgga
    88381 gcaatccggt ctttttatgg aggagagtaa atgaatttaa atcaattaga tattatcgtt
    88441 tcaaatgttc cccaagtctg tgctgacttg gagcatattt tggataaaaa ggcagattat
    88501 gctgatgatg gttttgctca gtttacgatt ggtagtcact gccttatgtt gtcacaaaat
    88561 catttggttc ctttggaaaa ctttcagtca ggaatcatta ttcatatcga ggttgaggat
    88621 gtagaccaga actacaaacg gttgaacgag cttggtataa aggttttaca cggaccaact
    88681 gtaaccgatt ggggaacaga gtccttatta gttcaaggac ctgctggtct agtgcttgat
    88741 ttttatcgta tgaaataggt cgcgtagtca tttgacgtta accttagcta tttttaaaat
    88801 agaaattgag aatatgaact attgaaagat cggagcaatc cggtcttttt atataaagaa
    88861 attgcatata atactcatct gctttcaaaa agcattctag tccatctccg attaacgatg
    88921 gactttatca cctccttctc cagtccttgt atgacatctt ggagttgatt catgacctct
    88981 tccaatatgg gcatcaacag ctccataaca atagcgaaat tctcgtatat agtgactatg
    89041 gatatgtgga cctactccta ttggagccca acaagatccc agtttactga ttctaccgaa
    89101 accagcctca tcttggtaca tcaagcgaac cttacgaaaa cgtctactgg ttttaaagcg
    89161 ctttcttgtc ttcttgaatt gagattttat ttttagacgc gacaatggtt tgagcgtctg
    89221 ctttcttagg atgttctgga cgtggca
//
LOCUS       DAVKBC010000003        82365 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVKBC010000003 DAVKBC010000000
VERSION     DAVKBC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 82365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82365
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.003"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            80..1771
                     /locus_tag="VWX64_000229"
     CDS             80..1771
                     /locus_tag="VWX64_000229"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU9189789.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            complement(2161..2718)
                     /locus_tag="VWX64_000230"
                     /pseudo
     CDS             complement(2161..2718)
                     /locus_tag="VWX64_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2704..3189
                     /locus_tag="VWX64_000231"
     CDS             2704..3189
                     /locus_tag="VWX64_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU9189790.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERADLLATYPEHKEMIEHLTR
                     Y"
     gene            3273..3980
                     /locus_tag="VWX64_000232"
     CDS             3273..3980
                     /locus_tag="VWX64_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9189791.1"
                     /translation="MTKQVLLVDDEEHILRLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGIKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            3981..5312
                     /locus_tag="VWX64_000233"
     CDS             3981..5312
                     /locus_tag="VWX64_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU9189792.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAKYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            5479..6354
                     /locus_tag="VWX64_000234"
     CDS             5479..6354
                     /locus_tag="VWX64_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU9189793.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            6472..7335
                     /gene="pstC"
                     /locus_tag="VWX64_000235"
     CDS             6472..7335
                     /gene="pstC"
                     /locus_tag="VWX64_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9189794.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYSFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVIFFLILLINAY
                     FAYLKGKSSYE"
     gene            7328..8143
                     /gene="pstA"
                     /locus_tag="VWX64_000236"
     CDS             7328..8143
                     /gene="pstA"
                     /locus_tag="VWX64_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9189795.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            8145..8897
                     /gene="pstB"
                     /locus_tag="VWX64_000237"
     CDS             8145..8897
                     /gene="pstB"
                     /locus_tag="VWX64_000237"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9189796.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            8912..9562
                     /gene="phoU"
                     /locus_tag="VWX64_000238"
     CDS             8912..9562
                     /gene="phoU"
                     /locus_tag="VWX64_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9189797.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAKL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPGEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            9630..10055
                     /locus_tag="VWX64_000239"
     CDS             9630..10055
                     /locus_tag="VWX64_000239"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9189798.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEIRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(10228..10609)
                     /locus_tag="VWX64_000240"
                     /pseudo
     CDS             complement(10228..10609)
                     /locus_tag="VWX64_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            10821..11837
                     /locus_tag="VWX64_000241"
     CDS             10821..11837
                     /locus_tag="VWX64_000241"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9189799.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRSAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            11859..12758
                     /gene="galU"
                     /locus_tag="VWX64_000242"
     CDS             11859..12758
                     /gene="galU"
                     /locus_tag="VWX64_000242"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU9189800.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHAST
                     IAVMPVPHEDVSSYGVIAPQGEGSNGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(12825..13502)
                     /locus_tag="VWX64_000243"
     CDS             complement(12825..13502)
                     /locus_tag="VWX64_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU9189801.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(13486..14025)
                     /locus_tag="VWX64_000244"
     CDS             complement(13486..14025)
                     /locus_tag="VWX64_000244"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU9189802.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKRVLTPKTYPKGRMDFVVYDPQQLVKTSFGLLEPQ
                     GDLEVVDVSKIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(14037..15167)
                     /locus_tag="VWX64_000245"
     CDS             complement(14037..15167)
                     /locus_tag="VWX64_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU9189803.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEAVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(15235..15933)
                     /gene="dapD"
                     /locus_tag="VWX64_000246"
     CDS             complement(15235..15933)
                     /gene="dapD"
                     /locus_tag="VWX64_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU9189804.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(16163..17074)
                     /locus_tag="VWX64_000247"
     CDS             complement(16163..17074)
                     /locus_tag="VWX64_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU9189805.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(17139..19604)
                     /locus_tag="VWX64_000248"
     CDS             complement(17139..19604)
                     /locus_tag="VWX64_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9189806.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKAGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19746..21002
                     /locus_tag="VWX64_000249"
     CDS             19746..21002
                     /locus_tag="VWX64_000249"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU9189807.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(21080..23143)
                     /locus_tag="VWX64_000250"
     CDS             complement(21080..23143)
                     /locus_tag="VWX64_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9189808.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVIVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(23145..23423)
                     /locus_tag="VWX64_000251"
     CDS             complement(23145..23423)
                     /locus_tag="VWX64_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189809.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            23575..24423
                     /locus_tag="VWX64_000252"
     CDS             23575..24423
                     /locus_tag="VWX64_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9189810.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSKLTEITIEAEI
                     LVGKAF"
     gene            25222..25794
                     /locus_tag="VWX64_000253"
     CDS             25222..25794
                     /locus_tag="VWX64_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189811.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLVSWFVNDVALE
                     FAMNLLSSGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(26838..29096)
                     /gene="glgP"
                     /locus_tag="VWX64_000254"
     CDS             complement(26838..29096)
                     /gene="glgP"
                     /locus_tag="VWX64_000254"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU9189812.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(29122..30639)
                     /gene="malQ"
                     /locus_tag="VWX64_000255"
     CDS             complement(29122..30639)
                     /gene="malQ"
                     /locus_tag="VWX64_000255"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU9189813.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEDL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            31189..32460
                     /locus_tag="VWX64_000256"
     CDS             31189..32460
                     /locus_tag="VWX64_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9189814.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            32571..33863
                     /locus_tag="VWX64_000257"
     CDS             32571..33863
                     /locus_tag="VWX64_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9189815.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLSVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            33865..34707
                     /locus_tag="VWX64_000258"
     CDS             33865..34707
                     /locus_tag="VWX64_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9189816.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            34968..35768
                     /locus_tag="VWX64_000259"
     CDS             34968..35768
                     /locus_tag="VWX64_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU9189817.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PGQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            35778..36764
                     /locus_tag="VWX64_000260"
     CDS             35778..36764
                     /locus_tag="VWX64_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9189818.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            36900..36980
                     /locus_tag="VWX64_000261"
                     /pseudo
     CDS             36900..36980
                     /locus_tag="VWX64_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(37100..38041)
                     /locus_tag="VWX64_000262"
     CDS             complement(37100..38041)
                     /locus_tag="VWX64_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9189819.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(38019..39782)
                     /gene="aspS"
                     /locus_tag="VWX64_000263"
     CDS             complement(38019..39782)
                     /gene="aspS"
                     /locus_tag="VWX64_000263"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU9189820.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPHMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            complement(40063..40143)
                     /locus_tag="VWX64_000264"
                     /pseudo
     CDS             complement(40063..40143)
                     /locus_tag="VWX64_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(40179..40409)
                     /locus_tag="VWX64_000265"
     CDS             complement(40179..40409)
                     /locus_tag="VWX64_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189821.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(40427..41068)
                     /locus_tag="VWX64_000266"
     CDS             complement(40427..41068)
                     /locus_tag="VWX64_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9189822.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLLDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(41080..41814)
                     /locus_tag="VWX64_000267"
     CDS             complement(41080..41814)
                     /locus_tag="VWX64_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU9189823.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(41817..42014)
                     /locus_tag="VWX64_000268"
     CDS             complement(41817..42014)
                     /locus_tag="VWX64_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189824.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(42014..42220)
                     /locus_tag="VWX64_000269"
     CDS             complement(42014..42220)
                     /locus_tag="VWX64_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9189825.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(42230..42544)
                     /locus_tag="VWX64_000270"
     CDS             complement(42230..42544)
                     /locus_tag="VWX64_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189826.1"
                     /translation="MWVLVFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(42811..42888)
                     /locus_tag="VWX64_000271"
                     /pseudo
     CDS             complement(42811..42888)
                     /locus_tag="VWX64_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(42885..44174)
                     /locus_tag="VWX64_000272"
     CDS             complement(42885..44174)
                     /locus_tag="VWX64_000272"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU9189827.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVSQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(44252..45499)
                     /locus_tag="VWX64_000273"
     CDS             complement(44252..45499)
                     /locus_tag="VWX64_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU9189828.1"
                     /translation="MKLLFRNPAYRILTLSCFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(45692..46543)
                     /gene="rgg"
                     /locus_tag="VWX64_000274"
     CDS             complement(45692..46543)
                     /gene="rgg"
                     /locus_tag="VWX64_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU9189829.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSAFLSVSLFTRYVREMVRKSDFLMEMSGNRNFFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            46667..47008
                     /locus_tag="VWX64_000275"
     CDS             46667..47008
                     /locus_tag="VWX64_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9189830.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            47066..47146
                     /locus_tag="VWX64_000276"
                     /pseudo
     CDS             47066..47146
                     /locus_tag="VWX64_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(47262..48965)
                     /gene="ilvD"
                     /locus_tag="VWX64_000277"
     CDS             complement(47262..48965)
                     /gene="ilvD"
                     /locus_tag="VWX64_000277"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU9189831.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(49198..50130)
                     /locus_tag="VWX64_000278"
     CDS             complement(49198..50130)
                     /locus_tag="VWX64_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU9189832.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(50127..50984)
                     /locus_tag="VWX64_000279"
     CDS             complement(50127..50984)
                     /locus_tag="VWX64_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9189833.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(50988..52334)
                     /locus_tag="VWX64_000280"
     CDS             complement(50988..52334)
                     /locus_tag="VWX64_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9189834.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(52347..52631)
                     /locus_tag="VWX64_000281"
     CDS             complement(52347..52631)
                     /locus_tag="VWX64_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9189835.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKICEEKGLI"
     gene            complement(52635..54665)
                     /locus_tag="VWX64_000282"
     CDS             complement(52635..54665)
                     /locus_tag="VWX64_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU9189836.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKVSSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            54856..55863
                     /locus_tag="VWX64_000283"
     CDS             54856..55863
                     /locus_tag="VWX64_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9189837.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTMKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            55866..56066
                     /locus_tag="VWX64_000284"
     CDS             55866..56066
                     /locus_tag="VWX64_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9189838.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            56218..56400
                     /gene="rpmF"
                     /locus_tag="VWX64_000285"
     CDS             56218..56400
                     /gene="rpmF"
                     /locus_tag="VWX64_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU9189839.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            56416..56565
                     /gene="rpmG"
                     /locus_tag="VWX64_000286"
     CDS             56416..56565
                     /gene="rpmG"
                     /locus_tag="VWX64_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9189840.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(56987..58867)
                     /locus_tag="VWX64_000287"
     CDS             complement(56987..58867)
                     /locus_tag="VWX64_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9189841.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERMLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RHAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(58861..59730)
                     /locus_tag="VWX64_000288"
     CDS             complement(58861..59730)
                     /locus_tag="VWX64_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9189842.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHSELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(59814..62459)
                     /locus_tag="VWX64_000289"
     CDS             complement(59814..62459)
                     /locus_tag="VWX64_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU9189843.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTARYAKILLKHELTVPVSADEKLEEEQKGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGI
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLDPQEIRTEFIKKEEI"
     gene            complement(62550..63830)
                     /locus_tag="VWX64_000290"
     CDS             complement(62550..63830)
                     /locus_tag="VWX64_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU9189844.1"
                     /translation="MVYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     INSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            64002..66086
                     /locus_tag="VWX64_000291"
     CDS             64002..66086
                     /locus_tag="VWX64_000291"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU9189845.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNPLMLFTALQMNTDILAISQEGGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEEELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(66126..67805)
                     /locus_tag="VWX64_000292"
     CDS             complement(66126..67805)
                     /locus_tag="VWX64_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU9189846.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLTQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGACLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            68560..69789
                     /gene="arcA"
                     /locus_tag="VWX64_000293"
     CDS             68560..69789
                     /gene="arcA"
                     /locus_tag="VWX64_000293"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU9189847.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            69847..70863
                     /gene="argF"
                     /locus_tag="VWX64_000294"
     CDS             69847..70863
                     /gene="argF"
                     /locus_tag="VWX64_000294"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU9189848.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            71028..71975
                     /gene="arcC"
                     /locus_tag="VWX64_000295"
     CDS             71028..71975
                     /gene="arcC"
                     /locus_tag="VWX64_000295"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU9189849.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVGQLEEYIKQDQFAPGSMLPK
                     IEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            72186..73697
                     /locus_tag="VWX64_000296"
     CDS             72186..73697
                     /locus_tag="VWX64_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU9189850.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            73719..75050
                     /locus_tag="VWX64_000297"
     CDS             73719..75050
                     /locus_tag="VWX64_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU9189851.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLYGSGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(75531..75746)
                     /locus_tag="VWX64_000298"
     CDS             complement(75531..75746)
                     /locus_tag="VWX64_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189852.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGK"
     gene            complement(75734..75985)
                     /locus_tag="VWX64_000299"
     CDS             complement(75734..75985)
                     /locus_tag="VWX64_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU9189853.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(76429..77313)
                     /locus_tag="VWX64_000300"
     CDS             complement(76429..77313)
                     /locus_tag="VWX64_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9189854.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(77458..78609)
                     /locus_tag="VWX64_000301"
     CDS             complement(77458..78609)
                     /locus_tag="VWX64_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU9189855.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(78755..80521)
                     /locus_tag="VWX64_000302"
     CDS             complement(78755..80521)
                     /locus_tag="VWX64_000302"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU9189856.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTRHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(80604..>82365)
                     /locus_tag="VWX64_000303"
     CDS             complement(80604..>82365)
                     /locus_tag="VWX64_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU9189857.1"
                     /translation="QVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDK
                     TAMWALSGNFDASKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQIN
                     ISGDKNHYTYTENWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNI
                     AYAKPTTQSSVDYNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLV
                     KIYNRTDAETQRLSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLL
                     TSGVPLSLAEVEVFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDG
                     NKDGDYGHHSVTHTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSS
                     SGEEVFRRHFDKVVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKL
                     SNIALTKETRQSSTDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEEL
                     EKLIIYNRTDAEIQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRI
                     SLRNAGIPLSLAEVEVYTYK"
BASE COUNT        24757 a        17874 c        15470 g        24264 t
ORIGIN      
        1 aacaggagat ttcaaaaatt ttttcttctt tctttaaaat tgtgataaaa tagtagaaaa
       61 gtccaaaaag gagctcttaa tgaatacaaa agaattgatt gctagcgaat tggctagcat
      121 cattgatagc ctggaccaag aggctatttt aaagttactg gaaaccccta aaaactcaga
      181 aatgggtgac atcgctttcc ctgctttttc tcttgccaaa gtcgaacgta aagcaccaca
      241 aatgattgcg gctgaactgg ctgaaaaaat gaacagccaa gcctttgaaa aagttgtcgc
      301 aacaggacct tacgttaact ttttccttga taaatctgcc atttctgctc aagtattgca
      361 agctgttacc actgaaaaag aacactatgc tgaccaaaat attggtaaac aagaaaatgt
      421 tgttatcgac atgtctagtc cgaatatcgc taaaccattt tctattggcc acctgcgttc
      481 aactgttatc ggagatagct tgtcacatat tttccaaaaa atcggttatc aaacggtcaa
      541 ggtcaaccat ttgggagact ggggtaaaca atttgggatg ttgattgttg cctacaaaaa
      601 atggggcgac gaagaagctg taaaagctca tccaatcgat gaactcctta aactctatgt
      661 ccgcatcaac gctgaagctg aaaatgaccc tagcttggat gaagaagcgc gcgaatggtt
      721 ccgtaaactt gaaaatggag atgaggaagc tctcgctctt tggcaatggt tccgcgatga
      781 aagtttagtg gaatttaacc gcctttacaa tgaattgaag gttgaatttg acagctataa
      841 cggagaagcc ttctacaatg ataagatgga tgcagttgta gacattcttt ctgaaaaagg
      901 actacttctt gaatcagaag gtgcccaagt tgtcaatctt gagaaatacg gaattgaaca
      961 tccagctctc atcaagaaat ctgatggtgc aactctctat atcacacgtg acttggctgc
     1021 agccctttac cgtaaaaacg aataccaatt tgctaaatct atctatgtcg ttggtcaaga
     1081 acaatctgcc cactttaaac agctcaaagc tgtcttgcaa gagatgggct acgactggag
     1141 tgacgacatt actcacgttc cttttggttt ggttacaaaa gaagggaaga aactctctac
     1201 tcgtaaaggg aatgtcatct tgctagagcc tactgttgca gaggctgtta gccgtgccaa
     1261 ggtccaaatc gaggctaaaa atcctgaact agaaaacaaa gaccaagtag cacatgctgt
     1321 tggggttgga gccattaaat tctatgacct caaaaccgac cgtacaaatg gatacgactt
     1381 cgacctagag gctatggtat ccttcgaggg tgaaactgga ccttacgttc aatatgccta
     1441 cgctcgtatc caatctatct tacgcaaagc cgatttcaaa ccagaaacag ctggcaacta
     1501 tagcttgaat gatactgaaa gctgggaaat cattaaactc attcaagact tcccacgtat
     1561 tatcaaccgt gcggcagata actttgaacc ttctatcatt gctaaatttg caattagcct
     1621 agctcaatcc tttaacaaat actatgcaca tacacgtatc ttggatgaaa gcccagaacg
     1681 cgacagccgt ctagccctca gctacgcaac cgcagtcgtt ctcaaagaag cccttcgctt
     1741 gcttggagta gaagcgccag agaagatgta aatcgccaaa gttacttgat tgcaaagcaa
     1801 tctaagtaac taacgccaaa tcctattcgg actttggcta ggcgcttcac tagttttagg
     1861 acataaatat gatcgattta tgtcctaaaa cgtcgtaatc ttaaagttat tggaactaaa
     1921 gttcctaatt gttagacgct agccgcttat atgcgaacta gctaactgct tcactagtca
     1981 tgacccctaa atataatcga tttagaggcc atgacgtcgt aactatggta atttggctag
     2041 gcgtttcact agtaaagaaa cataaatatt atcgatttat gcttctttac gtcgtaacca
     2101 gagacacttg cctaaacgct tcactaattc acctaaccaa ataatagact tcctgcaaaa
     2161 ctagaatcct agttcatgat tgataatgcc agcaatcaaa ttcattcgta atccgaagcg
     2221 tttacgatga tttcgataag ttgttgaaaa cattttaaac gtttttactt tggcaaagat
     2281 gttctcaacc ttgcttctct ccttagatag tgcatggtta caggctttat cttcagctgt
     2341 tagcggcttg agtttgctgg atttacgtgg agtttgtgct tgaggatata tcttcataag
     2401 cccttgataa ccactgtcag ccaagatttt accagcttgt ccgatatttc tgcgactcat
     2461 tttgaacaac ttcatatcat gacaatagtt cacagtgata tccaaagaaa caattctccc
     2521 ttgacttgtg acaatcgctt gagccttcat agcgtggcat ttctttttac cagaatcatt
     2581 cgctaattct tttttagggc gattgatttt tacttccgtc gcatcaatca ttaccgtgtc
     2641 ctcagaactg agaggagttc ttgaaatcgt aaaactactt tgaacaagag ttacttcaac
     2701 ccattggctc cgacggataa agaagacttg ataagaactc tagagttagc tccccatgtt
     2761 gaaggtggct attttagaca aacaaaaaaa gcttcagaca ctataaacct tgctggtaaa
     2821 ggaagggcgc tttataccag tatttatttc ttattagaag aaacgaatcc ttcacatttt
     2881 caccgattga cagcagatga aatctggtat tttcatgcag gatccccact tactgttcac
     2941 atgattacag cagatggtca ctacgaagca gtcactttag gcctggacat atccaaaggg
     3001 caacaacttc actactgtgt tcctaagggc actatttggg gatcaacagt tgataaggat
     3061 tatgctctgg tttcttgtct tgttgctcct ggttttgaat ttgaggattt tgaattattt
     3121 gaaagggcag atctactggc gacctatcca gagcacaagg agatgattga gcatttgacc
     3181 agatactagt cttgataagc aaatttaatc tgatttagca atgttaggat ttctgataat
     3241 tgtgttataa tgttaccaat aggagataat agatgacaaa acaagtctta ttagtggatg
     3301 atgaagaaca cattctgaga ttgcttgact accatttaag taaggaaggc ttttctactc
     3361 aattggtaac aaatggacgg aaggccttag ctttggcaga aacagaaccc tttgatttta
     3421 tcttgcttga tatcatgtta ccacaattag atggcataga agtttgtaag cggctgagag
     3481 ccaaaggcat caaaactcca attatgatgg tttctgcgaa aagtgatgaa tttgataagg
     3541 ttttggcctt ggaattaggg gctgatgact acctgaccaa gccttttagc cctagagaat
     3601 tgctggcacg tgtcaaggct gtcctcaggc gaactaaagg agaacaagaa ggagatgatt
     3661 cagataatat tgctgacgat tcttggctat ttgggacctt gaaagtatac cctgagcgtc
     3721 atgaggtcta caaggcgaat aagttactga gtttgacccc aaaagaattt gaactcttgc
     3781 tctatcttat gaaacatccc aacatgacac tgactagaga gcgtcttttg gaacgtatct
     3841 ggggatatga ctttgggcag gaaacacgtt tggtggacgt tcatattggt aagttgaggg
     3901 aaaaaattga agacaatcct aaagcccctc aatttattcg aaccattcgg ggttatggtt
     3961 ataagttcaa ggagttatag atgaaacgct accttcaatt ttggctagtc aatctaagtg
     4021 ttagcctcat tctgattgca ggaatggcat taacttggat cagtaaaggc atcggtctct
     4081 ttcttctagc cctttctttg ggactaggtg gctactggct cttttgcctt tggaaatggg
     4141 aagttgcttt tgagaccttg caccaacctc tcttgaccag tagtgaatac tttttagaaa
     4201 aagggcaaga agacttaaag tctttggcta agtatgtgtc tggcctaaaa accaaagtct
     4261 cccaacagga tcagcaatac aaggacctag ccgaaacaat ggaggttctt ctgtcgcacc
     4321 taaccatggg gacgttttta gtttccgctc aaggtcagat gttattatcc agtcgctctc
     4381 tgcctcatta ttttcccgat gtggacggcg acataagttc acttgatgac ctcaaacgga
     4441 tggatattcg gaatttagtt caccaagcct ttgatcaaaa aacaaggtta aaacaagaag
     4501 taagtgggtt tcatgagggt gacttgattt tagaagtgac agcagttccc gtttttagcc
     4561 ccacccaatc tgtggaagct gtgctcgtct tgctatatga tttaacaacg attagaactt
     4621 atgaaaagtt aaatttagcc tttgtctcaa atgcctccca tgaattgagg acaccagtta
     4681 cttcaattaa gggctttgct gaaaccatta aggggatgtc agctgaagaa gaagcgctca
     4741 aggatgactt tctagacatt atttacaaag aaagcttgcg tcttgagcat attgttgagc
     4801 atcttcttac cttatctaag gctcaacaaa tgcctataca atggacgacc ctttctttgg
     4861 cagaatttgt acaggatttg actcaaagct tgcaacctca gctcaagaag aaggatttac
     4921 agctaaaggt gcaggtgcca gatgatgtca ccctcgtatc agatagtcaa ttactttccc
     4981 aaatcttact caatctttta tccaatgcca tccgttacac tgaacaaggg ggaaaaattg
     5041 aggtcaagac ccaaaaggtg aacgaaggca ttaagatttc tgtatcagat acagggattg
     5101 gtattagtca attagagcag gatcgtattt ttgaacgttt ttaccgagtt aataaaggtc
     5161 gaagcagaca aactggtggc actggtcttg gccttgccat tgtcaaagaa ctcagtcaat
     5221 tattaggtgg ccaagtcacg gtgacgagtc agcttggcag aggcagttgc ttcacgattt
     5281 ttcttcctaa ccaatctttc gcacaggact aataattttt aaagctattt ttaggagcag
     5341 ccatttttca aaagtggctt tttttgattc tttacacaat ctttacatga atcagggata
     5401 aacctttaca aagacttgtt agactataaa tgtagtaagc ctacacaaga aaaatacata
     5461 gagataaagg tgattattat gaaattcaaa aaaatgctta ctcttgcagc cattggctta
     5521 tcaggatttg ggcttgttgc ctgtggcaat cagtcagctg cttccaaaca gtcagcttca
     5581 ggaacgattg aggtgatttc acgagaaaat ggctctggaa cacggggtgc cttcacagaa
     5641 atcacaggga ttctcaaaaa agacggtgat aaaaaaattg acaacactgc caaaacagct
     5701 gtgattcaaa atagtacaga aggtgttctc tcagcagttc aagggaatgc taatgctatc
     5761 ggctacatct ccttgggatc tttaacgaaa tctgtcaagg ctttagagat tgatggtgtc
     5821 aaggctagtc gagacacagt tttagatggt gaataccctc ttcaacgtcc cttcaacatt
     5881 gtttggtctt ctaatctttc caagctaggt caagatttta tcagctttat ccactccaaa
     5941 caaggtcaac aagtggtcac agataataaa tttattgaag ctaaaaccga aaccacagaa
     6001 tatacaagcc aacacttatc aggcaagttg tctgttgtag gttccacttc agtatcttct
     6061 ttaatggaaa aattagcaga agcttataaa aaagaaaatc cagaagttac gattgatatt
     6121 acctctaatg ggtcttcagc aggtattacc gctgttaagg agaaaaccgc tgatattggt
     6181 atggtttcta gggaattaac tcctgaagaa ggtaagagtc tcacccatga tgctattgct
     6241 ttagacggta ttgctgttgt ggtcaataat gacaataagg caagccaagt cagtatggct
     6301 gaacttgcgg acgtttttag tggcaaatta accacctggg acaagattaa ataaaatgtt
     6361 tgctccataa atctctaaag agatgcagac gtttcatcgt acaataagat aaagaaggca
     6421 agtagggagg tgtcgtatct cccttacttt cttcactaga aaggacaaga tgtgacaaaa
     6481 caagccttca aagaagcagt ttttagggca atttttttca tgagtgcaac agtagctgtt
     6541 gtagctattt tgctaatctg tttctttatt tttagtaatg gcttaccttt catagctaac
     6601 tacggctttg cccgtttttt attaggcagt gattggtcgc caacgaacat tccggcaagc
     6661 tatggtattt taccaatgat cgttggttcc ttattaatta ccttaggagc gattgtgatt
     6721 ggggtgccaa caggcatctt gacatcggtg tttatggttt attattgtcc aaagcccgtc
     6781 tatagcttct taaaatcagc tatcaacttg atggcagcca ttccatctat tgtttatggt
     6841 tttttcggcc tacaattatt ggtgccttgg attagaacct ttttaggaaa tggcatgagt
     6901 gtcctaaccg cttcgttact attaggaata atgattttgc caaccattat cagtttgtca
     6961 gaatctgcta tccgaacagt tcccaaaacg tattattctg gtagcttggc tctaggagct
     7021 agtcatgaac ggagtatttt tagtgtcatc ttgccagctg cgagatctgg tattttatca
     7081 gcagttattt taggaatcgg tcgcgcagta ggtgaaacca tggcagttat tttggtggca
     7141 ggcaaccagc cgattattcc aagtggactc ttttcaggaa ccagaacctt aacaaccaat
     7201 attgttctgg aaatggctta cgcatcaggt cagcataggg aagcccttat tgcaacctca
     7261 gcagttatct ttttccttat tctcttgatt aatgcctact ttgcctactt gaaaggaaaa
     7321 tcatcttatg agtaaatacc tgctaaaact tctcgtttat tgtttttcag ctttaacctt
     7381 tggctctctc tttttaatca ttggttttat cctcatcaaa ggcttacctc atctaagtct
     7441 atccctcttt tcttggactt atacttctga gaacatttcc cttatgccag cgattatttc
     7501 caccgttatt ctggtttttg gtgctcttct tttagccttg cccataggga tttttgctgg
     7561 tttttatctt gtggaatata caaaaaaaga ttctctttgt gttaaaatca tgcgattggc
     7621 ctcagatacc ttgtctggga ttccttccat tgtttttggt ctgtttggca tgctcttctt
     7681 tgtagtcttc ttaggttttc aatactctct gttatcagga atcttaacct cagttatcat
     7741 ggtgttgcca gtcattattc gctcaacaga agaagccctt ttatctgtta gtgatagcat
     7801 gcgtcaagca agttatggac ttggggcagg taagttacgg actgttttta gaattgttct
     7861 accagttgcc atgccaggta ttttagctgg agtgatacta gctattggcc gtatcgttgg
     7921 tgaaacagct gccctcatgt atacattagg tacctctacc aatacgccaa gtagtctcat
     7981 gtcttcaggc cgttctctag ccctacatat gtatatgctg tcaagtgagg ggctacatgt
     8041 caatgaagcc tatgctaccg gcgtgatttt gattattact gttttaatga taaatactct
     8101 atcaagctta ttatctcgga aacttgtgaa aggagcttcc tagtatggga acattttcag
     8161 tcagacacct agacttattt tacggggatt ttcaagcctt aaaaaatatt tcgattcaat
     8221 taccagaaag acagattact gccttgatag gcccatctgg ttgtggcaaa tcaacttttc
     8281 taaaaaccct taatcggatg aacgatttgg ttccttcttg ccatattgaa ggccaagtcc
     8341 tcttagatga gcaagatatt tatagtagca aattcaacct taatcagcta cgcaagcgtg
     8401 tagggatggt ttttcaacag cctaatccct ttgccatgtc tatctatgat aacgtggctt
     8461 atggtccaag gacacatggt attcgagaca aaaaacaatt agatgcctta gtggagaaat
     8521 ctttaaaagg ggcagccatt tgggaagaag tcaaagatga tcttaaaaag agtgccatgt
     8581 ccttatctgg cggtcagcag caacgccttt gcattgcgcg agctttagca gtagaacctg
     8641 atattctgtt aatggatgag ccgacttcag ccttagaccc tatctccact ttaaaaattg
     8701 aagacctcat tcagcaacta aaaaaggatt atacgattat cattgttacc cataacatgc
     8761 aacaagcttc acgtatttca gataaaactg cttttttctt aacaggagaa atttgcgaat
     8821 ttggagatac cgttgacgtg tttaccaatc caaaagatca gcgcacagaa gactatattt
     8881 caggacggtt cggataagga aggaaaaacc tatgagaaat caatttgact tagaattgca
     8941 tgaattagaa caatcctttt taggactagg gcaacttgtc cttgaaacag cttcaaaagc
     9001 cttactggcc ttagcctcca aagacaagga gatggcaaag ctaattatca ataaggatca
     9061 tgctatcaac caaggtcaaa gcgctatcga attgacctgt gcccgtttgt tagccttgca
     9121 gcagccacaa gtgtctgacc ttcgatttgt gattagcatc atgtcttctt gttcagacct
     9181 tgaacgtatg ggagaccata tggcaggcat tgccaaagct gttttgcaac taaaagaaaa
     9241 tcaactagcc cctggcgaag aacagttaca ccaaatgggt aaattatccc tcagcatgct
     9301 agccgattta ttggttgcct ttcctttgca ccaagcctca aaagctatta gtattgctca
     9361 aaaagatgaa cagattgacc aatattatta tgccttatca aaggaaatca ttggacttat
     9421 gaaagaccaa gaaacctcaa ttcccaatgg aacacaatac ctttatatca tagggcatct
     9481 ggaacgcttc gctgattaca ttgctaacat ttgtgaacgc ctagtctacc tagaaacagg
     9541 agaactagtg gatttgaatt aattcaacta atccttaaaa gagaagagta cgattaagtg
     9601 ctctttttta tggttgtaaa aaagttcatt tgaccaattt aagcagtgta gatagtgagg
     9661 agctgtttca attctatcgt gaacgaggga atgctgaaaa ctttatcaaa gaaaggaaag
     9721 caggattctt tggggataag acagatagtt cgaccatgat taagaatgaa atacgtatga
     9781 tgatgggctg tctggcttat aatctctacc tctttttaaa acagctagct ggtgatgaag
     9841 taaaggcctt gactatcaag cgttttcgac gtctcttcct tcatattgcc ggaaaatatg
     9901 tctctactgc tagacgacat attctcaaat tctcaagtct atacgcctat tcaaaacagt
     9961 ttcaagcctt atttgataca atctgccaga taaatctgat actccctgtt ccatatagag
    10021 ctagagggca ggggaaaaca tgcctaacag aataagtcac cttattttaa aaatcgatca
    10081 tcaaaccaag ggaggagtct gcccttttta ggaacaaatc aagacaaatc tcctcaatca
    10141 tgtctcgaac atcagaaatt aagcaaaatc accagaagga cagtatttca actagctttt
    10201 ctggtaattt ttgaactgtg tagttcgtta gtgccagata tgaataattt gggatgataa
    10261 atctttcttc ctcaggtagc ctatcataat actcttcaaa aatcttagca aaaacactct
    10321 ctttcttttg ggcgatagtt tcatcttcgt atgtaggagt cctcatcaag aaatacttca
    10381 attctaggta ttccttatcc aactctatat aacttggcat caacttgtaa tcttcaaccc
    10441 ccaaacgttc agcgatatat tttaactttg ttagtgttgg tctggattct ccattttcaa
    10501 ttctaattaa ttgacggata cttaattcag actcatcacc acaaaattct gaacgactga
    10561 tttttttagc caaacgtaat cttttaattt tttcgccaaa ctctcgcaac ctacaagaac
    10621 ctcttgagtt gtttacctct atttatagca tatactgaat caaactatct atcagatttc
    10681 ttctcacttt aactaaagac taagagttta tcccttcatc tcggtttttg tgtatttttc
    10741 caccataccc cagtaatgca agtgcaaaat cccctagaat atgatataat aagagaaaga
    10801 aatctatcaa ggaggaaatc atggaaaaac aaaccgtcgc cgtcttgggg cctggttctt
    10861 ggggaaccgc cctttcacaa gtcttaaatg acaatggaca cgaggtacgt atttggggaa
    10921 atcttcccga gcaaatcaat gaaattaata cacaccatac taataagcac tactttaaag
    10981 atgtcgttct agacgaaaat atcattgcct acaccgactt agcagaaaca ttgaaaaatg
    11041 tggatgcgat tttgtttgtt gtcccaacaa aagtgacacg acttgttgcc cagcaagttg
    11101 cacaaacctt ggaccataag gttatcatca tgcacgcatc aaagggatta gaacctgata
    11161 gccataaacg attatcaacc attcttgaag aagaaattcc tgaacatctc cgtagtgata
    11221 tcgtcgttgt ttcagggcct agtcatgcag aagagaccat tgtgcgtgac ctaactttaa
    11281 taactgctgc ttctaaagat ttacaaacag ctcaatacgt tcaggagcta tttagtaatc
    11341 actacttccg actttatacc aatacggatg ttatcggggt tgaaactgct ggtgctctta
    11401 aaaatattat tgctgtcggt gctggagctt tacatggtct tggatttggt gataatgcta
    11461 aggcagccat catcgctcga ggtttagcag aaatcacccg cctaggggta gcactcgggg
    11521 ccagtccatt gacctatagc ggcttatctg gtgtgggaga tttgatcgta acgggaactt
    11581 ccatccactc tcgtaactgg agagctggag atgctctcgg acgaggagaa tccctagctg
    11641 atatagaagc taatatgggc atggtaatcg aaggaatttc aacgactcga tcagcctatg
    11701 aactagccca agaacttgga gtctatatgc ccattacaca ggctatttac caagttattt
    11761 atcacggaac caatatcaaa gatgccattt atgacatcat gaacaatgaa tttaaagcag
    11821 aaaatgagtg gtcttaaccc tctatagaaa ggatttttat gacatcaaaa gttagaaagg
    11881 cagtcatccc tgctgctgga ctaggaactc gatttttacc agcaaccaag gcccttgcca
    11941 aagaaatgtt gccaatcgta gacaaaccaa ctatccagtt tatcgtggaa gaagctctca
    12001 aatcaggtat tgaagatatt ctagttgtca ctggtaaatc aaaacgttct attgaggacc
    12061 actttgattc aaactttgag cttgaataca atcttaagga aaaaggcaaa acggatttgt
    12121 taaaattggt agatgaaaca actggcatgc gccttcattt catccgccaa actcatccac
    12181 gcggtctcgg agatgctgtt ttgcaagcca aggctttcgt cggaaatgaa ccttttgtcg
    12241 ttatgcttgg tgatgacttg atggatatca cagacgagaa ggccgttcct ttgacaaaac
    12301 aactgatgaa tgattacgaa aagacacacg catcaaccat tgctgtcatg cccgtaccac
    12361 acgaagacgt ttcatcatat ggagtcattg ctcctcaagg cgaaggaagc aatggactct
    12421 atagcgttga aactttcgtt gaaaaaccag ctcccgagga gactccaagt gatttggcaa
    12481 tcatcggtcg ctatctactc acaccagaaa tttttgagat tctcgaaaag caagctcctg
    12541 gtgctggaaa tgaaatccaa cttactgatg caatcgatac tcttaataaa acacagcgtg
    12601 tttttgcccg tgaatttaca ggagctcgtt acgacgttgg ggataagttt ggctttatga
    12661 aaacatctat tgactacgcc ctcaaacatc cacaagtcaa agatgatttg aagaattacc
    12721 tcatccaact tggaaaagaa ttgactgaga aggaataaaa taaaaagata aggttcaaaa
    12781 aatgccttat cttttttcat tacacaaatt ttctttcaac ttcgtcacat tcccattccc
    12841 ttgtagaaaa gcaaaatggc gagtcctacg aacaagacta ccgctcctaa tctctggctg
    12901 gtgttataca tccgtttttc tcctctaact ggaaagataa ctgctagaaa tgcgccacca
    12961 actgctccac cgatatggcc tgctaggctg attcccggaa tcagaacact tccaataatg
    13021 ttaaccacaa aaagtgtcag ataagattgc cctagctgtt ggatataagg attgcgagtt
    13081 gcatagcgaa gaacaataat cgcggcaaat agcccataaa gagaggtaga ggcgcctgct
    13141 gctaaggatt taggactaaa tacaaaaaca aagagattgc ccatcattcc tgataaaaga
    13201 tagagaaaga aaaactgctt agaaccgaaa atctcctcta cctgccttcc aagataataa
    13261 agtgaaagca tattaacaat gaaatgttcc cacccaatat gaacaaaaat ggcagacaag
    13321 agacgccaaa cctgctcggg aaagaggcga atagctggac catacatggc tccaaatcga
    13381 aataatgtat ctgccctgtc aaagtttccg cctgcagtga ccaacattag taaaaatacc
    13441 aaggccgtca ctaagaggaa gaaactcgtc acagggtaac gtctatcaaa gatttccttc
    13501 atcaattaat acctcctgaa caggaatatc atggttttca ggtataaagt cctgaatttg
    13561 acaaggatat atcgtactca aagcacgacc agaaaaatgt tccagatagc ggtcataata
    13621 gcctccaccg tatcctatcc gatatccttt cgtcgtaaaa gccagaccag gaacatgaat
    13681 caaatcaatc tttgaaacat ccacaacttc caaatctccc tgtggctcca gtaatccaaa
    13741 ggaagttttt accaactgtt gcggatcata gaccacaaag tccatgcgcc ccttgggata
    13801 ggtcttaggt gtcaaaaccc tcttgccgtc cttcagcgcc tgctcaatca gttcccgcgt
    13861 ttgaaactca tgagaaaaag agaggtaggt tgcgatgacc ttggcttctt gataaaaggg
    13921 gtgttgtaaa attcgctcgg ttaaagcttg gtctatagcc tgtttttgtt cttgagataa
    13981 agccttcatt tcatgcaaga cttgcttgcg taattccgat ttcatagaca agccctctat
    14041 tctgctgcct tctttttcag gaaactagac accgcagcca ccccaatagc taagacttct
    14101 tccttaggac tcatttgagg gtgatgaaga gcgtagggac tatcgatacc tagccaaaac
    14161 atcacaccat caacctttga aaggagataa ccaaagtcct cgcctgtcat agcaggttcg
    14221 atatcaatca actcgattcc gtctttttcg tcaaagaagt ccatcagttc acgcgccaag
    14281 gctggattgt tctcaacagg taggtatcca ccttgtttga gttccacttc gacttccata
    14341 tcaaaggcag ctgcaaccgc ttctgcaact gtttttaccc tcttttgcac caagagactc
    14401 atgtcctgtg tcaaggcacg aatagttcca tgtaaaaaag ctgtgtctgt gatgacattg
    14461 ttggtggttc cagcttgaaa aacgccgaag gtcaccactg ctccctcgat tgggttgaca
    14521 ttgcggctaa caactgactg cacttgggtc acaaagtaac tagccgccac caaggcgtca
    14581 ttggcttcat gaggaaaagc tgcgtggcca cctttgcctt tgaaacggat cttcacctcg
    14641 caagttcctg caaagagtgt atgagtatta gtcgcaatct ggccgacttt caaatctgga
    14701 cgaacatgga gaccatagaa ttgatctggc aaccaatctc caaaagcacc gtcctcatac
    14761 atgagcatac caccagcttc attttcttca gcaggctgaa ataggaagag cagattattt
    14821 ttaggttgct cttcaagggc gcgctcaaga cagcctaagg caatggtcat atgaaaatca
    14881 tggccacagg catgcatgcg accttggtgt tgagaagcaa aaggtagacc tgtttgttcg
    14941 acgataggca ggccatcaat atctgtccgc caaccaatgg ttcgctccgg ctgacttccc
    15001 tgcaggtaga ccaaaatccc tgtccgccaa gtacgaattt gaacaaaatc cttgcccgta
    15061 gtcaatttct caatcacatc cagcaaataa gcctgagtct tgaactcctc caagccaatc
    15121 tctggaatct ggtgtaaatc tcgtctagtc tgaatcaaat ctaacatcta tctgtcctcc
    15181 gatatagcag aaagaggctg gaaaaagggt tccgcctctt ttttactttt acaattacaa
    15241 ggtacgaagc gcatcctcta gcgctgtttt ttgttgagtt tgggcatcaa tttctttgat
    15301 aatacgagct ggaacacctg ctactaccac gttttctggg acatcttggg taacaatagc
    15361 tcctgctgcg acaactgaac cactaccgat ttggactcct tcgataacca ctgcattagc
    15421 cccgatgaga acattgtctc cgacacagac tggttcagca ctagctggct caatcacacc
    15481 tgccaaaact gcacctgcac caacgtggct attttttcca acgatggcac ggccaccaag
    15541 gatggcaccc atgtcaatca tggttccagc accgatttca gcaccgatat tgataacagc
    15601 tcccatcatg ataacagcat tgtcaccaat ttccacctgg tcacggataa tagcacctgg
    15661 ctcgatacga gcgttgatag cacgcttatc tagcaaagga actgcagaat tacgagcatc
    15721 ttgctcgaca acataatctt gattttctac caaaccttca agaagcggag ccacgtcctt
    15781 ccagtctccg aataggacat ttcctagttt gacaacagag ctaggcacag cagttgcgag
    15841 ttgcccctca aaggttactt tgacactggt tttcttttca gcattggcga taaattggat
    15901 aatttcttga gcgttcattt ttgtagcagt cataggtgcc tcctggttcg ttataatgat
    15961 acctattcta ccaaaaaagg cctcaaattt gaaacctttt tgtctgtttt taggtatgat
    16021 tttttaggga tgtgagataa aacgtgctgt cggtaaaagc aagcccctac cgatacaacc
    16081 taaaaacact cttcacaact atctccccgt gttttattga ctattctagt atagcacact
    16141 tttagaatta agaaaagact ttttatctac tttctttcgc ttcttctata gacaaaaata
    16201 tcatgggtaa aataatcaag gctatagcta gaaggaggga ccaatccact actaatccta
    16261 agaacaaaac actcaagaga gcagaagaga gaggttcact ggcactgata acggcaacca
    16321 ccaaaggaga aaccaaggac acagccttca tggaaatgaa aaaagcaaaa gccgttccaa
    16381 agaaagcgat aatgaggcaa atcaagatac tccaaatatc aagagtaaag gaaagctgat
    16441 aaaccggcga gaggacattg ctaaacaaac ctgccaaaat catcccccac ccaaccgtag
    16501 gaacaaaacc ataacgctta gcaaaaggtt ggggcaagat aacattaaac ataacaccca
    16561 tggcactcag caaacctgtt ataagagcta gcggcgtcat ggataactga gagagatctc
    16621 cctttgtcgc catcaagcaa acacccagca tggcaaccaa aacatagaaa acagcgcttt
    16681 ttgacgctcg tttttgataa accaagcgat tgtaaaagag gataaagaca gggctaataa
    16741 actgtaaaat agttgctgtc gtagcatttg agtattctac acagagatag aaaaaatact
    16801 gaactgaaaa aatccccaaa atagcatagg ctaaaaaggg caggtaattt ttcttgtctc
    16861 gccaaatatc tagcacttgc gattttaatt gtattgcaga ccaaatgagt acaagactcc
    16921 ctgccagtgt caaacgcata gaggtaatcc agcccgaaga cacctgataa tgagtaaaga
    16981 agtactctcc taaaattcca cagattcccc atattaagcc ggataggagc gaataaattt
    17041 ttccgttaac aatctttttc tgatactgat tcataccctt attgtaacac gaaaagaaaa
    17101 aagtggcaat ccattgattg gccacttcat ttagagaatt atcgtctcgc ccttgaagaa
    17161 gaaggtcgtg tagtacttga gttactgcta tcgctagaac tactacttga actgctggag
    17221 ctggatggag ttggtagact ccccacaata ctagaccaag cattctgata atccgcatca
    17281 cttccaccaa tagcaaagcg ataacttgtc gctggcgctc ctgccttatt agcccaatag
    17341 ctggtaacag tcgaacctgt gacctctact tcttttcctt caacagaaac cttccctggt
    17401 ttttgacctg ttgatttcaa gacttccgat ttcactacac taggatctaa agcaaagcgc
    17461 tcgttccccc aaatgcttgg ggaagcttgc tgaatcgcat ttaccagatg agccatgtaa
    17521 ttagagttat tagaataacc tgctctacgt gacaatgaat gattatcatc atgcccaatc
    17581 caaccaccta gggttaatct aggtgtcgaa agcatgagcc acatattttc gtcttggttg
    17641 gttgtaccag tcttcccaat ccaatctgca ttagccagag taggatttaa agaagtcagg
    17701 ttagacttga aggttgttgt cacacgagaa gatagaactt ctcgtagcaa tccctgcata
    17761 atcgtcgcag tagcttttga atagacttga accggtttat cctgatactc atacaccact
    17821 ctaccatctg ctgcttcaat ctttgaaatc acatgcttct gatgataaac tccattatta
    17881 gctaaggtct gatagccatt ggtatgctgg gcaactgtga cttcaatacc accacccatt
    17941 ggcaagctct caataccgta ctcaggaatc tcgtaaccca tcttttccat ataacccttg
    18001 acatcaacac cattttcacg gagcatacga taggtccagt aagcagggat attccatgaa
    18061 tagttcagag cttctcccaa ggtcatcatt cctgttccct tgctattagc atacataatc
    18121 ggattgccat tagcaaagtt tgttggatag ttagatagaa tcgtttcact tcccatcaag
    18181 ccctggtcaa tagcaatacc gtaggccagc aagggcttgg tagtagaagc tggcgaacgt
    18241 ttggtatcaa aagcatgatt attttgattt tcttgataat tacgaccacc tacaaagcct
    18301 agaatagcac ctgtttggtt gtccatcaag acattcccta cttctacacg acctgttcca
    18361 tcgtctaaaa gatagccata atcagcaacc gcactttgca tggcagaatg aattttctga
    18421 tctatggtag tagtaatctt ataaccacca ttttcaattt ccttggctgc caaatctcga
    18481 taaaacttct gagttgcctc atttttcaac tccttagcgg agacattgtc tctctgagct
    18541 agatagtcat acatacgttc ttgagcttct gccaaagttg taaagtataa atagtctcgt
    18601 gaaattcctg taaccgtgcc cgatggtaaa aagtcctgtt taaggtcata atccttgtac
    18661 tgagaatact cgtctttgct taatgcacct gtacgataca tactgtaaag aactgcctta
    18721 gcccgtctta agccaatttc taggtcttca tcactcttca actccccagt attttcataa
    18781 ggagagtaag taatgggact ctgtggaagt cctgctaaaa atgctgcttg aggaacagtc
    18841 aactgactgg catctacacc gaaaattccc tcagctgctt gccgagcccc tgcaatattc
    18901 tgtcccttat tatttcggcc aaagggagcc acattgagat aggtcgttaa aatctcatct
    18961 ttattcatgg cgcgttccaa ggcaagagca tccacaatct ctgccgcctt acgagccaag
    19021 gtcggcgcat ccccaaccac ctgctgttta attagttgct gggtcaaggt tgaaccccca
    19081 ctagaggaac ccaaacctac aaatttcccc aaggtcgcac gaatcaccgc cttgggtact
    19141 acacccttat gttctttaaa gtgttcatct tctgtcgcaa tgatagcctt cttcagattt
    19201 tccgaaattt gctcagatga gatagaagtg cgcaacaaat cactctctat ggaagcaatc
    19261 accgtcccgt ccgaataggt aatctctgaa atagaagaga tgtccttgac ctgattcacc
    19321 aattcttctg tctgaggcac ccgaaccttg tcaaataagg ccactccgta ccccaaagca
    19381 atcccaactc ccaacattcc tcctagaaaa ccgagtacaa agagtaagtt aaataaggct
    19441 tttatactca gtaaaatagc tgggaaaatg gctgacttat ctaaggtttt agattttttg
    19501 gtacttgaac ctttcttgcc aggtctagct gattttttat ttttttgttt ttgctggaaa
    19561 aattccagca tttttcgttt taattcattt aattgatttt gcatggattt cctcacttta
    19621 tctattatac cacaaaaggg aaattttcaa taaaatagcc actttcttcc ctattctgct
    19681 aggctattgc ccaagtttgt gatacaatag gtagaaacaa taattttaaa aaggagaaaa
    19741 gacacatgca catttttgat gagctaaaag agcgtggttt gatatttcaa acgactgatg
    19801 aagaagcttt gcgtaaagcc ctagaagaag gtcaagtttc ttattatact ggctacgatc
    19861 caactgctga cagccttcac ctaggccacc ttgtcgcaat cttgacaagt cgtcgcttgc
    19921 aactagcagg tcacaaacct tatgcgctcg ttggcggtgc tacaggtctc atcggagatc
    19981 cgtccttcaa agatgctgaa cgtagtctcc aaacaaaaga cacagtagat ggctgggtca
    20041 agtctatcca aggacaactt tctcgttttc ttgactttga aaatggcgaa aacaaggctg
    20101 tcatggtcaa caactacgac tggtttggca gcatcagctt cattgacttc ctccgtgata
    20161 ttggaaaata cttcacggtc aactacatga tgagtaagga atctgttaaa aaacggatcg
    20221 aaacaggaat ttcttacact gagttcgctt accaaatcat gcaagggtac gacttcttcg
    20281 tccttaacca agaccataat gtcactcttc aaatcggtgg ttctgaccag tggggaaata
    20341 tgacagctgg taccgaattg cttcgtcgta aggcggacaa gactggtcac gttatcactg
    20401 ttccactaat cacagatgca actggtaaaa aatttggtaa atcagaagga aatgccgtct
    20461 ggctcaatcc cgaaaagact tctccatacg aaatgtacca attctggatg aacgtgatgg
    20521 acgctgacgc tgttcgcttc ttgaaaatct ttactttctt gtcacttgat gagattgaag
    20581 atattcgtaa acaatttgaa gcagcgccac acgaacgctt ggctcaaaaa gtcttggctc
    20641 gtgaagttgt tacacttgtt cacggagaag aagcctacaa agaagcactt aacatcactg
    20701 agcaactctt tgcaggaaac atcaaaaacc tttctgtcaa agagctcaaa caaggacttc
    20761 gtggtgtgcc aaactaccaa gtacaggcag acgaaaacaa caatatcgtg gaactgctcg
    20821 tctcatctgg tatagttaac tcaaaacgcc aagcccgtga agacgtccaa aacggagcca
    20881 tctacgtaaa cggcgaccgc atccaagacc ttgactatgt cttgagtgac gctgataagt
    20941 tagaaaatga actgactgtt atccgtcgtg ggaagaaaaa atactttgta ttgacttact
    21001 aaactattca acatttatct ataaacaaag gagttaacct cgagaaaggt aactcctttt
    21061 tgctgttaat aactctcatc tatctatttt taatagacag gctacgcagg acaatgcgca
    21121 aggttgttag attatgtaag atagagagat ttgaaggact gaaccaatta aataagccaa
    21181 agccaatcaa actactattt acgataacgg tatcctgaat atttttcttg atgagtgttt
    21241 gcaaagatga tgataacgaa tccaactctt ggaagaaatc caaacgatta tctaacaata
    21301 agatatcact catctgctta gaaatatctg cactctcatt catcaccaca ccgatatctg
    21361 atagagttaa agccgctgag tcattcaatc catctccaac catcaaaata gtgtgacctg
    21421 ctttctgcag tttctctact aactcaaatt tcccatcagg tttcaagtct gtatagacct
    21481 gatcaaaggg caaatctttg actaattcct ctgtcctaat caaggtgtct cctgttgcca
    21541 gaatcaattt tttcccctgt gccttaagtt tatccaaggc tgtttttgct tcttttctca
    21601 aaggagtatg aatgcagaac attccaatca attcattttg ataagccaag aataagagat
    21661 tgtagtgact cttgtactct tcaattaaag cattttgttc tgaactgata tgaatctgct
    21721 catcctgcat caagacataa ttcccaataa gaactggttg gccatctata tgagatttga
    21781 tccccttgct tgcgatatat tggagtttcc catgcatttc ctcatgttca attccctcta
    21841 tctcagcttg cttgacgatg gcattagcaa taggatgata aatgtgttcc tcaagacagg
    21901 cactgattct gagaatatct tcctcactat agtctccaaa aggtaacacc ttttcaacta
    21961 taggataact agttgtgatt gttcctgtct tatcaaacaa gaaagtatca acttccagat
    22021 atttctccag aacatctcca tccttaatca ccatttcacg gttcaaccct tccttgataa
    22081 ctgtcaaata agctaccgga gtagagattt tcaaagcgca ggagaaatcg accaatagga
    22141 aagaaatagc cttagaaaaa gaacctgtca ataggtaagt cagcccagcc cccaagaaat
    22201 tatatttgac gactttatcc gccatcttga tgaaatagcg ttgtttcgtt ttcttgtttt
    22261 cttcagattt cttcatcaac tcaatcagct gtaaaatacg gctgttcatc tgattatctg
    22321 ttacacaaat gcgtaactct ccagtttcta atactgtatt tgcacaaacc aaatcagact
    22381 ctcttttttc aactggaaaa ctctctcctg tcaaggaact ttcgttgacc atacctaaac
    22441 ctgaaactac ttgtccatca aacagaattt catttccttg agataagatc aagacatctc
    22501 ctatttgaac atcggaactc ttgatactaa caactgtatc gccctgtact aggaatacat
    22561 cgctctcttt tgcaagaaga ctctgttcta aatctgttgc agtttttttc aaggaccact
    22621 gatctaaatg attccccaaa tcaagcataa acatgatatt gctagctgtc ttggattggt
    22681 tcataaacaa agacaataaa atagccgaac agtccaagac ttccatcgtt agttccttac
    22741 gcgctagtgt ttgataggct tctctaatat aacccaaagc ctgataacaa gtccatatat
    22801 agcgaatagg atacggcaca aaactacgaa aaagtacacg cttaaccgct gcacctgaaa
    22861 caatagaata agcactctct tctctacgaa tgggaagagt catcaactca gaaactttcc
    22921 ctttatcaat tctttttaaa aaggcttctg cattatctaa tacagaaaag ccttctttta
    22981 tgcgtagagt aaagtgctgt tgatccatgt aaaactggat agactcaatc cccttttcat
    23041 ctctcgccaa ggaacgaaga tagtcttgaa tatccaaggt aagtgaaaaa gaagatgata
    23101 gtcggatatg ttggtatcct ctatgtagca ctttaaaaga catattattc acctataagg
    23161 ctatctaatt gctcttcttt tttctcttgc tcgtacaaat atttggcatc ttgcaagaca
    23221 tcgtctccat gttgcttcac gacagaaaca gatgcatcta gctcgtcttt caacttgtaa
    23281 gccttagcca aagctttaga ataacctttt ttagcttcct tacttgctaa gattttcaaa
    23341 ccaagggtac caaatgcgac accacccaaa aataatgaag attttttcgc aacttttgca
    23401 acggttaata cttcttttaa catacttatt tcctccttat cattattata tagcaattta
    23461 gatataaaag caatttcatt ctataaattg gagaattagt tttatttcta ctgaatctcc
    23521 catctactta ttcctaaagt tgctttcatt tgcctctttt gatacactta aactatgaat
    23581 acaaatctca agcccaaact tcagcgtttt gcttctgcga ctgcctttgc ctgtcctatc
    23641 tgtcaagaaa atctgactct gttagagact aatttcaagt gctgcaaccg tcattctttt
    23701 gacttggcga aatttggcta tgtcaatcta gcacctcaaa tcaagcaatc tgctaactat
    23761 gacaaggaaa attttcaaaa ccgtcaacaa atcctagaag ccggctttta ccaagctatc
    23821 ttagatgctg tatctgactt gcttgcaagc tcaaaaacta ccacaacaat tttggatatc
    23881 ggttgtggtg aaggattcta ttctcgcaaa ctacaagaaa gtcactctga aaaaactttc
    23941 tatgcctttg acatctccaa agattcagtc caaatcgctg ctaaaagtga acccaactgg
    24001 gcagtcaatt ggttcgttgg cgacttggca cgacttccta taaaagacgc taacatggat
    24061 attctgcttg atatcttctc acctgccaac tatggagaat ttcgtcgcgt tttatccaaa
    24121 gacggtatct tgataaaggt tatcccaact gaaaatcacc tcaaagaaat ccgtcaaaga
    24181 gtacaggacc agctgacaaa caaggagtat tctaaccaag atatcaagga gcatttccag
    24241 gaacacttta ccatcctatc tagtcaaact gcctctctga ctaagactat cacagcagaa
    24301 caactccaag ccctactcag tatgactcct ctcctctttc acgttgacca gagcaaaatt
    24361 gactggagca aactgacaga gattaccatc gaagcagaga ttttggttgg gaaagcattc
    24421 taatactctt caaaccacgt caacgtcgcc ttgccgtacg tatggttact gacttcgtca
    24481 gtttcatcta caacctcaaa accatgtttt gagctgactt cgtcagtttt atctgcaacc
    24541 tcaaagctgt actttgagca acctacggct agtttactct ttgattttca ttgagtataa
    24601 actagacttc gcaaaagtag aaaacttacc gaaaatcttc aatatgacaa aaacgtataa
    24661 gaacaggtac acaaacctta atcttatgcg ttttgttata gtttccatac acattaaggg
    24721 gaaatagttg aaatcagttc tcttaataac cattgaatac catatactac atttacccca
    24781 aatatgatat aggccgtata aatcaagtat ttcgattttt cccgcctcaa agaatagatc
    24841 ttatacaaaa taaataaatt taaaataata aataatagag acaaaatctt cctccaaaat
    24901 caatcctaaa agtacacagt caagcatagc tctaatcttt attttcgatt cgatataaca
    24961 aacttatcaa tgaatagtaa gtgatataag gccagtacca gaccccaaac gctaccacga
    25021 aaagagaatt cttgatgatt gagagtaaac aaatcatggt taccaatata gaggcaggtc
    25081 aaaataacaa ataaaatcca aaataaatcc gtccatttat attttgaaaa atattttttt
    25141 aacataatag catatttttt tgactataat aacagtatat gataaaatgt aagcagatac
    25201 aaataaaaag gagaaaagct catgaacaaa ttaatgaaat ttatttcggt ttttttgacg
    25261 tcaattgtgt taattgtatc agcgattcca agtgtttcag ctgtatacgc ttctgaacaa
    25321 gtatcacaaa ttgaaacaaa tatggaactt caacctgtca cttctctaac agaagaacaa
    25381 ataaatacac ttgcaaacga aatccaatct tttcatccag acgtctcaca acaatggatc
    25441 aaagaagtaa ttaaccgaca attacaaggc gattatacaa tcccacctac atactctcca
    25501 tttagagcag cttggcaagg tattacagtt aatcaaatgg gtgctctatt agatactgca
    25561 atagctttag cattaggagg aactactgca ggccttgcaa atctaattaa agtaaaagga
    25621 aaacatgcag caaaaagtgc tattcgttca gcaatttcta gatatctagt tagttggttt
    25681 gtaaatgatg ttgctttaga attcgctatg aatttattat catcggggac ttatttagca
    25741 caattatggg ataaaaatga tgccattcct aacaacggaa ggattaactt ttaatcatga
    25801 gatatacaat aaaattaatt gggtataacg tattttcgtt gtttatattc tttatcttat
    25861 caatgttgtt taaagttccc tttaggtggt ggatcagcat tgcaatgacg acttcgtcgt
    25921 acattgtata taattactta aagaaaaaga gagaaaagga atgatcttat accagatcat
    25981 tccttttctg ctttctgtaa atccctcgga gtgtgtttgg cgctttgata cgaagtgtca
    26041 aagctgtata aacgttacta tttccaaaaa agtaacagaa aattcctgct ttgtaggact
    26101 gctttgggtg agtaataaac atgtcgactc accctatctc ctgatggcga aaagaattta
    26161 gcaatggtgc aagttgttct gaactcgaga aaaaacatgc cgaaatcgaa gaaaagcgtg
    26221 cagaacttga agcgaagaag caagaaatgt tgaagcgctt ggataaatag aatttagaaa
    26281 acagaaaaaa ctaaaaagaa tgtagggttt atttccctac attcttaaaa taacttagta
    26341 cataaatgac aatgctgcca ctgccgtcaa tattgcaaaa actattttcc aaattttttt
    26401 attttttcca aaaatcttat caggtaacaa gcttattaca agaaaggtaa taaacaacac
    26461 caatttaagt gtgtatatca taaaaacacc ttctttccta caattatatt ataatacttt
    26521 atgtaagcga atacaagagg tatgaggtaa tcaactacga aaaaatataa ggctgaggac
    26581 agtaaaaacc agcatttaaa gccttcactg tatctaggat ttccctattt ttagacaaga
    26641 ttgacccaaa tctacatcat taaaaaagcg aatttcaatc gaaactcgct tttttacaag
    26701 atgtattagt ataaatttgt atcttatact caatgaaaat caaagagcaa actaggaagc
    26761 tagccgcagg ttgctcaaag caccgctttg aggttgcaga taaagctgac gtggtttgaa
    26821 gagattttcg aagagtatta gttcaagtgc cagatgtctt cgttatactg agcgattgta
    26881 cggtcagatg agaagaatcc tgctttagaa atgttaacga tgactttatc caaccatgcg
    26941 tcacggtctt cgtagtcagc aagcatttgc tctttgactt tgatgtagtc ttccaagtca
    27001 agaagagtca tgaaccagtc tttgttgatc aattcattgt aaagacgttc caagcgctct
    27061 ttgtttccag ctgcaagaac tgcatcacta acgatgaagt caaccaatgg tttgatagct
    27121 tcacgagcgt agaattcgct tgatttgtaa gctgcttttg cgtaaaggtc gataacagtt
    27181 tctgaatctt caccgaagat gtagatgttt tcttctccaa ccaactcagc gatttccacg
    27241 ttagcaccgt ccatagtacc aagtgtcaaa gctccgttca acatgaattt catgttacca
    27301 gtacctgaag cttctttaga agcaagtgag atttgttctg agatatcaca tgctgggata
    27361 aggaaacttg ctgcagtaac gttgtagttt tcaaccataa ctacttgcaa gtgtggagct
    27421 actgctggat cgttagcaat aacttctgac atgcaaagga ttaaatggat aatgtcttga
    27481 gcgattgtgt aggctggagc tgctttacca ccaaagaaga ttgtgattgg acgagcaggg
    27541 atgttaccag ctttgatgtc aaggtatttg tggatcacgt acaaagcgtt catttgttgg
    27601 cgtttgtact cgtgaagacg tttgatttgg atatcaaaga tagaatttgg attgatttcc
    27661 acaccttggt gttctttcaa gtgacgagcc aatttacgtt tgttgtgagc cttgatgctt
    27721 tccaattttt ctttgacagc tgctttgtct tcataagaca aaagtttttc aagctcatct
    27781 gcttcatggt gccaaccatc tccaagaatc tcatccaagt agtgagacaa tcttgggtta
    27841 gcatgcataa gccaacgacg gaaagtgata ccgtttgttt tgttgttgaa cttttctggg
    27901 taaaggtcgt agaaggcttt caactcagaa tttttcaaga tttcagtatg aagtgctgca
    27961 accccgttaa cactgtatcc gtagtggata tccatgtgag ccatgtgaac acgtccgctc
    28021 tcatcgatga tttgaacagc tggatctttg tactctgcct tcacacgacg gtccaattct
    28081 tcgatgattg gtaccaagtg aggaaccact tcttgcaaga attcaagagg ccatttttca
    28141 agcgcctcag caaggattgt gtggttagtg taggcagtca tgctacgaac aattgagatt
    28201 gcttcgtcaa gctcgatacc acgtgcagtc aaaagacgaa tcaattcagg aatcaccatt
    28261 gatgggtgag tatcgttgat ttggacaact gcgtagtcag caaggtcatg caagttgctt
    28321 cctttttcga ttgcttcgtc gatgatcaat tgcgcaccgt ttgaaaccat gaagtattgt
    28381 tggaagatac ggagcaattc accttgacgg tcactatcat ctgggtaaag gaagagagtc
    28441 aagttgcgag cgatatctgt cttgtcaaag ttgataccat ctttaataat agaagaatca
    28501 actgaatcca agtcaaacaa acgcaagcgg tttttagtcg ctgtttcata accagtaaca
    28561 tcaatatcgt aaagagttga tgtcaaagta aagtctgcaa atggtacttg gtagctacgg
    28621 cttgagcgaa ccaaccagtt ttgctctgtc aaccatgcat ttggaattgt ttcttgttgg
    28681 ttgtttttaa gaacttgttg gaaaagacca aagtggtagt taagaccaac accgtcacca
    28741 ttcaaaccaa gagtagcaat tgagtcgata aagcaggcag ccaaacgtcc caaaccacca
    28801 ttaccaagag atggttccaa ttcaacttct tcaacttcga tcaagtcttt acctgcagct
    28861 gcaagttctt ttttaacatc gtcgtaaaga ccaaggttaa tcaagttgtt tgacaagagt
    28921 ttaccaatca agaactcagc tgagatgtag taaacttttt tcttaccagt gttgactggt
    28981 ttttggctgc ttgcaagctt gctgtagtta agaagagcaa ggtaaagctc ttcattgcta
    29041 cattctgcaa tggttttatt gtaacgattt tgtacaaatt cttgtagtga taacatgttt
    29101 agttgtctcc tgattattgt cttatttctt taaatctacc aaattttcat taattcggcg
    29161 ataaattgtt gtcaagtcaa gcaaaccttc ctcgacagct ggtgtcaatt gatcttcagt
    29221 catacgccaa gaccagtttc caccaagggt agatgggaag ttcatacgag ctgcctcatc
    29281 caattctagt aaatcttgca tagttgcaat tgccataaag ctaactgatg aaaatactgt
    29341 acgaagcata gcgtgtacca ctgtttcgta ttctttacgg ttcgtgtaac gagccatgta
    29401 ctcacgagtc gcatcatcaa tctcattacg gtaccaacca agaaccgtat tgttatcgtg
    29461 tgttcctgtg tacataactg agttagcagg tgccaagtgt gggctatcaa tgctttcgtc
    29521 ttctgggttg aaggcaaatt gaagaatctt cattcctggg aagccagtac gttcacgcaa
    29581 ttcgatcact tcatctgtca tgaagccaag gtcttctgcg atgatgttta gctcaccaag
    29641 gtcttcctta acggctgcaa aaagcttgta gcctggacct ttcacccact caccaggtgc
    29701 tgctgtatcg gaaccagcag ggatttccca gtaagattcg aagccacgga agtggtcgat
    29761 acgaacgata tcgtagattt tgaagctttc acgcaagcgt tcaatccacc atttgtagcc
    29821 gtctttgtcc attgcttccc agtcatagat tggattaccc caaagctgac cagttacaga
    29881 aaactcatct ggtgggcatc ctgcgataca agtagcctta ccattgacat ctgttttgaa
    29941 gagatgtgga tttgcccaca tatcacttga atcttccgct acgtagattg gcatgtcccc
    30001 aacgatttcg atgtggttgt cgttagcgta agctttcaat ttcaaccatt gttggaagaa
    30061 gaagtattga gtcacacggt ggtaaaccaa cttgtctgcc aattgctcac gatagctttc
    30121 aagtgctgaa gctttacgag cacgagcatc tgcatctggc cattcagtcc aagcaagatt
    30181 gtcaaaatgc tctttgatag ccatatactc agcaaagagc tcaagccatg attggttgtc
    30241 ttgagcaaat ttctcaaaat ctttaacatc tccgacttca aagaaacgtt tcaccgcttt
    30301 ttctaaaaga ggacgacgtg catagtagat tttagcatag tcaacttcag acgcatcgct
    30361 accaaagtca actccttcaa ggtcacttgc ttccaacaaa ccttgctcca ccaagatatc
    30421 taaatcgata aaatgagtgt ttcctgcgaa ggctgagaaa gattggtaag gagaatcccc
    30481 gtaactagtt gctcctaatg gaaggatttg ccagtaacgt tgttttgtac ggaccaagaa
    30541 atcaacgaag tcgtaagcac tttgaccaaa tgatccgatt ccgtaagctc ctggaagaga
    30601 agagatgtgc atcaacacac cactttgacg ttttttcata atagcacctc gtgtgttaaa
    30661 ataatggaac gttgcgtatt ttgcagacgc aaacgtttgc gttacttata agtatactcc
    30721 ttttcaagca taattgcaag cgtttttaaa aaactttttt gattattttt aaggagacta
    30781 actcatttta gcaaagataa cttaaaacta tctaatccta aggtttgact ctcacgagac
    30841 agtctacaaa gtacaaaacc tccttaggga gcttgaattt atatgtaaca aagcacaaac
    30901 gtccatagaa aatagatagg gattagaacc agggaggtag cccctcctgg tttccctctt
    30961 tagacagatt ccatatattt ttattaaaaa tactgtattc ttatctattt catacttttc
    31021 ttctattaaa atgcaaaatt atgctatcaa atcaagctta aaaatttttt aaaattttta
    31081 caaaaaatac ttgcaaccgt tttctatttg tgctatacta agctcataaa ggaaaacgtt
    31141 tgcgtttcct tatcaataaa acttgctatt ctttgggagg aatacactat gtcatctaaa
    31201 tttatgaaga gcactgcggt gcttggaact gttacacttg ctagcttgct tttggtagct
    31261 tgcggaagca aaactgctga taagcctgct gattctggtt catctgaagt caaagaactc
    31321 actgtatatg tagacgaggg atataagagc tatattgaag aggttgctaa agcttatgaa
    31381 aaagaagctg gagtaaaagt cactcttaaa actggtgatg ctctaggagg tcttgataaa
    31441 ctttctcttg acaaccaatc tggtaatgtc cctgatgtta tgatggctcc atacgaccgt
    31501 gtaggtagcc ttggttctga cggacaactt tcagaagtga aattgagcga tggtgctaaa
    31561 acagacgaca caactaaatc tcttgtaaca gctgctaatg gtaaagttta cggtgctcct
    31621 gccgttatcg agtcacttgt tatgtactac aacaaagact tggtgaaaga tgctccaaaa
    31681 acatttgctg acttggaaaa ccttgctaaa gatagcaaat acgcattcgc tggtgaagat
    31741 ggtaaaacta ctgccttcct agctgactgg acaaacttct actatacata tggacttctt
    31801 gccggtaacg gtgcttacgt ctttggccaa aacggtaaag acgctaaaga catcggtctt
    31861 gcaaacgacg gttctatcgc aggtatcaac tacgctaaat cttggtacga aaaatggcct
    31921 aaaggtatgc aagatacaga aggtgctgga aacttaatcc aaactcaatt ccaagaaggt
    31981 aaaacagctg ctatcatcga cggaccttgg aaagctcaag cctttaaaga tgctaaagta
    32041 aactacggag ttgcaactat cccaactctt ccaaatggaa aagaatatgc tgcattcggt
    32101 ggtggtaaag cttgggtcat tcctcaagcc gttaagaacc ttgaagcttc tcaaaaattt
    32161 gtagacttcc ttgttgcaac tgaacaacaa aaagtattat atgataagac taacgaaatc
    32221 ccagctaata ctgaggctcg ttcatacgct gaaggtaaaa acgatgagtt gacaacagct
    32281 gttatcaaac agttcaagaa cactcaacca ctgccaaaca tctctcaaat gtctgcagtt
    32341 tgggatccag cgaaaaatat gctctttgat gctgtaagtg gtcaaaaaga tgctaaaaca
    32401 gctgctaacg atgctgtaac attgatcaaa gaaacaatca aacaaaaatt tggtgaataa
    32461 aaaatttgtt caaggggggt ggaaatcaaa tccccctttg aatttatcaa tagagacaca
    32521 aataatttag ctttcttata aaaaagtagt atcctatgaa aggagttaat atggaaaagc
    32581 aacaacctag taaagcagcc ctgctgtcta tcattcctgg gttaggacag atttacaata
    32641 aacaaaaagc caaaggtttt atcttcctta gtgtaaccat cgtatttgtc ctttacttcc
    32701 tagcacttgc aacccctgaa ttgagcaacc tcatcactct tggtgacaaa ccaggtcgtg
    32761 ataattccct ctttatgctg attcgtggtg ccttccatct aatctttgta atcgtttatg
    32821 tactctttta tttctcaaat atcaaagatg cacatacgat tgcaaaacgc attaacaatg
    32881 gaattccagt tccacgcaca ctcaaagaca tgatcaaagg gatttatgaa aatggcttcc
    32941 cttacctctt gatcattcca tcttatgttg ccatgacctt cgcgattatc ttcccagtta
    33001 tcgtaacctt gatgatcgcc tttaccaact acgacttcca acacttgcca ccaaacaagt
    33061 tgttggactg ggttggtttg accaacttta caaacatttg gagcttgagt accttccgtt
    33121 ctgcctttgg ttctgttctt tcttggacta tcatttgggc tttggcagct tctactttac
    33181 aaatcgtaat tggtatcttc acagctatca ttgccaacca accatttatc aaaggaaaac
    33241 gtatctttgg tgttattttc cttcttcctt gggctgtccc agccttcatc actatcttga
    33301 cattctcaaa catgtttaac gatagtgtcg gtgctatcaa cactcaagta ttgccaatct
    33361 tggctaaatt ccttcctttc cttgatggag ctcttattcc ttggaaaaca gacccaactt
    33421 ggacgaagat tgccttgatt atgatgcaag gttggctcgg attcccatac atctacgttt
    33481 tgactttggg tatcttgcaa tctattccta acgaccttta cgaagcagct tatattgacg
    33541 gtgccaacgc ttggcaaaaa ttccgcaaca tcactttccc aatgattttg gctgttgcgg
    33601 cacctacttt gattagccaa tacaccttca actttaacaa cttctctatc atgtacctct
    33661 tcaatggtgg aggacctggt agtgtcggag gtggagctgg ttcaaccgat atcttgatct
    33721 catggatcta ccgtttgaca acaggtacat ctcctcaata ctcaatggcg gcagctgtta
    33781 ccttgattat ctctatcatt gtcatctcaa tctctatgat cgcattcaag aaactacacg
    33841 catttgatat ggaggacgtc taagatgaat aactcaatta aactcaaacg tagactgact
    33901 caaagcctta cttaccttta cctgattggt ctatcaattg taattatcta tccactgttg
    33961 attaccatca tgtcagcctt taaagcaggt aacgtctcag cctttaaact agatactaat
    34021 atcgacctca attttgataa ctttaaaggc ctcttcactg aaaccttgta cggtacttgg
    34081 tacctcaaca ctttgattat cgccttaatt accatggctg ttcaaacaag tatcatcgta
    34141 cttgctggtt atgcttacag ccgttacaac ttcttggctc gtaaacaaag tttggtcttc
    34201 ttcttgatca tccaaatggt gccaactatg gccgctttga cagccttctt cgttatggcg
    34261 cttatgttga acgcccttaa ccacaactgg ttcctcatct tcctctacgt tggtggtggt
    34321 atcccgatga atgcttggct catgaaaggc tacttcgata cagtgccaat gtctttagac
    34381 gaatctgcaa aactagacgg tgcaggacac ttccgccgct tctggcaaat tgttctacca
    34441 cttgttcgcc caatggttgc cgtacaagct ctctgggcct tcatgggacc tttcggggac
    34501 tacatcctct ctagtttctt gcttcgtgag aaagaatact ttactgttgc cgtaggtctc
    34561 caaaccttcg ttaacaatgc gaaaaacttg aagattgcct acttctcagc aggtgctatc
    34621 ctcatcgccc ttccaatctg tattctcttc ttcttcctac aaaagaactt tgtttcagga
    34681 cttacaagtg gtggcgacaa gggataattt atccccgcca ccctttttca ttttatactc
    34741 ttcgaaaatc tcttcaagcc acgtcagctt tatctccaac ctcaaagttg tgctttgagc
    34801 aacctgcagc tagcttcctg gtttgcactt tgattttcat tgactattag cgattgtcac
    34861 tgtaaataat atccttgtag caagcaattt accccctaga cttgaaataa agcgcatttc
    34921 tctatataat aatactcata tagaaaacac cttttagaaa gatacctatg cttccatatc
    34981 cattttccta tttttcaagt atttgggggt ttcgtaagcc cctgtccaaa cgtttcgagc
    35041 tcaactggtt tcaacttctc tttaccagta tcttccttat cagcttgtct atggtaccca
    35101 ttgctatcca aaacagctcc caggagacct atccgctaga aacttttatc gataatgtct
    35161 atgaacctct gacaaatgag gttgtccagg atctctctga acatgctaca attgtcgatg
    35221 gcacattaac ttatactgga acagctagtc aagccccttc tgttgtgatt ggtccaggtc
    35281 aaatcaagga attacctaag gacttgcaac tgcatttcga tacaaatgaa ctagtcatca
    35341 gcaaggaaag caaggaactg acccgcatct cttaccgagc cattcagact gagagtttca
    35401 aaagcaaaga cagcttgacc caagcaattt ctaaagactg gtaccaacaa aatcgtgtct
    35461 atatcagcct cttcctagtt ctcggtgcga gcttcctctt tggtttgaat ttctttatcg
    35521 tctctctagg agctagtctt ctcctttata tcactaagaa atcacgcctc ttttcattta
    35581 gaacctttaa agagtgctat cactttatct tgaactgttt aggattgccg actctgatta
    35641 cacttatttt gggattattt ggccaaaata tgacaaccct gattactgta caaaatattc
    35701 tttttgttct gtatctggtc actatctttt ataaaacaca tttccgtgat ccaaattacc
    35761 ataaatagga gatttttatg cccgttacga ttaaagacgt ggccaaggct gctggtgttt
    35821 cgccttcaac cgtaacccgt gttattcaaa ataaatcaac cattagcgac gaaacaaaaa
    35881 aacgcgttcg caaagctatg aaggaactca actaccaccc aaaccttaac gctcgtagct
    35941 tggtaagcag ctatactcag gttatcggat tagttcttcc tgatgactca gacgccttct
    36001 accagaatcc tttctttcca tcggttctac gtggcatctc tcaagtcgca tctgaaaacc
    36061 actatgccat tcaaatagca acagggaaag atgagaagga gcgtctcaac gctatttcac
    36121 aaatggtcta cggcaagcgt gtagatgggc taatctttct ctatgcccaa gaagaagacc
    36181 ctctcgtaaa actcgtcgca gaagaacagt tccccttcct tatcttaggt aaatctctat
    36241 ctcctttcat cccacttgtc gacaacgaca atgttcaagc tggttttgat gcgactgaat
    36301 atttcatcaa aaaaggctgc aaacgcattg cctttatcgg aggaagtaaa aagctcttcg
    36361 tgaccaaaga ccgtttaacg ggctatgaac aggcgcttaa acattacaaa cttaccactg
    36421 acaacaatcg catctacttt gccgacgagt ttctggaaga aaagggctat aaatttagca
    36481 agcgattatt caagcacgat ccacaaattg atgctatcat cacaaccgat agcctcctag
    36541 ctgaaggtgt ttgtaactat attgccaaac accagctgga tgtccctgtt ctcagctttg
    36601 actcggttaa tcccaagctc aacttggcag cctatgtcga tatcaatagt ttagagcttg
    36661 gtcgtgtttc ccttgaaact attctccaga ttattaatga taataaaaac aataaacaaa
    36721 tttgttaccg tcaattgatc gcccacaaaa ttatcgaaaa ataagagact gggcaaaaag
    36781 tcgttaaaag caaaaacgca tactatcagg tattgaaaaa acttgatact atgcgtttta
    36841 ttgtgggaag atttacttcc ttttcttctg aaattgagtt gttacccaag atctttttat
    36901 actcaataaa aatcaaagtg caaactagga agctagccgc aggttgctca aaacactgtt
    36961 ttgaggttgt ggatagaact gacgaagtca gctcaaaaca tggttttgag gttgcagata
    37021 gaactgacga agtcagtaac atacctacgg caaggcgacg ctgacgtggt ttgaagagat
    37081 tttcgaagag tattaatcac taattatcta tctcaacaaa tcttcctaga atatgaacat
    37141 tttccgagac agagacaaag gagcttggat ccacttgtgt cataatctgt ttaaattcat
    37201 taaactctgc acgtgtaatg acagtgatta aaactgcctt tctctcgtga ttataggttc
    37261 cttctgcatc gtggatcatg gttgctccgc ggtgcaattt tttatggatt ttttcaatta
    37321 ccttctctgg atgatttgtc acaatcatgg cctgcatacg cttttgctta gtaaagactg
    37381 cgtctgtcac acggctagag acaaagatgg taatcataga ataaagagcg tatttccaac
    37441 caaaggtcaa acctgctatc agcatgatag ttccatttac caagaaagaa atactaccga
    37501 cattcttacc cgttttcttg cgaatagtca ggctgacgat atccgtccca ccactggaga
    37561 tattgtttcg aagagcaaaa ccaatcccca aacccataac aacaccccca aaaagggaat
    37621 tgataatggg atcctccgtc aaggttgcca cagggacaaa ctggataaag aaggaactca
    37681 tagataccgt gataaaggta aagacggtga acttatggcc aatctgatac caagctaaga
    37741 ccatcaaagg gaagttaatg gcgtagaagc ttagcgaaat cggaatatga aaaccaaacc
    37801 agtgattact caaggcagag ataatctgtg ccagacctgt tgcaccactc gaatacacat
    37861 gccctggttg gaaaaagaaa ttaactgcta ctgctgataa aaaaccatag accagagagg
    37921 ccgaaatctt ctcatcatac ttttctcgag agatactttg taagacacgt aaaattttta
    37981 tctgataagc aaagcggcgc agataatagc gccaccgctt aattcgtttt gtttgtttca
    38041 tcttcttcta cttgtaagct gagttcctct agttgtttga gagcgactgt tgatggagct
    38101 tgtgtcattg gatcagttgc cttgttgttc ttaggaaagg caatgacttc acggatattt
    38161 tcttctccag caagcaacat gacaaaacgg tcaagcccga tagccaaacc accgtgtggt
    38221 gggaaaccat agtccatggc ttcaagaagg aaaccaaact ggtcattggc ttcttcagct
    38281 gagaaaccaa gagccttgaa catgcgttct tgaaggtctt tttggttgat acgaaggcta
    38341 ccaccaccaa gctcataacc gttcaagacg atatcgtaag caatggcacg aaccttagcc
    38401 aaatcacctt ctaattcgtg agcagtctct tcctgtggaa gtgtgaatgg atggtgggcg
    38461 ctcatgtagc ggccttcttc ttcagaccat tcaaacatcg gccagtcaac cacccaaagg
    38521 aagttgaact tatcattatc aatcaagcca agctctttag caatacgtcc acgaagggca
    38581 cccagtgttg cattagccac ttcaagcgta tccgccacaa agagaaccaa gtccttatct
    38641 tcaagagcaa gcgctgttgt caattcttct tggataccag tcaagaactt ggcaactggt
    38701 ccgtttaatt ctccatcaac caccttgacc caagcaagac ctttggcacc atactgtttg
    38761 gctacttccg tcatcttgtc gatgtcttta cgtgaatagt tgtccgcagc tcctttgacc
    38821 acaatcgctt ttacagcaag tgcttctgaa aagactttaa agtctacacc tttgaccact
    38881 tctgtcaagt cctgaagcaa catgtcaaaa cgagtatctg gcttgtcaga accgtaaaga
    38941 gccatagcat catcgtattt catatgaggg aacggtagcg ttacttcgat gccttttgtt
    39001 tccttcatca cgcgcgcgat caagccttct gtaatatctt ggatttcttg ctcagtaagg
    39061 aaggacgttt ccaagtcgac ctgagtaaat tcaggctggc ggtctccacg caagtcctcg
    39121 tcacggaaac atttaacgat ttggtagtaa cggtcaaaac cagcattcat caagagctgt
    39181 ttcgtgattt gtggactttg aggaagagcg taaaaatgcc ccttattaac acgagacggc
    39241 actaaataat cacgcgcccc ttcaggcgtt gacttagaaa ggaatggtgt ctccacgtcg
    39301 ataaactcca actcatctaa gtagttgcgg atagagtggg tcaccttggc acgaagttta
    39361 agattttcca acatttctgg acgacgaagg tcaaggtaac ggtaacgcaa acgtgtatcg
    39421 tcatttgcct caatgccatc cttaatctca aatggtgttg tcttagctgt gttaagcaca
    39481 ataagagctg tcacgtttaa ctcaaccgca ccagttggca acttatcatt ggcttgctca
    39541 cgcgcagcga cctgaccagt cacctcaata acaaattcgc tacgaaggct ttcagctgtt
    39601 gccataacct ctgcagatac tttttcaggg ttgataacca actgcatgat tccttcacgg
    39661 tcacgaagat cgataaagat caaaccacca aggtcacgac gacggccaac ccatcctttc
    39721 aaggttattt cttgtccgat gtgttcctca cgaacacgac cagcatacat actacgtttc
    39781 attatttctc tcctctttta ttctgttact attttaccat aaaagcgcag gctcttcatg
    39841 aaaatcatca gaaaagtttg ccagtcttta aaagtcaggt gaaagcccta aaaattagcg
    39901 ctaatgctct tcgaaaatct cttcaaacca cgtcagcgtc gccttaccgt aggtatggtt
    39961 actgacttcg tcagtttcat ctacaacctc aaaaccatgt tttgagctga cttcgtcagt
    40021 ttcatctaca acctcaaaac catgttttga gctgacttcg tcagtttcat ccacaacctc
    40081 aaaacagtgt tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
    40141 gtataataca aaaatccgat gaacttcacc ggactctttt attttgaatt tttgcctgct
    40201 ttacgctttt cagcgatttc ggctgccttt cgaggcaaga caatttccgt tatgtaagcc
    40261 gtcccaaaac gcagtacacc tgcaatagga gcaaagacaa ctgctagata gttatagaag
    40321 aaatcgcctt tgaaggcata agctagcgct ccaatgatga aaaatagaac gactgcctga
    40381 atcactgcta ataaaattac tcgtttcatg tgacctcctg actctattat agcatgagaa
    40441 tcatcaaaaa gccgactaaa ttattcaaag cgtgaagaga aatactgtag accagacctt
    40501 ttctgctaat gtaagccaaa cccaaactaa aaccaaggct aaaatagaca aaaaattgtt
    40561 gcacatcacc tggaaaatga atcaaggcaa atagaagact agataccaga agaaaaatca
    40621 gggttcgttt actattgtcc tgcttaggaa agagatagcg tgctaacatc cctctaaaaa
    40681 caatctcttc cgtcaaagga gcaaaaataa ccacagcaaa gaatgagaaa agtggttgag
    40741 acaaggtcaa gtctgtcgct atttgttgat ttactgaagg atcatctagc aagaagaatt
    40801 gaacgaccag agataagaac caaaccaagg caggaagcca aataaatcgg ttaaagccgc
    40861 tcttctcaat ataaacagga gctttctgat accatttgta aatgccgtac acatatactc
    40921 cagccaagac cacatagagt agagtaacag catagggtga agcgcctaaa gcaagcgacg
    40981 cagtcgcgag cccctgaata aagccataga taaagaaaaa ggatagaagg gctagaagaa
    41041 accagccaag gtttttaagt agtttcatag ataactcctt tatttgaaat aacgttttac
    41101 cataggtaac tgcatcacat tgatataaac atggatggct cctacaagca agaaagctag
    41161 taactgaatc tctcctgtca agaaagaaat gataataaga aaaatatata aggctggtaa
    41221 gacatattgg tgtaattgga ataaaattcg aaaactctgt tccaaattag cctgacgctc
    41281 cccttcatca taagaattta tatagttcaa gacatccttt ggtgtagcga aaaattccaa
    41341 atcaaactga cgaacaatcg caatggtttt aaaaagagat ttttgagcga ctaagaatac
    41401 cacaaagagt aagaaagaaa ggaaaaatgt ttgagggttt gtatgcaata taatcacctc
    41461 acttaatgaa ataaaaatag ccaatggaat cgctacacct gtaatattaa aagcaatggt
    41521 tccaaactca agattccgat acatttgcac ataataggtt tcattcagat cgtcatccat
    41581 ttcctcttga tacaaggaat gaaattttct gcttttcttt aagaaattga aagtcaaaaa
    41641 catactaatg aaacctatca gtaaacaaat agctgatatc catggcatca aggcttttac
    41701 atctaaaata atttcgtggg attcgacacg tgccttaaac atccctacaa acatgcccaa
    41761 gaaccccccc aagacaatag acatcaaaaa taacaatcta cgtttctttt tcatattcat
    41821 tctccttttt cacttgctag atttttggat ttcttttcaa tccattcaat tactgggatg
    41881 agagcaaagt agacccaaac aaattggtcg ctttgatagg gattaaacca gcttaggtcc
    41941 atcccaatca gtagaaatac actgactaat aaagctatga ccactacata ataaatcact
    42001 ttatacttgt tcatcactcg tcctcctcca aacgaaatac cgattcgact gtttcgttga
    42061 aaatttgaga tattttcagg gcaatgataa tggatggggt gtactcatcc cgttctagta
    42121 ggctaatggt ctgtctggaa acccctgcca gtttggctag gtcggtttga ttgagaccat
    42181 cgcgagctcg aagctctttt agacgatttt ttagttgcat gttacacacc tactctccgt
    42241 caaattcaac ggtttggata tcttcaatac gttgcaactt gaatttttct ttcccctttt
    42301 tatcaacact acgtagtttg acccattcct catcaacatc cacaacttcc cagttatctg
    42361 gcccaatata cactcccgtt ataattggtt cctttccaat catttcttgt aataatctcg
    42421 acatttctgc gtttcctttc tcttttcgct caagtttttt gattttattc tctagtttct
    42481 tgattttttt agaattatta gaataaaaga aaatcataaa tagtataaat actagtaccc
    42541 acattataac tcctttctgc ttcctatttc ttaacttgaa ttcattgtaa cacatctttt
    42601 tctttttgat aaatatattt gtcaaaaagt ttatgatttt tgtcattttg caaaagaaaa
    42661 aggtcaggag taagttcctg accactttat ctatcattaa tactcttcta aaatctcttc
    42721 aaaccacgtc agcttcacct tgccgtaggt atggttactg acttcgtcag tttcatctac
    42781 aacctcaaaa ccatgttttg agctgacttc gtcagttcta tccacaacct caaaacagtg
    42841 ttttgagcaa cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaaat
    42901 cctagttttt caaagatttc tgagaagttt tggctgattg tctcaagtga cacttgcact
    42961 tcttctcggg tttggttgtt cttgactgtc acttgtctgc tttcgacttc gctctctcct
    43021 agggtgatga gggtcttagc tgcaaagaca tcggctgact tgaattgagc tttgagttta
    43081 cggttgaggt aatcacgctc tgctttgaaa ccttgttggc gaagggcttg gactagttct
    43141 agggctttga catttgctcc atcacccaag actgcgatat agacatctag ggcattttcg
    43201 atagggaggg ccacgccttg tttttcaagg atgagaagca ggcgctctac accaagccca
    43261 aaaccaaatc cagcagtttc agggcctcca aagtaagcaa ccaaaccatc gtagcgacca
    43321 cccgcacaga ctgtcaagtc attgccctca atctctgtga taaactcgaa aatggtgtgg
    43381 ttgtagtagt ccagaccacg caccatattg gtatcgatga tgtaatctac tccaagattt
    43441 tccaacatct gactcacagc atcaaaatga gtttggcttt cttcatcaag aaagtccaag
    43501 atagacggcg cattctctac tgccaccttg tcttcttttt ccttagagtc caagacacga
    43561 agaggatttt cctccaagcg acgttggcta tccttagaca aggtctcctt gagcggtgtc
    43621 aaatagtcaa tcaaggcttg gcggtaggct gcacggctct caggatttcc aagagtgttg
    43681 aggtgcaatt tgacaccttg aataccgatt tccttcaaaa aatgggctgc cataacgatt
    43741 gtttccacat cggtagctgg attgctagaa ccaaaacact caacaccaat ctggtggaat
    43801 tggcgcaagc gccctgcctg tggacgctca taacggaaca taggtcccat gtagtagaac
    43861 ttgcttggct tttgcacttc tggggcgaag agtttatttt ccacatagga acggacaacg
    43921 ggcgcagttc cttctggacg gagggtaata tgacggtcac ccttgtcata aaaatcgtac
    43981 atttccttgg ttacgatatc cgttgtatct ccgacagagc gactgataac ctcgtaatgc
    44041 tcaaaaatag gcgtgcgcac ttctgcatag ttatagcgct tgaaaatctc acgggcaaag
    44101 ccctcaacgt actgccactt agcagattca gcaggtaaaa tatcctgcgt tccttttggt
    44161 ttttgtaatt tcatagggaa tcctctttaa acttaatagt cttattttac cacaaataaa
    44221 gggattaaaa cagtaagaaa aaaattagga tttagatatc atttttgaga ttaagaattg
    44281 tcaaaaaaat agctagcaag gaaagaccaa caaatagcat ccaagtcaac tgtatattcc
    44341 atacggctac tagtgaaaaa caagctgttc ccacaggtat ggataaggta aacaatagac
    44401 ctaaaaaatt actagtacga gctagaacct ctggagctag atttttcatg agcatggcac
    44461 taatctttgg ttgaacttta ccagacacat acagggtaaa gaagagaaat agcaaaccaa
    44521 gcacgacttg attgaataaa ttagccaaac caactagact aagtcctacg gtcgcccaca
    44581 tcatcaatct aggcaaggac tgcttcccaa aataatcatt gcccgtaagg ctactgatga
    44641 tgactgctac taaaacacag aattgattga taaatagtgc ctctgtataa gaaaaattca
    44701 agagagaatg gctcaaaaag aagatattat aaattccacc caaagcgcca cccaaggaat
    44761 taataagcaa gacagcaaag agcataaaac caaagttttt ctgtccactt ttaagaaaaa
    44821 cgagacgtaa atttcggtaa attgttagga actggtcttt gatagaaagc ttctcatttt
    44881 ttaagttttc accatcagca gatgacattg acaggctcaa tttgcttttt cctaaaaaga
    44941 ggatagtggc tgatactagg aaaaagcagg cattgattcc cgcaacgaga gaaaaattgt
    45001 tgaccgatag agctaagagc cagactccga aagcttgacc accaatagct gaaatatagg
    45061 tgatgaactg tgaaaaagaa taagcctcca tcagatcatc ttcagctact ttttccttaa
    45121 taagaggcat acgcaggcca cctgcaaaat cactgatgat atcactaatg acattgatca
    45181 aacacaggct agaaaaggca aagagactag cttgctgaac aactagggct gctagaaaaa
    45241 atagaaccgc ctgaaacaaa ccgctataga ccatccattt gaccttgtcc ctcgtgtaat
    45301 ctgcccgaat ccctacaaaa actgtaaaga gggtcggaag aatcatgaca atattcgcca
    45361 tagcaacagc aaaagatgct tgtgacaagg tcgatgcata gacgataaag accaggttga
    45421 aaatcgaagc accaaaagca ttgaagaagc atgataaagt caaaattcta taagctggat
    45481 ttctaaacaa tagtttcata gataatctcc cttcttgttc gaacctctat atgaagtatg
    45541 actatagtat agcacttaga aatttgagag ggagaactct tgaatatatg caacaaataa
    45601 aatgagcaaa aagaaacgat agaacttttg taatgacctg agagagggca atagttctat
    45661 cgcttcaaat tttttcttgg tttgcagata ttcaacattc ggtcgtattt ctatagtatt
    45721 cggcagattt attacagcca agcatctcaa aaatacggac agcatcctcc atctttttct
    45781 ggccttcctt gactctacct tgcttgctat caaggagacc ttctgcccac agataaacaa
    45841 ttcggaaata ggtctcattt tccttgtaga aatgctcttc gataacacgt ttaaaataat
    45901 aggcattggt aaattcttca cactcaatac tagctaaaaa gccattcaat agtatagtat
    45961 gaaaaaagtt tcgattacca gacatttcca ttagaaaatc agatttacgt accatttctc
    46021 gtacatatct agtaaaaaga gaaacagata aaaaggcaga actgactgaa aataaattga
    46081 gttcatagat tccccagatc tcggtagaaa acaaataatc atgaaggact tttccttcct
    46141 ctgctgttaa ctctaccctt tcatccatgc tcttcatata agacttgatc ataatggcat
    46201 ttagaatatg tttctgtttg ttgtgagaat gggcatgctt ttgatactcc ctgcgatata
    46261 agtcctcaag aggtgctata ttctttggtt ccaagacatc tgtaatttct tttctcaact
    46321 cagaatctgt atcatactgg aaacctctcg ccagaaagag gatctcctcc acactggcag
    46381 atatattttc cagagcaaat agaaactttt ccaccgaaag ctcactctga cctgtttcaa
    46441 aacgggacaa catagacggc gaaaattgtc ctccggttgc ttgtctcagt gagatatttc
    46501 ttgattctcg taattgtcta aagacttttc caatctgctc catagacttc cccttgattc
    46561 cgtattttct tcattttatc atatttttca gaaaattcat caaaaacttg ccaaattgtc
    46621 agaattatga gaaaatagag gatatttatc acgtggaggg actgctatga gagacgatat
    46681 caaaatcaat gaccgtgctt tggccttgca agaccaaatt atcgaaaaac tagagaaagt
    46741 ttttgataca gatgtggaat tggatgttta caatctaggt ctgatttatg aaatcaatct
    46801 ggatgaaacg gggctctgca agattgtcat gaccttcacc gatactgcct gtgattgcgc
    46861 cgaaagcctg cctattgaaa tcgtggcagg tctgaaacaa atcgagggta tcaaagatat
    46921 caaggttgaa gttacctggt cgcctgcctg gaaaatcaca cgaatcagtc gctatggccg
    46981 tattgccctt ggactaccac ctcgttaagc aggccaatca cttttaaaga tgaaaaaagc
    47041 aagccgaaaa tggcttgctt tttgatactc aatgaaaatc aaagggcaaa ctagaaaact
    47101 agccgcaggt tgctcaaaac actgttttga agttatggat agaactgacg aagtcagctc
    47161 aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata cctacggcaa
    47221 ggcgacgttg acgtgatttg aagagatttt cgagtatgag tttatttttt acctgacttg
    47281 tccatattcc agaagtctgt cacggctccg cgtgaagcag atgatacgat gtgggcatat
    47341 ttaccgagga caccacggct gtaaagtggt ggcaaggttg tttctgcctt gcgtttttca
    47401 agttcttctt cggatacggc catggaaatt tctttggtat cttggtcaac cgtaacgata
    47461 tcgccggtac ggagataggc aattggtcca ccatcctgag cttcaggagc gatatgtcca
    47521 acaaccagac cataagtacc accagagaaa cgtccgtccg tcaagagggc caccttatct
    47581 ccctgacctt taccaacaat cattgatgaa agtgacagca tctcaggcat accaggacca
    47641 cctttaggtc caacaaaacg aacaacgact acatcgccat caacgatttc atctgtcaga
    47701 acggcctgaa tcgcatcttc ttctgagtca aagaccttag ctggcccaac gtgacgacgc
    47761 actttaacac ctgatacctt ggcaactgca ccgtcaggag caaggttccc gttcaagatg
    47821 ataagcggac catccgcacg ttttggattt tcaagtggca tgataacttt ttggcctgga
    47881 gtcaagtctg caaagtcagc caagttttca gctacagtct taccagtaca tgtgatgcga
    47941 tctccgtgaa ggaaaccatt tgccaacaag tacttcataa ccgcagggac accaccgact
    48001 tcgtagaggt cttggaagac atactgacca gatggtttca agtcggccaa gtgaggcaca
    48061 cgttcttgaa tcgtattgaa gtcctcaagt gacaagtcaa catttgcggc atgggcaatg
    48121 gcgagcaagt gaagagtggc gtttgtagaa ccaccgagag ccatcgttac agtaatagca
    48181 tcttcaaagg cttcacgagt caagatatct gatggtttga gaccaagttc caacatctta
    48241 acaacagcac gtcctgctgc ttcgatatct tctttcttat cagctgattc agctgggtga
    48301 gaggatgacc ctggcaaact catccctaga acttcgatag cagttgccat ggtattagca
    48361 gtatacatac caccacaacc accagggcca gggcaggcat tacattcaag acgtttcacg
    48421 tcctcagctg tcatgtcacc gtggttccat tttccgatac cttcaaagac agaaaccaag
    48481 tcgatatctt taccatcaag atttcccggt gcaatagttc caccataggc gaaaatagct
    48541 gggatatcca tattagcaat agcaatcata gatccaggca tgttcttgtc acagccaccg
    48601 atagcgacga aggcatccac gttgtgacca ctcatagccg cctcgatgga gtccgcgatg
    48661 atgtcacgag atgttagaga gaaacgcata ccaggcgttc ccatagcgat cccgtccgct
    48721 acggtaatgg ttccaaactg tacaggccaa gcgcctgcag atttgacacc ttctttagcc
    48781 agtttcccga aatcatgcaa gtgaatgtta catggtgtat tttccgccca agtcgaaatc
    48841 actcccacaa tcgatgtttc aaagtcctta tctgtcatac cagtcgcacg aagcatagca
    48901 cggttaggtg atttaaccat gctgtcatag atgctactgc ggtgacgttt atctaattca
    48961 gtcatcttat ccctcccatt tcagttttta ctattatagc acaatttaaa ggcaatgaac
    49021 agaataaaat tcttgaattt tcagaaaatt ctatacgcat gtgaaatatt taaaattaaa
    49081 aacaacaaag cggattagtg cactttctga tgaccagaat atgcttttta atccgctttc
    49141 tttaaataac gtaatgtaat ttttacagaa attctttcag ataagtgtat ttaacatcta
    49201 tcttgcatta taaatttcta gaaccttctc ttttatattc gattcactca aaccatactc
    49261 attaagaaga taatccattt tccctacttg accaaatctt tcttgaacac ccatccgatg
    49321 aatttttgtt attccatcat cagagaataa ttcacataaa gcactgccaa ttccacctat
    49381 ctgattgtgg ttttctacag taaatatagt ttttccactt aacattgttt ttatctgttc
    49441 tggtatcggt ttgattctaa ataaatctat cacacctact gaataaccta atttagacag
    49501 ttcatctgca actcgaatac ttggagcaac cattatacca gaagcaacga ttacaagatc
    49561 ttcaccatgc cttaactcaa tgtagccttt agaaaaatct tctccacctt gatacacagg
    49621 aactggagct tttctaattg ttcgaatata ttttagtcct tttaagtcta atgtctggtt
    49681 caatatttca cgaaattgga tatcatcagt tgcttcaaaa atgatcgatt taggaattaa
    49741 acgtaacaat ccaatttctt caaatggcat atgtgtccca ccattcattt ctgcagttac
    49801 tcctgcatct gatccaatca cagtggcatc caattgtgcg tatccaagag aaataaataa
    49861 ttgatcaaat actcttcgtg aagcaaaagg accaaatgta tgaagataag gtctaaaccc
    49921 ctgaatagac aagcctgctg caaggccgac catttctgct tccataatcc caacattcac
    49981 ataacggtct ccaaagtcct tttcaagatt attagtagcc atcgaacttg acaaatcggc
    50041 ttctaagact actatatcag aataactttg attagcctct aaaaggaagt ctctatatac
    50101 atgccgtaat tctttcgtgc ttctcatcat tctgtttcct ccaattcctg acttaatctt
    50161 tctacaactg aagttaacat ttgtctctcc tctacagtag ggcgaagatg atggttggat
    50221 ttcatttctt ccagctcttg aaccccttga cctttaatag tatctaatac aatgcactta
    50281 ggtgatgaat tatttgactg ttttaattgg acaatccctt cataaatttc tctaatatct
    50341 gaacccttga ccctaatgga ttcaaatcca aatgctgaaa atttttctac gaaatcacct
    50401 ggattacaaa tatcctttgt aaaaccatct aattgttttt tgttatcatc aacaaataca
    50461 attaagttgg ataactgttg atgagaagca aactgtatag cctcccaaca ttgtccctca
    50521 tttaactcac catctccaac aatagcataa gtataaaagg gactctttct tattctctga
    50581 ccatatgcaa gtccagttgc aacactaatt ccttgtccta aagagcccgt tgtcatatct
    50641 atgcctggcg ttagatttct atcaggatga gacggtaatt tggttccatt tgtatttaaa
    50701 gaatatagga attctttgtc aaagaaacca ttcaaataga gtgtactgta tagagctggt
    50761 cctccatgac cttttgataa tatgaaataa tctctatctc gtgctgcaaa tatttctgga
    50821 gtcattggca ttatttcacc ataaagcact gctaaaactt ctacgataga cagacttcct
    50881 ccgtaatgtc cgaatccaag atgattcaat gttctaagag tatttaatcg gatgttagtc
    50941 gcaaattttc ttaacccatc ttctctattt ttacttaaaa tcatccctta ttcctccttt
    51001 gcagatggct ttttaataaa ggatactcca aacataactg ctagaataag aacaagacca
    51061 atcacaatgc ctgcttgtga accaaattga tttaacattc ctaaaataat tcctgataga
    51121 ccaaaatctg catctgagaa agttgatcct tggaaaccaa gtcctcccaa aactggcatt
    51181 aaaaagactg gaagaaaact gattaaaata ccttgtaaaa atgctccaat agtggctcca
    51241 cgaacaccac cagatgcatt cccaatgaca cctgcagtcg ctccacagaa gaaatgaggt
    51301 acaacgcctg gtaagataac aaccgttcct gaagcaatca taattaccat acttactaaa
    51361 ccaccaacaa aactagagat aaatccaatt agaactgcat tgggtgcata agtataaaca
    51421 atcggacaat ccaaagcagg tttggaatta ggtacaagac gctctgaaat acctttaaag
    51481 gctggaacaa tttcgcccaa aataaggcga acacctgcta aaataacaaa tacccctgct
    51541 gcaaattgac ctgctaattg taaagcataa actagaccac ttgtaccact actgatttct
    51601 ttttctatat attctgaccc tgcaaagata gctacaataa tgtaaataac tgccatggat
    51661 aaagtaatac taacagtact atcacgtaaa aaagctaaac tctttggaaa tttaatgtcc
    51721 tctgttgatt ttgatttgtc accgataagg ctaccagtaa aaccactcaa ccaatatccc
    51781 aaagaactga aatgacctaa agccaccttg tcatttccag ttaattgaac catatatttt
    51841 tgaacaaatg ctggggaaat actcataata ataccgagtg ctaatcctcc tagtaagatg
    51901 agaggcaagc tagtaaagcc agcaactgat aaaatgaccg caatcataca tgccatatat
    51961 agagtgtggt gccctgttaa aaaaatatat ttaaatcgag taaaacgagc gattaagata
    52021 ttgaacacca tgcctgcaaa cataatcatt gcagtagctg agccatatgt tgttaaagct
    52081 acagctacaa ttgcttcatt attcggcaca acgccagata aatgaaaagc atgctcaaac
    52141 atggtaccaa atggatttaa agaattttgt acaattcctg caccaccaga tacaactaag
    52201 aaaccaacaa aggtcttaat tccaccttta ataatatcag gtaatttctt cttctgaaga
    52261 actaatccta agattgcaat taaagctact aaaatagctg gtgtactaac aatatccaat
    52321 atgaacttca tcatgacgct agcctcctat ataagtcctt tttcttcaca aattttagta
    52381 attaattctc gtagttcgtc catatcaata atactattta agatacgaac atctccaaga
    52441 tgactagctg aatcagctag atcacgacca acaatccaaa tatcagctgc atttggatct
    52501 gctccaccta aatcataatg ttcaacttct acatccgaaa cattcaaatc actcaataca
    52561 gattcaatat tcatctgtac cataaaactt gaacctaatc ctgaaccaca agctgtacca
    52621 atttttaaca ttatctaatc ctcctgttta attatcattt taatatcatt atagtttttt
    52681 gatgatatta aagtttgaac atgattttta tctcttaaaa ttgttgttaa atgtgacaaa
    52741 gcctttaaat gactctcatt atcaatggct gcaatacaaa tcaacaatct tacctcttgt
    52801 tctggattat ccaataaata aatcggttct tccaaaacta acattgacat tcctatttca
    52861 ttcacacctt catctggccg agcgtgagga attgctactc ccttccctaa attaataaaa
    52921 ggtccaaact cttctacttt ttgaatcatt gcctcagggt agttctcagt tatcttatct
    52981 tgatccaaaa gcggtttagc tgctaaacga atcgcctcct tccatcctaa tttttgcgaa
    53041 ctaacctgat aggtttcttt ggtaataagt tgttctagca ctggtacaat ttcctttcta
    53101 tcattttttt gataaagata attctttaac gccaatctta attccaattc ttgtgtaata
    53161 attccatatc ttttgacaat attcaggatt tgttcaatct caaaatctcc atactctaaa
    53221 ttcggaaaat cttttaacac tagttctact agttgtattg cttgctcttc agtcatcata
    53281 accgaaacta gataatttgg cttttctgtc tccaccttta tggtagaaaa aaccatatca
    53341 tagtcactac taactttcac ctgtaaatca tcaatctttg aggttcctat aaactcaatt
    53401 tgaggaaata atgctaatag attctctttt aacatcaatg aagaactaac accattagga
    53461 caaatgattg ctgctttata gcatttttga ggcaaagtat ctgctttctt taaataacct
    53521 ccgaaatgga taacaaaata tgctgtttca ctatcaggta tgggattgtc aatagcgtcc
    53581 atcaagggca tcaaagaatc tttgactaat tcaaataaat caggataatg ttctttaaca
    53641 tgcaatacat attcatttga actaggtagg ccgaacttta atctatagta agccggtata
    53701 aggtggcggc gaagattttc tctcaatcct tccctttgtt taaaatgtaa caaagaaata
    53761 tcttccattc tacttataat agcctctgtt aattgattaa agtaaaccgg agcaacatct
    53821 acttcacctt caaagcaact tgataataaa actgtgatat agcgataatc atcctcagaa
    53881 aacaccgtat ctataattcc caaatcaacc actgtatcca ataaaatagt ggttatatct
    53941 tgaataacag gagatactaa tgtctctgaa agacatactc tttcaacatc cctttgatac
    54001 ctacacagaa tgaatactaa accgaaaagg taaactttta attgattaac aataggtact
    54061 agctgtagct tctcataata atctttaact acctgattta tcaaatcata agttaatgaa
    54121 tacccccaac tggataaaac ataatccaaa ccccaaatcc ctatggagga ttccagcaac
    54181 tcactaacca tttgaaaagc taagcggtgc ttattccact ctgaaccgtg taaagtataa
    54241 ccttttgctc tactgtaccc tagctccaaa tcattatcta acataatctt tcttaatgat
    54301 tgaatatcag ataaggttgt attcttactt actttcaaaa agtcttggta atgattattc
    54361 gatataaaat ctaatcggca aaaagtgtaa agatagatta aagctaagcg agtcgacttt
    54421 ggtaaaacca attcatccga cttaataata tctgtcaaag actgcttcgt acgatttgat
    54481 aaactatagc gaccttgttt tttatccagc actatccctt tattagctag ataaggcact
    54541 aaataatcta ttccttcttt gacttccttt ataggtaagc tcaccttaac agataattca
    54601 tataatgata gctcacaatg atccatcaaa gtcatcaaaa taactagtgc tctataatca
    54661 aacatttctc ttcctttcta actacaatta tagtgtaaaa attataagaa taaaagagta
    54721 tttgagcaca atataatctc accttttaaa agaaattatt gggctgaaag tttttagtga
    54781 ttattttcaa ctttctattg acttttaaaa acaaagtgat atcatttaga tatcaaataa
    54841 tgggaggtca ttcttatgac tgaaaaacta atcaattcaa aaccaaatgg tgtattcgca
    54901 ttgattctca ttgagttgac aatcgtactt ggtatcttta tatttataat gggtgttggt
    54961 tcggaaaaca tttttggaat tattatcgga cctttactaa tcgtaattgc aggtctagct
    55021 catgctggtt taaaagttgt caaacctcag gaagctctgg ttctgacact ctttggtaat
    55081 tatacaggta ccatgaaaga acctggtttt tactttgtca atcccttcag cgtagcagtc
    55141 aaccctgcaa accacactcg acttggacaa agtggtgatg ttagcacaaa atctcctttt
    55201 ttaggagcta aatcatcaaa tgacaatgat gtaaatcttg aaattggcaa gaaacacatt
    55261 tccctcaaag tcatgacctt gagcaattct cgtcaaaaaa tcaatgattg cttaggaaac
    55321 cctgtagaaa tcggtatcgc ggtaacttgg agagttgtcg ataccgctaa ggcagtcttc
    55381 aacgttgata actacaaaga atatctttca ttgcaatgtg atagcgccct ccgtaatatt
    55441 gtccgcatct atccttacga tgtgtctcct aatgtggata ctacgggtga cgggcaagca
    55501 gatgaaggta gtctccgtgg ctctagcgaa attgttgcta accgtattcg tgaggaaatt
    55561 caaagtcgcg tagaagatgc tggcttggaa atccttgaag cacgtatcac ttacctagct
    55621 tatgctccag aaattgctgc cgttatgctt caacgccaac aagcatctgc cattattgat
    55681 gcacggaaga tgattgtaga tggtgctgta ggaatggttg aaatggcact agaacggctc
    55741 aatgaagggg aattggtaga acttgacgaa gaacgaaaag ctgccatggt ttcaaatctc
    55801 cttgtcgttc tttgtggcaa tcatgatgca caaccaattg tcaacacagg aagtctttac
    55861 taaagatggc tgaagctaaa aaaaagcaga tcccccttcg actctcaaca aagttatacg
    55921 ctgcactcgc atcatgggca gaagacgact ttcgttcagt caatgggcaa atcgaatatc
    55981 tcctcacaga gtgtgtcaag caacggaaaa aagacggaaa atacgtatca gaaaccattg
    56041 acgaaccatt tgagattgat atttaacacc ttctcctgtc tgccgtgtcg gataggagaa
    56101 ttttttcatc tttttttgtc aagtaacttt actttacaaa aaaaatgtgt tatcctagta
    56161 tggttgatga aaatcagtag attgaatcga atataaatac ctaaaggaga aatcaaaatg
    56221 gcagtacctg cacgtcgcac ttcaaaagcg aagaaaaaca aacgtcgtac acactacaaa
    56281 gtaacagctc catctgtaaa ctttgacgaa actactggag attactcacg ttctcaccgt
    56341 gtatcactta aaggatacta caaaggacgt aaaatcgcta aagctgcatc agctgaataa
    56401 tagaagggag ataccatgcg cgtaaatatt acacttgaac acaaagaatc tggtgaacgc
    56461 ttgtacctta cttctaaaaa caaacgtaac actccagacc gccttcaatt gaagaaatac
    56521 tcaccaaaac ttcgcaaaca cgttgtgttt acagaagtta agtaagcatt caatacgaat
    56581 caatacagaa gaaaaacgct tgatcagcgt tttttctttt tgttaatttc actatattgc
    56641 aagggaaatc attcgaatga ctacattatt gataatattt gttaagccat caaaagtaat
    56701 taacatttca tagcgagtaa tcctatttaa actcgtccca ctatctattt cttcttatct
    56761 ctgtgttata atcccgactt tatcataagt ttgtctaact gtagcatttg aaaccagata
    56821 attcttctgt ttcacgcgaa acaccctgcg ccaagcaagg tgttcttgtt ttcatactca
    56881 atgaaaatca aagagcaaac taggaagcta gctgcaggct gctcaaaaca ctgttttgag
    56941 gttgtagatg gaagctgacg tggtttgaag agattttcga agagtattaa gtcgtataaa
    57001 tcgtcgaagc tgtcgcaatg gtatgccact ggttagctgt agttgctgcg aaatccttgt
    57061 ctgcgtagaa gtcagtaaat ggtaggattt caacttccag ctcgtcgata cggtcaagct
    57121 ggccagccag ataaacctcg atacggcttt ctgctcgttt gatgcgttgc aagagtccgc
    57181 ccatacggat gtcaactgta tccaaaccaa agaccttgtt ttctttcagc cattggtgac
    57241 taaagagggc atggaagtct tcaatttggc ttctaagttc tggtaattct tgtctggcga
    57301 tttgttgtaa actttcttta tcatccgctt ggtaggcatg acgaatgcgt cgtcccacat
    57361 ctactttgct acttaaaata gcattcaact gggcctgagt ttcaaagaga taagcatagt
    57421 ttccagcttt ttctttaatg tcagcaatag ttcccgccgc ctgagcgaag tgtggcttgt
    57481 cctgttcagg tgtcatgtgt cggtcaagta tcggacagag aacatcctga taaaagacat
    57541 agcggttggg attgatgcca ctgagattac ctggtaggtc tggtaagagg ttggcaagat
    57601 caatctgcat aaaatcctca accgttagac cagtattggt cttgaaatgc gcagacaaac
    57661 tatctaggtc attgcgatag ctgagttctg cccagatttg caagcttggt aggatagaga
    57721 actgggcagt ttcaccacca ttgtctcccc aacccgttac gatgacttct ttaatctgat
    57781 tggcacggca ggctttatta gcctcgatag ccactagacg gctaaaatgg ttgtgaggtg
    57841 taaagccaat ccacttccaa gctccccctg caaatgcaag gtcatggcta atcttgtgat
    57901 gattgcggaa attacggttg tatttttcct cgctatcctg ataataatcc cagtaaacca
    57961 gagtcacacg gtctttgaga cggtctaggt agacacgagt ttcctctgga atttccacat
    58021 cacggtcgta ctggccatcc gctgacatga gtttgaagaa catatcactc cacatctggc
    58081 agtggaaacc atatttgtca gcaatatcca gcatgcgctc caagtgttgg cacatgagga
    58141 gactacgatc cacaacaccg ttcaaaatca ggtagcgtcc caaaccaacc aagtgggctt
    58201 cgtccatccc gatattgacc ttgcgagtct tcagtttaga caacgtggca aacatgccat
    58261 caatcaggtc ataaaccttt tcttcgccaa tgagaagaat gtcctctaca tcacggagct
    58321 cctgcacttc cttgacaccc catttgacaa aggccgacaa gtgggccaag gtctggatgc
    58381 atggtacaaa ggtcatgtca aactgttgag cataggcttc gatttcctgc aactcctctg
    58441 ctgaataagc tccacggaaa tagccaaagt aaggctgccc ttcaatctgg taagtgtctt
    58501 ccatgtaaag ctcaaaggtt gagtagccca tgagagccaa gacctcaatc atctgcttgg
    58561 cagaagccac attcagcacc gcatttcgag aacagtcaac catgtaagcc aaatcttcgt
    58621 aagctgcttg ttcctcaatc tctactttat cagcttctgc tagaactgtt accaacaagg
    58681 acaaggcacg atagagttgg tgaggtttgc ggtaggtcaa ttgatagtga ccttcctcac
    58741 cctcgataga gatagaggct tggtcagact gagtgacagc cacttccaca tctggtagag
    58801 aaatgtgacc ttttaaaacc tcaatagctt gcgtttgttt gggactaagt cctgtaaatc
    58861 ttaccattgc ttttcctcct gtagccagtt gacaagagca ccgtagagat tggcatctgc
    58921 gtgataggtg caggcctgga taactggtgc gaccgtgtat tcttcgtagg tatcgacaaa
    58981 gttatcaaca gccttcttga catcttggat aaaatctgga ttttgactga tagagccacc
    59041 cagactgatg acatctggat cgatgagata ctggatattg agcaagcctt gcgccagatt
    59101 gcggttcatg cgctcaatgg cttcttgaca aagagcatta ccagctgcgg cctcttggta
    59161 aatcttgcga ccgtcccaat cagtatgacc agatttttca atcacgtatc gtaccatatt
    59221 cccagttgac gctagttgcg accagttatt aagtttttca gcaggggcaa gggttgtcat
    59281 gtagccaaat tctccaccca agccgtggcg acctcgatga agtctaccat tgataatcat
    59341 ggctccgcca atccctgtcc caatcacgac acaggctgca ttttcaagct ctgaatgagc
    59401 tagtagttca ctgagtccaa cgcagttggc atcattttct aaatggacag gtagctgata
    59461 agagctaagc gcctcatacc aagaaaagcc atggatgtag ggcaccgcac tgaagccatc
    59521 aatcacacct gtctcttgat tgactgcacc tggaacgctc atagcaatcc cactgtaatc
    59581 ctgttctgac aagcgttgat ctagccacgc tagtaaatcc tccaagtttt caggcgttga
    59641 aatacttgtc ttatccagta ttttcccatc aggagtcaga ctggcaaact taatcccagt
    59701 ccctccgata tcaatcgttg caatggtcat tgtttttacc ataaaaaggg gcgaatcagc
    59761 agttagttct tactttttcg cccctccttt cttttgatgt ttactttttg aaattaaatt
    59821 tcttcttttt tgatgaattc tgtacgaatc tcttgtggat ccaatagtcc tgaatgaact
    59881 ggatatggtc gctcaagtaa gtcaagaatg gtttgttgat gttctgatat gcgcacattt
    59941 tcttgactca tattatagta acggaggaca tagccttctt cattttccgc cactttaaag
    60001 gctgttggac aaacttgcgg tatgctgaga acagaatggc tcaagaggct accagtcgca
    60061 accacgattc cttcctgtct agcaagctga aggctggtaa acggtgtctg caaggctttg
    60121 gcacgacgat aggctgagaa gcgttcttgg gcttggtggc attcaagtgc aaactcgact
    60181 tcaaactcac gcaagcattg tgcttctggc gttgggaagt agccccagtc acctagctca
    60241 cctgatgcac gcaaaatggt cacggcaatg gtgttatccc caaggatttc gtattcattc
    60301 aatcccttat tggatacagt cacccctttt tcatcgtcat acagactgac aaaagcttgt
    60361 tggtgttgag gattttcagg gttttcccat gaagcagctg gtttgtttgg tcgtgtcacc
    60421 acctcataga tactttcaga atcattgctt ggacgcgtgt tatgagtctt gaccaagaga
    60481 cggatacggt gatccttggc agtgttagta aagcgagtct tgaagcggat ttgtggattg
    60541 tcaacaaaga cagtcaactc agtttccaga ggaatgtttg tcaattcttc tgaccgtcca
    60601 gcttcacgct tcatgaactc gatgatacct ttttgctctt cttctagctt ttcatctgca
    60661 ctgacaggca cggtcaattc atgtttgagc aagattttag cgtagcgagc tgtgttttcc
    60721 aagacctcgt ggcccttaag ctctgcaaag attggctctg ttccttttgg ttggaaatag
    60781 atatactcgt ttccgatgtc cccacggtct tcaaagcgga taaagtcttc ataggcttcg
    60841 tgagttgtct tgtcatagac tgtgatgttg tcatccacac tcaccgttac gaatggtgta
    60901 tcaatcactc cgttttggta aataccctca cggtgttctt gttttccttc cagcaattgg
    60961 aaggttgtcc aagaaagcgg cgctaggtga actggaatgg tcacgcgcac ttgacgagca
    61021 atacgagctt ggcggaactt gtcttttggt aaatcatact caaaattagc tccgaggtct
    61081 tcgattgtag cctctacagg acgaccatcc aagtcctcca cacggtaact tggcaagata
    61141 agagcagcca tctttttgta gccttctgtt gggtgcaatt ccttgaaatc acaagtcgcc
    61201 acatcaatca ctgtgctgac agtatcgacc ttatcatgca agcctgtgtt aatgacagta
    61261 aagagatagt cactttgagc cttatccgta gcaattttac ccttccactc gttgagcaag
    61321 ttacttttaa caaagtttcc tacttggttg accttggcaa aacgcgtttc catctcgcgg
    61381 tgaacttcgt ccacgctaca gccacagata ctatcatgtg gcgcattctg caaaagtgtt
    61441 ttccaagcat aggtcaactg gtccttgtgg ttgtgtccac cagtgataat agtcaagggt
    61501 tctaccactt gctctaggag gttgctattt tcttggaagg cttgttttag gtaaatgcgg
    61561 gatgaagaag tgttggcaag tgtgtaccag ccatctgttt cctgactggt caactcacct
    61621 gtaacagttg ataagtgttc aggaagcgca ccttctacag cttgaacata ttcatcaaaa
    61681 gaactatgaa caaagattac atccgggaag agttcatttg ccacacgaat ggcttcgctc
    61741 agatttttct ggacaggctg gtggtcacag ccgttcatca tcaaccattg gttggtcgaa
    61801 gcgtaggcac gcacatctga caatttttgt ttccagaagg tcaaggcctc atctttgtca
    61861 actggaattt cattcccgtt actgtaccag ttggcaaaga gaatacctaa aacacgacta
    61921 ccatccacac cctgccagta catttctgaa aactgagacg taaactgctc atcttcaagg
    61981 acttggttgt caaatccaat cggcttcaca ccacgaccaa aggccgccac gtgaatgcct
    62041 gatttttgaa gaatttgagg cgcttgtccc atatttccaa aggtatctgg aaagtagcca
    62101 atctgggttg atttacccca tttggcagct tcttgttgac caatcaaggt attgcggaca
    62161 ttggcttcac tggagatcaa ataatcatcc tgcaagatgt aaaagggacc aattttaagc
    62221 ttgccctcgt caatgtagcg ttggaccttg tcgcgatttt cagggcgaat ttgtaagtag
    62281 tcgtcaagga caatagtttg tccatccaag tggaaactct tgaactcagg gtcattttca
    62341 aagagatcaa agagattgtc aaacaattcc accaattgca tacgatggct ttcaaaaggc
    62401 aagtaccact cacgatccca gtggctatgt gagataatat gtacaacaac attttccatg
    62461 aagtaaaacc tcattctaaa tttaaatttt aacgttttaa atgtaaactt gtgattctga
    62521 taagaatcgg ttgagctaaa gcgagcccct tagcgaatat ccaagtaatc caagaccaac
    62581 tcacagaaca tcatgttagc ccaggagaac cattcacgag agtagagggt cggatcatct
    62641 acatggaagc tttcgtgcat gacacctgta ccaccatcgc aggcaaccag ctgatccagc
    62701 aagaattttt tctctgcctt atctcttgtt gtcaatcctt ggatagaaag ggcgattggc
    62761 cagatatagc gatagaaggt atgagaactt ccgagaccgc tagcgtattc tccttggtag
    62821 aagtatggat tttcagagct cagaatggta cgacgagtag cttgatacac ttcatcatcg
    62881 accgaacagt agcccagata gggcgcagct agtagacttg gtacatttgg atcatccatg
    62941 atgctggcat ttcctaggcc atccacttca aaagcgtaaa tcttttcgcc cttgctgttg
    63001 atggtgtaag cgtagttttc gattccttct tggatttcat cctgaagacg cttggcatca
    63061 gcaataacac tctggctatc agctaggttt aatgctgcga agatttcttg cacataaccc
    63121 aagactacta cagcaaacat atttgacgga atcaagtaac tatactggca acagtcatca
    63181 ctcggacgaa aggctgacca agtcatacct gtcactgcaa agtcaggtcc aaagccatca
    63241 tttaccaagg tatcttcctt acggtccgta tctcggacaa aacgataagg agagttcttg
    63301 tggtcttgtt caactgtcca tagatggaga atttccttag tcgctgcgac aaaaatctca
    63361 tcaaactgac tagtctcgcc agtctctttc cagaggagat aagccaactg caaaggatag
    63421 caaagcgaat ccacctcata cttgcgctcc cagatccagc cgttaaggtc tgtgtggtca
    63481 gtctcgtggt gccctttcca gttctcctca atgttgaagg agttagcata gggatccttg
    63541 agtaccaagg tcatctgacg tttgaccaaa cctgcaatgg tctgacgcag gagggcatct
    63601 cttttagcta catgaaggta gggtctgagt tgggctgtcg aatctcgaag ccacatggca
    63661 ggaatatccc cagtcaagac aaaagttgaa ccatcttcta agatttcaac cgtattgtcc
    63721 aaggtatcgg tgtagcaacg ctcaaagaca tccacccact ctggatggtc cttggcccgc
    63781 tctgctactt catctagcca ttctctaaca atttctttcg aataaaccat tttaaatttt
    63841 acctctttca aacaagtttc attttcagta tatagctttt gagacagaaa atacatacac
    63901 aaatgatagt catttttcta caaaatagtt atctttaaaa ctccttttct aaaggccctc
    63961 tttttctgat ataatgtaga aaaacagcta aaggaaagac tatgaaacca ctacttgaaa
    64021 ccatcgatac ccgctttggt actgctagca agcatgcctt ctctcgggga aataccctgc
    64081 catacacagg cgtgcctttt gggatgaatt attttgtgcc ccagaccagt gaccaggatg
    64141 gatcttggtt ttttgatccg catctgccta tctttcaggg gattcgatta actcaccagc
    64201 ccagtccttg gattggggac tactcttggc tccttctgac acctgtcacc agtcaactgg
    64261 gtggagacag cctctttcac cgccagtctt cttatgatat agataaagct tgcttccagc
    64321 ctcactattt gaagctcttt tccctgcgct atcaaattga aacccagctc acaccgactt
    64381 gctatggtgc ttctattcgt ttgaagcaaa agcaaggcaa agccctctcc ctctatcttc
    64441 acgcagcaga tgaactaaca gttgagcagg tagataagcg gactctggct ctcagacaag
    64501 aaggcaaaac agagaccaat aaaaatccac tgatgctctt cactgccctg caaatgaaca
    64561 cggatattct tgctatcagc caagaagggg gagactggcg aattgactta gcaagtagtc
    64621 aaaccgagat gcaactagcc acttctttca tctctccttc tcaagctcta atcaatctac
    64681 ctcaagaaga ttttgatagc tgtaaagcaa gtgcccaagc ggattgggaa aatctcctcc
    64741 atcgttttga cattatagag acaggagagg ctgaccgaac cttctttgac cactgtctct
    64801 acagactctt cctcttccca cagacttttt atgaggttga tgagtcaggg caagccatcc
    64861 acatggatct ggctactggt actgtcaagc ctggtgtcct ctttagcaac aatggtttct
    64921 gggatacctt ccgcaccacc ttccccctct ttgcccttat cataccggag cactatcaac
    64981 gctttttaga aggtttcctc aatagctacc gcgatactgg tttccttcca aaatggctgg
    65041 ctccagatga acggggtatg atgccaggta cacttttaga cggtattatc gcagatagcg
    65101 cctgcaagga catggcccct gacctagaag aagaactctt ccaagccatg ctcgaaacag
    65161 ccagcaaagc cgaccctctc ggcatcaatg gccgccacgg actagcccaa taccaagaac
    65221 taggttacct ctctaccgac caccacgaaa gtgttagcca tactctagac tatgcctata
    65281 gtgacttttg tatcgccagc tgtgccaaaa aactagagaa catagaaatc gctgaaacct
    65341 acaaggctgc ttcacaaaat taccgccagc tatttgacgc tgagacaggt tacatgcgag
    65401 cacgagacaa tcaaggaaac tttcaccctg acttctctcc ttatagttgg gggcgagact
    65461 acgctgaatg ctctgccatt caagctactt taggcgttct ccacgacatc cctggcttaa
    65521 tccaactgat gggtggaaaa gaaaccttta gcaactatct tttgaaagcc tgtcaagatg
    65581 ctcccctctt tgaaacaaca ggctatggtt acgaaattca cgaaatgagc gagatggcta
    65641 ctgctccttt tggacaaata gctatttcca accagcctag tttccacatt ccttatctct
    65701 tccgctacag cgattaccct gactacactg cccttcttat caagacgctc cgtcagaaag
    65761 cttttcaccc aagttgggaa gcctatcctg gagatgaaga caatggtagt ctctctgctt
    65821 ggtacatctg gtcagctctc ggattttatc caacctgtcc aggaaaacca agctatgatc
    65881 tcggaattcc tctctttgac catctacgag tctacctagc taaagaaaat aaatggctag
    65941 atattcatac tgagcaaaac cacagccatt ttaactttgt caaagaatgc cgactggaca
    66001 aaacactcgt atcaactatt caacaccaag acctcctaaa agctgaacaa ctaactttca
    66061 ccctcagctg gctaccaaat cactaataac caaaagaacc tttgcatcgc gcaaaggttc
    66121 ttcttttatg aaacttggac ttgaagttga tccacaagct gaccatccac cgttaggttc
    66181 agatagaaat ccaaggtttt atctcctgcg aaatacaagg ttggtagcgt cagccttttt
    66241 tcagtctcac cagcttgaaa cgcaaggaca taaatctcgt cctgataggc gacaccatgg
    66301 acacctgtcc ccggttgaat cgaaatctta gcctctaaag aggagctact ttcactacgt
    66361 tcaatcctaa aatgaagagt ctctcccttt gccacagcta ggcttttttc tgcaaatgct
    66421 agttcctgaa caacttcttt ttttgataac ccaggagttt tataaaggga aatcttggtc
    66481 aatacaggga tagattgtgc ctcggtaatc atcacgcgca ccttttgtgc ctctactagc
    66541 ggacctcgca agaggcgctt atgaccaact gtgaagcccc tgccaaactc ctgccagaca
    66601 ccatccacct ctacttgcac atgaaaagca gcgattcgtt gccctagctt caaatcttct
    66661 cttaactcaa ttacatcaaa agttttagga gaacctaaat cgagttctaa ctggatgggc
    66721 aagtctgcat cgcttgccca agagctggtc tcaaggccgt ctgtcaaatg gcgacaagca
    66781 aagtctgcgg aaagagctgg accagatacc tcagctccca gagccaaatc ttctttatag
    66841 agctcattgc gataggtcgc aaattcataa agtcgttcaa tatcctttgc atcaaagagc
    66901 ccagcttgat tcggcggaat attaagcaag agtggagttc ctcgccctac tgagtgaaag
    66961 tagatttcga ccaactcctc gagagactta ggatcctgat cctcatggta gaaccagcct
    67021 ggacggatgg aaacatctgc ctctccgatt gaaaaaatcg tgcccgaggg atccccgtgc
    67081 tgaagatagt tcagctctgc ttctgttcct agtttatcag gattcacctt ttgccacagt
    67141 ggatcacctg cataccctcg ttcattgcca atccagcgga tactggtgcc ttctgttgaa
    67201 aaaatcaagc aagcgccctg caggtcacga atggtttcaa accatttttc aaattcataa
    67261 ttaacctttt gcgcgccctc tcctctggca ccatccatcc aaacctcagc gaacttacca
    67321 gcattcccat agttaggatt tgataagatt tccttcaact gagtcagata ataggcattg
    67381 tagtccgctt ctcggtccac atgatagagg ggactatggg catcccacgg tgacaggtag
    67441 acccccatat ccatatcaaa ctctgtggca gcttgggata cttcaaggag caagtcgccc
    67501 tttcctctcc tccaaggact gaccttaacc gaataatctg tgtgagctgt cggataaagg
    67561 acaaagccat cgtggtgctt gaccaccaaa atcaactttt tgaagcccgt ttccttgagc
    67621 acacgaaccc actcacgcgc atccaactga ctcgggttaa agcgctcagg atcctcctgt
    67681 ccagtccccc attcttggtc ataaaaggta ttaggaccga agtggataaa agctgctagt
    67741 tcatctccca gataagctag ctgagtctga cttggtaacg gtccatgcgg tttgattttc
    67801 ttcatcgtta tatatctcct tctttagcaa cttctcttgt tcacaaggtt atccacaggt
    67861 tgtggataat aaaccatgat ctaacagcca gctctttcca actccaactg gtaggctcag
    67921 gatttttctc ctcaatattc cctcttcaaa cagctctgtc atatggttct gctaacacct
    67981 ctcagaatgc tactctccat aattattctc aggcttcttt caggtcattg tgtgaagacc
    68041 attcactctc cagacttttc cacagattgt gaataagtga ttattctaaa ctatcacctc
    68101 gtcgactata acaaaaaata aaaagagggt caataagata attatctctt cctaaatact
    68161 cagaaaagat tctataattt gtacaattga acaagaaatg cttctccaaa atctatcttc
    68221 aaaagaatgt tgcatctttt tatcctttca cacaaacatt tctctttata cagatccaag
    68281 tgataaccag atgataattg gacacttttt agtcatttgt atattttttg aaaaattttt
    68341 taaaaaaatt ttatatcctt tttatagaag tttatgcatt tgtatctatg tattctatcc
    68401 tatgttatgt ataataacat aaaattgtgc taaacatcat aatttatatt attttccgag
    68461 aaattatagc cattgacatt acctaggaat tgcgttataa catacatgta agcggtaccc
    68521 aaaatggtgc caagtcaaaa tttttaagga ggaaaataca tgtcttctca tccaattcag
    68581 gtcttctcag aaattgggaa actgaaaaaa gttatgttgc accgtccagg caaggagtta
    68641 gaaaacttgt tgccggacta tcttgaaagg cttctttttg atgatattcc tttcttggaa
    68701 gatgctcaaa aagaacatga tgcatttgcc caagctcttc gcgatgaagg aattgaggtt
    68761 ctctacctag aacaactcgc tgctgaatca ttgacctctc cagaaatccg cgatcaattt
    68821 atcgaggaat acttagacga agccaacatc cgtgatcgtc aaaccaaggt tgctattcgt
    68881 gaattgcttc acggcatcaa ggacaaccaa gaattggttg aaaaaacaat ggctgggatt
    68941 caaaaagttg aattgccaga aattcctgac gaagctaaag atctaactga cttagttgaa
    69001 tcagattatc catttgcaat tgacccgatg ccaaacctct atttcactcg cgacccattt
    69061 gcaacaattg gaaacgccgt atcgcttaac cacatgtttg cagacactcg taaccgtgaa
    69121 acactctacg gtaagtatat cttcaaatac cacccaatct atggcggaaa agtggatttg
    69181 gtctacaacc gtgaagaaga tacgcgtatc gaaggtggag acgagctagt tctttctaaa
    69241 gacgtccttg cagtaggtat ctctcaacgt acagacgcag cttctatcga aaaacttttg
    69301 gtcaacatct tcaagaaaaa tgttggcttc aagaaagttt tggcctttga atttgctaac
    69361 aaccgtaaat tcatgcactt ggatactgtc ttcactatgg tagactatga caagttcact
    69421 attcacccag aaatcgaagg cgaccttcac gtttactcag ttacttacga aaacgaaaaa
    69481 cttaaaatcg ttgaagagaa aggtgactta gctgaacttc ttgctcaaaa ccttggtgta
    69541 gaaaaagttc atttgattcg ttgcggtggt ggcaatatcg tagcagctgc gcgtgaacaa
    69601 tggaacgacg gttctaacac tttgaccatc gcacctggtg tggtagttgt ttatgaccgc
    69661 aataccgtga ccaataagat tttggaagaa tacgggcttc gcttgattaa gattcgcgga
    69721 agtgaattgg ttcggggccg tggtggacct cgttgtatgt ctatgccatt tgaacgtgaa
    69781 gaagtgtaat cgctgttcgg cattcgtcaa tagaaaatgt aaaaaataga aagaggaaat
    69841 aataaaatga caaattcagt attccaagga cgcagcttct tagcagaaaa agactttacc
    69901 cgtgcagagt tagaatacct tattggtctt tcagctcact tgaaagattt gaaaaaacgc
    69961 aatattcaac accactacct tgctggcaag aatatcgctc tcctatttga aaaaacatct
    70021 actcgtactc gtgcagcctt tacaactgcg gctatcgacc ttggtgctca cccagaatac
    70081 ctcggagcaa atgatattca gttgggtaaa aaagaatcta ctgaagatac tgctaaagta
    70141 ttgggacgta tgtttgacgg gattgaattc cgcggattca gccaacgtat ggttgaagaa
    70201 ttggcagaat tctcaggcgt tccagtatgg aacggtctaa ctgacgaatg gcacccaact
    70261 caaatgctcg ctgactactt gactgttcaa gaaaacttcg gtcgcttgga aggcttgaca
    70321 ttggtatact gtggtgatgg acgtaacaac gttgccaaca gcttgctcgt aacaggtgct
    70381 atccttggtg tcaatgttca catcttctca ccaaaagaac tcttcccaga aaaagaaatc
    70441 gttgaattgg cagaaggatt tgctaaagaa agtggcgcac atgttctcat cactgaagat
    70501 gctgatgaag cagttaaaga tgcagacgtt ctttacacag acgtttgggt atcaatgggt
    70561 gaagaagaca aattcgcaga acgtgtagct cttcttaaac cttaccaagt caatatggac
    70621 ttagttaaaa aagcaggcaa tgaaaacttg atcttcctac actgcttgcc agcattccac
    70681 gatactcaca ctgtttatgg taaagacgtt gctgaaaaat ttggtgtaga agaaatggaa
    70741 gtaacagacg aagtcttccg cagcaagtac gctcgccact tcgatcaagc agaaaaccgt
    70801 atgcacacta tcaaagctgt tatggctgct acacttggta acctttatat tcctaaagta
    70861 taattttaga taataaaccg tctaccaaca gctatgaggg ctgcgactaa tagctttagt
    70921 ccggtcctct tttatataat ggtaatctat tatttcttat aaaatatgtg aaaaatcatt
    70981 aaattgaaat ctaaacgcat tctattgagt gtgataaagg agaatttatg gcaaatcgta
    71041 aaattgtagt agctttggga ggaaatgcga ttctttcttc tgacccatca gcaaaggctc
    71101 aacaagaagc tttagttgaa acagctaagc atcttgtaaa attgattaaa aatggagatg
    71161 atttgattat cactcacggt aatggacctc aagttgggaa tctcttgctc caacatttgg
    71221 catcagactc tgaaaagaac cctgccttcc cactcgactc acttgtcgct atgacagaag
    71281 gtagcatcgg tttctggttg aaaaatgctt tgcaaaatgc tctcttggat gaaggcatcg
    71341 aaaaaaatgt tgcctctgtt gtaacgcaag ttgtcgtaga taaaaatgat ccggcttttg
    71401 ttaacttgag taaaccaatc ggtcctttct attcagaaga agaagcaaaa gcagaagccg
    71461 aaaagagcgg agcgactttc aaggaagatg ctggccgtgg ctggcgtaag gtcgttgcct
    71521 caccaaaacc tgttgatatc aaagaaattg aaaccatccg tactctttta aataatggtc
    71581 aagtcgtcgt agctgcaggt ggtggcggta ttcccgtcgt caaagaaaac aatggacatt
    71641 tgactggtgt cgaagcggtt attgataaag acttcgcttc ccaacgtttg gcagaattgg
    71701 ttgatgcaga cctcttcatc gttttgacag gtgtagatta tgtatttgtt aactacaaca
    71761 agccaaacca ggaaaaattg gaacatgtga atgttggcca gctggaagaa tatatcaaac
    71821 aagatcagtt tgcaccaggt agcatgcttc caaaaataga agcagctatc gcttttgtca
    71881 atggtcgtcc agaaggaaaa gcagttatta cttcccttga aaatctaggc gcattgattg
    71941 aatctgaaag cggaacaatt attgaaaaag gataagttgt tttactaata agatgtattc
    72001 tatttctagt atctttatat caaattagaa attattcttg aaaacatgta caatatttca
    72061 aaagatatta gttttttaga ctttaatatg gtaaaacaaa tataaataga aagcgttttc
    72121 tttaatgttt atttaagaaa gtagttggtt ttttacactt tgttagacat caggaggaaa
    72181 aacaaatgag tgaaaaagct aaaaaagggt ttaagatgcc ttcatcttac accgtattat
    72241 tgataatcat tgctattatg gcagtgctaa cttggtttat ccctgcgggg gcctttatag
    72301 aaggtattta cgagactcag cctcaaaatc cacaagggat ttgggatgtc ctcatggcac
    72361 cgattcgggc tatgctaggt actcatccag aggaaggttc gctcattaaa gaaacgagcg
    72421 cagcgattga tgtagccttc ttcatcctta tggttggggg tttccttggc attgtcaaca
    72481 aaactggtgc tcttgacgta gggattgcct ctatcgtgaa gaagtataag ggccgcgaaa
    72541 aaatgttaat tttggtactg atgcctttgt ttgccctcgg tggtacaact tatggtatgg
    72601 gggaagaaac aatggccttc tatccactcc ttgtgccagt tatgatggcc gttggttttg
    72661 atagcctgac tggtgttgca attattttgc tcggttctca aatcggctgt ttggcatcta
    72721 ctctgaatcc atttgcgaca ggtattgctt cagcgactgc gggagttggt acaggggacg
    72781 gtatcgtact tcgtctgatc ttctgggtta ccctgactgc tcttagtact tggtttgttt
    72841 accgttatgc ggataagatt caaaaagatc cgactaagtc actggtttat agtactcgca
    72901 aagaagattt gaaacacttt aacgtagaag aatcttcatc tgtagaatct acacttagca
    72961 gcaaacaaaa atcagttctc ttcttatttg tgttgacatt catcttgatg gtattgagct
    73021 tcattccatg gacagacctt ggcgttacca tttttgatga ctttaatgct tggttgactg
    73081 gtcttccagt tattggtaat attgtcggtt catctacttc tgcactaggt acttggtact
    73141 tcccagaagg cgcaatgctc tttgccttta tgggtatcct gattggtgtt atttatggtc
    73201 ttaaagaaga taagattatc tcttccttca tgaatggtgc tgctgacttg ctcagtgttg
    73261 ccttgatcgt agcgattgct cgtggtattc aagttatcat gaacgacggt atgattaccg
    73321 atacaatcct caactggggt aaagaaggct tgagcggtct atcttcacaa gtctttatcg
    73381 ttgtaactta tatcttctat ctacctatgt cattcttgat cccatcttca tctggtcttg
    73441 ccagcgcaac tatgggtatc atggctccac ttggagaatt tgtaaatgtc cgtcctagct
    73501 tgattatcac tgcttaccaa tctgcttcag gtgtcttgaa cttgattgca ccaacatctg
    73561 gtattgtgat gggagctctt gcacttggac gtatcaacat tggtacttgg tggaaattca
    73621 tgggcaaact cgtagtcgct attattgtag tgaccatcgc ccttcttctc cttggaacct
    73681 tccttccatt cctataaaat ggtgagtgag gtgattccat gaaaatagat ataacaaatc
    73741 aagttaaaga tgaatttctt atatcattaa aaaccttgat ttcctatcct tcagtactca
    73801 atgaaggaga aaatggaaca ccttttggac aagcaatcca agatgtccta gaaaaaactt
    73861 tagagatttg tcgagacata ggtttcacta cctatcttga ccctaaaggt tattacggat
    73921 atgcagaaat cggtcaggga gcagagcttc tggccattct ctgtcatttg gatgttgttc
    73981 catcaggtga tgaagcagat tggcagacac cgccatttga agcaactatc aaagacggct
    74041 gggtattcgg acgtggtgtc caagatgata aaggcccttc gctcgcagct ctctatgcag
    74101 taaaaagctt gctggaccaa ggtattcagt tcaaaaagcg cgtacgcttt atctttggta
    74161 ccgatgagga aaccctctgg cgctgcatgg cacgctacaa taccatcgaa gaacaggcca
    74221 gtatgggctt tgcacctgac tcatcttttc ctctgaccta tgctgaaaaa gggcttctac
    74281 aggtcaaact ttatggctct ggatcggatc aactagagct tgaagtagga ggcgccttta
    74341 acgttgtacc agacaaggcc aactaccaag gtcccctcta tgaacaggtt tgtaacggtc
    74401 tcaaagaagc tggttatgat taccaatcca ctgaacaaac cgtaacggtt ctcggagtgc
    74461 caaagcatgc taaggatgct agtcaaggta tcaatgctgt catccgacta gctaccattc
    74521 ttgctcctct ccaagaacac cctgctctca gttttcttgc aacacaagca ggtcaagacg
    74581 gcacaggaag acaaatcttt ggtgatatag cagatgaacc ttctggtcac ctatccttta
    74641 atgtcgcagg tctcatgatc aatcatgaac gttctgaaat ccgtattgac attcggactc
    74701 ctgtcttagc tgacaaggaa gaactagtag agttgcttac aagatgtgca caaaactacc
    74761 aactccgcta cgaagagttt gactatctag cgcctctata cgtcgcaaaa gacagtaaac
    74821 tcgttagcac actgatgcaa atctaccaag aaaagactgg cgataacagt cctgctattt
    74881 catccggtgg tgccactttt gctcgcacca tgccaaattg tgtagccttc ggcgccttat
    74941 tcccaggagc gaagcagaca gaacatcagg caaatgaatg tgccgttcta gaagatttgt
    75001 accgtgctat ggatatttat gccgaagccg tctatcgact tgcaacttaa tcaggcaact
    75061 gtttctacca aaaaaaatcg accgattaat gaactgcacc ccaaaagtta gacagaataa
    75121 atctaacttt tggggtgttt tattatgaaa ttgaattatg aagataaagt tcagatctat
    75181 gaactaagaa agcaaggaca aagcttcaaa cagctttcaa aaagatttgg tgtggatgtt
    75241 tctggtctaa agtcatctga atctttgaga tgagctttat aaatcgcttt tttcagtttt
    75301 tgcactggtg tttcgataaa ctcaaacttt ttagccgttg tattgcctga ttttatagta
    75361 tattgaaact agaatagtac acctctactt ctaaaacatt tttagaaatc gatttgactg
    75421 tcctgattga tttgtcctgt tcttatttca ttttactata tttgagccac ttcgtcttta
    75481 acggctttat tcataagctc ttgtaatttt tctttactat caattacttc ttattttccg
    75541 ttgtaattta ttgtaatagg ttttaactta cctaatttct cgacacgctc attaatttga
    75601 tcttttttga aggctgcata tgtttttcct aagatttttt cgaaaatata tttatcagat
    75661 agcggtttgc cttcttcttc agcttggttt ttgtattgat ttgaaacata aggaacaaat
    75721 ccttcatagt aacctaatgc tcccataagt tcaaaagctt gttttctaat tcaaaccatt
    75781 gcaactcaga tttcagcttt tcagataaat cctgctcatc caaataatga cttgaaatta
    75841 gtgctgaact cgtttctgta tcctgtacag gctgagcacc cataccagca aaaaataaac
    75901 tcgttcctag caagaccgaa caagctccta ttgcatatgg cctcaaagaa aaacgctgct
    75961 ttctctcaaa ttgaaattct ttcatcccat ctcccatcat tcattattac tgtatatttt
    76021 gtatatcaga aatagtttgt attcacaaat ctttctagtt attcccttat cattcctaat
    76081 taagggagat aacatacaat aatttttagt taaatgtata tcgatgtttt ttgtttttct
    76141 taataaacgc aatacaaaaa gagcctgttg ccaagctctt tgtactcaat gaaaatcaaa
    76201 tagcaaacta ggaaactagc cacaggttgc tcaaaacacc gttttgaggt agtagataag
    76261 actgacgaag tcagctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagc
    76321 tcaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacat ctatacggca
    76381 aggcgacgct gacgtggttt gaagagattt tcgaagagta ttagtctatt atttcttctc
    76441 agcgcgaagg gctgacaaga tttgtgttcg gatatcatcc acaccatttg gcgtatttgg
    76501 taaaaagatg gtttgatttc ctttagaggc aaaggtattc aaggtatcca aatactggtt
    76561 ggtcaagagg atagacatga tttgttcttc tgtcatgcca acattggctt ccttgagttc
    76621 ggtgatagac tctgccaatc catccacaat cgccttacgt tgttgggcaa tccccacacc
    76681 atgaaggcgg tctttttctg cttcggcttc agctgcagtg acaattttaa tcttgtcagc
    76741 ttccgccaat tcttgtgctg cgacccgctt acgttgcgcc gcattgattt cattcatgga
    76801 ttgcttaact tctgcatccg gttcgacctt ggtaatcaag gttttcacga taatgtagcc
    76861 gtaagtggtc atttcttctg ctacttggtg ttgaacttca agggcaatct catctttttt
    76921 ctcaaacaat tcatccaagg ttaattttgg aacagaagag cgaagagcat cttcgatata
    76981 agatttaatc tgagattctg gacgtatgag tttatagtaa gcatctgtca cgctctgctc
    77041 gttgacacgg tactgagtcg ctacattcat cataacgaac acattgtcct tggtcttagt
    77101 ctcaaccaca atatcacttt gcaacaagcg caactgaatc cgtgctgcaa tcgagtcaat
    77161 cccaaaaggc aagcgaatat gaataccgct attggcaacc ttttggtatt tcccaaagcg
    77221 ttcaataatc gccaccgact gctgacgaac cacataaact gtactcagtg tgactatcac
    77281 caataggagc acacaaacaa tcagaaaaat catgaaaaat attgccataa tggaacctcc
    77341 acaagtattt ttctagtatt atagcacatt taaagaaggc tgtgccgttt ttactgcgat
    77401 ttttcctgaa atgtcaataa ttagaggtga attgtcctat tgtcgtccaa tctcttgcta
    77461 aaataactct ttataaaagg caatcgtttc ttctaaggtt ggcataaatg gatttcctgg
    77521 tgcgcaggca tcaatcaagg cattcttaga aaggtattca aagtcgaaat ctttttcttc
    77581 aataccaagt tcagtcagct tcttaggaat acctactgtc tcagaaagct tctcaatctc
    77641 agcaatcgca taatcggcac attcttgatc tgatttacct tctacatgaa gtcccaaggc
    77701 tttggcaaca ttgcggaaag cttctggtac acgtttagca ttttcacgtt ctataactgg
    77761 tagcaacatg gcacagcaaa caccatgtgg caaattatat actgcaccga gttggtgagc
    77821 cattgagtga acataaccaa gaccagcatt attaaagctc ataccaccaa ggaagatggc
    77881 attgaccata ccttcacgcg cttcaatatc atgtccattt tctacagcac gaggaagata
    77941 ttccttgata agctcaatag caccaataga cagtttcttg gttacatcat aagcaccagg
    78001 tgttaccaaa gcttcaacag cgtgagtcag agcatccata ccagtagcag cagtcaggcc
    78061 tttaggtttg gaaagcatga gttccgggtc attaacagag ataagagcaa ggctattctt
    78121 gtcaaccatt accatcttaa ccttgcgttc ttcatcagta atcacatagt taatggtaat
    78181 ttctgctgat gtacctgcag tagtattgat agccacaact ggcaagcctt ttttagcaga
    78241 cttatgaagc ccttcataat cctgtggttt tccaccattt gtagccatga tagaaataca
    78301 actagctgca tcctgtggag aacccccacc aagactgatg ataaaatcac atccatgttc
    78361 ttgcaaagca gctaccccat ctgtgacatt cttacaagta gggtttggct ctacatcgct
    78421 aaagatgaca tattcgattc cttctgtatc cagtggtttt aaaaccttag gtaaaatgtc
    78481 actgccttcg atgtacttat ctgtcaccaa aagtgccttt ttatagccaa gttccttgat
    78541 ataaggaccc acttcattta caacaccttt tccaataagg ttgactgccg gaacataaaa
    78601 tgtagccata taattttcct cctgcgcctc cgcgctatct atttaacatc attatattac
    78661 tttttgtatt cgtttttaat tatttgtgaa ttgtttaaca aatcttttta aaaggatagg
    78721 agggacgtaa gttcacctcc tatataaaca agttttattt atgcagtggt cccaacaact
    78781 gacatgcacg atagtctgct gattctagat cttctgttcc aaataaggac caatttttag
    78841 gtctaaagat atcttcctca ggtacattat gcatattgac aggaattctc aacatagaag
    78901 ccaaggtaat caagtctgct ccaatgtgtc catatgttat ggctccgtga ttagctcccc
    78961 aattattcat gacgtcatag acagacttga aagcaccttt tcctgtcaaa cgtggagcaa
    79021 accaagtagt tggccatcct ggatctgtac gattatctaa agtatggtga acatcttcag
    79081 gaagttcaag tgtataacct tctgcaattt gtagcactgg accaacccct tttagaagat
    79141 tgagacgtac cattgttact ggcatatccc ccttcgtcaa gaaacgagtt gagaatcctc
    79201 ctccacggaa gtattcgcgg tttgctggtg ggaagtctgt attttcaagc atagcctgca
    79261 cttcactttc ttccaactcc cagaagggtt tcataacagg tttgccatct cgagtagctt
    79321 gacctgtacc atccaatgta caagaaccag agttgattag atgtaagaag ccagctgcag
    79381 cacgaccctc taaagtatgt ctcgttacac gtttaacagc ctctggactc caataagtac
    79441 gcacatcagc aaagatttgt ggagtatttg ttaatagata attaaagagc atagacacac
    79501 catttagtga atcattctct gtcgcaaata caaatggttt tcgaatacca ttccagtcaa
    79561 actgagtatt gaggaaagtt tccataaaat ctccatttgg aaaatggtct gtccactgac
    79621 gttgaccttg gaaaccagct actaaagcat ggtgaccaac tgcttcttcc tcaaaaccaa
    79681 gttcagcaag tcttgggtta ccaaccatta agtcacgtcc aatcatgaac atcttaataa
    79741 caaattccca ttgtctatct ttttcttcac ggcttaaaac aaggtcttca cggttatggt
    79801 cgaatccttc ttttacgttt tctttcaccc atttgagcgc acgttcgaac tcttcagggt
    79861 cgtaaatacc acggtccata cggcgtgtga actccgtcat atctaccgat tcatttcgca
    79921 ttcctaagta ttcttggaag aaatccggat ttacaataga accaccaatc cccatcgaaa
    79981 cactacccat tgataggtaa gcagtatctc tcatcaagcc agttgcaaga gctgcacgcg
    80041 cataacgtaa aagtttttct ttgacatctt ctggaatagc tgtgtcacta gcttcctgaa
    80101 catctcttcc ataaatccca aaggctggaa tccctttttg agcatgtgaa gctagtacag
    80161 ctgcaagata gacagctcct gggcgttctg tcccattaaa tccccaaata gcatgaggaa
    80221 tatctggaga catatccata gtttcactac cataacacca gcatggtgta actgtaattg
    80281 ttgcgcaaac atttgatttt ttaaacaact catgggaagc tgcagcctct ggtacacggc
    80341 caatagtaga tggagaaatc acgcattcca caggttcccc atctggatat ttcaatgtgc
    80401 ttgaaatcaa atctgccaca cttttagcca tgttcattgt ttgcacttca agtgattcgc
    80461 gtacaccttg acgacgacca tcaatagtcg gacgaatacc aatacgtgga tgttgaatca
    80521 tactattttc ctcttatttt tctgtttctt tcatactacc atcgccatta tatttacggt
    80581 agcctgggtg ataattttta aaattactta taagtataaa cctctacctc tgctaaactt
    80641 aaaggaattc ctgcgtttct caaagaaatt ctaacctttt ttcccttcag tccttttaag
    80701 tctatggata gattattgct ttctaaactg tcaatatgtt gtgtaaaaac ttcataatca
    80761 tttgaatcat atataataat atcaaaattt gataatctct gaatttcagc atctgttcta
    80821 ttataaataa ttaacttttc taattcttcg gtttgtgcta aatctatctc ccaccatgaa
    80881 ggagaatctt ctttggtatg agtcactgaa tgatgaccat aatctccgtt tttatttcca
    80941 tcaactgcta gacgagaaaa accattgtaa tccgttgaac tctgtcgagt ttcttttgtt
    81001 aatgcaatat tagaaagttt cttcggagtt ctctttgaac catagacttc aacttccgct
    81061 aaacttaacg gaatagctgc tgattttaat tctattttga ctagcttagc ccctacagaa
    81121 ggtactttta aagataacaa accatcaact actttatcaa aatgtcttct aaaaacttct
    81181 tctcctgatg aagatagaaa aataacatca aaattagata aacgctgagg ttcggcatct
    81241 gttctattat aaatatcaac tttagaaacc gtaaactctt ctcccagatc gacctgccac
    81301 caagcgttag aatctgcctt agtatgagtc accgaatgat gtccgtaatc tccatcttta
    81361 ttaccatcaa ctgctaaagc agctacaccc tcataattgg ttgaactttg agtagctacc
    81421 ttatttgtag agactacttt atcttctgtt attttatcta tatcctcttc agattgctta
    81481 ccatctgatt ctctaaaaac ctctacttct gctaaactca aaggcactcc actcgttagt
    81541 aatttaactt taatatacct tgctcctttt tctttgaaat ctagactaac agattcaccc
    81601 gacaaattat taacatgttt cttagcaact tcgtttctat tattgtcata tagaatcaca
    81661 tcaaaattag atagacgttg agtctcagca tctgtgcgat tataaatttt aacaagccca
    81721 actttatcca tttttttcaa atcgacttcc caccaagagg gattatctgc cctagtgtgt
    81781 gttaccgaac cagagttaaa attaccattt ctgttaccat ccacagctct attagggtct
    81841 ccattgtaat ctacagaact ttgtgttgtt ggttttgcat atgctatatt caaattacca
    81901 tcattaaatt tatctggtgt tgggaaagag actggacctg tcccctcagt atttatagac
    81961 atctctacca ttccattatg attaaccgta atggtataaa catgggtatt ctcatcccaa
    82021 ttttctgtat aagtataatg atttttatcg ccacttatat ttatctgagg tttatgacca
    82081 gtatgccctt ttaatgtaag cgttgttgtc ctaaagtcat tatctacagg attgatggaa
    82141 taatttttgc ttatccagtt cgctaactct aattcttctt tcttccaact ttttgatgca
    82201 tcaaaatttc ctgataatgc ccacatagct gtcttatctg tcctgtaatt attcaataaa
    82261 atatgtaaat tatttggatt ttctttaaca acagcgtaag tatgtggcgt caaatctaac
    82321 gataacgact ttgtattatt agtatacata ggcaacatta cttgc
//
LOCUS       DAVKBC010000004        71122 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVKBC010000004 DAVKBC010000000
VERSION     DAVKBC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 71122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71122
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.004"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            89..1114
                     /gene="trpS"
                     /locus_tag="VWX64_000304"
     CDS             89..1114
                     /gene="trpS"
                     /locus_tag="VWX64_000304"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU9189858.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            1266..2744
                     /gene="guaB"
                     /locus_tag="VWX64_000305"
     CDS             1266..2744
                     /gene="guaB"
                     /locus_tag="VWX64_000305"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU9189859.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(2795..3892)
                     /gene="recF"
                     /locus_tag="VWX64_000306"
     CDS             complement(2795..3892)
                     /gene="recF"
                     /locus_tag="VWX64_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU9189860.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(3895..4263)
                     /gene="yaaA"
                     /locus_tag="VWX64_000307"
     CDS             complement(3895..4263)
                     /gene="yaaA"
                     /locus_tag="VWX64_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU9189861.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            4422..5672
                     /locus_tag="VWX64_000308"
     CDS             4422..5672
                     /locus_tag="VWX64_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9189862.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPPLFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            5669..6952
                     /locus_tag="VWX64_000309"
     CDS             5669..6952
                     /locus_tag="VWX64_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9189863.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDCFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESMSQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            6994..7815
                     /locus_tag="VWX64_000310"
     CDS             6994..7815
                     /locus_tag="VWX64_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9189864.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            7826..8371
                     /gene="pgsA"
                     /locus_tag="VWX64_000311"
     CDS             7826..8371
                     /gene="pgsA"
                     /locus_tag="VWX64_000311"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU9189865.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            8368..9195
                     /locus_tag="VWX64_000312"
     CDS             8368..9195
                     /locus_tag="VWX64_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9189866.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPV
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            9180..10019
                     /locus_tag="VWX64_000313"
     CDS             9180..10019
                     /locus_tag="VWX64_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9189867.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            10012..10806
                     /locus_tag="VWX64_000314"
     CDS             10012..10806
                     /locus_tag="VWX64_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9189868.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            10865..11683
                     /gene="mreC"
                     /locus_tag="VWX64_000315"
     CDS             10865..11683
                     /gene="mreC"
                     /locus_tag="VWX64_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU9189869.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVVDIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            11683..12177
                     /gene="mreD"
                     /locus_tag="VWX64_000316"
     CDS             11683..12177
                     /gene="mreD"
                     /locus_tag="VWX64_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU9189870.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            12271..13449
                     /locus_tag="VWX64_000317"
     CDS             12271..13449
                     /locus_tag="VWX64_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU9189871.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAERATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            13673..14452
                     /gene="rpsB"
                     /locus_tag="VWX64_000318"
     CDS             13673..14452
                     /gene="rpsB"
                     /locus_tag="VWX64_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU9189872.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            14531..15571
                     /locus_tag="VWX64_000319"
     CDS             14531..15571
                     /locus_tag="VWX64_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU9189873.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            15817..16140
                     /gene="tnpB"
                     /locus_tag="VWX64_000320"
     CDS             15817..16140
                     /gene="tnpB"
                     /locus_tag="VWX64_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU9189874.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKGFS
                     ITPKI"
     gene            complement(16295..16582)
                     /locus_tag="VWX64_000321"
                     /pseudo
     CDS             complement(16295..16582)
                     /locus_tag="VWX64_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16573..16971
                     /locus_tag="VWX64_000322"
     CDS             16573..16971
                     /locus_tag="VWX64_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9189875.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(17168..18088)
                     /gene="cysK"
                     /locus_tag="VWX64_000323"
     CDS             complement(17168..18088)
                     /gene="cysK"
                     /locus_tag="VWX64_000323"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU9189876.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLVLAPDNGERYLSTALYEL"
     gene            complement(18373..19008)
                     /locus_tag="VWX64_000324"
     CDS             complement(18373..19008)
                     /locus_tag="VWX64_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU9189877.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            19064..20362
                     /locus_tag="VWX64_000325"
     CDS             19064..20362
                     /locus_tag="VWX64_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9189878.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            20359..21021
                     /locus_tag="VWX64_000326"
     CDS             20359..21021
                     /locus_tag="VWX64_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU9189879.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSIKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            21101..21649
                     /gene="raiA"
                     /locus_tag="VWX64_000327"
     CDS             21101..21649
                     /gene="raiA"
                     /locus_tag="VWX64_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU9189880.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            21785..23758
                     /locus_tag="VWX64_000328"
     CDS             21785..23758
                     /locus_tag="VWX64_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU9189881.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFIANFISEFSEKHMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            23755..24207
                     /gene="rplI"
                     /locus_tag="VWX64_000329"
     CDS             23755..24207
                     /gene="rplI"
                     /locus_tag="VWX64_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU9189882.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            24251..25603
                     /gene="dnaB"
                     /locus_tag="VWX64_000330"
     CDS             24251..25603
                     /gene="dnaB"
                     /locus_tag="VWX64_000330"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU9189883.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            25605..25871
                     /locus_tag="VWX64_000331"
     CDS             25605..25871
                     /locus_tag="VWX64_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189884.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            25960..27306
                     /gene="cbpD"
                     /locus_tag="VWX64_000332"
     CDS             25960..27306
                     /gene="cbpD"
                     /locus_tag="VWX64_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU9189885.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      27389..27491
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            27563..27853
                     /locus_tag="VWX64_000333"
     CDS             27563..27853
                     /locus_tag="VWX64_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU9189886.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            27816..28574
                     /locus_tag="VWX64_000334"
     CDS             27816..28574
                     /locus_tag="VWX64_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9189887.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            28613..29620
                     /locus_tag="VWX64_000335"
     CDS             28613..29620
                     /locus_tag="VWX64_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9189888.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            29620..30348
                     /locus_tag="VWX64_000336"
     CDS             29620..30348
                     /locus_tag="VWX64_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189889.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AETISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            30467..30925
                     /locus_tag="VWX64_000337"
     CDS             30467..30925
                     /locus_tag="VWX64_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU9189890.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLVSVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            30927..33359
                     /locus_tag="VWX64_000338"
     CDS             30927..33359
                     /locus_tag="VWX64_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9189891.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVSAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            33680..34333
                     /gene="rr06"
                     /locus_tag="VWX64_000339"
     CDS             33680..34333
                     /gene="rr06"
                     /locus_tag="VWX64_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU9189892.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            34330..35661
                     /gene="hk06"
                     /locus_tag="VWX64_000340"
     CDS             34330..35661
                     /gene="hk06"
                     /locus_tag="VWX64_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU9189893.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLLNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKIPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            35744..36271
                     /locus_tag="VWX64_000341"
     CDS             35744..36271
                     /locus_tag="VWX64_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU9189894.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            36371..36502
                     /locus_tag="VWX64_000342"
                     /pseudo
     CDS             36371..36502
                     /locus_tag="VWX64_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            36549..38666
                     /gene="pspC"
                     /locus_tag="VWX64_000343"
     CDS             36549..38666
                     /gene="pspC"
                     /locus_tag="VWX64_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEU9189895.1"
                     /translation="MFASKSEKKVHYSIRKFSIGVASVAVASLFMGSVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAKKKVEEAKKKAKAQKEEDYRNY
                     PTNTYKTLELEIAEFDVKVKEAELELVKKEADESRNEGTINQAKAKVESEKAEATRLK
                     KIKTDREKAEEEAKRRADAKEQDESKRRKSRVKRGDLGEQATPDKKENDAKSSDSSVG
                     EETLPSPSLKPGKKVAEAEKKVEEADKKAKAQKEEDRRNYPTNTYKTLELEIAESDVK
                     VKEAELELVKEEAKESQNEEKIKQAKAKVESKKAEATRLEKIKTDRKKAEEEAKRKAA
                     EEDKVKEKPAEQPQPAPAPQPEKPTEEPENPAPAPKPEKPAEQPKAEKPADQQAEEDY
                     ARRSEEEYNRLTQQQPPKIEKPAPAPQPEQPAPAPKTGWKQENGMWYFYNTDGSMATG
                     WLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMA
                     TGWLQYNGSWYYLNANGDMATGWFQYNGSWYYLNANGDMATGWLQYNGSWYYLNSNGA
                     MVTGWLQNNGSWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNG
                     SGALAVNTTVDSYRVNANGEWVN"
     gene            complement(38896..39876)
                     /gene="dusB"
                     /locus_tag="VWX64_000344"
     CDS             complement(38896..39876)
                     /gene="dusB"
                     /locus_tag="VWX64_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU9189896.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(39863..40735)
                     /gene="hslO"
                     /locus_tag="VWX64_000345"
     CDS             complement(39863..40735)
                     /gene="hslO"
                     /locus_tag="VWX64_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU9189897.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            40900..42327
                     /locus_tag="VWX64_000346"
     CDS             40900..42327
                     /locus_tag="VWX64_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9189898.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            42486..43994
                     /gene="glpK"
                     /locus_tag="VWX64_000347"
     CDS             42486..43994
                     /gene="glpK"
                     /locus_tag="VWX64_000347"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU9189899.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEIDD"
     gene            44141..45967
                     /gene="glpO"
                     /locus_tag="VWX64_000348"
     CDS             44141..45967
                     /gene="glpO"
                     /locus_tag="VWX64_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU9189900.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARNLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            46037..46741
                     /locus_tag="VWX64_000349"
     CDS             46037..46741
                     /locus_tag="VWX64_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9189901.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            47038..47241
                     /locus_tag="VWX64_000350"
     CDS             47038..47241
                     /locus_tag="VWX64_000350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189902.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(47328..47936)
                     /locus_tag="VWX64_000351"
     CDS             complement(47328..47936)
                     /locus_tag="VWX64_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189903.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            48972..50249
                     /gene="ltrA"
                     /locus_tag="VWX64_000352"
     CDS             48972..50249
                     /gene="ltrA"
                     /locus_tag="VWX64_000352"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEU9189904.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLPTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            50706..51417
                     /locus_tag="VWX64_000353"
                     /pseudo
     CDS             50706..51417
                     /locus_tag="VWX64_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            51612..51862
                     /locus_tag="VWX64_000354"
                     /pseudo
     CDS             51612..51862
                     /locus_tag="VWX64_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
     gene            52176..52307
                     /locus_tag="VWX64_000355"
     CDS             52176..52307
                     /locus_tag="VWX64_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU9189905.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            52328..53878
                     /gene="dltA"
                     /locus_tag="VWX64_000356"
     CDS             52328..53878
                     /gene="dltA"
                     /locus_tag="VWX64_000356"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU9189906.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            53875..55119
                     /gene="dltB"
                     /locus_tag="VWX64_000357"
     CDS             53875..55119
                     /gene="dltB"
                     /locus_tag="VWX64_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU9189907.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            55133..55372
                     /gene="dltC"
                     /locus_tag="VWX64_000358"
     CDS             55133..55372
                     /gene="dltC"
                     /locus_tag="VWX64_000358"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU9189908.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            55365..56633
                     /gene="dltD"
                     /locus_tag="VWX64_000359"
     CDS             55365..56633
                     /gene="dltD"
                     /locus_tag="VWX64_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU9189909.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMRHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            56788..57228
                     /gene="adcR"
                     /locus_tag="VWX64_000360"
     CDS             56788..57228
                     /gene="adcR"
                     /locus_tag="VWX64_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU9189910.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            57228..57932
                     /locus_tag="VWX64_000361"
     CDS             57228..57932
                     /locus_tag="VWX64_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9189911.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            57925..58731
                     /locus_tag="VWX64_000362"
     CDS             57925..58731
                     /locus_tag="VWX64_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9189912.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTISTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            58741..60246
                     /gene="adcA"
                     /locus_tag="VWX64_000363"
     CDS             58741..60246
                     /gene="adcA"
                     /locus_tag="VWX64_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU9189913.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDAKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEIDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(61415..62188)
                     /locus_tag="VWX64_000364"
     CDS             complement(61415..62188)
                     /locus_tag="VWX64_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9189914.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            62364..63767
                     /locus_tag="VWX64_000365"
     CDS             62364..63767
                     /locus_tag="VWX64_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU9189915.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDISVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            63882..64520
                     /locus_tag="VWX64_000366"
     CDS             63882..64520
                     /locus_tag="VWX64_000366"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU9189916.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            64532..64972
                     /locus_tag="VWX64_000367"
     CDS             64532..64972
                     /locus_tag="VWX64_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU9189917.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            64965..65396
                     /locus_tag="VWX64_000368"
     CDS             64965..65396
                     /locus_tag="VWX64_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9189918.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            65387..65857
                     /locus_tag="VWX64_000369"
     CDS             65387..65857
                     /locus_tag="VWX64_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9189919.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            65882..66655
                     /locus_tag="VWX64_000370"
     CDS             65882..66655
                     /locus_tag="VWX64_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9189920.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            66652..67452
                     /locus_tag="VWX64_000371"
     CDS             66652..67452
                     /locus_tag="VWX64_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9189921.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            67511..69805
                     /locus_tag="VWX64_000372"
     CDS             67511..69805
                     /locus_tag="VWX64_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU9189922.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            69815..>71122
                     /locus_tag="VWX64_000373"
     CDS             69815..>71122
                     /locus_tag="VWX64_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189923.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVG"
BASE COUNT        22065 a        11985 c        15586 g        21486 t
ORIGIN      
        1 aaaagcaagg ctgatttatt ttgataaatt acggttattt cattaaaaaa atgctataat
       61 tgaaaggact atatcgaagg agaacaaaat gactaaaccc attattttaa caggagaccg
      121 tccaacagga aaattgcata ttggacatta tgttggaagt ctcaaaaatc gagtattatt
      181 acaggaagag gataagtatg atatgtttgt gttcttggct gaccaacaag ccttgacaga
      241 tcatgccaaa gatcctcaaa ccattgtaga gtctatcgga aatgtggctt tggattatct
      301 tgcagttgga ttggatccaa ataagtcaac tatttttatt caaagccaga ttccagagtt
      361 ggctgagttg tctatgtatt atatgaatct agtttcgtta gcacgtttgg agcgaaatcc
      421 aacagtcaag acagagattt ctcagaaagg atttggagaa agcattccga caggattctt
      481 ggtctatcca atcgctcaag cagctgatat cacagctttc aaggctaatt atgttcctgt
      541 tgggacagat cagaaaccaa tgattgagca aactcgtgaa attgttcgtt cttttaacaa
      601 tgcatataac tgtgatgtct tggtagagcc ggaaggtatt tatccagaaa atgagagagc
      661 agggcgtttg cctggtttag atggaaatgc taaaatgtct aaatcactaa ataatggtat
      721 ttatttagct gatgatgcgg atactttgcg taaaaaagta atgagtatgt atacagatcc
      781 agatcatatc cgcgttgagg atccaggtaa gattgaggga aatatggttt tccattatct
      841 agatgttttt ggtcgtccag aagatgctca agaaattgct gatatgaaag aacgttatca
      901 acgaggtggt cttggtgatg tgaagaccaa gcgttatcta cttgaaatat tagaacgtga
      961 actgggtcct attcgtgagc gccgtattga atttgctaag gatatgggag aagtttataa
     1021 tatgattcaa aaaggtagtg aaagagcgcg tgaagttgcg ggtcaaaccc tatctgaggt
     1081 aaaaggggca atgggacttc attactttaa ctaagtttat tttacaagaa actatcattt
     1141 ctatctcgaa gaaaagatag ttttttattt acccctgtaa catttgacaa atttttatag
     1201 aatggtatga tagatacaat ataaaaagag tcaagctcaa aaagaaagaa aagaggaaac
     1261 ttcgaatgtc taattgggac actaaatttt tgaaaaaagg ttttaccttt gatgatgtat
     1321 tgcttattcc agctgaaagt catgtgttgc ctaacgatgc agatttaaca actaaattgg
     1381 cagataattt gactttaaat atcccaatta ttaccgctgc catggacaca gttacagaga
     1441 gtcaaatggc cattgctatt gctcgtgcag gtggtctcgg agttatccat aaaaacatgt
     1501 caattgctca acaagcagac gaggttcgta aggtaaaacg ttctgaaaat ggagttatta
     1561 ttgatccgtt cttcttgacg cctgaacata caattgctga agcagatgag cttatgggtc
     1621 gttaccgcat cagtggtgtt ccagttgttg aaacacttga aaatcgtaaa ttggttggta
     1681 ttttgacaaa ccgagatctt cgttttattt cagattataa tcaaccaatt tcaaaccata
     1741 tgactagtga aaatcttgtt actgctcctg tgggtacgga tcttgcaacg gctgagagta
     1801 ttcttcaaga gcatcgtatt gaaaaacttc cgttggtcga tgaagaaggc agtctttctg
     1861 gtttgatcac tatcaaagat attgaaaaag ttattgagtt tccaaatgcg gctaaagatg
     1921 agtttggtcg tcttctagtt gcaggtgcag taggtgttac ttcagataca tttgaacgtg
     1981 cagaggctct ttttgaggca ggagcggatg cgattgttat tgatactgca catggtcatt
     2041 ctgcaggtgt cttgcgtaaa attgccgaga ttcgtgctca tttcccagat cggactttga
     2101 ttgctggaaa tattgctact gctgaaggtg cacgtgccct ttatgaagcg ggtgtagacg
     2161 ttgttaaggt tggtattgga ccaggttcta tctgtactac tcgtgtgatt gctggtgttg
     2221 gtgttccgca agtaacagct atctacgatg ctgcagctgt tgcgcgcgaa tatggtaaaa
     2281 cgattattgc tgacggtggg atcaagtatt ctggagatat tgtaaaagca cttgctgcag
     2341 gtggaaatgc tgttatgctt ggatctatgt ttgctggaac tgatgaagct ccaggcgaaa
     2401 ctgaaatctt ccaaggacgt aaattcaaga cttaccgtgg tatgggatca attgctgcta
     2461 tgaagaaagg ttcaagcgac cgttatttcc aaggttctgt caatgaagca aacaagcttg
     2521 ttccagaagg aattgaaggt cgtgttgctt ataaaggagc ggcagctgat attgttttcc
     2581 aaatgattgg tggtattcgc tctggtatgg gttactgtgg tgcagctaac cttaaagaac
     2641 tacacgataa tgctcaattt attgaaatgt ctggtgctgg tttgaaagaa agccatcctc
     2701 atgatgtgca aattactaat gaggcaccaa attattctat gtaaaaaaca atgaaaagaa
     2761 ctccagtgaa aacaggagtt cttttacaat gttgtcaatt tccatttaca gcagctttac
     2821 catcctgaat agtgaagata cttagatttt ctggcagatt ttgaagatgg tctaagcttg
     2881 ttgttgtgat aaaggtttgg attgattgag aaatcgtttc taataatttt aactgtctag
     2941 tgttgtcaag ttcactcatc acatcgtcaa gcagtaatat cggagattct gtggtaatgc
     3001 tttccattaa ttcgatttct gctaatttta tcgagaggac gagactacga tgttgacctt
     3061 ggcttccgaa actagcatcc atcccattta tataaaaaga aatgtcatct cgatgaggac
     3121 cgacaccagt attcttttta aataaatctc tggatctact tttttctaaa gcaattttga
     3181 aagattcgga taagttttgt ttgtcagtta tattgacaga agattgatag gatattgaca
     3241 actcttcgat ctgattagag agttcaaaat gtttcttacg cccaaatgat tctagttttt
     3301 ttatgaaatc taagcggtga ttcattacac gacatccata atcaactagc tgatcatcta
     3361 acacagaaag gaatgtttca tctatttttt gatctgattt taggtaagtg tttctttgct
     3421 ttaggatgtg gttataattg gttaagtcag ataagtagat tggcttaatt tgcccaagtt
     3481 ccatatcaat gaattttcgt cgaatcgaag gtgctccttt aattagttgt aaatcttcag
     3541 gagcaaataa gacaacattc atgtgtccta cataatctga aagtcgtgcc tgttttaagt
     3601 gattaacttt tgttacacgg cctttttgtg ttagttcgat ttctagggga atggatccag
     3661 tttttttctg aacgagacct gaaagatgaa gttgttcttc atcaaaatga atgagatttt
     3721 tatctgttcg agttcgatga ctacgcgtta aggctaaaaa atagatagcc tctaacatgt
     3781 ttgtttttcc ttgtgcatta cgtcccaaaa agacattcaa tttaggatta aagtctattt
     3841 tcgtttcttt gtaattacga aaagtcttga gagatagatg ttgtagccac atgattatct
     3901 accagggaat cgtggagctt gttggctttt aggtgatgaa gcaggtttcg atttgtcttt
     3961 tttaactccc ttattcatct ttttgacaag tttagcgatc cgttcttttt caactttatc
     4021 agcttggtat tcatcttgtt cttcagaagt aggttgtgtc aacaagatgt caatgttcat
     4081 gtcagggatg tcaactttat cgccaatacg aagttttttt ccacgacgac tctctaattc
     4141 cctattaaag taaacagaat gttcagagag aaatgattta atagctcctc cgctatgtgt
     4201 aattccaagt tctttgagta gtgcttggag ggtaataaat tcttcaaata atttgtattc
     4261 cataattcac ctcaatcttt ggtattatac catattttcc taaaaatagt gagagagaca
     4321 gagagaaatg taagcgattt ttatttcaaa agtgttacag ggaacaagaa aatttcaggt
     4381 tttcgtgata taatagaagt ctgtatataa ggaggtaaat catggagtta gtgcatggaa
     4441 tttcaacaca ttttatccaa tcaaaaaagt ttaaaacaaa caaaattacc gtgcgtttta
     4501 ccgctccatt atcccttgat acgattgcag gtcacatgtt gagtgcaagt atgctagaga
     4561 ctgctaatca gatgtacccc acttctcaag atttgaggag acacttggcc agtctatacg
     4621 gtacagatat gtcaaccaat tgtttcagaa gagggcaaag ccacattata gaattgacat
     4681 ttacctatgt tcgtgatgag tttttaagta ggaaaaacgt gctaacctct cagattttgg
     4741 aacttgtaaa agaaactctt ttttcacccg tagtagttga taatgggttt gatccgccct
     4801 tatttgaaat tgagaaaaaa caattgctag caagtttagc agctgatatg gatgattctt
     4861 tttattttgc acataaagaa ttggataaat tgttttttca tgatgaacgt cttcaattgg
     4921 aatatagtga tttacgaaat cgtattttag ctgaaactcc acaaagttct tattcttgtt
     4981 tccaagaatt tttagccaat gatcgaatag atttcttttt cctaggtgat tttaatgagg
     5041 ttgaaattca aaatgtatta gaatcatttg gctttaaagg tcgaaaagga gatgtgaagg
     5101 ttcagtattg tcaaccttat tctaatatcc ttcaggaagg tatggttcgg aaaaatgtgg
     5161 gacaatccat tttggaatta ggttatcatt accgttctaa atatggtgat gagcaacatt
     5221 tacccatgat tgtaatgaat ggtttacttg gtggatttgc tcactctaag ctctttacaa
     5281 atgtccgtga aaatgctgga ttagcttata ccatttcaag tgagcttgat ttatttagtg
     5341 gattcttgag gatgtatgct ggtatcaatc gagaaaatcg taaccaggct cgtaaaatga
     5401 tgaataatca actgcttgat ttaaaaaaag gttattttac agagtttgag ttaaatcaga
     5461 ccaaggaaat gattcgttgg tcgttgttac tttctcaaga taatcaatct tcattgattg
     5521 aacgtgctta tcaaaatgcc ttatttggaa aatcttcagc agactttaaa agttggattg
     5581 caaagcttga acaaattgac aaagatgcta tttgtagagt agctaataat gtgaaactac
     5641 aagcgattta ctttatggaa ggaatagaat gacaaaggtt gtttttgaag aaaaatacta
     5701 tccagctgta aaagaaatgg tttatcgaac tcgtttggcc aacggattga cagttgctct
     5761 tttgcctaaa aaggaattta aagaggttta cgggagtgtc actgtacagt ttggttcggt
     5821 agatacgttt gtcacagaag ttgacggaga tgtaaaacaa tatcctggag gaattgctca
     5881 ttttcttgaa cataaattat ttgagagaga agattctagt gatttgatgt cggcttttac
     5941 gagtctaggt gcagatagta atgcctttac aagctttaca aaaacaaact atcttttttc
     6001 agcaacggat tgttttttag aaaatttaga tttacttgat gaattggtaa catcagcaca
     6061 ctttactgaa gcttccattc tgacagagca ggatattatt cagcaagaac gagaaatgta
     6121 ccaagatgat ccagattcgt gtttattctt ttcaacttta gcgaatttgt atcctggtac
     6181 acctttagca actgatatag ttggaagtga ggagtccatg tcccaaatca atctaactaa
     6241 tttgcaagaa aattttacaa agttttacaa acctgtaaac atgtctctgt ttttagttgg
     6301 taattttgat gtggagcgag tacaggacta ttttgaaagc aaagaactga aagattcaga
     6361 ttttcaggaa gtagcaagag aaaagttgtt tttacagcct gtaaagccaa cagatagtat
     6421 gagaatggaa gtatcttctc ccaaactagc gattggagtt agaggtaagc gagaagtttc
     6481 tgaagcggat tgctatcgac atcatatttt attaaaatta ttgtttgcaa tgatgtttgg
     6541 ttggacttcg gatcgttttc aaaaatgtta tgaatcaggt aaaattgatg cgtccttatc
     6601 tctggaagtt gaaataacaa gtcgctttca ttttgtcatg ttgacaatgg atacgaaaga
     6661 gccagttgct ttgtctcatc aatttaggaa ggctattcgt aattttacaa aggatttaga
     6721 tattacagag gaacatttag atattatcaa aagagagatg tttggcgaat ttttcagtag
     6781 catgaactct cttgaattta ttgcaacgca atatgatgct tttgaaaatg gtgagacaat
     6841 ttttgatttg ccgaaaattt tacaggaaat tactttagag gatgtccttg atgctggaca
     6901 tcatttaata gatgatggtg acatagttga ttttacaata ttcccatcgt agtaacctat
     6961 cataatagac actagaaaga agggatgaca agtatgagaa aaaaaacaat tggagaggtt
     7021 ttacgattag ctagaatcaa tcagggattg agtttagatg aattgcagaa aaagacagaa
     7081 atccagttag atatgttgga agcaatggaa gcagacgatt tcgatcaact tccaagtcct
     7141 ttttacacgc gttctttctt gaaaaaatat gcatgggctg ttgagttaga tgaccaaatt
     7201 gttttggatg cttatgattc tgggagtatg attacttatg aggaagtaga tgttgatgaa
     7261 gatgagttga caggtcgtag acgttcaagt aagaaaaaga agaaaaaaac atcattttta
     7321 cctttatttt attttatcct ttttgcttta tcgattttaa tttttgtgac ttattatgtt
     7381 tggaactata ttcaaactca accagaggag ccttctcttt ctaattacag tgtggttcaa
     7441 tcaacaagtt caactagctc tgttccccac tcctcaagta gtagttcttc tagtatagaa
     7501 tcagctataa gtgtatcagg cgaaggaaat catgtagaaa tcgcttataa gacaagtaag
     7561 gaaacagtta aattgcaatt ggcagtttca gatgttacaa gttgggtcag tgtttcagaa
     7621 agcgaacttg agggcggtgt aaccttatcg ccaaagaaga aaagtgcaga agcaacagtt
     7681 gcaactaaaa gtcctgtaac aattacgtta ggtgttgtaa aaggtgttga tttgacagta
     7741 gataatcaga ctgttgattt atcgaaatta acagctcaga ctggacaaat cactgtaacc
     7801 tttactaaaa attaaggaaa aacgaatgaa aaaagaacaa attcccaatc tcttaacaat
     7861 aggtcgaatt ctctttatac ctatttttat ctttatttta acgataggaa attcgataga
     7921 gagtcatata gttgcagcta ttatctttgc tgttgccagt attaccgact atttagatgg
     7981 atatttagct cgtaaatgga atgtggtcag taattttggt aaatttgcag atcctatggc
     8041 ggataagtta ctagttatgt cggcttttat tatgttgatt gagttaggta tggctccggc
     8101 ttggattgtt gcagtgatta tctgtcgtga gttagctgtg acaggtttaa ggcttttatt
     8161 ggttgaaact ggtggaacaa ttttagcagc agcaatgcct ggaaaaatta aaacttttag
     8221 tcagatgttt gccattattt tcttgctatt acattggact ttgcttggtc aagttctact
     8281 ttatgtagcc ttatttttca ctatctactc tggctatgac tatttcaagg gtagtgccta
     8341 tgtatttaaa gggacatttg gttcgaaatg aaatcaataa ttgatgtaaa aaatctttct
     8401 tttcgctata aagaaaatca gaactactac gatgtgaagg atattacgtt tcacgtgaaa
     8461 cgtggagaat ggctttcgat tgtagggcat aatggtagtg gtaaatcaac gacggttcga
     8521 ttaattgatg gcttactgga agcagaatcc ggagagattg taattgatgg ccaacgtttg
     8581 actgaggaaa atgtttggaa tatacgtcgt caaatcggta tggtttttca aaatccagac
     8641 aatcaatttg ttggagcgac tgttgaagat gatgttgctt ttggtttgga aaatcaggga
     8701 ctttctcgtc aagaaatgaa aaagagagtg gaagaagctc tggctttagt tggcatgttg
     8761 gactttaaaa agagagagcc agcgcgtcta tcaggtggcc aaaagcaacg tgtggccatt
     8821 gcaggtgttg tagccctaag accagttatt ttaatcttag atgaagcaac gagtatgttg
     8881 gatcctgagg ggcgtagaga acttattggg acagtaaaag gaattcgaaa agactatgat
     8941 atgacggtca tttctattac ccatgatttg gaagaagtcg ccatgagtga tcgcgtattg
     9001 gtcatgaaaa aaggggaaat tgaatcaact agtagtccaa gggagctttt ctctcgaaat
     9061 gatttagatc aaattggatt agacgatcct tttgctaatc aattaaaaaa atctttgagc
     9121 cagaatggct atgatttacc tgaaaattat ttgacagaaa gtgagctaga ggataagcta
     9181 tgggaattgc tctagaaaat gtgaatttta catatcaaga aggtactccc ttagcttcag
     9241 cagctttgtc ggatgtttct ttgacgattg aagatggctc ttatacagct ttaattgggc
     9301 acacaggtag tggtaaatca actattttac aactcttaaa tggtttattg gtgccaagtc
     9361 aagggagtgt gagggttttt gataccttaa tcacctcgac ttctaaaaat aaagatattc
     9421 gtcaaattag aaaacaggtt ggcttggtat ttcagtttgc tgaaaatcag atttttgaag
     9481 aaacggtttt gaaggacgtt gcttttggac cgcaaaattt tggagtttct gaagaagatg
     9541 ctgtgaagac tgcgcgtgag aaactggctc tggttggaat tgatgaatca ctttttgatc
     9601 gtagtccgtt tgagctgtca gggggacaaa tgagacgtgt tgccattgca ggcatacttg
     9661 ccatggagcc agctatatta gtcttagatg agccaacagc tggtctagat cctctaggga
     9721 gaaaagagtt gatgaccctg ttcaaaaaac tccaccagtc agggatgacc atcgtcttgg
     9781 taacgcattt gatggatgat gttgctgaat atgcaaatca agtctatgta atggaaaagg
     9841 gacgtttagt aaaggggggc aaaccaagtg atgtctttca agacgttgtt tttatggaag
     9901 aagttcagtt gggagtacct aaaattacgg ccttttgtaa acgattggct gatagaggcg
     9961 tgtcatttaa acgattaccg attaagatag aggagttcaa ggagtcgcta aatggatagt
    10021 atgattttgg ggcgttatat cccaggggat tcgattgttc accgattgga tccacgtagc
    10081 aaattgcttg ctatgatgct actgattttg attgtgtttt gggctaataa ccccttgacg
    10141 aatctgattc tttttatagc gacagggata tttattgcct tgtcaggagt atctctttca
    10201 ttttttattc agggcttgaa gtctatgttt ttcttgattg ccttcacaac tatttttcaa
    10261 ctatttttca tttctaatgg gaatgtttta tttgagtttt cgtttgtgag aatcacggat
    10321 tatgctttgc aacaagctgg gattattttt tgtcgctttg tattgattat tttcttttca
    10381 actttgttaa ccttaacaac catgccttta agtttggcat cagctgtcga agctttatta
    10441 gcacctttaa agcgtgtgaa agttccagtt catgaaattg gattgatgct gtctatgagt
    10501 ttgcgttttg tcccaacctt gatggatgat acgactcgga ttatgaatgc acagaaagct
    10561 cgtggagtgg attttggaga aggaagcatc gttcaaaaag taaaggcgat gattcccatt
    10621 ttgattcctc tttttgcgac aagtttaaaa cgtgcagatt ccttggctat cgctatggaa
    10681 gcgcgtggct atcagggtgg aaaaggcaga agtcaatacc gacaattgaa atggactcta
    10741 aaggatacgc tgaccattct tgttattctc gtacttggtt gttgtttatt tttcttaaaa
    10801 tcttagtagc tttcaggaat tgataaaaag ttactgtaac agtttttgat ataaaggtag
    10861 ggatatgaac cgttttaaaa aatcaaaata tgtcattatt gtttttgtca ctgttctgct
    10921 tgtgtcagct ctcttagcga cgacttattc aagtacaatt gtgacaaaat taggagatgg
    10981 aatctcattg gttgatagag ttgtacaaaa accttttcag tggtttgatt ctgtcaaatc
    11041 agatttggct catttgacac gaacatataa tgaaaatgaa agtttgaaga aacagcttta
    11101 ccaattagaa gttaaatcaa atgaggtgga aagtttaaag acagaaaatg aacaactgcg
    11161 ccaattgctt gatatgaagt ctaaattgca agccacaaag actttagcag cagatgttat
    11221 tatgcgttct ccggtatctt ggaagcagga gttgacctta gatgcaggta gatcaaaagg
    11281 tgcttctgag aacatgttag ctattgcaaa tggtggcttg attgggagtg tttcaaaagt
    11341 agaggagaac tctactatag tcaaccttct gacaaatacg gaaaatgctg ataagatttc
    11401 tgttaaaatt caacatggct ctactacaat ttatggaatt attattggct atgacaagga
    11461 aaatgacgtt cttaaaatta gccaattaaa tagtaatagc gatattagtg cgggagataa
    11521 ggtgactact ggtggattag gaaactttaa cgttgttgat attcctgttg gtgaagtggt
    11581 tgccacaacg catagtacag actatttgac acgagaagta actgttaaat tgagtgcaga
    11641 tactcataat gtagatgtga tagaattagt ggggaattca taatgagaca gttgaagcga
    11701 gttggagtat ttttattgct tcctttcttt gttctaattg acgcccatat tagccagctt
    11761 ctgggctcat ttttccccca tgtacatttg gctagtcatt ttctttttct atttctctta
    11821 tttgagacga tagaagtatc agagtatctc tacctagtct attgttttgt tataggcttg
    11881 gtttatgatg tttacttttt ccatctaata gggattacaa ctctcttatt tatcttattg
    11941 ggagccttcc ttcataaatt gaatagtgtt attttgttga atcgttggac aagaatgcta
    12001 gctatgattg tgctgacatt cctgtttgaa atgggtagtt atcttttggc ttttatggta
    12061 gggttgacag tagatagcat gtcgattttt atagtctata gcttggtacc gacgatgatt
    12121 ttaaattttt tatggattac tgtttttcaa tttatttttg aaaaatatta tctataagaa
    12181 cgacatataa atgtaacaaa ggcgtaatat ttattaggcc tttttttggt atactagtat
    12241 tgtctttaaa agaaggagta tctacgtaat atgaagaaaa aaatcttagc gtcactttta
    12301 ttaagtacag taatggtttc tcaagtagct gttttaacaa ctgcgcatgc agaaacgact
    12361 gatgacaaaa ttgctgctca agataataaa attagtaact taacagcaca acaacaagaa
    12421 gcccaaaaac aagttgacca aattcaggag caagtatcag ctattcaagc tgagcagtct
    12481 aacttgcaag ctgaaaatga tagattacaa gcagaatcta agaaactcga gggtgagatt
    12541 acagaacttt ctaaaaacat tgtttctcgt aaccaatcgt tggaaaaaca agctcgtagt
    12601 gctcaaacaa atggagccgt aactagctat atcaatacca ttgtaaactc aaaatcaatt
    12661 acagaagcta tttcacgtgt tgctgcaatg agtgaaatcg tatctgcaaa caacaaaatg
    12721 ttagaacaac aaaaggcaga taaaaaagct atttctgaaa aacaagtagc aaataatgat
    12781 gctatcaata ctgtaattgc taatcaacaa aaattggctg atgatgctca agcattgact
    12841 acgaaacagg cagaactaaa agctgctgaa ttaagtcttg ctgctgagag agcgacagct
    12901 gaaggggaaa aagcaagtct attagagcaa aaagcagcag ctgaggcaga ggctcgtgca
    12961 gctgcggtag cagaagcagc ttataaagaa aaacgagcta gccaacaaca atcagtactt
    13021 gcttcagcaa acactaactt aacagctcaa gtgcaagcag tatctgaatc tgcagcagca
    13081 cctgtccgtg caaaagttcg tccaacatac agtacaaacg cttcaagtta tccaattgga
    13141 gaatgtacat ggggagtaaa aacattggca ccttgggctg gagactactg gggtaatgga
    13201 gcacagtggg ctacaagtgc agcagcagca ggtttccgta caggttcaac acctcaagtt
    13261 ggagcaattg catgttggaa tgatggtgga tatggtcacg tagcggttgt tacagctgtt
    13321 gaatcaacaa cacgtatcca agtatcagaa tcaaattatg caggtaatcg tacaattgga
    13381 aatcaccgtg gatggttcaa tccaacaaca acttctgaag gttttgttac atatatttat
    13441 gcagattaat ttacagaggg actcgaatag agccctcttt tcaggtttta ccgtgacaat
    13501 ccctattaaa aattatatca aaatagcttg aaaatattgg aaaagtatgg tagaatgaaa
    13561 attgtcgtgt gaacgataat actcattctt gatgaattgt gaagcagttg cccttgggtc
    13621 gttttgcgag ttgaagtcaa gaagaggaaa aaaacaaaaa ggagaaatac tcatggcagt
    13681 aatttcaatg aaacaacttc ttgaggctgg tgtacacttt ggtcaccaaa ctcgtcgctg
    13741 gaatcctaag atggctaagt acatctttac tgaacgtaac ggaatccacg ttatcgactt
    13801 gcaacaaact gtaaaatacg ctgaccaagc atacgacttc atgcgtgatg cagcagctaa
    13861 cgatgcagtt gtattgttcg ttggtactaa gaaacaagca gctgatgcag ttgctgaaga
    13921 agcagtacgt tcaggtcaat acttcatcaa ccaccgttgg ttgggtggaa ctcttacaaa
    13981 ctggggaaca atccaaaaac gtatcgctcg tttgaaagaa attaaacgta tggaagaaga
    14041 tggaactttc gaagttcttc ctaagaaaga agttgcactt cttaacaaac aacgtgcgcg
    14101 tcttgaaaaa ttcttgggcg gtatcgaaga tatgcctcgt atcccagatg tgatgtacgt
    14161 agttgaccca cataaagagc aaatcgctgt taaagaagct aaaaaattgg gaatcccagt
    14221 tgtagcgatg gttgacacca atactgatcc agatgatatc gatgtaatca tcccagctaa
    14281 cgatgacgct atccgtgctg ttaaattgat cacagctaaa ttggctgacg ctattatcga
    14341 aggacgtcaa ggtgaggatg cagtagcagt tgaagcagaa tttgcagctt cagaaactca
    14401 agcagattca attgaagaaa tcgttgaagt tgtagaaggt gacaacgctt aatttataca
    14461 aatagtaatt acctaggagg gcggggctta gcccggctct cctattttca aaaaatatag
    14521 gagaattaaa atggcagaaa ttacagctaa acttgtaaaa gagttgcgtg aaaaatctgg
    14581 tgccggtgtt atggacgcta aaaaagcgct tgtagaaaca gacggtgaca tcgaaaaagc
    14641 gattgaattg cttcgtgaaa aaggtatggc taaggcagct aagaaagctg accgtgttgc
    14701 tgcagaaggt ttgactggtg tttatgttaa cggtaatgtt gcagcagtta ttgaagtaaa
    14761 cgctgaaact gacttcgttg caaaaaacgc tcaattcgtt gaattggtaa atactacagc
    14821 taaagtcatt gctgaaggaa aacctgctaa caatgaagaa gctcttgctt tgataatgcc
    14881 ttcaggtgaa actcttgaag ctgcatacgt atctgcaaca gcaactatcg gagagaaaat
    14941 ctcattccgt cgctttgcat tgattgaaaa aacagacgca caacactttg gagcatacca
    15001 acataacggt ggacgtatcg gtgttatttc agttgttgaa ggtggagacg aagcacttgc
    15061 taaacaattg tcaatgcaca tcgcagcgat gaaaccaaca gttctttctt acaaagaatt
    15121 ggatgagcaa ttcgttaaag atgagttggc acaattgaat cacgttatcg accaagacaa
    15181 cgaaagccgt gcaatggtta ataaaccagc tcttccacac ttgaagtatg gatcaaaagc
    15241 tcaattaact gatgatgtta ttgctcaagc tgaagctgac atcaaagctg aattggctgc
    15301 agaaggcaaa ccagaaaaaa tctgggacaa aattattcca ggtaaaatgg atcgcttcat
    15361 gcttgataac actaaagttg accaagctta cacacttctt gcacaagttt acatcatgga
    15421 tgacagcaag acagttgaag cataccttga atcagttaac gcttcggtag ttgagtttgc
    15481 tcgctttgaa gttggtgaag gtatcgagaa agctgcaaac gacttcgaag ctgaagttgc
    15541 agctacaatg gcagcagcct tgaataacta ataatagaaa ggaagcaatt tgcttccttt
    15601 tttgtatagg gcttatattt ttcctgaaat tgtttttcct ccagtctcac tcgattagaa
    15661 taattaaaac aaaaagccct ataataaggg ctaagtgcat ttaggagact atacttcaaa
    15721 ttcatagtaa gcgcgtcata acaaggtatc tatcctaatt ccccaacttc cagtatacta
    15781 gataaaaaat aattatcgga ggaaaggtat tgtactatga tgattcaact aagtgattta
    15841 ggtcaagttc acattgtttg tggcaagaca gatatgaggc agggaataga ctcattagcc
    15901 tatgtagtta aaacccactt tgaattggat tctttctccg gtcaagtctt tctcttttgt
    15961 ggtggacgta aagaccgctt taaagtcctt tactgggatg gtcaaggatt ttggctacta
    16021 tataaacgct ttgagaacgg aaaactgact tggctaagta cagaaaagga tgtcaaagct
    16081 ctcacatctg aacaagtaga ttggcttatg aagggctttt ctatcactcc aaaaatatag
    16141 tagattgaaa ctagaatagt acacctctgc ttctaaaata ttgttagaaa tcgatttgat
    16201 tgtcctgatc gatttgtcct gttcttattt cattttacta taaatccatc agaaagttgt
    16261 gatttctatt gaaatgagga ctttcttttt acactcatct gctttcaaaa agcattctag
    16321 tccatctccg attaacgatg gactttatca cctccttctc cagtccttgt atgacatctt
    16381 ccaaagttcg aaaggcttta ttcttaaatc cacgtttacg aatctctttc cacacttgtt
    16441 caatggggtt catctctggt gtgtatggag gaataaatgc aaagccaata ttagtcggaa
    16501 tctttaaggt acttgattta tgccatatag cattgtccat aacgagtaaa agataatcat
    16561 ctggataagc ttgtgaaagc tcctattcct aaagcccctt tagcgcatag ctttggctca
    16621 gcttctatta tcgctcacac catccatcag aagtttaatc tgaaggtacc caattatcgc
    16681 caagaagaag attgggctaa gatgggttta ccaatcacac gcaaggaaat ctctaattgg
    16741 catatcaaga cgagtcaata ctatttggag cccctctata acctcttgcg agagagacta
    16801 ttgactcagc ccttacttca tgcggatgaa acttcttata gggtgctaga gagtgatagt
    16861 cagctgactt actattggac ttttttgtct gggaaagctg agaaacaagg gattacgctt
    16921 taccatcatg tcctaatcga tttgttcata tcttatttca atccattata aatagtgaga
    16981 aatatctatc ctatcttcta gaatgtcttc caaacgtgga aactctcgta aacaaagagg
    17041 ttttagaggc ttatttacca tggactaaag ttgtacaaga aaagtgcaaa taagaaatct
    17101 ccagattagg aactatccgt gagttctcta gtctggagat ttttcaatat acttcgttat
    17161 tggacggtta caattcataa agtgctgtag agagataacg ttcaccgtta tctggtgcta
    17221 ggacaaggac ttttttacct gtacctaatt ttttggcaac ctcgatggct ccgtagatag
    17281 ctgcagctga ggaaatccct acaaggaagc cttcttttcc accaatttca cgtccgagtg
    17341 caagagcgtc atctgatgtt acacgaacga taccatcata ggctttagta tcaagtgtat
    17401 caggaataaa tccagctgag ataccttgaa ttttgtgagg accaggtttt tcaccagata
    17461 gaatagcaga ttcatctgct tctactgcaa aaacttgaat gttagaattt tctgatttga
    17521 gtgcatgaga aacaccagaa atcgttccac cggtacctac tccagcaaca aaggcatcta
    17581 atccatcttt accgaaagca gctagtatct cagctcctgt tgttctttcg tgtacttctg
    17641 gattagctgg attgtcaaat tgaagaggaa ggaaaccatc acgttcagca gcgatttctt
    17701 gagccttagc aatagcacct ttcattccct cgctaccagg agttaggacg agttcagcac
    17761 cataagcttg gataatttta cgtcgttcta cactcatagt ttcaggcata acgatgacga
    17821 ctttataccc tttagcagca cctacccatg aaagtccaat accagtgttt ccacttgttg
    17881 cttcaacaat agtagaacca ggtttcagaa taccatcttg ttcagctttt tcaatcatgc
    17941 taagggcaat acggtctttt acagatgaac caggattaaa tgcttcaagc tttatataga
    18001 cgtctgcagc accttctggc acgatgttgt taagtttaac aatcggtgtt tgaccgatta
    18061 attcagtaat gttgttataa atagacatat gaatacctct ttgtataaga tatctttagt
    18121 ataacgctat ctataccatt tgtaaaatat agaaatccta tcgaagcgat aggatttcta
    18181 tatatcatag atcaaagtca ttaattttca agtgattgcg ttcagctaat tctagtaaat
    18241 aggtgtgaag gaaaacgata tcaggtttcg tttgaattgc ttcattttct agtatatttt
    18301 ggtacgcatc tttttatttt gctcgctaaa gtagttgtga gaatgtcaac gaaacgctgt
    18361 attattcatt gtttacacta agtttacagg aacttcaacc tctcgtaaac cttggtcagt
    18421 taaagtgact tttccattaa aaaactccac aagtgcagct ttaatagttt ctttttcttc
    18481 cttatcaaca taaatcatcg tatcgacttg atctgtaaag tttgtatcca gctccatgag
    18541 atcatgttct ttaaggaagt tactgtactc ttggtactga gcataagaca tttgaatagc
    18601 aatgccagcc tgttctttta tttcaataat accaatttct ttgacagcta aggcgacact
    18661 gccggcgtaa gcacgaatta gtcctccagc gcctagttta ataccaccaa agtagcgtgt
    18721 cacgaccaca cagacattgg tgagattgtg attttctagt accccaagca tgggaacacc
    18781 agcagtacca ctaggctcac catcatcact tgtacgttta atttcactac gttctccaat
    18841 aataaaggca gagcagttat gtgtcgcttt gtagtgttct tttttgatgg cagtaatgaa
    18901 gtcacgagcc tcttcttcgc tataaacacg cttggcatgg cagataaagc gagatttttt
    18961 gatttcttct tggacttggc cgtcctcttt aattgtccta aattccatga tttaattgta
    19021 ctaaaaaata atctaaagtg ctagttttta cgaataaaga agtatgaaag taaatttaga
    19081 ttatctcggt cgtttattta ctgagaatga attaacagaa gaagaacgtc agttggcgga
    19141 gaaacttcca gcaatgagaa aggagaaggg gaaacttttc tgtcaacgtt gtaatagtac
    19201 tattctagaa gaatggtatt tgcccatcgg tgcttactat tgtcgagagt gcttgctgat
    19261 gaagcgagtc agaagtgatc aaactttata ctattttccg caggaggatt ttccgaagca
    19321 agatgttctc aaatggcgcg gccaattaac tccttttcaa gagaaggtgt cagagggact
    19381 gcttcaagca gtagacaagc aaaagccaac cttagttcat gcggtaacag gagctggaaa
    19441 gacagaaatg atttatcaag tagtggctaa agtgatcaat gcgggtggtg cagtgtgttt
    19501 ggctagtcct cgcatagatg tttgtttgga gctgtacaag cgcctgcaac aggatttttc
    19561 ttgcgggata gctttgctac atggagaatc ggaaccttat tttcgaacac cactagttgt
    19621 tgcaacaacc catcagttat tgaagtttta tcaagctttt gatttgctga tagtggatga
    19681 agtagatgct tttccttatg ttgataatcc cacgctttac cacgctgtca agaatagtgt
    19741 aaaggagaat ggattgagaa tctttttaac agcgacttcg accaatgagt tagataaaaa
    19801 ggtccgttta ggagaactaa aaagactgag tttaccgaga cggtttcatg gaaatccgtt
    19861 gattattcca aaaccaattt ggttatcgga ttttaatcgc tacttagaca agaatcgttt
    19921 gtcaccaaag ttaaagtcct atattgagaa gcagagaaag acagcttatc cgttactcat
    19981 ttttgcttca gaaattaaga aaggggagca gttagaagaa atcttacagg agcaatttcc
    20041 aaatgagaaa attggctttg tatcttctgt aacagaggat cgattagagc aagtacaagc
    20101 ttttcgagat ggagaactga caatacttat tagtacgaca atcttggagc gtggagttac
    20161 cttcccttgt gtggatgttt tcgtagtaga ggccaatcat cgtttgttta ccaagtctag
    20221 tttgattcag attggtggac gagttggacg aagcatggat agaccgacag gagatttgct
    20281 tttcttccat gatgggttaa atgcttcaat caagaaggcg attaaggaaa ttcagatgat
    20341 gaataaggag gctggtctat gaagtgcttg ttatgtgggc agactatgaa gactgtttta
    20401 acttttagta gtctcttact tctgaggaat gatgactctt gtctttgttc agactgtgat
    20461 tctacttttg aaagaattgg ggaagagaac tgtccaaatt gtatgaaaac agagttgtca
    20521 ataaagtgtc aagattgtca actttggtgt aaagagggag ttgaagtcag tcatagagcg
    20581 atttttactt acaatcaagc tatgaaggat tttttcagtc ggtataagtt tgatggagac
    20641 ttcctgttaa gaaaagtttt cgcttcattt ttaagtgagg agttgaaaaa gtacaaagag
    20701 tatcaatttg ttgtaattcc cctaagtcct gatagatatg ctaatagagg atttaatcag
    20761 gttgagggct tggtagaggc agcaggcttt gagtatctgg atttattaga gaaaagagaa
    20821 gagagagcca gttcttctaa aaatcgttca gagcgcttgg ggacagaact tcctttcttt
    20881 attaaaagtg gagtcactat tcctaaaaaa atcctactta tagatgatat ctatactaca
    20941 ggagcaacta taaatcgtgt taagaaactg ttggaagaag ctggtgctaa ggatgtaaaa
    21001 acattttccc ttgtaagatg aggaaaaaat ttgcaaaaat agaatgaaag cgttataata
    21061 aaatcataaa aacaaaaatg tttagaaaga aggtactcat atgattaaat atagtatccg
    21121 tggtgaaaac ctagaagtaa cagaagcaat tcgtgattat gtagtttcta aactcgaaaa
    21181 gatcgaaaag tacttccaac cagaacaaga gttggatgcc cgaattaact taaaagttta
    21241 tcgtgaaaaa acggctaaag tggaagtaac gattccgctt ggatctatta ctctccgcgc
    21301 agaagatgta tctcaagata tgtatggttc aattgacctt gtaactgata aaattgaacg
    21361 tcagattcgt aaaaataaaa caaaaatcga gcgtaaaaat aaaaataagg tagcaactgg
    21421 tcaattattt acagatgctt tggtggaaga ttcaaatgtt gtccagtcta aagttgttcg
    21481 ttcaaaacaa attgatttaa aaccaatgga tttggaagaa gcaattctac aaatggattt
    21541 attggggcat gatttcttta tctatgtgga tgttgaagat cagacaacca atgtgattta
    21601 tcgtcgtgag gatggcgaaa ttggtttgtt agaggttaaa gaatcttaat ttcaatatgt
    21661 gtaaaggtag gtttactgaa ttgtaaacta cctttttctt ataattgata gaattactga
    21721 ttacactttt aaaaagtcgc tttttgaggg gtattatggt ataatgggtg ccaagaggtt
    21781 ttgaatgaaa aaattttatg taagtccaat ttttcctatt ctagtaggat tgattgcgtt
    21841 tggagtctta tccactttca ttatttttgt taataataat ctgttgacgg ttttaatttt
    21901 gtttcttttt gtaggaggct atgttttttt atttaagaaa ctgagagtgc attatacaag
    21961 gagtgatgta gaacagatac agtatgtaaa ccaccaagcg gaagaaagtt tgacatctct
    22021 attggaacaa atgcctgtag gtgttatgaa attgaattta tcttctggag aggttgagtg
    22081 gtttaatccc tatgctgaat tgattttgac caaggaagat ggtgattttg atttagaagc
    22141 tgttcaaacg attatcaagg cttcagtagg aaatccgtct acttatgcca agcttggtga
    22201 gaagcgttat gctgttcata tggatgcttc ttccggtgtt ttgtattttg tagatgtatc
    22261 cagggaacaa gccataacag atgaattggt aacaagtcga ccagtgattg ggattgtctc
    22321 tgtggataat tatgatgatt tggaggatgc aacttctgag tcagatatta gtcaaatcaa
    22381 tagttttata gctaatttta tatcagagtt ttcagaaaaa cacatgatgt tttctcgtcg
    22441 ggtaagtatg gatcgatttt atctatttac tgactacacg gtgcttgagg gcttgatgaa
    22501 tgataaattt tctgttattg atgctttcag agaagagtcg aaacagagac agttgccctt
    22561 gaccttaagt atgggatttt cttatggcga tggaaatcat gatgagatag ggaaagttgc
    22621 tttgctcaat ttgaacttgg ctgaagtacg tggtggcgac caggtggttg ttaaggaaaa
    22681 cgacgaaacg aaaaatccag tttattttgg tggtgggtct gctgcttcaa tcaagcgtac
    22741 acggactcgt acgcgcgcta tgatgacagc tatttcagat aagattcgga gtgtagatca
    22801 ggtttttgta gtcggtcaca aaaatttaga catggatgct ttgggctctg ctgtaggtat
    22861 gcagttgttc gccagcaatg tgattgaaaa tagctatgct ctttatgatg aagaacaaat
    22921 gtctccagat attgaacgag ctgtttcatt catagaaaaa gaaggagtta cgaagttgtt
    22981 gtctgttaag gatgcaatgg ggatggtgac caatcgttct ttgttgattc ttgtagacca
    23041 ttcaaagaca gccttaacat tatcaaaaga attttatgat ttatttaccc aaaccattgt
    23101 tattgaccac catagaaggg atcaggattt tccagataat gcggttatta cttatatcga
    23161 aagtggtgca agtagtgcca gtgagttggt aacggaattg attcagttcc agaattctaa
    23221 gaaaaatcgt ttgagtcgta tgcaagcaag tgtcttgatg gctggtatga tgttggatac
    23281 taaaaatttc acctcgcgag taactagtcg gacatttgat gttgctagct atctcagaac
    23341 gcgcggaagt gatagtattg ctatccagga aatcgctgcg acagattttg aagaatatcg
    23401 tgaggtcaat gaacttattt tacaggggcg taaattaggt tcagatgtac taatagcaga
    23461 ggctaaggac acgaaatgct atgatacagt tgttattagt aaggcagcag atgccatgtt
    23521 agccatgtca ggtattgaag cgagttttgt tcttgcgaag aatacacaag gatttatctc
    23581 tatctcagct cgaagtcgta gtaaactgaa tgtacaacgg attatggaag agttaggcgg
    23641 tggaggccac tttaatttgg cagcagctca aattaaagat gtaaccttgt cagaagcagg
    23701 tgaaaaactg acagaaattg tattaaatga aataaaggaa aaggagaaag aagaatgaaa
    23761 gtaatctttt tagcagatgt taaaggaaaa ggtaaaaaag gcgaaattaa ggaagtacca
    23821 acagggtatg cgcaaaactt tcttatcaaa aagaatctag ccaaagaagc gactgctcaa
    23881 gctgtaggtg aacttcgtgg taaacaaaaa tcggaagaaa aagctcacgc tgagatgatt
    23941 gcagaaggga aagcaattaa agcacaactt gaagcagaag aaactgttgt agaatttgtt
    24001 gaaaaagttg gtccagatgg tcgtaccttt ggttctatta ccaataagaa gattgcagaa
    24061 gaattacaaa agcaatttgg aattaagatt gataaacgtc atattcaagt acaagctccg
    24121 attcgagcgg ttggtttgat tgatgtgcca gtgaaaatct atcaagatat cacaagtgta
    24181 atcaatcttc gtgtgaaaga aggataagtt tacaccttct tgacaagatt gtaaaaggaa
    24241 gggaagtctg atggcagaag tagaagagtt acgagtacaa cctcaagata tcttagctga
    24301 gcaatccgtt ttaggggcta tctttattga tgagagtaaa cttgtttttg tgcgagaata
    24361 cattgagtct cgggactttt ttaagtatgc ccatcgtttg attttccaag ccatggtcga
    24421 tttatccgat cgtggtgatg ccatagatgc aacaacggtt cgtactatcc ttgataatca
    24481 aggtgattta cagaatattg gtggcttgtc ttacttggtt gagattgtca attctgtgcc
    24541 aacttctgct aatgcggagt attatgctaa gattgttgca gaaaaagcaa tgctacgtcg
    24601 tttaattgcc aagttgacag agtctgtcaa ccaagcttac gaagcgtcac aaccagctga
    24661 tgaaattatt gctcaggcag aaaaagggtt gattgatgtc agtgaaaatg caaatcgaag
    24721 cgggtttaag aacattcgag atgtgttgaa tctcaacttt ggaaatctgg aagctcgctc
    24781 gcaacaaacg accgatatta caggtattgc gacaggttat cgtgatttgg atcatatgac
    24841 aacaggactt catgaggagg agttgattat cttagcagct cgtccagcag ttggtaagac
    24901 agcatttgcc ttgaatatcg ctcagaacat tgggactaag ttggacaaaa cggttgctat
    24961 tttttcactc gaaatgggtg cggaaagctt ggtagatcgt atgttagctg cagaaggctt
    25021 ggtggagtca cattctatcc gtacagggca attgacagat gaggagtggc aaaaatatac
    25081 tattgctcag ggtaatctag ctaacgccag tatctatatc gatgatacgc caggtattcg
    25141 gattacagag attcgttctc gttcccgtaa attggctcaa gaaactggaa atcttggttt
    25201 gattttgata gactatttgc aacttatcac gggaactggt cgagaaaatc gtcaacaaga
    25261 agtttctgaa atttctcgtc agttgaaaat actagccaag gaattgaagg ttccagtaat
    25321 cgctctgagt cagctttctc gtggtgtaga acaacgtcag gacaagagac cagtcttgtc
    25381 tgatattcgt gaatctgggt ctattgagca ggacgctgat atcgtagctt ttctctatcg
    25441 cgatgactac tatgaacgtg gtggtgaaga agaggagggt atcccaaata ataaggtgga
    25501 agttattatc gagaaaaacc gtagtggagc tcgtggaaca gtggaattga ttttccaaaa
    25561 agaatacaat aaattttcaa gtatctcaaa gagggaggca taagatgtca gatgcattta
    25621 cagatgtagc caagatgaaa aaaatcaaag aagaaatcaa ggcacatgag ggacaagtcg
    25681 tagaaatgac tttggagaat ggtcgtaagc gccaaaaaaa tagattgggt aagctaattg
    25741 aagtttatcc atctctattt attgtggagt ttggggatgt ggaaggagat aaacaagtta
    25801 atgtttacgt tgaatccttt acttactcag atattcttac agaaaagaat ttgattcatt
    25861 atcttgacta aagtgagaaa ttttctcact ttttcttttt tctccgaata atttaggtga
    25921 aggcaatcat cgctttatat tatttttcaa ggaggaagaa tgaaaatttt accgtttata
    25981 gcaagaggaa caagttatta cttgaagatg tcagttaaaa agcttgttcc ttttttagta
    26041 gtaggattga tgctagcagc tggtgatagt gtctatgcct attccagagg aaatggatcg
    26101 attgcgcgtg gggatgatta tcctgcttat tataaaaatg ggagccagga gattgatcag
    26161 tggcgcatgt attctcgtca gtgtacttct tttgtagcct ttcgtttgag taatgtcaat
    26221 ggttttgaaa ttccggcagc ttatggaaat gcgaatgaat ggggacatcg tgctcgtcgg
    26281 gaaggttatc gtgtagacaa tacaccgacg attggttcca ttacttggtc tactgcagga
    26341 acttatggtc atgttgcctg ggtgtcaaat gtaatgggag atcagattga gattgaggaa
    26401 tataactatg gttatacaga atcctataat aaacgagtta taaaagcaaa cacgatgaca
    26461 ggatttattc attttaaaga tttggatggt ggcagtgttg ggaatagtca atcctcaact
    26521 tcaacaggcg gaactcatta ttttaagacc aagtctgcta ttaaaactga acccctagtt
    26581 agtgcaactg tgattgatta ctattatcct ggagagaagg ttcattatga tcagatactt
    26641 gaaaaagacg gctataagtg gttgagttat actgcctata atggaagcta tcgttatgtt
    26701 caattggagg ctgtgaataa aaatcctcta ggtcattctg ttctttcttc aacaggagga
    26761 actcattatt ttaagaccaa gtctgctatc aaaactgaac ccctagttag tgcaactgtg
    26821 attgattact attatcctgg agagaaggtt cattatgatc agatacttga aaaagacggc
    26881 tacaagtggt tgagttatac ggcttataac ggaagtcgtc gctatataca gctagaggga
    26941 gtgacttctt cacaaaatta tcagaatcaa tcaggaaata tctctagcta tggatccaat
    27001 aatagttcaa ctgtcggttg gaagaaaata aatggtagtt ggtatcattt caaatcaaat
    27061 ggttctaaat caacaggatg gctgaaagac ggttctagct ggtattattt gaaattatct
    27121 ggtgaaatgc agacaggatg gttaaaggag aatggctcgt ggtattatct gggtagttca
    27181 ggggcaatga aaacaggctg gtaccaggtc tctggtaagt ggtattattc ttactcttca
    27241 ggcgccttag ctgttaatac gacggtggat ggctacagag taaacagtga tggagaacga
    27301 gtatagaaaa ttggagtagg agaaatttcc tgctcttttc tgtaagcagt ttccttgaca
    27361 tttttcttat tttgcgctat catatataca tataatatat gggagtctgt gtacagtctg
    27421 agaggaagtg ttaaacttcg accgcacctg atctgggtaa tgccagcgga gggaacgata
    27481 cttagtctaa ttttgcacct tttccatgta tggtaaaggt ttttcttttt ttttaaaagg
    27541 aaaacgagaa gaggaggttc ttatgaaagc aagcattgcc ttgcaagttt tacccctagc
    27601 acaggggatt gatcggatag ctgttattga tcaggtcatt gcttatctgc aaactcaaga
    27661 agtgacgatg gtagtgacac catttgaaac ggtcttggaa ggggagtttg atgagcttat
    27721 gcgcattcta aaagaagcgc tggaagtggc agggcaggag gcagacaatg tctttgccaa
    27781 tgtcaaaata aatgtaggag agattttaag tattgatgag aaacttgaaa agtatactga
    27841 gacgacacat tagtctattg ggctttctcg gagtattgtc aatctggcag ttagcaggtt
    27901 ttcttaaact tctccccaag tttatcctgc cgacacctct tgaaattctc cagccctttg
    27961 ttcgtgacag agaatttctc tggcaccata gctgggcgac cttgagagtg gctttactgg
    28021 ggctgatttt gggagttttg attgcctgtc ttatggctgt gctcatggat agtttgactt
    28081 ggctcaatga cctgatttac cctatgatgg tggtcattca gaccattccg accattgcca
    28141 tagctcctat cctggtcttg tggctaggtt atgggatttt gcccaagatt gtcttgatta
    28201 tcttaacgac aacctttccc atcatcgtta gtattttgga cggttttagg cattgtgaca
    28261 aggatatgct gaccttgttt agtctgatgc gggccaagcc ttggcaaatc ctgtggcatt
    28321 ttaaaatccc ggttagcctg ccttactttt atgcaggtct gagggtcagt gtctcctacg
    28381 cctttatcac aactgtggta tctgagtggt tgggaggttt tgaaggtctt ggtgtttata
    28441 tgattcagtc taaaaaactg tttcagtatg ataccatgtt tgccattatt attctggtgt
    28501 cgattatcag tcttttgggt atgaagctgg tcgatatcag tgaaaaatat gtgattaaat
    28561 ggaaacgttc gtagaattag aatgtttctg aaaaagaaaa gaggaaatca aaatgaagaa
    28621 aacatggaaa gtgtttttaa cgcttgtaac agctcttgta gctgttgtgc ttgtggcctg
    28681 tggtcaagga actgcttcta aagacaacaa agaggcagaa cttaagaagg ttgactttat
    28741 cctagactgg acaccaaata ccaaccacac agggctttat gttgccaagg aaaaaggtta
    28801 tttcaaagaa gctggagtgg atgttgattt gaaattgcca ccagaagaaa gttcttctga
    28861 cttggttatc aacggaaagg caccatttgc agtgtatttc caagactaca tggctaagaa
    28921 attggaaaaa ggagcaggaa tcactgccgt tgcagctatt gttgaacaca atacatcagg
    28981 aatcatctct cgtaaatctg ataatgtaag cagtccaaaa gacttggttg gtaagaaata
    29041 tgggacatgg aatgacccaa ctgaacttgc tatgttgaaa accttggtag aatctcaagg
    29101 tggagacttt gagaaggttg aaaaagtacc aaataacgac tcaaactcaa tcacaccgat
    29161 tgccaatggc gtctttgata ctgcttggat ttactacggt tgggatggta tccttgctaa
    29221 atctcaaggt gtagatgcta acttcatgta cttgaaagac tatgtcaagg agtttgacta
    29281 ctattcacca gttatcatcg caaacaacga ctatctgaaa gataacaaag aagaagctcg
    29341 caaagtcatc caagccatca aaaaaggcta ccaatatgcc atggaacatc cagaagaagc
    29401 tgcagatatt ctcatcaaga atgcacctga actcaaggaa aaacgtgact ttgtcatcga
    29461 atctcaaaaa tacttgtcaa aagaatacgc aagcgacaag gaaaaatggg gtcaatttga
    29521 cgcagctcgc tggaatgctt tctataaatg ggataaagaa aatggtatcc ttaaagaaga
    29581 cttgacagac aaaggcttca ccaacgaatt tgtgaaataa tgacagaaat tagactagag
    29641 cacgtcagtt atgcctatgg tcaggagagg attttagagg atatcaacct acaggtgact
    29701 tcaggcgaag tggtttccat cctaggccca agtggtgttg gaaagaccac cctctttaat
    29761 ctaatcgctg ggattttaga agttcagtca gggagaattg tccttgatgg tgaagaaaat
    29821 cccaaggggc gcgtgagtta tatgttgcaa aaggatctgc tcttggagca caagacggtg
    29881 cttggaaata tcattctgcc cctcttgatt caaaaggtgg ataaggcaga aactatttcc
    29941 cgagcggata aaattcttgc gaccttccag ctgacagctg taagagacaa gtatcctcat
    30001 gaacttagcg gtgggatgcg ccagcgtgta gccttactcc ggacctacct ttttgggcat
    30061 aagctctttc tcttagatga ggcctttagc gccttggatg agatgacaaa gatggaactc
    30121 cacgcttggt atcttgagat tcacaagcag ttgcagctaa caaccctgat catcacgcat
    30181 agtattgagg aggccctcaa tctcagcgac cgcatctata tcttgaaaaa tcgccctggg
    30241 cagattgttt cagaaattaa actagattgg tctgaagatg aggacaagga agtccaaaag
    30301 attgcctaca aacgtcaaat cttggcagaa ttaggcttag ataagtagaa aaatagggag
    30361 ttggtgaaga ttatccttta ccagcgccct ttttctttta aaaatgagaa aatttcggta
    30421 taatagtcaa acaaggtcaa ggtttaaaga gagaggtggg tttgttatga gatttaaaaa
    30481 tacatcggat catattgagg cctacatcaa ggcgatttta gatcaatctg gtatcgtgga
    30541 gttgcaacgg agtcagttgg cagatacctt tcaggttgtt cctagtcaga ttaactacgt
    30601 gatcaagaca cgctttacgg aaagtagagg ctacttggtt gaaagtaagc gtggtggcgg
    30661 aggctacatt cgtataggac ggattgagtt ttctagtcat catgaaatgc tccgggagct
    30721 gctttattcg attggtgagc gagtcagtca agaaatttat gaggatattc tccagctttt
    30781 ggttgagcag gaattgatga ccaagcagga gatgaatttg ctagtatcag tagctttgga
    30841 tcgcgtttta ggagaagaag ctccagttgt tcgagcaaac atgctacgtc aggtcataca
    30901 agaggtagat agaaaaggga agtaagatga actattcaaa agcattgaat gaatgtatcg
    30961 aaagtgccta catggttgct ggacattttg gagctcgtta tctagagtcg tggcacttgt
    31021 tgattgccat gtctaatcac agttatagtg tagcaggggc aactttaaat gattatccgt
    31081 atgagatgga ccgtttagaa gaggtggctt tggaactgac tgaaacggac tatagccagg
    31141 atgaaacctt tacggaattg ccgttctctc gtcgtttgca ggttcttttt gacgaagcag
    31201 agtatgtagc gtcagtggtc catgctaagg tgctagggac agagcacgtc ctctatgcga
    31261 ttttgcatga tggcaatgcc ttggcgactc gtatcttgga gagggctggt ttttcttatg
    31321 aagacaagaa agatcaggtc aagattgctg ctcttcgtcg aaatttagaa gaacgggcag
    31381 gctggactcg tgaagatctc aaggctttac gccaacgcca tcgtacagta gctgacaagc
    31441 aaaattctat ggccaatatg atgggcatgc cgcagactcc tagtggtggt ctcgaggact
    31501 atacgcatga tttgacagag caagcgcgtt ctggcaagtt agaaccagtc atcggtcggg
    31561 acaaggaaat ctcacgtatg attcaaatct tgagccggaa gactaagaac aaccctgtct
    31621 tggttgggga tgctggtgtc gggaaaacag ctctggcgct tggtcttgct cagcgtattg
    31681 ctagtggtga cgtgtctgcg gaaatggcta agatgcgcgt gttagaactt gatttgatga
    31741 atgtcgttgc agggacacgc ttccgtggtg actttgaaga acgcatgaat aatatcatca
    31801 aggatattga agaagatggc caagtcatcc tctttatcga tgaactccac accatcatgg
    31861 gttctggtag cgggattgat tcgactctgg atgcggccaa tatcttgaaa ccagccttgg
    31921 cgcgtggaac tttgagaacg gttggtgcca ccactcagga agaatatcaa aaacatatcg
    31981 aaaaagatgc ggctctttct cgtcgtttcg ctaaagtgac gattgaagaa ccaagtgtgg
    32041 cagatagtat gactatttta caaggtttga aggcgactta tgagaaacat caccgtgtac
    32101 aaatcacaga tgaagcggtt gaaacagcgg ttaagatggc tcatcgttat ttaaccagtc
    32161 gtcacttgcc agactctgct atcgacctct tggacgaagc agcagcaaca gtgcaaaata
    32221 aggcaaagta tgtaaaagca gacgattcag atttgagtcc agctgacaag gccctgatgg
    32281 atggcaagtg gaaacaggca gcccagctaa tcgcaaaaga agaggaagta cctgtctaca
    32341 aagacttggt gacagagtct gatattttga ccaccttgag tcgcttgtca ggaatcccag
    32401 ttcaaaaact gactcagact gacgctaaga aatatctaaa tcttgaagca gaactccata
    32461 aacgggttat cggtcaagat caagctgttt caagtattag tcgtgcgatt cgccgtaatc
    32521 agtcaggaat tcgcagtcac aagcgtccga tcggttcctt tatgttccta ggacccacag
    32581 gtgtcggtaa gaccgagttg gccaaggctt tggcagaagt tctctttgat gacgaatcag
    32641 cccttatccg ctttgatatg agtgagtata tggagaaatt cgcagccagc cgtctaaatg
    32701 gagctcctcc aggctatgtg ggttacgaag aaggtgggga gttgacagag aaggttcgca
    32761 ataaacccta ttccgttctc ctctttgatg aggtagagaa ggctcaccca gatatcttta
    32821 atgttctctt gcaggttctg gatgacggtg tcttgacaga tagcaaggga cgcaaggtcg
    32881 atttttcaaa taccattatc attatgacat cgaacctagg tgcgactgcc cttcgtgatg
    32941 ataagactgt tggttttggg gctaaggata ttcgttttga ccaggaaaat atggaaaaac
    33001 gcatgtttga agaactgaaa aaagcttata gaccggaatt catcaaccgt attgatgaga
    33061 aggtggtctt ccatagccta tctagtgacc atatgcagga agtggtgaag attatggtca
    33121 agcctttagt ggcaagtttg gctgaaaaag gcattgactt gaaattacaa gcttcagctc
    33181 tgaaattgtt agcaaatcaa ggatatgacc cagagatggg agctcgccca cttcgcagaa
    33241 ccctgcaaac agaagtggag gacaagttgg cagaacttct tctcaaggga gatttagtgg
    33301 caggcagcac acttaagatt ggtgtcaaag caggccagtt aaaatttgat attgcataaa
    33361 agaataaaag taccagcatc tgaccataag tcacagtgga gtgaaactca atgaaaatca
    33421 aagagcaaac taggcagcta gccgcaggtt gctcaaaaca ctggtttgag gttgcagata
    33481 gagctgacgt ggtttgaaga gattttcgaa gagtataagc tgcaagatga atgattttct
    33541 tgtattgacg ttgttgttga caaaaagtag cggataaatg aaatccattc cattatcata
    33601 gatgataggc tggtaggaaa ttttcaaata gcatacagga aatagatgta tggagttctg
    33661 gtagtagaaa gggagagaga tgaacatttt agttgcagat gacgaggaaa tgattagaga
    33721 aggaattgca gcatttctga cagaagaggg ttatcatgtc attatggcta aggatggaca
    33781 agaggtcttg gaaaaatttc aagatctccc tatccatctc atggtactgg atttaatgat
    33841 gcctaggaag agtggttttg aagtgttaaa agaaatcaat caaaagcacg atattcctgt
    33901 catcgtcttg agtgctctgg gagatgaaac tactcagtca caggtatttg atctctatgc
    33961 tgatgatcat gtgacaaaac ctttttcttt ggtactgctt gtcaagcgta ttaaggcgct
    34021 tatcagacgt tactacgtca tagaggatct ttggcgatat caggatgtaa cagtggattt
    34081 tacctcttac aaagcacatt ataaaaatga agaaattgat ctcaaaccaa aggaattact
    34141 ggtactaaag tgtttgattc agcataaaaa tcaagtttta agtagagagc agatattgga
    34201 agaaatttca aaagatgtag ctgatttacc ttgtgatagg gtcgttgatg tctatattcg
    34261 tactcttcgc aaaaaattag ctttagattg tatcgtgact gtgaaaaatg ttgggtataa
    34321 gattagctta tgataaaaaa tcctaaatta ttaaccaagt cttttttaag aagttttgca
    34381 attctaggtg gtgttggtct agtcattcat atagctattt atttgacctt tcctttttat
    34441 tatattcaac tggaggggga aaagtttaat gagagcgcaa gagtgtttac ggagtattta
    34501 aagactaaga catctgatga aattccaagc ttactccagt cttattcaaa gtccttgacc
    34561 atatctgctc accttaaaag agatattgta gataagcggc tccctcttgt gcatgacttg
    34621 gatattaaag atggaaagct attaaattat atcgtgatgt tagatatgtc tgttagtaca
    34681 gcagatggta aacaggtaac cgtgcaattt gttcacgggg tggatgtcta caaagaagca
    34741 aagaatattt tgcttttgta tctcccatat acatttttgg ttacaattgc tttttccttt
    34801 gttttttctt atttttatac taaacgcttg ctcaatcctc ttttttacat ttcagaagtg
    34861 actagtaaaa tgcaagattt ggatgacaat attcgttttg atgaaagtag gaaagatgaa
    34921 gttggtgaag ttggaaaaca gattaatggt atgtatgagc acttgttgaa ggttattcat
    34981 gagttggaaa gtcgtaatga gcaaattgta aaattgcaaa atcaaaaggt ttcctttgtc
    35041 cgtggagcat cacatgagtt gaaaatccct ttagccagtc ttagaattat cctagagaat
    35101 atgcagcata atattggaga ttacaaagat catccaaaat atattgcaaa gagtataaat
    35161 aagattgacc agatgagcca cttattagaa gaagtactgg agtcttctaa attccaagag
    35221 tggacagagt gtcgtgagac cttgactgtt aagccagttt tagtagatat tttatcacgt
    35281 tatcaagaat tagctcattc aataggtgtt acaattgaaa atcaattgac agatgctacc
    35341 agggtcgtca tgagtcttag ggcattggat aaggttttga caaacctgat tagtaatgca
    35401 attaaatatt cagataaaaa tgggcgcgta atcatatccg agcaagatgg ctatctctct
    35461 atcaaaaata catgtgcgcc tctaagtgac caagaactag aacatttatt tgatatattc
    35521 tatcattctc aaatcgtgac agataaggat gaaagttccg gtttgggtct ttacattgtg
    35581 aataatattt tagaaagcta tcaaatggat tatagttttc tcccttatga acacggtatg
    35641 gaatttaaga ttagcttgta gacagattag ttttttatta aagttcatat agggttaaca
    35701 taagtgtgtt attctttgtg tagataaaag aaaggatact aatatggtat tagcgattat
    35761 tttagtaaca ttctttattc gattgatttt tttaaagcgt tcgatagaga atgagaaacg
    35821 aatccttagc aatggcggga aagaatttgg agttgagaat acaaaacgat taactatggc
    35881 tcatattgtt ttttatctct cttgcttggt tgaggcaatg gtgcacaaga caatttttga
    35941 tggcatgggc atggttggtt tagtcttgct tattttttct atgctgatgt taatgttggt
    36001 gattcacttg ttgggagata tttggacagt gaagcttatg cttgtcaata atcacaaata
    36061 tgtagatcat atcttgttta ggacagtaaa acatcctaat tactttttaa atattcttcc
    36121 tgagttgatt ggcttgacct tgttgagtca tgcttatgtg acttttgttt tagtttttcc
    36181 agtttatgca gttattttgt atcgacgaat agctgaagag gaaaagctat tacatgaagt
    36241 tataatccca aatggaagca taaagagata aatacaaaat tcgatttata tacagttcat
    36301 attgaagtaa tatagtaata gacttcatgc gaaacaaaat atggtacaat agttctatga
    36361 attatgaagc aaggttgaga atatttttgc caaagtaaaa acgtttaaaa tgttttcaac
    36421 aacctatcga aatcatcgta aacgcttcgg attacgaatg aatttgattg ctggcattat
    36481 caatcatgaa ctaggattct agttttgcag gaagtctaat gttaagaaaa atattggaga
    36541 aaataaacat gtttgcatca aaaagcgaaa aaaaagtaca ttattcaatt cgtaaattta
    36601 gtattggagt agctagtgta gctgttgcca gtctttttat gggaagtgtg gttcatgcag
    36661 aaggggttag aagtggggat acccctaagg ttacatctag tggggatgaa gtcgagtcgc
    36721 atctaaaaaa aatattgagt gagatccaaa cacaattaga tagaaaacga catgccaaaa
    36781 ctgtagcgct aattaacaag ttgcaagaca ttaagagaac gtattcgtat aaattaaatg
    36841 ttttagaaga gaagccgaaa gctgagttga cgtcaaaaac aaaagaagag ttaaccgcag
    36901 cttttgagca gtttaaaaaa gatacattac caacagaacc aggaaaaaag gtagcagaag
    36961 ctaagaagaa ggttgaagaa gctaagaaaa aagccaaggc tcaaaaagaa gaagattacc
    37021 gtaactaccc aaccaatact tacaaaacgc ttgaacttga aattgctgag ttcgatgtga
    37081 aagttaaaga agcggagctt gaactagtaa aaaaggaagc tgacgaatct cgaaatgagg
    37141 gcacaattaa ccaagcaaaa gcgaaagttg agagtgaaaa agctgaggct acaaggttaa
    37201 aaaaaatcaa gacagatcgt gaaaaagcag aagaagaagc taaacgaaga gcagatgcta
    37261 aagagcaaga tgaatcaaag aggcgaaaga gtcgggtaaa acgaggagat cttggagagc
    37321 aagcaacacc tgataaaaaa gaaaatgatg cgaagtcttc agattctagc gtaggtgaag
    37381 aaactcttcc aagcccatcc ctgaaaccag gaaaaaaggt agcagaagct gagaagaagg
    37441 ttgaagaagc tgataaaaaa gccaaggctc aaaaagaaga agatcgccgt aactacccaa
    37501 ccaatactta caaaacgctt gaacttgaaa ttgctgagtc cgatgtgaaa gttaaagaag
    37561 cggagcttga actagtaaaa gaggaagcta aggaatctca aaacgaggaa aaaattaagc
    37621 aagcaaaagc gaaagttgag agtaaaaaag ctgaggctac aaggttagaa aaaatcaaga
    37681 cagatcgtaa aaaagcagaa gaagaagcta aacgaaaagc agcagaagaa gataaagtta
    37741 aagaaaaacc agctgaacaa ccacaaccag cgccggctcc tcaaccagaa aaaccaactg
    37801 aagagcctga gaatccagct ccagctccaa aaccagagaa gccagctgaa caaccaaaag
    37861 cagaaaaacc agctgatcaa caagctgaag aagactatgc tcgtagatca gaagaagaat
    37921 ataatcgctt gactcaacag caaccgccaa aaattgaaaa accagctcca gcaccacaac
    37981 cagagcaacc agctccagca ccaaaaacag gctggaaaca agaaaacggt atgtggtact
    38041 tctacaatac tgatggttca atggcaacag gatggctcca aaacaatggt tcatggtact
    38101 acctcaacag caatggcgct atggcgacag gatggctcca aaacaatggt tcatggtact
    38161 atctaaacgc taatggttca atggcaacag gatggctcca aaacaatggt tcatggtact
    38221 acctcaacgc taatggttca atggcgacag gatggctcca atacaatggt tcatggtact
    38281 acctcaacgc taatggtgat atggcgacag gatggttcca atacaatggt tcatggtact
    38341 acctaaacgc taatggtgat atggcgacag gatggctcca atacaatggt tcatggtact
    38401 acctcaacag caatggtgct atggtaacag gatggctcca aaacaatggc tcatggtact
    38461 acctcaacgc taacggttca atggcaacag attgggtgaa agatggagat acctggtact
    38521 atcttgaagc atcaggtgct atgaaagcaa gccaatggtt caaagtatca gataaatggt
    38581 actatgtcaa tggctcaggt gcccttgcag tcaacacaac tgtagatagc tatagagtca
    38641 atgccaatgg tgaatgggta aactaaacct aatataacta gttaatactg acttcctgta
    38701 agaactcttt aaagtattcc ctacaaatac catatccttt cagtagataa tatacccttg
    38761 taggaagttt agattaaaaa ataactctgt aatctctagc cggatttata gcgctagaga
    38821 ctacggagtt tttttgatga ggaaagaatg gcggcactca agagactctt taagagagtt
    38881 acgggtttta aactattaag ccttctccaa ttgcaagaga gcttcaatct ctgccagggt
    38941 gctagcttgc gaaatggctc cacggagttt ggcagcgcca gatgttccac ggaggtagtg
    39001 aggagcgagg ccacggaatt cacgaactgc gacgttttct cctttgaggt taatcaatcg
    39061 tttcaagtgt tcgtaggcga tcttcatctt gtcttcaaag gtcaaatcag gtaggatttc
    39121 tcctgtttca aagtaatggt tgatttggtt gaagaggtaa ggatttccca tggcagctcg
    39181 gccaatcatg actgcgtcag caccaacttc ttcgatgcgt tgcttggctt cttggacagt
    39241 acggatatca ccgttggcga tgaatggaat cttggttaga gcttgggcaa ccttgtaaag
    39301 ggtctcaagg tctgcgtggc cagtatacat ttgttcacgg gtacggccat gcatggcgag
    39361 ggcagaaaca cctgcagcct cagcagcgag ggcattttct actgccagag atgggtccgc
    39421 ccagccggta cgcattttga cagtaagtgg gatatcaagg acagactgga ccttgttgat
    39481 gatagagtag atcttgtcag gatccttgag ccacatagca ccagcttcgt tcttcacgat
    39541 tttgttgaca gggcagccca tgttgatatc gacgatatcg gtcttagtgt tttcttggat
    39601 aaattctgct gcgcgtgcta ggctgtcttc atcgctacca aaaagttgga tagagacagg
    39661 gttttcgccc tcatcgatat gaagcatgtg cagggttttt tcgttgttgt attggattcc
    39721 cttgtcagag accatttcca ttacaacgag tccagctccg agctcttttg cgatggtacg
    39781 aaaggctgag ttggtcacgc cagccatagg cgctaaaacg gtacgattgg gaatctcaac
    39841 attgccaatc ataaaaggtg tattaagatt tgtcacgaat gagttcctcc aggtcctttt
    39901 catcaaagtt gtaagtagtt tggcagaatt gacaagtgat ttctaccccg tggtcttcct
    39961 ctttcatttc ctgtaagtct gagcttggaa ggctggcaag agcgttcata aagcgttcat
    40021 ggctacagtc acattggaaa cggatttctt cttcagaaag acgcttgtag gcttcgtccc
    40081 cgtagatagc cttgaggagg gcttcgatat ggtcgtcgct ttcgagaaga gtagagatag
    40141 ctggcatttc ttggatgcgt ttttcaaagc gagcaatctc ttctttcttg gctcctggca
    40201 agacttgaac taggaaacca cctgcaatct tgaccttgtc ttcctcgtcc aaaaggacat
    40261 tgaggccgac cgctgaaggc gtttgttggc tttcagtaag gtaaaaggca aggtcttcac
    40321 cgatttctcc agagatgagg ggagttatag agttgtaagg atttccagta ccgtagtctg
    40381 tgataacgag gaattgacca tttccaacaa aaggtccgac taggacttca ccagtcgcag
    40441 tctttttgat gtcaacacca ggattttgaa cgtagccttt gacgttcccc ttggtatcag
    40501 cgacggtgat aatagcacct agagagctag atcccaacac cttaactgta agtttggtat
    40561 ttcctttttc attggctgcg agaatctggc tagcgataag agttcgacca agcgctacag
    40621 ttgagctagc ttgggtttga tgtttttctt gagcagtgcg gacggtttca gtgctatcaa
    40681 ggacaaaagc acgaaaggct ccgctttctg atatagtttt aataatttta tccatagcta
    40741 ctattttagc ataaaaatgc ccaaaggggg agccgtgtgt ttactgattt tcaggataat
    40801 ggaccaggaa atcagcatga aaataaaaag agaaacagat tatttcagca tttgtaagat
    40861 ttatgctatg cttaaggtag aaaatgaaag ggataacaaa tgtatttagg agatttgatg
    40921 gagaaagccg agtgtggtca attttcaatc ctttcctttc tattacaaga gtctcagacg
    40981 accgtcaagg ctgtaatgga agaaacagga ttttcaaaag caaccctaac caaatatgtc
    41041 accctgctca atgacaaggc tttggatagt ggcttagaac tgactattca ctcagaagat
    41101 gaaaatctgc gtctgtctat cggtgcagct accaagggga gagatattcg gagcttgttt
    41161 ttggagagtg ctgttaaata ccagattttg gtttatcttc tctaccacca acagttttta
    41221 gcccatcagc tggctcaaga attggtgatt agcgaggcta cgcttggtcg tcacttggct
    41281 ggtttaaatc agattttgtc agaatttgat ttatccatcc aaaatggacg ttggcgaggt
    41341 ccagagcatc agattcgcta tttctatttc tgtcttttcc gaaaggtctg gtcgagtcag
    41401 gaatgggaag gtcacatgca gaaaccagag agaaaacagg agattgccaa tttagaggaa
    41461 atctgcggtg caagtttgtc tgtggggcag aaattggact tggttctctg ggctcacatc
    41521 agtcaacaac gtcttcgggt caatgcttgt cagtttcaag tcatagaaga gaaaatgcga
    41581 gggtattttg acaatatctt ttatcttcgt ttgctgagaa aggttccgtc cttttttgct
    41641 gggcaacata ttccactagg agttgaggat ggtgagatga tgatattctt ctcttttctc
    41701 ctatctcatc gcattcttcc tcttcatact atggagtata ttcttggttt tggagggcag
    41761 ttggcagatt tactgacgca attgattcaa gaaatgaaga aggaggaact attgggggat
    41821 tatacagagg accatgtcac ctatgaactc agtcagcttt gtgctcaagt ctatctctat
    41881 aagggctata ttttacagga tcgttacaag taccagttag agaatcgtca tccatattta
    41941 ctgatggaac atgattttaa agagacagca gaggagattt ttcatgctct acctgctttt
    42001 caacagggga cagatttaga taagaagatt ctctgggaat ggctccagtt aatcgaatat
    42061 atggctgaaa acggtggcca gcatatgcgg attggtctgg atttgacatc tggttttctt
    42121 gtcttttcaa ggatggcagc cattttgaaa cggtatttag aatacaatcg ttttattacc
    42181 attgaagctt atgaccctag tcggcattat gatttgctgg ttaccaataa cccgattcat
    42241 aagaaggaac agaccccagt ctattattta aaaaatgact tggatatgga ggatttggca
    42301 gggattcgtc agttattatt cacttaaaag gcttggttgt tccaggtctt ttttgtgaaa
    42361 ttcacacaat ctcctcacgt ttttttaaaa attaaaaaaa gttgataaac aagaaagcgc
    42421 tttattttgt atactagtaa gtgtaaagag gaaacacctc aagatcttta tcaggaggac
    42481 agtacatgtc acaagaaaaa tacatcatgg ccattgacca gggaactaca agttctcgtg
    42541 ccatcatttt caacaaaaaa ggggaaaagg ttagctcgag tcaaaaagag tttacccaga
    42601 ttttccctca ggcaggttgg gttgagcaca atgccaatga aatttggaac tctgttcagt
    42661 cagttattgc gggtgctttc attgaaagtg gtgtcaagcc aaatcaaatc gaggcaatcg
    42721 ggattaccaa ccaacgtgaa acaacggttg tctgggataa gaaaacagga cttcctatct
    42781 acaatgctat cgtttggcag tcacgccaga cagcaccttt ggctgagcaa ctaaaaagcc
    42841 aaggttatgt ggaaaaattc catgaaaaga ctggtttgat tattgatgct tacttctctg
    42901 ctaccaaggt tcgttggatt ttggatcatg tagaaggtgc tcaagagcga gcagaaaaag
    42961 gggaattgct ctttggtact atcgatactt ggttggtttg gaaattgact gacggtgcgg
    43021 ctcacgtgac tgactactca aatgcagctc gtaccatgct ttataacatt aaagaactca
    43081 aatgggatga tgagattttg gaaatcctta acattccgaa ggctatactt ccagaagttc
    43141 gttctaactc cgaaatctac ggcaagacag ctccattcca tttctacggt ggagaggtgc
    43201 caatctcagg tatggctggg gaccaacaag cagccctctt tggacagttg gcttttgagc
    43261 caggtatggt taagaatact tatggaacag gctctttcat catcatgaat actggggaag
    43321 agatgcagtt gtctgaaaac aacctcttga caaccattgg ttacggaatc aacggtaagg
    43381 tttattatgc cttggaaggt tctatcttca tcgcaggaag tgctattcag tggcttcgtg
    43441 acggtcttcg catggttgaa aattcaccag aatctgaaaa atacgctcgt gattctcaca
    43501 acaacgatga agtttatgtc gttccagcct ttacaggtct aggcgctcca tactggaacc
    43561 aaaatgctcg tggttccgtc tttggtttga ctcgtggaac aagcaaagaa gactttatca
    43621 aggcgacttt gcaatctatt gcttatcaag tgcgtgacat catcgacacc atgcaagtgg
    43681 atactcagac cgccattcaa gtactgaagg tggatggtgg tgcagccatg aacaacttcc
    43741 tcatgcagtt ccaggcggat attttaggca ttgatattgc acgtgctaaa aacttggaaa
    43801 caacagctct aggagcggcc ttcctagcag gtttgtcagt agggtactgg aaagacttgg
    43861 acgagttgaa actcttgaac gagacaggag aactctttga gccatctatg aacgaatctc
    43921 gcaaggaaca actctataag ggctggaaga aggctgtgaa agcaactcaa gtctttgcgg
    43981 aaatcgatga ctaatactca atgaaaatca aagagcaaac taggaagcta gccgcaagct
    44041 gtacttgagt acggtaaggc gacgctgacg tggtttgaag agattttcga agagtataat
    44101 actggcagaa taaagcgatt tagttagaaa gtgtgtaaat atggaatttt caaagaaaac
    44161 acgtgaattg tcaattaaaa aaatgcagga acgcaccctg gacctcttga ttatcggtgg
    44221 aggaatcaca ggagctggtg tagccttgca ggcggcagct agcggtcttg agactggttt
    44281 gattgaaatg caagactttg cagaaggaac atctagtcgt tcaacaaaat tggttcacgg
    44341 aggacttcgt tacctcaaac aatttgacgt agaagtggtc tcagatacgg tttctgaacg
    44401 tgcagtggtt caacaaatcg ctccacacat tccaaaacca gacccaatgc tcttaccagt
    44461 ttacgatgaa gatggagcaa cctttagcct cttccgtctt aaagtagcca tggacttgta
    44521 cgatctcttg gcaggtgtta gcaacacacc aactgcgaac aaggttttga gcaagaaaga
    44581 agtcttggaa cgccagccaa acttgaagaa ggaaggcttg gtaggaggtg gagtgtatct
    44641 tgacttccgt aacaacgatg cgcgtctcgt gattgaaaac atcaaacgtg ccaaccaaga
    44701 cggtgccctc attgccaacc acgtgaaggc agaaggcttc ctctttgacg aaagtggcaa
    44761 gattacaggt gttgtagctc gtaatctttt aacagaccaa gtatttgaaa tcaaggcccg
    44821 tctggttatt aatacaacag gtccttggag tgataaagta cgtaatttgt ctaataaggg
    44881 aacgcaattc tcacaaatgc gcccaactaa gggagttcac ttggtagtgg attcaagcaa
    44941 aattaaggtt tcacagccag tttactttga cacaggtttg ggtgacggtc gtatggtctt
    45001 tgttctccca cgtgaaaaca agacttactt tggtacaact gatacagact acacaggtga
    45061 tttggagcat ccaaaagtaa ctcaagaaga tgtagattat ctacttggca ttgtcaacaa
    45121 ccgctttcca gaatccaaca tcaccattga tgatatcgaa agcagctggg caggtcttcg
    45181 tccattgatt gcagggaaca gtgcctctga ctataatggt ggaaataacg gtaccatcag
    45241 tgatgaaagc tttgacaact tgattgcgac tgttgaatct tatctctcca aagaaaaaac
    45301 acgtgaagat gttgagtctg ctgtcagcaa gcttgaaagt agcacatctg agaaatattt
    45361 ggatccatct gcagtttcac gtggttcgag cttggaccga gatgataatg gcctcttgac
    45421 ccttgctggt ggtaaaatca cagactaccg taagatggct gaaggtgcta tggagcgcgt
    45481 ggttgacatc ctcaaagcag aatttgaccg tagctttaaa ttgatcaatt ctaaaactta
    45541 ccctgtttca ggtggagaat tgaacccagc aaatgtggat tcagaaatcg aagcctttgc
    45601 gcaacttgga gtttcacgtg gtttggatag caaggaagct cattacctag caaatcttta
    45661 tggttcaaat gcaccgaagg tctttgcact tgctcacagc ttggaacaag cgccaggtct
    45721 tagcttggca gacaccttgt cccttcacta tgcaatgcgc aatgagttga ctcttagccc
    45781 agttgacttc cttcttcgtc gtaccaatca catgctcttt atgcgtgata gcttggatag
    45841 tatcgttgag ccaattttgg atgaaatggg acgattctat gactggacag aagaagaaaa
    45901 agcaacttac cgtgctgatg tcgaagcagc tctcgctaac aacgatttag cagaattaaa
    45961 aaattaagaa aaaataaaag aggtggaggg cagcattcct tgtcgcccgt cccttctttt
    46021 taatggagac agaaagatga tgaatgaatt atttggagaa tttctaggga ctttaatcct
    46081 gattcttcta ggaaatggtg ttgttgcagg tgtggttctt cctaaaacca agagcaatag
    46141 ctcaggttgg attgtgatta ctatgggttg ggggattgca gttgcggttg cagtctttgt
    46201 atctggcaag ctcagtccag ctcatttaaa cccagctgtg accatcggtg tggccttaaa
    46261 aggtggtttg ccttgggctt ccgttttgcc ttatatctta gcccagttcg caggggccat
    46321 gctgggtcag attttggttt ggttgcaatt caaacctcac tatgaggcag aagaaaatgc
    46381 aggcaatatc ctggcaacct tcagtactgg accagccatc aaggatactg tatcaaactt
    46441 gattagcgaa atccttggaa cttttgtttt ggtgttgaca atctttgctt tgggtcttta
    46501 cgactttcag gcaggtatcg gaacctttgc agtgggaact ttgattgtcg gtatcggtct
    46561 atcactaggt gggacaacag gttatgcctt gaacccagct cgtgaccttg gacctcgtat
    46621 catgcacagc atcttgccaa ttccaaacaa gggagacgga gactggtctt acgcttggat
    46681 tcctgttgta ggccctgtta tcggagcagc cttggcagtg cttgtattct cacttttcta
    46741 gtttatactc ttcgaaaatc aaattcaaac cacgtcagcg tcgccttacc gtactcaagt
    46801 acagcttgcg gctagcttcc tagtttgctc tttgattttc attgagtatt agaaaacaat
    46861 tatgttgata gagcttgggc aagagcccaa tttcagcaaa aaatgaagta aatcttctca
    46921 taataaaacg catcatatca agcacgaaaa ttccacgagg tcaactacag tcagaaagct
    46981 gaacaacaag ccaaaacgcc caaaaaaggc ggcaaaaagc aagcacctgc aagcaacgtg
    47041 ccgaaatggt caaatcctga ttatgtcaac gaattagacc caaaaatcgt tgatatgcta
    47101 gtagaatttc acaagtcaca aggcactttg gaaactcccg aggcgcaagc agaaatcgcc
    47161 caaaaacgtg aagaaatcga gcaaaggaga gctgagcttg aggataaaaa acaagagctt
    47221 ttgaaccgct tgaacaaata gagtttcgca agtattatgc ttacaaatta cttgagcaat
    47281 taactaaaat ataaaccctg cctagatata aaggcagggt ttatatttta gaaattcacg
    47341 taggttgtta cggtttttac atacccagta tagtttgagt ttctatagta ttcagtgata
    47401 aacttccatt ttctttgagc aacatggata taagtacttg ttatgtagta tggatatggg
    47461 ctttgtgaat ccaagtaaga ctgataagct tgtataccaa aatatgctcc accaattatt
    47521 gcaccccatg gaccccccaa taaagcacct atcctaccaa tcatataact gattccagca
    47581 ccagtcatga agttagcgaa tgtgttagct tgtttattcc catgtattgt gttgacgtaa
    47641 ttccaaacat taggatcgta tgatctaaaa gatatattta ggtcgatttc attcttttga
    47701 taagccatat aaaatgcccc attgatatag acgccgtcag cacgtcgttc aatagtgtct
    47761 acacttccat ctggattgac aacctcaaga acttcatcgc ttaaaatatt tacttgcgta
    47821 tctccgaacc gcactgatga gccattctca aactgagcct caccagatac aactttagag
    47881 tttgccgata agctatcatc agcaaaaaca acaagcgacg gggaaatgct agacatacag
    47941 aaaacagaca taactagcaa acacatgcat ttaaacatct tagacataac ggaaactctt
    48001 ttgtattttt gatttttttc aacttttatt atacaataaa accaaataaa aagaaagcgg
    48061 taacaatatg cttaatgcga aaatttttta tatattttta tgtttgatcg ttatcgaaac
    48121 tacaggcttg ttgttgttga aaagaggtct cgaaatgggt tatttagaca cagaagctat
    48181 tatcctcgca gttttttcat ttgcttttta caacctatgt tcattcgctt gggtctgctc
    48241 tacaataaaa aacaataaaa aataaataga cgtattttca aaaaaaaaaa aaagcatatt
    48301 tatattagta aaacgacgat ttaaatcgtc gttttttttg tagtacgacg ggcatgtcgt
    48361 atatctgagg tgtaagtcct cggtgggcac ctgctaccgg tgaacccaat agcgattccc
    48421 aagcctgact atcgtgaggt agcggggaga ggaagagata gcgaaatcgt ggctctacga
    48481 acaggaacgt gatagcaagg cgtatatagc ggataaggag gcttcaaact ctaaagtcca
    48541 aaaaggtagt cgtaacctat atgtgtaaat cacgagagta attgaattcg gactaaggtt
    48601 tgtgtgaaaa agataaatct ttctagagtc taaagactct gcgtcagatt tcctattttt
    48661 actgtaacct tttaacgtcc tcatatcttg tataaacgag gaaagatgta cgacttatcc
    48721 cgtgaggttt catgagcgct gaaagcgtag taacaacgaa tcatgagaag tcagccgagc
    48781 ccatagtagt gaggaaactt ccgtaatgga agtggagcga aggggtgaac aactaatcga
    48841 agtaatccta cttcacttgt gtctgtaaaa cgaacggtct gatagaactg gactctgtca
    48901 cgtattgact agatgaaggt tcaccaatat aagatgtccc tcaggcacca aaacaagaaa
    48961 ggaatacgca catgtcaaaa ttgctagata agatattatc acgcgaaaat atgctggaag
    49021 cctacaatca agtaaaatcc aataaaggct cagctgggat tgatggaatg actatcgaag
    49081 agatggataa ttatctcaga caaaactggc gcttgactaa ggaactgata aaacagagaa
    49141 aatataagcc tcaaccagtt cttaaagttg agatacctaa accagacggc ggcatccgtc
    49201 aactaggaat tccaacagtt atggatagaa tgattcaaca ggccattgtc caagtcatga
    49261 gccccatttg tgaaccccat ttctcagata cgagttatgg tttcagacca aataggtcat
    49321 gtgaaaaagc tatcatgaag ctcttagaat acttaaatga cggctatgag tggatagtgg
    49381 atatagacct agagaaattt ttcgatacag ttcctcaaga tagattgatg tccttagtac
    49441 ataacattat cgaagacgga gatacggaat ccttgattcg taagtatctt cattcaggtg
    49501 ttatcattaa tggtcaacgt tataaaacac tagttggtac accacaggga ggaaatttat
    49561 ctcctctctt atccaatatc atgcttaatg aattggacaa ggaattagaa aagaggggac
    49621 ttcgatttgt gcgctacgca gatgattgtg tgattacggt cggaagcgag gcagcctcta
    49681 agcgtgtgat gtattcagtc agtcgtttta ttgagaaacg gctaggtttg aaagtaaaca
    49741 tgaccaagac taagattacc agaccaagag agttgaaata tctaggtttt gggttctgga
    49801 aatcatcaga tggttggaaa agccgtcccc atcaagatag tgttcggaga tttaagttta
    49861 aattgaagaa actaacacag aggaaatgga gtatagacct aacaagacgt attgagcaac
    49921 tgaatttgtc tattcgagga tggataaact atttctcatt gggaaatatg aaaagtatag
    49981 tcgccagcat agatgagcgc ttgcctactc gcctacgagt gattatctgg aagcaatgga
    50041 agaagaaatc gagacgatta tggggattgc ttaagttagg agttcctaaa tggatagcag
    50101 ataaggtatc tggctggggc gaccattatc aattagtagc tcagaagtcg gtacttaaac
    50161 gtgctatatc aaaaccagtc ctggaaaaac gtggactggt ttcgtgtttg gattattacc
    50221 ttgaacgaca tgcgttaaaa gttagttgaa ccgccgtatg ccgaacggca cgtacggtgg
    50281 tgtgagaggg gctagagatt atcctctact cgattaactc ccctgaaatt tattttaatt
    50341 atgcaaattt cacgtatttt tgatgctgag acgacgatcc tgggaacttt tcagatattt
    50401 ttttgactat ctaaatctat cattagaaaa gcttagagcg ccaaaggatt tgagcgtttt
    50461 tctgattttt aagacttttt cccagtctct ttttcgattg aagatgtaat tattctacta
    50521 actaactaac ttcttagtac tagccaacaa cgataatcat aattcctcct aaaattagga
    50581 ataataaagg caatagtttt tgttttttca tgtaaaaaac ctcacttttg ttttctgcta
    50641 ttttatgcta aaatattaaa aatcaaattt aattccaaag tttgtaacta aagggggagc
    50701 gctacatgtc taattcattt gtcaagttgt tagtctctca attatttgca aatttagcag
    50761 atattttctt tagagtaaca atcattgcta acatatacat tatttcaaaa tcagtaattg
    50821 ccacatcact agttcctatc ttaataggaa tatcctcttt tgttgcgagt cttttagttc
    50881 cgttggttac taaaaggtta gcgctaaata gggttttatc tttatctcaa tttggaaaga
    50941 ctatattatt ggcgatactg gtaggaatgt ttaccgtaat gcaatccgta gcgcctttgg
    51001 tgacctatct atttgttgtt gcaatttcca tactagatgg ttttgcagca cccgtttcct
    51061 atgctattgt gccacgctat gcgaccgatt tgggtaaggc taattcagcc ttatcaatga
    51121 ctggtgaagc tgctcaattg ataggttggg gattaggtgg actcttgttt gcaacaattg
    51181 gtctgttacc taccacgttt atcattttag tcttgtatat catttctagc tttctgatgt
    51241 tatttcttcc taacgctgaa gtggaggtgt tagagtcaga aactaatctt gaaattttgc
    51301 tcaaaggttg gaagttagtt gctagaaatc ctagattaag actttttgta tcagcaaatt
    51361 tattggaaat tttttcaaat acgatttggg tttcttccat tatacttgtt tttgtaacgg
    51421 agttattaaa taaaacggaa agttactggg gatattctaa tacagcatac tctattggta
    51481 ttataattag tggcttaatt gcttttaggc tatctgaaaa gttccttgct gctaaatggg
    51541 aaagtattct ttttcctctt gtagctatgg caatagtgac actgactatt ctatattttc
    51601 caaacgcaca gatgttttta ttattttcag ctttagttgg tatgttatcg caactaaaag
    51661 aagttcctga aagtgtattt cttcaggaaa cagtagagga aaatcattta gttaatgtct
    51721 attccgttct tgaagtgatt tctacattag cattttcagt atttgttttg ctaatgagct
    51781 atattactga ttttggctat cagccatttg tctgatgata gaagctattt taatttatat
    51841 cagacgagat tattttaaat gagagagtgg ttaaaaagtc tttaaaaatc agaaaagcgc
    51901 atagtatcag gtgttgaaaa aacttgatat tgtgtgtttt attatgggaa gatttacttc
    51961 attgtctcct gaaatggagt tttgaagcag aatcactcta tttgaaaata tacatagaaa
    52021 aaccgcataa tccttaaaat aagctgaaat ctattggaaa catacggtaa acaattgaaa
    52081 agatactata taaagtggta caatggtaga agaataagct agtaagaatc actcttattt
    52141 tagcgaaaaa ttacagaaat gaatggtttt tcttgatgaa acagagaaaa gaattgtacc
    52201 tctttcttgg taggacagcc ttgtattttc ttatctttct agggctgctt tacttcttta
    52261 gctatcttgg tcagggtcaa ggaagcttta tctataatga attttaactt gaaggagaat
    52321 ccctattgtg tcaaataaac caatagcaga tatgattgaa accattgagc attttgctca
    52381 gacacagcct agctatcctg tctataatgt tttggggcag gaacacactt atggcgattt
    52441 aaaggctgat tcggatagtt tggctgcagt cattgaccaa ctaggcttgc ctgagaagtc
    52501 tcctgtggtt gtttttggtg gccaagaata tgaaatgttg gcaacctttg tagcgctgac
    52561 taagtcaggt catgcctaca ttccaattga tagccattcg gccttggagc gagtttcagc
    52621 tattttagaa gtagcagagc caagcttgat tattgccatt tcagcctttc ccttggagca
    52681 ggtttctaca ccaatgataa atctagctca ggttcaagaa gcctttgccc aagggaacaa
    52741 ctatgaaatc acgcatccag tcaagggaga tgataattac tacattatct ttacttctgg
    52801 tacgactggt aagcctaagg gagtgcagat ttcacatgat aatctcctca gctttacaaa
    52861 ctggatgatt acggataagg aatttgcgac accgagtcgt ccgcaaatgc tggcacaacc
    52921 accttattct tttgacttgt ctgtcatgta ttgggcaccg accttggcac ttggtggtac
    52981 gcttttcact cttccttcag tcatcactca ggactttaag caactctttg cggctatctt
    53041 ttcattgcca atcgctatct ggacatcaac accatccttt gcagatatgg ccatgttgtc
    53101 tgaatacttc aacagtgaga aaatgcctgg aatcacgcat ttctactttg atggtgaaga
    53161 attgacggtc aaaacagctc aaaaactgcg cgagcgtttc ccaaatgccc gtatcatcaa
    53221 tgcttacggc ccaacagaag cgacagtagc tctgtcagca gttgccgtga cagacgagat
    53281 gttagcgact ctcaaacgcc taccaatcgg ctataccaag gctgattctc caacctttat
    53341 cattgacgag gaaggaaata aactgccaaa tggcgaacag ggagaaatca ttgtttctgg
    53401 gccagctgtt tcaaaaggtt atatgaacaa tcctgaaaaa acagcagaag ccttctttga
    53461 gtttgaaggt ctgccagcct atcacacagg cgatgtggga accatgacag atgagggctt
    53521 gcttctctac ggcggacgca tggacttcca gattaagttt aacggttacc gcattgagtt
    53581 agaagatgtc tctcaaaacc tcaacaagtc tcgctttatc gaatctgctg tcgcagtacc
    53641 gcgctataac aaggaccaca aggtacaaaa tctattggct tatgtcatct taaaagacgg
    53701 tgttcgtgag cagtttgagc gagatatcga tattaccaag gccatcaagg aagacctgac
    53761 agacatcatg atgtcctata tgatgccatc taaattcctt taccgagaca gtttgccact
    53821 aactccaaat ggaaagattg acatcaaagg attgattaac gaggtgaata agagatgatg
    53881 gagttttttc aacagcttcc tcatttagag ccatatggca atcctcagta ttttgtttat
    53941 gtgattgctg caaccttgcc catctttata ggtctctttt tcaagaaacg ctttgcctgg
    54001 tatgaagtgt tggtaagtct cttctttatt gtcaccatgt tggtgggtgg aaagaccaat
    54061 caactagctg ccttgggtat ttacctttgc tgggaaatat tgctcctgct tttctacaag
    54121 cattatcgaa aaagcaagga tggcaagtgg gtcttctact tagttagttt tctgtcccta
    54181 cttccgatta tctttgtcaa ggtgcaacca gctatcaatg gaacgcagtc tttgcttggg
    54241 ttcttgggaa tttcttacct gacctttcgt tcggttggga ttatcatcga gctgagagat
    54301 ggagtgatta aggattttac cctctgggaa ttcctccgtt tccttctctt catgccaact
    54361 ttctcgagtg gtccaatcga tcgttttaag cgatttaatg aaaattatca ggccattcct
    54421 gagcgagatg agttgatgga tatgctggat gaatctgtcc gctatatcat gcggggcttt
    54481 ttgtataagt ttatcctagc tcatgtttta ggagagacct tactacctcc tctgaagaat
    54541 ttagccttgc agtcaggtgg cttctttaat ctctatgcct tggcagttat gtatactttt
    54601 ggtctggagc tcttctttga ctttgcaggt tattctatgt ttgctttggc catctcaaac
    54661 ttgatgggaa tccgtagccc tatcaacttt aacaagccct ttttatcaag ggatttaaag
    54721 gagttttgga atcgctggca tatgagtctg tccttctggt tccgtgactt tgtctttatg
    54781 cgaatggtga tggtgttaac cagaaagaaa gtctttaaaa atcgtaatgt aacctcaagc
    54841 atggcctaca ttgtaaatat gctgattatg ggattttggc atggtgtgac ctggtactat
    54901 atcgcctatg gactctttca tggactaggc ttggtcatca atgatgcctg ggttcgcaag
    54961 aaaaaaacgc tcaataagga acggaaaaaa gcagggaagg ctgccctacc tgagaatcgc
    55021 tggattcagt tgcttggcat ggttgtcact ttccatgttg tcatgttgtc attcttaatc
    55081 ttttctggat tcttgaataa tctatggttt aaaaaataaa aggaaataaa atatggatat
    55141 caaatcagaa gttatcgaaa ttattgatga gttgtttatg gaagatgttt ctgacatgat
    55201 ggatgaagat ctttttgatg caggtgtctt ggatagtatg ggaacggttg agttgattgt
    55261 ggagattgag aaccgttttg acattcgtgt ccctgtaaca gagtttggtc gtgacgactg
    55321 gaatacagct aataaaatta tagctggtat tgtggagcta caaaatgctt aaacgcttat
    55381 ggatgatctt cggaccggtc ttgatagctg gtttgttggt ttttctgctc attttctttt
    55441 atcctactga gatgcgtcat aatctaggag ctgaaaagcg ttcagcggtg gctactacta
    55501 tcgatagttt taaggagcga agtcaaaaag tcagagcact atctgatcca aatgtgcgtt
    55561 ttgttccctt ctttggctct agtgaatggc ttcgttttga cggtgctcat cctgcggtat
    55621 tagctgagaa atacaatcgt tcctaccgtc cttatctttt aggacagggg ggagctgcat
    55681 cgcttaacca atattttgga atgcaacaga tgttaccaca gctggagaat aaacaagttg
    55741 tgtatgttat ctcacctcag tggttcagta aaaatggcta tgatccagca gccttccagc
    55801 agtattttaa tggagaccag ttgactagtt ttctgaaaca tcaatctggg gatcaggcta
    55861 gtcaatatgc agcgactcgc ttactgcaac agttcccaaa cgtagctatg aaggacctgg
    55921 ttcagaagtt ggcaagtaaa gaagaattgt cgacagcaga caatgaaatg attgaattat
    55981 tggctcgttt taatgaacgc caagcctcct tttttggtca gttttcggtt agaggctatg
    56041 ttaactacga taagcatgta gctaagtatt taaaaatctt gccagaccag ttttcttatc
    56101 aagcaataga agatgttgtc aaagcagatg ctgaaaaaaa tacttccaat aatgagatgg
    56161 gaatggaaaa ttatttctat aatgagcaga tcaagaagga tttgaagaaa ttaaaggatt
    56221 ctcagaaaag ctttacctat ctcaagtcgc cagagtataa tgacttgcag ttggttttaa
    56281 cacagttttc taaatctaag gtaaacccga tttttatcat tccacctgtt aataaaaaat
    56341 ggatggacta tgctggtcta cgagaggata tgtaccaaca aacggtgcag aagattcgct
    56401 accagttaga aagtcaaggt tttaccaata tagcagattt ttctaaggac ggtggggagc
    56461 ctttctttat gaaggacacc attcaccttg gttggttggg ttggttggct tttgacaagg
    56521 cagttgatcc tttcctatcc aatcccacac cagctccgac ttaccatctg aatgagcgct
    56581 ttttcagcaa agattgggcg acttatgatg gagatgtcaa agaatttcaa tagataatat
    56641 aatatagaag agttcaagaa tgaaactagt tttcacgttt tttcttgact ctttttttgc
    56701 ttgtgatata attaactggt aaacaaaatg tcaaagaata gtatttttct cttaaaaaag
    56761 agaagtctaa aaggaaagga gtcagatatg agacagctag caaaggatat cgatgctttt
    56821 ttgaatgagg tgattttgca ggcggaaaat cagcatgaaa tcctaatagg tcattgcact
    56881 agcgaggtgg ccctgaccaa tactcaggag catatcctta tgctcttgtc agaggaatct
    56941 ttaacaaatt cagaattggc ccgtcgtctc aatgtcagtc aggcggcagt taccaaggcc
    57001 attaagtctt tggtcaagga agggatgttg gaaacatcta aagattctaa agatgcgcgt
    57061 gtgatttttt atcagttgac tgacttggct cgtccaatcg ctgaggagca ccaccatcac
    57121 catgagcata cacttttaac ctatgaacaa gtggcgactc agtttactcc aaatgaacaa
    57181 aaagtgattc agcggttttt gactgcttta gtaggagaaa tcaaataatg agatatatta
    57241 cggtagagga tttgtccttc tattatgata aggagcctgt tcttgaacat atcaattata
    57301 gtgttgatag tggggaattt gttaccttga ctggggaaaa tggagcggct aagacgacgc
    57361 tcatcaaggc tagtcttgga attctgcaac cacgcattgg aaaggtggct atttcaaaga
    57421 caaatacgca aggtaagaaa ttgagaatag cctatcttcc tcaacaaatt gccagtttta
    57481 atgctggttt tccaagtacg gtctatgaat ttgtcaagtc gggtcgctat ccgagaaaag
    57541 gctggttccg tcgtttgaat gctcatgatg aggagcatat caaggccagt ctggactcag
    57601 ttggcatgtg ggaacatcga gacaaacgct tggggtctct atctggggga caaaagcagc
    57661 gagcggtgat tgcgcgtatg tttgcttctg accctgatgt gtttatccta gacgagccaa
    57721 caacggggat ggatgcagga agtaaaaatg aattttacga actcatgcac cacagcgccc
    57781 atcatcatgg caaggctgtt ttgatgatta cccatgaccc tgaagaagtt aaggattatg
    57841 cggatcgcaa tattcatcta gtccgtaacc aagactcgcc atggcgttgt ttcaatgttc
    57901 atgagaatgg ccaggaggtg ggccatgctt agtttattat cttacgactt tatacaacgc
    57961 gcctttttgg cggttattgc tatgagtctt ttctcaccgg tattgggaac cttcctcatc
    58021 ttgcgtcgtc agagtttgat gagtgatacc cttagccacg tctcactttc aggtgtagcc
    58081 tttggtctgg ttttggggat ttctccaact atttctacta ttgccattgt cttgattgcg
    58141 gcggtctttc tggagtatct ccgtacggtt tacaagagct ttatggaaat cgggacagct
    58201 atcctcatgt caacaggtct ggctgtttct ctgattgtca tgagcaaggg taaaagctcg
    58261 agttcaatga gtttggacca atatctcttt ggttcgatcg tgactatcag tgaagaacag
    58321 gtcatttccc tctttgtcat tgcggcggtt gttttgattt tgacctttct ctttcttcgt
    58381 cctatgtata tcttaacttt tgacgaagat acggcctttg tggatggctt gccagttcgt
    58441 accatgtcca ttctttttaa catggtgaca ggggtggcta ttgcccttat gattcctgca
    58501 gcaggagctc ttctggtatc gaccattatg gtcttgccag ctagtattgc cctgcgtctg
    58561 gggaaaaact ttaaatcggt tatgctgctt gccagtgcga ttggcttttt gggaatggta
    58621 gcaggacttt acatttccta ctatgcagaa acacctgcaa gtgcaagtat taccattatt
    58681 tttgtaactg tctttatact aatcagttta gtaagacgtt ttatcaaata ggagacgaac
    58741 gtgaaaaaaa ttagcttatt actagccagt ctatgtgcct tgtttttagt ggcttgttcc
    58801 aatcaaaaac aggcagatgg taaactcaat atcgtgacaa ccttttaccc tgtctatgaa
    58861 tttaccaagc aagtcgcagg agatacggct aatgtagaac tcctaatcgg tgctgggaca
    58921 gaacctcatg aatacgaacc atctgccaag gcagttgcca aaatccaaga tgcagatacc
    58981 tttgtttatg aaaatgaaaa catggaaaca tgggtaccta aattgctaga taccttggat
    59041 aagaaaaaag tgaaaaccat aaaggcgaca ggcgatatgt tgctcttgcc aggtggcgag
    59101 gaagaagagg gagaccatga ccatggagaa gaaggtcatc accatgagtt tgacccccat
    59161 gtttggttat caccagttcg tgccattaaa ctagtagagc acattcgtga cagcttgtca
    59221 gcagattatc ctgataaaaa agagaccttt gagaagaatg cagctgccta tatcgaaaaa
    59281 ttgcaagcct tggataaggc ttacgcagaa ggcttgtctc aagcaaaaca aaagagcttt
    59341 gtgactcaac acgcagcctt taactatctt gccttggact atggactcaa acaagtcgca
    59401 atctcaggac tttctccaga tgcagagcca tcagctgctc gcttggcaga attgacagag
    59461 tatgtcaaga aaaataaaat cgcctatatc tattttgaag aaaatgcctc acaagccctt
    59521 gctaacacac tttcaaaaga agcaggtgtc aaaactgatg tcctcaatcc tttagaaagt
    59581 ctgacagaag aggacgccaa ggctggagaa aactacattt ccgtgatgga gaaaaacctc
    59641 aaggctttga aacaaacaac agaccaagaa ggcccagcaa tcgaacctga aaaggcagag
    59701 gataccaaga cagtccaaaa cggttatttc gaggatgcag ctgtcaagga ccgcaccttg
    59761 agtgactatg caggtaactg gcaatcagtt tatcctttcc ttgaagacgg cacgtttgac
    59821 caagtctttg actacaaggc taagttgact ggtaagatga cccaggctga gtacaaggct
    59881 tactatacaa aaggctatca gacagatgtg actaagatta acattactga taatactatg
    59941 gaatttgttc aaggtggaca aagcaagaaa tacacttaca agtatgtcgg taagaaaatc
    60001 ttgacttaca agaaaggcaa tcgtggcgtg cgtttcctct ttgaagccac agatgctgac
    60061 gctggacaat tcaagtatgt tcagtttagt gaccacaatg ttgccccagt taaggcagaa
    60121 catttccata tcttctttgg aggcacaagc caagaagctc tatttgaaga aatagataat
    60181 tggccaacct actatccaga taacctatct ggccaagaaa tcgcccaaga aatgttggcg
    60241 cattaatgag aaatcgacta gttcataaga gctagtcggt tttttgatac tagatggcta
    60301 acttcattat agacctttca gaactaaggg aacctgaaaa aataaataaa actcttgaaa
    60361 tatctgtact tatatgctag aatgtagtta gtgtataagg ttcattagaa caccaaagcc
    60421 cctaactagt gccatagtta agggcttttt tgacgtatct tagcgattta acgggtgttt
    60481 ataggctagt cagtcggtct acttcttacc atctagccat ttgcagacga aatacaagat
    60541 aattccagct ataacatctg ctataatagt aagagcaagc tctggtataa ggctcattag
    60601 tttcacctcc tctcacgaac ccataggaac gtaatcggta accgatgaca aaagtattat
    60661 accacactaa atttagatca tcaacttcac ttaatgcttg aactattgta gattatatgc
    60721 taaaatgtag ttaattgata aggttcatta gaacaccaaa gcccctaact atggccgtag
    60781 ttaagggctt ttttgacgta tcttagcgat ttaacgggtg tttataggct agtcagtcgg
    60841 tctactcctt actatctagc catctgcaga cgaaatacaa gataattcca gctataacat
    60901 ccgctataat agtaagagcg agctctatga taaggctcat tagtttcacc tcctctcacg
    60961 aacccatagg aacgtaatcg gtaaccgatg acaaaaatag tataccacaa tacatttaga
    61021 tcatcaaggt cacttaattc ttgaaatatc agatctaaga gaaaaatctt taaaatcaga
    61081 aaaacgcata atatcaggtg tgcaaaaact tgatactatg cgttttattg tgggaaggtt
    61141 tactccattt tctcctgaaa ttgagttttt gtccagcctc tgtttttggg gttgctgaga
    61201 aaataatgtc atgtggtgaa tatttgtaaa tcagtcagca gacagaacga tactcttcga
    61261 aaatctcttc acatcatgtc agcttcgtct ttccgtatat atgtgactga cttcatcagt
    61321 tctatctaca acctcaaaac agtgtttcga gctgacttca tcagttttca aatctgtact
    61381 ttgagcaagc tgagactagc ttcctatttg attttcattg aatatcagaa acccattctc
    61441 catcaaataa ttcgactgcg tctaataatt tttgatctgg cacggtgtct gaaataaagg
    61501 ttgtgtattt ggagagggga ttaattttaa aaaatccagt cttgtaaaat ttagaactat
    61561 caatcagtaa gatggtttca tgggctttgt caataatatt cttttttgaa atagcttggc
    61621 tgagagaagc ttcataaaca tattggtcat caatacctct tgctgaacaa aatgctaaat
    61681 cgatattaaa atgatctaat aaagaatttt ccttatcata gttgaccacg gaacaggatt
    61741 gatgtttgac ctcgccagat gtgataaaga ttttggagct atctttaaca gtttcagata
    61801 gggtttgtgc agtatgtaaa ccatttgtaa aaataatcaa attatcaagt tcagaaagat
    61861 agggacagag ttcgtagaca gtcgtactgg aatccagata gatacacata ccagaccgaa
    61921 taaagtcttt agcgagacta gcgattagtc ttttttgcct agtactttct ccttcacgta
    61981 tttgatgaga aagttcaatt gtgttcatag aggacagggt cacgtatccg tgctttcttt
    62041 tgataagacc ttgattttct aagaaaatta aatcacgacg taaggtactt gtgctggaga
    62101 aagtgatttc tgccagctct tttacggcaa ttcttttttt ctttttaata atttcaatca
    62161 attcaagtac acgttcatct tttatcataa gctcctccta atttatcatt tcaactatat
    62221 tatagcacaa attggaggaa tgtgaattat ttttatgaat attgggttaa catttgaaca
    62281 ttattcaagt aagcgttcac atattgaaaa aataaaatgt ggggattata ataaacttaa
    62341 tcaaggacga agagagaaga aaaatggaag cggttttagc aatagattta ggtgcgactt
    62401 ctggaagagc aatcgttggt tacctttctg aaaataaact agtaatggaa gaaataaatc
    62461 gcttttctaa tctacctatt agagtaaaag ggcatttatc ttgggatatt gactttctac
    62521 tagctaaaat tcttgaaagt atccgcttgg ctaatactag ttacaagatt ttatctatcg
    62581 gtattgacac atggggagtt gactttggac tgattgataa tgaaggtaag ctgttatcac
    62641 aacctgttca ttatcgtgat gaaagaacaa agggagtgtt aaaggaaata tctgaaatga
    62701 ctgaattaga aaaactgtat tcagagacag gaaatcagat tatggagata aataccttgt
    62761 ttcaactctt taaggcacgt caagaatctc ctgactcttt ctataagacc aataagattc
    62821 ttttaatgcc agatttgttt aattatctct tgacaggtaa gtttgctaca gaaaaaagca
    62881 ttgcttcaac aactcaatta tttgatccta ggagtcaaaa ttggaatcag aatatcttaa
    62941 aactatttga attggattca tctttacttc ctgaaattgt ttcagaggga aatgttcttg
    63001 gaaggataaa aaaggagtat ggtttaggcg atatttctgt tgtgaatgtt tgtagtcatg
    63061 atacagcaag tgcgattgtc tcagtaccta agacagaagg tagtttattt atttcatcag
    63121 gtacttggtc tttggttgga gtggaactta cttcaccgat tcttactacc gaatccttca
    63181 gttatggatt tacaaatgaa gtcggtaaag atggagtgat tacatttctg aagaattgta
    63241 cagggttgtg gatcatagag gaactaagac gttcgtttga acgaagaggg aaagcctatt
    63301 cttttgatga tattaggaca atggtggaga aagaaaaaga aaatcttcct ctgattgata
    63361 ctgaatcaac tgaatttgca acagaatctg atatgcacaa gactttgaca gaatatctag
    63421 cttatcatca tgaaactaga gagtggacag atggacaact atttaagatt gtttatgaaa
    63481 gcctagctga aacgtatagg aaagcgatag agttattaga agaactaact cataaggttt
    63541 ataagaggat atatgtgatt ggaggaggtg ctagagccag ttactttaac caaatgattg
    63601 ctgatagaac tggtaaagag gttcttacag gtttgactga gggtacagct gtggggaata
    63661 ttgttgtgca gctcatagct atgggacaat taaaagggat ggaagaagct caccatgtta
    63721 ttgaggagtt cctacaatta gagagttatt actcccaaaa gaattaaaaa gattgagagt
    63781 ttgtaaattt gcctccctcc cccttcttaa gttttgtaca agaagggggg ataattggtg
    63841 aattgaaaaa tatttagtgt tttgatatga ggaggacaag gatgtcagat gtaaaacaag
    63901 aattaattaa atatggtaag aagctagtag aaacagattt gacgaaagga acaggtggga
    63961 atctcagcgt tttcgatcgt gaaaaacaat tgatggcaat taccccgtcg ggtattgatt
    64021 tctttgaaat caaagaatcc gatattgtag tgatggatat taatggaaat gttgtagagg
    64081 gagaacgctt gccatctagc gaatggtata tgcatttgat tcaatatcaa actcgtgatg
    64141 atatcgatgc aattatccat gctcatacaa cttatgcaac agtattagct tgtctcagag
    64201 aaccacttcc agcgagtcat tatatgattg cagtggcagg gaaagatgtt cgggtagctg
    64261 agtatgcaac atatggcacg aaagaattgg ctgtgaatgc agctaaagca atggaaggtc
    64321 gtagagcagt tttactagcg aatcatggaa ttttagcagg tgcacaaaat ttattgaatg
    64381 catttaatat tgttgaagaa gttgaatatt gtgcaaaaat ttattgttta gctaagaatt
    64441 ttggagagcc agtagttctt cctgatgagg agatggaatt gatggcagaa aaatttaaaa
    64501 catacggtca gagaaaatag ggaggatatt aatgttaaaa catataccga aaaatatttc
    64561 tccagattta ttgaagactt taatggaaat gggacatgga gatgaaatag tattagctga
    64621 cgcgaattat ccttctgcct catgtgcaaa taagctaatt cgttgtgatg gcgtaaatat
    64681 tccagaatta ttagattcca ttctgtattt aatgccatta gatagttacg tcgatagttc
    64741 aattcagttt atgaacgttg tttcgggtga tgatattcct aagatatggg gtacctatag
    64801 acagatgatt gaaggtcatg gtacagatct taaaacgatt acttatctta gaagagaaga
    64861 cttttatgaa cgtagtaaga aagcttatgc tattgttgct acaggagaaa cttcacttta
    64921 tgctaatatt atccttaaga aaggagtagt tgttgaaaga gaaaatgttt aatagaggaa
    64981 ttttagttgc cagtcatggt gattttgcta gcggagctct catgaccgca gaaatgtttg
    65041 ttggtgagac aacaaatgat agagttagga cattaggttt gatgcctgga gagaatattg
    65101 tagagtttga gcattatttt aaaaatcaag tggatgaact gttagactca aatcaagagg
    65161 ttatcgtttt gactgacttg attggaggaa gtcctaataa tgtggctttg tcacggtttt
    65221 taaatttgga ttcagttgat attgtaacag ggtttaatat tcctctccta gtggaattaa
    65281 tatcaaatta tgattcaaaa atcaatttag aagaaattgt tcacaatgct caaaatagtt
    65341 tgtttaatgt taaacaacaa cttaacgtag aggaggaaga agatttatgt ctatagagtt
    65401 tgttcgtatt gatgaccgtc tggtacatgg tcaagttgtc actacgtggc taaaaaagta
    65461 tgatattgag caagttatca ttgttaatga tcgcatctca gaagataaaa cacgacaatc
    65521 tattttaaag atttctgcac cagtaggttt aaaaattgtt ttctttagtg taaaacggtt
    65581 tgtggaagtt ttaaactctg tgccaataaa aaagagaaca atgctgatat atacaaatcc
    65641 aaaagatgtg tatgattcta ttgaaggaaa tttaaaattg gagtacctca atgtaggaca
    65701 gatgagtaaa acggaggaaa atgaaaaggt aacgggaggt gtagctctag gtgaagaaga
    65761 caaatattat tttaagaaaa tagttgataa gggaacgaga gttgaaattc aaatggttcc
    65821 taatgataaa gttacaatgt tggaaaaatt tttataaaaa taatttaagg aggtacagta
    65881 tatgctattc acacaagcat tactggtgac attagttggg attattgcca ctattgacta
    65941 taatggaccg ttatttatga ttcaccgtcc gttagttaca agtgcaatgg ttggcttagt
    66001 cttaggagat ttcacccaag gtgttcttat tggttcagct cttgaattaa cttggctcgg
    66061 tgtaacaggt attggaggtt acactccacc agatactatt tcaggtgcga ttattggtac
    66121 tgcatttggt attttatctg gtcaaggaga aactgctggt atcgctatag cagttccaat
    66181 tgcagttgct acccaacagt tggatgttct tgcaaaaact ttagatgttt attttgtgaa
    66241 aaaagctgat aatgatgcta aaaacggaga ttattcaaag atcggttttt atcattattc
    66301 aagtttggtt ttaatcacgt tatttaaaat tgtaccaatt ttcctagcta ttatgcttgg
    66361 aggggaatat gtggcagact tgtttgctaa ggttccacca atcgttatgc agggacttaa
    66421 ctctgcaggt gctttactac cttcaattgg ttttggtatg cttttaaata tgatgctcaa
    66481 gaaaaatatg tgggtattct tgttgattgg attcatttgt tctgtgtatg gaggaatgtc
    66541 aaccattggg atctcactag ttggtattgc ggtagcatac ttctacgata tgattggaag
    66601 taaaccacaa gaaacaactt caagtagtga tgttgaggag gatcttgatc tatgatgaat
    66661 aataaagtaa ctaaagttga acttaaaaaa gttttcaaac gaagttttat gtatggttct
    66721 tcatggaact atgagagaat gcagaaccta ggttttctat atacaattct tccagtattg
    66781 aaaaaactat acccagacaa agattcagct tctcctgcaa tgaaacgtca ccttgagttt
    66841 ttcaatactc atcaaacagc ggcaccattt attcttggag ttacttccgc tatggaagaa
    66901 caagaaggaa atgaaggtgc agcttcaatt actggtatta aagttggctt gatggggcca
    66961 ctggctggtc taggagatag tttgttctgg ctgacactag ttcctatctg ttttagtatt
    67021 ggtgcgtctt attctaaaga cggcggtgct ttaggtatct ttatcgcctt aatattgttt
    67081 aatattatta atattcctgt taaatatttc ggtttgaaat atgggtatac taagggttct
    67141 agtcttatcc aagaaaataa tacaaaagga acattgaatc gcgttacgag tatggcgaca
    67201 gcattagggc tagtactagt gggtggtttg attccatcaa tggttggtat taattttgga
    67261 ttagaattta agcaggggga acttgttatt tctgttcaag aaatgattac aaaattaatt
    67321 ccaggattta tccctatggc tttgacttta ttaatgtgta aattaattag aaaaggaaag
    67381 aatccggttg tactaatctt tagtgttatg gctattggag ttatcctagt tgttttagga
    67441 attttgaagt agtagaaagt gtggaggtgg tatttgggat atcacctcca ttttggaaga
    67501 gaggtaaaga gtgaaattat ggtataagaa agctgcctca aattggaatg aagccttgcc
    67561 gattgggaac ggtcatttag gtggtatgat ttatggttca gctacaaaag aatgtattca
    67621 actaaacgat gagactattt ggtatagagg aaagtcagat agaaataatc cagactcact
    67681 attgcatctt aaaaaaattc gggaatatct tttagatgga gaaattcaga aagccgaaga
    67741 attgataaag ttaacaatgt ttgctacccc aagagatcaa agccactatg aattacttgg
    67801 ggaactttac attgagcata tagatattca gtcttgtgct ctttcattgt atgaaagaga
    67861 gctagattta gatacagcta tttctaatgt tgtgtttgag cctaatagtt gtaatttaca
    67921 aataaaaaga gaatatttta cgagttttaa taagaatatt ttatgttgcc gtatagtgtc
    67981 atcagttcaa aacacattaa atttaaacat taatttgggt agaaataaac ggtttaatga
    68041 tgaagtatct aaactggatt caagtacaat tttaatgtcg gcctctgctg gaggtagaaa
    68101 aggtgttcag tttaaagtag tatgtcattc taaggttacg gatggtgaag taagtgtatt
    68161 gggagagaca atagttattc ggaatgctac agaggtattt ctttatctca aatcaatgac
    68221 ggattattgg ggaaatatag atatttcttc tcttcaggga gaatttagta gtattgatta
    68281 ctttacagaa aaagatgaac atgtaaaaaa atatcaggag caatttaata gagttgattt
    68341 taaactagac tatagtaaag attgtcttag cattccaacg aatctacttc ttgaaaacac
    68401 taaaaagtat agtaactact tgactaactt gttatttcat tatggaagat atctgttaat
    68461 atcgtctagt caaccgaatg gtttacctgc caatcttcaa ggaatatggt gtgatgaatt
    68521 aaatccaatt tggggttcta aatatacgat taatattaat actcaaatga attattggat
    68581 ggtaggtcca tgtgatttac cagaagtaga atatccatta tttgatatgc tcgaaagaat
    68641 gagagaaccg ggaagactaa ccgctaagaa aatgtatgga gctagaggtt ttacagcaca
    68701 tcataatacg gatggttttg gcgatacggc tccccaatct catgccatgg gggctgcaat
    68761 ttgggtatta actattccat ggttatgtac tcatatttgg gaacactatt tatatttcca
    68821 agatgagcgt attcttacgg aacattttga aatgataaaa gaagcatttc ttttctttga
    68881 agattattta tttgaggtgg atggctactt gatgacaggt ccaagtgtct caccggaaaa
    68941 taaatatcgc ttaaaaaatg gtattgaagg aaatgcttgt ctatcatcta caattgataa
    69001 tcaaattcta agatattttt gtgattcatg cattggcatt gcaaaacaat taggagacaa
    69061 ttcggatttt attagtcgtg tgaaggagtt aaaaaagaaa ctacctaaaa caaaaatagg
    69121 tagtaatggg caaatccaag aatggttaga agattatgaa gaagtagagc ctgggcatag
    69181 acacatttca cctctatttg ggctttatcc ttataatgag attgatattc ataaaactcc
    69241 ggaattagca gaagcagcta aaatcactat caataggaga ttatcaaacg ctaacttttt
    69301 atcttcacag gagagggagc aagcgattaa taattggtta gtaagtggtt tgcatgctag
    69361 tacacaaaca ggttggagtg ctgcatggct gattcatttt tttgcgagac tatatcaagg
    69421 tgaacctgct tataaccaga ttaatggttt gttaaataat gcgactcttg gcaatttatt
    69481 tcttgaccat ccaccatttc aaattgatgg taatttaggt ttggtgagtg gaatttgtga
    69541 attattagta cagagccatc ataattggtt atcactaatt ccagctttac cttctgcttg
    69601 gtcagaagga gaagtgaaag gtttcagagt aagaggagga tataaggtat cgtttgcttg
    69661 gaaaaatggg gatataacat tcctaaaatt ggaaggagga aacaaagatc aaaaagtaag
    69721 agtaagaata tatggcaaaa atactgatgt acaaaatatt gaattggtat ttaattcaga
    69781 aaaaattatt gagttaaatt tttaggtata agtcatgaat aaagaaaaaa taaaaagaaa
    69841 attaatcaca atactgtttg tatgtattgg gatgttatgt tttggattgt tagcaggagt
    69901 taaggctgat aatcgtgttc aaatgagaac gacgattaat aatgaatcgc cattgttgct
    69961 ttctccgttg tatggcaatg ataatggtaa cggattatgg tgggggaaca cattgaaggg
    70021 agcatgggaa gctattcctg aagatgtaaa accatatgca gcgattgaac ttcatcctgc
    70081 aaaagtctgt aaaccaacaa gttgtattcc acgagatacg aaagaattga gagaatggta
    70141 tgtcaagatg ttggaggaag ctcaaagtct aaacattcca gttttcttgg ttattatgtc
    70201 ggctggagag cgtaatacag ttcctccaga gtggttagat gaacaattcc aaaagtatag
    70261 tgtgttaaaa ggtgttttaa atattgagaa ttattggatt tacaataacc agttagctcc
    70321 gcatagtgct aaatatttgg aagtttgtgc caaatatgga gcgcatttta tctggcatga
    70381 tcatgaaaaa tggttctggg aaactattat gaatgatccg acattctttg aagcgagtca
    70441 aaaatatcat aaaaatttgg tgttggcaac taaaaatacg ccaataagag atgatgcggg
    70501 tacagattct atcgttagtg gattttggtt gagtggctta tgtgataact ggggctcatc
    70561 aacagataca tggaaatggt gggaaaaaca ttatacaaac acatttgaaa ctggaagagc
    70621 tagggatatg agatcctatg catcggaacc agaatcaatg attgctatgg aaatgatgaa
    70681 tgtatatact gggggaggca cagtttataa tttcgaatgt gccgcgtata catttatgac
    70741 aaatgatgta ccaactccag catttactaa aggtattatt cctttcttta gacatgctat
    70801 acaaaatcca gctccaagta aggaagaagt tgtaaataga acaaaagctg tattttggaa
    70861 tggagaaggt aggattagtt cattaaacgg attttatcaa ggactttatt cgaatgatga
    70921 aacaatgcct ttatataata atgggagata tcatattctt cctgtaatac atgagaaaat
    70981 tgataaggaa aagatttcat ctatattccc taatgcaaaa attttgacta aaaatagtga
    71041 ggaattgtct agtaaagtca actatttaaa ctcgctttat ccaaaacttt atgaaggaga
    71101 tgggtatgct cagcgtgtag gt
//
LOCUS       DAVKBC010000005        66251 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVKBC010000005 DAVKBC010000000
VERSION     DAVKBC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.005"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..261)
                     /locus_tag="VWX64_000374"
     CDS             complement(<1..261)
                     /locus_tag="VWX64_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9189924.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNRKIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSS"
     gene            968..2443
                     /locus_tag="VWX64_000375"
     CDS             968..2443
                     /locus_tag="VWX64_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU9189925.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(2409..3124)
                     /locus_tag="VWX64_000376"
                     /pseudo
     CDS             complement(2409..3124)
                     /locus_tag="VWX64_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3380..4240
                     /gene="speE"
                     /locus_tag="VWX64_000377"
     CDS             3380..4240
                     /gene="speE"
                     /locus_tag="VWX64_000377"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU9189926.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            4237..5496
                     /locus_tag="VWX64_000378"
     CDS             4237..5496
                     /locus_tag="VWX64_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU9189927.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            5496..6623
                     /gene="nspC"
                     /locus_tag="VWX64_000379"
     CDS             5496..6623
                     /gene="nspC"
                     /locus_tag="VWX64_000379"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU9189928.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            6620..7705
                     /gene="aguA"
                     /locus_tag="VWX64_000380"
     CDS             6620..7705
                     /gene="aguA"
                     /locus_tag="VWX64_000380"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU9189929.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            7715..8590
                     /gene="aguB"
                     /locus_tag="VWX64_000381"
     CDS             7715..8590
                     /gene="aguB"
                     /locus_tag="VWX64_000381"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU9189930.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(8771..9580)
                     /locus_tag="VWX64_000382"
     CDS             complement(8771..9580)
                     /locus_tag="VWX64_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9189931.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            9853..10074
                     /locus_tag="VWX64_000383"
     CDS             9853..10074
                     /locus_tag="VWX64_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189932.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWQMEPVLTMP
                     VHGFCPRGTDDLGYIGGGNHLCKGSAARF"
     gene            10128..10799
                     /locus_tag="VWX64_000384"
     CDS             10128..10799
                     /locus_tag="VWX64_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9189933.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(10851..11039)
                     /locus_tag="VWX64_000385"
                     /pseudo
     CDS             complement(10851..11039)
                     /locus_tag="VWX64_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11032..11940
                     /locus_tag="VWX64_000386"
     CDS             11032..11940
                     /locus_tag="VWX64_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9189934.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKSQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11937..12398
                     /locus_tag="VWX64_000387"
     CDS             11937..12398
                     /locus_tag="VWX64_000387"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU9189935.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            12388..13275
                     /locus_tag="VWX64_000388"
     CDS             12388..13275
                     /locus_tag="VWX64_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9189936.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            13278..15161
                     /gene="cbpE"
                     /locus_tag="VWX64_000389"
                     /gene_synonym="pce"
     CDS             13278..15161
                     /gene="cbpE"
                     /locus_tag="VWX64_000389"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU9189937.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIELYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            15241..16371
                     /locus_tag="VWX64_000390"
     CDS             15241..16371
                     /locus_tag="VWX64_000390"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU9189938.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            16381..17643
                     /locus_tag="VWX64_000391"
     CDS             16381..17643
                     /locus_tag="VWX64_000391"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU9189939.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVAFPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            17647..18444
                     /gene="proC"
                     /locus_tag="VWX64_000392"
     CDS             17647..18444
                     /gene="proC"
                     /locus_tag="VWX64_000392"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU9189940.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            18664..19302
                     /locus_tag="VWX64_000393"
     CDS             18664..19302
                     /locus_tag="VWX64_000393"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU9189941.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            19299..20189
                     /locus_tag="VWX64_000394"
     CDS             19299..20189
                     /locus_tag="VWX64_000394"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU9189942.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQVNVSFQNAMEYLVLKEI"
     gene            20229..20546
                     /gene="yabA"
                     /locus_tag="VWX64_000395"
     CDS             20229..20546
                     /gene="yabA"
                     /locus_tag="VWX64_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU9189943.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            20549..21427
                     /gene="rsmI"
                     /locus_tag="VWX64_000396"
     CDS             20549..21427
                     /gene="rsmI"
                     /locus_tag="VWX64_000396"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU9189944.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASKGVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEENQEND"
     gene            21614..22948
                     /gene="trmFO"
                     /locus_tag="VWX64_000397"
     CDS             21614..22948
                     /gene="trmFO"
                     /locus_tag="VWX64_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU9189945.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            23032..23769
                     /locus_tag="VWX64_000398"
     CDS             23032..23769
                     /locus_tag="VWX64_000398"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU9189946.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            23778..24335
                     /gene="frr"
                     /locus_tag="VWX64_000399"
     CDS             23778..24335
                     /gene="frr"
                     /locus_tag="VWX64_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU9189947.1"
                     /translation="MANIIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            24395..25249
                     /gene="cvfB"
                     /locus_tag="VWX64_000400"
     CDS             24395..25249
                     /gene="cvfB"
                     /locus_tag="VWX64_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU9189948.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGCVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            25258..25472
                     /locus_tag="VWX64_000401"
                     /pseudo
     CDS             25258..25472
                     /locus_tag="VWX64_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
     gene            25558..26526
                     /locus_tag="VWX64_000402"
     CDS             25558..26526
                     /locus_tag="VWX64_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU9189949.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(26504..26683)
                     /locus_tag="VWX64_000403"
     CDS             complement(26504..26683)
                     /locus_tag="VWX64_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189950.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            26719..27219
                     /locus_tag="VWX64_000404"
     CDS             26719..27219
                     /locus_tag="VWX64_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9189951.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            27222..27482
                     /locus_tag="VWX64_000405"
                     /pseudo
     CDS             27222..27482
                     /locus_tag="VWX64_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(27849..28175)
                     /locus_tag="VWX64_000406"
     CDS             complement(27849..28175)
                     /locus_tag="VWX64_000406"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189952.1"
                     /translation="MVDVAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVT
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(28121..28534)
                     /locus_tag="VWX64_000407"
     CDS             complement(28121..28534)
                     /locus_tag="VWX64_000407"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU9189953.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(28535..28960)
                     /locus_tag="VWX64_000408"
     CDS             complement(28535..28960)
                     /locus_tag="VWX64_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU9189954.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            29137..29706
                     /locus_tag="VWX64_000409"
     CDS             29137..29706
                     /locus_tag="VWX64_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9189955.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGKFIGTIDLHKIDPVLKKVAIGYI
                     INQTYWNQGLTTETNRAVIELAFEKIGMNKLVALYDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            29774..30424
                     /locus_tag="VWX64_000410"
     CDS             29774..30424
                     /locus_tag="VWX64_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU9189956.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            30408..32648
                     /locus_tag="VWX64_000411"
     CDS             30408..32648
                     /locus_tag="VWX64_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU9189957.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLQLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVVKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQVTQTKVRSMTVGEYLPIFGSQLEVLSPRE
                     IGYGGHEDSLVLYGKLLNNHFLFIGNLEEKGEKDLLKYYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            32827..33015
                     /locus_tag="VWX64_000412"
     CDS             32827..33015
                     /locus_tag="VWX64_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189958.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            33047..33634
                     /locus_tag="VWX64_000413"
     CDS             33047..33634
                     /locus_tag="VWX64_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9189959.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            33638..34819
                     /locus_tag="VWX64_000414"
     CDS             33638..34819
                     /locus_tag="VWX64_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189960.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LRVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    34979..35110
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            35126..35656
                     /gene="infC"
                     /locus_tag="VWX64_000415"
     CDS             35126..35656
                     /gene="infC"
                     /locus_tag="VWX64_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU9189961.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            35689..35889
                     /gene="rpmI"
                     /locus_tag="VWX64_000416"
     CDS             35689..35889
                     /gene="rpmI"
                     /locus_tag="VWX64_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU9189962.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            35941..36300
                     /gene="rplT"
                     /locus_tag="VWX64_000417"
     CDS             35941..36300
                     /gene="rplT"
                     /locus_tag="VWX64_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU9189963.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            36358..36738
                     /locus_tag="VWX64_000418"
     CDS             36358..36738
                     /locus_tag="VWX64_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9189964.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            36988..37788
                     /locus_tag="VWX64_000419"
     CDS             36988..37788
                     /locus_tag="VWX64_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU9189965.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            37799..38737
                     /locus_tag="VWX64_000420"
     CDS             37799..38737
                     /locus_tag="VWX64_000420"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU9189966.1"
                     /translation="MTTNRLQVSLPGLDLKNPIISASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            38779..40812
                     /locus_tag="VWX64_000421"
     CDS             38779..40812
                     /locus_tag="VWX64_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU9189967.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGVKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDYHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDDFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(40873..42528)
                     /gene="pavA"
                     /locus_tag="VWX64_000422"
     CDS             complement(40873..42528)
                     /gene="pavA"
                     /locus_tag="VWX64_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU9189968.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQAGEPFANLSDLLDTYYKNKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            42633..43130
                     /gene="ybeY"
                     /locus_tag="VWX64_000423"
     CDS             42633..43130
                     /gene="ybeY"
                     /locus_tag="VWX64_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU9189969.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            43111..43506
                     /locus_tag="VWX64_000424"
     CDS             43111..43506
                     /locus_tag="VWX64_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU9189970.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            43523..44422
                     /gene="era"
                     /locus_tag="VWX64_000425"
     CDS             43523..44422
                     /gene="era"
                     /locus_tag="VWX64_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU9189971.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADLGYNEREY"
     gene            44471..45295
                     /gene="mutM"
                     /locus_tag="VWX64_000426"
     CDS             44471..45295
                     /gene="mutM"
                     /locus_tag="VWX64_000426"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU9189972.1"
                     /translation="MPELPEVETVCRSLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            45295..45900
                     /locus_tag="VWX64_000427"
     CDS             45295..45900
                     /locus_tag="VWX64_000427"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU9189973.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            45887..47086
                     /locus_tag="VWX64_000428"
     CDS             45887..47086
                     /locus_tag="VWX64_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU9189974.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            47086..47235
                     /gene="rpmG"
                     /locus_tag="VWX64_000429"
     CDS             47086..47235
                     /gene="rpmG"
                     /locus_tag="VWX64_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9189975.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            47275..47508
                     /gene="secG"
                     /locus_tag="VWX64_000430"
     CDS             47275..47508
                     /gene="secG"
                     /locus_tag="VWX64_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU9189976.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            47610..49964
                     /gene="rnr"
                     /locus_tag="VWX64_000431"
     CDS             47610..49964
                     /gene="rnr"
                     /locus_tag="VWX64_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU9189977.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            49927..50394
                     /gene="smpB"
                     /locus_tag="VWX64_000432"
     CDS             49927..50394
                     /gene="smpB"
                     /locus_tag="VWX64_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU9189978.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            50410..51270
                     /gene="tehB"
                     /locus_tag="VWX64_000433"
     CDS             50410..51270
                     /gene="tehB"
                     /locus_tag="VWX64_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU9189979.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEVMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            51343..52296
                     /gene="coiA"
                     /locus_tag="VWX64_000434"
     CDS             51343..52296
                     /gene="coiA"
                     /locus_tag="VWX64_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU9189980.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            52315..54117
                     /gene="pepF"
                     /locus_tag="VWX64_000435"
     CDS             52315..54117
                     /gene="pepF"
                     /locus_tag="VWX64_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9189981.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            54119..54832
                     /locus_tag="VWX64_000436"
     CDS             54119..54832
                     /locus_tag="VWX64_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU9189982.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            54899..55840
                     /gene="prsA"
                     /locus_tag="VWX64_000437"
     CDS             54899..55840
                     /gene="prsA"
                     /locus_tag="VWX64_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU9189983.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(55959..56300)
                     /locus_tag="VWX64_000438"
                     /pseudo
     CDS             complement(55959..56300)
                     /locus_tag="VWX64_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            56713..56808
                     /locus_tag="VWX64_000439"
                     /pseudo
     CDS             56713..56808
                     /locus_tag="VWX64_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(57061..57681)
                     /locus_tag="VWX64_000440"
     CDS             complement(57061..57681)
                     /locus_tag="VWX64_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9189984.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(57681..58163)
                     /locus_tag="VWX64_000441"
     CDS             complement(57681..58163)
                     /locus_tag="VWX64_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU9189985.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMILQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(58163..59005)
                     /locus_tag="VWX64_000442"
     CDS             complement(58163..59005)
                     /locus_tag="VWX64_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU9189986.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(59100..59900)
                     /locus_tag="VWX64_000443"
     CDS             complement(59100..59900)
                     /locus_tag="VWX64_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU9189987.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            60044..61423
                     /gene="glmU"
                     /locus_tag="VWX64_000444"
     CDS             60044..61423
                     /gene="glmU"
                     /locus_tag="VWX64_000444"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU9189988.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGSCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            61433..61978
                     /locus_tag="VWX64_000445"
     CDS             61433..61978
                     /locus_tag="VWX64_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9189989.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            61990..62304
                     /locus_tag="VWX64_000446"
     CDS             61990..62304
                     /locus_tag="VWX64_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU9189990.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            62321..63013
                     /locus_tag="VWX64_000447"
     CDS             62321..63013
                     /locus_tag="VWX64_000447"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU9189991.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            63090..63581
                     /gene="rocS"
                     /locus_tag="VWX64_000448"
     CDS             63090..63581
                     /gene="rocS"
                     /locus_tag="VWX64_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU9189992.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            63679..64269
                     /locus_tag="VWX64_000449"
     CDS             63679..64269
                     /locus_tag="VWX64_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU9189993.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            64278..66041
                     /locus_tag="VWX64_000450"
     CDS             64278..66041
                     /locus_tag="VWX64_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU9189994.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT        19848 a        12133 c        14945 g        19325 t
ORIGIN      
        1 gcttgatttc ttgaccgagc gcttgcgatt gttttcataa gactgttgag catagtcggc
       61 agaataaacc tctttgaagc gcccttttcc aagacattgt cggactgtcc cacgcttgat
      121 ttcagtgtgg atagtttgag gaacttttcc aagcagagag gcaatttttc tatttgattt
      181 cccttctttt ttccatcttt cgattaagcg acggctatcg attgtcaaat gtttggcttt
      241 tgtagtataa ttgtcttgca tctctgtgcc tttcttgtgt ttgtggttga acaacaagta
      301 taacacagag gtgttttctt atgcctacaa gagctatcag ctagttgaac catctaattt
      361 ttaggagggc tgggtggcta acttcattat agaactttca tttacgaaca tatagtaaaa
      421 tgaaacaaga acagaacaaa tcgatcagga cagtaaaatc tatttctaat aatgttttag
      481 aagcagaagt gtactattct agtttcaatc tattatattt ttgtttttta tcaaaaaata
      541 ctttacaagt tcttaaaaac atgatatagt aataaagctt agaaaatgag atgatgtttt
      601 ctagcaaata taaacccgag taaaaaatgc ctacggacag gcagggttga atgccgaagc
      661 gtggttgaaa agccacatta ttgatagggt taaaagccta cttttataag ttgatgttag
      721 gacacttgtc ctaattcata aatttttagt gtggtgaaag cacacgtcat cttgtgaaac
      781 gatcaataaa gtacgtaata tttgctacta gagagttagg aaacatcggg aacagacata
      841 ctcaacagaa accaaaataa acacgtcaga agattgcaga gcaggtgaaa acctgctctt
      901 ttttcatgag tcaaccttta gttccttagt tttcataagg tcctaaaaat attgaaagga
      961 gtatgttttg aaagagttag atcaaaacca agccccaatt tatgaggcct tggtgaagtt
     1021 acgcaagaaa aggattgttc cctttgatgt tccaggtcac aagcgtggac ggggaaatcc
     1081 agaacttgtc gaactcttag gagaaaaatg tgtaggcatt gatgtcaatt cgatgaaacc
     1141 cttggataat ttaggccatc ctatttcgat tattcgtgat gcagaggagc tggctgcaga
     1201 tgcttttgga gctagccatg cctttctaat gattggtgga acaacttcat cggtgcagac
     1261 tatgattctg gcaacctgca aggcaggaga taagattatt ctgccacgaa atgtccataa
     1321 atctgctatc aatgcgttgg ttctatgtgg tgccattccc atctatatcg agatgagtgt
     1381 agatcctaag attggtatcg ctttaggtct tgaaaatgac cgagtagcac aggccataaa
     1441 ggaccatcca gatgctaagg ctatcctaat caacaatcct acttactacg gcatctgttc
     1501 agacctaaag gggttgacag aaatggctca tgaagctggc atgatggttt tagtagatga
     1561 agcccatgga gcgcatttgc atttcactgg taaacttcca atttctgcta tggatgcagg
     1621 agctgatatg gcagcagttt ccatgcataa gtctggtggg agtttgacac aaagttcgct
     1681 tcttttaatc ggggagcaga tgaatcccga atacgttcgt cagattataa acctgaccca
     1741 gtctacatct gcctcttact tattgatggc tagtttggat atttcacgtc gcaacttggc
     1801 ccttcgtggt aaagagtcgt ttgaggaagt cattgagcta tccgagtacg ctcgtcatga
     1861 aatcaatgcc attggcggtt actatgctta ctcaaaagag ttaatagatg gtgtgtcggt
     1921 ctgtgatttt gatgtaacca agttgtcagt ttacactcag ggaataggct taacaggtat
     1981 cgaggtttat gacctcttgc gagacgaata cgacattcag atcgagtttg gtgatatcgg
     2041 caatatcttg gcctatattt ccatcggcga ccgcatccaa gacatcgagc gcttggttgg
     2101 tgctctggct gatattaaga gactctattc acgagatggg aaggacttaa tagctggaga
     2161 atatattcag cccgagttgg tgctgtctcc acaagaagcc ttctattcag agagaaaaag
     2221 tttgacctta gatgagtctg ttggacaggt ctgtggagaa tttgtcatgt gctatcctcc
     2281 agggattcct atcttggctc ctggtgaacg cattacacga gaaattgtag actatatcca
     2341 attcgccaag gaacgtggtt gctccctcca agggacggaa gatccagagg tcaatcatat
     2401 caacgttatt aagagaaaga caaactataa gaaaagtcaa tagttttatc taaactattt
     2461 cttatttcaa tttgatgatt tggcgatgat tttagagcac ggcaaaaagc ccttgaatta
     2521 gaagcggtca atcgcttaat ttctatcagc ttatcaaatc ctgcctcaat ccttttctga
     2581 ggattagggt agcgtgtcaa gagttggtag gtatattctg aatgctttcc aacgatttta
     2641 tccaactcag gaaagatgat atcaagacaa cgagtgtatt gtactttcca atcagactgt
     2701 ttttcttgag acgatgaata tgtctagcca gtatttttag ttctacttgc cgattatcgt
     2761 gttgaaattg ttcacgattg gggtcagaaa gaagtttaag agcgatgcca tgagcgtctt
     2821 tcttatccgt tttagtcttg cgaagtgata atgatttggc aaattccttg atgagcaaag
     2881 gattgcaggt gtaaacttta tatccttgtt catgcaggaa gttcagtaga ttaaaggcat
     2941 aatgtccggt attttcaaga gcgatgagac agtcttggtt gagctgtcga agagacagat
     3001 ctaagagttc aaaaccagct ttattatttg aaaaagtgag tggtttaaga acagtttttc
     3061 ctggaacatt caaggctgta acatcgtgtt tatttttagc gacatcaatg cccacataaa
     3121 gcatgggagt acctccagat gtagtatttc aagtctactt ggttatccac gaattttttg
     3181 ccttgttacc ttagacgaga taaaacgtct atgcgttatc aaactcatta ccaattgaaa
     3241 caaaaaactg tggttagagc ctttcggaaa tcgtcaagcg attggaggga ataaactaat
     3301 ccacagtggc ttattccaag tataccactt gggctttggc agtagctaac tgcgctaaat
     3361 ataatataag gagaaataga tggatttatg gttttctgaa gttcatactc cagatgtcaa
     3421 attgtctctg agaacagcca agcaacttta cgctggaaaa agtgaatggc aggatatcga
     3481 agtcttggat acgccagctt ttgggaaaat actgatttta aatggccatg tcttgttctc
     3541 agatgcggat gatttcgtct acaatgaaat gaccgttcac gttcccatgg ctgtccaccc
     3601 aaatccaaag aaagtattgg ttattggggg tggtgacggc ggtgttgccc aagtattaac
     3661 actctatcct gaactggaac aaatcgatat cgtggaaccg gatgagatgt tggtcgaggt
     3721 ctgtcgtgag tatttcccag actttgctgc agggctagat gatcctcgtg ttaccattta
     3781 ctaccaaaat gggctacgct ttttgcgaaa ctgcgaagat gattacgata ttatcatcaa
     3841 cgatgcgaca gatccatttg gccatacgga aggactcttt accaaggaat tctacggcaa
     3901 tagttatcga gctctgaagg aagacggcat catgatttac cagcatggga gtcccttctt
     3961 tgacgaggat gagtcggcct gccgaagcat gcaccgcaag gtcaatcaat cctttccaat
     4021 cagtcgggtt tatcaggccc atattccaac tagcccagct ggctattggt tgtttggatt
     4081 tgcatcgaaa aaataccacc ctgtcaaaga ttttgacaag gaaggttgga aaaaacgcca
     4141 gcttttcaca gaatactaca ctgcaaactt acacgtggga tcctttatgt tgcccaagta
     4201 tgttgaggac attttagaag aagaggaagg aaaaaaatga gtcgtttact agttattggt
     4261 tgtgggggcg ttgcccaagt tgctatttca aagatttgtc aagatagcga aacatttaca
     4321 gagattatga ttgctagccg taccaagtca aaatgcgatg acttgaaagc gaagctagaa
     4381 ggcaaaacaa gtactaaaat tgaaactgca gcacttgatg ctgacaaggt tgaagaagtg
     4441 attgccctga ttgaaagcta caaaccagaa gctgttttga atgtagctct gccttatcaa
     4501 gatttaacca ttatggatgc ttgtttggca acaggtgttc actatatcga tacagccaac
     4561 tacgaagcag aagacacaga agaccctgag tggcgtgcta tctacgaaaa acgttgtaag
     4621 gaacttggtt ttacagccta ctttgactac tcatggcagt gggcttatca agagaaattc
     4681 aaagaagcag gcttgactgc tcttcttggt tctggctttg acccaggtgt aactagtgtc
     4741 ttttcagctt atgccctcaa acactatttt gatgaaatcc attatatcga cattttagac
     4801 tgtaatggcg gtgaccacgg ttatccattt gcaaccaact ttaatccaga aattaatctc
     4861 cgtgaggttt ctgcgccagg ttcttactgg gaagatggga aatgggtcga agtcgaagct
     4921 atgtctatca agcgtgagta tgatttccct caagttggac aaaaagatat gtatctcctt
     4981 caccatgaag aaatcgaatc attggccaag aacattccag gtgtcaaacg cattcgtttc
     5041 tttatgactt ttggtcaatc ttacttgacg cacatgaaat gtcttgaaaa tgttggactc
     5101 cttcgtacgg ataccattaa ctttaacggc caagaaattg ttccaattca atttttgaaa
     5161 gccttgcttc cagatcctgc tagccttggc ccacgtactg taggtaaaac caatattgga
     5221 tgtatcttta caggtgtcaa agatggcgtt gaaaagacta tctacatcta caatgtttgc
     5281 gaccatcaag agtgctatgc agaagtcggg tcacaagcaa tttcatacac gacaggcgtt
     5341 ccagccatga ttgggacaaa attagtcatg aacggaactt ggaaacaagc tggagtgtat
     5401 aaccttgagg agttagatcc agatccattc atggaagctt tgaatgagta tggtttgcca
     5461 tgggttgtgg ttgaaaatcc acaaatggtg gactaatgaa gttagaacaa gtaccaacac
     5521 cagcctatgt tattgacttg gccaagttag aagctaattg ccgcattcta caatatgtac
     5581 aagaagaggt cggttgcaag gtcttgcttg cccagaaggc atattccctc tacaaaactt
     5641 atcccttgat tagccagtat ctatcaggta cgacagctag tggactctat gaggccaaat
     5701 tggcaaggga agaatttcct ggtgaagtcc atgtatttgc gcctgctttc aaggatgcag
     5761 acttggagga attgcttggg ataacagacc atatcgtctt taactcagag agacagttgc
     5821 gtaagcatgg ggctcgttgt cgagaggctg gtgtcagtgt tggtttgcgc ctcaaccctc
     5881 agtgttcaac tcaaggagat cacgcgctct atgacccttg tgcaccaggt tctcgctttg
     5941 gagttactat agacaagatt ccgagtgatt tgctagattt ggttgacgga cttcattttc
     6001 ataccctttg cgagcaggga gcagatgatt tacaaacaac tttgaaagca gtagaagaac
     6061 agtttggtcc ctacttacat gaggtaaaat ggctcaatat gggtggtggt catcatatta
     6121 caagagaagg ttacgatgtg gatttgctga tttcagaaat caagcgtatc cgaaaaactt
     6181 acaatcttga aatctatatc gagcctggtg aagccattgc gcttaatgcg ggttatttag
     6241 caactgaggt attagatatt gtagaaaacg gtatggaaat cttggtttta gacgcctctg
     6301 cgacctgcca tatgcctgat gtacttgaga tgccctatcg tccacctttg agaaatggct
     6361 ttgaggcaca ggaaaaagcc catacctaca gactttcttc taatacctgt ctgacgggcg
     6421 atgtgattgg tgattatagt tttgaaaatc cagtccaaat cggagacaga ctttattttc
     6481 aagacatggc catttattct tttgtcaaaa ataatacctt taatggtatt ggattgccaa
     6541 gtctctatct catggacgaa cagggagact gtagcttact caaagctttt ggctatcaag
     6601 actttaaagg gagattatca tgatggacag tccaaaaaaa ttaggctatc acatgccagc
     6661 agagtacgaa ccccatcatg gtaccctcat gatatggccg actcgaccag gatcatggcc
     6721 ttttcaagga aaggatgcta aaagagcatt tactcagatc atcgagacta tagcagaagg
     6781 ggaaagagtc tatcttttgg tggagcaggc ctatctatct gaagcccaat cctatcttgg
     6841 ggacaaggtt gtttatttag acattcccac caatgatgcc tgggcgcgtg atactggccc
     6901 aaccattctc gtcaatgata aaggtaagaa attagccgtg gattgggcct tcaatgcttg
     6961 gggaggcacc tatgatggtc tttatcaaga ttatgaagag gatgaccaag tagccagtcg
     7021 ttttgctgag gccttggaaa ggcctgtcta tgatgctaaa ccttttgtac tggaaggagg
     7081 cgcaatccat agcgatggtc aaggaactat tctcgtaact gaaagttgct tgcttagtcc
     7141 tggtcgcaat cctaacttga ctaaagagga gattgaaaac acattattag aaagtcttgg
     7201 tgctgaaaaa gttatttggc ttccttatgg tatttatcag gatgaaacca atgaacacgt
     7261 cgataatgtt gctgcctttg ttggtcctgc tgaggttgtt ttggcttgga cagatgacga
     7321 aaatgatccc cagtatgcca tgtcaaaagc agatctcgaa ctcttagaac aggaaacaga
     7381 tgcaaaaggt tgtcacttca ccattcataa attgcctatc cctgcagttc gacaagttgt
     7441 gacagaagaa gatttgccag gctacatcta tgaagaagga gaagaagagc gatacgcagg
     7501 tgaacgacta gcagcttcct acgtaaactt ttatatcgcc aacaaggctg tcttggttcc
     7561 acagtttgag gatgtaaacg accaagtggc cttagatatc ctcagcaagt gtttcccaga
     7621 ccgtaaagtt gtcggaatac cagccagaga tattctctta ggtggtggca atatccactg
     7681 tatcacccaa caaattccag aataggagaa aaagatgaga aatgtaagag ttgcaaccat
     7741 tcagatgcaa tgcgctaagg atgtggcaac aaatatccaa accgcagagc gtttagtacg
     7801 tcaggctgct gagcaaggag cccaaattat tctcttgccc gagttgtttg aacatcccta
     7861 tttctgtcag gaacgtcagt atgactacta ccagtatgcc caatctgtag cggaaaatac
     7921 tgccattcag cattttaagg tgattgctaa ggaactacaa gttgttttac caatcagttt
     7981 ctatgaaaaa gatggtaatg tcttgtataa ctctattgcc gtcattgatg cagatgggga
     8041 agtgctgggc gtttatcgaa agacccacat accagatgac cattattatc aagaaaaatt
     8101 ctatttcacg cctggtaaca ctggtttcaa ggtctggaat actcgctatg ctaagattgg
     8161 tatcggtatc tgttgggatc aatggttccc tgaaacagcc cgctgtcttg cattgaatgg
     8221 tgctgaattg ctcttttatc ctacagctat cggttcagag ccaattttgg atacagatag
     8281 ttgtggtcac tggcaacgta ctatgcaagg gcacgcagca gcgaatattg ttccagtcat
     8341 cgcagccaat cgttatggtt tagaggaggt tactcctagt gaggaaaatg gcggacagag
     8401 ttccagtctt gacttctacg gttcctcctt tatgacggat gaaacaggag ctattctaga
     8461 acgagctgaa agacaagaag aagctgttct gttagctact tatgacctag acaagggagc
     8521 aagtgaacgt ctaaactggg gcttgtttcg agatagaaga ccagaaatgt atagacaaat
     8581 tacagattag tgtgggagaa atgagagatt cattctgcta gactaacttc ttattagcaa
     8641 ctataagata ctatggcatc tagtaaatcg atttttatga ttcgctattc ttgtctattg
     8701 attagtccgt attttaaata ttagcaaaaa agcaaatagc agtaacttct gtctatttgc
     8761 ttttcttttt ttatagaata tatttctcaa tagcacgcgc aacgccgtct tcttcgttgc
     8821 ttgaggtaac ggcatccgca agagatttga cataatcgct ggcatttccc attgcaatcc
     8881 caagccctgc aaactggagc atttcgatat cgttattagc atcgcccatg gccataatct
     8941 ctgaggaatc aatcttcaaa atctcagcaa gtcgtgaaag agcagtagcc tttgtcgttc
     9001 caagtggcat tgcttcataa atgacaggct gcgaacgaac tccactgaat cgttggcaaa
     9061 gctcttcagc aaaacgctgc tcaaaatcgt ctgtttgttc ttttgttcct aaaaacatac
     9121 cttggaacat ccggaacttt ccactagtcg cttcttcaag agaaatttca gtcaggtctg
     9181 aaaatactag tttagcatca ttttcaataa cttgattggg cttgccaccg agaacaaaat
     9241 aatgtgactc gtcaaaaagt gtcaactgaa catcactctt ttcagcaagg tcatagaggt
     9301 attcgatgtc agctggactc agttcttgcc agtcaaccaa gccccagtcg ctagtctggt
     9361 gagttgaaca accgttgtta acaatcacat attcgttctg gaggtcgagt cccagttttt
     9421 tgtagtaggg gaggacaccg aaaagggggc gacccgtaca gagaaccagt ttgacacctt
     9481 tttcaatggc ttggtgaata gcagcgatgt gagcctgtgg gatttccttg gcttcattga
     9541 ggagggttcc atccatatcc aaggctagta gtttaatcat aggtcttcct tctttatctt
     9601 ttgctattat tatagcatat tttggagaag aaattgatag aaagcttgag actaattgat
     9661 tttatagttt aagatgtttt gatgacaatt catgatttga agaggatatt tggcaaagat
     9721 atgctatact atgtttgtca atgttgcaac tagacaaatt aaaaaaccaa cttaatataa
     9781 tagttttttt tgtaagtagg tatgagtagc agattactca actaatctaa acaataacgg
     9841 aggaaatata tcatgatttt aatgacaaaa aatataaatc taacaaatga agaattagag
     9901 ctgatacaag gtggagcaga tccctatggt aaagaaccta atggttatta tccttggcaa
     9961 atggaaccag tattaactat gccggttcat ggattttgtc ccagaggaac cgatgattta
    10021 ggatatattg gaggaggtaa tcatctttgc aaaggaagtg ctgcgagatt ttaagtaaaa
    10081 tttattagga atatgaagaa acaaggggag aaaacagagg atttaatatg aaaaaacggg
    10141 ctattcaaat tttactagca ttgtccttaa ttttttacaa atcaacttgg ttttggagag
    10201 ttttcaatca cctcgcaaag ccctatctac cagcaagtcg tgaatttttt cagattctgc
    10261 ttttgatgga gagcggagtt cttttcttag cggtcatcta tctactggtt tttgcaggaa
    10321 agaaaatttt tcatttcaag tggcagctga ggtacttcat ctacctttta ctgggctaca
    10381 tcatttcata tatgtctgac ttcctctttt cgtatttcat atccccgcct tcaaatcaaa
    10441 tttctttgaa tgaaacggta gaaatgatgg ggagacagga gttcccttat ttcttgctca
    10501 tcgtttgctt catcgcccct attgctgagg aattgattta tcgaggtgtg cttatgacaa
    10561 cctttttcaa aaactcacct tggtacggag atgttttgct ttctgctatt attttcggtt
    10621 atattcatat caattttgct ttaactcctc ttgctttttt catttatgct agtggaggtc
    10681 ttattttagc tctattgtat cgcatgacta aaaatctcta ctatccaata ctagttcata
    10741 ttctcattaa tatcactgcc ttctgggacg tgtggttgct cctattttca ggaagttagc
    10801 ttactaaaat aatgtcggaa ctttccagca ttttcttttt tcacaaatag tcaacgtttt
    10861 tctttccgat actgaagtgg tgtgtagcca cttatttttt tgaattgatt ttgaaaataa
    10921 ggttggcttg agaaaggcag atagtgaaga agaataggat gttctttttt cctttttgga
    10981 aaacttctaa aatatggtat aatgaaaaga taaagaagtt aggggtagaa gatgaacatt
    11041 caacaattac gctatgttgt ggccattgcc aatagtggta ctttccgtga agctgctgaa
    11101 aagatgtatg ttagtcagcc gagtctgtct atttctgttc gtgatttgga aaaagagttg
    11161 ggttttaaga ttttccgtcg gaccagctca gggactttct tgacccgtcg tgggatggaa
    11221 ttctatgaaa aatcgcaaga attggttaaa ggatttgata tttttcaaaa tcagtatgcc
    11281 aatcctgaag aagaaaaaga tgaattttct gttgctagcc agcactatga cttcttgcca
    11341 ccaactatta cggccttttc agagcgctat cctgactata agaacttccg tatttttgaa
    11401 tcaactactg ttcaaatatt agatgaagtg gcgcaagggc atagtgagat tgggattatc
    11461 tacctcaaca atcaaaataa aaaggggatt atgcaacggg ttgaaaaatt aggtctggag
    11521 gtcatcgaat tgattccttt ccatacccat atttatctcc gtgagggtca tcctttagcc
    11581 cagaaagagg aattagtcat ggaggattta gcggatttac caacggttcg tttcactcaa
    11641 gagaaagacg agtaccttta ttattcagag aactttgtcg ataccagcgc tagctcacag
    11701 atgtttaatg tgacagaccg tgccaccttg aatggtattt tggagcggac ggacgcctat
    11761 gcgacaggtt ctggattttt agatagtgac agtgttaatg gtattacagt tattcgtctc
    11821 aaggataacc tagataaccg catggtctat gttaaacgtg aagaagtgga gcttagtcaa
    11881 gctgggactc tcttcgtaga agtcatgcaa gaatattttg atcaaaagag gaaatcatga
    11941 aaaaaagagc aatagtggca gtcattgtac tgcttttaat tgggctggat cagttggtca
    12001 aatcctatat cgtccagcag attccactgg gtgaagtgcg ctcctggatt cccaatttcg
    12061 ttagcttgac ctacctgcaa aatcgaggtg cagccttttc tatcttacaa gatcagcagc
    12121 tgttattcgc tgtcattact ctggttgtcg tgataggtgc catttggtat ttacataaac
    12181 acatggagga ctcattctgg atggtcttgg gtttgactct aataatcgcg ggtggtcttg
    12241 gaaactttat tgacagggtc agtcagggct ttgttgtgga tatgttccac cttgacttta
    12301 tcaactttgc aattttcaat gtggcagata gctatctgac ggttggagtg attattttat
    12361 tgattgcaat gctaaaagag gaaataaatg gaaattaaaa ttgaaactgg tggtctgcgt
    12421 ttggataagg ctttgtcaga tttgtcagaa ttatcacgta gtcttgcgaa tgaacaaatt
    12481 aaatcaggcc aggtcttggt caatggtcaa gtcaagaaag ctaaatacac agtccaagag
    12541 ggtgatgtcg tcacttacca tgtgccagaa ccagaggtat tagagtatgt ggctgaggat
    12601 cttccgctag aaatagtcta ccaagatgag gatgtggctg tcgttaacaa acctcaggga
    12661 atggttgtgc acccgagtgc tggtcatacc agtggaaccc tagtaaatgc cctcatgtat
    12721 catattaagg acttgtcggg tatcaatggg gttctgcgtc cagggattgt tcaccgtatt
    12781 gataaggata cgtcaggtct tctcatgatt gctaaaaacg atgatgcgca tctagcactt
    12841 gcccaagaac tcaaggataa aaagtctctc cgcaaatatt gggcgattgt tcatggaaat
    12901 ctgcctaatg atcgtggtgt aattgaagcg ccgattggcc ggagtgaaaa agaccgtaag
    12961 aaacaggctg taactgctaa agggaagcct gcagtgacgc gttttcacgt cttggaacgc
    13021 tttggcgatt atagcttagt agagttgcaa ctggagacag ggcgcactca tcaaatccgt
    13081 gtccacatgg cttatatcgg ccattcagtc gctggtgatg aggtctatgg tcctcgcaag
    13141 actttgaaag gacatggaca atttcttcat gccaagactt taggttttac tcatccgaga
    13201 acaggtaaga ccttggaatt taaagcagat atcccagaga tttttaagga aaccttggag
    13261 agattgagaa agtaagaatg aaaaagaaat taactagttt agcacttgta ggcgcttttt
    13321 taggtttgtc atggtatggg aatgttcagg ctcaagaaag ttcaggaaat aaaatccact
    13381 ttatcaatgt tcaagaaggt ggcagtgatg cgattattct tgaaagcaat ggacattttg
    13441 ccatggtgga tacaggagaa gattatgatt tcccagatgg aagtgattct cgctatccat
    13501 ggagagaagg aattgaaacg tcttataagc atgttctaac agaccgtgtc tttcgtcgtt
    13561 tgaaggaatt gggtgtccaa aaacttgatt ttattttggt gacccatacc cacagtgatc
    13621 atattggaaa tgttgatgaa ttactgtcta cctatccagt tgaccgagtc tatcttaaaa
    13681 aatatagtga taatcgtatt actaattctg aacgtctatg ggataatctg tacggttatg
    13741 ataaggtttt acagactgct tcagaaaaag gtgtttcagt tattcaaaat atcacacaag
    13801 gggatgctca ttttcagttt ggggacatgg atattgagct ctataactat gaaaatgaaa
    13861 ccgattcatc gggtgaatta aagaaaattt gggatgataa ttccaattcc ttgattagtg
    13921 tggtaaaagt caatggcaag aaaatttacc ttgggggcga cttagataat gttcatggag
    13981 cagaagacaa gtatggtcct ctcattggaa aagttgattt gatgaagttt aatcatcacc
    14041 atgataccaa caaatcaaat accaaggatt tcattaaaaa tttgagtccg agtttgattg
    14101 ttcaaacttc ggatagtcta ccttggaaaa atggtgttga tagtgagtat gttaattggc
    14161 tcaaagaacg aggaattgag agaatcaacg cagccagcaa agactatgat gcgacagttt
    14221 ttgatattcg acaagacggt ttagtaaaca tttcaacttc ctacaagccg attccaagtt
    14281 ttcaagctgg ttggcataag agttcatatg gaaactggtg gtatcaagcg cctgattcta
    14341 caggagaata tgctgtcggt tggaatgaaa ttaagggtga atggtattac tttaaccaaa
    14401 cgggtatctt attacagaat caatggaaaa aatggaacaa tcgttggttc tatttgacag
    14461 actctggtgt tgctgctaaa aattggaaga aaatcgctgg aatctggtat tattttaaca
    14521 aagaaaatca gatggaaatt ggttgggttc aagataaaga gcagtggtat tatttggatg
    14581 ttgatggttc tatgaagaca ggatggcttc aatatatggg gcaatggtat tactttgctc
    14641 catcagggga aatgaaaatg ggctgggtaa aagataaaga aacctggtac tatatggatt
    14701 ctactggtgt catgaagaca ggtgagatag aagttgctgg tcaacattat tatctggaag
    14761 attcaggagc tatgaagcaa ggctggcata aaaaggcaaa tgattggtat ttctacaaga
    14821 cagacggttc acgagctgtg ggttggatca aggacaagga taaatggtac ttcttgaaag
    14881 aaaatggtca attacttgtg aacggtaaga caccagaagg ttatactgtg gattcaagtg
    14941 gtgcctggtt agtggatgtt tcgatcgaga aatctgctac aattaaaact acaagtcatt
    15001 cagaaataaa agaatccaaa gaagtagtga aaaaggatct tgaaaataaa gaaacgagtc
    15061 aacatgaaag tgttacaaat ttttcaacta gtcaagattt gacatcctca acttcacaaa
    15121 gctctgaaac gagtgtaaac aaatcggaat cagaacagta gtagaaaaga aggttttagg
    15181 gccttctttt tcctatcaac tcttttctat ttcctgttat tcatgttata atggataaat
    15241 atgaataatc ggagtgagac tatgaaatac aaacggattg tctttaaggt gggtacttct
    15301 tctctgacaa atgaggatgg aagtttatca cgtagtaagg taaaggatat tacccagcag
    15361 ttggctatgc tgcacgaggc tggtcatgag ttgattttgg tgtcttcagg tgccattgcg
    15421 gctggttttg gagccttagg atttaaaaag cgtccgacta aaattgctga taaacaggct
    15481 tcagcagcgg tagggcaggg acttttgttg gaagaatata cgaccaatct tctcttgcgt
    15541 caaatcgttt ctgcacaaat cttgctgacc caagatgact ttgtggataa gcgtcgttat
    15601 aaaaatgccc atcaggcttt gtcggttttg ctcaaccgtg gggcaattcc tatcatcaat
    15661 gagaatgata gtgtcgttat tgatgagctc aaggttgggg acaatgacac tctaagtgct
    15721 caagtagcgg cgatggtcca agcagacctt ttagttttct tgacagatgt ggacggtctc
    15781 tatactggaa atcctaattc agatccaaga gccaaacgct tggagagaat cgagaccatc
    15841 aatcgtgaga ttattgatat ggctggtgga gctggttcgt caaacggaac tgggggtatg
    15901 ttaaccaaaa tcaaggctgc aactatcgcg acggaatcag gagttcctgt ttatatctgc
    15961 tcatccttga aatcagattc catgattgag gcggcagagg agaccgagga tggttcttac
    16021 tttgttgctc aagagaaggg gcttcgtacc cagaaacaat ggcttgcctt ctatgctcag
    16081 agtcaaggtt ctatttgggt tgataaaggg gctgcggaag ctctctctca acatggaaag
    16141 agtcttctct tatctggtat cgttgaagca gaaggagcct tttcttacgg tgatatcgtg
    16201 acagtatttg acaaggaaag tggaaaatca cttggaaaag gacgcgtgca atttggagca
    16261 tctgctttgg aggatatatt gcgttctcaa aaagccaagg gtgtcttgat ttaccgtgac
    16321 gactggattt ccattactcc tgaaatccaa ctacttttta cagaatttta gaggtaaact
    16381 atggtgagta gacaagaaca atttgaacag gtacaggctg ttaaaaaatc gattaacaca
    16441 gctagtgaag aagtgaaaaa tcaagccttg ctagccatgg ctgatcactt agtggctgct
    16501 actgaggaaa ttttagcggc taatgccctc gatatggcag cggctaaggg gaaaatctca
    16561 gatgtgatgt tggatcgtct ttatttggat gcagatcgta tagaagcgat ggcaagagga
    16621 attcgtgaag tggttgcctt cccagatcca atcggtgaag ttttagaaac aagtcagctt
    16681 gaaaatggtt tggttatcac aaaaaaacgt gtagctatgg gtgtcatcgg tattatctat
    16741 gaaagccgtc caaatgtgac gtctgatgcg gctgctttga ctcttaagag tggaaatgcg
    16801 gttgttcttc gtagtggtaa ggatgcctat caaacaaccc atgccattgt cacagccttg
    16861 aagaagggct tggagacgac tactattcac ccaaatgtga ttcaactggt ggaagatact
    16921 agccatgaaa gtagttatgc tatgatgaag gccaagggct atctagacct cctcattcct
    16981 cgtggaggag ctggcttgat caatgcagtg gttgagaatg cgattgtacc tgttatcgag
    17041 acagggactg ggattgtcca tgtctatgtg gataaggatg cagacgaaga caaggcgctg
    17101 tctatcatca acaatgctaa aaccagtcgt ccttctgttt gtaatgccat ggaggttctg
    17161 ctggttcatg aagacaaggc agcaagcatc cttcctcgct tggatcaaat gctggttgca
    17221 gagcgtaagg aagctggact ggaaccaatt caattccgct tggatagcaa agcaagccag
    17281 tttgtttcag gtcaagcagc tgagacccaa gactttgaca ccgagttttt agactatgtc
    17341 cttgctgtta aggttgtgag cagtttagaa gaagcggttg cgcacattga atcccacagc
    17401 acccatcatt cggatgctat tgtgacggaa aatgctgaag ctgcagcata ctttacagat
    17461 caagtggact ctgcagcggt gtatgttaat gcctcaactc gtttcacaga tggaggacaa
    17521 tttggtcttg gttgtgaaat ggggatttct actcagaaat tgcacgcgcg tggtccaatg
    17581 ggcttgaaag agttgaccag ctacaagtat gtggttgctg gtgatgggca gataagggag
    17641 taagagatga agattggatt tatcggtttg gggaatatgg gtgctagctt ggcaaaatct
    17701 gtcttgcaga ctaggacgtc agatgagatt ctccttgcca atcgtagtca agctaaggta
    17761 gatgctttca ttgcagactt tggtggtcag gcttccagca atgaagaaat gtttgcagaa
    17821 gcagatgtga tttttctagg agttaagcct gctcagtttt ctgaactgct ttctcaatac
    17881 cagaccatcc ttgaaaaaag agaaagtctt cttttgattt cgatggcagc tggattgacc
    17941 ttagaaaaac tagcaagtct tatcccaagc caacaccgaa ttattcgtat gatgcctaat
    18001 acccctgctt ctatcgggca aggagtgatt agttatgcct tgtctcctaa ttgcagggct
    18061 gaggacagtg agatcttttg tcagctttta gccaaggctg gtctcttggt tgaattagga
    18121 gaaagcttaa tcaatgcagc gacaggtctt gcaggttgtg gaccagcctt tgtctatctc
    18181 tttattgagg ccttggcaga tgcaggtgtt cagacgggat taccacgaga aacagccttg
    18241 aaaatggcag cccaaactgt ggtaggagct gggcaattgg tcctagaaag ccagcaacat
    18301 cctggagttt tgaaagatca agtttgtagt ccaggcggtt cgactattgc tggcgtagca
    18361 agcctagaag cgcatgcttt tcgaggcaca gtcatggagg cagttcatca agcctataaa
    18421 cgaacacaag aactaggtaa ataagaggta gctttgactg cctcttttat ggtggttgat
    18481 actcttcgaa aatcaaattc aaactgcgtc agcttcacct tgccgtactc aagtacagcc
    18541 tgcggctagc ttcctagttt gctctttgat tttcattgag tatgaaatga gaagacaaaa
    18601 agattgtcac aaacccctat ttttttgata gaatagaagt agtaaaaaag aaatgagtta
    18661 gacatgtcaa aaggattttt agtctctctt gagggaccag agggagcagg caagaccagt
    18721 gttttagagg ctctgctacc aattttagag gaaaaaggag tagaggtgtt gacgacccgt
    18781 gaacctggcg gagtcttgat tggggagaag attcgggaag tgattttgga tccaagtcat
    18841 actcagatgg atgctaaaac agagctactt ctctatattg ccagtcgcag acagcatttg
    18901 gtggaaaaag ttcttccagc ccttgaagct ggcaagttgg tcatcatgga tcgttttatc
    18961 gatagttctg ttgcctatca gggatttggt cgtggcttag atattgaagc cattgactgg
    19021 ctcaatcagt ttgcgacaga tggcctcaaa cccgatttga cactctattt tgacatcgag
    19081 gtggaagaag gactggctcg tattgctgct aatagtgacc gcgaggttaa tcgtttggat
    19141 ttggaagggt tggacttgca taaaaaagtt cgtcaaggct acctttctct tctggataaa
    19201 gagggaaatc gcattgtcaa gattgatgct agtctccctt tggagcaagt tgtggaaact
    19261 accaaggctg tcttgtttga cggaatgggc ttggccaaat gaaacaagat caactaaagg
    19321 cttggcaacc agctcagttt gaccgttttg tccgtatctt agaacaagac cagctcaatc
    19381 acgcctatct cttttcaggt ttctttggaa gcttggaaat agcgcaattt ttagctaaga
    19441 gcctcttttg tacggataaa gttggcgtct taccatgtga gaaatgccga agttgcaagc
    19501 tgattgaaca ggaagagttt ccagatgtca ccttgattaa gccagtcaat caggtcatca
    19561 agacagaacg cattcgggaa ttggtgggac agttttctca agcagggatt gaaagccagc
    19621 aacaggtctt tatcatcgag caagcggata aaatgcatcc caacgcagcc aattctctgc
    19681 tcaaggtcat cgaagaaccc cagagtgaag tttatatttt cttcttgact agcgatgagg
    19741 aaaagatgtt accgacaatc cgaagtcgga cccagatctt ccactttaaa aagcaagaag
    19801 aaaaacttat cttactctta gaacaaatgg gacttgttaa gaaaaaagcg actcttttag
    19861 ctaagtttag tcaatcgcga gctgaagcag aaaagttggc taatcaggca agtttttgga
    19921 ccttggtcga tgaaagtgaa cgcctgctga cttggttagt agctaagaaa aaagaaagtt
    19981 atctacaggt tgccaaatta gccaacttgg cagatgataa ggaaaaacag gatcaggttt
    20041 tacggattct tgaagttctc tgtgggcagg acctcttgca ggtaagagta agagtgattc
    20101 tacaagattt actagaagct agaaaaatgt ggcaagttaa tgtcagcttt caaaatgcca
    20161 tggaatatct ggtcttgaaa gaaatataaa ctcaaaaatg aatgataaag aaaggaaagg
    20221 gctgttttat ggacaaaaaa gaattatttg acgcgctgga tgatttttcc caacaattat
    20281 tggtaacctt agccgatgtg gaagccatca agaaaaatct caagagcttg gtagaagaaa
    20341 atacagctct tcgcttggaa aatagtaagt tgcgagaacg cttgggtgag gtggaagcag
    20401 acgctcccgt caaggccaag catgttcgcg aaagtgtccg tcgtatttac cgtgatggat
    20461 ttcacgtatg taatgatttt tatggacaac gtcgagagca ggacgaagaa tgtatgttct
    20521 gtgatgagtt gttatacagg gagtaagcat gcaaattcaa aaaagtttta aggggcagtc
    20581 tccctatggc aagctgtatc tagtggcaac gccgattggc aatctagatg atatgacttt
    20641 tcgtgctatc cagaccttga aagaagtgga ctggattgct gctgaggata cgcgcaatac
    20701 agggcttttg ctcaagcatt ttgacatttc caccaagcag atcagttttc atgagcacaa
    20761 tgccaaggaa aaaattcctg atttgattgg tttcttgaaa gcagggcaaa gtattgctca
    20821 ggtctctgat gccggtttgc ctagcatttc agaccctggt catgatttag ttaaggcagc
    20881 tattgaggaa gaaattgcag ttgtgactgt tccaggtacc tctgcaggaa tttctgcctt
    20941 gattgccagt ggtttagcgc cacagccaca tatcttttac ggttttttac cgagaaaatc
    21001 aggtcaacag aagcaatttt ttggctctaa aaaagattat cctgaaacac agatttttta
    21061 tgaatcgccc catcgtgtgg cagatacatt ggaaaatatg ctagaagtct acggtgaccg
    21121 ctcggtagtc ttggttagag aattgaccaa aatctatgaa gaataccaaa gaggtacaat
    21181 ttctgaattg ctggaaagca tctctgaaac gtctctcaag ggtgaatgtc ttctgattgt
    21241 tgaaggtgcc agcaaaggtg tggaggaaaa ggatgaggaa gacttgttct tagaaatcca
    21301 agcccgtatc cagcaaggca tgaagaaaaa tcaagctatt aaggaagtcg ctaagattta
    21361 ccagtggaat aaaagtcagc tctacgctgc ctaccacgac tgggaagaaa atcaagaaaa
    21421 tgactaaaca gggaagtttg ccttcttccc tttttttgtt atactagtag aagaaaaaat
    21481 tagaaagatt tgtgggagtg aaaaagtcct gtggactttt tcagcctgag ccaagaaact
    21541 cgaaagctcg taagtctgat tggctttttc aatgtgaatc ttaacttcac actcccaaag
    21601 aggtattagt gtcgtgtctc aatcttatat caatgttatc ggtgctggtt tggcaggttc
    21661 tgaagcagct taccaaatcg cagagcgtgg tattccagtt aaactatatg aaatgcgtgg
    21721 tgtcaagtct acaccccagc ataaaacaga caattttgct gagttggttt gttccaattc
    21781 tttgcgtggg gatgctttga caaatgcagt tggtcttctc aaggaagaaa tgcgtcgctt
    21841 gggttctgtt atcttggaat ctgctgaggc tacacgtgtt cctgccggtg gagcccttgc
    21901 ggtggatcgt gatggtttct ctcaaatggt gaccgaaaaa gtggtcaacc accccttgat
    21961 tgaagtggtg cgtgatgaaa ttacagaatt gccaacagat gttattacag ttgtggcgac
    22021 tggtcccttg actagcgatg ccctggctga aaagattcat gcccttaata atggcgatgg
    22081 cttctatttc tacgatgcag cagcgcctat tatcgatgtc aacactatcg atatgagtaa
    22141 ggtctatctc aaatctcgtt atgataaggg agaagcagcc tatctcaatg ctccaatgac
    22201 caagcaagag tttatggatt tccatgaagc cttggtcaat gcggaagaag caccgctcaa
    22261 ttcttttgaa aaagaaaagt actttgaagg atgtatgcca atcgaagtta tggccaaacg
    22321 tggcattaaa actatgcttt atggccctat gaagccagtc ggtcttgagt atccggacga
    22381 ctacacagga cctcgtgatg gagaatttaa aacaccttat gcggttgtgc aacttcgtca
    22441 ggataatgca gctggtagcc tctacaatat cgttggtttc cagacccacc tcaaatgggg
    22501 agaacaaaag cgtgtcttcc aaatgattcc gggtcttgaa aatgcggagt ttgtccgtta
    22561 tggtgtcatg catcgcaatt cttacatgga ttcaccaaat cttcttgagc agacttaccg
    22621 ttccaagaaa caaccaaatc tcttctttgc tggtcagatg acgggggtgg aaggctatgt
    22681 tgagtcggcg gcttcgggct tagttgcggg aattaacgca gctcgtctct tcaaggaaga
    22741 aagcgaggtt attttccccg agacgacagc gattggaagc ttagctcatt acattaccca
    22801 tgccgacagc aaacatttcc aaccaatgaa tgtcaatttt gggatcatca aggagttgga
    22861 aggcgagcgt atccgtgata agaaggctcg ttatgaaaaa attgcagagc gtgcccttgc
    22921 cgacttagaa gaatttttga ctgtctaatt tttttgaaag aattgctcat gatactataa
    22981 aaatcttaga aattgtgata aaataggtag gatgaaagaa ggagagtgaa aatggcgaat
    23041 cccaagtata aacgtatttt aatcaagtta tcaggtgaag cccttgccgg tgaacgtggc
    23101 gtagggattg atatccaaac agttcaaaca atcgcaaaag agattcaaga agttcatagc
    23161 ttaggtatcg aaattgccct tgttattggt ggaggaaatc tctggcgtgg agaacctgca
    23221 gcagaagcag gtatggaccg tgttcaggca gattacactg gaatgcttgg gactgttatg
    23281 aatgctcttg tgatggcaga ttcattgcaa caagttgggg ttgatacgcg tgtacaaaca
    23341 gctattgcta tgcaacaagt ggcagagcct tatgtccgtg gacgtgccct tcgtcacctt
    23401 gaaaaaggcc gtatcgttat ctttggtgct ggaattggtt caccatactt ctcgacagat
    23461 acaacagcgg cccttcgcgc agctgaaatc gaagcagatg ccatcctcat ggctaaaaat
    23521 ggcgtcgatg gtgtgtacaa tgccgatcct aagaaggaca agacagccgt taagtttgaa
    23581 gaattgaccc accgtgatgt tatcaacaaa ggtcttcgta tcatggactc aacagcctca
    23641 accctctcaa tggacaacga cattgacttg gttgtcttca acatgaacca atcaggcaac
    23701 atcaaacgtg tcgtatttgg tgaaaatatc ggaacaacag tttcaaataa tatcgaagaa
    23761 aaggaataag aaagaatatg gctaacataa ttattgaaaa agctaaagag agaatgaccc
    23821 agtctcacca atcacttgct cgtgaatttg gtggtatccg tgctggtcgt gccaatgcaa
    23881 gcttgcttga ccgtgtacat gtagaatact atggagtcga aactcctctt aaccaaatcg
    23941 cttcaattac gattccagaa gcgcgtgttt tgttggtaac accatttgac aagtcttcat
    24001 tgaaagacat cgaacgtgcc ttgaacgctt ctgatcttgg tatcacaccg gctaatgacg
    24061 gttctgtgat tcgcttggtt atcccagctc ttacagaaga aactcgtcgt gaccttgcta
    24121 aagaagtgaa gaaggtcggc gaaaatgcta aagtggctgt ccgcaatatc cgtcgcgatg
    24181 ctatggacga agctaagaaa caagaaaaag caaaagaaat cactgaagac gaattgaaga
    24241 ctcttgaaaa agatattcaa aaagtaacag acgatgctgt taaacacatc gacgacatga
    24301 ctgctaacaa agagaaagaa cttttggaag tctaaaaata aacagaaaaa ctcagttggc
    24361 attgctggct gagttttatt cgaaagaagg aaatatgaat acaaatcttg caagttttat
    24421 cgttggactg atcatcgatg aaaatgaccg tttttacttt gtgcaaaagg atggtcaaac
    24481 ctatgctctt gctaaggaag agggccaaca tacagtaggg gatacggtca aaggttttgc
    24541 atacacggat atgaagcaaa aactccgcct gacaacctta gaagtgactg ccactcagga
    24601 ccaatttggt tggggatgtg tcacagaggt tcgtaaggac ttgggtgtct ttgtagatac
    24661 aggccttcct gacaaggaaa tcgttgtgtc actcgatatt ctccctgagc tcaaggaact
    24721 ctggcctaag aagggcgacc aactctacat ccgtcttgaa gtggataaga aagaccgtat
    24781 ctggggcctc ttggcttatc aagaagactt ccaacgtctt gctcgtcctg cctacaacaa
    24841 catgcagaac caaaactggc cagccattgt ttaccgtctc aagctgtcag gaacttttgt
    24901 ttacctacca gaaaataata tgcttggttt tattcatcct agcgagcgtt acgcagagcc
    24961 acgtttgggg caagtattag atgcgcgcgt tattggtttc cgtgaagtgg accgcactct
    25021 gaacctctcc ctcaaaccac gctcctttga aatgttggaa aacgatgctc agatgatttt
    25081 gacttatttg gaaagtaatg gcggtttcat gaccttaaat gataagtcat ctccagacga
    25141 catcaaggca acctttggca tttctaaagg tcagttcaag aaagctttag gtggtcttat
    25201 gaaggctggt aaaatcaagc aggaccagtt tgggacagag ttgatttagg gaggcttatg
    25261 agaaaatcat tttacacttg gctcatgacc gagcgcaatc ctaaaagtaa cagtcccaaa
    25321 gcaattttgg cagacctcgc ttttgaagag gcagcttttc caaaacatac agatgatttt
    25381 gatgaggtca gtcgcttttt ggaggagcat gccagtttct cttttaacct aggagatttt
    25441 gacagcattg gcaggaatat ctagaacact agcatttatt cattgggttt gggctagtaa
    25501 tttctccatc cctctgctat aataaaaaga aataaaagga ttagagaggt tctttatttg
    25561 aaggaacatt caatagacat tcaactgagt catccagatg acctgtttca tctttttggt
    25621 tccaatgaac gccatcttcg tttgatggaa gaagagcttg atgttgtgat tcatgctcgt
    25681 acggagattg tccaggtttt gggagaagag tctgcctgtg aggaagcccg tcaagttatt
    25741 caggctttga tggtcttggt aaatcgtggg atgaccgttg gtacgccaga tgtagtcact
    25801 gcgattagca tggtcaaaaa tgatgaaatt gacaagtttg tcgcccttta cgaagaagaa
    25861 attatcaaag ataatactgg gaaacctatc cgtgtcaaaa ccctagggca aaagctttat
    25921 gtggacagtg tcaaacagca tgatgtgacc tttggaattg ggccagcagg tacagggaag
    25981 accttccttg cagtgacctt ggcagtgact gcccttaaac gtgggcaagt caagcgaatt
    26041 atcctaactc gtccagcggt ggaagcggga gagagtcttg gatttcttcc gggtgatctt
    26101 aaggagaagg tggatcctta ccttcgtcct gtttacgatg ccttgtatca aattcttggg
    26161 aaagaccaaa cgactcgtct catggagcgt gaaattatcg aaattgcgcc ccttgcctat
    26221 atgcgtggcc ggaccttgga tgatgccttt gtcattctcg atgaggcgca aaacacgacc
    26281 atcatgcaga tgaagatgtt cttgacgcgt ttaggctttc attctaagat gattgtcaat
    26341 ggagatatca gtcagattga cctgccacgt aatgtcaagt ccggtttgat tgatgctcaa
    26401 gagaaactca agaacatcca tcagattgac tttgttcatt tttcagccaa ggatgtggtt
    26461 cgccatccag ttgtcgctca gattatccga gcctatgaat attctactga agttgcacac
    26521 gactgatttt gaggaagttc gcctgcaaaa gaatatactt ttgagagagg aaaatccagt
    26581 tgtataggct aaaggtttta tccaaaggtt tgagacaacg attaggcacg atggaaagaa
    26641 cttttatgtg gctgatgacg atcagtgcat cttcctgtgt cataatcaca gggcacaaga
    26701 aagtaggaat ttgaaaagat gattgaccaa ctatctaagt attacagttg taggatacta
    26761 actgaaaagg atattccaag tattttatct ttatatgaaa gtaatcctct gtattttcag
    26821 cattgtccac cagagccaaa ttttgcaact gtaaaagagg acatgctttg tctacctgaa
    26881 ggtaaagcta aggctgataa gttttttgtt ggattttgga atggatctga ccttgtggct
    26941 gttatggatt ttgtctatgc atatcctgat gaggagactg tttttattgg tttgtttatg
    27001 gttgatcaag cctatcagag gaaagggatt ggtagtcata ttgtgacaga agcactagct
    27061 tattttgcta agaactttcg aaaggcacgt ttggcttatg ttaagggaaa tccgcaatct
    27121 cagcattttt gggaaaagca gggctttaaa tcaattggat gcgaggttaa gcaagaactc
    27181 tatacggttg ttatcgctga acagagccta gaagattaga aatggcatca agtaagaact
    27241 atttggaatt tgttttggaa caattatcag gattagatga tgtgacttac cgttccatga
    27301 tgggggagta tattctttac ttccgcggca agattattgg cggcatttat gacgatcgct
    27361 ttttagttaa acccgtgcaa gcagtcttag ataagattga ccaatcttct tttgagtttc
    27421 catacaaagg tgccaaagaa atgatttgag tggaagaact tgataataag atgtttctat
    27481 aagacctgat tttagctatg tataaccaac tgccaacgcc caaacctaaa aagaaaaagc
    27541 aagggtgaac gaagtaaaaa agaagtctgc taaggccctg tctttgcacg ggtaaaattt
    27601 tatatataaa aagaagctgg gactaaagag ctcagcttcc tttggtttat ataattgtca
    27661 ttacaagacg aagtggttgg gcgaaactct gttgacttta ttcaatttag agtttcttat
    27721 gcacaattga gtctggaacg aaagtctcca gttgcaaagt atacagtata ataaaccaac
    27781 gatgtaatag ctgatgacac aaagcacagt gggtaggact tgcgaagtca cccttttctt
    27841 ttcaaaattt atactaaatc attgatatca gtgtagtcac gattaagtcc ttgagcaact
    27901 ggtaggctag tcaagtaacc ttgataagtg gtcacacctt gacgcaagcc ttcatcttca
    27961 gagattgctt gtgcgaatcc tttgccagcc aaagcttcga tataaggaag agtgacattg
    28021 gttagggcga tggttgaagt gcgggtaacc gcaccaggga tattggcaac ggcatagtgg
    28081 agaacaccgt gtttttcata gacgggttca tcgtgcgttg tcacacggtc agctgtttcg
    28141 ataaggccac cttggtcaac agcaacgtca acgatacaga gcctggacgc atttgtttga
    28201 ccatctcatc tgtcaccaat tccggtgctt ttgcaccagg gatgagaatg gctccaatca
    28261 ccacatcagc atctctcaca cttgcttcaa tgttgaatga attagatata agagtttgaa
    28321 tttgacttcc aaagacttct tctagaactg agagacgctt ggcactaata tctaaaatag
    28381 tcacttgagc accaagacca agggcgatgc gggcagcatg tgtaccgacg acaccatcac
    28441 cgatgatagt tacttttcct tttggaacac ctggtacacc accaggtaga acaccagagc
    28501 caccagcttg cttagtaagg aagtgagctc cgatttaaac agccatacga cctgcaacct
    28561 cactcatagg aacgaggagc ggtagttgtc cttgattgtc acgaacagtt tcataggcaa
    28621 ttcctgttgt ttttgctgct aacatagcat ctgctaattc tggagcagcg gccatgtgca
    28681 agtaggtgaa gagaagaaga tcgtcgcgca agtaaccgta ttcagaactt aaaggttctt
    28741 ttactttcac aaccaactct gctgcccaag cttcaccagc agtagcgaca atctcagctc
    28801 cttgcttttg atagtcagca tcagtaaagc cagaaccgag accagcattt gtttcgataa
    28861 ggacacgatg accacgacta actaagctat gaacacctgc aggtgtgagg gcgacacggt
    28921 tttcgttatt tttaatttct tttgggattc cgattaacat tgagataacc tacctttcaa
    28981 ttgacggtct tgttttggtt gtcacattcc agttcataaa tcaaaaatgt gacggtttca
    29041 ttgtatatga aaccgcttca aaaatcaaga aaaacttgtc atccaaattt ttttatgcta
    29101 gactagtgaa aatcaagctc taatggaggg aaaagtatgg aatcaatatt tgtgaaattt
    29161 gcccagtatc cgtctataga aacggagcgt ttattgctta gacctgtaac tttggatgat
    29221 gcggaagcaa tgtttgacta tgcctcggac aagggtaata cacgttacac ttttccaacc
    29281 aatcaaagct tggaagaaac caagaataac attgctcagt tctacttggc taatcccttg
    29341 ggacgttggg gaatagaact aaaaagcaat ggcaaattta tcggaacaat tgatttgcac
    29401 aagattgatc ctgttcttaa gaaggtagct attggttata ttatcaacca aacgtattgg
    29461 aatcaaggat taacgacaga aaccaatcgt gctgtgattg agctagcttt tgagaagata
    29521 ggaatgaata agttagttgc tttatacgat aaggctaatc ccgcatcagg aaaggtcatg
    29581 gagaaatcag gaatgcgttt ttcccatgca gaaccatatg cttgtatgga ccagcatgaa
    29641 aaaggccgaa tcgtgacaag agttcattat gtcttgacca aggaagacta ttttgcaaat
    29701 aaataagcag ttgaaaagaa atttttcgac tgttttttct tcctcttacg aataatctaa
    29761 gagaggagaa aatatggaag caattatcga gaaaatcaaa gagtataaaa tcatcgtcat
    29821 ctgtactggt ctgggcttgc ttgtaggagg atttttcctg ctaaaaccag ctccacaaac
    29881 acctgtcaaa gagacgaatt tgcaggctga agtcgcagct gtttccaagg atttggtatc
    29941 cgaaaaggaa gtgaacaagg aagaaaagga agaacccctt gaacaagatc taatcacagt
    30001 agatgtcaaa ggtgctgtca aatcgccagg gatttatgac ttgcctgtag gtagtcgagt
    30061 caatgatgct gttcagaagg ctggtggctt gacagagcaa gcagacagca agtcgctcaa
    30121 tctagctcag aaagttagtg atgaggctct ggtttacgtt cctactaagg gagaagaagc
    30181 agttagccaa cagactggtt tggggacagc ttcttcaata agcaaggaaa agaaggtcaa
    30241 tctcaacaag gccagtctgg aagaactcaa gcaggtcaag ggactgggag gaaaacgagc
    30301 tcaggacatt atcgaccatc gtgaggcaaa tggcaagttc aagtcagtag acgagctcaa
    30361 gaaggtctct ggcattggtg gcaaaacaat agaaaagctt aaagactatg ttacagtgga
    30421 ttaagaattt ctctattccc ctaatttacc tgagttttct attactttgg ctttattacg
    30481 ctattttctc agcatcttat cttgctttgt tgggctttgt ttttctgcta gtctgtctct
    30541 ttatccaatt tccgtggaaa tctgctggta aagttctaat aatttgcgga atctttggat
    30601 tttggtttgt ttttcaaaat tggcaacaga gtcaagcgag tcaaaatctg gcggattctg
    30661 ttgaaagggt acggattttg cctgatacta ttaaggttaa tggtgatagt ctatcctttc
    30721 gtggcaagtc taacggtcgt gctttccaag tctattataa actccagtcc gaggaggaga
    30781 aagaagcctt tcaagcttta accgacctgc atgagatagg actagaaggg aagctttcgg
    30841 agccagaagg gcagagaaat tttggtggct ttaattacca agcctatctg aagactcagg
    30901 gaatttacca gactctcaat atcaaaacaa tccagtcact tcaaaagatt ggcagttggg
    30961 atataggaga aaacttgtcc agtttacgtc gaaaggctgt ggtttggatt aagacgcact
    31021 ttccagaccc tatgcgcaat tacatgacag gactcttgct gggacatctg gacaccgact
    31081 ttgaggagat gaatgagctt tattccagtc taggaattat ccacctcttt gccctatctg
    31141 gcatgcaggt aggttttttc atgaatggat ttaagaaact tctcttgcaa ttgggcttga
    31201 cccaagaaaa gttgaaatgg ctgacttatc ccttttccct tatctatgcg ggactaactg
    31261 gattttcagc atcggttatt cgcagtctct tgcaaaagct actggctcaa catggggtta
    31321 agggcttgga taattttgcc ttgacggtgc ttgtcctctt tattgtcatg ccaaactttt
    31381 tcttgacagc aggaggagtc ttgtcctgcg cttatgcttt tatcctgacc atgaccagca
    31441 aagaagggga ggggctcaag gctgttgcta gtgaaagtct agtcatctcc ttgggcatat
    31501 tgcccattct atccttctat tttgcggaat ttcaaccttg gtctatcctt ttgacctttg
    31561 tcttttcctt tctatttgac ttgaccttct taccgctctt gtctatttta tttgtccttt
    31621 cctttctcta tccagtcatt cagctgaact ttatctttga atggttggag ggcattattc
    31681 gcttggtgtc acaggtgaca agtagacctc tggtctttgg acaacccaat gcatggtttt
    31741 taatcctatt gttaatttcc ttggctttgg tctatgattt gagaaaaaac attaaaaagc
    31801 taacggtatt gtgcttattg attacagggc tctttctcct gaccaagcat ccactggaaa
    31861 atgaaatcac catgctggat gtggggcaag gagaaagtat tttcctacgg gatgtaactg
    31921 ggaaaaccat tctcatagat gtaggtggta aggcagaatc ttataagaaa atcgaaaaat
    31981 ggcaagaaaa gatgacgacc agcaatgccc agcgaacctt gattccctat ctcaaaagtc
    32041 gaggagtagt taagattgac cagctaattt tgactaacac ggacaaggag catgttggag
    32101 atttgtcaga ggtgactaag gctttccatg taggggagat tctagtatca aaagacagtc
    32161 tgaaacagaa ggaatttgtg gcagaactac aggtgactca aacaaaggtg cgtagtatga
    32221 cagtagggga gtacttgccc attttcggaa gtcagttaga agtcctatct ccaagggaaa
    32281 ttggatatgg aggtcatgaa gattccctgg ttctttatgg gaaactcttg aataatcact
    32341 ttctcttcat aggaaatttg gaggagaaag gagagaagga cttgctgaag tattatccag
    32401 acttgaaagt aaatgttttg aaagctagcc aacatggcaa taaaaaatca tcaagtccag
    32461 cctttctaga aaaactcaaa ccagagctta ctcttatctc agttggaaag agcaatcgaa
    32521 tgaaactccc ccatcaggaa acattgacac gactggaagg tatcaatagc aaagtttatc
    32581 gaactgacca gcaaggagct atacgtttta aggggttgga tagttggaaa atcgaaagtg
    32641 ttcgatagga aggataaatg ttgtagatta gtgaaataaa ctaaaaattt gttgcataat
    32701 aatgataaaa atggtataat gaaaacgtat tcaatattga ggatataaaa tcattaaaaa
    32761 tcagcaaaag ttgttttatt agttagttta taatctattg gtcttcttca gtccagtgta
    32821 tctgctgtga cagccactaa aagttacaag tatgattgga atacggtttt ggaatatagt
    32881 accaactatc acgaccatca gtatgcttgg attccggaat ggtctcgtta ttacagctat
    32941 tctgagtata aagttggcgg aggctggaac tacgctcgtt atgaggtcat aaactactat
    33001 actggaggtt attaatcctt aaagagtgag aaaaggaggg ctggatatgt taaatcttac
    33061 tcatgttacc ttaaaaacgc gacaagtcat cttgcaagat gcggatttta cctttaaaaa
    33121 gggtaggatt tatggccttc ttgctatcaa tggctcggga aagacgacac tattccgagc
    33181 tatgagcaag ttgcttcccc ttagtagtgg acacatcgca gttcctcctt ctttgtttta
    33241 ttatgagagc gttgaatggc tggatggaaa cttaagtggg atggactacc ttcgtctcat
    33301 aaaaaacatc tggaagtcag acctaaactt gagagatgaa atcgcctact gggaaatggc
    33361 tgactatatc agtcttccca tccgcaagta ttccttaggg atgaagcaac gcttggtgat
    33421 tgctatgtat tttctcagtc aggccaaatg ctggctcatg gatgagatta caaatggctt
    33481 agacgagtat tatcgacaga agttttttga taggctagca caaatcgata gacaagaaca
    33541 gctggttctt ttaagttccc actataagga agagttggtt gatatctgcg atagagtagt
    33601 aaccattcat caggggcaga tagaagaggt ttagtttatg aaagatgtta gtctattttt
    33661 attgaaaaaa gttttcaaaa gtcgtttaaa ctggattatc ttacttttat ttgcatctgt
    33721 actcggtgtt accttttatt taaatagtca gactgcaaac tcacacagct tggagagcag
    33781 gttggaaagt cgcattgcag ccaacgagag ggctatcaat gaaaatgaag agaaactctc
    33841 ccaaatgtct gataccagct cggaggaata ccagtttgct aaaaataatt tagacgtgca
    33901 aaaaaatctt ttgacgcgaa agacagaaat tctaacttta ctaaaagaag ggcgctggaa
    33961 agaagcctac tatctgcagt ggcaagatga agagaagaat tatgaatttg tatcaaatga
    34021 cccgactgct agctctggct taaaaatggg ggttgaccgc gaacggaaga tttaccaagc
    34081 cctgtatccc ttgaacataa aagcacatac tttggagttt ccgacccacg ggattgatca
    34141 gattgtctgg attttagagg ttatcatccc aagcttgttt gtggttgcga ttatttttat
    34201 gctaacacaa ctatttgcag aaagatatca aaatcatctg gacacagctc acttatatcc
    34261 tgtttcaaaa gtgacatttg caatatcctc tcttagagtt ggagtgggat atgtaactgt
    34321 gctgtttatc ggaatctgtg gcttttcttt tctagtggga agtctgataa gtggttttgg
    34381 acagttagat tatccctacc caatttatag cttagtgaat caagaagtaa ctattgggaa
    34441 aatacaagat gtattatttc ctggcttgct cttagctttc ttagccttta tcgtcattgt
    34501 ggaagttgtg tacttgattg cttacttttt caagcaaaaa atgcctgtcc tctttctttc
    34561 actcattggg attgttggct tattgtttgg catccaaaca attcagcctc ttcaaaggat
    34621 tgcacatctg attcccttta cttacttgcg ttcagtggag attttatctg gaagattatc
    34681 taagcagatt gataatgtcg atctaaattg gagcatgggg atggtcttac ttccttgcct
    34741 gattatcctt ttgttagtgg ggattctatt tatcgaaaga tggggaagtt cacgtaaaaa
    34801 ggaagttttt aaagtttagt tttcctatag ggaagctaaa gaaaaactaa catagggaga
    34861 gaatcaactt ggttctctct ttttgattcg aaaaccaaac caaaatataa acacaaactt
    34921 ttcaaaaaat aactttttat cttgacaaga gctagaaaac ttggtatcat ataaaagttg
    34981 agaaaagcag aagtgagagc ttctcgcctt gtgacattaa gttgcctggc cctacggatg
    35041 aaaagtttcg aagaaacgct atcataacgt gcgggcttgt atatttacga gtccgctatt
    35101 gtttttctct aataaaacaa aagaggtgaa aaccatagca aagcaagact tattcatcaa
    35161 tgatgagatt cgtgtacgtg aagttcgctt gattggtctt gagggagaac agctaggcat
    35221 caagccactc agtgaagcgc aagctttggc tgataacgct aatgttgacc tagtattgat
    35281 tcaaccccaa gccaaaccgc ctgttgcaaa aattatggac tacggtaagt tcaaatttga
    35341 gtaccagaag aagcaaaaag aacaacgtaa aaaacaaagc gttgttactg tgaaagaagt
    35401 tcgtctaagt ccaactattg acaagggtga ctttgataca aaacttcgta atgcacgtaa
    35461 gttccttgaa aaaggaaata aagttaaggt atctattcgc tttaagggtc gtatgattac
    35521 ccataaagag attggtgcaa aagttttagc cgagtttgct gaagcaactc aagatattgc
    35581 catcatcgaa caacgtgcta aaatggatgg acgtcaaatg ttcatgcaat tggcgccagc
    35641 gactgacaaa aaataattgt cagaaagtta aataaaggag aaaaaatcat gccaaaacaa
    35701 aaaacacacc gcgcatcagc taaacgtttc aaacgtacag gttctggtgg acttaaacgt
    35761 ttccgtgctt acacttctca ccgtttccac ggaaaaacca agaaacaacg tcgtcatctt
    35821 cgtaaagcat ctatggtgca ttcaggagat tacaaacgta tcaaagcaat gcttactcgc
    35881 ttgaaataat agcttgactg taagtaaaca attctaggaa atatttggag gaaataaaat
    35941 atggcacgtg ttaaaggtgg cgttgtatca cgcaaacgtc gtaaacgtat tcttaaatta
    36001 gcaaaaggtt actatggagc taaacacatc ttgttccgta ctgcaaaaga acaagtaatg
    36061 aactcttact actatgcata ccgtgaccgt cgtcagaaaa aacgtgactt ccgcaaattg
    36121 tggattactc gtatcaatgc ggcagctcgt atgaacggac tttcatactc acaattgatg
    36181 catggtttga aattggctga gatcgaagtt aaccgtaaaa tgcttgctga cttggctgtt
    36241 aacgatgcag tagctttcac agctcttgca gatgcagcta aagcaaaact tggtaaataa
    36301 caactgatga gactggaaca ggattgtcca gtctttttaa aaataaagga gaaagatatg
    36361 gcttcaaaaa tgctacacac ttgcttacga gtagaaaatc ttgaaaaatc aatcgcattt
    36421 tatcaagatg cttttggttt taaagaattg cgtcgcagag attttccaga ccatgccttc
    36481 acgattgtct atctaggtct tgagggtgat gattatgagt tggagttgac ttataactac
    36541 gatcacggtc cgtatgtggt tggtgatggg tttgcccata tcgccctcag tacacctgat
    36601 cttgaggcac ttcatcaaga acacagtgca aaaggctatg aagtgactga gccaaatggt
    36661 ctaccaggaa ctacaccaaa ctattacttt gttaaagacc ctgatggata taaggtcgaa
    36721 gtcattcgtg aaaaataatt tcgtgcaagt taagtagaat attcgttttc tacttgactt
    36781 tttttagctg aaagagtata ctaataaaaa ttcaaccttt aaggggagtc cagagagact
    36841 cacaaggtgt cagataaaag aatagtgcaa ttttctagag gagacttttt gagtgtgctc
    36901 tcttgtgttg tacgatttta actgaggcct tgcactagca aggtcttttc tttatctggt
    36961 ccccttaaaa tttaaggagg aaaagttatg aatctcacat gtaagaagcg tttgggtgtc
    37021 attcggttgg aaaccatgaa ggtggttgca caagaggaaa tcgcgccagc aatctttgaa
    37081 ttagtcctag aaggagaaat ggttgaagcc atgcgagcag gccaatttct tcatctgcgt
    37141 gtaccggacg atgcccatct cttacgtcgt cctatttcaa tttcgtctat tgacaaggca
    37201 aacaagcagt gtcacctcat ttatcggatt gagggagctg ggactgcaat tttttcaacc
    37261 ttaagtcagg gagacactct tgatgtgatg gggcctcagg gaaatggttt tgacttgtct
    37321 gaccttgatg agcagaatca ggttctcctt gttggtggtg ggattggtgt tccacccttg
    37381 cttgaggtgg ccaaggaatt gcatgaacgt ggagtgaaag tagtgacagt cctcggtttt
    37441 gctaataagg atgctgttat tttgaaaacg gaattggctc agtatggtca ggtctttgta
    37501 acgacagatg atggttctta tggcatcaag ggaaatgttt ccgttgttat caatgattta
    37561 gatagtcagt ttgatgctgt ttactcgtgt ggggctccag gaatgatgaa gtatatcaat
    37621 caaacctttg atgatcaccc aagagcctat ttatctctgg aatctcgtat ggcttgtggg
    37681 atgggagctt gctatgcctg tgttctaaaa gtaccagaaa gcgagacggt cagccaacgc
    37741 gtctgtgaag atggtcctgt tttccgcaca ggaacagttg tattataagg agaaaattat
    37801 gactacaaat cgattacaag tgtctctacc tggtttggat ttgaaaaatc cgattatttc
    37861 agcatcaggc tgttttggct ttggacaaga gtatgccaag tactatgatt tagacctttt
    37921 aggttctatt atgatcaagg cgacaaccct tgaaccacgt tttgggaatc caactccaag
    37981 agtggcagag acgcctgctg gtatgctcaa tgcaattggc ttgcaaaatc ctggtttaga
    38041 ggttgttttg gctgaaaagc taccttggct ggaaagagaa tatccaaatc ttcctattat
    38101 tgccaatgta gctggttttt caaaacaaga gtatgcagct gtttctcatg ggatttccaa
    38161 ggcaactaat gtaaaagcta tcgagctcaa tatttcttgt cccaatgttg accactgtaa
    38221 tcatggactt ttgattggtc aagatccaga tttggcttat gatgtggtga aagcagctgt
    38281 ggaagcctca gaagtgccag tttatgtcaa attaaccccg agtgtgaccg atatcgttac
    38341 tgtcgcaaaa gctgcagaag atgcgggagc aagtggctta actatgatca atactctggt
    38401 tggaatgcgc tttgacctca aaactagaaa accaatcttg gccaatggaa caggtggaat
    38461 gtctggtcca gcagtctttc cagtagccct caaactcatc cgccaagttg cccaaacaac
    38521 agacctgcct atcattggaa tgggaggagt ggattcggct gaagctgccc tagaaatgta
    38581 tctggctggg gcatctgcta tcggagttgg aacagctaac tttaccaatc cttatgcctg
    38641 ccctgacatc atcgaaaatt taccaaaagt catggataaa tacggtatta gcagtctgga
    38701 agaactccgt caggaagtaa aagagtctct gaggtaaact gcaatcaatc tgttcttgat
    38761 tttttattag tttgtaatat gaatttagga gaattttggt acaataaaat aaataagaac
    38821 agaggaagaa ggttaatgaa gaaagtaaga tttatttttt tagctctgct atttttctta
    38881 gctagtccag agggtgcaat ggctagtgat ggtacttggc aaggaaaaca gtatctgaaa
    38941 gaagatggca gtcaagcagc gaatgagtgg gtttttgata ctcattatca atcttggttc
    39001 tatataaaag cagatgctaa ctatgctgaa aatgaatggc taaagcaagg tgacgactat
    39061 ttttacctca aatctggtgg ctatatggcc aaatcagaat gggtagaaga caagggagcc
    39121 ttttattatc ttgaccaaga tggaaagatg aaaagaaatg cttgggtagg aacttcctat
    39181 gttggtgcaa caggtgccaa agtaatagaa gactgggtct atgattctca atacgatgct
    39241 tggttttata tcaaagcaga tggacagcac gcagagaaag aatggctcca aattaaaggg
    39301 aaggattatt atttcaaatc cggtggttat ctactgacaa gtcagtggat taatcaagct
    39361 tatgtgaatg ctagtggtgt caaagtacag caaggttggc tttttgacaa acaataccaa
    39421 tcttggtttt acatcaaaga aaatggaaac tatgctgata aagaatggat tttcgagaat
    39481 ggtcactatt attatctaaa atccggtggc tacatggcag ccaatgaatg gatttgggat
    39541 aaggaatctt ggttttacct caagtttgat ggcaaaatgg ctgaaaaaga atgggtctac
    39601 gattctcata gtcaagcctg gtactacttc aaatccggtg gttacatgac agccaatgaa
    39661 tggatttggg ataaggaatc ttggttttat cttaaatctg atgggaaaat agctgaaaaa
    39721 gaatgggtct acgattctca tagtcaagct tggtactact tcaaatccgg tggttacatg
    39781 acagccaatg aatggatttg ggataaggaa tcttggtttt acctcaaatc tgatgggaaa
    39841 atagctgaaa aagaatgggt ctacgattat catagtcaag cctggtacta cttcaaatct
    39901 ggtggctaca tggcgaaaaa tgagacagta gatggttatc agcttggaag cgatggtaaa
    39961 tggcttggag gaaaagctac aaatgaaaat gctgcttact atcaagtagt gcctgttaca
    40021 gccaatgttt atgattcaga tggtgaaaag ctttcctata tatcgcaagg tagtgtcgta
    40081 tggctagata aggatagaaa aagtgatgac aagcgcttgg ctattactat ttctggtttg
    40141 tcaggctata tgaaaacaga agatttacaa gcgctagatg ctagtaagga ctttatccct
    40201 tattatgaga gtgatggcca ccgtttttat cactatgtgg ctcagaatgc tagtatccca
    40261 gtagcttctc atctttctga tatggaagta ggcaagaaat attattcggc agatggcctg
    40321 cattttgatg attttaagct tgagaatccc ttccttttca aagatttaac agaggctaca
    40381 aactacagtg ctgaagaatt ggataaggta tttagtttgc taaacattaa caatagcctt
    40441 ttggagaaca agggcgctac ttttaaggaa gccgaagaac attaccatat caatgctctt
    40501 tatctccttg cccatagtgc cctagaaagt aactggggaa gaagtaaaat tgccaaagat
    40561 aagaataatt tctttggcat tacagcctat gatacgaccc cttacctttc tgctaagaca
    40621 tttgatgatg tggataaggg aattttaggt gcaaccaagt ggattaagga aaattatatc
    40681 gataggggaa gaactttcct tggaaacaag gcttctggta tgaatgtgga atatgcttca
    40741 gacccttatt ggggcgaaaa aattgctagt gtgatgatga aaatcaatga gaagctaggt
    40801 ggcaaagatt agtactataa gtgaatatga tttgagtgaa tagtaagtta aaaatcctga
    40861 tttcaagtaa aatcaggatt ttttcatgga tgcaattttt ttggagtctg gtgtgacgcg
    40921 gagggtcttt tgtcctgtgt aagtgacaaa gccgggtttt ccaccagttg gtttattgag
    40981 ttttttgact tcaatcatat ctacctgcac cagattcgac aggcgccctt gagagaagta
    41041 ggcagctaac tctgctgcgt ctgtcttgac tgcatcagat gggtcaagat ttcctgagat
    41101 gacaacatgg cttccaggaa tgtccttagc atggaaccaa agttcctcct tgcgggccat
    41161 tttaaaggtc aattcctcat tttgaagatt gtttcgtccg acatagatga tggttttgcc
    41221 atcgcttgct agatattgtt ctagtttttt gcgtttctgg attttctccc gttgtcttct
    41281 gcggataaaa cctgtttgaa tcaattcttc acggatttca gcgatttctt ccagtccagc
    41341 ttggttgagg acggtttcta cactttccag atagagaata gtggctttgg tttcttcaat
    41401 caaatcagtc aagtatttga cagcttcttt gagtttctga taccgtttaa aatagcgttg
    41461 ggcattctgg ttgggagtca gagccttatc aagcgcaatc atgataggtt ggttggtata
    41521 gtagttgtct aggataacct ggtcttggtc gttaggcact tggtggagga aggttgtcag
    41581 caattctcct ttttgacgaa attcttcagc gttgtctgtc gccagtaact ctttttcctg
    41641 ttttttgagt ttgtgtcggt ttttctgaag ttcattttca acacgacgaa tcagttcact
    41701 ggcctgttgt ttgacgcggt cgcgctcagc cttattctta tagtaggtgt ccaacaaatc
    41761 agaaagattt gcaaaaggct ctcccgcctg atttgcaaaa ggaactggac tgaaggaagt
    41821 ctcagtcaag catggcttgg tttcttgatt gaaaaaattt cggaaagcgg aaagtttttc
    41881 actaaccagt atcctttcca attcatttgc cgtatcgcgt cccagacctt gaaagaggct
    41941 ttgaagattt tttgctgtta gttcttgggt ttgcaggatt tcaaagagct tttcatcctt
    42001 gatagtaaaa ggattgagag attctgtact tggcggagcg atataggtcg atcctggaag
    42061 taaggtgcgg tagctatttt gtgaaaaacc gacgtgtttg ataacttcga ggattttatg
    42121 actgctttta tcgaccagta gaatattact gtgtttcccc ataatttcga taatcaaggt
    42181 agcctggata tggtctccaa tctcgttttt attggaaact gtcatttcca caatacggtc
    42241 attttccact tgctcaatcg actcaatcag ggccccctgc aaatactttc tcaaaaccat
    42301 gataaaggta gaaggttggg ctggattttc aaaagtcgtt tgggtcagct gaatgcgtcc
    42361 aaaaactgga tgggcagaaa ggagcaggcg atggctttgg cgattgctgc ggatttgcaa
    42421 gaccaactct tgttcaaaag gctgattgat tttctggatg cgaccattca ctaattcgct
    42481 tcgcaattcc tcaactatgt ggtgtaaaaa aaatccgtca aatgacatcg ttctctcctt
    42541 gtgattgtat tccatagtat tatatcaaaa aggtagaata aaatcatgga aatgtggtat
    42601 aataaagcca agtaaagaga aacgagaagc acatgtatat tgaaatggta gatgaaactg
    42661 gtcaagtttc aaaagaaatg ttgcaacaaa cccaagaaat tttggaattt gcagcccaaa
    42721 aattaggaaa agaagacaag gagatggcag tcacttttgt gaccaatgag cgtagtcatg
    42781 aacttaatct ggagtaccgt gacaccgacc gtccgacaga tgtcatcagc cttgagtata
    42841 aaccagaatt ggaaattgcc tttgacgaag aggatttgct tgaaaatcca gaattggcag
    42901 agatgatgtc tgagtttgat gcctatattg gggaattgtt catctctatc gataaggctc
    42961 atgagcaggc cgaagaatat ggtcacagct ttgagcgtga gatgggcttc ttggcagtac
    43021 acggcttttt acatattaac ggctatgatc actatactcc ggaagaagaa gcggagatgt
    43081 tcggtttaca agaagaaatt ttgacagcct atggactcac aagacaataa acgaaaatgg
    43141 aaaaatcgtg acttgatatc cagtttagaa tttgctttga caggtatttt tactgctatc
    43201 aaggaagaac gcaatatgcg aaaacacgca gtgacggctc tagtggtcat ccttgcaggt
    43261 tttgtttttc aggtgtcacg aatcgaatgg ctctttctcc tattgagcat tttcttggta
    43321 gtagcctttg agattatcaa ctctgctatt gaaaatgtgg tggatttggc cagtcactat
    43381 cacttttcca tgctggctaa aaatgccaag gatatggcgg ctggcgcggt attagtggtt
    43441 tctctttttg cagccttaac aggcgcattg atttttctcc cacgaatctg ggatttatta
    43501 ttttaaacag taagaggaaa ttatgacttt taaatcaggc tttgtagcca ttttaggacg
    43561 tcccaatgtt gggaagtcaa cctttttaaa tcacgttatg gggcaaaaga ttgccatcat
    43621 gagtgacaag gcgcagacaa cgcgcaataa aatcatggga atttacacga ctgataagga
    43681 gcaaattgtc tttatcgaca caccagggat tcacaaacct aaaacagctc tcggagattt
    43741 catggttgag tctgcctaca gtacccttcg cgaagtggac actgttcttt tcatggtgcc
    43801 tgctgatgaa gcgcgtggta agggggacga tatgattatc gagcgtctca aggctgccaa
    43861 ggttcctgtg attttggtgg tgaataaaat cgataaggtt catccagacc agctcttgtc
    43921 tcagattgat gacttccgta atcaaatgga ctttaaggaa attgttccaa tctcagccct
    43981 tcagggaaat aacgtgtctc gtctagtgga tattttgagt gaaaatctgg atgaaggttt
    44041 ccaatatttc ccgtctgatc aaatcacaga ccatccagaa cgtttcttgg tttcagaaat
    44101 ggttcgtgag aaagtcttgc atctaactcg tgaagagatt ccgcattctg tagcagtagt
    44161 tgttgactct atgaaacgag acgaagagac agacaaggtt cacatccgtg caaccatcat
    44221 ggtcgagcgc gatagccaaa aagggattat catcggtaaa ggtggcgcta tgcttaagaa
    44281 aatcggtagc atggcccgtc gtgatatcga actcatgcta ggagacaagg tcttcctaga
    44341 aacctgggtc aaggtcaaga aaaactggcg cgataaaaag ctagatttgg ctgacttggg
    44401 ctataatgaa agagaatact aagtagaggt aggctcatgc ctgcttcttg tttttacaga
    44461 aggaggactt atgcctgaat tacctgaggt tgaaaccgtt tgtcgtagct tagaaaaatt
    44521 gattatagga aagaagattt cgagtataga aattcgctac cccaagatga ttaagacgga
    44581 tttggaagag tttcaaaggg aattgcctag tcagattatc gagtcaatgg gacgtcgtgg
    44641 aaaatatttg cttttctgcc tgacagacaa ggtcttgatt tcccatttgc ggatggaggg
    44701 caagtatttt tattatccag accaagtgcc tgaacgcaag catgcccatg ttttcttccg
    44761 gtttgaagat gggggcacgc ttgtttatga ggatgtacgc aagtttggaa ccatggaact
    44821 cttggtgcct gaccttttag acgcctactt tatttctaaa aaattaggtc ctgaaccaag
    44881 cgaacaagac tttgatttac aggtctttca agctgccctt gccaagtcca aaaagcctat
    44941 caaatcccat ctcctagacc agaccttggt agctggactt ggcaatatct atgtggatga
    45001 ggttctctgg cgagctcagg ttcatccagc tagaccttcc cagactttga cagcagaaga
    45061 agcgactgcc attcatgacc agaccattgc tgttttgggc caggctgttg aaaaaggcgg
    45121 ttccaccatt cggacctata ccaatgcctt tggggaagat ggaagcatgc aggattttca
    45181 tcaggtctat gataagactg gtcaagaatg tgtacgctgt ggtaccatca ttgagaaaat
    45241 tcaactaggc ggacgaggca cccacttttg tccaaactgt caaaggaggg actgatgaga
    45301 aaaatcatcg gaatcactgg gggaattgcc tctggtaagt caactgtgac aaattttcta
    45361 agacagcaag gctttcaagt agtggatgcc gacgcagtcg tccaccaact acagaaacct
    45421 ggtggtcgtc tgtttgaggc tctagtacag cactttgggc aagaaatcat tcttgaaaac
    45481 ggagaactca atcgccctct cctagctagt ctcatctttt caaatcctga agagcaaaaa
    45541 tggtctaagc aaattcaagg ggagattatc cgtgaggaac tggctacttt gagagaacag
    45601 ttggctcaga cagaagagat tttcttcatg gatattcccc tactttttga gcaggactac
    45661 agcgattggt ttgctgagac ttggttggtc tatgtggacc gagatgccca agtagaacgc
    45721 ttaatgaaaa gggaccagtt gtccaaggat gaagctgagt ctcgtctggc agcccagtgg
    45781 cctttagaaa aaaagaaaga tttggccagc caggttcttg ataataatgg caatcagaac
    45841 cagcttctta atcaagtgca tatccttctt gagggaggta ggcaagatga cagagattaa
    45901 ctggaaggat aatctgcgca ttgcctggtt tggtaatttt ctgacaggag ccagtatttc
    45961 tttggttgta ccctttatgc ccatcttcgt ggaaaatcta ggtgtaggga gtgagcaagt
    46021 cgctttttat gcaggcttag caatttctgt ctctgctatt tccgcggcgc tcttttctcc
    46081 tatttggggt attcttgctg acaaatacgg ccgaaaaccc atgatgattc gggcaggtct
    46141 tgctatgact atcactatgg gaggcttggc ctttgtccca aatatctatt ggttaatctt
    46201 tcttcgttta ctaaacggtg tatttgcagg ttttgttcct aatgcaacgg cactgatagc
    46261 cagtcaggtt ccaaaggaga aatcaggctc tgccttaggt actttgtcta caggcgtagt
    46321 tgcaggtact ctaactggtc cctttattgg tggctttatc gcagaattat ttggcattcg
    46381 tacagttttc ttactggttg gtagttttct atttttagct gctattttga ctatttgctt
    46441 tatcaaggaa gattttcaac cagtagccaa ggaaaaggct attccaacaa aggaattatt
    46501 tacctcggtt aaatatccct atcttttgct caatctcttt ttaaccagtt ttgtcatcca
    46561 attttcagct caatcgattg gccctatttt ggctctttat gtacgcgact tagggcagac
    46621 agagaatctt ctttttgtct ctggtttgat tgtgtccagt atgggctttt ccagcatgat
    46681 gagtgcagga gtcatgggca agctaggtga caaggtgggc aatcatcgtc tcttggttgt
    46741 cgcccagttt tattcagtca tcatctatct cctctgtgcc aatgcctcta gcccccttca
    46801 actaggactc tatcgtttcc tctttggatt gggaaccggt gccttgattc ccggggttaa
    46861 tgccctactc agcaaaatga ctcccaaagc cggcatttcg agggtctttg ccttcaatca
    46921 ggtattcttt tatctgggag gtgttgttgg tcccatggca ggttctgcag tagcaggtca
    46981 atttggctac catgctgtct tttatgcgac gagcctttgt gttgccttta gttgtctctt
    47041 taacctgatt caatttcgaa cattattaaa agtaaaggaa atctagtgcg agtaaaaatt
    47101 aatctcaaat gctcctcttg tggcagtatc aattacctaa ccagtaaaaa ttcaaaaacc
    47161 catccagaca agattgaggt tttaaagtat tgtcccaagg aaagaaaagt aaccctacat
    47221 cttgaatcta agtagatttt atggtaaaat aatagggatt ttaaggagtt tgatatgtat
    47281 aacctattat taaccatttt attagtatta tctgttgtga ttgtgattgc aattttcatg
    47341 caaccaacca aaaaccaatc cagcaatgta tttgatgcca gttcaggtga tttgtttgaa
    47401 cgcagtaaag ctcgcggttt tgaagctgta atgcagcgtt tgacagggat tttagtcttt
    47461 ttctggctag ccattgcctt agcattgacg gtattatcaa gtagataaga aaataatggg
    47521 caggactagg tctttgcctc tttttatttt taaaggatgt ttgagaaggt tttacagtaa
    47581 aagaaaatta aaaaatctag aaagaaaata tgaaagatag aataaaagaa tatttacaag
    47641 acaagggaaa ggtgactgtt aatgatttgg ctcaggcttt gggaaaagac agttccaagg
    47701 attttcgtga gttgattaaa accttgtcct taatggaaag aaagcaccaa attcgttttg
    47761 aagaagatgg tagtctgaca ttagaaatta agaaaaaaca tgagattacc ctcaagggga
    47821 tttttcatgc ccataaaaat ggctttggct ttgttagtct ggaaggcgag gaggacgacc
    47881 tttttgtagg gaaaaatgat gtcaactatg ctattgatgg tgataccgtc gaggtagtga
    47941 ttaagaaagt cgctgaccgc aataagggaa cagcagcaga agccaaaatt attgatatcc
    48001 tagaacacag tttgacaaca gttgtcgggc aaatcgttct ggatcaggaa aaacctaagt
    48061 atgctggcta tattcgttca aaaaatcaga aaatcagtca accgatttat gttaagaaac
    48121 cagccctaaa attagaagga acagaagttc tcaaggtctt tatcgataaa tacccaagca
    48181 agaaacatga tttctttgtc gcgagtgttc tcgatgtggt gggacactca acggatgtcg
    48241 gaattgatgt tcttgaggtt ttggaatcaa tggacattgt atccgagttt ccagaagctg
    48301 ttgttaagga agcagaaagt gtgcctgatg ctccgtctca aaaggatatg gaaggtcgtc
    48361 tggatctaag agatgaaatt acctttacca ttgacggtgc ggatgccaag gacttggacg
    48421 atgcagtgca tatcaaggct ctgaaaaatg gcaatctgga gcttggggtt cacatcgcag
    48481 atgtttctta ttatgtgacc gaggggtctg cccttgacaa ggaagccctt aaccgtgcga
    48541 cttctgttta cgtgacagac cgagtggtgc caatgcttcc agaacgacta tcaaatggca
    48601 tctgctctct caatccccaa gttgaccgcc tgacccagtc tgctattatg gagattgata
    48661 aacatggtcg tgtggtcaac tataccatta cacaaacagt tatcaagacc agttttcgta
    48721 tgacctatag cgatgtcaat gatatcctag ctggcgatga agaaaagaga aaaaaatatc
    48781 ataaaattgt accaagtatc gaactcatgg ccaagcttca tgaaacttta gaaaacatgc
    48841 gtgtgaaacg tggagctctc aattttgata ccaatgaagc gaagatttta gtggataaac
    48901 aaggtaagcc tgttgatatc gttcttcggc agcgtggtat tgccgagcgg atgattgagt
    48961 cttttatgtt gatggctaat gaaacagttg ccgaacattt cagcaagttg gatttgcctt
    49021 ttatctatcg aattcacgag gagcctaagg ctgaaaaggt tcagaagttt attgattatg
    49081 cttcgagttt tggcttgcgc atttatggga ctgccagtga gattagtcag gaggcacttc
    49141 aagacatcat gcgtgctgtt gagggagaat cttatgcaga tgtattgtcc atgatgcttc
    49201 ttcgctctat gcagcaggct cgttattcgg agcacaatca cggccactat ggactagctg
    49261 ctgactatta tactcacttt accagtccaa ttcgtcgtta tccagacctt cttgttcacc
    49321 gtatgattcg ggattacggc cgttctaagg aaatagcaga gcattttgaa caagtgattc
    49381 cagagattgc gacccagtct tccaaccgtg aacgtcgtgc catagaagct gagcgtgaag
    49441 tcgaagccat gaaaaaggct gagtatatgg aagaatacgt gggtgaagag tatgatgcag
    49501 ttgtatcaag tattgtcaaa ttcggtctct ttgtcgaatt gccaaacaca gttgaaggct
    49561 tgattcacat cactaatcta cctgaatttt atcatttcaa tgagcgtgat ttgactcttc
    49621 gtggagaaaa atcaggtatc actttccgag tgggtcagca gatccgtatc cgtgttgaaa
    49681 gagcggataa aatgactgga gagattgatt tttcattcgt acctagtgag tttgatgtga
    49741 ttgaaaaagg cttgaaacag tctagtcgta gtggcagagg gcgtggttca aatcgtcgtt
    49801 cggataagaa ggaagacaag agaaaatcag gacgctcaaa tgataagcgt aagcattcac
    49861 aaaaagacaa gaagaaaaaa ggaaagaaac ctttttacaa ggaagtagct aagaaaggag
    49921 ccaagcatgg caaagggcga gggaaaggtc gtcgcacaaa ataaaaaggc acgccacgac
    49981 tatacaatcg tagatacgct agaggcaggg atggtcctga ctggaactga aatcaagagt
    50041 gtacgagctg ctcgaattaa tctcaaggat ggctttgctc aagtgaaaaa tggagaagtt
    50101 tggctgagca atgttcatat cgcgccttac gaagagggca atatctggaa ccaggaacca
    50161 gaacgtcgtc gtaaactcct gctccataaa aggcaaattc aaaaattgga acaagagacc
    50221 aaagggacag gaatgacctt agttcccctt aaggtctata taaaagatgg ctacgctaag
    50281 cttcttttag gacttgccaa agggaagcat gactatgaca aacgggagtc tatcaaacgt
    50341 cgtgagcaaa atcgagatat cgcgcgtgtg atgaaagctg ttaatcagcg ataaaaagag
    50401 gaattgaaaa tggaaaaatt agttgcctat aaacgcatgc ctttgtggaa taaacaaaca
    50461 atgcctgaag ctgttcagca aaagcacaat acaaaagttg ggacttgggg gaaaattact
    50521 gtcttgaagg gagctctcaa gtttattgaa ttgacagaag aaggggaagt tctagctgaa
    50581 cacctctttg aagcaggggc agacaatcca atggcccaac ctcaagcctg gcaccgagtg
    50641 gaagctgcca cagatgatgt ggaatggtac ttggaatttt attgtaaacc tgaggattat
    50701 tttgctaaaa aatacaatac caatcctgtt cattcagagg tcctagaggt catggagaca
    50761 gtgaaacaag ggaaagcttt ggatttgggt tgtggtcagg ggcgtaattc tctttttcta
    50821 gcccagcaag attttgatgt gacggctgta gatcaaaatg gactagctct tgaaatcttg
    50881 caaagcattg tggagcagga agatttggac atgcctgttg gcctttacga tatcaattca
    50941 gctagcattg aacaagaata tgattttatc gtttcaacag ttgttctcat gtttctacaa
    51001 gcggaccgca ttccagctat tattcaaaat atgcaggaga aaaccagtgt tggtggttac
    51061 aaccttatcg tttgtgccat ggacacggag gattatcctt gctcggttaa cttcccattc
    51121 acctttaaag aaggagaact ggcagactat tacaaggatt gggaattggt taagtacaat
    51181 gaaaatccag gccatttgca tcgtcgcgat gagaatggca atcgtattca actacgcttt
    51241 gcgaccttac tagctaagaa aatcaagtaa acacacatga agattaggaa ttttcctgat
    51301 cttttttctt ttttacgaat gatatagaaa aggagggaat tcatgtttgt tgcgagagat
    51361 gctaggggag aattggtaaa tgtgttagag gataaacttg agaagcaagc atacacctgc
    51421 ccagcttgtg gaggccagct ccatttgcgt caaggaccaa gtgtacggac gcattttgcc
    51481 cataaatcct taaaagactg tgattttttc tttgaaaatg aaagtccaga acacctggcc
    51541 aataaggaat ccctctatca ctggttgaaa aaagagacaa aggttcaatt agagtacccg
    51601 ctttcagaac ttaaacagat tgcggatgta tttgtaaatg gcaatctagc tctagaagtt
    51661 cagtgtagtc ccttgcctca gaaagtcctt aaagagcgaa gtgagggcta tcgtagtcag
    51721 ggttaccaag tactgtggtt gctgggtcaa aaactgtggc tcaaggagcg tttgactcgt
    51781 ctacagcaag gttttcttta tttcagtcaa aacatgggct tttatgtttg ggaattagac
    51841 aaggaaaaac aagttttaag actcaaatac ctgatttacc aggatctccg cggtaaactc
    51901 cattatcaaa tcaaggaatt ttcctatggt caaggtagtt tattggaaat attgcgtctt
    51961 ccctataaga gacaaaaaat atctcatttt acagtttctg aggacaagga catctgtcgc
    52021 tatatccggc aacaacttta ttatcaaaat ctcttttgga tgaaagaaca agcagaagcc
    52081 tatcaaaagg gagaaaatat cctgacttat ggactgaaag aatggtatcc acaaattcga
    52141 ccaatagtgg gcaaattttt ccagattgaa caagacttga ctagctatta tcagcacttt
    52201 tatacctatt accaaaaaaa tcctcaaaat gattggcaaa agctttatcc accagccttt
    52261 tatcagcaat atttcttgaa aaatatggta gaatagaaag gatggaggaa tctaatggta
    52321 ttacaaagaa atgaaataaa tgaaaaagat acatgggatc tatcaacgat ctacccaact
    52381 gaccaggctt gggaagaagc cttaaaagat ttaacagaac aattggagac agtagcccag
    52441 tatgaaggcc atctcttgga tagtgcggat aacctactag aaatcactga attttctctt
    52501 gaaatggaac gccagatgga gaagctttac gtttatgctc atatgaagaa tgaccaggat
    52561 acacgtgaag ctaagtatca agagtactat gccaaggcca tgacactcta cagccagtta
    52621 gaccaagcct tttcattcta tgatcctgaa tttatggaga ttagcgaaaa gcagtatgct
    52681 gactttttag aagctcaacc aaagctgcag gtttatcaac actattttga caagctcttg
    52741 caaggcaagg atcacgttct ttcacaacgt gaagaagaat tattggctgg agctggagaa
    52801 atctttggtt cagcaagtga aaccttcgct atcttggaca atgcggatat tgtgttccct
    52861 tatgtcctag acgatgatgg taaagaagtt cagctatctc atgggactta cacacgtttg
    52921 atggagtcta aaaaacgtga ggttcgccgt ggtgcctatc aagctcttta tgcgacttac
    52981 gaacaattcc aacacaccta tgccaaaacc ttgcaaacca atgttaaggt gcaaaattac
    53041 cgtgctaaag ttcgtaacta caagagtgct cgtcatgcag ctctcgcagc gaattttgtt
    53101 ccagaaagtg tttatgacaa tttggtagca gcagttcgca agcatttgcc actcttacat
    53161 cgctatcttg agcttcgttc aaaaatcttg gggatttcag atctcaagat gtacgatgtc
    53221 tacacaccgc tttcatctgt tgaatacaat tttacctacc aagaagcctt gaaaaaagca
    53281 gaagatgctt tggcagtctt gggtgaggat tacttgagcc gtgtcaaacg tgccttcagc
    53341 gagcgttgga ttgatgttta cgaaaatcaa ggcaagcgtt caggtgccta ctctggtggt
    53401 tcttacgata ccaatgcctt tatgcttctc aactggcagg acaatctgga caatctcttt
    53461 actcttgttc atgaaacagg tcacagtatg cattcaagct atactcgtga aactcagcct
    53521 tatgtttacg gagattactc tatctttttg gctgagattg cctcaactac caatgaaaat
    53581 atcttgacgg agaaattatt ggaagaagtg gaagacgacg caacacgctt tgctattctc
    53641 aataacttcc tagatggttt ccgtggaaca gttttccgcc aaactcaatt tgctgagttt
    53701 gaacacgcca ttcaccaagc agatcaaaat ggggaggtct tgacaagcga tttcctaaat
    53761 aaactctacg cagacttgaa ccaagagtat tatggtttga gtaaggaaga caatcctgaa
    53821 atccaatacg agtgggctcg cattccacac ttctactata actactatgt atatcaatat
    53881 tcaactggct ttgcggccgc ctcagccttg gctgaaaaaa ttgtccatgg tagtcaagaa
    53941 gaccgtgacc gctatatcga ctacctcaag gcaggtaagt cggactatcc acttaatgtc
    54001 atgagaaaag ctggtgttga tatggagaag gaagactacc tcaacgatgc ctttgcagtc
    54061 tttgaacgcc gtttaaatga gtttgaagcc cttgttgaaa aattaggatt ggcataaaat
    54121 ggttgaatcg tatagtaaga atgctaacca taacatgcgt cgtcctgtcg tcaaagaaga
    54181 aattgtagac ttgatgcgtc agcgtcaaaa gcaggtcaca ggtttcttga aagaattgga
    54241 agactttgcc cgcaaggaaa atattcctat tattccccat gaaacggttg cttatttccg
    54301 ttttcttatg gaaaccatgc agcctaaaaa tattctggaa attgggacgg ctatcggttt
    54361 ttcagctctc ttgatggctg aacatgcgcc aaatgctaag attacaacta ttgatcgtaa
    54421 tccagaaatg attggttttg ccaaggaaaa ttttgcccag tttgacagtc gcaagcaaat
    54481 cactctccta gagggagatg cggtggatgt cttatctaca ctgacagagt cttatgattt
    54541 cgtctttatg gattctgcca agtctaaata catcgtcttt ctgccagaaa tcctcaaaca
    54601 tttggaagtt ggtggtgtgg ttgtcttgga tgatattttt caaggtggtg atgttgccaa
    54661 ggatattatg gaagtccgtc gtggtcagcg aaccatttat cgaggccttc aaaaattatt
    54721 tgatgcaacc ttagacaatc cagaactcac cgcaacatta gtgcctttag gagatggtat
    54781 tctcatgctt cgtaaaaatg tagcagatgt tcaactgtct gaaagcgaat gattttcaga
    54841 aaaatttaag aaaaaatagt aaaatagata gagtaacact tatctcaaag gagtagacat
    54901 gaagaaaaaa ttattggcag gtgccatcac actattatca gtagcaactt tagcagcttg
    54961 ttcgaaaggg tcagaaggag cagaccttat cagcatgaaa ggggatgtca tcacagaaca
    55021 tcaattttat gagcaagtga aaaacaaccc ttcagcccaa caagtcttgt taaatatgac
    55081 catccaaaaa gtttttgaaa aacaatatgg ctcagagctt gatgataaag aggttgatga
    55141 tactattgcc gaagaaaaaa aacaatatgg cgaaaactac caacgtgtct tgtcacaagc
    55201 aggtatgact cttgaaacac gtaaagctca aattcgtaca agtaaattag ttgagttggc
    55261 agttaagaag gtagcagaag ctgaattgac agatgaagcc tataagaaag cctttgatga
    55321 gtacactcca gatgtaacgg ctcaaatcat ccgtcttaat aatgaagata aggccaaaga
    55381 agttctcgaa aaagccaagg cagaaggtgc tgattttgct caattagcca aagataattc
    55441 aactgatgaa aaaacaaaag aaaatggtgg agaaattacc tttgattctg cttcaacaga
    55501 agtacctgag caagtcaaaa aagccgcttt cgctttagat gtggatggtg tttctgatgt
    55561 gattacagca actggcacac aagcctacag tagccaatat tacattgtaa aactcactaa
    55621 gaaaacagaa aaatcatcta atattgatga ctacaaagaa aaattaaaaa ctgttatctt
    55681 gactcaaaaa caaaatgatt caacatttgt tcaaagcatt atcggaaaag aattgcaagc
    55741 agccaatatc aaggttaagg accaagcctt ccaaaatatc tttacccaat atatcggtgg
    55801 tggagattca agctcaagca gtagtacatc aaacgaatag tccaaatcaa tgagtcaggg
    55861 aaaaaactcg acttcaggaa aaaatgaagc aaacattccc acaataaaac gcatagtaca
    55921 aggtttgtac tgccccccaa aaaagttaga caattaattt atccgaagga tttagttctg
    55981 tattgcacag agctaagtcc ttttagtttt atcttaattc tcttattgtt gtaataatca
    56041 atatagtcta taatggcttg ttccaattga ttaagtgatt taaatgtttg ctcatagcca
    56101 taaaacattt cggattttaa aatgccaaag aaagattcca tcctaccgtt gtcttggctg
    56161 tttcctttgc gtgacataga tgcttgaatt cccttactct ctaggaagcg atgataagaa
    56221 tcgtgttggt attgccagcc ttggtcacta tggagaatcg tattctcgta gtgcttctct
    56281 ttgaatgcct gttccaacat taacgatcaa tcaatttaat catgtaccta agattagaat
    56341 tgtttatccc aaatttattt gaaagcttct ctaagctata tccttgtttt ctaagttcat
    56401 agatctgaac tttatcatca taagttaatt tcataataaa aacaccccaa aagttagatt
    56461 ttttctgtct aacttttggg gtgtagttca tgtacacctg atatgatgcg ttttataatt
    56521 ttaaagactt tttgaccagc ctcatttttt taacttgata ctcagtgaaa agcaaagatt
    56581 aaactaggaa gctagctgta ggctgctcaa agaacagctt tgaggttgca gataaaactt
    56641 gtgaggtaac caacatatat aatgtgaagc tgacgtggtt tgaatagatt ttagaagggt
    56701 atgagtctgg aagttttaat ggataatgca agattccata gaatgggtaa gctagagttc
    56761 ttatgtgaag agtttgggca taaactttta ccttttcctc cctactcatc ttagtataga
    56821 aaagtgaatc taaaatagta cataactgct tctaaaacat tcttataaat tgatttaaat
    56881 tctcaaatca tattattcag ttcttatttc attttgctct acaatcctgt tgagaagaca
    56941 cgtgttcata tcaaaaaggt attggcaagt tgcaatacct ttttacaagg ttcttttgtc
    57001 ttatttttgt ttcaactgac tatatctcct atggttctag ttcagaaggc taggctataa
    57061 ttatgattga taagaagtat cattccaagt attgagagtg aatgtttcaa aatcatgggt
    57121 ttctataatg gtcaggctgg catttgctag accgccatct ttacgaagaa gtggttcttt
    57181 atagcctagg agagtacgaa gactggcagt aagattggcg ccgtgtccga caattagaat
    57241 acgctcagct ggactatctt ttaatgattt gataaattgg atggtccgct gagttgtact
    57301 atagagggat tcggctccga acattcgagt gtcaaattga gcaagatttg aacgaaaagc
    57361 ctggatttgt tgcgggtaaa tagcttccag ggttgcaatt ttcaaacctt ctaacttccc
    57421 aagttgccat tcacggagat taggaacgat ttctaaagaa cagggggtat ggagttgact
    57481 ttggataatc tcagcagatt tgaccgctcg aggtaaatca cttgaataaa tctgatcaaa
    57541 aggaatttcc ttgagatact ggccaagtcg ttttagggtt tcaatggatt caggaagaag
    57601 aggagaatca ccgctagcac cttgaaaacg accttcttgg ttccagaggg tacgaccgtg
    57661 gcggacaaag tagagtttca ttacttgatg tcctccaaaa tatctacaaa gtctgccttt
    57721 acaaagctag ccaagtcttg tggcgcgacg ataatgctgt gtccgacttc gcctgcagag
    57781 acaatcattc gatccaaatc tagagcaatt ttatcgataa aaatgggata attgtgtttc
    57841 tgacgaattc cgacaggatt attggctcca tgaatgtaac cagttgtttt ttctaagtcc
    57901 ttttgtagaa tcatgctcac ttttttattg ccagaaattt tagctagttt cttttcagac
    57961 aagtgctgag tgatagggac aattccgata atcggtccgg tcttgtctcc caaaagcgcc
    58021 aaggttttga aaatctgatc tcgttcataa ccttgaggaa gctctccttc tagggcattg
    58081 atttgaatcc cctgatgagg gatggctgct ttagatagga tttgttccac caatgttttt
    58141 ttgattttaa ctttttttgc cattatttat atttatcctc caattgactc atccaaatac
    58201 caagccagat tcccagcgca aagaagaagg cgatgatgac ataaccgaca agtgaaagtc
    58261 ctgtgtattg gatactttca gcgtttcctg catttggaat taagatcaaa agggtacttg
    58321 ataggacgat accgatgatg aaatgataga cgcgtgagtg gtagttgttt aaggcataat
    58381 ccatcaattt tgaaaaaacg atgagagttg cacctgcacc aattccaatc ggaaagaagg
    58441 ttcccaagag atcaaaagtt ttaaaaccag tcaacatagg agcatagagt cccaaaatca
    58501 aaagtaaatt cgatgggctg aggccaggaa ccaagacgcc aagggccaat agtgcgcctg
    58561 ctaggacgaa gttaagaaag ctggcgctta aggttccaac gacaaaattt aaggcatata
    58621 gtcctaatcc agaaatgata aaggttgtcc ataaccaagc taaatcaatc ttgtctcggt
    58681 cagattctcg agttgattct ttgaggaggc taggaactgt accgataata gctcccgcaa
    58741 agctccataa tacaaagacc tgataatttt caagcaggta ttcaatcggg taggaaaata
    58801 agccgattcc cagaagcata ccgatggcaa ctggaataaa gtacaaaaca ttttctttaa
    58861 ggtctttaaa gggatgggcc agaaagccaa tcattcgttc atagattcct aagattgctg
    58921 ctagaacccc tccggaaatt cccggtagga taaatccaag agcaattaca atccctttaa
    58981 taacgcgtgc taaccatgag agcatatatt tcctccaact atttctattt caaaaaatcc
    59041 ttactatatt gtatcacaat cagacacaaa aagaaaaagc aaatgataaa caaatgcttt
    59101 taaggtttta aaaaaagctt tcgaaaggtt tcttctttat tttttaaggg agagataacg
    59161 ttgatatcta aatcgtggtc aaagccggca atttttcctt tagatgtgta ttggtgaata
    59221 tcataatcta aatcagtttt aggactgctc tccaaaaatc ctgagtctga gccgtaggac
    59281 ggaatccaaa cagaggtaaa cttgcctgta tcaatactgt gttcttccat gaagtagaca
    59341 ccaacgtaga tgccgatgtt tttagcacct agtgatgcta gttttgctcg aaagttttcg
    59401 acaccttcgt tcatattaga catagttttg tcttccacgt caagccaata gtaactaggg
    59461 ctgtaaggag aggcagcatt gtagaaaact tcggcagcct tttccatttc ttggacactt
    59521 tttccagcta cataagcgta gacagcaact gggacattcc gcttttgaag ttcagtgata
    59581 tgactcttat aggccttgtc tattccattg ataaatgaag catcattttc ttttgtcgtt
    59641 tgagcaccac tgtgaacacg aacaatagca cctgaaatat tttgtgagag ggcatcgtag
    59701 ttgatttcct caggacgctg ccagccagag aggtcaataa tcggtttgtc taagtgtttc
    59761 aaagcctgtg cttcaatctg tgctatattg gattttgttt taaacgattg gctgtcatta
    59821 agtgggcgat tgatgattaa aatgaacatc ataatcccaa aaaaactaaa taaaataagt
    59881 ggatgaattt gttttctcat atcttataat tctaccctaa aaatcaaaaa aaatcaaaaa
    59941 aatgggttaa ggaagagact ttagagcatt ttttcattca agagtgcgga atgatttgaa
    60001 atatggtata ataaaaggga atttctacag aaaagagaag attatgtcaa attttgccat
    60061 tattttagca gcgggtaaag ggactcgcat gaaatctgat ttgccaaaag ttttgcacaa
    60121 ggttgcgggt atttctatgt tggaacatgt tttccgtagt gtgggagcta tccaacctga
    60181 aaagacagta acagttgtag gacacaaggc agaattggtt gaggaggtct tggctggaca
    60241 gacagaattt gtgactcaat ctgaacagtt gggaactggt catgcagtta tgatgacaga
    60301 gcctatctta gaaggtttgt caggacacac cttggtcatt gcaggagata ctcctttaat
    60361 cactggtgaa agcttgaaaa acttgattga tttccatatc aatcataaaa atgtggccac
    60421 tatcttgact gctgaaacgg ataatccttt tggctatgga cgaattgttc gtaatgacaa
    60481 tgctgaggtt cttcgtattg ttgagcagaa ggatgctaca gattttgaaa agcaaatcaa
    60541 ggaaatcaac actggaacat acgtctttga caacgagcgt ttgtttgagg ctttgaaaaa
    60601 tatcaatacc aataacgctc aaggcgaata ctatattaca gacgtcattg gtattttccg
    60661 tgaaactggt gaaaaagttg gcgcttatac tttgaaagat tttgatgaaa gtcttggggt
    60721 aaatgaccgt gtggcgcttg cgacagctga gtcagttatg cgtcgtcgca tcaatcataa
    60781 acacatggtc aacggtgtta gctttgtcaa tccagaagca acttatatcg atattgatgt
    60841 tgagattgct tcggaagttc aaatcgaagc caatgttacc ttgaaagggc aaacgaaaat
    60901 tggtgctgag actgttttga caaacggtac ttatgtagtg gacagcacta tcggagcagg
    60961 agcggtcatt accaattcta tgattgagga aagtagtgtt gcagacggtg tgacagtcgg
    61021 tccttatgct cacattcgtc caaattcaag tctgggtgcc caagttcata ttggtaactt
    61081 tgttgaggtg aaaggatctt caatcggtga gaataccaag gctggtcatt tgacttatat
    61141 cggaagctgt gaagtgggaa gcaacgttaa tttcggtgct ggaactatta cagtcaacta
    61201 tgacggcaaa aacaaataca agacagtcat tggagacaat gtctttgttg gttcaaattc
    61261 aaccattatt gcaccagtag aacttggtga caattccctc gttggtgctg gttcaactat
    61321 tactaaagac gtgccagcag atgctattgc tattggtcgc ggtcgtcaga tcaataaaga
    61381 cgaatatgca acacgtcttc ctcatcatcc taagaaccag taggagccta tcatggagtt
    61441 tgaagaaaaa acgcttagcc gaaaagaaat ctatcaagga ccaatattta aactggtcca
    61501 agatcaggtt gaattaccag aaggcaaggg aactgcccaa cgggatttga ttttccacaa
    61561 tggggctgtc tgtgttttag cagtaacgga tgaacaaaaa cttatcttgg tcaagcagta
    61621 ccgcaaagct atcgaggctg tctcttacga aattccagcc ggaaaattgg aagtaggaga
    61681 aaacacagcc cctgtggcag ctgcccttcg tgaattagag gaagaaacag cctatacagg
    61741 gaaattagaa ctcttgtacg atttttattc agctattggc ttttgtaatg agaagttaaa
    61801 actatattta gcaagcgatt tgacaaaagt ggaaaatccg cgtccgcagg atgaggatga
    61861 aaccttggaa gtccttgaag tgagcttaga agaagcgaaa gaattaatcc aatcaggtca
    61921 tatttgtgat gccaagacaa ttatggctgt tcagtattgg gagttgcaga aaaaatagag
    61981 gaggtcagta tgggtaaatc tttattaacg gatgaaatga ttgaaagagc taatagaggc
    62041 gaaaaaattt caggtcctcc tttgctagat gataatgagg aaactaagat tttaccaacc
    62101 tcttcttccc gttttggtta tgccaatcct aaggatcatg gttttagcca ggaaaccttg
    62161 aagattcagg tcgaaccatc tattcataaa agccgtcgta ttgaaaatac caagagaaat
    62221 gtcttcaatt ctaagttgaa taaaatctta tttgcggtca tctttctctt gattttgctt
    62281 gttttagcaa tgaaactttt gtaatagaaa aggaattgaa atgaaaatag gaattattgc
    62341 tgctatgcca gaagaactgg cttatctggt ccagcattta gataatgccc aggagcaagt
    62401 tgttttgggg aatacctatc atacaggaac cattgcttct catgaagtcg ttcttgtaga
    62461 aagtggaatt ggtaaggtca tgtctgctat gagtgtggcg attttggctg atcatttcca
    62521 ggtggatgcc cttattaata cgggttcagc tggggcagta gcagaaggta tcgctgttgg
    62581 ggatgtcgtg attgctgaca aattagccta tcatgacgtg gatgtcacag cttttggcta
    62641 tgcttatgga caaatggcgc aacaaccgct ttatttcgaa tcagacaaaa cctttgttgc
    62701 tcaaatccaa gagagtttat ctcaattgga ccaaaactgg catcttggtt tgattgctac
    62761 aggagatagt tttgttgcag gaaatgacaa gatagaagcg attaagtccc atttcccaga
    62821 agttttagcc gtggagatgg agggggcagc tattgctcaa gcagcgcatg ccctcaatct
    62881 cccagtctta gtcatccgag ctatgagtga caatgccaac catgaagcaa acatcttttt
    62941 tgatgagttt attatcgaag ctggacgtcg ctctgcccaa gtcttgttgg cctttttgaa
    63001 ggctttagat taagcggaaa tttgacagtt tttctagctt atgataagat ttaagtaaag
    63061 aaaagctaga aaacgtttca gaggatatta tgagtattga aatgaccgtc agtgagattg
    63121 cagaggtctt aggattatct cgccaagcaa tcaataaccg tgtcaaagaa ttaccagaag
    63181 aagacacaga taaaaatgac aaaggggtaa cagttgttac cagaagtggc ttgattaagc
    63241 tagaagaaat ctataaaaaa acgatttttg aagatgagcc tgtcagtgaa gatgtcaaac
    63301 aacgtgaact gatggagatt ctagtggatg agaagaatgc agaaattctt cgtctttatg
    63361 aacaattaaa agccaaggat cgtcagttat cagaaaaaga cgagcagatg cgtatcaaag
    63421 accgtcagat tgctgagaaa gacaaacaat tagatcagca acaacaattg acccttcaag
    63481 ccatgaagga tcaagaaaat cttaagctag agctggacca agcaaaagaa gaagtccaat
    63541 ccactaagaa aggctttttt gctcgtttat ttggaggata atcaaggagc tgtttaggtt
    63601 aaatgctaac ctgatggctt cttttgtttg tgaatagtat agttgattag aacagagaca
    63661 gtagaggaga ggtacagaat ggaacgatta gaagattaca ttgcttttga cttagaattt
    63721 aatcagcacg aaggacaaac acacttgatt caagtatcgg cagtgcgttt tagagatggt
    63781 cgggaaatcg atgcctatga ttcctatgtt cataccagcg tccctctaaa aagctttatc
    63841 aatggtttga ccgggattac agctgagacc ttaaaagatg ctcctccagt tgagaaagtc
    63901 ttagaagaat tccaagagtt tgtgggttct ttgctgatga taggctacaa tgctgctaaa
    63961 agtgatttac ctattttagc agagcatggt ttagactata gccaacagta caaggtggat
    64021 ttgtatgatg aagcttttga acgtcggagt tcagatttac atggtattgc caatctcaaa
    64081 ttgcaaactg ttgcctcatt tcttggattt caaggtcagt ctcataatag tttagaggat
    64141 gctcggatga cggcgcgtgt ttacgaatcc ttcttagagt cggatcaagc tagggaattg
    64201 ttagagacag aaagtagctt atcaaacaat ccttttggtg gcttggactt gtctcaatta
    64261 tttgactagg agtgcctatg aaacctgaaa aacctaaaaa attgggtctt aaacagattt
    64321 acctcaatct tgataaaatc ctctttctat ttttcttgat ttttatgata gtggagtatt
    64381 tgtgggtacc attcaattca tggttggcta gcttcttatt agatcagaca ggttatcttt
    64441 ttatttccta taacaatgtc ttagccatcc ttactcattc tccattgatt agtctagctt
    64501 ttttagcctt gattgtaatt aaccttctgg ttgcttattt tcaaatagga ctcctcttta
    64561 ttggtgctcg tcatctcctc tataatgaaa agcgaaggct aattgagtat atccgcaagg
    64621 ttttccatga aagttttgga tttatgaaaa agctaacttg cgctaaagcc ttgtttatct
    64681 ttttctatat agctatgctt tttcctttta tacggaaaat gttgaagatt tattatctta
    64741 ataaaatcgt cattccagag tttatccaag cttatttaga agataaatat tggatgtggt
    64801 ggctgagcat cctacttcta tctcttatct ttctctatgt ctctgtcaga ttgatgtttg
    64861 cccttccgaa gattgtatat gatcagctga ctgttcgaga agcagtgatg tttagcttgg
    64921 agaaaaccaa gaagagagtt actttttatg cttggaattt attttacatc ttgctcaaag
    64981 cacatttatt attttatctt cctttgattc ctttattatt ggctcaaact ttggtagatg
    65041 atatcactca gagagagtct ctgattcttg gtattttgaa ttttgtcgtg attaaaaatc
    65101 tctattatat ggctctgact tattttttgg ttaaatttgt ttcatttttg acaggaaagg
    65161 agctggatat gcttcctagg agagaaaaag atcacatcgt gcgatggggt gtcatgactt
    65221 gtgccagtct tttctttgcc ttagaaggtt atatttatct ggaggctccc atggttcatc
    65281 tacctcaact tatttctcac cgaggggttt ccaatgcaaa tgggattcaa aatacagtag
    65341 agtccttgga aactacagca caactcaaac cagacttggt ggagacggac gtgcaggaaa
    65401 caaaagatgg gcagtttgtc atgatgcatg atgctaactt gaaaaattta gcaggtatca
    65461 ataaaagtcc tcaagactta aacttggagg agcttaaagg gattgatatt tttgaaaatg
    65521 gctaccagac taaaatttca agctttgaag attatctcag tcgagccaac gaacttggtc
    65581 aaaaattact aattgaaatt aaaaccagta aaaaagatag tccagacatg atgaaccgct
    65641 ttttagcccg ttatgctgca aagctcaaga tttatggaca tcaaatccag tctttagact
    65701 accatgttgt cgaaaaagta agacagtatg atgccgaact gccagtttat ttcatcatgc
    65761 cctacaattc tgtctttcct aaaacaagag cgacaggata tactatggag tactcaacct
    65821 tggatgaata ttttgtaagc aaactatgga caacggatca gaaactttat gtctggactg
    65881 tcaatgattc agaagctatc agcaaatctc ttcacttagg agtagatgga gtgattacag
    65941 atgatttgga aaaagttcag cgggaaatag aagtagccca agaagatcca gaatatacgg
    66001 atttgctctt gaaaaaagca ttggaattct ttgaatttta gtaataaaaa agaggaacgg
    66061 ttgttcctcc catgataggt aagtattctt gtgaatgctt gcttttttgt ggttgcaatc
    66121 cgtttacgag aattgtttgt attgttcttg tttcaattta ctttatagtg ctttgaagtt
    66181 ggaatgctac actataactt ctaaaatata gtaaaatgaa ccaaaaatag tacacaatga
    66241 ggtataatct t
//
LOCUS       DAVKBC010000006        64440 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVKBC010000006 DAVKBC010000000
VERSION     DAVKBC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.006"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            9..1355
                     /gene="celB"
                     /locus_tag="VWX64_000451"
     CDS             9..1355
                     /gene="celB"
                     /locus_tag="VWX64_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU9189995.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANSATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            1736..1912
                     /locus_tag="VWX64_000452"
     CDS             1736..1912
                     /locus_tag="VWX64_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9189996.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFRSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            2313..4526
                     /locus_tag="VWX64_000453"
     CDS             2313..4526
                     /locus_tag="VWX64_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU9189997.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDSLWLLNHYHYQDSCKNAEGGLTLSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVQTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDVSNI
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(4748..5224)
                     /locus_tag="VWX64_000454"
     CDS             complement(4748..5224)
                     /locus_tag="VWX64_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU9189998.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            5447..8650
                     /locus_tag="VWX64_000455"
                     /pseudo
     CDS             5447..8650
                     /locus_tag="VWX64_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            9031..9407
                     /gene="tnpA"
                     /locus_tag="VWX64_000456"
                     /pseudo
     CDS             9031..9407
                     /gene="tnpA"
                     /locus_tag="VWX64_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(9795..10424)
                     /locus_tag="VWX64_000457"
     CDS             complement(9795..10424)
                     /locus_tag="VWX64_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU9189999.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDKSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPSSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(10434..11435)
                     /locus_tag="VWX64_000458"
     CDS             complement(10434..11435)
                     /locus_tag="VWX64_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU9190000.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIQPNMLDMDSLFQGISHFHFSGITVAIGQEVRTILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(11466..12107)
                     /locus_tag="VWX64_000459"
     CDS             complement(11466..12107)
                     /locus_tag="VWX64_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU9190001.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(12126..12941)
                     /locus_tag="VWX64_000460"
     CDS             complement(12126..12941)
                     /locus_tag="VWX64_000460"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU9190002.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            13213..13647
                     /locus_tag="VWX64_000461"
     CDS             13213..13647
                     /locus_tag="VWX64_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9190003.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            13659..14849
                     /locus_tag="VWX64_000462"
     CDS             13659..14849
                     /locus_tag="VWX64_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU9190004.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINEDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGMTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            14859..15350
                     /locus_tag="VWX64_000463"
     CDS             14859..15350
                     /locus_tag="VWX64_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9190005.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKVALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            15365..16144
                     /locus_tag="VWX64_000464"
     CDS             15365..16144
                     /locus_tag="VWX64_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9190006.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            16131..16949
                     /locus_tag="VWX64_000465"
     CDS             16131..16949
                     /locus_tag="VWX64_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9190007.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            16949..17242
                     /locus_tag="VWX64_000466"
     CDS             16949..17242
                     /locus_tag="VWX64_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9190008.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            17264..19165
                     /locus_tag="VWX64_000467"
     CDS             17264..19165
                     /locus_tag="VWX64_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU9190009.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            19225..20226
                     /locus_tag="VWX64_000468"
     CDS             19225..20226
                     /locus_tag="VWX64_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9190010.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(20336..20671)
                     /locus_tag="VWX64_000469"
     CDS             complement(20336..20671)
                     /locus_tag="VWX64_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190011.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(20682..20924)
                     /locus_tag="VWX64_000470"
     CDS             complement(20682..20924)
                     /locus_tag="VWX64_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190012.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(20935..21477)
                     /locus_tag="VWX64_000471"
     CDS             complement(20935..21477)
                     /locus_tag="VWX64_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU9190013.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(21493..21687)
                     /locus_tag="VWX64_000472"
     CDS             complement(21493..21687)
                     /locus_tag="VWX64_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9190014.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            21853..22803
                     /gene="rsmH"
                     /locus_tag="VWX64_000473"
     CDS             21853..22803
                     /gene="rsmH"
                     /locus_tag="VWX64_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU9190015.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            22815..23132
                     /gene="ftsL"
                     /locus_tag="VWX64_000474"
     CDS             22815..23132
                     /gene="ftsL"
                     /locus_tag="VWX64_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU9190016.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            23136..25388
                     /gene="pbpX"
                     /locus_tag="VWX64_000475"
     CDS             23136..25388
                     /gene="pbpX"
                     /locus_tag="VWX64_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU9190017.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            25390..26370
                     /locus_tag="VWX64_000476"
     CDS             25390..26370
                     /locus_tag="VWX64_000476"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU9190018.1"
                     /translation="MFIFISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLFTSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKIFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            26979..29084
                     /locus_tag="VWX64_000477"
     CDS             26979..29084
                     /locus_tag="VWX64_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9190019.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTCGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQVAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(29380..29862)
                     /locus_tag="VWX64_000478"
     CDS             complement(29380..29862)
                     /locus_tag="VWX64_000478"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU9190020.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(29957..31441)
                     /locus_tag="VWX64_000479"
     CDS             complement(29957..31441)
                     /locus_tag="VWX64_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU9190021.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYTGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKISRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            31593..33200
                     /locus_tag="VWX64_000480"
     CDS             31593..33200
                     /locus_tag="VWX64_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU9190022.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDELIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPMQEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            33359..33532
                     /locus_tag="VWX64_000481"
     CDS             33359..33532
                     /locus_tag="VWX64_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU9190023.1"
                     /translation="MNIKKRVLGAGLTFASALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(33525..34053)
                     /locus_tag="VWX64_000482"
                     /pseudo
     CDS             complement(33525..34053)
                     /locus_tag="VWX64_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            34231..35437
                     /locus_tag="VWX64_000483"
                     /pseudo
     CDS             34231..35437
                     /locus_tag="VWX64_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            35439..36169
                     /locus_tag="VWX64_000484"
                     /pseudo
     CDS             35439..36169
                     /locus_tag="VWX64_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
     gene            36178..36870
                     /gene="cpsC"
                     /locus_tag="VWX64_000485"
     CDS             36178..36870
                     /gene="cpsC"
                     /locus_tag="VWX64_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU9190024.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVA
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLGKLK"
     gene            36880..37297
                     /locus_tag="VWX64_000486"
                     /pseudo
     CDS             36880..37297
                     /locus_tag="VWX64_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase"
     gene            complement(37366..37821)
                     /locus_tag="VWX64_000487"
                     /pseudo
     CDS             complement(37366..37821)
                     /locus_tag="VWX64_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
     gene            37845..38261
                     /locus_tag="VWX64_000488"
                     /pseudo
     CDS             37845..38261
                     /locus_tag="VWX64_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
     gene            38439..39623
                     /locus_tag="VWX64_000489"
     CDS             38439..39623
                     /locus_tag="VWX64_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU9190025.1"
                     /translation="MKIAIAGSGYVGLSLAVLLAQHHEVKVIDVIKDKVESINNRKSP
                     IKDEAIEKYLVEKELNLEASLDPAHVYKDVEYAIIATPTNYDVDLNQFDTSSVEAAIK
                     TCMEYNDTCTIVIKSTIPEGYTKEVREKFNTDRIIFSPEFLRESKALYDNLYPSRIVV
                     GTDLDDSELTKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVAYFN
                     EIDTYSEVKGLNPKTIIDIVCYDPRIGSYYNNPSFGYGGYCLPKDTKQLKASFRDVPE
                     NLITAVVQSNKTRKDYIAGAILAKQPSVVGIYRLIMKSDSDNFRSSAVKGVMERLDNY
                     GKEIVIYEPTIECDTFMGYRVIKSLDEFKNISDIVVANRMHDDLRDIQEKLYTRDLFG
                     RE"
     gene            39639..40892
                     /locus_tag="VWX64_000490"
     CDS             39639..40892
                     /locus_tag="VWX64_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000287926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9190026.1"
                     /translation="MYTFILMLLDFFQNHDFHFFMLFFVFILIRWAVIYFHAVRYKSY
                     SCSVSDEKLFSSVIIPVVDEPLNLFESVLNRISRHKPSEIIVVINGPKNERLVKLCHD
                     FNEKLENNMTPIQCYYTPVPGKRNAIRVGLEHVDSQSDITVLVDSDTVWTPRTLSELL
                     KPFVCDKKIGGVTTRQKILDPERNLVTMFANLLEEIRAEGTMKAMSVTGKVGCLPGRT
                     IAFRTEILRECIHEFMNETFMGFHKEVSDDRSLTNLTLKKGYKTVMQDTSVVYTDAPT
                     SWKKFIRQQLRWAEGSQYNNLKMTPWMIRNAPLMFFIYFTDMILPMLLISFGVNIFLL
                     KILNITTIVYTASWWEIILYVLLGMIFSFGGRNFKAMSRMKWYYVFLIPVFIIVLSII
                     MCPIRLLGLMRCSDDLGWGTRNLTE"
     gene            41190..42110
                     /gene="galU"
                     /locus_tag="VWX64_000491"
     CDS             41190..42110
                     /gene="galU"
                     /locus_tag="VWX64_000491"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU9190027.1"
                     /translation="MKKVKKAVIPAAGLGTRFLPATKALAKEMLPIVDRPTIHFVIEE
                     ALRSGIEDILVVTGKSKRSIEDYFDSTFELEYSLRKQGKMELLKSVNESTDIKVHFVR
                     QSSPRGLGDAVLQAKSFVGDDPFVVMLGDDLMDITDSTAVPLTRQLMDDYNATQASTI
                     AVMPVRYEDVSSYGVISPRLESSNGLYSVDAFVEKPKPEEAPSNLAIIGRYLLTPEIF
                     SILETQKPGAGNEIQLTDAIDTLNKTQSVFAREFVGKRYDVGDKFNFMKTSIDYALQH
                     PQIKESLKNYVIALGKQLEKLDDCSSSGHL"
     gene            42107..43324
                     /locus_tag="VWX64_000492"
     CDS             42107..43324
                     /locus_tag="VWX64_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU9190028.1"
                     /translation="MNCIESYQKWLNVPDLPAYLKDELLSMDDKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLVESKGETAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMLPADADALTDYIRAIDNPFAVALADLEEAKSTGLIEVIGETLDSAYLEEVKSVNI
                     NQDLIDQYGRDMKIVYTPLHGTGEMLARRALAQAGFESVQVVEAQAKPAPDFSTVASP
                     NPESQAAFALAEELGRQVDADVLVATDPDADRLGVEIRQADGSYWNLSGNQIGALIAK
                     YILEAHKQAGTLPKNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEEG"
     gene            complement(43251..43808)
                     /locus_tag="VWX64_000493"
     CDS             complement(43251..43808)
                     /locus_tag="VWX64_000493"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9190029.1"
                     /translation="MIKCLFPNAQIVLDRFHIIQHLSREMMTTRIVIMKNFDKQSLPY
                     RAMKNHWRIFQKDSRKLSDKAFYSRTFRQTLTPREIVNKTLAFSDELHYYDDLYQLLL
                     FHLQEKNADHFFDLLTEAFPQLNQAFRTALSTLVRYRKYVTNTIQMPYSNSKLEAINK
                     LISLLQTQTCRYGYVFLQILEFSQR"
     gene            43808..44896
                     /locus_tag="VWX64_000494"
                     /pseudo
     CDS             43808..44896
                     /locus_tag="VWX64_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein"
     gene            45197..50500
                     /locus_tag="VWX64_000495"
     CDS             45197..50500
                     /locus_tag="VWX64_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU9190030.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQERVKTEDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HYPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EVGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTSLVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTTTDWPDNNKSKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(50666..52825)
                     /locus_tag="VWX64_000496"
     CDS             complement(50666..52825)
                     /locus_tag="VWX64_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU9190031.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(52822..53418)
                     /gene="recU"
                     /locus_tag="VWX64_000497"
     CDS             complement(52822..53418)
                     /gene="recU"
                     /locus_tag="VWX64_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU9190032.1"
                     /translation="MVNYPHKVSPQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLLAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            53484..54011
                     /locus_tag="VWX64_000498"
     CDS             53484..54011
                     /locus_tag="VWX64_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU9190033.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            54081..54410
                     /gene="gpsB"
                     /locus_tag="VWX64_000499"
     CDS             54081..54410
                     /gene="gpsB"
                     /locus_tag="VWX64_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU9190034.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            54431..54811
                     /gene="rnpB"
                     /locus_tag="VWX64_000500"
     ncRNA           54431..54811
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VWX64_000500"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            54896..56053
                     /locus_tag="VWX64_000501"
     CDS             54896..56053
                     /locus_tag="VWX64_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU9190035.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            56066..57460
                     /gene="mapZ"
                     /locus_tag="VWX64_000502"
     CDS             56066..57460
                     /gene="mapZ"
                     /locus_tag="VWX64_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU9190036.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSLSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            57536..58960
                     /gene="gndA"
                     /locus_tag="VWX64_000503"
     CDS             57536..58960
                     /gene="gndA"
                     /locus_tag="VWX64_000503"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU9190037.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            58972..59661
                     /locus_tag="VWX64_000504"
     CDS             58972..59661
                     /locus_tag="VWX64_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9190038.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            59760..60782
                     /gene="cbpC"
                     /locus_tag="VWX64_000505"
     CDS             59760..60782
                     /gene="cbpC"
                     /locus_tag="VWX64_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU9190039.1"
                     /translation="MKLLKKMMQVALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYSLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGSTWYYLDAENGDMKIGWTKVNGKWYYLNSSGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            60801..61799
                     /gene="cbpJ"
                     /locus_tag="VWX64_000506"
     CDS             60801..61799
                     /gene="cbpJ"
                     /locus_tag="VWX64_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEU9190040.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGMRLEGFPNS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDLTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(61917..63149)
                     /locus_tag="VWX64_000507"
     CDS             complement(61917..63149)
                     /locus_tag="VWX64_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9190041.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQILALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(63192..64154)
                     /locus_tag="VWX64_000508"
     CDS             complement(63192..64154)
                     /locus_tag="VWX64_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU9190042.1"
                     /translation="MTSSTEFGNFVSNLSFQHGIAGLLFPLNKLYPPELDSKILSIIK
                     KAVTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANVTAKKLIENYDTL
                     EEIDFALGKSGVLLSLIKYYQFTNDNTLKIFIHNSIGEIYHYFLQRDTAKESILDYSF
                     AHGYCGIAYALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKG
                     ISGIILYLCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLM
                     KKIQQVILACSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
BASE COUNT        19969 a        11181 c        14234 g        19056 t
ORIGIN      
        1 gtctatttat ggatcaacaa aacgggttgt ttggttttct tgaaaaccat gttatgggac
       61 caatgggcaa acttgctcag tttaaagtag tacgtgctat cacggctgca ggtatggctg
      121 ctgtaccatt tactattgta ggatcaatgt ttttggtatt cagtattttg ccacaagctt
      181 tctcattttg gccaattgtg gcagatattt tctctgcttc atttgataaa ttcacatcac
      241 tttacatggt tgcaaactct gcgactatgg gttctctatc tctttatttc gttctatcac
      301 ttgcatatga attgacaaaa atttatgcag aggaagaaga actcaatatg aatcctctta
      361 atggtgcctt gcttgccttg atggcttttg tcatgacagt accgcaaatc atttttgatg
      421 gtggaatgat gaagactgtg acaagtctaa aagaaggtgc agtaattgca gatggatggg
      481 caatgggaaa tggagtcgca cgttttggga caacagggat ttttaccgca atcattatgg
      541 caattgtgac tgttcttatt tatcgtatgt gtgttaaaca taattgggtt attaaaatgc
      601 ctgaagctgt tccagaagga gtttctcgtg gatttaccgc tttggttccg ggatttgttg
      661 ttgcatttgt tgttatcttt atcaacggtc ttcttgtagc aatgggaaca gatattttta
      721 aagtcattgc aattccattt ggttttgtat ccaatctgac taattcgtgg attggtttaa
      781 tgattattta tctattgact caactacttt ggattgtagg tatccacggt gcgaacattg
      841 tttttgcatt tgttagtcca attgctcttg ctaacatggc tgaaaatgct gctggcgggc
      901 acttcgctgt tgcaggtgaa ttttctaata tgtttgtaat tgcaggtggt tctggtgcaa
      961 ctttaggact atgtttatat attgcttttg cctctaaatc tgaacagctt aaagcaatag
     1021 gacgagcatc tgtagttccg gccttattta atattaatga accattaatt tttggattac
     1081 ctattatcta taatccagcc ttagctatac catttatttt agcaccaatg gttactgcta
     1141 ctatttatta cgtagcgaat tctctaaact ttattaagcc aattatcgca caggttccat
     1201 ggccaactcc agtagggatt ggagctttct tagggacagc agatcttcga gctgtattag
     1261 ttgctctagt atgtgcattt gcagcattcc tagtctatct tccattcatc cgtgtatatg
     1321 atcaaaaatt ggtgaaagaa gagcaaggta tctaataagt aaaaaagtat actcgatgat
     1381 agaatccata tagtttaaat aatgagcgtt aacattagca gtgaagaggt ctttttaaga
     1441 tattcttctc tgctttttca tattttttcg ctatgtaggg tatgaagcaa aatagaaagt
     1501 agttcgaata gttgataaac agggaattgc tgttatttaa aaaaaaacaa taaagtaaag
     1561 tatgttatcg tagaatacga tacaatagta aaaaagcaaa aagaatgcgt tttatatttg
     1621 ggtttgaggt ttataaaata ggataagcat gctgaaaact tagatatgac aaacaaaata
     1681 aaatttttaa aagctacata gaaacatggt ataatgtatc taaaggaggt agcatatgtc
     1741 cttagatata gataaagaaa agatgacaat catgggaata gcttttgaaa accgatccgt
     1801 ttttaggagt gtttggtatg ctttaagtac aaatatgatt gaaggatggc gacctacggt
     1861 tagtgatgtt gaaaaattac gagatgaagc tcttgctctg gggatgactt aatgaagcgc
     1921 aactgttatg agtcttatga ctatgttgat ccggataatt tatataccga tccgggttct
     1981 tcagttctaa gaaataagca ggaaggaaaa aagcacgcga gcttgaatat cgtatgattg
     2041 ctagtaagag tttgaaatta tttatcaatc ctatcttagt taatagttta aaagtagttt
     2101 gtttcacaac tgcataagct tagaaaagtt gaaaagtgat aactctttaa taaactcttg
     2161 gtttgttaaa agatattttg tccactacat tttttcaatt gactattatt tgtcatagat
     2221 ataacagata gaacattgca ttcagaataa tgaaaaacgc atcaaaaatg gtgcgttctg
     2281 tttttatgct accataaaag gaggaaaaca aattgaaaat ttttaaggga gagttttatc
     2341 gaatctctgt attaacagac aagctagtaa ggttagaata ctctcgaact ggaaattttg
     2401 aggatagaac gacacaactt atctataata gagattttgg ccaagtttcg ttagattata
     2461 tcgagacatc aaatgtacta gatattatga cggactattt tcatctgcac tttaataaag
     2521 gagaatttaa cgccgaaaat ttatttatag aattaaaagg aaattttgcc gtatatggta
     2581 gtcgctggta ttttggtgaa tctattgaaa cgttaaaagg aacagctcgg actctggata
     2641 aggcagatgg agcaatctcg ttagaagatg gaattattag ccgaaatggt atagccttat
     2701 tggatgattc tcaaggattt atttgggatg aacaatctgg ttatattgag agagaaaatc
     2761 aaattgacct gtatttcttt gcctatgggc atgattatag aggagcaatc agagactttt
     2821 accatttgac tggttcaaca cccttgttgc caagatatgc tttaggcaat tggtggagta
     2881 gatattggcc ttatacgtcg gatgaatact tggatttaat agacagattt gaaacagaga
     2941 aaattccatt atctatcggt gtgttagata tggattggca tataactgac attccagctc
     3001 gttttggaag tggctggaca ggatatagtt ggaatagaaa cttaatacca aatccagaac
     3061 agttattgca acaacttcat gatagaaagt taaaactctc cttaaatgtc catcctgctg
     3121 atgggatacg ggcttatgaa gaagcttatc ctcaaatcgc aaaacggttg gggttaaatg
     3181 tagaactaga agaacctgct atttttgatt tttttaatcc ctcttttagg gaagcctact
     3241 ttaaagatgt tcattatgag ctagaaaagc agggagtaga tttttggtgg attgactggc
     3301 aacaagggac acaaggtatg ctagattcac tttggctttt aaaccattat cactatcagg
     3361 atagttgtaa aaatgcagaa ggtggtttga ctttatcaag atatgcaggt cctggtagtc
     3421 accgctaccc tgttggtttt tcaggggata ctattattag ttggaattcc ttaagatttc
     3481 aaccctattt tacagcgaca gcatctaata tcggttatag ttggtggagt catgatatcg
     3541 gtggacatat gttgggggat tatgacgaag agctacaaac tagatggcta cagtttggtg
     3601 tttttagtcc gattactcga ttacatagtt ctagaagtcc ttttaatagt aaagaacctt
     3661 ggtttttttc agaaacaaca tctaagatta tgaagaaata ccttcgtttg agacatcaga
     3721 tgattcccta tctatatacc atgaatgtac agacacatga ggaaggtgcc ccattaatca
     3781 gtccaatcta ttatttctat ccagagaatg atgagagcta taatgttcca aaccaatact
     3841 tttttggaac agaactgatg gtggctccca ttgtagaaaa gatggatttg acattccaat
     3901 ctgcaaaagt agatgtatgg ttccctgaag gtgaatggta tgacttcttt tcagagaaaa
     3961 aatacacagg tggtgtgaag ttaagtgttt atagggacgt ttcgaatatt cctgtgtttg
     4021 caaaaagtgg tgcaatcatt cccttggttg gttctgagat aggtatgggt gttgatttac
     4081 ctgaggttgt agattggtat gtattcccag gcaaacaaca ttcttttgaa atgcttgaag
     4141 atcaaaatgg tcaaagatat aaaacaagat tatcaatcga ttgggaaatg ggaatggtag
     4201 agttagcatt acaaggagat tctagtatcg ttccaagcaa tagaaaacat agaattcatt
     4261 ttaaaggaac gaatgtgtct ataattgaat tgccaaataa gaatgataca gctaaatttg
     4321 aatggaaaga taataaaagg acatctttaa atgacgaagt ttttagacta ctaaagacag
     4381 cttctcttcc atatgaatta aaagatagat tgttaaatca attcatcaat gcgaaaaact
     4441 ctcatgactt aatgaatatc ttgcatcatc aggataagga attgagaggg cgtttgttgg
     4501 aaatgatatt tactagccaa aactaattga tataattaga aagtcatttg tttagtgtat
     4561 atgaagattc tgtatggtat tcgttatcac tggtcacatt gaaaatgtga aataagcacc
     4621 tacaacatag actttacaac acttcatgtt tcatatcatg gggtgttttt ctatttaagt
     4681 caaagccaat caaaaaattt cactattcat caggttaaag gaaacctaat catagtgaga
     4741 ttgtgaatta tagtagagtt tgtatcgcct cttcaatttg ttttgggtct gtttttgaag
     4801 aaaagcgttc aaagacttgc ccatcacgac caatgagaaa cttagcgaaa ttccattcga
     4861 ttcgttttcc tagtgggcca gatttatggt cttttaacca gacatagaga gggtctgctt
     4921 ccttaccgtt gaccttaatc ttggcaaaac gtgggaaggt ggtttgaaaa tgtaggctac
     4981 agaaggcgtt gatttcctct gcgctgccgg gtgcttgtcc cataaactga ttgcaaggga
     5041 aatccaatat ttcgaagccc tgatcttgat agcgttcata gagttcttga agtccctggt
     5101 actggggcgt taaaccacat ccagtagcag tgttgacaat caagagaact ttgccacgat
     5161 agctatccaa gggagttgct tggttgtttt ggttcaaaac ggaaaaatca taaagtgaag
     5221 tcatgagggc ctcttttctt tttctacatt gtaacagttt ttactttttt cgtcgagtcg
     5281 gatggaagat attgttgaag aataagcctt caatatgata gaaatcgttt acaaataact
     5341 ttaaaaatgg tatgatttaa ttaaatcggt ttactttgtt gctataaatc tctaatttga
     5401 gatttagttc ctattgattt tacaatatgt ttattggagt gtatacatgc aaacaaaaac
     5461 aaagaagctc attgtgagtt tgtcttcact tgttttatca ggatttttat taaaccatta
     5521 tatgacagtt ggagcggaag aaacgactac gaataccatt cagcaaagcc agaaggaagt
     5581 tcagtatcag caaagggata caaaaaattt agttgaaaat ggtgattttg gtcagacgga
     5641 ggacggaagc agtccgtgga caggaagcaa agctcagggg tggtcagctt gggtagacca
     5701 gaagaatagt tctgcagatg cctcaactcg agtcattgag gctaagggtg gggctatcac
     5761 tatctcaagc catgagaaat taagggcagc ggttcaccgt atggttccta ttgaagctaa
     5821 gaaatagtat aaactgcgtt tcaagattaa aacagataat aaagtcggga ttgccaaggt
     5881 tcgtatcatt gaggaaagtg gtaaggacaa gcgattgtgg aattctgcaa cgacgtcagg
     5941 aacaaaggac tggcagacca ttgaagcaga ctatagcccg actttagatg ttgataaaat
     6001 caagctggag ttattctatg aaacaggaac tgggactgtt tcctttaagg atattgagct
     6061 ggtagaggta gcagaccagc cttctgagga ttctcaaaca gataaacagc ttgaggaaaa
     6121 gattgattta ccaattggaa aaaaacatgt tttttctctt gcggactata cttataaggt
     6181 agaaagtcct gacgttgctt cagtcaaaaa tggaatttta gaacctctta aggaagggac
     6241 aaccaatgtc attgtcagta aagatggcaa ggaagtgaaa aagattcctt tgaagattct
     6301 agcctctgtt aaggatgcat acacagaccg tttggatgac tggaatggca tcatcgctgg
     6361 gaatcaatac tatgattcta aaaatgaaca gatggccaaa ttaaaccagg aattggaagg
     6421 aaaggtagct gatagcctat ctagtatttc aagtcaggcg gaccgcacct atttgtggga
     6481 aaaattttca aattataaaa tgtctgcaaa tctgactgcc acttatcgga aattggagga
     6541 gatggccaag caagtgacca atccttcttc tcgttattat caagatgaaa ctgtcgttcg
     6601 aacagtcagg gattccatgg aatggatgca taaacatgtc tacaatagtg aaaagagcat
     6661 tgttgggaac tggtgggatt atgaaatcgg tacacctcgt gccatcaaca ataccttgtc
     6721 tctgatgaaa gaatacttct ctgatgagga aattaaaaaa tatacagatg tgattgaaaa
     6781 atttgtacca gatcccgaac atttccgaaa gacgactgat aacccattca aggctctagg
     6841 tggaaactta gttgatatgg gaagggtaaa agtaatagct ggtttactgc gtaaggatga
     6901 tcaagaaatt tcttctacca ttcgctcgat tgagcaagtg ttcaagttgg tagagcaagg
     6961 tgaaggtttt tatcaagatg gatcctatat cgaccacacc aatgttgcct atacgggtgc
     7021 ttatgggaat gttttgattg atggcctgtc tcaactgttg ccagtcattc aaaagaccaa
     7081 gaatccaatc gataaagata aaatgcaaac catgtaccac tggattgata aatcgtttgc
     7141 tcctttgctg gtgaatggag agctgatgga tatgagtcgt ggacgctcga tcagtcgtgc
     7201 aaatagcgag gggcacgtgg ccgcagtaga agtactaaga gggattcacc gaatagcgga
     7261 tatgtctgaa ggagaaacca aacaacgttt gcagagtctt gtgaagacca ttgttcaatc
     7321 ggatagttat tatgatgtct ttaagaattt gaagacttat aaggatatca gtttgatgca
     7381 atccttgtta agtgatgcag gagtcgcaag tgttccaaga acaagttacc tatctgcctt
     7441 taacaagatg gataaaacag ccatgtacaa tgcagagaaa gggtttggat ttggcttgtc
     7501 actcttttcc agtcgtacct tgaattacga acacatgaac aaggaaaata aacgtggttg
     7561 gtatacgagt gatgggatgt tctatcttta caatggcgat ttgagtcact atagcgatgg
     7621 ctactggcca acagttaatc catataagat gcctggtaca acagagacgg atgctaagag
     7681 agcggatagc gatacaggta aagttttacc gtctgctttc gttggaacga gcaaactaga
     7741 tgatgccaat gcgacagcaa ccatggattt caccaactgg aatcaaacat tgactgctca
     7801 taagagctgg tttatgctaa aggataagat tgccttttta ggaagcaata tccaaaacac
     7861 ttcaacagat actgctgcaa ctacaatcga ccagagaaaa ctggaatcaa gtaatccata
     7921 taaagtctat gtcaatgata aagaagcctc ccttacagaa caagaaaagg attatcctga
     7981 aacccaaagt gtctttttag aatcgtccga ttcgaaaaag aatattggtt actttttctt
     8041 taagaagagt tcaatcagta tgagtaaggc tttgcaaaag ggagcctgga aggatatcaa
     8101 tgaaggacag tcagacaagg aagttgaaaa tgaatttctt acgattagtc aggctcataa
     8161 gcaaaatgga gattcttatg gctatatgct cattcctaac gtgggtcgtg ccaccttcaa
     8221 tcaaatgata aaagagttag aaagtagcct catcgaaaat aacgaaaccc ttcagtctgt
     8281 ttatgatgcc aaacaaggag tttggggcat tgtgaaatat gatgattctg tctctactat
     8341 ttccaaccaa ttccaagttt tgaaacgtgg agtctatacc attcgaaaag aaggggatga
     8401 atataagatt gcctactata atcctgaaac ccaggaatca gctccagatc aggaagtctt
     8461 taaaaagcta gagcaagcag ctcagccaca agtacagaat tcaaaagaaa aggaaaaatc
     8521 tgaagaggaa aagaaccatt cggatcaaaa gaatctccct cagacaggag aaggtcagtc
     8581 aatcttggca agtctagggt tcttgctact tggggcgttt tatttattcc gtagaggaaa
     8641 gaacaactaa tttgttcatc atctagatga attacatgaa actgtggaaa atagaaaaaa
     8701 tccgaagaag gccaaatatc ttcggatttt tcttttaaaa agggataagt tgatacttat
     8761 ccttttttac ttcattatgt gactatagcg ttttgaaact agaataggac gtcataactg
     8821 ctaaaagatt tctataaatt catttgattt tcctaatcaa tttgttcgta tcctatttca
     8881 ctccactata ttagtccgtc tcgctccgtg aggtgcgaga caaaacaacc acccgctatg
     8941 cgggtgcgcg tcgaagatta taccaaaaaa actccaaacg cgatacaata aaggtgttca
     9001 atccaattgt aaagcgaaag gagaaaaaat atggcacaaa agactcatag tttatcatac
     9061 acaaagtgga tgtgttctat catattgtgt tcacccctaa gtatagacga aaagtcatct
     9121 ataatcaata tagaagtagt ttaggcgaaa tatttcatcg cttgtgtagt tataaaggtg
     9181 ttgaaatgat cgagggtcac ttaatgccag accatgtaca catgttagtc agtattccac
     9241 taaggctaag tgtttcaagt tttatgggtt atttaaaagg caaaagtgca ctcatgatgt
     9301 ttgacaaaca cgccaatctc aagtacaagt ttgggaatcg gcatttttgg gcggaaggtt
     9361 attatgtaag tacagtaggg cttaataaag ccacaattaa gaaatatagt caagattaaa
     9421 gaaattatcc agtggatgat ttcttcacga gtatgaaaat ttgagaacga gtaaagcatg
     9481 atatatagta aaatgaaata agaataggac aaaatcgatc aggacagtca aatcgatttc
     9541 taacaatgtt ttagaagcag aggtgtacta ttccagtttc aatctactat agcactagat
     9601 aaattgagtg taaaagaata tgaggatccc tttagggata gtggtaagta ataccaaagt
     9661 ctcttaaaga ggcaagtgac gagtcaagag caataaggct tgaacaacgt gaaagccagc
     9721 gtctttaggc gctggctgat gatttgggct tatagctctg agataaacca cccgttagac
     9781 aggtggttat gattttatct gagtgtaaca tactgttggg caatctcgct gatgcggtca
     9841 aagttgcctt gggaagcgag tttattgagt tcgccaccaa ttccaacggc gtctgcacca
     9901 gcagcgaacc attgagggat gttgtttaga ccgactcctc cggttaccat tacggaaact
     9961 tgtgggatcg gtgccttgac tgcagagata tatgctggac tgagagtact acttgggaag
    10021 agtttgatga tttcactacc ggcttcaagt gcagtcgtga tctctgtgag ggtaatacag
    10081 cctggaatgt acggtgtgct gtagagattg cacattttcg cagtttcagc atggaaagat
    10141 ggagaaacaa cgtaatttgc tccggctaga atggcatctc tagcagttac ggcatcaagc
    10201 acagtacctg caccgataca aacactctta tcgtcctgat acaagtctac aagttccttg
    10261 atgatttgtc ctgcatactg attggtatag gcgatttcaa tagctttgat accgcccttg
    10321 atacaagcaa tcgaggcttg cagtccttct tcctttgtat ttccccgaat gacagcgaca
    10381 attttctgtt tttttagttc aataatcgta tctgatttgg tcatgtaatt ctcctaacga
    10441 atgatatctt gtgcatttgc cagtaaattt tcaatactag ttgcggaagt ggagagatgg
    10501 tctcctggaa gagtgcattt gagagttgcg ctcgcaactg caaagtcaat ggtagttttt
    10561 agggaggaat gatggagtag ttggtaaagg gcaccagata taaaggcatc cccgctacca
    10621 attcgttgat agactgcagt ttttagttgg acagactctt caaatagttc ttccagagca
    10681 taggcttgat agacattttt gtcttgctca tcactagagc ggagggtatg gaaaatggcc
    10741 ttgaaaccat aggcttcttt taaaagtcgc atgcgatttt ccacctcttc taggctagca
    10801 ctgtctcttg gaaacatctc tagattttgg tcatcaatca tgagaggatc aataccgaag
    10861 caatagtcag taaaacgtgc aaacttagaa aattcatact tggcttctag gactgaaatc
    10921 atctttgttc tcagattgag atccattgaa acgacaattc ctcggcgctt ggcttcttcc
    10981 aagagtagga gaaggatcgt acggacctct tgaccgatag ctacggtgat tccactaaaa
    11041 tgaaaatggc taatcccctg aaagagagaa tccatatcta gcatgtttgg ctgaatctgg
    11101 ctgatactcg tatgcttacg atcgtagaaa acttcacttt gacgacaacc aaagccgttc
    11161 tccaaatagt agaggccgat tcgatcgcca agccgacaga ttgaactggt atcgatttgg
    11221 tgctgtttca agaatgtgag aaaacgatct ccaatctcgt tggcagggag tgcggtaaag
    11281 actttcgttg agatacccag ggcttgcaaa ttacaagcga tgttaatttc tgatccgcca
    11341 aaataagtcg aactggcaac atgatcgccg atactggtgg catctaatgg tgagattcga
    11401 attaatggtt cgccaaacag taatattttc gtcatccatt agttcctttc tggtttagaa
    11461 tagctttact tggctaatac ttctttcaaa taagcagcga cttcatcatc ttggcagttt
    11521 tcaaagaagt attcttggaa gtatttgcca gagatggtgt ctttgaggaa gtcttggtcg
    11581 attgttttaa ggatggtcat caaatcattg tgggtgattt gtttcacctc gtttaagata
    11641 cgagcgttgc gttgttcagg gattacacgt tctcttgggt agccaccgcc catttcttca
    11701 gcaaataagc gttcaaacat caatttgagg gtcagttctg ccccccagcc aaatcctttg
    11761 gcataaggga tagacaaggc gttaccacca ttgatttgag aataaaggta agcgtcagtt
    11821 gggtccactg ctagaccaca gacaacacca gggaagctgt ttaaagcaag catagcccct
    11881 acacccgtac cacagccggt aacaacaaag tcaactgcct ttgtatttaa aaggatggca
    11941 gccattagtc cgttctgcac ataagttaat tgactttctc cttcttctcc acgcatacca
    12001 tagttaaata attggtagcc ttttttatct gtcgcttctt ttagactatc gtaaataatg
    12061 tgattcttgc tagcttgact attttcattg attaatgcga ttttcataag atcttctttc
    12121 tatttttact caggttgttt tccgatgtag gctaagatac cgccatctac atataggatg
    12181 tggccattga caaaattgct ggcatcacta gcgagaaaga cagcagggcc catcaaatct
    12241 tcaggatttc cccaacgtgc agcaggtgtt tttgcaatga tgaactggtc aaatgggtgg
    12301 cgagaaccat cttcttgcaa ttcacgaaga ggtgctgttt gaggagtggc aatataaccc
    12361 ggtccaattc cgttacattg gatattggct ccaccgtatt cagacgcaat gttgcgggtc
    12421 aacattttca agcccccttt agcagcagca taagcgctaa ctgtttcacg tcccagttcg
    12481 ctcatcatcg aacaaatatt gataatcttt ccatgccctt tctttatcat agaaggaata
    12541 actgcctttg aaacgataaa tggtgcgttt aagtcaatat cgatgacctt acggaaatca
    12601 gcggcgctca tttcgcacat tggaactcgg cggataatac cagcgttatt aacgaggatg
    12661 tcaatgacac caacctcttg ttcgatttgc ttgaccatgg cttggatacc gtcctcgtct
    12721 gtcacgtcac agacatatcc atgggcttcg atgccaactt cacgataagc ttcaatccct
    12781 ttattgacca gatcttgatt gatatcgtta aagacaatag tagcgccggc ttcagcgtag
    12841 gatttggcaa tagcaaatcc aattccataa gaagcgccgg tgatgagagc aatttttcct
    12901 tttaaagaaa actgctcaat tgagaatgat gtatttgtca tttgatactt cctttcaaat
    12961 ttgttaagac ttctctataa ccaaattata ttctagtaaa ccggttttgt caataaataa
    13021 atatttttat ttataaaaag atttgttttc ctaaaaaaac ggaagatttt gaaatttctg
    13081 tctattaaaa tggttaaaaa gataatgaaa gcgctaatat ttttttaaaa aaactattga
    13141 caagataaaa ataaaggatt acaatgggga atataaagta aaccggtaaa cctaaacaag
    13201 aaaggagaaa agatgaaaat tgtacttgta gggcatggac attttgctac agggatttat
    13261 agttctttac aattgattgc aggcaatcaa gaaaatgtgg aggcgattga ctttgtggaa
    13321 ggaatgtcag cagatgaact caagcaaaaa atcttacttg caatttcaaa tgaagaagaa
    13381 gttttaatcc taagtgatct cttgggagga tcgccattca aggtttcttc taccataatg
    13441 ggagaaaatc cagccaaaac aatgaatgtt ctctcgggtt tgaacttagc catgttaatg
    13501 gaagcagtct ttgctagaat ggctcatagc tttgatgaag ttgttaataa atcagtagtg
    13561 gcggcccagg gcggagtcgt aaatggtaaa gaattgtttt caacggatgc agaggaagag
    13621 gaagaagatt tcgaatcggg tatttaaagg gtaaaagaat gataaaaaag gttacgattg
    13681 aaaaaataaa atcgcctgag cgcttcttag aagtaccact tctgacgaaa gaagaagtcg
    13741 gccaggcaat cgataaggtt attcggcagt tagaactcaa ccttgactat ttcaaggaag
    13801 atttcccgac accagctacc tttgataatg tctatccaat catggataac acggaatgga
    13861 ccaatggttt ctggacagga gaactgtggt tggcttatga atacagtcaa caggatgcat
    13921 ttaaaaacat cgctcataaa aatgttcttt ctttcctgga tcgtgtcaat aagagagtag
    13981 aattggctca ccatgatctc ggcttcttgt acacaccgtc ttgtatggct gaatataaga
    14041 taaatgaaga tggagaggct agagaagcag ccttgaaagc tgcagataag ttgattgaac
    14101 gctatcaaga aaaaggtggt tttattcaag cttggggaga cttgggcaag aaagagcatt
    14161 accgtttgat tatcgattgc ttgctcaata tccaactctt attctttgct tatcaagaaa
    14221 caggcgatca aaaatactac gatattgcag aaagccattt ctatgcttca gctaataatg
    14281 taatccgtga tgacgcttcg tccttccaca ccttctattt tgatcctgag acaggtcaac
    14341 cctttaaagg tgtaacgaga caagggtata gtgatgattc atgctgggca cgtggtcagt
    14401 catggggagt ctatggtatt cctttgactt atcgtcactt aaaagacgag tcctgctttg
    14461 acttgtttaa gggtatgacc aattatttct tgaatcgtct gccaaaagat catgtgtcct
    14521 attgggattt gatttttaat gatggtagtg atcaatcacg agattcttca gcaacagcta
    14581 tcgccgtctg tgggattcat gaaatgctaa aacatctccc agaggtggat gctgacaaag
    14641 atatttataa acatgctatg catgccatgc ttcgttcctt gatcgaacat tatgcaaatg
    14701 atcaatttac ccctggtggg acaagtctcc tccacggtgt gtactcatgg cattcaggta
    14761 aaggagtgga tgaaggcaat atctggggtg actactatta cctagaagcc cttatccgtt
    14821 tctacaaaga ctggaaccta tattggtaga ggagaaatat gacaatgcca aatattatta
    14881 tgacccgtat cgatgaacgg ttgattcatg gacaaggaca actttgggta aaatacctag
    14941 gttgtaatac ggtcattgtt gccaatgacg aagtaagcac ggacaagatg caacaaactc
    15001 tgatgaaaac agttgtgcca gactcagttg ccatgcgttt cttccctttg caaaaggtga
    15061 ttgatatcat tcacaaggct aatcctgctc aaacgatctt tatcgttgta aaggatgtga
    15121 aggatgcttt aaccttggta gaaggtggtg tccctatcaa agaaatcaat attgggaaca
    15181 ttcacaatgc tactggtaaa gagcaagtga cacgctccat cttcctgggt gaagaggaca
    15241 aggtggccct caaggaattg agccaaactc atcaagtaac atttaatacg aaaacaactc
    15301 caacaggaaa tgatggagct gttcaagtca acattatgga ctatatttaa aagaggagat
    15361 cgttatgtcg attaatgtat ttcaagcgat tttaattgga ttatggacag ctttctgttt
    15421 tagtggaatg ctgttaggaa tttacaccaa tagatgtatt gttctgtcat ttggtgtcgg
    15481 aattattcta ggtgatctgc ctactgctct tgcaatggga gctattggtg aattggctta
    15541 tatgggattc ggtgttggtg ctggaggtac tgttccacca aacccaatcg gacctggtat
    15601 ctttggtacc ttgatggcta tcactagtgc tggtaaagtc agtccagaag cggctcttgc
    15661 cctctctact ccgattgctg tggcgattca attcttacaa actttcgcct acactgtacg
    15721 tgctggtgcg cctgaaacag cgatgaagca cttgaaaaac cataatttga agaaatttaa
    15781 gttcactcta aatgcaacaa tttggttgtt tgcctttatt ggatttacct tgggttgctt
    15841 gggtgccctt tcaatggata ccttgttgaa actcgtagac tacattccac cggtattgct
    15901 tacaggtttg acagttgctg gtaaaatgct cccagctatc ggttttgcga tgatcttgtc
    15961 agtgatggct aagaaagagt tgattccctt tgtcttgttg ggatatgttt gtgcagctta
    16021 tctaaacatc ccaacaattg gtattgcaat tgtaggtact atctttgctt tgattgaatt
    16081 ttataacaag ccaaaaacag cggatcatgt ggtagaggag gaagcacacg atgactggat
    16141 ctaacaaatt aacaaaacgt gattatctta aaacgtcttt gcgggcattc ttttgtcaaa
    16201 atggatttaa ctatagtaac tatcaagggt tgggatatgc caatgtgatg tatcctgctt
    16261 tgaaaaaaca ctatggagag gatcaggaag gtttctacca agccttggaa gaaaactgtg
    16321 aattctataa taccaaccca cacttcctgc cttttattac cagcttgcat cttgtaatgt
    16381 tggaaaatgg ccgtccggca aaagaaacac gtagtatcaa gatggccttg atgggaccat
    16441 tggcaggtat tggggattct ctttctcaat tctgtttagc tccattgttc tcaaccatcg
    16501 cagcttcgtt tgctcaagaa ggcttggttg tcggcccaat cttgttcttc cttgcgatga
    16561 atacgatttt aacagcgatt aaattgtcaa ctggtttgta tggatacaaa ctaggaacaa
    16621 ctgtgattga taaactaagc gaacagatgg caacgatttc tcgtattgcc aatattatcg
    16681 gtgtaaccgt aattgctggt ttggcagcga catctgttaa gattatggtg ccgattacct
    16741 ttgctgcagg ggaagttaaa gcagacgcta aacaaagtat cgtaagtatt cagggaatgc
    16801 ttgataaggt tgctccagct cttctaccag ccctatttac acttttagtt tactacttga
    16861 tcaaagaaaa gaaatggaca acatataaac tcgttatttt aacagttatc atcggaatta
    16921 tcggaagctg gcttaagatt atagcttaat ggatacaaca ttgttttatg gaatagtgat
    16981 tgtcttggca gtgagtcccc ttttactgtc aagctttcat tctattcgtc agcaaaagtt
    17041 gcttcgcaaa cagatggagc aacgacaaga gtatttagct tctttaacat ctggtgatga
    17101 agtgttgtta ttgtctggaa ttcatggaaa aatcatttct atcaaagatg acttggtctc
    17161 cttgcagatt gcaaaaggtg tggtcatcta tgtagaaaag gaaagtgtaa tgggaaagac
    17221 aaaagaactg ctttttaagt agttcttttt ctggtaatag ataatgaaag aagaaagaag
    17281 acaatttttt gaaagaatcg atggaaacca atgtcgtgat tatatcttgt cccactgttc
    17341 aaaagactat gagaaagtca agagttccct tgaacgcttg atggacaatc gttttatgtt
    17401 tgatagtcct tgggatatgg agccttgttc aaaaatccat caaatccagc cgatggtatg
    17461 ggatcaagta tttgaagatg atccagaatg ggcttatatg ctcaatcgac aagaatatct
    17521 cttgcagttt atgatagggt atgtggtaga aggagataag gactatattc aaaagtgcaa
    17581 gttctttcta tttgattgga ttgagcaggt gagagaattt tctcctcaat ccttgatgac
    17641 tagaaccttg gatacgggta ttcgttcctt tacttggttg aaactactct tgctcctctt
    17701 gaaatttgac ttgctagagg agaaagaact agagaaaatt ttggtcagtc tagaaaagca
    17761 gattgacttt atgaaaagct actatcgcgc caagtacacc cttagtaact gggggatttt
    17821 acaaacaatt ccgatgcttg ctatctatca tttctttgca gataagatgg acctagaaga
    17881 agcttaccat tttgcttcag aggagttgaa acagcaaatt gagacacaga ttttaggaga
    17941 tggaagccag tttgaacagt cgattctcta tcatgtagag gtttataaag ccttgctgga
    18001 tttgtgtctc ttgcttccag acttgcaaga tagttaccaa gagttgctgg aaaagatggc
    18061 gacctatatt caaatgatga caggcttaga tggacgaact ttggcttttg gtgatagcga
    18121 ttctacagaa acgacagaaa ttttgagcct gtctgctgtg gttttgaaca aggaagacct
    18181 tcttaacggt ctggatgtta aagtcgattt gcttagcctc ttgttcctgg ggcgagaaaa
    18241 ggtcaagcga ctgcaggaat ttgaaaagag agcttggcag cctaagtcca tgatctttga
    18301 agactctgga catgtctgca ttaaggatga acatcgttat ctatttttca aaaatggtcc
    18361 gctaggaagt gcccatagcc atagtgacga gaatagtttt tgcttacagt atcaaggcca
    18421 acctattttc atagatgctg ggcgttattc ttatcgggag atatatgaac gttatctctt
    18481 aaagagtgct tggagtcatt cgacctgcat tgtagatggg aaagctccgg aaagaatcac
    18541 gggatcctgg gaatatgaat actatcctca ctccctgttt tgtcaccata aagaaaggga
    18601 gggaatgcat tatattgaag gggcttattg gtcagcagaa cctgatttgc cttatcttca
    18661 caagagaaaa atcctcatgt tggtagagga tgtctggctc ttggtagatg acatcaggtg
    18721 tcaaggtcag catgaggcgt tgactcagtt tatccttgac aaggatgtga cctatcaaga
    18781 tgggaaaatc aatcagttga gactatggag tgaagttgat tttgatttgg aagataccat
    18841 catttctcct aaatacaatg agcttgaaag aagtagcaaa ctcaccaagc gccaattctt
    18901 tgagaatcag atgctggatt ataccatcat tgcgcatgag agttttgaaa tcatccgtca
    18961 ttctgtctac cagacagatg atcgtgaagt ggaaaatgct ctggcttttg aagtgaaaaa
    19021 tgacgaaaca gacaagctga ttctgttatt aagcgaggat attggtgtag gtgaaaaatt
    19081 gtgcctcgtt gacggaacaa aaatgcgtgg aaaatgtcta gtatatgata aaataaatga
    19141 gagaatgatt cgcttgcagt gctagaaata ggcattttga atagtgaata tgttataata
    19201 agtattagta ggaggtgttt tagattggag aagaaactga ccataaaaga cattgcggaa
    19261 atggctcaga cctcgaaaac aaccgtgtca ttttacctaa acgggaaata tgaaaaaatg
    19321 tcccaagaga cacgtgaaaa gattgaaaaa gttattcatg aaacaaatta caaaccgagc
    19381 attgttgcgc gtagcttaaa ctccaaacga acaaaattaa tcggtgtttt gatcggtgat
    19441 attaccaaca gtttctcaaa ccaaattgtt aagggaattg aggatatcgc cagccagaat
    19501 ggctaccagg taatgatagg aaatagtaat tacagccaag agagtgagga ccggtatatt
    19561 gaaagcatgc ttctcttggg agtagacggc tttattattc agccgacctc taatttccga
    19621 aaatattctc gtattatcga tgagaaaaag aagaaaatgg tcttttttga tagtcagctc
    19681 tatgaacacc ggactagctg ggttaaaacc aataactatg atgccgttta tgacatgacc
    19741 cagtcctgta tcgaaaaagg ttatgagcat tttctcttga ttacagcgga tacgagtcgt
    19801 ttgagtactc ggattgagcg ggcaagtggt tttgtggatg ctttaacaga tgctaatatg
    19861 cgtcacgcca gtctaaccat tgaagataag catacgaatt tggaacaaat taaagaattt
    19921 ttacaaaaag aaatcgatcc cgatgaaaaa actctggtat ttatccctaa ctgttgggcc
    19981 ctacctctag tctttaccgt tatcaaagag ttgaattata acttgccgca agttgggttg
    20041 attggttttg acaatacgga gtggacttgc ttttcttctc caagtgtttc gacgctggtt
    20101 cagccctcct ttgaggaagg acaacaggct acaaagattt tgattgacca gattgaaggc
    20161 cgcaatcaag aagaaaggca acaagtcttg gattgtagtg tgaattggaa agagtcgact
    20221 ttctaaaatg aaggaaaatg acttgcaatc tctgttaaga aataaaataa tcccacctag
    20281 cttgttctag gtgggattat ttgcctatga aatgagaaat tatgggagca agctcctaaa
    20341 tcaactgttt ttgatctact tctttaacta cttgataaaa gttatagaag taggccaaac
    20401 ttgaaatgat ggttacgact aggaatattg aaaatttcca ttggacaggg ttggttaaaa
    20461 gttgtggaaa ggatatgagg agaaagaaga gggctgcgtt gaggacaggt atccgttttg
    20521 attgtatttt ctcaagtcct ttattgagcg caggaagaaa gaggagtagg agtagtaaaa
    20581 ctgtatgaga aacagctcct gaaataaggg cgaagaaaag gaaaatactg ataaaaacat
    20641 gaatgttcag tagtctagct agtgatttca taaggcacct cctaatcctg gtctttttta
    20701 gctcttgcaa tacgaagtga gtcgacaata tgtatcatca ctccgaaaaa gaaagctccc
    20761 agtatagttt taaaaatatg ttttgtattt agaagagaac tgataaaatt tggattttca
    20821 cttgttaggg tatcaatgag tggaattata aaaaatatca ctgttccata aatcgaacct
    20881 gctttcagac caggataacg taactgtttc ttttcttttt tcatgagttt cctcctaatc
    20941 ctcatcttga tttttcttag tttttgcaat gcgacgggag atgaggaact gtatgctcgc
    21001 tccgaagaaa atagaaccga gaatacttga tacaccattt cttatagtga gaagagaatg
    21061 aaaatagtcc tgaccttcat ctatgagtat actgagaaga ggagttataa aaaacatcca
    21121 tagaccaaag aacaaacctg ctttaagacc tgggtagtgt agttgcttgc tttctttctc
    21181 attcagcata tctggttcaa tgactgtgat gcctgttttt ttcatttggt aggtgacata
    21241 gccagcagcg atgagggcaa ttactaaaat cagaggagga tagattagag ccacttcttg
    21301 agggtattta taggccagaa ggagtggaat aagatttccg aaaatcatca gataaaagag
    21361 gacgataaag acttggttcc caatactatc ggcctcacgc cgtttgtatt cgtcaagggg
    21421 accagaaata ccgtatgtgc gtttgatcag tttttcagtg aaggtttctt ttttcatgag
    21481 tttgctcctt ttttaaaaat cttcctccca aaagagactg ttgaggtcag tttggaggct
    21541 gcgggcgaga ttgagacaga gttccaaggt tggattgtac ttgtcgtttt caatcatatt
    21601 gatagtctgt ctcgagacac cgatatcctt ggcgagttcg agctgggaaa tacccaattc
    21661 cttgcgaaat tctttcacac gattcatctg gtctcctttc tgatttatgt cgtatatatt
    21721 tgactatatt atagtctttt aaacataaag tgtcaagtat ttttgacata ttttttgaag
    21781 aaatagtagt ctccttgtcc tatttgtctg acaagtgcaa gctggtcgga tttgtggtaa
    21841 aatagataag atatgacaaa agaatttcat catgtaacgg tcttactcca cgaaacgatt
    21901 gatatgcttg acgtaaaacc tgacggtatc tacgttgatg cgactttggg tggagcaggc
    21961 catagcgagt atttattaag taaattaagt gaaaaaggcc atctctatgc ctttgaccag
    22021 gatcagaatg ccattgacaa tgcgcaaaaa cgcttggcac cttacattga gaagggaatg
    22081 gtgaccttta tcaaggataa cttccgtcat ttacaggcac gtttgcgcga agctggtgtt
    22141 caggaaattg atggaatttg ttatgacttg ggagtgtcta gtcctcaatt ggaccagcgt
    22201 gagcgtggtt tttcttataa aaaggatgcg ccactggaca tgcggatgaa tcaggatgct
    22261 agtctgacag cctatgaagt ggttaatcat tatgactatc atgatttggt tcgtattttc
    22321 ttcaaatacg gtgaggataa attctctaaa cagattgcgc gtaagattga gcaagcgcgt
    22381 gaagtgaagc cgattgagac aacgactgag ttagcagaga ttatcaagtt ggtcaaacct
    22441 gccaaggaac tcaagaagaa gggtcatcct gctaagcaga ttttccaggc tattcgaatt
    22501 gaagtcaatg atgaactggg agcggcagat gagtccatcc agcaggctat ggatatgttg
    22561 gctctggatg gtagaatttc agtgattacc tttcattcct tagaagaccg cttgaccaag
    22621 caattgttca aggaagcttc aacagttgaa gttccaaaag gcttgccttt catcccagat
    22681 gatctcaagc ccaagatgga attggtgtcc cgtaagccaa tcttgccaag tgcggaagag
    22741 ttagaagcca ataaccgctc gcactcagcc aagttgcgcg tggccagaaa aattcacaag
    22801 taagagggaa aaagatggca gaaaaaatgg aaaaaacagg tcaaatacta cagatgcaac
    22861 ttaaacggtt ttcgcgtgtg gaaaaagctt tttacttttc cattgctgta accactctta
    22921 ttgtagccat tagtattatt tttatgcaga ccaagctctt gcaagtgcag aatgatttga
    22981 caaaaatcaa tgcgcagata gaggaaaaga aaaccgaatt ggacgatgcc aagcaagagg
    23041 tcaatgaact attacgtgca gaacgtttga aagaaattgc caattcacac gatttgcaat
    23101 taaacaatga aaatattaga atagcggagt aagatatgaa gtggacaaaa agagtaatcc
    23161 gttatgcgac caaaaatcgg aaatcgccgg ctgaaaacag acgcagagtt ggaaaaagtc
    23221 tgagtttatt atctgtcttt gtttttgcca tttttttagt caattttgcg gtcattattg
    23281 ggacaggcac tcgctttgga acagatttag cgaaggaagc taagaaggtt catcaaacca
    23341 cccgtacagt tcctgccaaa cgtgggacta tttatgaccg aaatggagtc ccgattgctg
    23401 aggatgcaac ctcctataat gtctatgcgg tcattgatga gaactataag tcagcaacgg
    23461 gtaagattct ttacgtagaa aaaacacaat ttaacaaggt tgcagaggtc tttcataagt
    23521 atctggacat ggaagaatcc tatgtaagag agcaactctc gcaacctaat ctcaagcaag
    23581 tttcctttgg agcaaaggga aatgggatta cctatgccaa tatgatgtct atcaaaaaag
    23641 aattggaagc tgcagaggtc aaggggattg attttacaac cagtcccaat cgtagttacc
    23701 caaatggaca atttgcttct agttttatcg gtctagctca gctccatgaa aatgaagatg
    23761 gaagcaagag cttgctggga acctctggaa tggagagttc cttgaacagt attcttgcag
    23821 ggacagacgg cattattacc tatgaaaagg atcgtctggg taatattgta cccggaacag
    23881 aacaagtttc ccaacgaacg atggatggta aggatgttta tacaaccatt tccagccccc
    23941 tccagtcctt tatggaaacc cagatggatg cttttcaaga gaaggtaaaa ggaaagtaca
    24001 tgacagcgac tttggtcagt gctaaaacag gggaaattct ggcaacaacg caacgaccga
    24061 cctttgatgc agatacaaaa gaaggcatta cagaggactt tgtttggcgt gatatccttt
    24121 accaaagtaa ctatgagcca ggttccacta tgaaagtgat gatgttggct gctgctattg
    24181 ataataatac ctttccagga ggagaagtct ttaatagtag tgagttaaaa attgcagatg
    24241 ccacgattcg agattgggac gttaatgaag gattgactgg tggcagaatg atgacttttt
    24301 ctcaaggttt tgcacactca agtaacgttg ggatgaccct ccttgagcaa aagatgggag
    24361 atgctacctg gcttgattat cttaatcgtt ttaagtttgg agttccgacc cgtttcggtt
    24421 tgacggatga gtatgctggt cagcttcctg cggataatat tgtcaacatt gcgcaaagct
    24481 catttggaca agggatttca gtgacccaga cacaaatgat tcgtgccttt acagctattg
    24541 ctaatgacgg tgtcatgctg gagcctaaat ttattagtgc catttatgat ccaaatgatc
    24601 aaactgctcg gaaatctcaa aaagaaattg tgggaaatcc tgtttctaaa gatgcagcta
    24661 gtctaactcg gactaacatg gttttggtag ggacggatcc ggtttatgga accatgtata
    24721 accacagcac aggcaagcca actgtaactg ttcctgggca aaatgtagcc ctcaagtctg
    24781 gtacggctca gattgctgac gagaaaaatg gtggttatct agtcgggtta accgactata
    24841 ttttctcggc tgtatcgatg agtccggctg aaaatcctga ttttatcttg tatgtgacgg
    24901 tccaacaacc tgaacattat tcaggtattc agttgggaga atttgccaat cctatcttgg
    24961 agcgggcttc agctatgaaa gactctctca atcttcaaac aacagctaaa gctttggagc
    25021 aagtaagtca acaaagtcct tatcctatgc ctagtgtcaa ggatatttca cctggtgatt
    25081 tagcagaaga attgcgtcgc aatcttgtac aacccatcgt tgtgggaaca ggaacgaaga
    25141 ttaaaaacag ttctgctgaa gaagggaaga atcttgcccc gaatcagcaa gtccttatct
    25201 tatctgataa agcagaggag gttccagata tgtatggttg gacaaaggag actgctgaga
    25261 cccttgctaa gtggctcaat atagaacttg aatttcaagg ctcgggctct actgtgcaga
    25321 agcaagatgt tcgtgctaac acagctatca aggacattaa aaaaattaca ttaactttag
    25381 gagactaata tgtttatttt catcagtgct ggaattgtga catttttact aactttagta
    25441 ggaattccgg cctttatcca attttataga aaggcgcaaa ttacaggcca gcagatgcat
    25501 gaggatgtca aacagcatca ggcaaaagct gggactccta caatgggagg tttggttttc
    25561 ttgtttactt ctgttttggt tgctttcttt ttcgccctat ttagtagcca attcagcaat
    25621 aatgtgggaa tgattttgtt catcttggtc ttgtatggct tggtcggatt tttagatgac
    25681 tttctcaagg tctttcgtaa aatcaatgag gggcttaatc ctaagcaaaa attagctctt
    25741 cagcttctag gtggagttat cttctatctt ttctatgagc gcggtggcga tatgctttct
    25801 gtctttggtt atcaagtgca tctagggatt ttctatattg tcttcgctct tttctggcta
    25861 gtcggttttt caaacgcagt aaacttgaca gacggtgttg acggtttagc tagtatttcc
    25921 gttgtgatta gtttgtctgc ctatggagtt attgcctatg tgcaaggtca gatggatatt
    25981 cttctagtga ttctggccat gattggtggt ttgctcagtt tcttcatctt taaccataag
    26041 cctgctaaga tctttatggg tgatgtggga agtttggctt taggtggaat gctggcagct
    26101 atctctatgg ctctccacca agaatggact ctcttgatta tcggaattgt gtatgttttt
    26161 gaaacaactt ctgttatgat gcaagtcagt tatttcaaac tgacaggtgg taaacgtatt
    26221 ttccgtatga cgcctgtaca tcaccatttt gagcttgggg gattgtctgg taaaggaaat
    26281 ccttggagcg agtggaaggt tgacttcttc ttttggggag ttgggcttct agcaagtctc
    26341 ctgaccctag caattttata tttgatgtaa gaatggcacc ctgatgtttt agggtgtttt
    26401 tgtgtttaaa tacacaatga aaatcaaaga acaaactaga aagctaactt taggctgctc
    26461 aaaacatagt atattgaaac taaaatagta cacctctact tctaaaatat tgttagaaat
    26521 cgatttgact gtcctgaacg atttatcctg ttcttatttc attttactat acagttttga
    26581 gatggttgat agaactgacg aagtcagctc aaaacacggt tttgaggttg tagataagga
    26641 gaagctgatg tggtttgaag aggttttcga agagtgtaaa aaaatattgg tcagttaaag
    26701 tcaaaactat tgaccttttc tgactaatgt agtatattat gaacgtaagg taaatgaaag
    26761 ccttactaga acacttattt aaagtaaaat agaaagaggt gagcctatgt ttcatctaga
    26821 aatcttcaga agtaaagata gtctactcct gcttgaaaaa gaaaaaccag aaatagtacg
    26881 tagagtagcg gtttagctag tctaaatttt ttaaaacaaa ggtcaaagat agtcaatatc
    26941 agtaatcata actaagtaaa caaaaagagg taaagaatat gaataacaac tttaataatt
    27001 ttaataacat ggatgattta tttaaccaat tgatgggtgg tatgcgagga tacagttctg
    27061 aaaatcgccg ttacttaatt aatggacgcg aagtcacacc tgaggaattt gctcactatc
    27121 gtacgactgg tcaattacca ggaaatgcag aaactgatgt gcaaatgcca caacaggcat
    27181 caggtatgaa acaagacggt gtccttgcaa aactaggtcg aaacttgaca gcagaagcgc
    27241 gtgagggcaa gttggatcct gttatcggac gaaacaagga aattcaagaa acatctgaaa
    27301 tcctctcacg ccgcaccaag aacaatcctg ttttggtcgg agatgcaggt gttggtaaga
    27361 cagcagttgt cgaaggtcta gcgcaagcca ttgtgaacgg agatgttcct gctgctatca
    27421 agaacaagga aattatttct attgatatct caggtcttga ggctggtact caataccgtg
    27481 gtagctttga agaaaatgtc caaaacttag tcaatgaagt gaaagaagca gggaatatta
    27541 tcctcttctt tgatgaaatt caccaaattc ttggtgctgg tagcacttgt ggagacagtg
    27601 gttctaaagg gcttgcggat attctcaagc cagctctctc tcgtggagaa ttgacagtga
    27661 ttggggcaac aactcaagac gaataccgta acaccatctt gaagaatgct gctcttgctc
    27721 gtcgtttcaa cgaagtgaag gtcaatgctc cttcagcaga gaatactttt aaaattcttc
    27781 aaggcattcg tgacctctat caacaacacc acaatgtcat cttgccagac gaagtcttga
    27841 aagcagcggt ggattattct gttcaataca ttcctcaacg tagcttgcca gataaggcta
    27901 ttgaccttgt cgatgtaacg gctgctcact tggcggctca acatccagta acagatgtgc
    27961 atgctgttga acgagaaatc gaaacggaaa aagacaagca agaaaaagca gttgaagcag
    28021 aagattttga agcagctcta aactataaaa cacgcattgc agaattggaa aggaaaatcg
    28081 aaaaccacac agaagatatg aaagtgactg caagtgtcaa cgatgtggct gaatctgtgg
    28141 aacgaatgac aggtatccca gtatcgcaaa tgggagcttc agatatcgaa cgtttgaaag
    28201 atatggctca tcgcttgcaa gacaaggtga ttggtcaaga taaggccgta gaagctgtag
    28261 ctcgtgctat ccgtcgtaac cgtgctggtt ttgatgaagg aaatcgccca atcggcagct
    28321 tcctctttgt agggtctact ggggttggta agacggagct tgctaagcaa ttggcactcg
    28381 atatgtttgg aacccaggat gcgattatcc gtttggatat gtctgaatac agtgaccgca
    28441 cagctgtttc taagctaatt ggtacaacag caggctatgt gggttatgat gacaatagca
    28501 ataccttaac agaacgtgtt cgtcgcaatc catactctat cattctcttg gatgaaattg
    28561 aaaaggctga tcctcaagtt attacccttc tcctccaagt tctagatgat ggtcgtttga
    28621 cagatggtca aggaaataca gtaaacttca agaacactgt cattattgcg acctcaaatg
    28681 ctggatttgg ctatgaagcc aacttgacag aagatgcgga taaaccagaa ttgatggacc
    28741 gtttgaaacc cttcttccgt ccagaattcc tcaaccgctt taatgcagtc atcgagtttt
    28801 cacacttgac taaggaagac ctttctaaga ttgtagattt gatgttggct gaagttaacc
    28861 aaaccttggc taagaaagac attgacttgg tagtcagtca agtggctaaa gattatatca
    28921 cagaagaagg ttacgacgaa gtcatggggg ttcgtcctct ccgtcgcgtg gttgaacaag
    28981 aaattcgtga taaggtgaca gacttccact tagatcattt agatgctaaa catctggaag
    29041 cagatatgga agatggcgtt ttggttattc gtgagaaagc ctaagataga attttgagga
    29101 taaaaaagaa ggagccagct gaaaaaaact ggttcctttt gaggtacgac gggcatgtcg
    29161 tatagtagaa gtgtactatt ctagtttcaa tatactatag tagctcagaa gtcgatactt
    29221 aaacgtgcta tatcaaaacc agtccttgaa aaacgcggac tggtttcgtg tttggattat
    29281 taccttgaac gacatgcgtt aaaagttagt tgaaccgccg tatgccgaat ggtacgtacg
    29341 gtggtgtgag aggggctaga gattatcccc tactcgattt taaatcacat gacgttcaaa
    29401 ggcatcatct gaaatccctt gttccaagat gagttttgcc cattctttag cagagaagag
    29461 gctgtggtcc ttgtagtttc cgcaagattc gatggttgtc cctgggacat cttcccaagt
    29521 agtagtttca gcgatttcct tgagcgaatc cttgataaca gctgcgattt tagcactggt
    29581 gtgacgtccc cacataatca tgtggaagcc tgtgcggcaa ccaaatggtg aacagtcaat
    29641 catgccgtca atgcgggtac ggatgagttt ggctaagagg tgctcgatag tgtgaaggcc
    29701 ggcagtaggg atagagtctt cgtttggttg caccaagcga atatcataat tggagatgat
    29761 gtctcctttg ggtcctgttt cttccccaat caagcgaaca tagggtgctt tgacaatggt
    29821 gtggtcaagt tcaaaacttt cgacaataac ttcttttgac atggtaaatc ctttcagttt
    29881 tcttctctca ttatatcata aaggttgctc ctgagacaga gagaaaacct ctccgaggct
    29941 ggagaggttg aaatctttac ttacgatata agcggtcgta ttggtagtat gggtcaaagg
    30001 ttacgttgat acccagttta cgaaggacat tcttgtcttc atcagtcaag atgatggttg
    30061 agtgggcttc gcttcctttg aggttgccga gttcttccat agcgcgggca gcatcaggat
    30121 tttctgtagc tgtgatagca agtgcaatca ggatttcatt tgaatgaagg cgtggattgc
    30181 ggctaccgag atgatcgatt ttaagacctt ggattggctt aacaacttca ggctcgatta
    30241 gttttacttc tttagcgatg tcagctgatt ttttgatggc gttgatcaag gcagcggctg
    30301 taggaccaaa gagttctgag ttcttaccag tgacgatttc cccatttggc aattcaaagg
    30361 ctagggctgg tccaccagtt tcttctgctt tttggcgcgc aacgacagca accttacggt
    30421 ctgcaggtgt gataccgagg tcgttcatga gcaactcaat tttcttgacg gcagcttcgc
    30481 caactttttc agctttgaag tcaagaactg tttgatagta acggcggatg atttcttgtt
    30541 tagaagcttc gacagcagcc tcgtcatctg taatagcgaa accaaccatg ttgacaccca
    30601 tatctgtcgg tgaagcgtat ggtgattttc cgagaatacg ttccaacatg cgcttgagca
    30661 ctgggaagat ttcgatatca cggttgtagt tgacagtggt ttctccatag gtttgaagat
    30721 ggaaggggtc aatcatgttg acatcatcaa ggtcagctgt ggcagcttca taagccaagt
    30781 taactggatg atgaagggga agattccaaa cagggaaggt ttcaaattta gcgtagccag
    30841 acttgatgcc attgatttgg tcgtggtaca tattggacat acacgttgcc aattttccag
    30901 aaccgggtcc aggagcggtt acgacaatca agttgcgact gattttgatg tagtcgtttt
    30961 tgcccatgcc ttctggggaa atgatgtgat ccatatccgt cggatatcct ttgattggat
    31021 aatgaagata agaatcaatt ccgtttttct caagttggtt gcggaaggca tctgcagcgg
    31081 gttgaccagt gtattgtgta atgacaacgg aaccaacaaa aatccctaat tcattgaatt
    31141 tgtcaatcaa acgaagaact tcttggtcat aagaaatgcc taagtcgcca cgtgctttgg
    31201 aatgttcaat gttgctagca ttaatggcaa tcacaacctc aacctgctct ttcaattctt
    31261 gcaagagctt gattttgttg tcaggttcat aaccaggaag gacacgagca gcgtggaaat
    31321 cttctaacat tttaccgcca aactctaagt agagcttgcc gtcaaattgg ttaatgcgct
    31381 ccaaaatatg gtcgcgttgt aaattcaaat attgttcaga actaaaagct tgttttttca
    31441 ttttttacct ctggactcta ttataataaa aaattggaag ttaggaaact acggagctaa
    31501 aaaagaaatt aaaaagatta agcaaacgct tgcacaaaat tttaaaaagt gctatcatat
    31561 actatagatt attaaaataa tgaggtaaga agatgcaaga aaaatggtgg cataatgccg
    31621 tagtctatca agtctatcca aagagtttta tggatagtaa tggagatgga gttggtgatt
    31681 tgccaggtat taccagtaag ttggactatc tagctaagct aggaatcaca gcgatttggc
    31741 tttctcccgt ttatgacagc cctatggatg ataatggcta cgatattgct gattatcaag
    31801 cgattgcggc tatttttgga accatggagg acatggatga actgattgca gaagctaaga
    31861 agcgtgatat ccgtatcatc atggacttgg tggtcaatca tacctcggat gagcatgcct
    31921 ggtttgtaga ggcctgtgaa aatcctaata gccctgagcg agactactat atctggcgcg
    31981 atgaacccaa tgacctagat tctatcttta gtgggtctgc ttgggaatac gatgaaaagt
    32041 caggtcaata ctatctccac tttttcagca agaaacagcc ggatctcaac tgggaaaatg
    32101 aaaaacttcg ccagaaaatt tatgagatga tgaacttctg gattgataag ggtattggtg
    32161 gtttccgtat ggatgttatt gacatgattg gcaaaattcc tgacgagaag gtagtcaata
    32221 atggtcctat gctccatccc tatctcaagg aaatgaatca ggcgaccttt ggagataagg
    32281 atctcttgac agtaggggag acttggggag caacgccaga gattgccaaa ctctactctg
    32341 atccaaaggg gcaagaattg tctatggtct tccagtttga acatatcggt cttcagtatc
    32401 aggaaggtca gcctaaatgg cactatcaaa aagagctgaa tatcgctaag ttaaaagaaa
    32461 tcttcaacaa atggcagaca gagttaggag ttgaggacgg ctggaattcc ctcttctgga
    32521 acaaccatga cctccctcgt attgtctcaa tctggggaaa tgaccaagaa taccgcgaaa
    32581 aatctgccaa agcctttgca atcttgcttc atcttatgag aggaactcct tatatctacc
    32641 aaggtgagga gattgggatg accaactatc cgtttgaaac actggatcaa gtagaagata
    32701 ttgaatctct caactatgcg cgtgaggctc ttgaaaaagg tgttccgatg caagaaatca
    32761 tggacagtat ccgtgttatt ggacgtgaca atgcccgtac ccctatgcaa tgggacgaga
    32821 gcaaaaacgc tggtttctca acaggtcaac cttggttggc agttaatcca aattacgaga
    32881 tgatcaacgt ccaagaagcg ctggcaaatc cagattctat tttctatacc tatcagaaac
    32941 tggtccaaat tcgcaaggag aatagttggc taattcgagc tgactttgaa ttgcttgata
    33001 cggctgataa ggtctttgct tatatacgta aggatggcga ccgtcgcttc ctagttgtgg
    33061 ctaacttgtc caatgaagag caagacttga cagtagaagg aaaagtcaaa tctgtcttga
    33121 ttgaaaacac cctagctcaa gaagtctttg aaaaacaaat cttagttcca tgggatgctt
    33181 tctgtgtgga attactataa atattttttg cagaaaaatt taaaattgaa atcgtataaa
    33241 aacaagggag gactgtataa aagacagaaa tcctttgttt tttataacca aagtttataa
    33301 accttcattc ttgaaattca attaacttta caaattccca ctattaagga gaaagaagat
    33361 gaacataaag aagcgtgtcc ttggtgcagg tctgactttt gcatctgctt tgcttttagc
    33421 tgcttgcggc caatcaggtt cagatacaaa aacttactca tcaaccttta gtggaaatcc
    33481 aactacattt aactatctat tagactatta cgctgataat atagtcaatt gaaacaagag
    33541 caggacaaaa gagcctcgta aaaggtattg caacaacttg gtaatacctt tttgaggtgc
    33601 tttttgatat gagcccatgt tttctcaata ggattgtact caggtgagta gggaggaaga
    33661 ggtaaaagtt tatgcccaaa ctcttcgcat aaaagttcta gcttccccat tctatggaat
    33721 cttgcattat ccataataat aaccgatggt gtggttaatg ttggtaagag aaacttctga
    33781 aaccaagctt caaaaaagtt gctcgtcatc gtctcttcgt aagtcattgg agcgattaac
    33841 tcaccattca tttgttagac ctgcaaccaa agaaattctc tgatatcttc ttccagatac
    33901 tttgcctctt cttaactgac cttttaatga gcgaccatat tctcgataaa aataagtatc
    33961 gaatcctgtt tcgtcaatct aaacaggtgc taggtgcttt aaactattaa aattcttaag
    34021 aaataaggct actttttctg ggtcttgttc ataattagat tgaaactaga atagtacacc
    34081 tctgcttcta aaacattgtt agaaatcgat ttgactgtcc tgatcgattt gtcctgttct
    34141 tatttcattt tactatattt ttggttcgcg ggaagtctac taagatactt aaagatacag
    34201 atagtgaaaa taaaggtgta gacattaccg ttggtgttct ctatccttgt cagctctgtg
    34261 tcgctctttg cagtacagca gtttgttgga ctgaccaatc gtttaaatgc gacttctaat
    34321 tactcagaat attcgatcag tgtcgctgtt ttagcagata gtgagatcga aaatgttatg
    34381 caactgacga gtgtgacagc accgactggg actgataatg aaaatattca aaaattacta
    34441 gctgatatca agtcagaata ccgatttgac ggtcgaccag agttcgtctt acttggctgc
    34501 ttacaagagt ctgattgcag gtgacaccaa gaccattgtc ctaaatagtg tctttgaaaa
    34561 tatcatcgag tcagagtatc cagactacgc atcgaagata aaaaatattt ataccaaggg
    34621 atttactaaa aaagtagaag ctcctaagac gtctaagaat cagtctttca atatctaagt
    34681 tagtggaatt gacacctatg gtcctattag ttcggtgtcg cgatcagatg tcaatatcct
    34741 gatgactgtc aatcgagata ccaagaaaat cctcttgacc acaacgccgc gtgatgccta
    34801 tgtaccaatt gcagatggtg gaaataatca aaaagataaa ttgactcatg cgggcattta
    34861 tggagttgat tcgtccattc acaccttaga aaatctctat ggagtggata tcaattacta
    34921 tgtacgattg aacttcactt cgtttttgaa attgattgat ttgttggatg gaattgatgt
    34981 ttataatgat caagaattta ctgcccatac gaatggaaag tattaccctg aaggcaatgt
    35041 tcatcttgat tcagaacagg ctctcggttt tgttcgtgag cgctactccc tagcagatgg
    35101 cgatcgtgac cgcgggcgca atcaacaaaa ggtgattgtg gctatccttc aaaaattaac
    35161 gtcaaccgaa gaactgaaaa attatagtac gatcattgat agcttgcaag attctatcca
    35221 aacaaatatg ccgattgaga ctatgataga tttagtgaat actcagttgg aaagtggagg
    35281 gaattataaa gtaaattctc aagatttaaa agggacaggt cggatggatc ttccttctta
    35341 tgcaatgcca gacagtaacc tctatgtgat ggaaatagat gatagtagtt tagctgtagt
    35401 taaagcagct atacaggatg tgatgaaagg tagatgaaat gatagacatc cattcgcata
    35461 tcgtttttga tgtagatgac ggtcccaagt caatagagga tagcaaggca cttttaagag
    35521 aagcttataa tcaaggagtt cgaatgattg tgtctacttc gcatcgtcga aaagggatgt
    35581 ttgaaactcc agaagaaaaa attgtaacaa attttattaa ggttcgtgaa attgcaaaag
    35641 aagtagcaga tgatttagtc attgcttatg gcgcagagat atactatact ctggatgctc
    35701 tagaaaagct agaaaaaaag aaattcctac ccttaatgat agtcgttatg ctttgattga
    35761 gtttagcatg catacttcct atcgtgagat tcatacgaga ttgagcaata ttttgatgtt
    35821 gggaatcacg ccagtaattg ctcatattga acgttatgat gctttagaga ataacgaaaa
    35881 acgtgttcgt gaactgattg atatggggtg ctatactcag atagatagtt atcatgtttc
    35941 aaaacctaag ttctttggtg aaaaatataa attcatgaaa aagagagctc ggtatttttt
    36001 ggaacgtgat ttagttcatg tagttgcaag tgacatgcac aatttagaca gtagacctcc
    36061 atatatgcaa caggcatatg atatcattgc taagaaatat agagcgaaaa aagcgaaaga
    36121 actttttgta gataatccca gaaaaattat aatggatcaa ttaatttagg agaaaatatg
    36181 aaggaacaaa acactttgga aatcgatgta ttgcaactat tcagagcttt atggaaaaga
    36241 aagttggtca ttttattagt ggcaattata acttcttcag ttgcttttgc ctacagtact
    36301 tttgttatca aacctgagtt tactagtacg actcggattt atgtagttaa ccgtaatcag
    36361 ggagagaagt ctggtttaac caatcaagac ttgcaggcag gatcatactt ggttaaagac
    36421 tatcgtgaaa ttatcctatc gcaggatgtt ttggaggaag ttatttctga tttgaaacta
    36481 gatttgacgc caaaaggttt ggctaataaa attaaagtaa cagtaccagt tgatacccgt
    36541 attgtctctg tttcagttaa tgatcgagtt cctgaagagg caagccgtat cgctaactct
    36601 ttgagagaag tagctgctca aaaaattatc agtattactc gtgtttctga tgtggcaaca
    36661 ctggaggagg caagaccggc gatatcaccg tcttcgccaa atattaaacg caatacacta
    36721 attggttttt tggcaggggg gattggaact agtgttatag ttcttcttct tgaacttttg
    36781 gacactcatg tgaaacgtcc ggaagatatc gaagatacac tgcagatgac acttttggga
    36841 gttgtaccaa acttgggtaa gttgaaatag gagagaggaa tgccgacatt agaaatagca
    36901 caaaaaactg gagttcatta agaaggcaga agaatattac aatgccttgt gtacaaatat
    36961 acagttgagc ggagataaac taaaagtaat ttccgttact tctgttaacc ctggggaagg
    37021 aaaaacaact acttccgtaa atatagcaag gtcgtttgcg cgtgcaggct ataaaactct
    37081 tttgatcgat ggtgatactc gaaattcagt tatgtcagga ttttttaaat ctcgtgaaaa
    37141 aattacagag ctaacagaat ttttatctgg gatagctgat ttatctcacg gtttatgtga
    37201 tacaaatatt gaaaatttat ttgtagttca atcgggatct gtatcaccaa accctacagc
    37261 cttgttacaa agtaaaaatt ttgtggttat ggtaaagatt ttttcaaaag aggtcagtat
    37321 attgagttgg tggaaacgat aaaatacata atattttatt cctttggtta tcaaattagc
    37381 ccctcctgaa gctccccaat tgacggcttg agctccaatc aaagggtgtt tgtccgcttt
    37441 ttgacagagg gtaatcgcta gaggacagca aacggccata gtagtgaaaa atccagcacc
    37501 taaagcagac aaaagggttg ccatcaggta taaaatcatg tagagggcgt tagggtgggt
    37561 gcgtgtgcgg tagagaatgt gttgagccaa aacatcaaga gtaccgttag ttgttgcaac
    37621 gttataaaag agagagacgc taaaaatggt aaaaaagagt gaggttggcc aaaaatgaag
    37681 aagttctttg ggacttaatc ccatgagagt ggttgcgatg aggtaagaaa aagcaatagc
    37741 cagcaggcca atattgattt tggtgcggta accaattcca atggctagag caatggcgct
    37801 aatcattatt aaatgaatca ttgaattgtc ctttcagtta gaatatagaa agaggataga
    37861 ttgaagttcg agaatactgg gtgtcttctg atgttaagtg gttgtgtcaa aaccatccca
    37921 aatggcataa attgcgtgga attggaatga ctcgtaatac tattgataga gatggtatta
    37981 caagtcaaga cgttcgctat tttatcttta actttaagct tgatgtgatg accttttgcc
    38041 atagtgttcg aggtcattgg tcagcagaaa gtatgcattg gttattggat gtggtttatc
    38101 gtgaagacca tcatcagacc ctggataaac gagctgcttt taaccttaat cttatccgaa
    38161 aaatgtgttt atattttcta aaagtgatgg tattttctaa aaaagacctc agctatcgat
    38221 gcaaacaacg gtatatctct gtccatttgg aagattattt ggaaacagag gttaggaaag
    38281 taattagttt aacgggatat cttttcaaag ctgatactaa ggcacaaaaa aagtttgata
    38341 ttccccttga caatagataa aattattata taattaaatt attgcttttt aaataaagtg
    38401 agaatattaa taatacagag aaagaggact gtagtaaaat gaaaattgcc attgcaggaa
    38461 gtggttatgt aggactgtct ttagcggtgc tactagctca gcatcatgaa gttaaggtca
    38521 ttgatgttat aaaggataag gtagagtcga taaacaatag aaaatctcca attaaggatg
    38581 aggcgattga gaaatactta gttgaaaaag agttgaatct tgaagcctcc ttagatcctg
    38641 cacacgttta taaagacgtg gagtatgcta ttattgctac tccgactaat tatgatgtag
    38701 acttaaatca gtttgataca tcttcagttg aagctgctat caagacttgt atggaatata
    38761 atgatacttg tacaatcgta atcaaaagta ctattcctga agggtatact aaagaagtga
    38821 gggaaaagtt taatacagat cgtattattt tttctccaga gtttctacgt gaatccaaag
    38881 ctttatatga taatttgtat ccatctagaa ttgttgtagg aactgatttg gatgattctg
    38941 agttaacaaa aagagcatgg cagtttgcag atctacttaa aggtggagct attaaggaag
    39001 aggttccgat actggttgtt gcttttaatg aagcagaggt tgcaaaattg tttagtaaca
    39061 cttacttggc aactcgcgta gcttatttta atgagataga tacatatagc gaggtaaaag
    39121 ggcttaatcc caagacaatt attgatattg tttgttatga tcctagaatt ggatcatact
    39181 ataataaccc tagctttggt tacggagggt attgcttacc aaaagacaca aagcaattga
    39241 aagcaagttt tagggatgtt cctgaaaatc tgattacagc tgtggtgcaa tctaataaaa
    39301 caagaaaaga ttatatagct ggagctattc tagctaaaca acctagtgtt gtaggtattt
    39361 atagattaat tatgaaatct gattctgata attttcgttc tagtgctgtt aagggagtta
    39421 tggaacgttt ggacaattat ggtaaagaaa ttgttattta cgaacctact attgagtgtg
    39481 atacttttat gggatacaga gtaattaaat ctttagatga atttaagaat atttctgaca
    39541 ttgttgtagc gaatcgtatg cacgatgatt taagggatat acaagaaaaa ctctatacac
    39601 gcgatttatt tggcagagaa taaggggcaa taatttttat gtatacattt attttaatgt
    39661 tattggattt ttttcagaat catgattttc atttctttat gttgtttttt gtctttattc
    39721 ttattcgttg ggcggttata tattttcatg ctgtcagata taagtcctac agttgtagtg
    39781 taagtgatga gaagttattt agttctgtaa ttatccctgt cgtggatgaa ccacttaatc
    39841 tttttgaaag tgtactgaat agaatttcca gacataaacc atccgaaatt attgtggtta
    39901 ttaacggccc aaaaaacgag agacttgtaa aactttgtca tgattttaat gaaaaattag
    39961 aaaataatat gactccaatt caatgttatt acactcctgt tcctggcaag agaaatgcta
    40021 tccgcgttgg gctggagcat gtggattcgc agagtgatat tacagttcta gtagatagtg
    40081 atacagtatg gacgcctaga accttgagtg agttgctgaa gccttttgtt tgcgataaaa
    40141 aaataggtgg ggtaacgaca agacaaaaaa ttcttgaccc tgagcgtaat ctcgtgacaa
    40201 tgtttgctaa cttgttagag gaaattaggg cagaaggaac tatgaaagca atgagtgtga
    40261 ctggtaaagt agggtgctta cctggtcgaa caattgcttt tagaacagag attctcagag
    40321 agtgtataca tgagtttatg aatgaaactt tcatgggatt tcataaggaa gtttctgatg
    40381 atagaagtct tacaaatttg actttaaaaa aaggctataa aactgttatg caggatactt
    40441 ctgttgtgta tacagatgct cctacaagtt ggaaaaagtt cattagacag caactaaggt
    40501 gggcagaagg ttctcagtat aacaatctaa agatgactcc ttggatgatt agaaatgccc
    40561 ctcttatgtt ttttatttat tttacagata tgattttacc tatgctactt attagctttg
    40621 gtgtgaatat attcctgttg aaaatattaa atataactac aattgtttat acagcttcat
    40681 ggtgggaaat tattttatat gttcttttgg gaatgatttt tagctttgga ggaagaaact
    40741 ttaaagctat gtctagaatg aagtggtatt atgtatttct tattcctgtt tttataatcg
    40801 ttttgagtat aattatgtgc cctattaggc tattaggact tatgagatgt tctgatgatt
    40861 tagggtgggg aactaggaat ttaacagagt gagataaata gtagtgcgta tatagagtat
    40921 ttactcagag tattaattga tttttgaaaa ggaaaagtgt tttttaatgt taagaaagaa
    40981 cttgaaatat cagattatga cacgagctgg aacaatttta gctatcttgt ttttcattat
    41041 attagggatt attgttgaag ttttgtttta aggctcattg tcatctgtag tggctcactt
    41101 cagacgtaag ggtcatattt taatgtgaaa agagtgttaa aagattaatc acttatatta
    41161 ttttaataga aatagtgtaa ggaattgtta tgaaaaaagt aaaaaaagct gttattcctg
    41221 ctgcagggct gggcacacga tttttgcctg ccactaaagc tttggcaaaa gaaatgcttc
    41281 caattgtaga ccgccccaca attcattttg tcattgaaga agctttacgt tcgggtattg
    41341 aagatattct agtagttact ggaaagagta aacgttctat tgaagattat tttgattcaa
    41401 cttttgaatt ggaatatagt cttagaaaac aaggaaagat ggaacttctt aagtcagtta
    41461 atgaatcgac tgatattaaa gtacatttcg ttcgtcaaag ttcaccacgt ggtcttggtg
    41521 acgctgttct ccaagcgaag tcttttgttg gtgacgatcc ctttgttgta atgcttggtg
    41581 atgaccttat ggatatcacc gactcaactg ctgtaccttt aacaagacaa ttgatggatg
    41641 attacaacgc aacacaggct tcaactatcg cagtaatgcc tgttagatat gaagatgttt
    41701 cttcttatgg tgtgatttct cctagattgg aaagtagtaa tggcctctat agtgttgatg
    41761 cttttgtaga gaaaccaaaa ccagaagaag cgcctagcaa tttagctatt attggacgtt
    41821 atctacttac tcctgagatt ttttctatat tagaaaccca aaagccagga gcaggtaatg
    41881 aaattcaatt gacagatgct attgatacat tgaataagac acagagtgtt tttgcgcgtg
    41941 aatttgtggg caaacgttat gatgttggtg ataagtttaa ttttatgaaa acatcaattg
    42001 attatgctct tcaacatcct cagattaaag agagtttaaa aaattacgtt attgcacttg
    42061 gtaagcaatt ggagaagcta gatgactgtt cgtcaagtgg acacctatga attgtataga
    42121 aagttatcaa aaatggctaa atgtccctga tcttccagct tatttaaaag atgaattgct
    42181 cagcatggat gacaaaacaa aagaagacgc cttttacaca aaccttgaat tcggaacagc
    42241 tggtatgcgt ggttatattg gtgctgggac aaaccgtatt aatatctatg tggtgcgtca
    42301 agcaacagaa ggccttgcca aattagttga atcaaaaggc gaaacggcca aaaaagctgg
    42361 ggttgctatt gcctatgact cgcgacattt ttcaccagaa ttcgcttttg aatctgccca
    42421 agtattagcg gcccatggca ttaaatctta tgtttttgaa agcctacgcc ctactcctga
    42481 gctgtctttt gctgttcgtc atctcggagc atttgctggt attatggtaa ccgccagtca
    42541 taaccctgct ccttttaatg gttataaagt ttacggttct gatggtgggc aaatgcttcc
    42601 agctgatgct gatgctttaa ctgactatat tcgtgcgatt gataacccat ttgctgtagc
    42661 ccttgctgac ttagaagaag ctaaatcaac tggtcttatt gaagtaattg gtgaaactct
    42721 cgattctgcc taccttgaag aggttaaaag cgttaatatc aatcaagatt tgattgacca
    42781 atacggtcgc gatatgaaaa ttgtctacac acctcttcat ggtactggag aaatgttagc
    42841 acgtcgagct ttagcacaag ctggtttcga atctgttcaa gttgtcgaag ctcaagcaaa
    42901 accagcccca gacttctcaa cagttgcatc accaaaccct gaaagtcaag ccgcctttgc
    42961 cttagctgaa gaactagggc gtcaagtcga tgctgatgta ttagtggcga ctgaccctga
    43021 tgctgaccgt ctcggtgttg aaattcgtca agctgatggc agttattgga acctttctgg
    43081 taaccaaatc ggtgctctta tcgccaaata cattttagaa gctcacaaac aagctgggac
    43141 actcccaaag aatgctgcat tggcaaaatc aatagtatca actgaattag tcaccaaaat
    43201 tgcggaaagc tatggtgcaa ccatgtttaa cgtgttaaca ggtttcaaat tcatcgctga
    43261 gaaaattcaa gaatttgaag aaaaacataa ccatacctac atgtttgggt ttgaagaagg
    43321 ctgatgagtt tattgattgc ctccagcttg gagttagaat agggcatctg gatggtattt
    43381 gtcacgtatt ttctgtagcg aaccagcgtg ctaagagcag ttctaaaggc ttgattgagt
    43441 tggggaaaag cctcagttaa caagtcaaag aaatggtcgg cattcttttc ttgcaggtgg
    43501 aaaagcagga gctggtaaag atcgtcataa tagtggagct catctgagaa agctaaggtt
    43561 ttattgacga tttctcgagg tgtcagtgtc tgtctaaaag ttcttgagta gaaggcctta
    43621 tcagacagtt ttcggctatc tttttggaaa attcgccagt gatttttcat ggcgcgatag
    43681 ggaagtgatt gcttgtcaaa attcttcatg atgacaattc tggttgtcat catctcacgg
    43741 cttaggtgct ggatgatatg aaatctatca aggacgattt gtgcatttgg aaataggcat
    43801 ttaatcacaa gactctatta cgtatctagt tggtacaaat attgaccgtc agtcctataa
    43861 atatacatct aagaccagtg aagaacaaaa aacatctacg aaaaaggctc tcttaaacaa
    43921 ggatttccgt caggctattg catttggatt tgaccgtaca gcctatgcct ctcagttgaa
    43981 tggacaaact ggagcaagca aaatcttacg taatctcttt gttccaccaa catttgttca
    44041 agcagatggt aaaaactttg gcgatatggt caaagagaaa ttggtcactt atggggatga
    44101 atggaaggat gttaatcttg cagattctca ggatggtctt tacaatccag aaaaagccaa
    44161 ggctgaattt gctaaagcta aattagcctt acaagcagaa ggagtccaat tcccaattca
    44221 tttagatatg ccagttgacc agacagcaac tacaaaagtt cagcgcgtcc aatctatgaa
    44281 acaatccttg gaagcaactt taggaactga taatgtcatt attgatatcc aacaactaca
    44341 aaaagacgaa gtaaacgata ttacatattt tgctgaaaac gctgctggcg aagactggga
    44401 tttatcagat aatgtcggtt ggggtccaga ctttgccgat ccatcaacct accttgatat
    44461 catcaaacca tctgtaggag aaagtactaa aacatattta gggtttgact caggggaaga
    44521 taatgtagct gctaaaaaag taggtctata tgactacgaa aaattggtta ctgaggctgg
    44581 tgatgaggct acagatgttg ctaaacgcta tgataaatac gctgcagccc aagcttggtt
    44641 gacagatagt gctttgatta ttccaactac atctcgtaca gggcgtccaa tcttgtctaa
    44701 gatggtacca tttacaatac catttgcatt gtcaggaaat aaaggtacaa gtgaaccaat
    44761 cttatataaa tacttggaac ttcaagacaa ggcagtcact gtagatgaat accaaaaagc
    44821 tcaggaaaaa tggatgaaag aaaaagaaga gtctaataaa aaggctcaag aagatctcgc
    44881 aaaacatgtg aaataactgt tgcaaaatat aagaaaggat ttagtatttc ccttgaatgc
    44941 tgaatccttt tttacatttg taaagaaaga ttctaaatgt acggaccccc aaaagttgga
    45001 gtctcttttt gtcagaatag agaaaatttt tgttaatttt acttgtttcc tattgctttc
    45061 tcagttatta tttgttatat taaaagtata attatttttt atttatcagg gttaagcatt
    45121 gcactttcag aggaaggagt attttttaaa aagaaaatgt aaacgcttgc tcaaaaatga
    45181 aaggatttag aagtttatga ataaaggatt atttgaaaaa cgttgtaaat atagtattcg
    45241 gaaattttca ttaggtgttg cttctgttat gattggagct gcattctttg ggacaagtcc
    45301 ggttcttgca gatagcgtgc agtctggttc cacggcgaac ttaccagctg atttagctac
    45361 tgctcttgca acagcaaaag agaatgatgg gcgtgatttt gaagcgccta aggtgggaga
    45421 agaccaaggt tctccagaag ttacagatgg acctaagaca gaagaagaac tattagcact
    45481 tgaaaaagaa aaaccggctg aagaaaaacc aaaagaggat aaacctgcag ctgctaaacc
    45541 tgaaacgcct aagacggtaa cccctgaatg gcaaacggta gagaaaaaag aacaacaggg
    45601 aacagtcact atccgagaag aaaaaggtgt ccgctacaac caactatcct caactgctca
    45661 aaatgataac gcaggtaaac cagctctgtt tgaaaagaag ggcttgaccg ttgatgccaa
    45721 tggaaatgca actgttgatt taaccttcaa agaagattct gaaaagggca aatcacgctt
    45781 tggtgtcttc ttgaaattta aagataccaa taataatgtt tttgtcggtt atgacaagga
    45841 tggctggttc tgggagtata aatctccaac aactagcact tggtatagag gtagtcgtgt
    45901 tgctgctcct gaaacaggat caacaaaccg tctctctatc actctcaagt cagacggtca
    45961 gctaaatgcc agcaataacg atgtcaatct ctttgacaca gtgactctac cagctgcggt
    46021 caatgaccat cttaaaaatg agaagaagat tcttctcaag gcgggctctt atgacgatga
    46081 gcgaacagtt gttagcgtta aaacggataa ccaagagagg gtaaaaacag aggatacccc
    46141 tgcccagaaa gaaacaggtc cggttgttga cgatagcaag gtgacttatg atacgatcca
    46201 gtctaaggta cttaaggcag taattgacca agccttccct cgtgtcaagg aatacacctt
    46261 gaatggacat actttgccag gacaggtgca acaattcaac caagtcttta tcaataacca
    46321 ccgaatcacc cctgaagtca cttataaaaa aatcaatgag acaacagcag agtacttgat
    46381 gaagcttcgc gatgatgctc acttaatcaa tgcggaaatg acagtacgct tgcaagttgt
    46441 ggacaatcaa ttgcactttg atgtgaccaa gattgtcaac cacaatcaag tcactccagg
    46501 tcaaaagatt gatgacgaaa gaaaactact ttcttctatt agtttcctcg gcaatgcttt
    46561 agtctctgtt tctagtgatc aaactggtgc taagtttgat ggggcaacca tgtcaaacaa
    46621 tacgcatgtc agcggagatg atcatatcga tgtaaccaat ccaatgaagg atttggctaa
    46681 gggttacatg tatggatttg tttctacaga taagcttgct gctggtgttt ggagtaactc
    46741 tcaaaatagc tatggtggtg gttcgaatga ctggactcgt ttgacagctt ataaagaaac
    46801 agtcggaaat gccaactatg taggaatcca cagctctgaa tggcaatggg aaaaagctta
    46861 taagggcatt gttttcccag aatacacgaa ggaacttcca agtgctaagg ttgttatcac
    46921 tgaagatgcc aatgcagaca agaaagttga ttggcaagat ggtgccattg cttatcgtag
    46981 cattatgaac aaccctcaag gttgggaaaa agttaaggat atcacagctt accgtatcgc
    47041 gatgaacttt ggttctcaag cacaaaaccc attccttatg accttggatg gtatcaagaa
    47101 aatcaatctc cacacagatg gtcttgggca aggtgttctc cttaaaggat atggtagcga
    47161 aggccatgac tctggtcact tgaactatgc tgatattggt aagcgtatcg gtggtgtcga
    47221 agacttcaag accctaattg agaaggctaa gaaatatgga gctcatctag gtatccacgt
    47281 taacgcttca gaaacttatc ctgagtctaa atacttcaat gaaaaaattc tccgtaagaa
    47341 tccagatgga agctatagct atggttggaa ctggctagat caaggtatca acattgatgc
    47401 tgcctatgac ctagctcatg gtcgtttggc acgttgggaa gatttgaaga aaaaacttgg
    47461 tgacggtctc gactttatct atgtggacgt ttggggtaat ggtcaatcag gtgataacgg
    47521 tgcctgggct acccacgttc ttgccaaaga aattaacaaa caaggctggc gctttgcgat
    47581 cgagtggggc catggtggtg agtacgactc taccttccat cactgggcag ctgacttgac
    47641 ctacggtggc tacaccaata aaggtatcaa cagtgccatc acccgcttta tccgtaacca
    47701 ccaaaaagat gcttgggttg gggactacag aagttatggt ggtgcagcca actatccact
    47761 gctaggtggc tacagcatga aagactttga aggctggcaa ggacggagcg actacaatgg
    47821 ctacgtgact aacctctttg cccatgatgt catgaccaag tatttccaac acttcactgt
    47881 aagtaaatgg gaaaatggta caccggtgac tatgaccgat aacggtagca cctataaatg
    47941 gactccagaa atgcgagtgg aattggtaga tgctgacaat aataaagtag ttgtaactcg
    48001 taagtcaaat gatgtcaata gcccacaata tcgcgaacgt acagtaactc tcaacggacg
    48061 tgtcatccaa gatggttcag cttacttgac tccttggaac tgggatgcaa atggtaagaa
    48121 actttctact gagaaggaaa agatgtacta cttcaatacg caggccggtg caacaacttg
    48181 gacccttcca agcgattggg caaagagcaa ggtttacctt tacaagctaa ctgaccaagg
    48241 taagacagaa gagcaagaac taactgtaaa agatggtaaa attaccctag atcttctagc
    48301 aaatcaacca tacgttctct atcgttcaaa acaaaccaat cctgaaatgt catggagtga
    48361 aggcatgcac atctatgacc aaggatttaa cagtggtacc ttgaaacatt ggaccatttc
    48421 aggcgatgct tctaaggcag aaattgtcaa gtctcaaggg gcaaacgata tgcttcgtat
    48481 tcaaggaaac aaagaaaaag ttagtctcac tcagaaatta actggcttga aaccaaatac
    48541 caagtatgcc gtttatgtcg gtgtcgataa ccgtagtaat gccaaggcga gcatcactgt
    48601 aaatactggt gaaaaagaag tgactactta taccaataag tctctcgcgc tcaactatgt
    48661 taaggcttac gcccacaata cacgtcgtga caatgctaca gttaacgata caagttactt
    48721 ccaaaacatg tacgccttct ttacaacagg atcggacgtc tcaaatgtta ctctgacatt
    48781 gagtcgtgaa gctggtgatc aagcaactta ctttgatgaa attcgtacct ttgaaaacaa
    48841 ttcaagcatg tatggagaca agcatgatac aggtaaaggc accttcaagc aagactttga
    48901 aaatgttgct cagggtatct tcccatttgt agtgggtggt gttgaaggtg ttgaagataa
    48961 ccgcactcac ttgtctgaaa aacactatcc atatacacaa cgtggttgga atggtaagaa
    49021 agtcgatgat gttatcgaag gaaattggtc actcaagaca aatggactag tgagccgtcg
    49081 taacttggtt taccaaacta ttccgcaaaa cttccgtttt gaagcaggta agacctaccg
    49141 tgtaaccttt gaatacgaag taggttcaga caatacatat gcttttgtag tcggtaaggg
    49201 agaattccag tcaggtcgtc gtggcactca agcaagcaac ttggaaatgc atgaattgcc
    49261 aaatacttgg acagattcta agaaagccaa gaaggcaacc ttccttgtga caggtgcaga
    49321 aacaggggat acttgggtag gtatctactc aactggcaat gcaagtaata ctcgtggtga
    49381 ttctggtgga aatgccaact tccgtggtta taacgacttc atgatggata atcttcaaat
    49441 cgaagaaatt accctaacag gtaagatgtt gacagaaaat gctctgaaga actacttgcc
    49501 aacggttgcc atgactaact acaccaaaga gtctatggat gctttgaaag aggcggtctt
    49561 taacctcagt caggccgatg atgatatcag tgtggaagaa gcgcgtgcag agattgccaa
    49621 gattgaagcc ttgaagaatg ctttggttca gaagaaaacg tctttggtag cagatgactt
    49681 tgcaagtctt acagctcctg ctcaggctca agaaggtctt gcaaatgcct ttgatggaaa
    49741 cttatctagt ttatggcata catcatgggg cggaggagat gtaggcaagc ctgcaaccat
    49801 ggtcttgaaa gaaccaactg aaatcactgg acttcgttat gttccacgtg gatcaggttc
    49861 aaatggtaac ttgcgtgatg tgaaacttgt tgtgacagat gagtctggca aggagcatac
    49921 ctttactaca actgattggc cagataacaa taagtcaaaa gatattgact ttggtaagac
    49981 aatcaaggct aagaaaattg tccttactgg taccaagaca tacggagatg gtggagataa
    50041 ataccaatct gcagcggaac ttatctttac tcgtccacag gtagcagaaa cacctcttga
    50101 cttgtcaggc tatgaagcag ctttggctaa ggctcagaaa ttaacagaca aagacaatca
    50161 agaggaagta gctagcgttc aggcaagcat gaaatatgcg acggataacc atctcttgac
    50221 ggaaagaatg gtggaatact ttgcagatta tctcaaccaa ttaaaagatt ctgctacgaa
    50281 accagatgct ccaactgtag agaaacctga gtttaaactt agctctttag cttccgatca
    50341 aggtaagacg ccagattata agcaagaaat agatagacca gaaacacctg aacaaatctt
    50401 gccagcaaca ggtgagagtc aatctgacac agccctcttc ctagcaggtg ttagcctagc
    50461 cctatctgct ctctttgtag taaaaacgaa gaaagactag tatttagtaa aacctcttaa
    50521 caagattacg gaagcagtct ctatcttttc caatgaggtt tatagtacag aaaaagtctg
    50581 agaagatgtc ttctcagact tttgttaagc acataaatac aatagtgcta tgacaaaatc
    50641 acccagaaaa tctgggtgat aaatgttatg gttgtgctgg ttgaggattc tgattttgtt
    50701 gatcaggggt tgtatttgat tgttgcgtat tattgttagg attggtagtc gtactattat
    50761 ttgtgcttgg agtggttgag ctagactgtg aagttgaact atctgatgat gagcttgaac
    50821 tttcagttga tgggggttgt tgtggagcag gtgagttcca cgtagaacga gcaccatttt
    50881 taaatacgaa ttctccattt ctgtagagcc cctctggtat attccaatcc tctggattgc
    50941 ttccttcaga caggtaggtc atcatagagc ggtaaacttt ggcagcgacc gtaaggccat
    51001 tgcctacaag tggtgtcaga cggttagaat agcctgtcca tacagccatt gaatatttac
    51061 gcgtatagcc agcaaatagt tcgtcaggtg ctacaaattg agaggtcttg atgtggtttt
    51121 caatttcctc gtctgtatag ttagaggttc ctgttttacc agcctgaggg agccaagcaa
    51181 gataggcatt tcgtccagtt ccataactca agactgtttt catcatgtcg gtcatcatat
    51241 aggctgtcgt ttccttcatg gcacgagttc cgacattaga gaactctttt tcactcccat
    51301 cactaaagac gactttatgg atatacattg gtttatagta agttccacca tttgcaaagg
    51361 cagcgtaagc agcagccatc ttttcactac ttgctccata ttttttgtct gattcggttg
    51421 tgttacttga aatggcattt gagtagtgaa tacttgggta gtcgattcct agaccattta
    51481 ggaaagtctt ggcgcggttg agtccgacct tgtttagagt ttccacggct gggacgtttc
    51541 gcgattgttg cagggcgtat tgcaaggtga tgttgccaaa gtagccccta tcccagttat
    51601 aaacaggagt atttgtccca gggtagttat agggctcatc gtgaacgata gtagcagttg
    51661 aatcgtagac accgtactcc aaggcaggag catagtctgt gatcggtttc atagttgatc
    51721 cccagtcgcg gtttgtttct actgcttggt taattccgaa ggaaacatta cttgactgat
    51781 ggcgtgctcc tagctgggca atgactttac cgttagaaac atcaacaatg gtagaagcga
    51841 cttgcaattc atcgtctgga taggcaacgt attcgtctgt attgtaaata tcccacagat
    51901 gtttttgagc ttcttggtct acatttgtgt agacatccat cccagttgtg agcaggttat
    51961 agcctgtttc ttcttcaact tgattgatga cttccttgag gtaattatcc atgtaagcag
    52021 ggtaattact tgctgatttg agactttgta gtccatcagt aattggtgta ttgactgctt
    52081 tctcatactg ttcagcagag atgtagcctt gatttttcat ttcagataag accaagtttc
    52141 ggcggtcttg ggctgcttct ggatgtgaat aggggtcata ttggtttggt gcctgaggca
    52201 ttccagccag caaggctaac tgaggtaaac ttaaattatt gaggtcttta ccatagtagt
    52261 tttgagctgc tgtctgcatt ccatagttcc cattagacat gtagacctta tttatatagt
    52321 aggtcaagat ttcttgcttg gttgcttttt gttctaactg aatcgctaac caagcttcct
    52381 gagccttacg agaaatagtc tggtcggaag tcgaagttga aaagtaagtc aacttaatca
    52441 actgttgagt gagagttgat ccaccttgga gggaattgct ttgcagattg cgcaagaaag
    52501 ctcccaggat acggatggta tcaatccccc tgtggtcgaa gaagcgatgg tcttcgatag
    52561 aaacgattgc cttaaccaaa tctgtgggaa tatcattagc ttgggcattg acgcggcgtt
    52621 cagaacccaa gtcagcaatg agttgatttt tattgtcgta gattttacta gaagttgttg
    52681 caactagttt actctcggat aggctaggag ccttgctaac gtagtagaaa aaaactcctc
    52741 cgcctaagac aatggctgcg ataaccaagc ttaagaagct aatgctcaga tacttgatta
    52801 ggcgcagaat cgttggtttg ttcatcttgt tttaccacct aataaatgtt ctttgataac
    52861 attgagataa ggaatttgag ggaaggcacc agccttgatt tcatatccat attctcgaat
    52921 atattcaagt ggcattgatt tttgtccctt atcttgatga tagaagcgaa tcaaatcgaa
    52981 tgccagcaat aagtaggttt cttgctgaga agaaaagtga agaaggacaa agcagattcc
    53041 ttgttgggca aggacttgtt ccatatgctg aatctgatgt ggatgaaaat ttttcatcgg
    53101 aatcgcacgt ttttgttttg tttccttgac ttcaaagtcg atgtaatatc cattataaac
    53161 gccagaatag tccgtcgttg aagcttgtcg aaaataggct tcaacaatct tggcacgact
    53221 tcgttgtgga tagtccactt gtacgatttg aataggagtt ggtttcttat gtataacagc
    53281 caagccctga gacaaatagt agtcgttggt agcattgatc atcttttcaa aagacattcc
    53341 tcgatttgcg aaatttttgg gttgagaaag agatgtttgt cttttttgtg gtgaaacttt
    53401 atgtggatag ttgaccataa ttctccttat tggtacaata acatcacttt attataccat
    53461 aatttgcaca gaaagggtta aaaatggcta cagctttggt tttaggctat tctgcttttg
    53521 atttgggttt attttctgat aaggatcctc gtcttaaatt gattaaaaaa gcgatacgta
    53581 aagatttaga ggctatggca gcagatgggg tgtcttggct tgtgtttaca gggagtttgg
    53641 gttttgaata ttgggtttta gaggttgctc aggagatgaa aaccgaatac ggtttccagt
    53701 tggccaccat ttttgctttt gaaacccatg gggaaaattg gaatgaaggc aatcagatga
    53761 aactgagtcg ctttaagcag gtagactttg tcaaatatgc ctatcctcgc tatgaacaca
    53821 aggggcagtt aagagattac cagcagtttt tgctggaaaa cacgactagt tcctatcttt
    53881 tttatgatga agaaaatgaa acaaaactag cttattttta ccaaaagatg aaaaatcaag
    53941 aggactattt tataaagaga ttaacatttg atcaattaaa tgaacttgct gaaaattttt
    54001 ccgaaaattg aagctttgac cttgattttt gtttgccttt ttttatataa taatactagc
    54061 aagcgagaat ggagagagac atggcaagta ttattttttc agcgaaagat atttttgaac
    54121 aagagtttgg acgtgaagtc cgtggctata ataaagtaga agttgacgag tttttagacg
    54181 atgtcatcaa ggactatgaa acctatgctg ccttggtcaa gtcacttcgt caggaaattg
    54241 cggatttgaa ggaagaatta actcgtaaac cgaaaccttc accagttcaa gcagaacccc
    54301 ttgaagcggc aattacaagt tctatgacga attttgatat tttgaaacgc ctgaatagat
    54361 tggaaaaaga agtttttggt aaacaaattt tagataactc agatttttaa gtagttattt
    54421 gagatgtgca atttttggat aatcgcgtga ggagaattgc ttctcatgag gaaagtccat
    54481 gctagcacag gctgtgatgc ctgtagtgtt tgtgctaggc gaaaccataa gcctagggac
    54541 gagaaatcgt tacggcagtt gaaatggcta agtccttgga taagccagag taggcttgaa
    54601 agtgccacag tgacggagtc tttctggaaa cagagagagt ggaacgcggt aaacccctca
    54661 agctagcaac ccaaattttg gtcggggcat ggagtacgcg gaaacgaacg tagtattctg
    54721 actgctatca gctagagctg ttagtggtag acagatgatt atcgaaggaa gtggtcctag
    54781 tcacttctgg aacaaaacat ggcttataga aaattgcata taggttgggg ctgagaaatt
    54841 ttctcaacct cattttttaa agtggacata tagaaaggtc ttgcaagact gtaacatgaa
    54901 aaaagaattt aatttaattg caactgtggc agcagggctt gaggctgtcg ttggtcgtga
    54961 agtgcgagag ttgggctacg attgtcaggt tgaaaatgga cgtgttcgtt ttcaaggaga
    55021 cgtgagagct attatcgaaa ccaacctttg gcttcgggca gcagatcgta tcaaaattat
    55081 cgtaggaacg ttcccagcta agacttttga agagctattt cagggagttt tcgctttaga
    55141 ttgggaaaat tatttaccac ttggagctcg gttcccgatt tcaaaagcta aatgtgttaa
    55201 gtccaaactt cacaatgagc ccagtgttca ggctatttct aagaaagctg ttgtcaagaa
    55261 attgcagaaa cactatgctc gcccagaagg ggttcctctg atggagaatg gtccagagtt
    55321 taagattgag gtctctattc tcaaagatgt ggcaactgtc atgattgata cgaccgggtc
    55381 tagcctcttt aaacgtggtt atcgtaccga aaaaggtggc gctcctatca aggaaaatat
    55441 ggcagcagcc attttacaac tttctaactg gtatccagac aagcctttga ttgatccgac
    55501 ctgtggttcg gggactttct gtattgaggc agttatgatt gctagaaaga tggcgccagg
    55561 tcttcgtcgc tcttttgcat ttgaggaatg gaactggatc agcgatcgct tgattcaaga
    55621 agtgcgcaca gaagcggcta aaaaagtaga acgtaagctt gagttggata tcatgggctg
    55681 tgatattgat gctcgcatgg tggaaattgc taaggccaat gctcaggcag ctggtgttgc
    55741 aggagatatt acttttaagc agatgcgcgt gcaggattta cgttccgata aaatcaatgg
    55801 agtaatcatt tccaatccgc cttatggtga acgtttgtca gatgatgcag gggtgaccaa
    55861 gctctatgct gagatggggc aagtatttgc accgctgaaa acttggagca aatttatcct
    55921 gactagtgat gaagcttttg aaagcaagta tggtagccaa gcagataaga agcgtaagtt
    55981 atacaacgga accttgaaag tggatctata tcaatatttt ggtcagcgtg tcaaacggca
    56041 agaggtaaaa tagaaaggga tactcatgag taaaaaaaga cgaaatcgtc ataaaaaaga
    56101 aggtcaagaa ccgcaatttg attttgatga agcaaaagag ctaacagttg gtcaagctat
    56161 tcgtaaaaat gaagaagtgg aagcaggagt cttgcctgag gattccattt tggacaagta
    56221 tgttaagcaa cacagagatg aaattgaggc ggataagttt gcgactcgtc aatacaaaaa
    56281 agaggagttc gttgaaactc agagtctgga tgatttaatt caagagatgc gtgaggctgt
    56341 agagaagtca gaagcttctt cggaggaagt tccatcttct gaagacatct tactaccctt
    56401 gcctctggac gatgaggagc aaggcttgga tcctctattg ctagatgatg aaaatccaac
    56461 agaaatgact gaagaagtgg aagaggagca aaacctttct cgtctggatc aagaggactc
    56521 agaaaagaaa agtaaaaaag gctttatttt gaccgttttg gcgcttgtat cagtaattat
    56581 ttgtgtcagt gcttattatg tctaccgtca agtggctcgt tcgaccaagg aaattgaaac
    56641 ttctcaatca actacagcca atcaatcgga tgtggatgat tttaatacac tttatgacgc
    56701 cttttacaca gatagcaata aaacggcttt gaaaaatagc cagtttgata aactgagtca
    56761 actcaaaacc ttgcttgata aactggaagg tagtcgtgaa catacgcttg ccaaatctaa
    56821 atatgatagt ctagcaacgc aaatcaaggc tattcaagat gtcaatgcac aatttgaaaa
    56881 atcagctatt gtggatggtg tgttggatac caatgccaaa gccaaatcgg atgctaaatt
    56941 tacagatatt aaaactggaa atacggagct tgataaagtg ctagataagg ctatcagtct
    57001 tggtaagagc cagcaaacaa gtacttctag ctcaagttta agtcaaacta gcagctcaag
    57061 ttcaagtcaa gcaagttcaa atacgactag tgagccaaaa ccaagtagtt caaatgagac
    57121 tagaagtagt cgcagtgaag tcaatatggg tctctcgagt gcaggggttg ctgttcaaag
    57181 aagtgccagt cgtgttgcct ataatcagtc tgctattgat gatagtaata actctgcctg
    57241 ggattttgcg gatggtgtct tggaacaaat tctagcgact tcacgttcac gtggctatat
    57301 cactggagac caatatatcc ttgaacgtgt caatatcgtt aacggcaatg gttattataa
    57361 cctctataag ccagatggaa cctatctctt tacccttaac tgtaagacag gctactttgt
    57421 cggaaatggc gctggtcatg cggatgactt ggactactaa gcagtcgtta caaaattctt
    57481 tcttttcaaa agtaaaaatg ataaaataaa acaaatgaaa caagaggagt gtcaaatgac
    57541 aaaagctaac tttggtgtcg taggtatggc cgtaatgggt cgtaaccttg cccttaatat
    57601 tgaatcacgt ggttacacag ttgctatcta caaccgtagt aaagaaaaaa cggaagatgt
    57661 gattgcttgc catcctgaaa agaactttgt accaagctat gacgttgaaa gttttgtaaa
    57721 ctcaatcgaa aaacctcgtc gtatcatgct gatggttcaa gctggacctg gtacagatgc
    57781 tactatccaa gcccttcttc cacaccttga caagggtgat atcttgattg acggtggaaa
    57841 tactttctac aaagatacca tccgtcgtaa tgaagaattg gcaaactcag gtatcaactt
    57901 tatcggtact ggagtttctg gtggtgaaaa aggtgccctt gaaggtcctt ctatcatgcc
    57961 tggtggacaa aaagaggcct acgaattggt tgcggatgtt cttgaagaaa tctcagctaa
    58021 agcaccagaa gatggcaagc catgtgtgac ttacatcggt cctgatggag ctggtcacta
    58081 tgtgaaaatg gttcacaatg gtattgagta cggtgatatg caattgatcg cagaaagcta
    58141 tgacttgatg caacacttgc taggcctttc tgcagaggat atggctgaaa tctttactga
    58201 gtggaacaag ggtgaattag acagctactt gatcgaaatc acagctgata tcttgagccg
    58261 taaagacgat gaaggccaag atggaccaat cgtagactac atccttgatg ctgcaggtaa
    58321 caagggaact ggtaaatgga cgagccaatc atctcttgac cttggtgtac cattgtcact
    58381 gattactgag tcagtgtttg cacgctacat ttcaacttac aaagaagaac gtgtacatgc
    58441 tagcaaggtg cttccaaaac cagctgcctt caactttgaa ggagacaagg ctgaattgat
    58501 tgaaaaaatc cgtcaagccc tttacttctc aaaaatcatt tcatacgcac aaggatttgc
    58561 tcaattgcgt gtagcctcta aagaaaacaa ctggaacttg ccatttgcag atatcgcatc
    58621 tatctggcgt gatggctgta tcatccgttc tcgtttcttg caaaagatta cagatgctta
    58681 caaccgcgat gcagatcttg ccaaccttct tttggacgag tacttcttgg atgttactgc
    58741 taagtaccaa caagcagtac gtgatatcgt agctcttgcg gttcaagcag gtgtgccagt
    58801 gccaactttc tcagcagcta ttacttactt tgatagctac cgttcagctg accttccagc
    58861 taacttgatc caagcacaac gtgactactt tggtgctcac acttaccaac gtaaagacaa
    58921 agaaggaacc ttccactact cttggtatga cgaaaaataa gtaggtcagc catggggaaa
    58981 cggattttat tacttgagaa agaacgaaat ctagctcatt ttttaagttt ggaactccag
    59041 aaagagcagt atcgggttga tctggtagag gaggggcaaa aagccctctc catggctctt
    59101 cagacagact atgatttgat tttattgaat gttaatctgg gagatatgat ggctcaggat
    59161 tttgcagaaa aattgagccg aactaaacct gcctcagtca tcatgatttt agatcattgg
    59221 gaagacttgc aagaagagct ggaagttgtt cagcgttttg cagtttcata catctataag
    59281 ccagtcctta tcgaaaatct ggtagcgcgt atttcggcga tcttccgagg tcgggacttc
    59341 attgatcaac actgcagtct gatgaaagtt ccaaggacct accgcaatct taggatagat
    59401 gttgaacatc acacggttta tcgtggtgaa gagatgattg ctctgacccg ccgtgagtat
    59461 gaccttttgg cgacacttat gggaagcaag aaagtattga ctcgtgagca attgttggaa
    59521 agtgtttgga agtatgaaag tgcgaccgag acaaatatcg tagatgtcta tatccgctat
    59581 ctacggagca agcttgatgt taaaggccaa aaaagctaca ttaaaactgt gcgtggtgtt
    59641 ggatatacca tgcaagaata gaaaagcagt tgcagttgtg taactgcttt tttgaggagt
    59701 ttttatatat tgacatacaa tctagttttt actacaatcg ttttaggagg atatataaaa
    59761 tgaagctttt gaaaaaaatg atgcaagtcg cattagcagt ctttttcttt ggtttgctag
    59821 ctacaaatac ggtatttgcg aataccacag gtggccgatt tgttgataag gataatagaa
    59881 aatattatgt aaaagatgat cataaagcaa tctattggca taaaatagac ggtaaaactt
    59941 actattttgg tgatattgga gagatggttg tcggttggca atacttagaa attcctggaa
    60001 caggttatcg tgataattta ttcgataacc aaccagttaa tgaaattggc cttcaggaga
    60061 agtggtacta ttttggacaa gatggtgctt tgctagaaca aacagataaa caagtactag
    60121 aggcaaaaac gtctgaaaat acaggaaaag tatacggtga acaatattct ctatctgctg
    60181 aaaagagaac ttattatttt gataataatt atgctgtaaa gacaggctgg atttatgaag
    60241 agggtcattg gtattattta aataagctag gaaattttgg cgatgattct tacaatccac
    60301 taccaattgg tgaagttgct aagggttgga ctcaagattt tcatgttact attgacattg
    60361 atagaagcaa acctgctcca tggtactacc tagatgcttc aggtaagatg cttacagatt
    60421 ggcaaaaagt aaacggaaaa tggtattatt ttggctcctc tggttctatg gcaacaggtt
    60481 ggaaatatgt acgaggcaaa tggtattact tagataataa aaatggtgat atgaaaacag
    60541 gatggcaata ccttggtaac aagtggtact acctccgttc atcaggagct atggtaactg
    60601 gctggtatca agatggttca acttggtact atttagatgc tgaaaatggt gatatgaaaa
    60661 taggttggac aaaagtaaat ggaaaatggt attatctcaa ttcctctgga gcaatggtta
    60721 caggtagtca aactatcgat ggtaaagttt ataacttcgc ttcatctggt gagtggattt
    60781 aatgttggag gatatataaa atgaagcttt tgaaaaaaac tatgcaagct ggactaacag
    60841 taattttctt tggtttgcta gctacgaata cagtatttgc agataactct gaaggatggc
    60901 agtttgtcca agaaaacggt agaacctatt acaaaaaggg ggacctcaaa gaaacctact
    60961 ggcgagtgat tgatggtaag tactattatt ttgattctct atctggagag atggttgtcg
    61021 gctggcaata tatcccgttt ccatctaaag gtagtacaat tggtccttac ccaaatggta
    61081 tgagattaga aggttttcca aattcagagt ggtactactt cgataaaaat ggagtgctac
    61141 aagagtttgt tggttggaaa acattagaga ttaaaactaa agacagtgtt ggaagaaagt
    61201 acggggaaaa acgtgaagat tcagaagata aagaagagaa acgttattat acgaactatt
    61261 actttaatca aaatcattct ttagagacag gttggcttta tgatcagtct aactggtatt
    61321 atctagctaa gacggaaatt aatggagaaa actaccttgg tggtgaaaga cgtgcggggt
    61381 ggataaacga tgatttgact tggtactatt tagatccaac aactggtatt atgcaaacag
    61441 gttggcaata tctaggtaat aagtggtact acctccgttc atcaggagca atggccactg
    61501 gctggtatca ggaaggtacc acttggtatt atttagacca gccaaatggc gatatgaaaa
    61561 caggttggca aaaccttggg aacaaatggt actatctccg ttcatcagga gcaatggcaa
    61621 ctggttggta tcaagatggt tcaacttggt actacctaaa tgcaggtaat ggagatatga
    61681 agacaggttg gttccaggtc aatggcaact ggtactatgc ttatagctca ggtgctttgg
    61741 cagtgaatac gaccgtagat ggctattctg tcaactataa tggcgaatgg gttcggtaat
    61801 gacagggcgc ttataattat attagaacac tcgcttaatc aaagaagtga ctttgttgta
    61861 cttgacctga cgattgggga gattaaaagc atgtgaaatc tacacatgct ttttcgttag
    61921 ttatgagtgt tgaacttgac taaccattga caaaagataa gagcaattaa aataagatac
    61981 aaaaatatca atgctaactg caccgaaacg cccgatgcta tggatagggc taatagggag
    62041 agcagggacg gggcgagaat gtccactgtg ctcagagcag agcccaccgt ccccatcttg
    62101 tcactgggga tatgggcaaa gacagctgct tgtaggcgag ggctgagaat gccgataatc
    62161 gtagaactga tgaaactggt catgaaaatt acgatatagg cttgacaaag gatactagtt
    62221 attagagtca atagggaaat ctcacagaaa accaagaggt gcgtgaaacg gatattttta
    62281 aatagattac tgctggtcat attgccaagg atagctccac aagacatgat gatggagagc
    62341 agggcgagga tttgcccaat gctcagttgt gctagtgtct gttggatgaa gcggagggca
    62401 atcagccgag gggacacatc caagatggca atcatactgg tcgtcagaaa cagtagtatg
    62461 acggtatctt ttaacctcag gagcacagcc agcgactgtt taagatgttg aaaatatttc
    62521 ttaaaactca gtgctgtatg tgacatttca attctttttt caacctcata caaggtatgt
    62581 cgaataacat acaggcccaa aaaggcaatg acaaaagtca gagtgttgat aagggaaata
    62641 gtttgaatac ttataacatt gataaggaat gcgccagcca gattggcgac aatacggaca
    62701 accctcatca gagactgcct gaaccccatg gcatcatgca ggtcgtcctt aattacactg
    62761 atgtagaggg cgttcatcat gtaggcagac aggtagctca aggtgtcaga gatgaggttg
    62821 atgatgacaa tcataatgac tgaaactaat gaaaagggcg acaagacgag aaatactgtc
    62881 aaaatagcgt agagcaggat tttgattttg gcaatccaga gtgcgtgttt gactctattt
    62941 tcttgaaaat ctcctagaat cccgagaaag agttgcgata gtaggggaac catctctgaa
    63001 atggaaatca gtaaaatcgc tagcggagcg aaattgtact gagccacata attgataatg
    63061 gcgaggtaga aaatactgtc gccgaatgat gaaaaacagc tgtttagcag caactgtcta
    63121 tatatgttgt ttgtccaaaa taatttcata cttttctcct tatgtctgca catcgaatgg
    63181 gaatttatta tttaatagac accaatatac cccatgcttc ctattccgaa gtcaaacaaa
    63241 tctgctttac cactatctcc ttgaaacatc agtaaaccgt gatcatctcg ttcagaacat
    63301 gctaaaatta cctgttggat ttttttcatc agtaatttgt tttgattgta gacagtggtt
    63361 tgtagtaagc tagttattcc gtggcaatat cctgtcatca tttttagatg atggttaaaa
    63421 acaaattctt gatatttact aataatatct ttgtttccgt cacaatcgta catacaaaga
    63481 tataagatta ttccggaaat tcctttgcac caagaaagtt gtaaatttcc taaattttca
    63541 gtattagaag taactttttc taataatttt tttaattcag tatggaatgt atggagatca
    63601 ttatagaaca tagaaggttc taagacttta gaataggcaa ataaagcata tgcaattcca
    63661 caatatccat gagcaaagct atagtctaaa atgctttctt tggctgtatc tctttgtagg
    63721 aaataatgat aaatttcccc tatactattg tggatgaaaa ttttaagagt attgtcattg
    63781 gtaaattgat agtattttat taatgataat aggacaccag attttcccaa tgcaaagtct
    63841 atttcctcta gagtatcata attctctatt aattttttag cggtgacgtt tgctaattgt
    63901 agatagtatt gatttttact gatagaaaat aaatgtagga gtaaccatag atagcctgca
    63961 tcaccaaata gcagtgagta ttgatattca tatgtatgtg tcgttctaat tgtcactgcc
    64021 ttcttgatga tagagagtat tttagaatcc agttctgggg ggtacaattt atttagagga
    64081 aacagtagtc cagctattcc gtgttggaat gataaattac ttacgaaatt tccaaattct
    64141 gttgaagaag tgatccttcc ttcagaattt acagttttat ctagtaaaaa ttgtagaaca
    64201 ctattacatt ctgttttgta atcatattta tgttcctcta tttttttaat tttgactaaa
    64261 ttatttgttt gacttaaatt tagtagacat tgtaaccaaa atagttgctc atctgtgagc
    64321 tgaccttgag tatgtgatag ttctagtaat tgaataggat cctttagtta gattcaatca
    64381 atctataaca caacaacata ataatacttt taggataact tatcaaatat tatagtaaaa
//
LOCUS       DAVKBC010000007        54475 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVKBC010000007 DAVKBC010000000
VERSION     DAVKBC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54475
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.007"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            178..1659
                     /locus_tag="VWX64_000509"
     CDS             178..1659
                     /locus_tag="VWX64_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9190043.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2021..3022
                     /locus_tag="VWX64_000510"
     CDS             2021..3022
                     /locus_tag="VWX64_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9190044.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3172..4089
                     /locus_tag="VWX64_000511"
     CDS             3172..4089
                     /locus_tag="VWX64_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9190045.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4100..4990
                     /locus_tag="VWX64_000512"
     CDS             4100..4990
                     /locus_tag="VWX64_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9190046.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNIPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVETAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5019..6635
                     /locus_tag="VWX64_000513"
     CDS             5019..6635
                     /locus_tag="VWX64_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9190047.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNVNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6645..7964
                     /locus_tag="VWX64_000514"
     CDS             6645..7964
                     /locus_tag="VWX64_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9190048.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMVFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8172..8244)
                     /locus_tag="VWX64_000515"
     tRNA            complement(8172..8244)
                     /locus_tag="VWX64_000515"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8209..8211),aa:Lys,seq:ctt)
     gene            complement(8509..9780)
                     /locus_tag="VWX64_000516"
     CDS             complement(8509..9780)
                     /locus_tag="VWX64_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU9190049.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFNFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10050..10289
                     /locus_tag="VWX64_000517"
     CDS             10050..10289
                     /locus_tag="VWX64_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190050.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10454..10633
                     /locus_tag="VWX64_000518"
     CDS             10454..10633
                     /locus_tag="VWX64_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190051.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10770..10949
                     /locus_tag="VWX64_000519"
     CDS             10770..10949
                     /locus_tag="VWX64_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU9190052.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            10986..11438
                     /locus_tag="VWX64_000520"
     CDS             10986..11438
                     /locus_tag="VWX64_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU9190053.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11729..12199
                     /locus_tag="VWX64_000521"
     CDS             11729..12199
                     /locus_tag="VWX64_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU9190054.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     SLFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12218..13321
                     /locus_tag="VWX64_000522"
     CDS             12218..13321
                     /locus_tag="VWX64_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU9190055.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERATTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNFWFPRL"
     gene            13287..13715
                     /locus_tag="VWX64_000523"
     CDS             13287..13715
                     /locus_tag="VWX64_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9190056.1"
                     /translation="MELEISGFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            13853..14803
                     /locus_tag="VWX64_000524"
     CDS             13853..14803
                     /locus_tag="VWX64_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU9190057.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGEVKMGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            14805..15548
                     /locus_tag="VWX64_000525"
     CDS             14805..15548
                     /locus_tag="VWX64_000525"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU9190058.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15559..17355
                     /gene="pepF"
                     /locus_tag="VWX64_000526"
     CDS             15559..17355
                     /gene="pepF"
                     /locus_tag="VWX64_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9190059.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNNPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            17602..18156
                     /locus_tag="VWX64_000527"
     CDS             17602..18156
                     /locus_tag="VWX64_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU9190060.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTDFSSQYGWVHAFAHGADLLTEVVCHPDFPINRIHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDDLKEAIQSFQY"
     gene            18267..18935
                     /locus_tag="VWX64_000528"
     CDS             18267..18935
                     /locus_tag="VWX64_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU9190061.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(18960..19139)
                     /locus_tag="VWX64_000529"
     CDS             complement(18960..19139)
                     /locus_tag="VWX64_000529"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEU9190062.1"
                     /translation="MLKAVFEVIDKTDEVSLKHCFEVVDRTDEVSNHTYGKVKLTWFE
                     EIFEEYHTKKPCSSR"
     gene            complement(19189..19722)
                     /gene="queF"
                     /locus_tag="VWX64_000530"
     CDS             complement(19189..19722)
                     /gene="queF"
                     /locus_tag="VWX64_000530"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU9190063.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLLQHDLYPEKIDNR"
     gene            complement(20028..20342)
                     /gene="trxA"
                     /locus_tag="VWX64_000531"
     CDS             complement(20028..20342)
                     /gene="trxA"
                     /locus_tag="VWX64_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9190064.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(20359..20580)
                     /locus_tag="VWX64_000532"
     CDS             complement(20359..20580)
                     /locus_tag="VWX64_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9190065.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(20679..21059)
                     /locus_tag="VWX64_000533"
     CDS             complement(20679..21059)
                     /locus_tag="VWX64_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9190066.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(21203..22156)
                     /locus_tag="VWX64_000534"
     CDS             complement(21203..22156)
                     /locus_tag="VWX64_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9190067.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEKIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(22224..23433)
                     /gene="sstT"
                     /locus_tag="VWX64_000535"
                     /pseudo
     CDS             complement(22224..23433)
                     /gene="sstT"
                     /locus_tag="VWX64_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            23572..24132
                     /locus_tag="VWX64_000536"
     CDS             23572..24132
                     /locus_tag="VWX64_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU9190068.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            24189..25097
                     /locus_tag="VWX64_000537"
     CDS             24189..25097
                     /locus_tag="VWX64_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU9190069.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            25049..25639
                     /locus_tag="VWX64_000538"
     CDS             25049..25639
                     /locus_tag="VWX64_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU9190070.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            25642..26748
                     /gene="yqeH"
                     /locus_tag="VWX64_000539"
     CDS             25642..26748
                     /gene="yqeH"
                     /locus_tag="VWX64_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU9190071.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKFLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            26962..27273
                     /gene="yhbY"
                     /locus_tag="VWX64_000540"
     CDS             26962..27273
                     /gene="yhbY"
                     /locus_tag="VWX64_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU9190072.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            27325..27954
                     /locus_tag="VWX64_000541"
     CDS             27325..27954
                     /locus_tag="VWX64_000541"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU9190073.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GPSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            27954..28547
                     /gene="yqeK"
                     /locus_tag="VWX64_000542"
     CDS             27954..28547
                     /gene="yqeK"
                     /locus_tag="VWX64_000542"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU9190074.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            28548..29048
                     /locus_tag="VWX64_000543"
     CDS             28548..29048
                     /locus_tag="VWX64_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9190075.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            29061..29414
                     /gene="rsfS"
                     /locus_tag="VWX64_000544"
     CDS             29061..29414
                     /gene="rsfS"
                     /locus_tag="VWX64_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU9190076.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            29517..30263
                     /locus_tag="VWX64_000545"
     CDS             29517..30263
                     /locus_tag="VWX64_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9190077.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEIHEERTYELLTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            30273..31370
                     /locus_tag="VWX64_000546"
     CDS             30273..31370
                     /locus_tag="VWX64_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU9190078.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVNILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLTDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            31608..31838
                     /locus_tag="VWX64_000547"
     CDS             31608..31838
                     /locus_tag="VWX64_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEU9190079.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDKFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            32120..33733
                     /locus_tag="VWX64_000548"
     CDS             32120..33733
                     /locus_tag="VWX64_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU9190080.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            33863..34489
                     /gene="gmk"
                     /locus_tag="VWX64_000549"
     CDS             33863..34489
                     /gene="gmk"
                     /locus_tag="VWX64_000549"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU9190081.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQERLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            34514..34828
                     /locus_tag="VWX64_000550"
     CDS             34514..34828
                     /locus_tag="VWX64_000550"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU9190082.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            34894..37290
                     /locus_tag="VWX64_000551"
     CDS             34894..37290
                     /locus_tag="VWX64_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU9190083.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPMEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGIEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRARYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            37303..38238
                     /locus_tag="VWX64_000552"
     CDS             37303..38238
                     /locus_tag="VWX64_000552"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU9190084.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            38231..39544
                     /gene="rsmB"
                     /locus_tag="VWX64_000553"
     CDS             38231..39544
                     /gene="rsmB"
                     /locus_tag="VWX64_000553"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU9190085.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREDWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            39559..40299
                     /locus_tag="VWX64_000554"
     CDS             39559..40299
                     /locus_tag="VWX64_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU9190086.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            40296..42275
                     /gene="pknB"
                     /locus_tag="VWX64_000555"
     CDS             40296..42275
                     /gene="pknB"
                     /locus_tag="VWX64_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU9190087.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            42390..43148
                     /locus_tag="VWX64_000556"
     CDS             42390..43148
                     /locus_tag="VWX64_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9190088.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            43150..43599
                     /locus_tag="VWX64_000557"
     CDS             43150..43599
                     /locus_tag="VWX64_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9190089.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            43661..44285
                     /locus_tag="VWX64_000558"
                     /pseudo
     CDS             43661..44285
                     /locus_tag="VWX64_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            44353..44601
                     /locus_tag="VWX64_000559"
                     /pseudo
     CDS             44353..44601
                     /locus_tag="VWX64_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            44732..45904
                     /locus_tag="VWX64_000560"
     CDS             44732..45904
                     /locus_tag="VWX64_000560"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU9190090.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            45904..47178
                     /locus_tag="VWX64_000561"
     CDS             45904..47178
                     /locus_tag="VWX64_000561"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU9190091.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNDQEYTVPYVTEEPSVVAAASYASKIIKRTGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(47213..48178)
                     /locus_tag="VWX64_000562"
     CDS             complement(47213..48178)
                     /locus_tag="VWX64_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9190092.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(48159..49613)
                     /locus_tag="VWX64_000563"
     CDS             complement(48159..49613)
                     /locus_tag="VWX64_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9190093.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDKNWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGIYYELDYGRKTN"
     gene            49991..51874
                     /locus_tag="VWX64_000564"
     CDS             49991..51874
                     /locus_tag="VWX64_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9190094.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            52023..52910
                     /locus_tag="VWX64_000565"
     CDS             52023..52910
                     /locus_tag="VWX64_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9190095.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(53230..53847)
                     /locus_tag="VWX64_000566"
     CDS             complement(53230..53847)
                     /locus_tag="VWX64_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU9190096.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(54262..>54475)
                     /locus_tag="VWX64_000567"
     CDS             complement(54262..>54475)
                     /locus_tag="VWX64_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190097.1"
                     /translation="IMHTTIGSNKNHNRFIRKWLPKPKGTKKTTTKEVAFIEKRINNY
                     PKKCLNYKSPREDFWMTNLNLKFSNN"
BASE COUNT        16300 a        10271 c        12304 g        15600 t
ORIGIN      
        1 tgtattcacg ccctcaatag acggtaaaat aagaaaattg tttatatatt gtctccgtag
       61 tgttattata cgaaataaaa gattttagga aaagtcgtta tatcatgcta tacctattct
      121 ttgtggtata attgcaagag gtttaatccg ataatttata aagagagaaa gatattcatg
      181 agagatttat tatctaaaaa aagtcatagg caattagaat tattagaatt attatttgaa
      241 cataaacgtt ggtttcatcg ttctgaacta gcagagttat taaattgtac agaacgtgca
      301 gtcaaagatg atctatccca tgttaaatct gcttttcctg acttgatttt tcattcttct
      361 actaatggta tacgcattat taataccgat gatagtgata ttgaaatggt ttaccatcat
      421 ttctttaaac attcaactca tttttcgatt ttagaattca tcttctttaa tgaaggttgt
      481 caagctgaga gtatttgtaa agaattttat atcagttcat cttcgctcta tcgtattatt
      541 agccaaatca ataaagtgat taaaaggcaa tttcaatttg aagttagtct gacccctgtt
      601 caaatcattg gaaatgagag agacattcgt tacttttttg cacaatattt ttcagaaaaa
      661 tattatttcc tagaatggcc atttgaaaat ttttcatcag agccactatc tcaattgtta
      721 gaattggttt ataaggaaac aagctttcca atgaatttgt caacgcatag aatgctaaag
      781 ttgctcctag ttacgaacct atatagaata aagtttggtc attttatgga agtagataaa
      841 gattctttta acgaccaaag tttggatttt ttaatgcagg cagaaggaat agaaggtgtt
      901 gctcagagtt ttgaatcaga atacaatatc tctttagatg aagaagttgt ttgccaatta
      961 tttgtgtctt actttcaaaa aatgtttttc atagatgaaa gtctctttat gaaatgcgta
     1021 aaaaaggata gttatgttga aaaatcttac catctattga gtgattttat tgatcagatt
     1081 tcagtcaagt atcagattga aatggagaat aaggataatc tgatttggca tctgcataat
     1141 accgcacatc tgtatcgtca agagttgttt actgagttta ttttatttga tcaaaaaggg
     1201 aatacaatca ggaactttca aaatattttt ccaaaatttg tttcagatat aaaaaaagag
     1261 ctttctcact atttagagac tcttgaggtt tgttctagtt caatgatggt aaatcatcta
     1321 tcttatacct tcatcactca taccaaacat ttggtgatta atttgctaca aaatcagcct
     1381 aaactaaagg ttttagttat gagtaatttt gatcagtatc atgcaaaatt cgttgcagag
     1441 acactttctt attattgtag caataatttt gaactggaag tttggactga attagaatta
     1501 tcaaaggaat ctttagaaga ttcaccttat gatatcatta tttctaattt tattattcct
     1561 cctattgaaa ataagagact catctattca aataatataa acacggtctc actcatatac
     1621 ttgttaaatg ccatgatgtt tattcgatta gatgagtaac caaaaataac aaaaaaacgc
     1681 tatttcgcgt ttgaactgta cctcaaaagt tagacagaaa aagtctaatt ttgggggtgt
     1741 ttttgttaag aaaagacctt caatcattta agcaaaatgt acatctagat ttatagccat
     1801 ctaaaactct tgcttttttt atagaagata cgaaaaaagc catgaaacca aggcttttcc
     1861 tgttttatgt agatgtttac acatgaaaat tgaagtattt tcaaaagcta attggagtga
     1921 ttttattcat gatgggataa atgatctggc caaaaatgat tgagaaatag ttgcttaaaa
     1981 agcatttgca tgatactata tattgaaagg aggtgataat atggtagaac aaagaaaatc
     2041 aattaccatg aaagatgttg ctttagaagc aggagttagt gttggaactg tttcacgtgt
     2101 aattaataaa gaaaaaggca ttaaagaagt aactttgaaa aaagtggaac aagcgattaa
     2161 aactttgaat tacattccag attactacgc tagaggaatg aaaaaaaatc gaacagaaac
     2221 gattgcaatc attgtaccaa gtatctggca tcccttcttt tcagaatttg ctatgcatgt
     2281 ggaaaatgaa gtctataaga gaaataacaa attactctta tgttctatca atggtacaaa
     2341 tagagagcaa gactatctgg agatgttgcg tcataataaa gttgatggag tggttgccat
     2401 tacctatagt ccaattgaac attacttgac gtcaggaatt ccctttgtta gtattgaccg
     2461 cacatactca gatattgcca ttccttgtgt ttcatcagat aatgatgcag gtggaagaga
     2521 agcagctaaa caattaatta gtaaaggatg tcagcattta gcctttgtgg gcggacataa
     2581 tacaaccatt aatgaaacca aacgtcgtag aatttcattt gaaaagtatg tccaagagca
     2641 taaaatacct cttagtattt ttgatttgga tgagacagtt actgactatt atggaaagct
     2701 agagagtttc ttggaagaaa attcttctat agatggaatt tttacaatca acgattttac
     2761 agctttggat gtgattgaaa tactagaaaa aaatggcaaa cgtattcctc atgatgtcca
     2821 aattattgga tacgatggaa ttaaaatggc tggagataga gattatctac tttcaactat
     2881 tgaacaacca ttggaagaaa tggcaaaaga agcggttcgt attttgtttg atataattga
     2941 tggaaagact gttaatttgc agacaatcct accagtaaaa tttgttgaag gaaaaacaac
     3001 aaaaaatgaa aataagtctt gacagaaagc gctatcaatg atagaatgaa ttcagataaa
     3061 aagatttatt tttaaaacaa aaatgaaacg tttcaaaaaa gaaataaaga gacagcgcca
     3121 agcgctatct tttctagaaa aaaatgaaac gtttcaaaaa aggaggttgc tatgaatagc
     3181 aaagcgaagc aagtttctct ttgggaaaga atcaagaaac aaaaactctt gttattgatg
     3241 actgtccccg gtttagtttt aacctttatc tttaaataca tccctatgta tggggtttta
     3301 atcgcattta aagattacaa tcctttaaaa ggaattttag ggagtgattg gattggtttt
     3361 tctgagttta caaaattcat atcctctccc aactttggta tcttgttagc caacacatta
     3421 aaattaagta tctatggttt attgcttggc tttttaccac caatcattct cgcgattatg
     3481 ctcaatcaac tcttgagtga aaaagtcaaa aaacgaattc agctcatttt atacgcacca
     3541 aactttatct cagtcgttgt tattgtcggt atgattttcc tcttcttttc agtgggagga
     3601 ccaatcaaca attttctttc tatgtttgga atgaaggctg acttcttgac aaatccagac
     3661 ttctttagac ctttatacat ctttagtggt atctggcaag gaatgggctg ggcttcaacg
     3721 ctctacacgg caacattggt aaatgtagat ccagccttag tagaagcagc ccgactggat
     3781 ggagccaata tcttccaacg aatctggcac attgatattc cagctcttaa gcctattatg
     3841 gttatccaat ttgttttagc tgcaggtgga attatgaatg tcggatatga aaaagcattc
     3901 ttgatgcaga catcgttaaa tttgccaact tctgaaatta tctcgacata tgtctataaa
     3961 gttggtcttg tatcaggaga ctattcttac tcaacagcgg ttggtttgtt taatgcagtg
     4021 attaacgtag tattgcttgt tgcagttaac caaatcgtta aacgcatgaa taatggtgaa
     4081 ggaatttaag gaggaaagta tgaaaaattc gattatggat acaaaatttg atagacgtat
     4141 cttactctta aataaaatca ttattgtctt tatcgttttg atgactttgc ttcctttact
     4201 ttatatcgtc gtagcatcct ttatggatcc taaggttctg gttagtagag ggattagctt
     4261 taatccagcc gattggactg tagaaggtta ccagcgtgta ttcagtgacc aatctattct
     4321 aagaggtttt atcaattctc tactatactc ttttggattt gcagctttaa cagtcttgct
     4381 atctgtgttt acagcttatc ctctttctaa gaaagacttg gttggacgtc gttggattaa
     4441 ctacttcttg attgtaacta tgttctttgg tggtggttta gtcccaactt acttgctcgt
     4501 aaaagaattg ggaatgctca atattccatg ggctatcatt gttccaggtg ctgttaacgt
     4561 ttggaatatt attcttgcta gggcctattt ccaaggattg cctgaagaat tagttgaaac
     4621 tgctgtcatt gatggtgcaa atgatttaca gattttcttc aaaatcatgc ttcctcttgc
     4681 aaaaccaatt atgtttgttc tcttccttta tgcttttgta ggacagtgga actcatactt
     4741 tgatgcaatg atttatatca aggatccaaa cttggaacca ttgcaacttg tacttcgtaa
     4801 aattctcatt cagagccaac caggtcaaga catgattgga gcacaagcgg ctatgaatga
     4861 aatgaaacgt ttagctgaat tgattaaata cgcaactatt gtcatttcca gcttgccatt
     4921 gattgttatg tatccattct tccaaaaata ctttgataaa ggaattatgg ctggttcact
     4981 taaaggataa aaaaagaaaa aataaaagga gttttctcat gaaattcaaa acattctcaa
     5041 aatcagcagt tttgttgaca gctagtttag cagtacttgc agcctgtggc tcaaaaaata
     5101 cagcttcaag tccagattat aagttggaag gtgtaacatt cccgcttcaa gaaaagaaaa
     5161 cattgaagtt tatgacagcc agttcaccgt tatctcctaa agacccaaat gaaaagttaa
     5221 ttttgcaacg tttggagaag gaaactggcg ttcatattga ctggaccaac taccaatccg
     5281 actttgcaga aaaacgtaac ttggatattt ctagtggtga tttaccagat gctatccaca
     5341 acgacggagc ttcagatgtg gacttgatga actgggctaa aaaaggtgtt attattccag
     5401 ttgaagattt gattgataaa tacatgccaa atcttaagaa aattttggat gagaaaccag
     5461 agtacaaggc cttgatgaca gcacctgatg ggcacattta ctcatttcca tggattgaag
     5521 agcttggaga tggtaaagag tctattcaca gtgtcaacga tatggcttgg attaacaaag
     5581 attggcttaa gaaacttggt cttgaaatgc caaaaactac tgatgatttg attaaagtcc
     5641 tagaagcttt caaaaacggg gatccaaatg gaaatggaga ggctgatgaa attccatttt
     5701 catttattag tggtaacgga aacgaagatt ttaaattcct atttgctgca tttggtatag
     5761 gggataacga tgatcattta gtagtaggaa atgatggcaa agttgacttc acagcagata
     5821 acgataacta taaagaaggt gtcaaattta tccgtcaatt gcaagaaaaa ggcctgattg
     5881 ataaagaagc tttcgaacat gattggaata gttacattgc taaaggtcat gatcagaaat
     5941 ttggtgttta ctttacatgg gataagaata atgttactgg aagtaacgaa agttatgatg
     6001 ttttaccagt acttgctgga ccaagtggtc aaaaacacgt agctcgtaca aacggtatgg
     6061 gatttgcacg tgacaagatg gttattacca gtgtaaacaa aaacctagaa ttgacagcta
     6121 aatggattga tgcacaatac gctccactcc aatctgtgca aaataactgg ggaacttacg
     6181 gagatgacaa acaacaaaac atctttgaat tggatcaagc gtcaaatagt ctaaaacact
     6241 taccactaaa cggaactgca ccagcagaac ttcgtcaaaa gactgaagta ggaggaccac
     6301 tagctatcct agattcatac tatggtaaag taacaaccat gcctgatgat gccaaatggc
     6361 gtttggatct tatcaaagaa tattatgttc cttacatgag caatgtcaat aactatccaa
     6421 gagtctttat gacacaggaa gatttggaca agattgccca tatcgaagca gatatgaatg
     6481 actatatcta ccgtaaacgt gctgaatgga ttgtaaatgg caatattgat actgagtggg
     6541 atgattacaa gaaagaactt gaaaaatacg gactttctga ttacctcgct attaaacaaa
     6601 aatactacga ccaataccaa gcaaacaaaa actagaggtt gattatggga gataagaaat
     6661 acacagtaga aaaagccaat cgttttatag cagaaaataa acatctcgtt aatactcaat
     6721 ataagcctga agaacatttt tcagctgaga ttggttggat caatgatcca aatggatttg
     6781 tctattttcg tggagaatac catctctttt atcaattcta tccatatgat agtgtttggg
     6841 ggcctatgca ctggggacat gctaaaagta aggacttggt gacttgggag cacttgccag
     6901 tggcacttgc tcctgaccaa gattatgacc gaaatggttg tttctcaggc tctgccattg
     6961 tcaaggatga tcgcctctgg ctcatgtaca ctggacatat cgaagaagaa accggtgtcc
     7021 gccaagtgca aaatatggta ttttcagatg acgggattca ctttgaaaag atttcccaaa
     7081 atccagttgc aactggatca gacttaccag atgagttgat tgctgctgat ttccgtgatc
     7141 caaaactctt tgaaaaagat ggacgctatt actccgtagt agctgccaaa cacaaggata
     7201 atgtgggctg tatcgttcta ctagggtccg ataacctagt agaatggcag ttcgaatcca
     7261 tctttttaaa agggggagaa caccaaggtt ttatgtggga atgcccagat tacttcgagt
     7321 tagatgggaa agattgcctt attatgtcac ccatgcgtta tcagcgtgag ggagactcat
     7381 atcataacat caactcatcg cttttgttca cgggtaaggt agattggaga gaaaaacgtt
     7441 ttatcccaga atcagttcaa gaaattgatc atggccaaga cttctatgcg cctcaaacat
     7501 tgttggacga tcaaaatcgt cgtatcctga ttgcttggat gcagacatgg gggcgtaccc
     7561 ttccaaccca tgaccaagaa cacaagtggg catgtgccat gactctacct agaattctaa
     7621 gattggaaga tggcaaacta agacaattcc ctgttaaaaa aggccaatat caaatccaaa
     7681 tagataaaga ttgtcattac cacttaggaa atgatataga ttatcttgaa tttggttatg
     7741 acagtaatgc gcagcaagtt tacattgatc gtagccatct tattcaaaaa attctaggtg
     7801 aagaagaaca ggacactagt cgacggtatg tagatattga agctaaagaa ttggaagttg
     7861 ttctagataa aaattccatc gagatttttg tcaatcaagg tgaagcaagc ttgactgcaa
     7921 cttattactt aacggtgcca gctgagctat cacgaattga ttaaaaatta agttatttct
     7981 cctaaagaaa aagttctctt tctaaaatag tggaaagagg actttttgtg ttttgggtat
     8041 ataagcttag tttatggtat ttgtaaaatt ggtgttggat tatgatttaa gctagttttc
     8101 taaagaattt gaaaaaaatt ttatttaagc aaaaaaacct tggttccaag gcttttcctg
     8161 ttgtatttag atgcccccta cagggatcga acctgtgacc cacggattaa gagtccgctg
     8221 ctctgccagc tgagctaagg aggcaaagaa aaaagctgta ttggtgccga aacttcacgg
     8281 tttgtattga acccgcgcaa ttaagcaggt gggcaactcg ctctaactga agctgtttcc
     8341 gtgtgagacg gcctacatgc tgttagaaga cttttgtttc cctaataata caaaaaatag
     8401 tcggtcaaca cttaagtgtg aagtcgtaca ccacagcgtt tctatactta tatgatacca
     8461 ctttttcaaa aaaaatcaag aggaaagtgc aattttttga aaaggatttc agatttttcg
     8521 caaacggtcg atagcttcct ttctttgagc caaagcccgt tcatatttac cagtatcttc
     8581 tgcttggaaa tagtgatgat tacgaatttt ttctggcaga tagtcttgct tgacccaatt
     8641 tccaggatag ttgtgtggat agagatagtc ttgggcattc cccagttcct tgcttccact
     8701 gtagtgccca tcacgtaggt gtcgcggaat aggcaagtgc cctgatgttt tgaggtcagc
     8761 aagtgcctta tccatagcta cataggctga gttggatttt ggagaaaggg ccaaatcaat
     8821 cacgacattg gcaatgagaa tgcgggcttc tgggaaccca atcttctggg cagcatccag
     8881 agcagtcacg gtatgaatct gggcctcagg attggctaaa ccgatatctt cataggcgat
     8941 aacagtcaag cgacgagcga gactaggcag atccccagcc tcaatcaagc gggcagcata
     9001 gtggagactg gcatccacat ctgagccacg gatagacttt tgcagggcag atagaacatc
     9061 atagtgaccg tctccatcct tgtccatagt gatgtagctt ctctgaagac tattttccat
     9121 gatgtctaag gtgatgtggc gaatgccctc gtcattctca ggggtagaga gaacagccaa
     9181 gtccagtgag ttaaaggcag agcgaaggtc tccgtttgta gaggttgcga tgaaatccag
     9241 cgcatcctca tctagttcta ttggaaaatt aaaaccacgt tcagggttac ttagagctat
     9301 ctgcagggcc tctttgacgt cttggttaga cagaggttcc aactcaaaaa tttgaacacg
     9361 gctacgaatg gcaggagtga cggaaaagaa aggattttca gtcgttgctc caatcatgat
     9421 gaccagtcca ctttccaaga gaggcaagag gaagtcttgc ttggtcttat ctagtcgatg
     9481 aatttcgtct agcaatagga cgagaccgcc agaaaattta gcctcttcgg cgatttcttg
     9541 gagtcttttt ttactatcaa ctgtcgcatt gaaagttcga aaggcatact tggtcgttcc
     9601 agcgatggca gaggcaatac tggttttgcc gattccagga gggccatata gaatcatgga
     9661 ggacaggcgg ttggcttcca ccatgcggcg gatgattttt ccaggtccga ccagatgctc
     9721 ctgaccgatg acctggtcga tggttttagg gcgcatgcga agcgcgagat tgtctggcat
     9781 agcagtcctt tctaacgtgg atttgagtag aatgactcat ctactatatc ttactatgtc
     9841 cattctagcc tattagttgt gatatttcaa tggttttgta ataatcaggg agtgagatag
     9901 aatctttttt actatttaat ttaatgagga gaggtatcag catgagagat ttgattttcc
     9961 ttaaagctca aaataggata gttgagccta aagaagtgga agtgctgact tgagaaataa
    10021 tattgctaaa tgtcattgta tgaactataa tgaaaagaga ggtgataagc aatggaaatg
    10081 atggaccaag tcaggaaatt ttgattttta caaaacaaat tcgtcattgg attcttagtg
    10141 atcaagttat ttcagggaaa agaaaacttt tcttccggga agatactcca aaagagattt
    10201 tagatttgta cgaaaacatt aaatctaaac ttgattttgc ttaccaagaa gttcattcta
    10261 ataatgggtt gaaaaaatat gaaaaataga ataattgatg tttttgaagt agtaaatcgc
    10321 ctccttgtaa taactgttga aaatcctgat ttcgaagact tgagagttaa tcatactcaa
    10381 tgaaaatcaa agagcaaact aggaaactag ccgcaggctg tacttgagta cggtaaggcg
    10441 acgttgacgt ggtttgaatt tgattttcga agagtatcag tttgtaaaaa ttggagataa
    10501 aaaatataga gtacgcagtg gtcctatgat tcattcaact ccgcctcaat ctgtcttaga
    10561 tcgagatact tttacaattg actatacaga tgatgaattg ctcgataaag aagcagtttt
    10621 tactactcat tagaaaaata ggtatgaata aattggcttc ccttagaacc acatctaggg
    10681 gcttttatgt ataatagaat aataagtatc actcctttac aatacgtgta acacgtgtta
    10741 taatggtgtt gtcaggaggt aaaagcgcta tgcctatgac acaaaaagag atggttaaac
    10801 tccttacggc ccatggttgg ataaagacta gaggcggtaa aggctcccat attaaaatgg
    10861 aaaagcaagg ggaaagacct atcacaatcc ttcatggtga gctgaataag tacactgaaa
    10921 gagggataag aaagcaagct gggttgtaaa attcagcccc tgctttttga tatggaggta
    10981 gtgaaatgtt agttacgtat ccagctttat tttattatga cgacacagac ggaacagaag
    11041 cgacttattt tgtccatttc ccagattttg aatactcagc tacacaagga gaggggattt
    11101 ctgaggcttt ggctatgggg tcggagtggc tagggataac tgttgcagat ttgatagaga
    11161 gtgatggaga gttacctcag ccatcagata tcaatagctt gtctttaatt gataatgatc
    11221 cttttaaaga tgatgaagat ttcgtgtcaa cctatgacct tgataaatct tttatttcta
    11281 tggtatctgt tgatgtatca gaatacctag gaagtcagga acccattaaa aagactttga
    11341 ccataccaaa atgggcagat aagttgggac gagaaatggg acttaacttt tctcagactt
    11401 tgacagacgc tattgcagat aagaaagttc aagcctaaga ttaagcgtgg tatcgtggta
    11461 atagtcaata aaaaagcacg tccacttgtg ctagttactc gcctattgat tttatagatt
    11521 tattagccct ttcgcgggct ttttatattg atttttatga gaaatgaaga aatcagactt
    11581 ttaagaaaat cactgatacc aagggtttaa atgaggtaat atggtataat taggacataa
    11641 aataattttg tggtaagatg gtagtatcta ttttagcata tttccgagca atcggggcga
    11701 ttaaagagtc gcatagaaag aggacaaaat ggcaacatac ggatttttag atgttttaga
    11761 ggaagagttg gacaagaact ttccctttga ctttgagatt agctgggaca aacgcaacca
    11821 tgcggtagaa gtgagttttc tattggaagc gcaaaatgct gcaggtgtgg agatggtgga
    11881 tgaagacgga gaggtttcat cagatgacat tctttttgag gaagcggtcc ttttctacaa
    11941 tcctgccaag tcaacagtca atgaggaaga ctatttgact gttattcctt acctgcctaa
    12001 aaaaggattt tcccgtgaat ttttagctta tttttcgctt ttccttaaag atactgctga
    12061 ggttgggcta gatgtcctca tggacttttt ggaagaccca gaagcagagg aatttatcat
    12121 ggaatggaac caagaagtct ttgaagaagg aaaagttggc ttggaagagg gagaatttta
    12181 tccttatccg agatactagg agttggttgg aggtgttatg aagaaaattg ggacttattt
    12241 ggtttatgtg ctagctgttg tctttattat gctagctttt gcttgtggaa caatcgcatt
    12301 tgcagagttg gggtattccg cagttttagc ctttactttt ggttatgcct tcgctcttct
    12361 aagcatgtat ttaattttta ttcttcatga gctgggtcat gctttttgtg gctacttgac
    12421 aggctatcgg ctggtggctt ttggattagg acattttatt ttgaccaaaa agtcaggcag
    12481 gtttcatctt agtagaacag ccattctgaa aaatgttggt gctcaataca ttggtttaaa
    12541 agaggatgaa agcgatcaaa gaatcatcct gatgctttca ggaggcttga tggttcatct
    12601 cggcttgata ttattggcga tagtgtttgg atttttgaca agaagctggt attttgcagg
    12661 gacttggatt tttcttaatt tatctttctt cctaaataac attttgccag tcgacatcac
    12721 cgatggagca aaaatttggg aattactaca acaccctgaa aataccaaat acgcctacct
    12781 ggtattgaga cattctgctc aaactttgct ggctcctcaa gaatatgatt tgaaagactt
    12841 tgttcaagca gttcctgagg atgcacgagg gagttttgcg gatggtgtat taggtatgca
    12901 aggtgaagtt tccattttgg aagggaagga agaagtagct aaacagcagt ttcaagcatt
    12961 acttgagagg gcaactactc cgatgatgca gacagttgcc caactatccc tgcttcatat
    13021 cgccttgttg gaaggagatt ttgagcaagc ggagcaatat gctagtattc gacaggtcaa
    13081 atcgtttctg tctctcaaac tgtccaatct tcaagtgata caagcctggt atcaattaaa
    13141 ggtgaagaaa gatgtagatc gaactcgtaa ggctctcaag attgctagac agaaaatgga
    13201 tagtagtcga atgttgaggg acgagaaacg ctattatgaa aacttgttag ccgagctgga
    13261 aaaggaaatg ttagaaggaa ctgaagatgg aactagaaat ttctggtttc ccaggctgta
    13321 agattgcttt gttttgtggg gataagctct tgactatctt acgtgatgat aaggcaagta
    13381 ttccctgggc caatatgtgg gaactgccag gtggtggacg tgaaggtgat gaaagtcctt
    13441 ttgagtgtgt agcgcgtgaa gtttatgaag aactgggcat tcatctgact gaagattgtc
    13501 tgctttggag taaggtttac ccaagtatgc tttttgcaga caaacagtcc gtttttctag
    13561 ttggtcagtt gacacagaac cagtttgaca gtatcgtatt tggagatgaa ggacagggct
    13621 atcagctgat gaatgttgag gaatttctta gttccagtca agttgtgcct cagttgcaag
    13681 agagattaaa agattattta aaagtaagtg attagaaagg atggttcagt taaatttcta
    13741 aactgaaccc gccctaaaca ctgtgccaaa aagataaact tctcttagac acaagcgtct
    13801 tcagagaatt tcctattttg gttttgtgtt ttacgggctt ggtatcttaa taatggaaac
    13861 atggcaagag ttaaaagtta cagtgaagcg tgagggagag gagttggttt ccaatctctt
    13921 gattgagctg ggagcgcaag gagtcgcgat tgaagacagc atggactata tgggaaatgt
    13981 ggatcgtttt ggcgagattt tcccagaggt ggagcagcaa gaagaaatcg tagtgacagc
    14041 ctactaccct gacacggtgg atgtgacagt ggttgaggcg gacttgcagg ctcgcttagc
    14101 agaattgacg gattttatgg atttgggtga agtcaagatg gggacgactg ccttggctga
    14161 ggaagactgg gcagacaact ggaagaaata ctatgagcca gctcgtatca ctcatgattt
    14221 gaccatcgtt ccctcttgga cagactatga ggcgactgcg ggagaaaaaa ttatcaagct
    14281 agatcctggg atggcttttg gtactgggac ccatccaact accaagatga gcctctttgc
    14341 cttggaacag gttcttcgtg gtggcgagac agtgctagat gtggggactg gttcaggggt
    14401 tctctccatt gctagctcgc tacttggtgc caaggaaatc ttcgcctatg acctggatga
    14461 tgtggcggtt cgtgttgctc aggaaaatat tgaacttaac cctggaatgg aaaatatcca
    14521 cgttgctgct ggagacttgc ttaagggtgt tgagattgag gcagatgtga ttgtagctaa
    14581 tatcttggcg gatattctca ttcatctgac agacgatgcc tatcgtttgg tcaaggatga
    14641 aggctacctg atcatgagtg gcattatcaa ggacaagtgg gacatggtgc gcgagtcggc
    14701 tgagtcagct ggatttttcc ttgaaaccca catggttcaa ggggaatgga atacctgtgt
    14761 ctttaagaaa accaaggata tctctggtgt gattggaggc tagcatgcag cagtattttg
    14821 taaaaggcag tgctatctct cctgtcacta tcgaggacaa ggaaaccagt aagcatatgt
    14881 ttcaggttat gcgcttgaaa gaagaggatg aggttacctt agtctttgat gatggcatca
    14941 agcgcttggc gcgcgtgctg gatatggaaa atcgtcagtt tgagttggtc caagaattaa
    15001 atgacaatgt ggaactacca gtccaagtga ccatcgcatc tggatttccc aagggagaca
    15061 agctggagtt catcgctcaa aaagtaaccg aactgggtgc tagccaaatc tgggcctttc
    15121 ctgcagactg gtcagttgcc aagtgggatg gcaagaaatt gggtaaaaaa gttgaaaaac
    15181 tagaaaaaat tgcccttgga gcagccgagc aaagcaagcg taatattgta ccaagtatta
    15241 aacttttcga gaaaaaagca gattttctag ctcagctgga ccagtttgac tttatcatag
    15301 tagcctatga agaatcagct aaagaaggag aagccgctgc gcttctgcaa gcagtcactg
    15361 gtcttgaaac aggagccaaa ctgctcttta tctttggtcc agaaggcggt ctctcacctg
    15421 cagaaatcga aagttttgaa gctaagggag ccgttttggt aggcctaggt cctcgtattt
    15481 tgcgagcaga aacagcaccg ctttacgcct tatcagccct tagtgtttta gtagaattag
    15541 agaaataaga ggaagaaaat ggaacaaaaa caccgttcag aatttccaga gaaggaactc
    15601 tgggacttaa cagccctata ccaagaccgt gaggatttct tgcgtgcaat cgagaaagct
    15661 cgtgaagaca tcaaccagtt tagccgtgat tacaagggca atcttcacac ttttgaggat
    15721 ttcgagaagg cctttgcgga attagaacag atctacattc agatgagcca tattggcaac
    15781 tatgctttta tgcctcagac gacggactat agcaatgacg aatttgccaa tattgcccaa
    15841 gctgggatgg aatttgaaac agatgccagc gtagccttga ccttctttga cgatgccttg
    15901 gtggtagcag acgaggaagt cttggaccgt ttgggtgaat tgcctcactt gacggcagct
    15961 attcgtcagg ccaaaatcaa aaaagcccac tatctagggg ctgatgtgga gaaggccttg
    16021 accaatctcg gtgaagtttt ctatagtccg caggacattt atactaagat gcgagctggg
    16081 gattttgaaa tggctgactt tgaagcccat ggcaagacct ataaaaacag ctttgtcacc
    16141 tatgagaatt tctaccaaaa tcacgaggat gctgaggttc gtgagaaatc cttccgttcc
    16201 ttctcagagg gacttcgtaa gcaccaaaat acggctgcag cagcctatct ggctcaggtc
    16261 aagtctgaaa aactcttggc tgatatgaag ggatacgact ctgtatttga ttatcttcta
    16321 gctgaacaag aagtggaccg tgtcatgttt gaccgccaga ttgacctcat catgaaggac
    16381 tttgcaccag tcgctcagag atacctcaag catgttgcca aggtaaatgg tcttgaaaag
    16441 atgacctttg cagactggaa attggacttg gacagcgccc tgaatcctga agtgactatt
    16501 gacgatgcct atgatttggt catgaagtcg gtagaacctt tggggcaaga atattgtcag
    16561 gaagttgctc gttaccaaga agagcgctgg gtggactttg ctgctaacag tggcaaggat
    16621 tccggtggtt atgcggcgga cccatatcgc gtacaccctt atgtactcat gagctggaca
    16681 ggccgtttga gcgatgtcta taccttgatt catgaaatcg ggcattctgg tcaattcatc
    16741 ttttcagaca atcaccaaag ctatttcaac gcccacatgt cgacctatta tgttgaagca
    16801 ccgtcaacct tcaatgaatt gctactcagt gattacttag agaaccagtc taataaccca
    16861 cgtcaaaaac gcttcgctct ggctcatcgc ttgacagaca cctacttcca taatttcatc
    16921 acccacctct tggaagccgc cttccagcgt aaggtgtata cattgattga agaaggggag
    16981 acctttggag caagcaagct caacagcatt atgaaggaag ttttgacaga tttttggggc
    17041 gatgccattg aaatcgacga cgatgcagct ttgacttgga tgcgccaagc tcactactat
    17101 atgggcttgt atagttacac ttactctgct ggtcttgtca tctcgacagc tggttacctt
    17161 catcttaaaa actcagaaac tggagctgaa gactggctca atctcctcaa atcaggtggt
    17221 agcaagacac cacttgagtc agccatgatt atcggtgctg atatttcaac agacaaacca
    17281 ctccgtgata ccatccaatt cttgtctgac acagttgacc agattatcgc ctacagtgct
    17341 gagttggggg agtaagggga atagaaaaat tttctagaat gatgtttatg ggcttgttaa
    17401 gcgtcattct atttgtctta gttgtagcta ttttcaaaaa tgtcgttgaa ggtcgtgatg
    17461 ttaaatttga acttactgta gaactggtat tgatagttat ttacgtcatt ttatatcaga
    17521 ttgtatttaa ttgagaattc aatattgagt catttaagac tgcctttttg aacagttgct
    17581 agaaatgtag aggtattgac catgtatcaa gatttactaa gaaaaatagc agaagaaaaa
    17641 ccaaattata accaggaaga aatccagtgg ttgtttgatc atttgggaaa tccttctcca
    17701 gaaattcgtg atgacctttc aaatcaaggc ttgcactatc tttcaaaaga aaaggataca
    17761 acagatttct caagtcagta tggttgggtt catgcttttg cacatggagc cgatttactg
    17821 acagaggtgg tttgtcatcc agactttcct ataaacagaa ttcatgaagt atttgacata
    17881 cttggccaac tatttaaaag aatgtcgatt cgctttacag atgatgagga ttggcgttta
    17941 gcaagagtga tctatgaacc tattttacaa gggaagttgg agcaagaaca agtagcttct
    18001 tggataaaaa ctgttgattt tccgatagaa gaaagggagg atttttacaa attttccaac
    18061 tttagatcct gtctggtgga agtctatgtc caacttgacc agagaaatag tttacaagat
    18121 gacctgaaag aagctatcca gtcttttcaa tactagagat tagctaatag ttctatgatt
    18181 ttcaaaaaat ttccaatcaa ttttcttgaa accctttcct acttttgata gactagtatc
    18241 tagtttttga aaaaaggaga aagaaaatga aaaaatttgt tgctgagtta atcggtacgt
    18301 tcatgcttgt gttcgttggg acaggagctg ttgtttttgg aaatggtctt gatggccttg
    18361 gtcaccttgg aatcgccttt gcctttggtt tggcaatcgt ggtggcagcc tactcaatcg
    18421 gaactgtttc aggtgctcac ttgaacccgg ctgtttcgat tgctatgttt gtaaacaaac
    18481 gtttgtcatc ttcagaactt gtaaactaca tccttggtca ggttgttgga gctttcatcg
    18541 cttctggcgc agtcttcttc ctcttgggta attcaggtat gtcaactgct agtcttggtg
    18601 aaaatgcctt ggcaaacggt gtcactgtct ttggtggttt cttgtttgaa gtcatcgcaa
    18661 ctttcttgtt tgtcttggtt atcatgactg tgacttcaga aagcaagggc aatggcgcga
    18721 ttgctggttt ggtaatcggt ttgtcattga tggcgatgat tcttgtcgga ttgaagatta
    18781 ctggactttc agtaaaccca gctcgtagct tggcaccagc tgtcttggta ggcggcgcag
    18841 cccttcaaca agtttggatt ttcatccttg caccaatcgc tggtggagtt cttgcagccc
    18901 ttgttgcaaa aaatttcctt ggaacagaag aataattgaa actcaaaaag ccttgctcct
    18961 catcttgagg aacagggctt tttcgtatga tactcttcga aaatctcttc aaaccacgtc
    19021 agcttcacct tgccgtaggt atggttactg acttcgtcag ttctatccac aacctcaaaa
    19081 cagtgtttta agctgacttc gtcagtctta tctataacct caaacactgc tttgagcaac
    19141 ctgcggctaa cttcctagtt tgctctttga ttttcattga gtatgacttt agcggttgtc
    19201 aattttctct ggataaaggt cgtgttggag gaggcgttgt tctgccaagc cctcatactt
    19261 agttccttgc ttaccgtagt tatagtaggg gtcgattgaa atgccaccgc gcggagtgaa
    19321 ttttccccag acttctaaat agcgagggtc tagcaagttg accaagtctt tcccgatggt
    19381 gttgatacag ttttcgtgga aatctccgtg gtttcggtag ctaaatagat atagtttgag
    19441 ggattttgac tcgacacaga gcttgtcagg aatgtaggaa atatgaatcg tcgcaaagtc
    19501 tggctgagca gtgatttgtc ccagcagaga catatcgagg atatggtgac gaatgccctg
    19561 ttccttagcg atttctctag taatttgaat ttcgaggtga tgacgttggc cgtaggcaaa
    19621 ggtgacagct tcgactgttt catagtgttg catggcccag aaaaggcagg ttgttgaatc
    19681 ttgaccacca ctaaagacga ccaaggctga ttgacgtttc atagtactcc ttccaaaatg
    19741 ggaaatgttc agagcacgca aaaagctccc attagggagc taaaaaatac caaatcgagg
    19801 tttttttagc gatggcatat cccaaacatc gtaatattct acttatatag taaaatgaaa
    19861 taagaacagg acaaatcgat caggacagtc aaatcgattt ctaacaatgt tttagaagta
    19921 gaggtgtact attctagttt caatctacta tagtctagca tattttttga aaaatggcaa
    19981 agggcaagaa aaaagagacc aaagaaagta cttggtctct cgtttgatta gctcaattca
    20041 gcaatgatgg ccttgatttg ttctgctgtg tgaacacctg caacttgttt gacaacttgg
    20101 ccgtcttttt tgaagagaag agttggaata gacatgattc caaaagcacg agctgtgttt
    20161 ggattttcat caacgtccat tttaacgatt ttcaagacat cttctgaaag ttcttcagac
    20221 aatttgtcca agattggacc ttgcatacga catggaccac accaagttgc ccagaagtct
    20281 actaagacca aaccatcttt tgtttcttgt tcgaatgttg catctgtaat tgcttttgcc
    20341 attgtatttc tccttttttt agttatattg gcttaaatct tgtttcatga gatagaagaa
    20401 gatatctcca taagtcccat ggtagtccaa attatgaccc ttgtaagtta atttttggac
    20461 agggtagtag tctgcgacgc cgataaggca agcttgttgc gaacgttcaa agtcttcata
    20521 agactcgaaa gtcacagttc tttcgttctt gctggcatct atataggtaa tttcaatcat
    20581 gtttaaaact cctttgttta atgctaactt tattttactc cttataaaag agaatgtcaa
    20641 gaaaaatgat tgcgcacgca acttttttta aaatcatctt aaatcaagaa atccaaacct
    20701 gcttccaagc tttcttcgac agtcttttgt agcgaggcca gtgtcttttg cccatcattc
    20761 gtcaggcaga taaaactaga gcgtctatct tgatggcaac acatgcgact gagtagaccg
    20821 caatttttag cttccaagcg agccaccatc ctagaaactg cgcttggact cagatgaagc
    20881 ttatctggca ggtcaatctg gcgtagagat ttttcttcag ccaagtccag atagtagagc
    20941 aggtagaact ctttcaaggt cagactttgc tcgctctgtt gggcaatggt ctcttccaag
    21001 agactttcaa tttctttctg acgccgattg aagtcaaacc atttttccaa ataggtcata
    21061 gtgtctcctt tctttttaga gtcataaaat agaagaaagt ccattaacgg gcagtctctg
    21121 cgtcacaaga tgattgcgca tgcaataatt atactacttt tcaagaatgc tggcaagctc
    21181 tgttttttag tggttttatt ttttactgtc tatatttttg gtaaaaatca acttttactt
    21241 ggatgaaggt tttggcttca cgtaggagtt gaagaagggt ggcgcgggtt tcaaattctt
    21301 ctcttgtctt gggcagactg cggttccgga agacttccag ataacgttca atttcatcta
    21361 gcaaatcaga agcaggattg gtctggctca gttgacctgc aatttttgaa aagagttgcg
    21421 ctaagatcag gctttcactg gcggcaaggt gacaagtgtt aatctgttgg gccatgtttc
    21481 tcaggatacg actttgtcgc tgtctcatct caaagtagtg gatatggtag tcggtctggt
    21541 gaaagaggtg gtcagagtga tccaaataga ccagtctgag ggcttctttc aaaagcgtgt
    21601 ctaattctgc taccagctgt gctcggttgc gtccgtctcc tctggataaa tagtatttga
    21661 agcgctggag gatatctttt aacttttctt ccaccagcgt gtggtagtgc tggattttct
    21721 cttctcgtga aggcatgtag agattgacca gtaaagcaaa tcctgtaccg atagcaaaga
    21781 gaaggaattc attgactaga aggtctggag aggttgactc ttgaaccaag agatggctaa
    21841 ccaaaacagt gcttggtgtg atgccaattt cccagcccat cttgtaggct aaaggaacgt
    21901 agaaggccag atagaggccg agactccaga tatgaaatcc gctcaagtga aaagctagaa
    21961 caccgatagc cagagctaga agcatagaaa aaagacgatt gcgagccagt tttaaagtac
    22021 ttctacgcgt atcagatagg ctcaagagag cgataattcc agccgaaact gctgacgaaa
    22081 gattgagaaa ataagcaagc aggcaggcaa gacaggtagc taagatgagc ttggtcgtac
    22141 gttggctaat agacataaga atttcctaat aagttagaat aaaagcgtaa aagacaagac
    22201 atgagcaggc ttgccttgat gagttatttt ttacgggttg ctacgtattc ggcaacggcg
    22261 gtaaagaggc catctgtaga agagttaagg gctgtttcac atgagtcttg gatgacacca
    22321 atcacaaaac caaccccaac aatttgtatg gcaatatcgt tagaaatacc gaaaaggcta
    22381 caagcaactg ggataagaag gagggaacct ccggcaatac ctgaagcacc acaggctgag
    22441 atagctgcta ccacactgag gacaaaggct gtggcaaagt caacaggaat tccaagagtg
    22501 ttaactgcag caagggtcaa aaggttaatg gtaatcgcta ctccagccat attgatagta
    22561 gaaccgagtg ggatagaaac agaataggta tctgggttga gtccaaggtc atggcagagt
    22621 ttcatgttga caggaatgtt agtcgcagaa ctacgagtga aaaaggctgt cacactgctg
    22681 acacggaggc agttccaaac tagagggtaa ggattgcgtc tcataaagaa gaaggcaatc
    22741 aaagggttga ccacaggggc aacaaaaagc atagtcgtta ctaatggaac caataaaata
    22801 ccgtagttgg caaggcttcc gactcccttg tcagaaatgg ttttaaaaac aagaccaagg
    22861 attccaaatg gagccagatt gatgatccat tcgacaattt tagaagtcac gtcagcgata
    22921 gtttttagca attctttact atttttactg gcttctctca tagcgattcc aaaaatgact
    22981 gcccaagata agattccaat atagttagca gtaagcaggg cgttgactgg gctgtcaacc
    23041 agtttgagca agaggttgct gaggacctgc ccaatcccat ctggtggtgc aatttcagta
    23101 ttggcactat ttagggtaat ttcaataggg acgatgaaac ttgctagtac agctacaaga
    23161 gcagcggcga aagtccctat cataggatat acaagaaaac aacagttttc atattgctat
    23221 cttgtccctt ttgatgttgg gaaagggcat tggcaacgag ggcaaagact aggataggag
    23281 caacagcttt tagacctcca acgaataaat ctccgagtag cccaatccct gagagattag
    23341 gaagggtcag tcctaggatt ccccataaag cataccaatc aagatacgct tgacaaggct
    23401 tgccttattc caagcatgaa tgattctttt cataataatc ttctttttgt gtagtgatta
    23461 tgattatagt ataaatgata gacaaaatca agaattttct gtctattttt tgaatattta
    23521 tggagaatga gactgatgaa aatatggtat aatgaaataa aggagtttta tatgcaaaaa
    23581 tttattcagg cttatattga aaagctagat gtgacaacca ttatcgagaa tattctaacc
    23641 aaggtcattt ctcttttact gcttttgatt gtattttata ttgctaaaaa aatgcttcat
    23701 accatggtgc agagaattgt caaaccttct ctaaaaatgt ctcgtcatga tgtcggacgc
    23761 caaaaaacca tctcacgttt actagaaaat gtgtttaatt atacgctata tttcttttta
    23821 ctctactgca ttttgtcgat tttaggtttg ccagtttcta gtttgctggc tggagctggt
    23881 attgctgggg tagcgattgg tatgggagcc caaggctttc tatctgatgt catcaatggc
    23941 tttttcatcc tctttgaacg tcaactggat gtgggagatg aggtcgttct gacaaatgga
    24001 ccgattactg tatcgggtaa ggttgtcagt gtgggaattc gtacgacaca gcttcgtagc
    24061 gaggagcaag cccttcactt tgtccctaac cgaaatatca cagttgttag caatttctca
    24121 cgcacagact agacctgtta ttttaagtaa tttgtggtac aatagaggga gtttaataag
    24181 gagaaaagat ggttttagaa aagcagttgg gcaatggttg tacctggata gacctagacc
    24241 taggaaagtt gaataaacta gaagaccttt ctgaaattta cggtttggac aaggaaacca
    24301 ttgaatacgc actggataga aacgagcgcg cccacatgga ctaccaccgt gaaagtggga
    24361 cggttacctt tatctataat gtcctagacg taaaaaagga caaggcctac tatgagactt
    24421 ttcccatgac ctttatcgtc gagcatcgtc gcctgattac cattagtaat accaagaacg
    24481 cctatgtcat tgaacagatg actcgttatc tggagagcca tgacacgctt tcgatttata
    24541 agtttctctt tgccagtctg gaaatcatca gcaatgccta ctatcctgtc attgagcaga
    24601 tggacaagag tagggatgag gtcaatgacc tcttgcgcca gcgaactacc aagaaaaacc
    24661 tctttgccct gtctgatttg gagactggta tggtttatct gacggcagct gccaaacaaa
    24721 atcggatttt gttagagcat attcaaggtc atgccttgta tcgtagtttt gatgagattg
    24781 agagagaaca gtttgatgat gccatgattg aggctcatca gctggtatcc atgacagacc
    24841 taatctctca gattttacag cagctttcag cctcttacaa caatattcta aacaataatc
    24901 tgaatgacaa tttgacaacc ttgactatca tttcagtctt gctagctgtt ttggcagtcg
    24961 tgacaggctt tttcggaatg aatgttccct tacctttaac agatgagccc catgcttggc
    25021 tctatatcag tttggctagt gcaggtttgt ggattgtttt atccttgtta ctaaggaaaa
    25081 ttgcgaaaaa aagttaagaa aaggagccag aatggcgatt gaaaattata taccagattt
    25141 tgctgtggaa gcagtctatg atctgacagt cccaagcctg caggcgcagg gaatcaaggc
    25201 tgttttggtc gatttggata ataccctcat tgcttggaac aaccctgatg ggacgccaga
    25261 gatgaagcaa tggctacatg accttcggga cgcgggtatt ggcattatcg tagtgtcaaa
    25321 taacaccaaa aaacgcgttc aacgagcagt tgagaaattt gggattgatt acgtttactg
    25381 ggccttgaag cccttcacat ttggtattga ccgtgccatg aaggaattcc actatgacaa
    25441 aaaggaagtg gtcatggttg gcgaccagct catgacagat atacgagcag cccaccgtgc
    25501 agggattcgg tcaattttag tcaaaccctt ggtccaacat gactcaatca aaacgcagat
    25561 taaccgaact cgtgagcgtc gtgttatgag aaaaatcact gaaaagtacg gaccgattac
    25621 atataaaaaa ggaatttaac tatggaagaa attctctgta ttggttgtgg agcaaccatt
    25681 cagacgacag ataaggctgg tcttggtttt accccccagt cggcacttga aaaaggtttg
    25741 gagactggcg aagtctattg tcaacgctgt ttccgtctcc gccactacaa tgaaatcaca
    25801 gatgtccagt tgacgaacga tgatttcctc aagttcttgc acgaggtggg agacagtgat
    25861 gccttagtgg tcaatgtcat tgatatcttt gattttaatg gatctgtcat cccaggttta
    25921 ccacgtttcg tctcgggcaa tgatgtcctc ttggtaggaa ataaaaaaga tatccttcct
    25981 aagtcagtta agtctggtaa gattagccag tggctcatga aacgtgccca tgaagaaggt
    26041 cttcgtccag tcgatgtggt cctaacttca gcacaaaata aacatgccat taaggaagtc
    26101 attgacaaga ttgaacacta ccgtaagggc cgcgatgtct atgtggtcgg tgtgaccaac
    26161 gttggaaaat caactctaat caatgctatt atccaagaaa tcacgggtga tcagaatgtc
    26221 atcactactt cacgcttccc agggacaacc ttggacaaaa tagagattcc gcttgacgac
    26281 ggatcttata tttacgatac gccgggaatt atccaccgcc accagatggc tcactacttg
    26341 acggccaaaa acctcaagta tgtcagtcct aaaaaggaaa tcaagcctaa gacctatcag
    26401 cttaatcctg agcaaaccct atttttaggt ggtttgggac gctttgactt tatagcagga
    26461 gaaaagcaag gatttactgc tttctttgat aatgaactca aactccatcg tagcaagctt
    26521 gaaggagcta gtgctttcta cgataagcac ctgggaactc ttctgacacc accaaatagc
    26581 aaggaaaaag aagatttccc aaggctagtc cagcatgtct ttaccattaa agataagaca
    26641 gacctagtca tctcaggcct aggctggatt cgtgtaacag gcacagcaaa agtcgccgtc
    26701 tgggcaccag agggcgtcgc cgtcgtcaca cgaaaagcaa ttatttaaaa caaaatcgct
    26761 gagcgaacaa agtgagctca tatagcgata gttattgccg tggtgtgatt gccaatctgt
    26821 agattggcaa ggggcacaat tgagaccaag gctcaattgt gaggtcagga aatccatttt
    26881 tcaaagatga aatctttgga aaattagttc cgaccgtccc tcaccaccta aaataactat
    26941 ccaaaaacaa ggaagaaaat tatgtcatta acatcaaaac aacgtgcctt cctcaacagc
    27001 caggcacaca ccctcaaacc tatcatccaa atcgggaaaa atggactcaa cgaccaaatc
    27061 aaaaccagcg tccgtcaagc tcttgatgcg cgtgaattaa tcaaggttac tctcttacaa
    27121 aacacagatg aaaacatcca cgaagtagct gaaattttgg aagaagaaat cggtgtggat
    27181 acagtccaaa aaataggacg catcttgatt ttgtttaaac aatctagcaa gaaagaaaat
    27241 cgcaagattt ctaagaaagt caaagaaatc taagatcgaa actccaaata actgttttta
    27301 tagagaaata aaggggacta gcctatgaca atcgaactat tgactccctt taccaaggta
    27361 gagttggagc cagaaatcaa ggagaaaaaa cgcaaacaag ttgggatttt aggggggaat
    27421 tttaaccctg ttcacaatgc ccatctcatt gttgcggatc aagtacggca acagttggga
    27481 ctggatcaag ttctgctcat gcctgaatac caacctcctc acgttgataa aaaggaaacc
    27541 atccctgaac accatcgtct caagatgctt gagttggcaa ttgaggggat tgacggccta
    27601 gtcattgaaa ctattgagtt ggagcgcaag ggtatttcct acacctacga caccatgaag
    27661 attttgacag agaagaatcc agatacggat tactacttta tcatcggtgc cgacatggtt
    27721 gactatctgc ctaagtggta ccgaattgat gaactggttg acatggttca gtttgtgggg
    27781 gttcagcgtc cacgctacaa ggtagggcct tcctatccag ttatctgggt ggacgtaccg
    27841 ctcatggata tctcgtccag catggtgcgg gacttcattg cccaaggtcg gaaacccaac
    27901 tttctcttac ctcagccagt gctagactac atcgagaagg aggggctcta ctgatgtcct
    27961 atcaagacta tatcaactgc tcccgtgagg ccttgttgga aaaaatggca gagcttctac
    28021 ctgagaaacg tctaacccat tgtctaggtg tggagcgtgc cgctatggaa ttagctcagc
    28081 gctttggtgt agatgttgag aaagcaagtc tagcaggtct tcttcatgac tatgctaaaa
    28141 agttgtcaga tcaggaattt ctagacttga ttgaccgtta tcagctagat ttcgacctca
    28201 aaaactgggg taataatgtc tggcatggta tggtcggaat ttacaaaatt caggaagatt
    28261 tggatttgca tgattcagaa atcctgcgag ccattgaagt ccatacagtc ggtgctggtc
    28321 agatgacaga cctagataag gtcatctacg tcgcagacta tatcgagcac aatcgagcct
    28381 ttcctggagt agatgtggcg cgtgagattg caagtctatc gctcaataag gcggtggcct
    28441 acgaaacagc tcgtaccgtg gagtatctag ctcatcaggg attccccatc tatccccaaa
    28501 cccttgaaac ctataacgcc tttgtgcact atttgaaaga gaactaaatg aagacggctt
    28561 ttataatcat tgatgttcag aatgttttag tagaaactgg gttccagaca aaaagtctat
    28621 tgggaaaaat ttcttattta caaaaccagg ctagaagcaa gaatattgaa attatctatg
    28681 ttcaacatat tgagaactct gaagctcaaa catcagaaga ttggcagtta tctgcgcttt
    28741 taaatcgaaa acctgctgaa aaggtctttc agaagaagta taacagtatt ttcaaagaaa
    28801 ctggcttaaa agaatacttg gataaacagg ggattgaaaa attagtttta tgtggtatgc
    28861 agacagaata ttgtgtggat acctctgtca aggttgcctt tgaatatggc tatcagctta
    28921 ttgttccaga aggtgctgtc acaacctttg atggggatga cattccagca gaaacgatta
    28981 atgaatttta tgaggacatt tgggaggagc actttgcaga tgtcctagat tacaaacata
    29041 ttttctaaaa agaggattaa atgaacgaaa aagaattact agaactagtc gtgaaagcgg
    29101 ctgatgagaa acgtgcggag gatatcctcg cacttgatgt acaagatttg actagtgtga
    29161 cggactactt tgtcatcact agctcaatga atagccgtca gttggacgct atcgcagcta
    29221 atatccgtga aaaagtagct caagcgggct ttaaaggtag ccatgtcgaa ggcgatgcag
    29281 ctggaggctg ggtcttactg gacctcggtg ctgttgtcgt gcatatcttt tcagaagaaa
    29341 tgcgtgccca ttataaccta gagaagctat ggcatgaggc gaattcagta gatatttcag
    29401 aagctcttgc ttagaagatg aactcagttg tagtcaactg ggtttctttg cttattttag
    29461 aaaaattgat agaaaggtaa agggctagtg gtgtttacca tggagctctt agtatcatga
    29521 ttatggcgac ttatgaaacc ttcgcggcgg tctatgatgc ggtcatggac gatagtttat
    29581 acgacaaatg gacgaatttt tctctgcgtc atttgcctaa gaccaaggag agaaagaaac
    29641 tcttggaatt ggcttgtggg acaggaattc aatcagtgcg cttctctcag gctggttttg
    29701 atgtgactgg acttgacttg agtgcggata tgttgaagat tgcggagaag agagcaactt
    29761 cagccaagca aaagattgct tttatagaag gtaatatgct aaatttgtcc aaggcaggga
    29821 aatacgattt tgtcacgtgt tattcggact ctatctgcta tatgcaggat gaggtggaag
    29881 taggggacgt ctttaaggac gtgtacaatg cgctgaatga agagggagtt ttcatctttg
    29941 acgtgcactc gacctaccag acagatgaag tattccctgg ctattcctac catgaaaatg
    30001 cggaagattt tgccatgctt tgggatacat atgaggacga agctcctcac tccatcgtgc
    30061 atgagctgac tttctttatc aaggaggctg acggttcctt tagtcgccac gatgaaatac
    30121 atgaggagag gacctatgag ctcttgacct atgatatctt gctggaacag gctggattta
    30181 agtccttcaa actctatgca gactttgagg ataaggagcc aacagaaact agcacccgtt
    30241 ggttttttgt ggcgcagaag taggagatta gcatgaccat cacaggtatt atcgcggagt
    30301 tcaatccttt tcataatggc cataaatacc tgctggatca ggcagaggga ctgaaaattg
    30361 ttgccatgtc agggaatttc atgcagcgtg gagagcctgc tattgtggat aagtggacaa
    30421 gggcccagat ggcgctggaa aatggcgcag acttggtagt ggaattgccc tttttagtca
    30481 gtgttcaggc agctgatttc tttggtcaag gagctgtgaa tatcttggat cgcttgggca
    30541 ttgatagtct agtttttggg acagaggaag ttcgagatta tcagaaaatc gctgacttat
    30601 acacagagaa aggtgctgag atggagaaat ttgtggaaaa tctgactgat tccctttcct
    30661 atccccagaa aacccaagct atgtggaagg aatttgctgg tcttgatttt tcaggtaata
    30721 cccccaatca tgttcttgct ctggcctatg ccaaggcggt tgcaggacgg aatatcaagc
    30781 tgcatccgat tcagcgtcag ggggcaggtt accattctgt gaataaagat gtggactttg
    30841 cctcggcgac agccctccgt caacatcaga aggaccaaga tttcttagaa cgttttatgc
    30901 cttctgttgc cctatttgag caggccagta aggtgatctg ggaagactat tttcccttgc
    30961 tccgctatca aatcttgtca aatcccgacc taaccaccat ctatcaggtc aatcaagaaa
    31021 tggctgtgcg cattaaagaa gctattaaaa cagcccagtc tgtggaagaa ttggtcgagt
    31081 tagtgactac caaacgttac accaaggcgc gtgtcagacg cctattgacc tatattttga
    31141 tgcaggctag agaaagtgac ttgccagaag ccattcatgt ccttggattt actgaaaaag
    31201 gcaggcaaca tctcaagtct ctgaaaggac aggtcaatct agtcagccga attggcaaag
    31261 aaccttggga tgctatgact caaaaggttg accagattta ccaactagga aagccaagta
    31321 tagcagagca aaattttgga agagtgccga ttagaataga aacaaactaa gtctaccgaa
    31381 aggtaggctt tttgagattt tttacgaata atactctgcg aaaatcaaat tcaaatcgcg
    31441 tcaacgtcgc cttgccgtac tcaagtacag cctgcggcta gtttcctagt ttgctctttg
    31501 attttcattg agtataaata gatagaaaag aaaatcttgt acaagttcct gacaatttct
    31561 ttcttttcgt gtataatagt ggaaaagagc taaaacgagg tgtggttatg gaagcagtcc
    31621 tttactcaac attccgaaat catttaaagg actacatgaa gaaggtaaat gataaatttg
    31681 agcctttgac ggtggtcaat aaaaatccag atgaggacat tgtagttctt tcaaagagcg
    31741 aatgggacag tattcaggaa accctgagaa tcgcccaaaa taaggagtta tcagacaagg
    31801 ttttgcgagg aatggataaa attcgtgcag gacactagtc taatttacag agaatacctg
    31861 agtgaaatct tgctgttgtt agaaacaaat ttcttgcatt ctaacgatta ttaggaagtc
    31921 tactgaaaag taggcttttt ctcaaatctt tactaaacca cgatttctaa gaaatagaga
    31981 ttgtgccaat aaattatagg catttaaact ccaatttccc caaaacatat tctattttag
    32041 gtttgtgaaa atcacttttt tatggtagaa tgtaaaagaa tgtatgtcat tcggaataac
    32101 aataaaatga ggtaaaaaca tggaaatcat gtcgcttgcg attgctgttt ttgccgtcat
    32161 cattggttta gtcattggat atgtcagcat ctcagctaag atgaaatcat ctcaggaagc
    32221 tgcagagttg atgcttttaa atgctgaaca agaagcaact aatttacgtg gacaagctga
    32281 gcgtgaagcg gatttacttg ttaatgaagc caaacgtgaa agcaagtctc ttaaaaaaga
    32341 agcactattg gaggccaaag aagaagccag aaaataccgt gaagaagtgg acgctgaatt
    32401 caaatcagaa cgtcaagaac tcaaacaaat cgaaagtcgt ttgacagaga gagctactag
    32461 ccttgaccgt aaggacgaca atttgacgag taaagaacaa acacttgaac aaaaagaaca
    32521 aagtatttct gatagagcga aaaaccttga tgcgcgtgaa gagcaattag aggaagtcga
    32581 aagacaaaaa gaagcagaac tagagcgtat tggtgctctg tctcaggcag aagcacgaga
    32641 tattatcttg gctcagacag aggaaaactt gaccagggag attgccagtc gcattcgcga
    32701 agctgagcaa gaggtcaagg aacgttctga caaaatggcc aaggacatct tggttcaagc
    32761 tatgcaacgt atcgctggtg aatatgtagc ggagtcaaca aactcaacag ttcatctgcc
    32821 agacgatact atgaagggac gcattattgg tcgtgaaggt cgtaacattc gtacctttga
    32881 aagtttgaca ggggtcgatg tgattatcga cgatacacca gaagtggtga ccttgtcagg
    32941 atttgatccg attcgtcgtg agattgcccg tatgactatg gaaatgttgc tcaaagatgg
    33001 tcgtatacat ccagctcgta tcgaagagtt ggttgagaaa aaccgtcaag agattgacaa
    33061 taagattcgt gaatacggtg aggctgctgc ctatgaaatt ggtgcgccaa accttcatcc
    33121 agacttgatg aagattatgg gacgtttgca gttccgtact tcatatggac aaaatgtttt
    33181 gcgccattcg attgaggttg ctaagttggc tggtatcatg gcgagcgaac ttggtgaaaa
    33241 tgcggctctt gcccgtcgtg ctggattcct tcacgatatc gggaaagcca ttgaccatga
    33301 ggttgaaggt agccacgttg aaatcggtat ggaattggcc cgtaagtaca aggaaccccc
    33361 agttgtggtg aatacgattg ctagtcacca cggagatgtt gaagctgaga gcgtgatagc
    33421 agttatcgtc gctgcagcag atgccttgag cgcagcccgt ccaggtgctc gtagtgagtc
    33481 tcttgaaagc tacatcaagc gtctccatga tttggaagaa attgctaacg gctttgaagg
    33541 agtgcaaact agctttgccc ttcaagcagg acgtgaaatt cgtatcatgg tcaatccagg
    33601 aaaaatcaag gacgacaaag tcacaatctt ggctcacaaa gttcgtaaga aaattgaaaa
    33661 caatctcgat tatccaggaa atatcaaggt aaccgtgatt cgcgagcttc gtgcagtaga
    33721 ttatgctaaa taaataagaa agagcagttg aaaaattact gcttttttgt tacactagat
    33781 agaaagactg taaaggataa tctggctttt tgccattatt ctagagaaat gttatttcac
    33841 agattgacta aaaggagaca caatggcaga ccgaggctta ctaatcgttt tttctggtcc
    33901 ttcaggggtt ggaaaaggaa cggttagaag agagattttt gagagttctg aaaaccaatt
    33961 tcaatattct gtatcgatga cgacacgcgc acaacgtcct ggagaagtgg acggtgttga
    34021 ctatttcttc cgtactcgtg aagaatttga agagctgatt cgtcaaggac agatgttgga
    34081 atacgcagaa tatgtcggca actactatgg aactcctctg acctatgtca atgaaacctt
    34141 ggacaaggga atcgatgttt tccttgaaat tgaagttcag ggtgctcttc aggtcaagaa
    34201 aaaggttcca gatgctgtct ttatcttcct gacaccacca gatttggatg aattgcaaga
    34261 acgcttggta ggtcgtggaa cagatagtgc agaagtgatt gcccaacgaa tcgaaaaggc
    34321 caaggaagaa attgccctca tgcgtgagta tgattatgcg attgtcaacg atcaggtacc
    34381 cctagctgct gaacgtgtca aatgtgtgat tgaagcagaa cacttctgtg tggatcgtgt
    34441 cattggtcac tatcaggaga tgttaccaaa atctccaact acccgataaa atttagaaaa
    34501 taggtacaag caaatgatgt taaaaccctc tattgatacc ttgctcgaca aggttccttc
    34561 aaaatattca ctcgtaatct tggaagcaaa acgtgcccac gaattggaag caggtgcccc
    34621 agcaactcaa ggtttcaagt ctgaaaaatc aactcttcgc gctttagaag aaatcgaatc
    34681 aggaaacgtt acaattcacc cagatccaga aggaaaacgt gaagcagtgc gtcgccgtat
    34741 cgaagaagaa aaacgccgca aagaagaaga agaaaagaaa atcaaagagc aaattgctaa
    34801 agaaaaagaa gatggtgaaa aaatttaagg ttggggggac tcaatcttat tttttctatt
    34861 gcaagaatgt actgacaagg aggaggtgag aagatggccc tagctaagat tatcgtagat
    34921 gtgcccttga tgcagacgga ccagccctat agttacagga ttccggagga atttgaggga
    34981 atgctggaag ttgggatgcg ggttcatgtg ccttttggta agggtaatcg cctgattcaa
    35041 gggattgttc ttggtttgga gtcccaatca gatggagaag agatggagca agatttaaaa
    35101 gatattgcag aggtgctgga tttttctcct gttctcacgc cagaacaact ctggctggct
    35161 gaggagttac gcaaatctgt cttctcctac aaaatctcta tcctcaaggc catgcttcca
    35221 gggtttctga attctagcta tgacaagatt ctctatccta tggaaggctt gagtcaggaa
    35281 gaacgagtgc gcctgtttgg ttcagaagat tcgctagcct tttcttcact agaccttgcc
    35341 aagcaagctg aaatgatgcg tttgactaga aaaggcctgc ttggtctgga atatcaggca
    35401 gtcgatcaaa agaaggtcaa gacccagtct tggtatgagg ttgaccatgc tcaattagaa
    35461 ggtattgaga tttctacacg tgccaagaaa aagttggaac tgagagatta tctgctgtct
    35521 catccagaga gcgcttcctt ggctagcttg ttagagtcct actcgcgaga gcaagtcaac
    35581 ttctttgtgg atcaaggtgc tgttaccata gtccaaaagg aagttcgacg ctcggctgct
    35641 tattttgaag gaattgaagc aagtagacct ttggagttaa atccagaaca aagacaggcg
    35701 cgtgatgcgg ttgtgagttc tattggcagt tctcaacctc cctttctact tcaagggatt
    35761 acaggaagtg ggaagaccga ggtttacttg cagattatcc aaggtgccct ggataagggc
    35821 aagacagcta ttttgctggt acctgagatt tccttgactc ctcagatgac cgagcgtttt
    35881 atagcacgtt ttggggacaa ggtagccatt cttcactcag gattatccaa tggtgaaaag
    35941 tatgatgaat ggcgcaaggt ggagcgtggc gatgcccaag ttgttgttgg tgccagatct
    36001 gctatctttg ctcctctgaa aaatctgggt gtcatgatta ttgatgaaga gcatgaagcg
    36061 gcttataagc aggacagcaa tccccgttac catgccagag aggtagctat tttacgggct
    36121 cggtataatc aagcaactct ggtacttgga tctgcaacgc cgagcttaga gagccgggca
    36181 cgtgctggca aaggcgtcta tcaacactta cgtctaaccc aacgtgccaa tcctttggct
    36241 acaatccctg aggttcaagt gattgacttt cgagactata tcggacaaaa tgagacgtca
    36301 aactttacgc ctcctttgct agaggctatc caagaccgtc tggttaaaaa agagcaggtg
    36361 gttctcatgc tcaatcgccg tggttattct agctttgtca tgtgtcggga gtgtgggacg
    36421 gtggatactt gtcccaactg cgatatttct ctgaccttgc atatggatac caagactatg
    36481 aactgccatt attgtggttt ctcgaaggat attcctcagg tctgtcctaa ctgtaagagc
    36541 cgcagtattc gttactatgg gacgggaact cagaaggctt atgatgagct agcagaactc
    36601 tttccccaag ctcgcattct gaggatggat gtggatacga ctcgaaagaa aggcagtcac
    36661 caagccttgc ttgaccagtt tgggcgaggg gaagcggata ttttacttgg tactcagatg
    36721 attgcaaagg gtttggattt tcccaatgtt accctagtcg gagttctaaa tgcggatacg
    36781 gccttgaatc tgcctgattt ccgttcttct gagagaacct tccagctctt gactcaggtg
    36841 gcaggtcgag caggtcgtgc tgaaaaggca ggtcaagtct tgatacagtc ctacaatccg
    36901 cagcactatg ctattcgatt tgccaaggat caagattacg aaggctttta tgcctatgaa
    36961 atgggaatca gacgacaact cggctatcca ccttactatt tcacgattgg tattaccctt
    37021 tctcacaaga aagaagaaga ggttttcaaa cgtgcctatg aagtcatgaa cattttgcgg
    37081 tcaggcttgt cagagaccag tcccattctg gggccaacgc caaaaccgat tgcccgtacc
    37141 cacaacctct atcattacca gattttaatt aaataccgtt tagaggatga gctggggccg
    37201 accctcaacc aggttttagc cttgactcaa gaacgggaaa atagtgagct ccgtctcagc
    37261 attgaccatg agccgcagca atttttataa gaaggagaag atatgacaaa actaatcttt
    37321 atggggaccc ccgacttttc agcaacagtc ttaaaaggac ttttgacaga tgaccgttac
    37381 gaaattctag ccgttgtgac ccagccagac cgtgctgttg gtcgtaaaaa agttatccaa
    37441 gaaaccccag tcaagcaggc tgccaaggaa gcaggactat ctatctacca acctgaaaaa
    37501 ttatctggaa gtccagagat ggaagatctt atgaagctag gagcagatgg aattgtgact
    37561 gctgcttttg ggcagtttct cccaagcaaa ctccttgata gcatggactt tgctgtcaac
    37621 gttcatgcct ccctccttcc tagacaccgt ggtggtgcgc ctatccatta tgccttgatt
    37681 caaggggatg aggaagctgg tgtgaccatc atggaaatgg ttaaggaaat ggatgcagga
    37741 gatatgattt ctcgtcgcag cattccgatc acagatgagg acaatgttgg caccttgttt
    37801 gaaaaattgg cgctagttgg tcgtgatttg cttttggaca ctctgcctgc ctatattgct
    37861 ggtgatatca aacctgaacc gcaggatacg agtcaggtta ccttctctcc aaatataaag
    37921 ccagaggaag aaaaactgga ctggaacaaa accaatcgtc aactctttaa ccaaattcgt
    37981 ggaatgaacc cctggcctgt tgcccatact ttccttaagg gcgaccgctt taagatttat
    38041 gaagccctac cagtagaagg tcagggaaat ccaggtgaaa ttctctctat cggcaagaaa
    38101 gaattgattg tcgcaacggc tgaaggggct ctatccctca aacaagtgca gccagctggt
    38161 aagcctaaga tggacattgc ttccttcctc aacggagttg gacgtacatt gactgtagga
    38221 gaacgatttg gtgactaaag tagaaacggc tagaagttta gctctagcag tgctagagga
    38281 tgtttttgtg aaccaagcat attcaaatat cgccttaaat aaacacctca aggggagtca
    38341 gctttctgca gcagacaagg gcttagtgac cgagctagtc tatggaacgg tagcccgtaa
    38401 actgactctg gaatggtacc tatcccactt tatcgaagac agagaccagt tagacagctg
    38461 gctctatgtc cttcttctca tgagtgccta ccaactccgc tatttggaca agattccaga
    38521 tcatgctgtg gtcaatgaag cagtggaatt ggccaaactc cgtaaaaaag gcagtgaaaa
    38581 attggtcaac gctgtccttc gccgtatctt gcgtgaagac tggccagata ttgctagcat
    38641 caagcgaaaa aacaagcgtg actccattgc ctattctctc ccagtttggc tagttgccaa
    38701 actcaaggaa gaatacggag aggagagagc aaaagccatc tttgaaagcc tgttagtgcg
    38761 aaacaaagcc agtattcgtg taacagacct aagtcgaaaa gaggaaatcc aagccttgtt
    38821 ggaggcgaat aattcccttt tagcaaccac tggtctggtt aaggagcagg ggcattttgc
    38881 agggcataat ttgtttgcgg atggagccat taccatccaa gacgagtcca gtcagctggt
    38941 tgctccgacg cttgatttac aaggtgatga gcgagtgctt gatgcctgtg cggctccagg
    39001 tgggaaaaca gcccatatag cctcttatct tacgacaggt caggttactg ctctggactt
    39061 gtacgaccac aagttggatt taattcaaga aaatgcccaa cgtctgggag ttgaagatcg
    39121 ggttcaaact caaaaattgg atgccagaaa ggtgcatgag ttttttgacc aggattcctt
    39181 tgataagatt ttggtggatg ctccttgttc aggaatcggt cttttgcgcc gaaaaccaga
    39241 tatcaaatac aataaagaaa cggcagattt cgcgtccttg caggaaattc agttagaaat
    39301 attaggtagt gtttgtcaaa tactaggcaa aggtggtata ataacttata gcacctgcac
    39361 tatcgtctca gaggagaatt ttcaagtcgt taaggccttt ttagagagtc atcccgagtt
    39421 cgagcaggta aaactagaac atgaatgtaa ggatatcatg aaagacggct gtatcctcat
    39481 tacacctgaa ttgtatggaa gtgatggatt cttcatcagt caatttcgca agatatcgga
    39541 ttaggaagga actgacacat ggaaatttca ttattaacag atgttggtca gaaacgaaca
    39601 aataaccaag actatgtcaa ccactatgtc aatagagctg gacgtaccat gattatttta
    39661 gctgatggga tgggaggtca tcgcgcaggg aatatcgcta gtgaaatggc ggtgacagac
    39721 ctgggtgtag cttgggttga tacccagatc gatacagtca atgaagtgcg tgaatggttc
    39781 gcccattacc tagaaattga aaatcaaaag attcaccagc ttggtcagga tgaagcttac
    39841 agaggcatgg gaactacttt ggaagtcctt gctattattg ataatcaggc tatctatgct
    39901 catattggtg attcgcgtat cggcttgatt cgtggagaag aataccatca gttgacgagc
    39961 gatcattctt tggttaatga attgctcaag gctggtcaat tgacaccaga agaggcagaa
    40021 gctcatccac aaaaaaatat tatcacccag tctattgggc aaaaagatga aattcagcct
    40081 gattttggga cagttatcct tgagtcaggt gactatctct tgctcaatag tgacggcttg
    40141 accaacatga tttcaggcag tgagattcgt gatattgtaa ccagtgatat tcctttagca
    40201 gataaaacgg agacacttgt tcgttttgct aacaatgcag gaggtttaga caacattacg
    40261 gttgcccttg tttctatgaa cgaggaggat gaagaatgat ccaaatcggc aagatttttg
    40321 ccggacgcta tcggattgtc aaacagattg gtcgaggagg catggcggat gtctacctag
    40381 ccaaagactt aatcttagat ggggaagaag tggcagtgaa ggttctgagg accaactacc
    40441 agacggaccc gatagctgta gctcgttttc agcgtgaagc gagagctatg gcagatctag
    40501 accatcctca tatcgttcgg ataacagata ttggtgagga agacggtcaa cagtatcttg
    40561 caatggagta tgttgctgga ctagacctca aacgctatat caaggaacat tatcctcttt
    40621 ctaatgaaga agccgtccgt atcatgggac aaattctctt ggctatgcgc ttggcccata
    40681 ctcgaggaat tgttcacagg gacttgaaac ctcaaaatat ccttttgaca ccagatggga
    40741 ctgccaaggt cacagacttt gggattgctg tagcctttgc agagacaagt ctgacccaga
    40801 ctaactcgat gttgggctca gttcattact tgtcaccaga gcaggcgcgt ggttctaagg
    40861 cgactgtgca gagtgatatc tatgccatgg ggattatttt ctatgagatg ttgacaggcc
    40921 atatccctta tgacggggat agcgcggtga ccattgccct ccagcatttc cagaaacccc
    40981 tgccgtccgt tattgcagaa aatccatctg tacctcaggc tttagaaaat gttattatca
    41041 aggcaactgc taaaaagttg accaatcgct accgctcggt ttcagagatg tatgtggact
    41101 tgtctagtag cttgtcctac aatcgtagaa atgaaagtaa gttaatcttt gatgaaacga
    41161 gcaaggcaga taccaagacc ttgccgaagg tttctcagag taccttgaca tctattccta
    41221 aggttcaagc gcagacagaa cacaaatcaa tcaaaaaccc aagccaggct gtgacagagg
    41281 aaacttacca accacaagca ccgaaaaaac atagatttaa gatgcgttac ctgattttgt
    41341 tggccagcct tgtattggtg gcagcttctc ttatttggat actatccaga actcctgcaa
    41401 ccattgccat tccagatgtg gcaggtcaga cagttgcaga ggccaaggca acgctcaaaa
    41461 aagccaattt tgagattggt gaggagaaga cagaggctag tgaaaaggtg gaagaagggc
    41521 ggattatccg tacagatcct ggcgctggaa ctggtcgaaa agaaggaacg aaaatcaatc
    41581 tggttgtctc atcaggcaaa caatccttcc aaattagtaa ttatgtcggc cggaaatctt
    41641 ctgatgttat cgcggaatta aaagagaaaa aagttccaga taatttgatt aaaattgagg
    41701 aagaagagtc caatgagagt gaggctggaa cggtcctgaa gcaaagtcta ccagaaggta
    41761 cgacctatga cttgagcaag gcaactcaaa ttgttttgac agtagctaaa aaagctacga
    41821 cgattcaatt agggaactat attggacgga actctacaga agtaatctca gaactcaagc
    41881 agaagaaggt tcctgagaat ttgattaaga tagaggaaga agagtccagc gaaagcgaac
    41941 caggaacgat tatgaaacaa agtccaggtg ccggaacgac ttatgatgtg agtaaaccta
    42001 ctcaaattgt cttgacagta gctaaaaaag ttacaagtgt tgccatgccg agttacattg
    42061 gttccagctt ggagtttact aagaacaatt tgattcaaat tgttgggatt aaggaagcta
    42121 atatagaagt tgtagaagtg acgacagcgc ctgcaggtag tgtagaaggc atggttgttg
    42181 aacaaagtcc tagagcaggt gaaaaggtag acctaaataa gactagagtc aagatttcaa
    42241 tctacaaacc taaaacaact tcagctactc cttaaaagca gatggataat caaaatgagt
    42301 aatcaatctt tgtcatgatt tcatggcaaa gatttttttt gagtccagat ttgtgataga
    42361 atagagggag ttgataaaag gaggaaagca tggaagaatc aaaagaatta aatgccgtca
    42421 ttgatgtgat tatgctagcg gggactattc tccttaaaag tggctcagaa atccatcgtg
    42481 tagaagatac catgattcga atcgcgcatt cgcaggggat tgtggattgc aatgtccttg
    42541 ccatgcctgc cgctatcttt ttctctattg aaaataccaa tatttcgcgc atgaagcgcg
    42601 tgacctcctc ttcttataac atcgaaaaag tctgcgatgt gaaccagatt tctcgtcagc
    42661 tagttggggg gcagattgac ttagaaacag cctttaagca attgacggcc ttgcaagctc
    42721 aaccccttcc ctatactaag ttgcaggtaa ctctggctgc gacctttagt gctcctttct
    42781 tttcagttat gtttagcgga aatatctacg acgcacttgg ggcaggagtg gcgaccttat
    42841 ttggttttgc cttttccctc tatgtggaaa aatttatccg aattcccttt gtgacagcct
    42901 ttgctggagc ttttgtcttt gggataattg cccagttttg ggctcgctac acaggttttc
    42961 cttcaacggc agatttgatt atagctggtg cggtcatgcc gtttgtacca ggtattgcct
    43021 tgaccaatgc ggtccgtgat attatgacca accacataaa ctctggtatg agtaagatgt
    43081 ttgaatccct gctcattacc ctcgctttag gggcaggaac ttctgtcgcc ttggtattga
    43141 tgaactaata tgacactaac aaccttttta ttacaagcag tagcaagttt tcttgccatt
    43201 atcacttttt taatcgtact taatgtgcaa cggtctatgc tcttacctgg agggattttg
    43261 ggcatgactg tctggctaat ctatctcttg ctcaaggaac cgaccaatgt cattgtagct
    43321 accttcattg cagccattat tggttcttgt gtcagccaga ttttaagtat tctttataag
    43381 acacctgctg tggtctttat cttggccatt ttggcaccgc tggttccagg ttatctctcc
    43441 taccgaacaa ctgccttttt tgtgacaggg gactataata aagcactggc aagtgcgacc
    43501 ttggttgtca tgttggcttt ggtaatctct attggaatgg ctagcggaac agtgattctc
    43561 agactgtatc attatataaa aacacatcga gtatcgtaga ctttacagaa ataaaagaat
    43621 tttctgaaaa atgagataaa taaattaaca acgctttcta tatgtgcgag aataccgcac
    43681 ttatgaagaa attgcggctg attttggtat ccacgaaagc aacttaatcc gtcggagcca
    43741 atgggttgaa gtaactcttg ttcaaagtgg tgttacgatt tcaagaactc ctctcagttc
    43801 tgaggacacg gtaatgattg atgcgacgaa agtaaaaatc aatcgcccta aaaaaagaat
    43861 tagcgaatga ttctggtaaa aagaaatttc acgctatgaa gactcaggcg attgtcacaa
    43921 gtcaagggag aattgtttct ttggatatca ctgtgaacta ttgtcatgat atgaagttgt
    43981 tcaaaatgag tcgcagaaat atcggacaag ctggtaaaat cttggctgac agtggttatc
    44041 aaggacccat gaagatatat cctcaagcac aaacttcacg taaatccagc aaactcaaac
    44101 cgctaacagt tgaagataaa gcctgtaacc atgcgctatc taaggagaga agcaaggttg
    44161 agaacatctt tgccaaagta aaaacgttta aaatgttttc aacaacctat cgaaatcatc
    44221 gtaaacgctt cggattacga atgaatttga ttgctggtat tatcaatcat gaactaggat
    44281 tctagttttg caggaagtct actactttac ttattgtctg taaatctact gaccttgttg
    44341 tttatcccag tcatggtttc tagttcgggc tcagagtttc aaagtggatg gtaagagcat
    44401 caattgattg ctgagaaggt tagtaaaaca cttgacaaga catttgataa ggatgtcaga
    44461 gaaattccga ccagtcagtt ttatcaaaaa tttgtagatg agatgggaag gacttactca
    44521 ggaaatttga tcctccagga gctgataact gtgaatggag cttataaagc tacttatatc
    44581 ggtgaactct ctagcaacta atcattcttt aaaatgatga ccaataagag gcttgatttg
    44641 gtgaatcaag tcttttttct ctcttttact gccatttgtg ataaaatagt atagaacgat
    44701 tttttacatg aatgataaaa cagaggtaaa tatgacaatc ggtattgata agattggttt
    44761 tgcgaccagt caatatgtct tgaaattaca agacttagca gaagcgaggg gaattgaccc
    44821 tgaaaaatta agtaaaggac tcttactcaa ggaattgagt attgcgcccc taactgagga
    44881 tatcgtgacc ttggcggcca gtgctagtga ctctatttta actgagcaag aaagacaaga
    44941 agttgacatg gtcattgtgg cgaccgagtc aggaattgac cagagtaagg ctgcggccgt
    45001 ctttgtgcat ggcttgctgg gcatccagcc ctttgctcgt agtttcgaga ttaaagaagc
    45061 ctgctatggg gcgacagctg ccctccatta tgccaaattg catgtggaaa attctccgga
    45121 gtccaaggta ttggtcattg ccagtgatat tgccaaatat ggtattgaaa ctccgggaga
    45181 accaactcaa ggtgctggaa gtgtagctat gttgattaca caaaatccac gcatgatggc
    45241 ctttaataat gacaatgtag ctcagacccg tgacatcatg gatttctggc gaccaaatta
    45301 ctcgacaact ccttatgtaa atggtgtcta ttctacccaa caatacttgg atagtttgaa
    45361 aacgacttgg cttgaatatc aaaaacgcta ccagcttact ttggatgatt ttgctgctgt
    45421 ttgtttccac ttgccttatc ctaaattagc gctaaaaggc ttgaaaaaaa tcatggataa
    45481 gagcctgcct caagagaaaa aagacctctt acaaaagcat tttgaccagt ctattctcta
    45541 cagtcaaaag gtggggaaca tctacacagg ttcacttttc cttggacttt tgtctctctt
    45601 ggaaaataca gatagcttga aagctgggga taaaatcgcc ctttatagtt acggaagtgg
    45661 agctgtggct gagttcttca gtggtgaatt ggttgaagga tatgaagctt atttggataa
    45721 agaccgtttg aacaagctca accaacgaac tgccctatcc gttgcagact atgaaaaggt
    45781 cttttttgag gaagtaaact tggatgaaac aaactctgcc cagtttgctg gctatgaaaa
    45841 tcaagatttt gccttggttg aaattctcga ccaccaacgc cgttatagca aggttgaaaa
    45901 ataatgaaga taagttggaa tggattttct aaaaaatcat accaagagcg cctcgagctg
    45961 ttaaaagctc aggcgctcct tagtcctgag agacaagcta gtctggagaa ggatgaacag
    46021 atgagtgtga ctgtggcaga ccagctgagt gagaatgtgg tgggaacttt ttctctgcct
    46081 tattcgctgg ttccggaggt acttgtcaac gatcaggaat acaccgttcc ctatgtgaca
    46141 gaagaaccct ctgtggttgc ggcggccagc tatgccagca aaatcatcaa gcgtacaggt
    46201 ggttttactg cacaagtcca tcagcgacag atgattgggc aggtagccct ttatcaagtt
    46261 gctaatccta aactagcgca agagaagatt gccagcaaga aagcggagct cttggagctt
    46321 gccaatcaag cctatccttc tatcgttaaa cgtggaggtg gggcgcgtga tctgcatgtc
    46381 gagcagataa aaggcgaacc agactttctc gttgtttata ttcatgtcga tacccaggaa
    46441 gccatgggtg ccaatatgct caacaccatg ctggaagcct tgaaaccagt cttagaagaa
    46501 ctcagtcagg gacagagtct catgggaatc ctgtccaact acgcgactga ttctctggtg
    46561 actgcaagct gtcgcatcgc ctttcgctac ttgagccgcc aaaaggatca aggacgagag
    46621 attgcggaga aaattgcgtt ggctagtcag tttgcgcagg ctgatcctta ccgagctgct
    46681 actcataata aaggaatttt taatggtatt gatgcgattt tgattgccac tggtaatgac
    46741 tggcgtgcca tcgaagctgg ggcccatgcc tttgccagtc gagatggacg ctatcaaggt
    46801 cttagctgct ggacgctgga ccttgaaaga gaagaattgg tcggtgagat gaccctgccc
    46861 atgcctgtag cgactaaggg tggctctatc ggcctcaacc cacgtgtagc tctcagtcat
    46921 gatctactag gaaatccttc tgccagagaa ttagcccaga ttatcgtgtc catcggtctt
    46981 gctcaaaatt ttgcagccct caaagccttg gtaagtacgg gcatccagca aggccacatg
    47041 aaactacagg ccaaatctct agctctccta gctggggcta gtgaatctga agttgctccc
    47101 ctagtagagc gcctcatctc agataaaacc tttaacctag agacagccca gcgctatctc
    47161 gaaaatttaa gatcataaaa actcagacga atcggtctga gttttcttgt gtttaaatac
    47221 tttttcctgg taatagcgta actggtaaga agtaaccagt tgtggcgact tccttgcctt
    47281 caatcttttg caagagaaga tcaatagtga gacaagcaat ctcttccaaa ggttgcttga
    47341 tagtagccaa ttgagggtag taattttcga taaagtaggt cccatcatag ccgatgacct
    47401 tgagctcttt tgggacagaa attcccaatt cttgagcgat tttaatgacc agaatagctg
    47461 tcaaatcatc cgaagcaaaa atggcatctg gtttttcccg ggtcaagata ttcttgattt
    47521 ccatttcttt tctgacggga gaaaagtcac tggaaacatt gataatagga gcttttggga
    47581 gtacggatgc aaaaccagcg tggcgcagtc cggttggcga attggaattg tcattccctg
    47641 taatcatgat gatagactgg gcacctgtct tgaccaaggt ttgggcagca agaaccccac
    47701 cagcatagtt gtcagaggag acaacaggga tgtctggcga taggtttcgg tcaaaggaaa
    47761 taatcggcgc tgtcacacga ttgtagtctt cgattcctag gttgtgacta ccagaaatga
    47821 tgccgtctac ctgattggct tccaacattt cgatgtattc gcgttccttc tcagaatcat
    47881 gttcactgtt gcagatgatg gtcttgtaac catttttgaa gagttggtgt tccaatttat
    47941 caatcaattc tgcatagaaa acattggaaa tattggggaa aatcaagccg attaacttag
    48001 ctgattttcc ttgcagacta cgagccaggt tgttgggttt atagcccaat tctctcatgg
    48061 cttcattgac tttttggatg gttttctcag atagataccc ttttttattg ataacccgag
    48121 aaacggtagt aggactgacg cctgcaagtt tggcgacatc agttagtttt gcgaccataa
    48181 tctaattcat agtaaattcc agttgggttt ccagatttga tcaggatacc attttggtcc
    48241 gcatgtggga agacacgacc agaaaatact ttttctcctt tattgatgaa aatttcaaag
    48301 acagagttat cgatgaagat tgtagcagta gtagcctgat tctcgatagg gcaagaacga
    48361 gttgtcccaa attcttgggc atactgttct ccagcctggc tacgatccac tgtcacttga
    48421 ccgtttacaa ggtcaaagtt gattgaaagt cccttacctt ctttatcagc aagtaagaca
    48481 atctcgctct ggctattagc ttccaagttg agttcaagtt cgtaagtgtt cttggtttgg
    48541 gaacggtttg agaaggcttc ttcagaagca cgaaggtcct taatagcagc gactggatac
    48601 tggtagagct tgtcgtcttt gatagtgagt tccttgacca aagagaaggt tccttggtgg
    48661 tcaaaacggt cagatgggta agaaacatct ggcaaaccaa gccagctaac tgctagagca
    48721 cgcccatcag gagcgttgaa ggcttgagtt gcataggctt cgaaaccgta atccatgttt
    48781 tgaagttgag acacatctac cattttggca tttttagggt caaaggaagc cccaatctta
    48841 tacatatttg gaaagatatt atcgtagtct agaactttct tatccaatcc ttgtggacag
    48901 tagagaagga caggttgttc ctctacaaag accagattag gacattccat catgtaggca
    48961 gtacggtcgt tagcaaagtc aaggtcgcca actgcttgcc agtttgtgta gtcgttattg
    49021 acagccttgt agagacgaac gaaacctttt ttctccaagt cttgtccgcc gacaatggca
    49081 taatattgac cctgaaagtt aaaaatttgt ggatcgcgga agtggtcagt agagtctgct
    49141 ggctggtcaa tcaagatctt gtcaatcttt gtaatcttac cctccttgtc catcaaagca
    49201 ccgatctggt atgggtgacg gatccagttt ttatcgcgaa catttcctgt ataaaatagg
    49261 aataagttat cgccaaattg catggcagaa ccagagtagg caccgtggct atctaatgga
    49321 gtatctggta aaactttgat tccagtttct ttaaagtgaa tcaaatcatc actttctagc
    49381 tgtgcccaag attttaaacc gtgggctgca ccaaaaggaa aattctggta aaagaggatc
    49441 cacttgccat caaagtaaga aaagccattt gggtcgttga gaagtcctgt ttttggctca
    49501 acatggtaat gagtatgcca tggagattgt gccatatttt cctttatatg ttgaatttct
    49561 tcttgcgtcc aatcttgata aagtctgtaa cgacgctcag ttgtccattc cattcattcc
    49621 tccaaaaatc ttatcacttt taatagtaac tgttttcgat aaaaaatgca agccttttat
    49681 attaaaaaag agaaaaaact gtcaaacgat tatcataaaa taaatacagg aaatcaatca
    49741 aatttttacg aaaatgtgaa agataatgaa ataaaatact ttttaaccaa ggtttcaaac
    49801 ttatttttca aggaattcct gatgaaacag tcaaaaacaa tcaatctaaa gcttgcccac
    49861 taagtggata gaatattttt ttctgcaaaa cgcttgacat atttttaaaa catgataaaa
    49921 taatagtcgt aagggcgaat aaaatcgctt tcaaacaaga acaaaatgtt atataaggag
    49981 atttttgcaa atgaacaatc aggaaattgc aaaaaaagtc atcgatgcct tgggcggacg
    50041 tgaaaatgtc aatagtgttg cccactgtgc gactcgtcta cgtgtcatgg tcaaagatga
    50101 agagaaaatc aataaagaag tgattgagaa cttggaaaaa gttcaaggtg ctttctttaa
    50161 ctcagggcaa taccaaatta tctttggtac aggtacagtt aacaaaatgt acgatgaagt
    50221 tgttgtactt ggcttaccaa catcatctaa ggatgacatg aaagcagaag ttgctaaaca
    50281 agggaactgg ttccaacgtg ctatccgtac tttcggtgat gttttcgttc caatcatccc
    50341 agttatcgta gcgacaggtc tcttcatggg tgtgcgtggt cttttcaacg ctcttgaaat
    50401 gccacttcca ggtgactttg caacttacac acaaatcttg acagatacag ccttcatcat
    50461 cttgccaggt ttggttgtgt ggtcaacctt ccgtgtattt ggtggaaatc ctgccgttgg
    50521 tatcgttctt ggtatgatgc ttgtctctgg ctcacttcca aacgcttggg cagttgctca
    50581 aggtggtgaa gtaacagcga tgaacttctt tggtttcatc cctgttgttg gtttgcaagg
    50641 ttccgttctt ccagccttca tcatcggggt tgtcggagct aaatttgaaa aagctgtccg
    50701 caaggttgtt ccagatgtca ttgacctctt ggtaacacca ttcgtgacac ttttggtcat
    50761 gtctatcctt ggactctttg tcattggacc agttttccac gttgttgaaa actacatcct
    50821 tattgctaca aaagcgattc ttagcatgcc atttggtctt ggtggtttct tgattggtgg
    50881 ggttcaccaa ttgatcgtcg tgtcaggtgt gcaccacatc ttcaacttgc ttgaagtgca
    50941 attacttgct gctgaccatg ctaacccatt caacgctatc atcacagctg ctatgacagc
    51001 tcaaggtgct gctactgttg cggttggtgt taaaacaaaa aatccaaaac tgaaaacact
    51061 tgctttcccg gctgctcttt ctgccttcct aggtattaca gagcctgcta tcttcggggt
    51121 gaacttgcgc ttccgtaaac cattcttcct ttcattgatt gctggtgcaa tcggtggtgg
    51181 attggcttct atccttggac ttgctggtac tggtaatggt atcaccatca tccctggtac
    51241 aatgctttat gttggtaacg gacaacttcc acaatacctt cttatggtag ctgtatcatt
    51301 tgcccttggt tttgctctta cttacatgtt tggttacgaa gatgaagtag acgcaactgc
    51361 agctgcaaaa caagctgaag tggctgaaga aaaagaagaa gttgcgccag cagctcttca
    51421 aaatgaaaca cttgtaactc ctatcgtcgg tgatgttgtc gctcttgctg atgtcaatga
    51481 cccagtcttc tcaagtggag ctatgggaca aggtatcgct gtgaaaccaa gccaaggcgt
    51541 ggtctatgca ccagctgatg ctgaagtttc aattgccttt ccaacagggc acgcttttgg
    51601 tttgaaaaca agaaatggtg ctgaagtttt gattcacgtt ggtattgaca ctgtatctat
    51661 gaacggtgac ggttttgaag caaaagttgc tcaaggtaat aaggtgaaag ctggcgatgt
    51721 tcttggaaca tttgactcaa acaaaatcgc tgcagctgga cttgatgata caacaatggt
    51781 tatcgttaca aatacagctg actacgcttc agtagctcca gtcgcaacag gttcagttgc
    51841 gaagggggat gctgtgatcg aagtgaaaat ctaatcaatc ctctctaatg tgaaaacgaa
    51901 caaatgacat gtttgttcgt ttttattaga tagtaagatt tacagaggaa aatctaaaaa
    51961 atagagacat ttagactttc gaagtatgct ataataaaga aaataaaaac aagaggttta
    52021 tcatgacaaa attatatgga agcttggaag cgggcggtac aaagtttgtc tgtgctgtcg
    52081 gtgatgaaaa ctttaacgtc gtagaaaaaa cacaatttcc aacaacaact ccaatcgaaa
    52141 caatcgataa aaccattgag ttcttctcaa aattcgataa ccttgctggt cttgcagttg
    52201 gttcatttgg gccgattgat attgacaaaa actcaaaaac ttatggcttt atcacgacga
    52261 ctccaaaacc aaactgggca aatgtggact tgcttggtgc ccttcgtcgc gccctaaacg
    52321 tgccaatgta cttcacaaca gacgtaaaca gctctgctta cggtgaagtg gttgcccgta
    52381 acaatgctgg tggtcgtatc gaaaacttgg tttactacac aatcggtaca ggtatcggtg
    52441 caggcgtcat ccaacgtggt gagtttatcg gtggtgtggg tcaccctgaa atgggtcatt
    52501 attatgttgc tagacaccca atggatattg aaaaagagtt taagggtgtt tgtcctttcc
    52561 ataagggatg tctagaaggt tatgcagctg gtccaagttt ggaagctcgt acaggtgtac
    52621 gtggggaaac tattgaactc aacaaccctg tttgggatgt tcaagcctac tatatcgctc
    52681 aagctgcggt taatgcgaca gtgactttcc gcccagacgt gattgtcttt ggtggagggg
    52741 tcatggctca acaacatatg ctggaccgtg tccgtgagaa atttacatct cttcttaatg
    52801 gttacctacc agtaccagat gtgcgtgact atatcgtgac gccagcagtc gcaggaaatg
    52861 gttctgccac acttgggaac tttgttcttg caaaagaagt ttcaaaataa agcacaaaat
    52921 ccgtttggtt tcccaagcgg attttgtggt tgaaaacaat atttttgagc ctttccttaa
    52981 gtgattacgg acggtagcga ctttcttcga aattccatac ctaaactttg agcctagtgt
    53041 ctcaaagttt ccgaatacct gaaaccatta gatttcaggt gtttctatca cggcggaaag
    53101 gctaggtaag tcctcgcctc actatcgaaa aatatgcatg atttccatac caaagtatat
    53161 ttagtatcaa gctatagtta atctacgctt taaaaatcca cttgggaaac caaacggatt
    53221 ttttacgtgt caaagcattt gccagaaaaa gtcaataata taggtcagac cgtaggtata
    53281 aaccacgagg gtaaagggtt tggtcagaat gatgatggtc atgtagcgct tgaaactcat
    53341 cttggtcagg gcagccagca tacagagaaa gtcagctggg ctaatgggcc aaatcatcat
    53401 aaaaataaag aagcggtcaa aacgattgcc cttatctagc cagccgatgt acttgtcgta
    53461 ggtgcgcttg ctgacgacag actggacaaa ggcagctccg tataggcgca ctagataaaa
    53521 gataatggca cagccaatca cgatgccgat atagttgtag atagtcccga tgatgtgccc
    53581 gtagataaag accccagcca ccgaggtcaa ggcccctgga atgataggga cgacagtctg
    53641 taaaatctgt aaaaagataa agagaggtgg accccagatg cctgcctgct ggataaaggc
    53701 agagagggtt tccttggatt gtaaaatccc agcctgataa gcccaaatac agaaaatcaa
    53761 actcccaacc ccaccgacaa tcgatgagat attgataact cgctgcagaa ggggagaaac
    53821 agctttcatt tgtttatcct gtgacatgta aactcctcat agatagtata tttctactat
    53881 accatatttt ggaggagaaa gggggaatga gtcttttttg ataaggaata gaaagtaaat
    53941 agcccttcga gacttagaat aggtctgtca actaaaggtt atatgcattc taggtttcga
    54001 ataatcgcaa ttacataaat ttaaaagcat tctaagtttc gaatagctta tctgagataa
    54061 ttttgaggca ttcgcgcttt cgaatagtca ttttccctaa agtttagatg tattctgaag
    54121 ttagaaagac taaaatctaa aagtagtaag agtctctctc tgatggacgt aatttatggc
    54181 tagtatgaat cctttgaatt gttagttaat tttaatatta atcagttctg aaataattac
    54241 taaatatagt tagatagtga attaattatt gctaaatttc aagttcaagt tagtcatcca
    54301 gaagtcttct ctgggggact tgtagttcaa gcatttttta ggatagttgt taatccgctt
    54361 ttcgatgaat gcgacttcct tggtagtcgt tttcttagtt cccttaggct taggtaacca
    54421 tttacgaatg aacctgttgt gatttttatt agatcctata gtggtgtgca taata
//
LOCUS       DAVKBC010000008        50999 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVKBC010000008 DAVKBC010000000
VERSION     DAVKBC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.008"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            24..194
                     /locus_tag="VWX64_000568"
     CDS             24..194
                     /locus_tag="VWX64_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190098.1"
                     /translation="MKKNRGIQKLAILVLLDVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            644..2659
                     /locus_tag="VWX64_000569"
     CDS             644..2659
                     /locus_tag="VWX64_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9190099.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            2661..3293
                     /locus_tag="VWX64_000570"
     CDS             2661..3293
                     /locus_tag="VWX64_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190100.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSDSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVTLAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4221..4634)
                     /gene="ndk"
                     /locus_tag="VWX64_000571"
     CDS             complement(4221..4634)
                     /gene="ndk"
                     /locus_tag="VWX64_000571"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU9190101.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(4745..8422)
                     /gene="rpoC"
                     /locus_tag="VWX64_000572"
     CDS             complement(4745..8422)
                     /gene="rpoC"
                     /locus_tag="VWX64_000572"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU9190102.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(8455..12066)
                     /gene="rpoB"
                     /locus_tag="VWX64_000573"
     CDS             complement(8455..12066)
                     /gene="rpoB"
                     /locus_tag="VWX64_000573"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9190103.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12482..12552
                     /locus_tag="VWX64_000574"
     tRNA            12482..12552
                     /locus_tag="VWX64_000574"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12514..12516,aa:Cys,seq:gca)
     gene            complement(12750..14081)
                     /locus_tag="VWX64_000575"
     CDS             complement(12750..14081)
                     /locus_tag="VWX64_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU9190104.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(14372..15196)
                     /gene="endA"
                     /locus_tag="VWX64_000576"
     CDS             complement(14372..15196)
                     /gene="endA"
                     /locus_tag="VWX64_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU9190105.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     GPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15235..15423)
                     /locus_tag="VWX64_000577"
     CDS             complement(15235..15423)
                     /locus_tag="VWX64_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9190106.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(15416..16699)
                     /gene="murA"
                     /locus_tag="VWX64_000578"
     CDS             complement(15416..16699)
                     /gene="murA"
                     /locus_tag="VWX64_000578"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9190107.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(16723..16953)
                     /locus_tag="VWX64_000579"
     CDS             complement(16723..16953)
                     /locus_tag="VWX64_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU9190108.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(17011..18048)
                     /locus_tag="VWX64_000580"
     CDS             complement(17011..18048)
                     /locus_tag="VWX64_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU9190109.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(18032..18520)
                     /gene="coaD"
                     /locus_tag="VWX64_000581"
     CDS             complement(18032..18520)
                     /gene="coaD"
                     /locus_tag="VWX64_000581"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU9190110.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(18510..19049)
                     /gene="rsmD"
                     /locus_tag="VWX64_000582"
     CDS             complement(18510..19049)
                     /gene="rsmD"
                     /locus_tag="VWX64_000582"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU9190111.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19114..20106)
                     /locus_tag="VWX64_000583"
     CDS             complement(19114..20106)
                     /locus_tag="VWX64_000583"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU9190112.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20218..20901)
                     /locus_tag="VWX64_000584"
     CDS             complement(20218..20901)
                     /locus_tag="VWX64_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU9190113.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLGFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(20957..21697)
                     /locus_tag="VWX64_000585"
     CDS             complement(20957..21697)
                     /locus_tag="VWX64_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU9190114.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            21731..22009
                     /locus_tag="VWX64_000586"
     CDS             21731..22009
                     /locus_tag="VWX64_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU9190115.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22087..23013
                     /gene="yidC"
                     /locus_tag="VWX64_000587"
     CDS             22087..23013
                     /gene="yidC"
                     /locus_tag="VWX64_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9190116.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23088..23882)
                     /gene="pflA"
                     /locus_tag="VWX64_000588"
     CDS             complement(23088..23882)
                     /gene="pflA"
                     /locus_tag="VWX64_000588"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU9190117.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(24008..25258)
                     /locus_tag="VWX64_000589"
     CDS             complement(24008..25258)
                     /locus_tag="VWX64_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU9190118.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLIRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25325..26152)
                     /gene="purR"
                     /locus_tag="VWX64_000590"
     CDS             complement(25325..26152)
                     /gene="purR"
                     /locus_tag="VWX64_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU9190119.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(26419..27360)
                     /locus_tag="VWX64_000591"
     CDS             complement(26419..27360)
                     /locus_tag="VWX64_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU9190120.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(27350..28606)
                     /locus_tag="VWX64_000592"
     CDS             complement(27350..28606)
                     /locus_tag="VWX64_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU9190121.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(28608..29270)
                     /locus_tag="VWX64_000593"
     CDS             complement(28608..29270)
                     /locus_tag="VWX64_000593"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU9190122.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(29233..29889)
                     /locus_tag="VWX64_000594"
     CDS             complement(29233..29889)
                     /locus_tag="VWX64_000594"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU9190123.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(29900..30778)
                     /gene="rsgA"
                     /locus_tag="VWX64_000595"
     CDS             complement(29900..30778)
                     /gene="rsgA"
                     /locus_tag="VWX64_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU9190124.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(30780..31652)
                     /gene="rsmA"
                     /locus_tag="VWX64_000596"
     CDS             complement(30780..31652)
                     /gene="rsmA"
                     /locus_tag="VWX64_000596"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU9190125.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFIHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(31783..32091)
                     /locus_tag="VWX64_000597"
     CDS             complement(31783..32091)
                     /locus_tag="VWX64_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190126.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(32084..32725)
                     /locus_tag="VWX64_000598"
     CDS             complement(32084..32725)
                     /locus_tag="VWX64_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190127.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVSLAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(32727..34757)
                     /locus_tag="VWX64_000599"
     CDS             complement(32727..34757)
                     /locus_tag="VWX64_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9190128.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQGLFTDYL
                     QNFSSESVEVTSQKYYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(35026..35925)
                     /locus_tag="VWX64_000600"
     CDS             complement(35026..35925)
                     /locus_tag="VWX64_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9190129.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIAHRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQGYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(35997..36557)
                     /gene="rnmV"
                     /locus_tag="VWX64_000601"
     CDS             complement(35997..36557)
                     /gene="rnmV"
                     /locus_tag="VWX64_000601"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU9190130.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLVGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(36557..37330)
                     /locus_tag="VWX64_000602"
     CDS             complement(36557..37330)
                     /locus_tag="VWX64_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU9190131.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKNLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(37635..38534)
                     /locus_tag="VWX64_000603"
     CDS             complement(37635..38534)
                     /locus_tag="VWX64_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU9190132.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKEKV
                     KVAILQANGSALDGATINVAGYGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATP
                     EYKLETTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESA
                     KNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETI
                     GVQAIVMVTVPKRPVAPNTAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAAL
                     ASLGLVVATSGFALLGRKTRRRK"
     gene            complement(38818..38952)
                     /gene="rpmH"
                     /locus_tag="VWX64_000604"
     CDS             complement(38818..38952)
                     /gene="rpmH"
                     /locus_tag="VWX64_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU9190133.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            39360..40313
                     /locus_tag="VWX64_000605"
     CDS             39360..40313
                     /locus_tag="VWX64_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEU9190134.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            complement(40342..41556)
                     /locus_tag="VWX64_000606"
     CDS             complement(40342..41556)
                     /locus_tag="VWX64_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9190135.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(41712..42005)
                     /locus_tag="VWX64_000607"
     CDS             complement(41712..42005)
                     /locus_tag="VWX64_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190136.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            42167..42619
                     /locus_tag="VWX64_000608"
     CDS             42167..42619
                     /locus_tag="VWX64_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU9190137.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(42654..44042)
                     /locus_tag="VWX64_000609"
     CDS             complement(42654..44042)
                     /locus_tag="VWX64_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9190138.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            44108..45070
                     /locus_tag="VWX64_000610"
     CDS             44108..45070
                     /locus_tag="VWX64_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU9190139.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(45067..45213)
                     /locus_tag="VWX64_000611"
     CDS             complement(45067..45213)
                     /locus_tag="VWX64_000611"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190140.1"
                     /translation="MNTIERTRRLVKGCATHCFEVADETDEVSNHTYGKATLTWFAEI
                     FEEY"
     gene            complement(45277..46287)
                     /gene="ccpA"
                     /locus_tag="VWX64_000612"
     CDS             complement(45277..46287)
                     /gene="ccpA"
                     /locus_tag="VWX64_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU9190141.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(46712..47311)
                     /locus_tag="VWX64_000613"
     CDS             complement(46712..47311)
                     /locus_tag="VWX64_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9190142.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQTKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(47313..48410)
                     /locus_tag="VWX64_000614"
     CDS             complement(47313..48410)
                     /locus_tag="VWX64_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9190143.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVIGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESTAAMILLELVTNIIKHAKAFKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(48410..49147)
                     /locus_tag="VWX64_000615"
     CDS             complement(48410..49147)
                     /locus_tag="VWX64_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190144.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSSMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLASWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELIKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(49149..50033)
                     /locus_tag="VWX64_000616"
     CDS             complement(49149..50033)
                     /locus_tag="VWX64_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190145.1"
                     /translation="MNMIKVQGLHKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLSQENVIVQKLKVKELIAFFQSIY
                     PNPLSEQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTREADSFWQLLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(50020..50214)
                     /locus_tag="VWX64_000617"
     CDS             complement(50020..50214)
                     /locus_tag="VWX64_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190146.1"
                     /translation="MKKATIYFFIGLSLLVWLVEMFTGWFAQTFLHQFIRGAWGLGFM
                     IFIAFPMGKELLEGEYHEHD"
     gene            complement(50211..50417)
                     /locus_tag="VWX64_000618"
     CDS             complement(50211..50417)
                     /locus_tag="VWX64_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190147.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDENFYHFPWEVFAG
                     FGMMSWLVREGLKLVRDVKKEFEK"
BASE COUNT        14793 a        11525 c         9736 g        14945 t
ORIGIN      
        1 ggaaaaagaa aggggtttca cgaatgaaga aaaatcgtgg aattcaaaaa ttagctatat
       61 tagtattact agatgttttt atgtttagta acacaattcc ttaccaacag tttattcaga
      121 agaatagaca attggagatt cgagtgcaat cacaaaagaa gtccaatggt cttgatgttg
      181 ggaaggctga ttgatttcgt attactttaa aattcaacta tttagagaaa ggtattctga
      241 tgagagcttg taacaatacc agatagatat aagaatggag atgtttgata aaatgctttc
      301 atagctaacc aactgttgaa aattatgagt tacaaaatct aaagtattta agattggttt
      361 ataaaattag gtctctgcct gtagaaagga acgtgcagtt agaaaggagg aaaaaatagg
      421 atactataat tcagactgag atttctaatt aaaatatgta gttgcatttc gctcattttc
      481 ataatatttc attcagagga gtaataatat gttaaaattt acatttgatg cgggatggta
      541 aagaataatt gaagaagatt cttttatcaa tagtttagta aacttgttag tttatagagg
      601 gtaggcgtat ttctgccctc tgttttagaa taaggaatgc actatgaaaa aattatttat
      661 actcatatcc aacctgcttg ctagtttgtt ctttgtttgg gtatttacca tttggactga
      721 tacatatgtc tcctattatt accccaacgt tgttgtacat gattcttccc ctgaaacaac
      781 ttttcagcat gttgctacac gcttggaaaa actagcagaa gaaacagata gctttattgc
      841 gattcaacac caagatccta actcagaagg tactacagtt ttttcttata caacctttgg
      901 ggacggaaag ttgcctgatg ggcttcagga aaaaaaacta gaagatgctc aaagtagtag
      961 tgttgaaaca aactattttg tattcgatgg acacctagat attcacttgc taagggagga
     1021 gctaagtcaa cttggcttga ctaatatgaa cctgacaatt ccatctaaac tatctacgtt
     1081 aatggctatc tttagtaacg gatttcagtt aatcagtcta ttgattttca tcttaacctt
     1141 tgtagcactg actttaatta gtcaaattag ccaattacgg tcgtcgggca ttcgcctcat
     1201 ttcaggagag aaacggtggt ccattttcct tagaccagtt ggtgaggatt tgaaagggat
     1261 agctgttggt ttcagtttag ctggcgtgct cgccattctt atgcaaaaaa ttctgtcgct
     1321 tccaacgcaa tccctaatga ccataggagc aggcttgctc agttataatc tcatcttgtt
     1381 gtcgatctcc ctgtttttcg ctcaactctt cgcagttggg ataaaaaaga tacacctgat
     1441 gcagattata aaagggcaag tgcctgtcag aggaatcatt agtttgattt taatcggtca
     1501 actattagcg attattattg taacgctggg aatagggagt agcttaaagt attcccaagc
     1561 ctggcaacag catcggattg gacaagaggt ttggagtcag gaaaggcaac tgattaccct
     1621 atcaatcagc cgtgaaggaa cgagtcctgg ttttgatgaa caagctcaaa ggaaactcag
     1681 aacttggtat caattgatgg atctggctgt ttcagaacaa aaggctttct tatctagaca
     1741 ccagttaatt gaccgtactt tgcaaaatgg catggcttcc tccaaaaact tgataacctc
     1801 tacagaatgg cacgattaca acccgaatgg caatgtcctt atcgtcacac cgcaatactt
     1861 ggagcgtcaa aacattcctg tagatacaac tattgagcaa aagatgaatc accttgatgt
     1921 aggggagttt gtcttattgc tgcctgaaca cctccgttca gaggaagaac attataaatc
     1981 tgtttttgaa gacgacttaa ccagtcgcat gtctagtcaa gatgaacgac agcaaatgac
     2041 tgctacggta ggttatttag aatcaggtca ggatcgtttt gtgtataata cgacccctat
     2101 ttcttaccag cagtttttga aagatccaat catcattgtt ataacacccc aatcaactgg
     2161 tccacagtcc attttgtttt ggatagacgc agtacagaac tacgttctct ttaatcaatt
     2221 gtctgatgcc caggagctta tccagagaca aggcattgaa aattgggtct cagaaatgca
     2281 aacaggttac cacaactaca tcacattatt ggataatatc cagagggaac gttgggtaat
     2341 gctagcagga gctgtgcttg ggattgcaac ttcaatcttg ttgtttaaca ctatgaatag
     2401 gctctacttt gaagaattta gacgtgccat ttttatcaaa cgcattgcag gtctcaggtt
     2461 cttagaaatc catcgcactt atctctttgc tcaactgggt gtgtttttac tgggatttgt
     2521 tgcgagtgta tttcttcagg tagagatagg agttgctttc ttagtcttgt tactctttac
     2581 tggtctatct cttttacagt tacatgtcca aatgcagaaa gaaaacaaga tgtccattct
     2641 tgttttgaag ggaggttaat atgattgaac ttaaacaggt gagtaaatct tttggagaac
     2701 gagagttatt ttcgaatctt tcaatgacat ttgaggctgg aaaagtctat gccttaattg
     2761 gttcaagtga tagcggaaaa acaaccttga tgaacatgat tgggaaatta gaaccttatg
     2821 atgggacgat tttttaccga ggtaaagact tggccaatta taaatcgagt gattttttcc
     2881 gtcacgaatt gggctacctc ttccagaact ttggcttaat tgaaaaccaa agtattgaag
     2941 aaaaccttaa gctaggtctc attggtcaaa agttgagtcg gtcggaacag cggttgaggc
     3001 agaagcaggc tttagaacag gtcggcctgg cttatcttga cctagataag cgcatctttg
     3061 agttatcggg cggagaatcg caacgggtta ccttggcaaa aattatctta aagaatccac
     3121 cctttattct ggcagatgag ccaacagctt caatagaccc agcaacctct cagttgatta
     3181 tggagatttt gctatctctt cgagatgata ataggctaat cattatcgca acacataatc
     3241 cggcaatttg ggagatggct gatgaagtgt tcacgatgga tcatctgaaa taaaaatcct
     3301 tgtttttaat tgcacgatga gttactgaaa tattatcatg aatcaagaat tggagttaat
     3361 ttagaattgt actttattaa tattgaggta actttttctt gataaaggaa gaaataatgg
     3421 agaggaagtt agaatgaaaa aattcgacaa ttatattatt gagaagcctt gcgattctaa
     3481 ttcagataaa ctgcaaaaaa tcttaataat tgaaagtttg gtagatgata ttttgcaatt
     3541 ttctctcaga atcaataata gtgtaggaga gattttcctc ctacaaccgt tttaaaagaa
     3601 aactatcttt attccatgtt attttgagga agatattgtg aaagtcaaag atgatgataa
     3661 agttgagtgg aatttgttag aatttcaaaa atttagagca tttttggctt agtaatctgt
     3721 gttgaaggct caaaacctat ggtaaaaaag tagctttgaa aacgtattgc ctccaaagat
     3781 ttagttaaat aatgatttaa cacaaaaaga aattattgaa gttctggaaa gatgttgttt
     3841 cagtattgag aaaaggtggg aaaaacttgc gattttcaca gagaaaggaa gaaaaagtat
     3901 agaaatatag tcaattgaaa caagaacagg ataaaagaac cttttgtgcc atatttttct
     3961 cctttcgctt tacaattgga ttgaacacct ttattgtatc gcgtttggag tttttttggt
     4021 ataaccttcg acgcgcaccc gcatagcggg tgtttttttg tctcgcacct aacggagcga
     4081 gacaaactaa tagtcactta atcaaaaaac gcaccatatc aaaaactaaa aagtttgata
     4141 tcatgcgtca tgtcttaaac taattgacta tactttctat tcaaatgagc ttttaaccaa
     4201 ttgattgagc caatccactc ttaaaaccaa agagcaattt ctcgcttagc tgactcttct
     4261 gaatctgaac catgtacaac attttggata atctcatttt ctccagcagc ttttgcaaaa
     4321 tcacctcgaa tagtgcctgg taaagcttct tctggacgag ttgcacccat catggtccgc
     4381 caagtttcga ttactttggg accagaaatg acacccacaa gaactggacc tgaagtcatg
     4441 aattcacgaa tcggtgggta aaaactctga ccaaccaagt cctgatagtg ctggtcaatc
     4501 aactcttctg aaacctgtga acgaaactcc aatttttcga ttgtaaatcc acgttgttcg
     4561 atgcgcttta acacttcacc cactagccct ctttttacac catctggttt gatgataaag
     4621 aatgtttgtt ccatacccgt ctcctttgtc agcttctttc ttttatttta ccacatttcg
     4681 tggaaaaatg gagaaagttt tcagaagaga gaatgagaga accctcgggt tctctcattc
     4741 tctcttattc tactgtttct tccacagttt caacggcagt atccacaact acttctgttg
     4801 tttcttcatt tccttcttcc tctactggag gattaaggta ttcttcttcg ttgacagcat
     4861 gtggttcaag gttacggtaa cgggccatac cagtaccagc tgggatgatc ttaccgatga
     4921 taacattttc tttaagtcca aggagatggt ctttcttacc acggatagct gcgtcagtaa
     4981 ggacacgagt tgtttcctgg aaggaagccg ctgacaagaa actgtttgtt tcaagtgagg
     5041 ctttggtaat tcccataagg actgggcgac ctgtcgctgg aactccacct gcgataagga
     5101 catctttgtt ggcatctgta aagtcattga tatccatgag ggtacccatg agaagatctg
     5161 tatcacctgg atccatgaca cggactttac ggatcatttg acgaaccatt acctcgatgt
     5221 gtttgtcacc gatttctacc ccttggctac ggtaaacttt ttgtacttca ccgagaaggt
     5281 acgtttcaac tgacaagaca tcacgaactg caaggagacg ttttggttgg atagaacctt
     5341 ctgtcagagc agcaccacgc gctacttgtc ccccaacttc gacacgcata cgagctgtaa
     5401 atggaacgac atattcacct tcgccagttt cacccttaac aaagactttc ttggtacgag
     5461 ttgatgcatc ttcttcgata gcagtaactt gtcctttaac ctctgtaata accgcttccc
     5521 ctttaggatt gcgggcttca aagatttctt ggacacgagg aagaccctga gtgatatcgg
     5581 tatttgaggc aaccccacct gtgtggaagg tacgcattgt aagctgtgta ccaggttccc
     5641 cgatagattg ggcagcgatt gtaccaactg cttcaccaac ttcaaccgca tcaccagtcg
     5701 ccaagttgat accgtaacag tgacggcaga caccgtgacg agtgttacat gtaaatacag
     5761 aacggatagt cacttcttcc acaccagcat tgacaatttc acgcgccttg tcttctgtaa
     5821 tcaattcatt tggaccaata atcactgcac cagtttctgg atgtttaaca gttttcttag
     5881 tgtaacgacc gttgagacgc tcttcgagag actcgatcat ctcttttcct tctgcgatag
     5941 aacggatcaa gagaccacgg tcagttccac agtcgtcctc acggatgata acgtcttggg
     6001 caacgtcgac caaacgacga gtcaagtaac ctgagtcggc tgtcttaagg gccgtatcgg
     6061 tcataccttt acgagcaccg tgagttgaga agaacatttc caataccgac aaaccttcgc
     6121 ggaagtttga aaggattggc aattccatga tacgtccatt cggagcagcc atcagaccac
     6181 gcataccggc aagctgtgag aagtttgaga tgttaccacg ggctccagag tccatcatca
     6241 taacgattgg gttcttagga tcttgattag caatcaagcg tttctcaagt ttttcacggg
     6301 cagcacgcca ttcagctgta acagcattgt aacgctcgtc atctgtgatc ataccacgac
     6361 ggaattgttt ggtgatttgt tcgacacgtt tgtgtgattc ttcaatgatt tcagccttgt
     6421 catcaacgac tgggatatcg gcaataccca ctgtcaatcc tgcaagagtt gagtggtggt
     6481 aaccgaggtt cttcatgcgg tcaagtaggg cagaagtttc tgtcgtacgg aaacgtttga
     6541 agatttcagc gatgatattt ccgaggtttt tcttcttgaa tggagggttg agctcaagat
     6601 tgctgatagc ttccttgata tctccaccaa gtggcaagaa gtatttagct ggaacacctt
     6661 ctgtcaagtt ggcattgttt ggttcttgca agtatggtag cccctctggc atgatatcgt
     6721 tgaagagaat tttaccaact gttgtaagca agaccttatg tctttgctct tctgtccaag
     6781 gcttgttgag gctgtctgtt gcgataccaa cacgtgagtg gaggtgaaca taaccattgc
     6841 ggtaagccat aaccgcttcg tcacggtctt tgaagaccat tccttcacct tcgcgaccag
     6901 cttcttccat ggtcaagtag tagttaccca aaaccatgtc ctgagatgga gtaactaccg
     6961 gtttcccatc tttcgggttc aagatgtgct cagcagctag catgaggata cgagcttctg
     7021 cttgtgcttc ttctgaaagt ggtacgtgga tggccatttg gtccccgtca aagtcagcat
     7081 tgtaggcttc acagacaagt gggtgcaagc gaagagcctt accatcaatc aagactggct
     7141 cgaaggcttg gatacccaaa cggtgaaggg tcggtgcgcg gttcaaaagc actgggtgtt
     7201 ctttaatcac ttcttcaagg atatcccaga tacgctcatc tccgcgttcc accaagcgtt
     7261 tagctgcttt gacgttttgc acgatatcac gggcaacgat ttcacgcatg acaaatggtt
     7321 taaagagttc aatcgccatt tcacgtggca caccacattg gtacatctta agagttggac
     7381 caacggcgat aacggaacgt cctgagaagt caacacgttt accgagcaag ttttgacgga
     7441 agcgtccttg tttaccttta agcatgtggc tcaatgattt caatggacgg ctacctggtc
     7501 ctgtgattgg acgaccacga cgaccattgt caatcaaagc gtcaactgct tcttgaagca
     7561 tacgcttctc attttgaacg atgatacctg gtgcatttaa ctcaagcaaa cgagccaaac
     7621 ggttgttacg gttgataaca cggcggtaaa ggtcattcaa gtcagatgag gcaaaacggc
     7681 caccatccaa ctgcaacatt ggacgaagat ctggtgggat aaccggaagg atgttaagaa
     7741 tcatccattc aggtttgttt ccagacttgt aaaaggcatc caaaacatcc aaacgacgga
     7801 tggctttgac acgtttttgt ccagtagcag ttttcaattc ttctttgagt tcagcaattt
     7861 ctttttcaag atctacttgc ttcaaaaggt cttggatggc ttccgcaccc atcttagcaa
     7921 caaatgaacc ataaccatat tcacgcaagc gctctcggta ttcgcgctct gtcatgatag
     7981 acttgtgctc aagtggtgta tccttaggat caatcaccac ataagccgca aagtagataa
     8041 cttcctcgag ggcacgaggg ctcatatcaa gggtcaagcc catacggctt ggaatcccct
     8101 tgaagtacca gatgtgagat acaggagctt tcaattcgat atgtcccata cgctcacgac
     8161 gaactttcgt acgcgttact tcaaccccac agcggtcaca aacaattcct ctgtaacgaa
     8221 tgcgtttgta cttaccacaa gcacattccc agtcttttgt aggaccaaag atcacttcat
     8281 caaagagtcc ttcacgttct ggtttcaagg tacggtaatt gattgtttca ggttttttga
     8341 cttctccata agaccatgaa cggactttac ttggagaagc tagggtgatt tgcatacttt
     8401 taaaacgatt tacatcaacc actatttctt ccctttctat tctaagtgaa ctgcttattc
     8461 ttgttcagca gcttcttctg ttgcttccgc ttttgttgct ttctcagctt cttcagcttc
     8521 aaaggctgct ttagcctctt gggctgcttt ttcgcgggct ttttcaaggt catctacgtg
     8581 gatgacatct tcgtccattc cttcatccaa gtcgcgaagt tccacttctt ggtcatcttc
     8641 gtctaggaca cgcatgtcaa gaccaagaga ttgcaattct ttgacaagaa ctcggaagga
     8701 ttctggaaca cctggttttg gaattggttt gccttttgta atagcttcat aggctttcaa
     8761 acgtccgttg atatcgtcag acttgtaagt caagatttct tgaaggacat ttgacgcacc
     8821 gtaggcttca agagcccaaa cctccatctc accgaaacgt tgtccaccaa actgagcttt
     8881 acctccgagt ggttgttggg taacagttga ataaggtccg actgaacgcg cgtgcaattt
     8941 atcgtcaacc atgtggtgga gtttgatcat gtacatgact ccaacagaaa cacggttatc
     9001 aaatggttca cctgtacgtc catcgtaaag gattgtcttg gcatcgctat ccatacctgc
     9061 ttctttaaca gttgaccaaa gatcttcaga acttgctcca tcaaagactg gtgtcgcaat
     9121 gtgaatacca agagtacgag ctgccatacc aaggtgaagc tccataacct gaccgatatt
     9181 catacgtgat ggcaccccaa gtgggttcaa catgatgtcg actggagttc cgtctggaag
     9241 gtaaggcatg tcttctacag gaacgatacg agagacaacc cctttgtttc cgtgacgtcc
     9301 ggccatttta tctccgacct taatcttacg tttttgagcg atgtaaacac gaaccaacat
     9361 gttaacacct gattgcaact catctccatt tacacgtgta aagatcttaa catcacgaac
     9421 gacaccatcg gcaccgtgtg gtacacgaag agaagtatca cgcacttcac gagacttgtc
     9481 tccaaagata gcgtgcaaga gacgttcttc agctgaaaga tctttctcac ccttaggtgt
     9541 tactttacct acaagaatat caccttcttt aacctcagca ccaatacgga taatccccat
     9601 ttcgtcaagg tctttgaggg catcttcacc aacgtttgga atttcgcgag tgatttcttc
     9661 aggcccaagc tttgtatcgc gcgtttctga ttcgtattct tcaaggtgaa cagatgtgta
     9721 gacatcgtcc ttcaccaagc gttcgctcat gataacggca tcctcgaagt tgtaaccttc
     9781 ccaagtcatg taggcaacga ttgggttttg tccaagcgcc atttctccat tttccataga
     9841 aggtccgtca gcgatgaaat cgcctttttc aacgacatca ccaactttta cgagagtgcg
     9901 ttggttgtaa gcagtacctg agtttgaacg acggaatttt tggatgtggt aaacatccaa
     9961 tgaaccatct tcacgacgaa cttctacctt gtcagcatct gcgtaagtaa ctttaccatc
    10021 atactgagca atcacagccg caccagaatc gtgggctgct tggtattcca taccagtacc
    10081 aacgtaaggt gcctgaggat taatcaatgg cacagcctga cgttgcatat tggctcccat
    10141 gagggcacgg ttggagtcat cgttttccaa gaaaggaata catgctgtcg caacggcaac
    10201 tacctgtttt ggtgaaacgt ccatgtagtc aacaatatta gctggatact cttggttgac
    10261 cccttggtga cgtcccatga caatcttctc agcaaaggtt ccatcttcat tcagacgaga
    10321 gttagcctga gctacagtat attcatcttc ttcatcagct gtcaaccaaa caatttcgtt
    10381 cgtgacaaca cctgtttcac ggtcaacctt acggtatggt gtttgaacaa aaccatattt
    10441 gttcaagtgt ccgtaagatg acaagttatt gatcaaaccg atgttaggtc cttcaggtgt
    10501 ctcgattgga cacatacgac catagtgagt gtagtgcacg tcacgtactt catatccggc
    10561 acggtcacga gtcaaaccac caggtcctaa ggctgacaaa cggcgtttgt gagacaactc
    10621 agaaagcggg ttgtgttggt ccatgaactg tgacaactgt gatgaaccaa agaattcttt
    10681 aaccgcagct gttacaggac ggatattgat aatttgttgt ggtgtcaaga cttcattgtc
    10741 ctgaacagac atacgttcac ggacattacg ttccatacga gaaagtccca aacgtacttg
    10801 gttggcaagc aattcaccaa ccgcacggat acgacgattt ccaaggtggt cgatatcatc
    10861 tacacggcca agtccttcag ccaagttgag gaagtagctc atctcagcaa ggatatctgc
    10921 aggagtcacc gtacgaacct tgtcatctgg gttagcatta ccaatgatcg ttacgacgcg
    10981 atctggatca gttggagcaa caaccttgaa tttttgaaga acaacaggct cagtcacaac
    11041 ggctgcatcg tttgggatgt agacaatctt gttcaagtcg ccatccaaat ggctttcaat
    11101 gctttcaatc acgctacgag tcataatcgt accagcttct accaagattt ctccagtttc
    11161 agggtctacc aatggctctg caatggtttg gttgagcaaa cgtgttttaa cattgagttt
    11221 tttattgatt ttgtaacgac caactgctgc caagtcatag cgacgtgggt caaagaagcg
    11281 agccacaagc aagctacgtg agctttcagc cgtcttaggc tcacctggac gaaggcgttc
    11341 gtaaatttct ttcaaggctt cgtctgtacg agagtccatt ggattcttgt ggatatcttt
    11401 ttcaacagtg ttgcgaacca attcgctgtc accaaaaata tcaaagattt catcatcacc
    11461 tgagaaacca agagcacgaa ccaaggttgt aaatggaatc ttacgagtac ggtcgatacg
    11521 agtgtaggtg atatcttttg agtcgctttc aagttccaac caagctccac ggttagggat
    11581 aacagttgaa ccatagccca ccttaccatt tttgtctact ttgtcgttaa agtaaacacc
    11641 tggtgagcgg accaactgag aaacgataat acgttcacca ccattgatga tgaaagtacc
    11701 catttctgtc atgattggga aatcaccaaa gaaaacttct tgggtcttga tttcgcctgt
    11761 ttctttattg atcaagcgga aggttacaaa aattggtgct gagtagctag catcgtggat
    11821 acgagcttct tctagcgtgt attttggttc cttgatttca tatccaacaa attccaactc
    11881 cattgtgtct gtgaagtttg aaattggcaa tacatcttca aacacttcct taagaccgtg
    11941 gtctaggaaa gctttgaatg agtcagtttg aatttcaatc aaatttggta agtcaagaac
    12001 ttctttgatt cttgaaaaac tacgacgggt acgatgtttc ccgtattgaa cgtcatgtcc
    12061 tgccaagatg attctccttt gtaaataagt tccaagcctt gtcaatcagg cttttctaat
    12121 cgccatatgg ttgtaaaccc cttatcaccg tgtcctcttg acgaattttc agaatcttta
    12181 agcctctgtt acaaatgctc aaaatcttga aaaaaagcac aaaaagagca gctaaatctg
    12241 actttttcag aagatttaac tgctgtgagc cttgtctgga caatatttca gacaaaacct
    12301 acgacaaatg attacccata ttatacccta tttagctaga tttttcaagg ggtttcagta
    12361 ggtttttggt aaattttttc ccatagaaaa cttggcatca cattcgaatc acgctatggt
    12421 acaaaaaact gaaaaaacta ttgactgaaa atcattttca aggtataata ataaacgtta
    12481 aggcggtata gccaagtggt aaggcacggc tctgcaaaag cttgatcgtc ggttcaaatc
    12541 cgtctaccgc cttctataac ttgatttatc aggtttcaaa tgaacagaaa gcccaatttg
    12601 aagggctttt tttattttcc ctcgaataaa tacgtataac tttaaaaact tttggagcga
    12661 gtttgtggca gagttctttc catggcataa ttcccttttg aaatcaattg aaaaaagctt
    12721 cgtcacgcct ggtgacaaaa gcctctagtt tattctgttt cttcttctat ttcgacttct
    12781 gtgatttgga cttttacctt ggtaacacgt ccattcttca ctttatcatt ggttaagata
    12841 aactgtttgt tttggctgac caattcatag ctgagtttct cagtcgttgg aatggttccc
    12901 actcctgtca aataataacc agcgatggta tcaacgtcat cactttccag ttcaacatca
    12961 aagtaattat tgaaatcatt gagggtcata gttccttgaa caatgtaggt atcctcgcca
    13021 atctgatgaa catctattgc tgctttgtcc gtttcatcat caatttcacc aacaatttcc
    13081 tctaagaggt cttccaaagt caccaaacca gccataccac cgtattcatc cagcaagatt
    13141 gccatttgtc tttgggtatt tcgcagttct tttagcaagt catccacaaa aatagtttca
    13201 ggtacaaaaa gtggatcttg taaaattctc ttccaaacaa tattgtcaaa accgtccaca
    13261 aagcctgcct taaggagact cttggtgtga atgattccaa ttacattgtc cttatcccca
    13321 tcataaaccg ggatacgaga ataattttgt tttaaaatac tttggataat ggcttgacta
    13381 tcatcctgaa tatccaccat aaaggcatcc gttcgaggaa ccataacctc tcgtgccatc
    13441 agttcatcga gcgaaaagac accttgtagc atctcaatct catcagcatc caatgtttct
    13501 tcactatttg tcagcatata ggcaatttca tcacgggtca tcttttcatc cgcatcatcg
    13561 aatgacatag gagtcaaatg gctcaagaaa ttggtcgaag cagctaaaag ccaaacaaaa
    13621 ggactgacta gttttccgat cccaatgata atcggcgctg tacgaattgc caaggcatcc
    13681 tttagattaa gagcgattct cttaggatat aattccccaa aaacgatgga aatataggtc
    13741 aaaaatgcca aggatagaaa agttgccacg gcttgtgctg tttcgccatt cccaagccaa
    13801 gaggcaatca cacgtcctag agtatcagtt aaactcgccc ctgataagat tgtaatcagg
    13861 gtgattccta cctgaatggt tgataaaaag tggttaggat tttctagtac cttcagcagg
    13921 cggatgtagc gtctgtctcc ttcttccgcc ttttgttcaa ctcgggcacg attaagagaa
    13981 accatggcca tttctgtggc tgagaaaaag gcatttaata ccgtcaagat aaacaataaa
    14041 acaaattgta gcaacaaatt ctgactactt gggtcttcca tagttcttct cctaaaatag
    14101 tatcttatcc tttattatat cacaaaattt aatccaatac atattatttt tttcttagcg
    14161 taacttccat ctctctccca aaactggaag ttagtctaag acggatttcc actgatttca
    14221 cgcgtttttc tcatactaaa agctaggttg tgggaaactg gaagttagtt ttagaagtta
    14281 ctattttttc ttagtacctg ttctagccct gcttaaacta gtaaaaagaa ctcctacatc
    14341 cataagtgac ataggagttt aggcttatct tttactgagt tacagttact tctccagttc
    14401 ggtaatccag ttgaagtccc ttttgaacat tgggaactag aacattgaat tccaattctc
    14461 catccgaaga cttggcttca atctgtgaag ctgagggaac taaatcctcg tttgaagcgt
    14521 agtaaagggt tacacggtaa cggacacgct tgttttggtc caaggcttta cgcaccttgc
    14581 tttcatagta gttttgacca gtcgaatact cggcttgtgc ctgatttgcc caggctgtct
    14641 gaacagcaat gtttttagga ttgcttgttg aggcatcaaa accatccaaa ccaccgatta
    14701 aggcatagcc taacaaatga cctctatcga ctgcatgggt ataagagccc tttagattct
    14761 tgacctgatg ccaacctgga ggagtccaag aagttgaacc attcccagtt tctttacgat
    14821 tcttgtactg acgagtggcc ttagacaaga gggcattagc tacggttgga acagtttcct
    14881 tgcccactgt ctttgtttta ttgtcagcgt agggcttact tgaaaccttg gcatctagat
    14941 ttgttttatt accattgacg ataaaagcac ctgagccatt ccactccaga ctccccttta
    15001 tttgactctt gactgcgtct gttaagacac tctctgccaa tgcttgacta ggagcttcag
    15061 gcccttgttt tttctgacta agattggttt tgggactatt aggtgccgac tgcatctgct
    15121 tgatataata gctccctgta gacaaaagca ataacactag cagtccgatt agtgtctgtc
    15181 ttgttttttt gttcatattt ctccttatct ttagaaaaag gctggttctc cagcctaatt
    15241 tcctgtaaat ttatgaatca attcctgcca ttttgctgga gacaggatag cccatggatc
    15301 ttgacccttg cccaagattc cataacctac cattagaccg attcctagag ccagagtacc
    15361 taaaatcagt actatgatga ctaaaagtaa acgattgatt acgtagcttg atttcttatt
    15421 catcttcatc gcttgcctca atccgctgaa tcttagcacc tagctgcgcc aacttctcat
    15481 ggaaaccgta gtaacctcta tccaagtgaa ccaatttacc gaccacagtt tctccctgtg
    15541 ctaccaaacc tgtcaaaatc aaggctgcac tggcacgaag gtcagttgaa agaacttctg
    15601 ctccctgcaa aggctgtcca ccaacaatac gagctgtatc acggataatc tcagaatgca
    15661 agcccatgcg gcgcatctct tctaggtgtt ggaaacgatt ttcgaaaact gtctccacca
    15721 tggttgattc gccttttgca actgtcatca aggctgtaaa ttgagcctgc atatctgttg
    15781 gaaatcctgg gtggggcaag gttttcacat gaacagcttt tagattttct agttgagaac
    15841 gaacacgaat tccttcgtct tcttcaatta cttcaacacc catttcaagt aacttggcaa
    15901 tcaagggacg gttgtgctcc cagacagcgt ctcgaatcaa gacatcacca ccagtcatgg
    15961 cagcagctac cataaaggtt cctgcttcga tacggtcttg gactacattg tgagtcgtac
    16021 catgaagttt ctcaacacca gtaatggtta tagtctctgt accagcacct ttgaccttgg
    16081 ctcccatttc attaaggaga atggctaagt caacaatctc aggctcacgc gcagcattct
    16141 caatcactgt caccccatca gccagagtcg ctgccatcat caagttctgc gttgcaccaa
    16201 cacttggaaa gtccatatag atatgagcgc catgcaagcg ttctgccttg gcttcgatgt
    16261 aaccagctgt ctgactaatc ttaaccccca tagcttccag acctttcaaa tgaagatcaa
    16321 taggacggct accaatcgta caaccacctg gcatggatac cttggcatga cccacacggg
    16381 caaggattgg ccctaataca acgatggagg cgcgcatctt gctgacatac ttgtaagggg
    16441 cttcctcagt gatgtcgcca gtagcatcca ccttgacaag atgagcttcc tcatcaaagt
    16501 caaccttggc attcaaacca ccaactacct gattcataat aaagacatcc gacaaaatcg
    16561 gaacattctg caagacggtc tttccttcac ttgctagaat agtcgctgcc aacaagggta
    16621 agactgcatt ttttgctccc tcgatcgtca cgcttcctac cagacgatta tcgccacctt
    16681 gaaccacaat tttatccata ctcgtttcct ttactcttga tttcataata atcctctaag
    16741 cgcttcttgc cacaaatgat acaggctaat aaagaaagaa ctcaggatgt agcctatgac
    16801 aatgctaaaa aaggctacta ataaacgaac ttttcttgta ttatcatctg tcacttttaa
    16861 aaccttctcc catctaacaa gatcctttaa aaggtaaaaa ctcacataaa taaagaacat
    16921 atgactactt agagtgaata ataattgaac catttgacta ttataccatc ttctctgttt
    16981 gtgcgctagt ttggaaactt cactcaaaaa ttagggattg tttttcaagt aatcaatcgc
    17041 atcttgtagg gttttaacgg gcacgatttt catatccgtc ttgattgttt tagccgcttc
    17101 tagggctgtt tggtagttgt ttttcgcgtc cggatgcgcc ttttgttctt cttcgctaac
    17161 agggttatca ggagcaaaga aaatagcagc acctgcccta gccgaagcta caaccttctt
    17221 atcaatacct ccaatgtctc ccacattacc atcgcggtca atggtacctg taccggcaac
    17281 aatacgacca ttacgaagat ctgggtgagc tatttgagta tagatagcta gactaaacat
    17341 gagaccagca cttggaccgc caataccagc tgttgaaaag ctaattggga cattgctgat
    17401 tacctctgta cggtcaatca agccgattcc aattccattt ttgccatttt ccaaggtgat
    17461 gatttttcct tctgcagact tggtttgccc atcctcttca taggtgacct tgacggaatc
    17521 ccctaatttt tgagaactga cgtaatcaat caagtctttg gaactatcaa aggtctgatc
    17581 attgactgct gtgactgtat cagagatatt gagaatccct ttaaaggttg aattatccgt
    17641 cacattcaaa acataaactc caaagtactt gagttcgata tccttaccag ctgtttttag
    17701 tccttgatac ttggccatat tttgtgatgt ttgcatgtag aattgattga ttcgcataaa
    17761 ttcaacatcg gaagaaccac ctgtagtctc ctgagcacta cgaatatctg taaaaggtgt
    17821 caaccaagca taaatcatat gagctaaagt ggcatgttga acaccaaccg taacgaattg
    17881 ataggcacca gcttccttat cttctgtgtc atttacttta aggacttggc gaatatcttc
    17941 cgaaccacct ggaacctcta tataataagg caagggcact acaaatgcca agaaggtcac
    18001 aatcaaggcc gcaatgacgt ataagggcca tctaatcttt tttttcattt cttatttcct
    18061 ccaaaatact ctcgggaaca tagcaggcaa tatcctgacc aaacttcaaa agctctctaa
    18121 cgcctgatga actgatatag agatgttcag gtcgactatg taaataaata gtctctatat
    18181 cagaagacag ctgatgattg tagtaatcaa aactggcttc atattgcaaa tccgacgcat
    18241 ttctcaagcc tcgcactagg caagtagccc ccagtctttt tgcgacatcg accaccaatt
    18301 tatcatgaga agacacgact ttaacatttc ccaaatgttt cacagccttt tctaaccccc
    18361 gtttacgatt ttcaagaggg agaaatcctt gtttgtgggg attaaaaaaa atacccacat
    18421 aaagcttatc aaagagtctg ctcgcccgtt caatcatatc cagatgccca tttgtcatcg
    18481 gatcaaatga gcctgtgaat aagccaatct tatctgacat agactgtcac cttactaatt
    18541 ccataaatct tttccttcca gatacccaga caggcaatct cttctggaag ttcaacggcc
    18601 ttatccgtct cgcacacaac cataacatct tcagaaaaaa gctctctctc agccattttt
    18661 tcaatatctg ctacgatttg ttccttggca tagggagggt ctaagaaaac gaggtcaaat
    18721 tccccagata cctgttccaa tgccctttct gcatccattt tgaggagttg aaattttcca
    18781 acttccttgg tcatctggat attttcagcc acgatggtct gagccttacg gtctcgctcc
    18841 accaaaacag cactggacat gccacgcgat actgcttcga tagataaacc accactacct
    18901 gcataaaggt ccaagactcg tcccacttca aagtagggac caatcatgtt aaaaatggct
    18961 cccctaacct tatccgaagt aggtcttgtt gtcttgcctt ctagtgtctt gaggggacgt
    19021 cccccataga ttcctgatac gattttcata ctgtttatta taccaaatta tagacaaaaa
    19081 gagaaagaaa accgaacctt gcggttcgat tctctacaaa atattttcgt aagtatcgcg
    19141 gacttcttga ggccaaacac ttgtttgcac ttctccgatg tgtctcttgc gaagtaggaa
    19201 catggccata cgagattgtc caattcctcc accgattgtc aatgggaata ggccattcaa
    19261 caaagacttg tgccattcca attctaagcg gtcttcatca cctgtaattt ccacctgacg
    19321 tctaagagtt tcttcatcta cacgaattcc catagaagac aactcaaagg ctccacctaa
    19381 agactcattc cagacaagaa tatcaccatt tagacccttg tagccattct cagactcgct
    19441 tgtccagtca tcatagtctg gtgcacgtcc atcgtgcggt ttaccatctg gcaactcgcc
    19501 accgatacca atcaaaaaga cggctccaaa ttctttacaa atcgcatttt cacgttcttt
    19561 aggtgtcaag tctgggtagc gttctaccaa ttcttctgta tggataaagg tgatttgttt
    19621 tggcaagata gactcgatgt catagcgggc ttcaacagct agctcagtca ggcgaatagc
    19681 cttataaatc ttctcaactg tttcttttag ataaacgatg ttacgcttac catttggaat
    19741 aaccttctcc cagtcccact ggtcaacata aacagagtgg gttgcatcca aggaatcctc
    19801 atctggacga agggctttca tgtggacaaa gagaccctct ccttcaccaa agccaaaacg
    19861 agccaaggtg tggcgtttcc atttagcaag tgagtgcacc acttcataag tagcatcagg
    19921 gatttggaga accttgaccg atactggatt ttccacacca gacaggttgt cctgcattcc
    19981 gtcaccgacc ttactcaaga taggaccttg aacttcgaca acttctagct tatctttcaa
    20041 atactgggta aaagtgtttt tgacaaagga aatttcttct tgttgatgga taaaactttt
    20101 cttcatagac aactcctcaa aaatttaata aacgtattat acacctattt ccaagaaaag
    20161 aaaagagaaa atttaaaaaa aatcagtgtc actcaaaaca ctgatttcat agacctttta
    20221 gtcattgcga ccaaagatac gtagaatact taggaaaaga ttgataaaat caagatagat
    20281 gctgagagcc attgacacca cccagcctgt cgctacacga ccttgtgatt gttcataggc
    20341 gaggcgaatc ttttggttat cccaagcaat caaccctgaa aaaaccaaaa ccatggctac
    20401 gctaatcata taatcaaaga agccactagc caagaaaata ttgactacca tagcaatcag
    20461 taaaccaatg agagctgcca tcattgctcg accaatccca ctcaagtctt tcttggtaaa
    20521 gataccaact gccgccatga caaagaagag aagggcgctc gatacaaagg cagataaaac
    20581 tgtacccgga gtatagaaag ccaccacaaa accaagggta aagccgttta aaacggagta
    20641 aagtaaaaat actggaagag cagctggact atttcttgaa gccatgctac tggcaacgaa
    20701 aaccaaagcc aactccgcaa aagtagcaat ggtcaaccag agacgcccct gcatcaaaaa
    20761 gtaaaccaac tgagactgaa agaccgtcaa cataaggcct gataccaaag cagatagtcc
    20821 gattcccaga ccaacaaagg cataaacctt agcgtaaaat tgattgagac ctgcacggtc
    20881 atgtataata gtgtgattca tccatttctc cttttctgtg aacatctttc cttgattata
    20941 acaaaaaaag ttaaaattag cttaaatgga agattaaaat accggctgca accgcaacat
    21001 tcaaactctc ggcctgcccc ttcatgctaa tatggaccaa ctggtctgca ctttcagcca
    21061 taaggggact aattccttga ccctcatttc ccataactag tacaaaattt tctatagaag
    21121 gcagttctct gtaatcaaca gaatctttag atagggttgt tgctagcact gggatagcta
    21181 cctttttagt ttcgtcaaga agcgcttgac tagtcatccg gtaaatgggc agatggaaat
    21241 gactaccttg catggaacgt agggttttga gactgtagat gtctgccgac ttatctgaaa
    21301 caatcactcc tgtaaaacct gctgcatccg cagttcgaat gatagttcct acattaccag
    21361 gatcttgcac atcttccaaa aacaagaact tgccctgact caaatcagct tgtcctactt
    21421 cttctttttg aaccacggca acaattccct gtggagtctg agaatccgcc aaatctagca
    21481 aaatatcctc tgaaatccag acagtttgcg gaaaagcagc taactgattt cgataatttt
    21541 ctagggcaaa gattttctca atcgtcactc cagcttggac agcttcttca aacaagtgcc
    21601 agccttcaat caaataggca gacttgcggt attttttttg gtgtaatttc ttagcatttt
    21661 ttaccacaga attggctttt gaggttataa tagtcataga aatattataa cacaatcaaa
    21721 ggggtttggt atgcaaaagg ttagaatgat tgcccaaggt agggtgcagg gagtcggctt
    21781 tcgttggggt gtttatagcc tggcccttga aatcggtggc atcacaggtc gggtatggaa
    21841 taacgacgat ggcacagtgg aaatcttagc ccaagcagac tcatctgcta tcatggcaaa
    21901 atttatccaa gaaatccgaa aaggaccgac acctttttca aaagtaagct acttagatgt
    21961 caaactaagc aactttcctc cctactctga ctttaaaatc gcaaattagg tctccagaac
    22021 tattgtatat tttgtaaaaa aacagtagaa tagaaaggta taatttttaa agaaggaata
    22081 aaaacagtga aatctattaa acgttttgca ttctcggcta tgggagtggc tatgttgctt
    22141 gtcttgactg gctgtgtcaa tgtcgataaa accacaggtc agccaacagg atttatttgg
    22201 aatacgatcg gagcgcctat ggctgaagcc atcaagtact tcgctactga taaaggtcta
    22261 ggctttggtg tcgctatcat tatcgtaacc attatcgtac gcttgattat cttaccactt
    22321 ggtatctacc aatcatggaa ggcaacgctt cactctgaaa agatgaacgc tctcaagcat
    22381 gtccttgagc cacaccaaac acgtctcaaa gaagcaacta ctcaagaaga aaaactcgaa
    22441 gcccaacaag ccctctttgc cgctcaaaaa gagcacggca tcagcatgtt tggtggtgta
    22501 ggatgtttcc ctatcctcct tcaaatgcct ttcttctctg ctatctactt tgctgcccaa
    22561 catactgaag gggttgctca agcaagctac ctaggcattc ctctaggttc tccaagtatg
    22621 attttggttg cctgtgctgg tgtcctttac tatcttcaat cgctcctttc acttcacgga
    22681 gtagaagatg aaatgcaaag agaacaaatc aagaaaatga tttacatgag cccactcatg
    22741 atcgtcgtct tctccctctt ctcaccagct agtgtcacac tttactgggt tgtcggtggt
    22801 ttcatgatga ttctccaaca gtttatcgtc aactatatcg ttcgtccaaa acttcgcaaa
    22861 aaagtccgtg aagaactagc caagaaccca ccaaaagcaa gtgctttctc taaaccaagt
    22921 ggacgaaaag acgttacccc tgaacaacca actgctatca caagcaagaa aaaacacaaa
    22981 aatcgcaacg ctggaaaaca acgttcgaga taagaagaaa aaggcttagc tgatttgcta
    23041 agtctttttg caaatcaaaa gcccgatgtt tccatcaggc ttcttttcta tccatgtaca
    23101 cgtttcatat aatcttgata actttcggta tccatgagtt ttttagcgtt cttgacgcga
    23161 tctgctgttg gtggtttgac tccttcgagg gaatatggaa ttccaagttc acgccacttg
    23221 aactcaccca tggtgtgata aggtagaatt tcaaacttat caacattttt gagggtcttg
    23281 acgaacttac caagttcaat caagtcatca tctctgtctg tcaatcctgg aactagcacg
    23341 tggcgaatcc agacaggttt tccaatatct gatagatact gggcacaagc caagatattt
    23401 ttattagttt ggctagtgac aatcttgtgc tgttcttcgt tgatttcctt gatatccaaa
    23461 agaaccaagt cagtgacagc catgagtttg tcaaacttct caaggtaacg tggtttatta
    23521 cggaaaggaa gagcacaggt atccaaggta cagtggattc cttgttcctt agccttggtg
    23581 aagagagcaa tcaggaaatc aatctgcaag agagcttctc ctccactgac tgtaatccca
    23641 cccttatttc cccagaaacc acggtagcgc aaggcctctg tcaagacatc atctaccgtc
    23701 cgttcacgtg acttattgga ctccatagcc caagtgtctg ggttgtggca atactggcaa
    23761 cgcatgtgac agccctgcaa aaagacaata aagcgaatac caggcccatc tactgaccca
    23821 aagctttctg tcgaatgcac cattcctgtc acttgtccat aatcaattgt ttcttcagac
    23881 atatcgttac cttccttgaa aacgttttat agttttatta tatcacgact tgaaggaaaa
    23941 acaagatttt tgcctatttt ttagaaagca atctgttttt caatttcatt ttcaatctat
    24001 tatcagatta ttcttcaaaa tcgaagccat ataaggttgc aaaatagtcc tcagggcgct
    24061 ctgcacggcg gatttgacgg gctttacctt cttcggtata gaggatttcc gcagaacgta
    24121 atttggcatt atactggtag cccattgaaa atccgtgggc acctgtatca tgaattacca
    24181 gcaaatcacc gatttctgta tgaggcagtt cgcgattgac tgcaaattta tcattgtttt
    24241 cacagagtga accaaccaca tctaccgctt cagctggtcc atctggatgg gtcacgttgc
    24301 taatatgatg gtaagctccg tacatagctg gacgtatgag gttgactgct gaggcatcca
    24361 cacctagata ggtacggtag gtttccttct tatgagtcac tcttgtgact agagcaccgt
    24421 gaggtgccag cataaaacga cccaattcgg tgaaaatctt gacctgacca agacctgctg
    24481 acgtaagaac ttcttcatac accttacgaa ctccctcacc aatcaaggcg atatcgttcg
    24541 gctcctggtc tggacgataa ttaacaccaa taccgccaga aagattgata aagtctagcg
    24601 aaatgcccaa cttttccttg atttcaacag ccagttcaaa gagctgacga gccaactctg
    24661 gataatagag atgggtcacg gtattggacg ctaggaagga gtgaatccca aaagtcttgg
    24721 ctcctttttc cttcaagata gcaaaggctt caaagagctg gtccttggtc atgccaaact
    24781 tagcctcccc aggattgtcc ataatgtctg tccccagttc aaaaacgcct ccaggattat
    24841 aacgacaaga gatgatttct ggaatgcctg ctactctctc cagatgttca atatcttcaa
    24901 aggcatccaa gttaatggtc gcacccaatt cacgtgcata ggcgtattcc ttgtctggcg
    24961 tgttgttgga agagaacata atctcagaac ccagaaagtc cagtttatgg ctcatcaaaa
    25021 gctctacata actagagcag tccacaccac aaccttcttc ttggagaatt ttcaaaatag
    25081 ctggagttgg agtagcctta actgcaaaat attccttaaa gcccttgttc cacgaaaaag
    25141 cttggttgac ggctcttgcc ttctcacgaa tccccttctc atcatacaag tgaaagggag
    25201 tcgggaactc ggcaacaatc gcttctaact cttctctatt gataaatggt gttttcataa
    25261 gcttccttct attctgtttg caaagaaagg ctgggacaat cgttccaacc tttagttcta
    25321 tctcttattt atcttcgtca aagatattgc caacctcaac atcgatggct tggttcttga
    25381 catcaatatt ggttaccttc aagagtgact tgtagtcaaa ctgcttttca cgttcttctt
    25441 gggcattgtc cgcaaagacc gctacacctg ccagttctga gtcgaactcg cgcaagagac
    25501 taatcatacc attgaccgtt ccgccacctt tcaagaagtc atccacaatc aagacacggc
    25561 tgcctgcctt aagactacgt tttgaaagga acattttctc gatacggtca ccacttgaac
    25621 ctgaaacata gttgacgcta acagttgaac cttcggtaat tttcaggtca cggcgcacaa
    25681 tgacaaaaga gacattgagg acattggcaa ctgcatttgc aagtggcaca cccttagttg
    25741 ctacggtcat aaccgcgtca attttttggt ccataaagct tttggcaata atacgaccaa
    25801 tatttttcaa gatggctggt gtgctaagca aatcagacag atagatataa ccacctggca
    25861 agatacggtc actttctgac aacttggtac gcaagtcttc aaccatttcc ttagcatcct
    25921 gactcgaaat agacggtgtg aagatgacac ctccgccagc cccagtcact gtctggatat
    25981 gaccgatttc aatttcctca aaggcgcgtt tgataatgac gatatcttct gagatggatg
    26041 atttagcaga ctcatacttt tcagcaaaag tattgagact agttagttta taaggattat
    26101 taatcaaata gttggaaatg acaaccatcc gatcacttct tcttaatttc atttctattt
    26161 cctattccat ttttattcaa aaaatcaaaa agcaaactag aaagctggtc gctggtggtt
    26221 caaaacactg ttttgagatt gtcaatagaa ctgacaaacc ctgtaatata cctgcatata
    26281 tacatacgac aaggcgatac taccctagtt tgaagagatt ttcgaagagt attcattttt
    26341 gtcttttact tattatacca tattcacata aaaaaacgaa cattcttatc ctaaaaaatg
    26401 ctcatttttc ttaaattatc aatctaaatc tggtttatag aaggaacgat tatccatagc
    26461 gaagatttta ttggtcatct ctcctttatc caccaaagcc agagctgttg acatcatcat
    26521 catgcttgca tccagattgt caatcatatg gataatctct gcctccataa tacgtggacg
    26581 gactggactt ccatattcaa gcaagccgtg gtgactgagg atgacatgac gaagcaaaac
    26641 gacttcttcc ttggtatcat cgatgccgag ttccataact gtcttggtaa tttcgctatc
    26701 aatgagagcg atatgtccaa gaagattacc tcgcactgtg tactctgtct ggtctggccc
    26761 cgtcaactcg ataaccttag ctaagtcatg cagcataatc cccgcataga gcaggctctt
    26821 attgagctga ggataaactt cgctaatagc gtctgccaaa cgtaccatgg tcgccgtatg
    26881 ataagccaac cccgtttcaa aggcatggtg gttggtcttg gcggctggat aggagtagaa
    26941 ttccttatca tacttggtgt agagatttcg gacaatccgt tgccagacag gattttcaat
    27001 tttgaaaatc atttgcgaca tgtagtcacg aatttccttg acatcaactg gtgacttgac
    27061 cttgaaatca gctgggtcat tgggttcacc agcttgaggc aggcggagag taatttgatt
    27121 gacttgaggg gtattgttat aaacttctcg gcgtcctttc atgtggacaa ccttacctgc
    27181 ggtaaaggcc tcaatgttat gaggttgggc atcccagagc ttcccatcaa tctcgccact
    27241 atcatcttgg aaggtaaagg ctaggtagtt tttcccagct cgagtttgcc tcaggtcagc
    27301 tgatttgatt aggtaaaagc cttcaaataa ctcatctttt ttcatgtgac taatcttcat
    27361 attcttcctc attttcttga aaatggagta gatcaagcgc aggctcacct tctgacaact
    27421 caatgtgacg gagcgtccgc tcgatagcta tggtacgacg gtttaataat tcatcaatat
    27481 tgccagaggc atgttggaga tgtttttgtg ccttgaccag aataccacca aacttgccaa
    27541 actcggtctt gacactggca agagtcttgc tgatatggtc ggcactcttt tggatattaa
    27601 gggtcttgaa accaactgat agggagttaa gaagggctga tagggtactt ggtcctgcaa
    27661 caataatctg ttcttcccgt ctcaaatcat caaagaagac cggattgcgg acgatttctg
    27721 agtagagacc ttctgtcgga acaaacaaaa ctccaaaatt ggtcgtccga ggtggtgcta
    27781 tgtacttgtt cctaatatcc ctagcaaagc gcttgacgct tgctaggagt gacttacgac
    27841 agcgttcaat ctcatccttg tcacctgtct cataggcttc ttccaagcgg taataatctg
    27901 ccagtggaaa cttagagtca attggcagat aaacgtattc ttggtcgcct tgtccgggta
    27961 acttgatggc atactccact cgttcactag agttttcaac cgttgcgtat tctcgttcgt
    28021 actgggcagg tgtcatgatg tcttcaataa tttgccccag ttgcaattct cccagaatcc
    28081 ctcgcgtctt ggttccagag agaaccttgt taagagctcc gacatcacgg gcaactgtct
    28141 gcatttctcc aaggccacga ttgacagact ccagttgttt agaaactgtc tcaaaggaag
    28201 cctgtaagcg tgtctgcaag gtcttttcta gtttttcctc gaccgtctgg cgcatttgtt
    28261 ccaaacgttg ctcatttgat tcctgcaagg cttggagacg ttggtctgtc ttgtctctag
    28321 tttggaggag attatctgtc atttcttgac ggacttgggt cagaccttgg tgcaattcaa
    28381 tccgcacttc ttgcaaacgg tcgctgacaa ccacttccaa atctttttgg tctaactggc
    28441 tggcttgtct ggcttggtca aagcggtaat ccaactggtc tgacaaatga tctgcctgat
    28501 cctccaagct cttacttaag tgtttctcct gcctatcctg tctttgccaa atcagaaaga
    28561 gaccagctag gttggcaatt aataatagaa taagtaaact ttccatccta cctcctgtcc
    28621 ttgctatgca gtacgaccac ataaccatct gggcaagtca ccgacacttc cctatctata
    28681 tattcgttag aagcgtacac ttttttaaag aaaaaattct cctctgtcaa ctcatactta
    28741 gctccaagaa tagtcagctg gctatcccga actggcataa aggctagata gtcgtagtct
    28801 gaacgaggtt ctagctgact ggtcccttct gaacaatagg caatcaaatt ttgcccatcc
    28861 tcaatttcta tttgacgcat atagggtgcc aacttaggat tgctaggtag aaagacattg
    28921 gccaacatat ggtcaatacg gccacccaag gcaccgaaaa tagtgacctc agcctgagga
    28981 ttttgttcaa agatggttaa gagagccaat tccaaatcag tatcatcttt ttctggccgg
    29041 gcttggacaa aatactgggc acgtttttga atcacctgtc gctcttcttc cgtcacagaa
    29101 tcaaaatctc cgactgctag agcaagaggt aagtcttctt ccaagaccca gagcgagcct
    29161 cgatccaccc caacaaaagc atcaaaatct gtccgataat gaccgcggtt tccgcctgca
    29221 aaaactgcaa ccctagtcca gttgttttct gagagtttgt actcgctcat tgacttctcc
    29281 cttaaagaca taggaacctg ctacaaaaac agtcgcacca gcttctttgg cttgagcaat
    29341 agtttggtca tcaatcccac catccacttc gatttcaaag ttcaaacctt tttcctcacg
    29401 aagagcaacc aactcacgaa ccttatccat ggtttctggc agaaaggctt gcccaccaaa
    29461 acctggatta accgtcatga ctaaaacttg gtcaactaga tgaaggacgt gcttgatggc
    29521 ttcaactggt gtgccaggat tgataacgac tgaaggctta actccgagtg aacgaatttt
    29581 ttggagggcg ccatgaatat gaggtgttgc ttctacatgg atactgatga tgtctgcacc
    29641 tgcacgcgca aaatcttcca gatgatgctc agggtttgac accatcaagt ggcaatcgaa
    29701 aaccatctta ctatgaggac gaaggctctc gaccacacct gcaccaaaac tgatttgcgg
    29761 tacaaaatga ctgtccatga tatcgatatg ggcatattct gccccagttg cttctagacg
    29821 tttgatttca cgttcaaagt tggcataatc tgctgccaga attgacggag caatcttgta
    29881 ttgagacata ggtttctcct tattttggaa tttttttgct gactttttta taggtttctc
    29941 tacgattttc aatttcacta aggaattgca ggtaattatc aaaacggaag gttgcaataa
    30001 caccctcttc aacagctggt ttgacggcac aagacggctc atgggtatgg gtacaagtac
    30061 ggaacttaca atctcggcta acagtagcaa tctctgggaa agcctgattg aggtcttcag
    30121 cccttgatac ttcatagtcc agagatgaaa agcctggtgt atctgcgatt ttacccccgt
    30181 tgagattgta aaaactaaca gctcgagtgg tatggcgacc gcgacctaga ctgtctgaaa
    30241 tttctcccgt ttcaagattg aggtctggta cgagtttatt gagaagagtt gacttcccaa
    30301 cacctgtctg ccccataaag accgtaacct tgcctgttaa caaagacagg agttcctctt
    30361 tactggtcac aaagtcatag ccgatgtcac cataggtctg ccggtaaaaa tccagttctc
    30421 ccctatcttc caacaaatcc attttggaaa tatagacaat gggatggatg cccttgtgct
    30481 ccaaaagaac caagaaacga tccagcaaat tgctgttaaa atcaggttcc ttgacggaca
    30541 tgattactac agcttgatcg atattgacaa taggcggacg aactagactg tttttccgtt
    30601 cgtgaatttt taggatatag ccttctgaat tttcctcggc agagaaatct acccagtccc
    30661 caacataagg ggtatggcct tttttacgga aattcccacg cgcgcgtgtt tgataaacct
    30721 ggccatcact ctccacatag tagaaacctg ccaaggcttt aatgatttgt ccctgcatct
    30781 tagagtcctt gccctttaag tgcgtctgct agaccggcaa attctgccaa gctgagagct
    30841 tccccacgca cacttggtga caagcctgcc tggtccaaag ccttggtcag cttgtccttg
    30901 acctcttcag tcttaccaaa gtaacctgtc aagttattcc acaaggtctt acggcgatgg
    30961 ataaaactag ccttggaaac cttaaagaag aagttctcat cttccactgc tacagctggc
    31021 tctggacggc gcaccatttt caagatggct gaatccacat ttggcgctgg cacaaagacc
    31081 gtacgaggca cgataaaggc aaccttggct gtcatgtaat actgcacggc gatagacaag
    31141 ctaccgtaag ccttggtgtt aggctgggct gaaatgcggt ccgctacttc tttctgcatc
    31201 atgaccacaa actcactaaa aggaatgcca ctctcaatca agtgcatgag aataggcgtc
    31261 gtgatgtagt aaggcaaatt agccactacc ttgattggca ggttaggatt tttaaaattt
    31321 tggatatgtt gcgccaaatc aaccttgaga atatcttcgt taactacagt cacattatca
    31381 aaatcacgca gggtatctgc caaaattggc accaaacggt ggtcaatctc aaaagccatg
    31441 acttgggctg cacgctcagc cagaaactcc gtcaaggcac caatacctgg cccgatttcg
    31501 atgacattga cctggtcatc aatttcagcc gtatccacaa ttttttgaag gatattggta
    31561 tccgtcagga aattttgccc gaaggacttt ttaaaggtaa aaccgtgacg ctccagcact
    31621 gccttggtca cgctataatc tgcaattctc atctattctc ttttctatta tctgttacta
    31681 ctattgtaac acattcccct tgtattttgg gaatgaaaat cataccaaaa aactatcttt
    31741 cctcatgaag aaagatagtc ttggaaatct ttaaaagtgg ccttaacagt tctctcgaaa
    31801 catgcgttca aaaaaatcag cttcttgata acttcgattt tcgggtaggg tcaaatccac
    31861 atcctcctcc acatcatcca ctgtcagttc aaccgtctga ggtaaatttt tcaaacgata
    31921 atgcttttgc ctttgccctt caatactagc aaaatcaagc aaatagccat gcactcggat
    31981 ttgaaccaaa aggagatgat tggtcatatt ttccatgatg aggatatctt ctaaaccacc
    32041 tctggcacta ggataatcag ataccctgcg aatacggatt ttttcacaca tgagcaagtt
    32101 tcctcatatc aatgatttca tcagccttat tccagactag gggattatgg gtcgcaatga
    32161 tgataattcg attttcatct ttcaaatcca ccaagagatt cataacctcc tctgaatttt
    32221 caggatcaag agctgctgtt ggttcatctg ccaaaatcaa gggtggattt ttcaaaatag
    32281 tcttagcaag ggaaactcgt tgggcctctc ccccagataa agtataaatt ttttgttcta
    32341 aatccaaata ccctagatta actttttcta aagcccccac ttgcctttcc aaacgttcta
    32401 cttttgagat tttctgacca acaaaaccca aatccaaatt ttctttgatt gattggtttt
    32461 ctaagaggcc aaaattttga aagagatagc ccatctgatc tcgaaaatac tcacgagtgg
    32521 gaatggtttt taaatctttc ccctgataga gaacccttcc tccatctatc ttttctagct
    32581 ttcccaagat attcagcagc gtcgtctttc cgcttccact ctttccgatt aaggcataaa
    32641 ccttgccctt ctccagcttg agattcaaac cagagaaaat cgcgcggtca ttaaatttct
    32701 tttccaatcc ttgaatatca atcatcttat tttcctttca atactgccat gctaccagct
    32761 tcttcttttt tgtcctgcct tactaaaatc aagagggcgt taagcgtaaa caaagctaca
    32821 actagagcgc taatcaaacc atctcttgtc aaaatactag ataggactag gccaagcaag
    32881 agaactcctc cttgcgccag taaatacttg ccatgaagct catagattgt cataccagca
    32941 agacgtttaa tcataagctc ccgtctgaac tgctcaaaat agagaagatt catggaatca
    33001 aataacaaga tagccgtaga cagggtcaaa atcgtcccaa taaggagaga gtaaaactcc
    33061 acccgtttgt catttagtac cttggcaaaa aatagctggc tttttaccaa gtaagaaacc
    33121 ttgtgataca gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc
    33181 aaggcactat tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct
    33241 tgcggcgtta gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca
    33301 tcattataga ggaaacgttc ctgtcctgtt tctgtaaaag ctagccttac ctgtgggagg
    33361 tagtatttct gactcgtcac ttctacactt tcagatgaaa agttttgcag gtaatctgta
    33421 aacaatcctt ggtagtaggt agactgctct cgcaagctct caggcaagat cagcccaaac
    33481 tctccctcag acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct
    33541 tctatcagat agcgtggtga gacatagata acattccctg acggtgtgta gtcactgaga
    33601 cgattgccat ctaggtccac ttctgctcca tctgagaaat tgtcaacatt gctcataata
    33661 taaaaagagt ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc
    33721 ttacgcgttc cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg
    33781 tctgaggact ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg
    33841 ggtaggagag ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc
    33901 atcaatgtca tcatacgttt gagagggagt ttccctttca atagatccac cagactattt
    33961 tcctgtaaac caagtagata gacgacactt agtaaggtag aaatccctgc cagggtcaat
    34021 ccataaagta gaagagcaat gatgaccagt tgcaccgttg ccataaacaa ggcaccttga
    34081 taccagagaa tccccaatcc caaaagactg gataccagca ctgagcagat aagctgtctc
    34141 acatcttcta acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga
    34201 atccctgcct gacgaaggga tttgatccga taaatcaggg tcagactcat aaaggtcagc
    34261 agaaaaatag ctaaactcag tagcaccata ggggtggccg tcaatagtaa gactatcgaa
    34321 aatggatctt ctccattcga aacaaagcct tgatagccaa gttctttcaa ggtggtctgt
    34381 aagctcactc catccaaact tcctgacaca atcaagtaag accctaataa atcactcgtt
    34441 tctgcactct ccttggagga aatggtcaga ccttctggaa gctctccctc accataagtg
    34501 gcataggtaa agagtgtttc tccagcttca tttggctcaa cgattcgacg ggcgatgaga
    34561 ctattatgct ctaccgccaa gtgactcaaa gcctctgtca cctcttcgcg actagctact
    34621 ggttgattta tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct
    34681 tctcgatggt caacggaagt tatcaccata taaagcgata ccaataccat tgaaatcaaa
    34741 ataaataaac gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga
    34801 ccacagtcac tgcgatgtta agaagcttat taagttcttt ctgctagcaa catcttcaaa
    34861 tatattatat ccgttttttc aagaactatc aaggacatca atgtccttaa aatctaacta
    34921 tttcatatta tttttagctt atatctaaaa aaacagttct aaagacgaac tttagaactg
    34981 ttttgatacg aggacaagga catttttgtc actgattcac tatgtttata aatatttttt
    35041 gacatcctct tgccattcct ctgtcaattt ctttactaga aatccatctc caattagctt
    35101 cgcaaatgtt ttagaagact gataaaatga ttcagctaaa ctaaaatctc tttctactct
    35161 taatgcttgc ttccacaaaa acataaatac aagaggtttc ttttgataac cttgagtttt
    35221 atccataatt tcttgtaaac acgatagata atcattaaaa caatcagtta ctcctacctt
    35281 ttcaagacaa cacattcctg aaataagagt atctctaatt ataaagtaat tctctatttg
    35341 agttaccttc ttctgttcca aaagaaagag cattagcttt tcgatttgat ttataaattt
    35401 ggcaagatct tttctaatga gcatttgata aaaaaacaaa cgaatcaaca acatatcatt
    35461 tgttgaataa acttcttttt ctatgatctg aggcatatgt tcctcaagta ttaactctgc
    35521 atattcaggc cttctagttc tagaagtatc caaacacgcc tgcaatactt cacatgctaa
    35581 ttgttcttct ttaggaagat tatcaaagta tgttttataa atctcttcca aacacgcttc
    35641 tttcttatca tactcctctt ctttaccata gattggttca cgtaaaatct ggtatttcaa
    35701 ttctaaataa gcaggaggaa gagctgaaaa atccggcata aggctataaa ctggaactcc
    35761 tagccggtga gcaatatagt ctaacttggg caaactcggt tgcgaagctc cactttcaat
    35821 tcgcgacagt tgacgaactg tcagttcttg ctcatctcca caaaaatctg gacgactaat
    35881 tcctttttct atccgaatct ctttaatttt ttgaccaatt aacatcagac gcctcctctt
    35941 ctacctgctt cgaaaaatac tgtgaaactt aaaaaattgt aacggtcaca tctttcctac
    36001 tcataagatt tcatagcttc ttccacttct gccaaagtaa ccccaaacaa ctctaggcgt
    36061 ttgaggagtt gcttgccgtt agaatagccg attcggagag tctctccgag atattcccta
    36121 cgcttacggc tgtctgcccc tactagaaaa ccaaggcgaa tcaagtcgct acgactaatg
    36181 tcaaactgac tctcatgttc aaattgttct gtcacctgag ctagagccgt tttcaggtct
    36241 tcatagctgg catgctcaat tcccagagaa cgccccttgg tcttggactt gggaacagct
    36301 tcatctcgct tgagaaaggc atgctgaact gttggaatgg ccgtcataat catgcgccga
    36361 atccgctccc cattaaaatc tgggtctgta aagacaatga ctccatgacg ttggtgtaga
    36421 cgctgaatcc gctctatgtc ctggtcattg atggcagaac ctcgagtctc ataggtctcc
    36481 acatcgaaat aacgcttgag attgaccgta tcatcgcgac cttcaaccac gataacttgg
    36541 gaaattttct ctttcattac ttgctgtcca atccaaaaat gcgttctgca tttgcagtcg
    36601 ttgccgccgc tagctcttct gtcgtcatac cacgcaagtc agcgataaag tccaccacat
    36661 agcgagtata ggctgtttta ttttcacggc cacgcttggg tacaggtgct aagtaaggcg
    36721 catctgtttc caccaacatc ttgtccaaag gtaactcttt agctgcttct tggaggtcag
    36781 ttgccttctt gaaagtcacc actcctgaga aggaaatggt cataccaaga tccacaaact
    36841 tctctgccca ctcaagcgtc cctgaaaatg aatgcatgat accaccacga ggaccaacgc
    36901 cctcactctt gataatctca taggtatctt ccagcgcatc acgggtatgg acaacaaaag
    36961 gcaaatccaa gttcttagat agctgaatct gacggcgaaa aacctgctcc tgcacctctt
    37021 tgggcgctgt catccaatgg tagtctaagc caatttcacc taaagccaca accttggaat
    37081 gttttaactt atccaacaag taagcctcaa cttcctctgt ataagtacca gcttctgtag
    37141 gatgccaacc aatagtcgca tagagctgct catactcatc taccaactcc aaggcatgct
    37201 caatcgtcgg tttatcaaaa ccaacaatat tcatctgtgt cacacccatc tcatcagcca
    37261 aggcaatttc ttctgcctca cgacctgcaa attcttctac attcaagtgt gtatgtgtat
    37321 caaaaatcat ctcttctaac ctcgttttct atcttctatt ataccaaaaa agaggagggg
    37381 cacctaattt ttcggtttcc cctcctctct tcaataggga gctattctgc tatcttttct
    37441 atccgatatt gcccatctcc tattccacag ttagagacag aagagattgg ctacattgat
    37501 agaatattcc tattcagcta aagtatgtga ttatcttggg ttctcacttt tctcacccat
    37561 cactaggatt gatgacttct caaaatccct cttataatct aactttaagt agagaataga
    37621 attttctagc tgttctattt tctacgtcta gtctttcttc ctagcaaagc aaaaccactt
    37681 gttgccacca ctagaccaag actagcaagt gctgcacttg atgctgaacc cgtgttaggt
    37741 aattgtttgc cagcaggtga ctggtaggta acatcttgca ttgttcctgc agttgcttgc
    37801 ggtgcacttg ttgtcttagg agcagtatta ggagccactg gtctcttagg aactgtaacc
    37861 atgacaatgg cttgcactcc aatcgtttct gcttccttca catcttccat agttttcgca
    37921 ttttcaatct ctttgagagc tgcttgtttt tctgcttcca ctcttgctaa aagttctgct
    37981 ttttctttat cagaaagcgg tgcgcctttg atttcatcct gcttgtcctt ggctgctttt
    38041 tcaatggcat ttttagctga ttctttttca gtagctaatt gcttagaagc ttgtgattga
    38101 gctgagtttt gtgaacctgt gtgagctgat ccacccgcct ggctaccacc gccttcattc
    38161 gcattagcat ctgagcttcc agtattgcct cccttatctc cacctggtgt agtttctagc
    38221 ttatactctg gtgtagcttc ttgagttaca gattcacctt tcgcagattg ttgaactgta
    38281 tcttttccta gaatcgtcac tactgaacca tctgggaatg tgattgttgc tgtaccatat
    38341 ccagctacat tgattgtcgc tccgtctaat gctgaaccat ttgcttgtaa aatagcaacc
    38401 ttaacttttt ctttttcttc atctgttaaa tgagttatat cttttacatc tactctttga
    38461 gcaggtgctt taacagttga tttttcagca gtcggtttag tgctatcttg tgcttttgga
    38521 tcttgtgcta ccaattgatt tcctggaatt gtaatagctg aaccatcttt aaagacgatt
    38581 gttgctgtac catatccacc tacttcaact ttatagtaaa ataaaataat aacaggacaa
    38641 atcgatcagg acagtcaaat cgatttctaa caatgtttta gaaacagagg tgtactattc
    38701 tagtttcaat ctactgtaac atcgcttccg aatccatttg catctactga acttttttac
    38761 aaaaataaaa atcagtagac tcgagttcct actgattttt gatagaattc gtttggatta
    38821 tgcagccaaa actttgcgtc ctttacgacg acgagctgcc aatacgcgac gaccattttt
    38881 agttgacata cggttacgga atccgtgttt gcgcgcacga cgaagtttac ttggttgata
    38941 agtacgtttc acgatgaata cctcctcata gattttgtat tcgtttagcc ggctataaag
    39001 tgatcagtta ctaaacatac tttactattc tatctgattc tttcactttt gtcaatagct
    39061 ctaggcaaat gtttccagct ttttcgaatg caagccctat tgaaagttct ataatgaagt
    39121 tagccacctt accttagtca agaattagat gtttcactat gtttgagtaa gttgatgatt
    39181 tcatttgata acaggtttga aactgttagg ctaggtggtc aaggctaatc atagccttgg
    39241 tttagctgaa aaaacaggtt caagggttcc tgttgtcaaa tgaaatgtga tttaaggtat
    39301 aagaaaacac ctctgtgcta tacttgttgt tcaccacaaa cacaaggaaa ggcacagaga
    39361 tgcaagaaca ttatacccca aaagggaaac atttgacaat agataaccgt cgcttgattg
    39421 agcggtggaa gaatgaaaat aagtccaatc gtgaaattgc aggcttgtta ggaaaggcgc
    39481 ctcaaacgat tcataatgaa gtcaaaagag gtacaacttt acaacaagtg agaaaagggc
    39541 tatacaaaaa ggtctattct gccgattacg cacaaactgt ttaccaattc aatcgaaaac
    39601 ggtcggtgaa aaagttaatt ttaacaaagg aaatcagaga gaagatctta cactatcata
    39661 agcaaaaatt ttcgcctgaa atgatggtta acaagaagca agtgaaagtt ggtatttcaa
    39721 ccatctacta ctggtttcat aatggtcatt taggattgac gaaggccgac atgctttatc
    39781 ccagaaaaag gaaaggtgtc aagaagcaag ctagtccgaa ctttaagccg gcaggtaaat
    39841 ctatcgaaga acgtcctgac gttattaatc ttcgcttgga aaatggtcat tatgaaattg
    39901 ataccgtcct actgactaag ataaaaaatt attgcctgtt agtcttaacc gaccggcgga
    39961 gcagacacca aattataagg ttaattccaa ataaaactgc tgaatctgtc aatcaggcgc
    40021 ttacgttact attaggggag catcgtattc tgtccattac tgcagataat ggttcggagt
    40081 tcaaacgatt gtctgaggta tttcctgagg aacatatcta ctacgcacat gcttactctt
    40141 catgggagag aggttcaaat gaaaatcata atcgattaat tcggagatgg ttacctaaag
    40201 gaaccaagaa aacgactccg aaagaagtag cttttatcga aaattggatt aacaactacc
    40261 ctaaaaaatg cttggactac aagtcgccaa gtgaatttct tttgggtggc taacttcaac
    40321 ttgaaatttg ggatgcaagc cctatctacg atactgtttc aagaaacgag tcatcttttc
    40381 ttggatttgg gctaactcat caacacgagg aaggtaaacg atacggaagt ggtctggttc
    40441 ctgccagtta aagcctcgac catgaaccaa gagaaccttt tcctgcttca agaaatcaag
    40501 gacaaactgc tcatcatcat cgatacggta catattgcgg tcgatttttg ggaagatata
    40561 gagccccgcc ttgggtttaa cggcagacaa acctggaata tcttgaatgg cattatagat
    40621 gaaatttctt tgctcgtaga ttcgtccacc aggaagaagc aattcatcga ctgattggtg
    40681 accccccaag gaagtttgta cgacttgttg ggccaaaacg ttagagcaaa ggcgcatatt
    40741 ggacagcata ttgagccctt cgatatagcc cttaacatga gtcttagggc cagacaagac
    40801 catccaaccc acacggaaac ctgctatgcg gtgggatttt gacagaccat tcatgctgac
    40861 acagaagaca tctggtgcca agctcgccac aggcgtatgc acatgtccgt ccattaccat
    40921 gcggtcatag atttcatccg caaagataat caaatcgttt tgacgggcaa tctcaataat
    40981 ctccagcaag agttccttag gataaagggc tccagttggg ttatttggat tgataaggac
    41041 aattgccttg gtattggaag tgatttttga cttgatatcg tcaatatctg ggtaccattc
    41101 cacagcttca tcacagatat agtgaacggc atttcctcca gctaggctga cagccgccgt
    41161 ccatagagga tagtctggca ttggcactaa gacctcatcc ccattgtcta aaagcccctg
    41221 catggacatg acaatcaact cactgacacc atttccaagg taaatatcat caatatctac
    41281 gtttgggaat ttcttcagct ggcaatactg catgatggcc ttacgggctg agaaaatccc
    41341 tttggagtca gaatagcctt cactatcacg cgcattcata atcaagtcat gaatgacctc
    41401 gtctggcgct gtaaagccaa attctgctgg atttcctgta ttcagacgta aaatcttttc
    41461 tccattcgct cgcatccgca tggcttcttc caatacagga ccacggatat cataagcaac
    41521 atgctctaac ttactagact tgttatattc tttcatcttg tttcctcaat tcatcaggat
    41581 agtaacatta taccactaga aagagaatgc gacaagttta ctgaaatgtg ttactagttt
    41641 cgtatagaag aaaaaccttg ctaaaggcga ggttaagaac gtagagatag caggtatttt
    41701 gcaaagacac atcacatacc aaaagataaa cctagaaaaa gcaagcctag aaaggagtca
    41761 taaagaagat taaacatgag gaaaagcccc catatcatca agtaatccca acgcccactt
    41821 cgttttgcaa ctagaaataa gattagatgg tagagtacat gaaagactaa aaatccaata
    41881 aaacttggat aaagaagcgg taccagactc tctaattgac agatcatgat cacttctacc
    41941 aagactgaaa ctaggataat tccataataa aggaaatttg atttttgaaa agagtttttc
    42001 atcattctcc cttccttcac ttctttcctg ctatcctttc ttttatttta tcatatattt
    42061 atatagagtt taagccctaa tattcttttg aaaaatactt tttttgcttt acttctatag
    42121 tgaaaaggtt tacaattata gtaagaaaat ttcaggaggt ttcattatgg cacaacgtta
    42181 ccaaaatatc atggtcgcaa tcgatggttc taaggaagcg gacttggctt ttgtcaaggg
    42241 agttcattct gctctacgaa acgacgctaa actcaccatc gcacatgtca ttgacacacg
    42301 cgctctccaa agcgtatcca cctttgatgc tgaagtttac gaagaactcc aagtcgacgc
    42361 tgaaagtctg atgaaagagt acgaaaaacg tgctaaagat gctggggtag cagatgttca
    42421 tatcgtcatt gaaatgggaa atccaaagac cctgctagca cgtactattc cagatgccga
    42481 ggaagtggac ctcatcctcg ttggcgcaac tggtctcaac gcctttgaac gcctcttggt
    42541 cggctcttca tctgaataca tactccgcca tgctaaggtc gatttgctgg ttgtgaggga
    42601 acaagaaaaa accttataat cacaaagaaa aggagcccct agctcctttt tgtttacgat
    42661 ttatttctct ctttatggcg ttcgtaagcc ttgagctggc gctgcagttc ctttttaata
    42721 gcaggttctg gagcatattt ttcttcccaa ttatctggtt ttaagatttt atgggtcact
    42781 ggatcaaaat gagccttgcc atctggaaaa attttcccca tattggcctg atggacaata
    42841 tcaaaaatac gttctgggtc cacccccatc aagacaaaac tgccgtaggt gaagtaaagc
    42901 gtgtcaatca aggcatccac ttgccctatc aaatcttgct gagcaggtgt cttcttggct
    42961 actttacctg ctgccttatc aagggcctga tgaagttgcg atacagcttg accaaaatct
    43021 tcttcagaag gactggctgc tcgaacaaac tccaccaatt cttctatttt aaaaccagcc
    43081 ctatgggttg caccctctaa atcccaagct cgaggttctt cttgggttcg ttcatccatc
    43141 atgtggtgga aggtcttgac cttattgaaa tgatagtcac ggctgacaaa gactttttct
    43201 gaagacaaaa caccaaaatg ttccaaggcc ttgtggatcc catcttgttg attgctagtg
    43261 gtaatgtgct tggcagcttc cttgacactg ctactaccat ttcccatagc gaccgacata
    43321 ccgacgccag ccagcatttc aaggtcatta tctgagtcac caaaagccat gacttggttg
    43381 aggtcaaagc catattcttt cccaactcgg cgaatgcctt ctaatttaga atttccctga
    43441 ttgatgacat ccgatgcaaa aggattgcta cgtgtcaatt tcaagtcttc aaaatcagct
    43501 gccgccttct cagattcttc tggtgtcatc agcatcaaaa cttggtagat aggctgattc
    43561 atcaggtgaa gcaggtcctc ttccttttgg ggaacaacct tgctgaccat gcgattaaaa
    43621 gactgactca ccgtccgagt taaaacagag ggaacgaagc gactaattcg ttgggaaaaa
    43681 gaacccagac caaaggacat gattttagaa cccaacatgg catccttggt ccctagagca
    43741 atctccgtgc cctctttttt agcatagcta attagatggc gcaaatgtaa cttggaaata
    43801 gggctcgtga acaagactct gtctttacta aagatatact ggccattata ggttaccgca
    43861 aaatccagat ccaaatcgtc catcaattcc ttaacaaaaa aaggtcctcg ccctgtcgct
    43921 acgccaacta gtaccccttg ttctttgaca atcttaatcg cgtccttagt ggatttcaaa
    43981 acactcttgc gattgttgac caaggttcca tcgatatcaa aaaaaacagc tttgacttcc
    44041 atcctattcc aatctcccct tttgtgatac aatgattata ccacatttca gaaagagtta
    44101 gtaaatcatg cctaagaaaa tccttgtttt acatacgggt ggaactattt ccatgcaggc
    44161 cgatgcttct ggcgctgttg tgacgagttc agataatccc atgaaccatg tgtccaaccc
    44221 acttgaagga atccaagtcc acgccttgga cttttttaac cttccaagtc cccatatcaa
    44281 acccaaacat atgctggtcc tctaccagaa aattaaagag gaagcagata actacgatgg
    44341 agtggtgatc acacacggaa ccgatacttt agaggaaaca gcctatttcc ttgataccat
    44401 ggaagttccc catatgccta tcgttctaac aggagccatg cgtagctcca atgagctcgg
    44461 tagtgatggt gtttataatt acctaagtgc tttacgagtg gccagcgatg acagggctgc
    44521 tgacaaagga gttttggtcg ttatgaacga tgaaatccac gctgccaagt atgtcaccaa
    44581 aacacatacg actaatgtca gcaccttcca gactccaaca catggccccc tcggtctcat
    44641 catgaaacag gaaatcctct acttcaaaac agctgaacct cgtgttcgct ttgaccttga
    44701 tcacatacaa ggtttagtcc ctatcatctc ggcttatgct ggtatgacag atgagctgat
    44761 tgatatgctg gatttagaac acttggacgg tttgattatc caagccttcg gagctggtaa
    44821 tattcccaaa gaaacggctc aaaaattaga aagccttctg caaaaaggaa tcccagtcgc
    44881 tctggtatca cgatgcttta acggtattgc cgagcctgtt tatgcctacc agggtggggg
    44941 cgtacagttg caaaaagcag gcgttttctt tgttaaagaa ctcaacgccc aaaaagcccg
    45001 cttgaaactc ctcatcgccc tcaatgccgg actaacagga caggctttga aagactatat
    45061 ggaaggctaa tactcttcga aaatctctgc aaaccacgtc agcgtcgcct taccgtatgt
    45121 atggttactg acttcgtcag tttcatctgc aacctcaaaa cagtgtgttg cgcagccttt
    45181 aaccagccgc ctagtccgct ctatggtatt cattaagtca acatctcttg tttaagagca
    45241 caaaatcagg aaatcttctc gattccctga ttttttctat ttacgttttc gtgttgagct
    45301 acgttctgtc aaaccatgag gtaagagaac ttcacgttct tccaactctt ccttatgcat
    45361 aatcttggtc aacatacgca tactaatggc accaaggtca taaagaggtt gggcaatcgt
    45421 tgtcaagttt ggacgggtaa agcgtgagat ttgtgaatca tcactagtaa taatttcaaa
    45481 atcttctggc acagaaacac ccttatcagc caaaccgttc aagactcctg ctgccaactc
    45541 atcacctgtc acaactgctg cagttgcatt tgatgaaatc aaacgctctg ctaaggcgta
    45601 accatcatca tagctatatt tagattcaaa taccaaaccc tcactataag cgattcctgc
    45661 ttttttcaag gtttccttgt agccaactaa acgaacctta ccattgatgt catccactag
    45721 cggaccgcta acgaaagcaa tacgctcatt ttctttagca aggtaactca ctgcatcaat
    45781 tgttgcttgc ttatagtcaa tattgacact tggcaactgg tgctcaacat cgacagttcc
    45841 tgcgagaaca atcggagtac gtgaacgcga aaattctgag cgaattttat ctgtcaagtg
    45901 ataacccata tagataatgc catctacctg ctttgaaaag agggtattga caacagaaac
    45961 ttctttctcg ttatcttcat cgctattagc taggacaata ttgtacttgt acatttctgc
    46021 aatatcatca atccccttag ccaaactcga aaaataacca ttggtaatat ttggaatcac
    46081 gacaccgaca gtggttgtct ttttacttgc aagaccacgc gcaactgcat ttggacgata
    46141 atccaaacga tcaattacct ctagcacttt tttacgggta ttctctttta catttttatt
    46201 gccattgacc acacggctga ccgtcgccat ggaaacacct gcttcacgag cgacatcata
    46261 aatggttact gtatcatctg cattcattcc ttttcctgtc ctttctatct cacacattct
    46321 tttacaagta gaggtgctga ttgaagctct atatctactt acaaaagtga agatgtgaaa
    46381 atttcgtttt catatttcta cttattccat tctatcacta attgtaaaca ctttcaagtg
    46441 ttttttgaag attgattgaa aaaatttcat agaaaaccta ggtttagctc cttgctagca
    46501 ccttagacta aacaaaaagg aggaaactaa gccctcctaa agttatagta aaatgaaata
    46561 agaacaggat aaatcgatca ggacagtcaa atcgatttct aacaatgttt tagaagtaga
    46621 ggtgtactat tctagtttca atctactata ggtattgttc cattcactac cgtcaatttt
    46681 agcacatagt cttcatgaaa atattatatc atcataacca accagattct tttgcgatat
    46741 tagctgcctc tgttcgatta ccagcatcca gttttgaaag aatattggtg acatagtttc
    46801 gaatagttcc gtttgagagg taaagctgat ctgcgatttc ttggttggat aagccccggg
    46861 cgattccctt taagacagca atctcttgtt ctgtcaacgg attgggacgg gtcatcacca
    46921 cttccatcaa ttcaggcgaa tactccttgc gtccttcgag gacggtgtgc aaggtttgca
    46981 tgaggtctgc aatgcttcgt tcctttaata cataagcatc cactccagcc ttgaccgcac
    47041 gttcaaaata cccagcacgc ttgaaggtcg tcaccacaac cacctttgtt tcaagctttt
    47101 ctgatcgtat ccactccaag acttcaagac ctgtcttaac aggcatttct acgtcaagga
    47161 tggcgatatc tacagactcc ttttctaata gttggattgc ttcttgccca ttcttggttt
    47221 gaaggacaga ctccacatct ggttgaagcg tgagcaattg acacatggca tctcgcaaca
    47281 tactttgatc ttctgcgact aatactttca tcttagtttc tctccttata aggtagtcga
    47341 acttgcactt ccgttggatg tttctgactg attacactta cttctcctga aaatggaaaa
    47401 acacgatctc ggactgtatg gagctcatct ccttttagaa aagcaaagcc gcagccatca
    47461 tcacttactg ttaaaatgag ttccttctct gtccgttcta attttaagta agctttaaac
    47521 gctttggcat gtttgatgat attggtcacc aactcaagca aaatcatagc agccgtcgac
    47581 tccacatcct gggtcaagct agccttgtct aagtgattct caacttgaac ctcaattcca
    47641 gcaatttcta acatcttttt cacagtctct agttcggatg tcaaagttct agacttaaga
    47701 ttttccacaa tggttcgcac ttcattcatg gaatccttgc tgatctggtg aatttctttt
    47761 aattcctttt ccacctgtgg ataagcctcc atctgaaata actgcaaggc tagatcagtt
    47821 ttaacactaa gcatagcaaa ggtatgcccc agactatcat gcaaatcttg accgatacga
    47881 ttgcgttcat tttcagcaag caatagattt atctgggcat tttgcttagc ctgtgcttct
    47941 ttcaaatcct ccacaattcg aatccgaacc aagccaaaag tcattaaatc gacaaaagca
    48001 agaattacaa gtagatagaa tagaaactca acttcgattc tctgaaaaat caacagttga
    48061 cccacaacaa ggacttgagc aagaagaaaa gtccagacat gtaaagactt taaaccacct
    48121 acgctgaaat gatagcttaa gagattggat aggaaaaaga aaaaccagat ataattaaca
    48181 gccacaaagg cagtattccc aactacataa gtcagcagga tgccccaata tagccaagat
    48241 agacgctggc tcttagttgt taaaacaccc aaatacgcca ctacaaatag aatatcaatc
    48301 aataaatgcc aggcagaaag ccacccaatc actacaggta ggatggggaa aaccataaaa
    48361 attaaactga tccaaaacat ataatgtatg cttttcagtc tttcaagcat taagcattct
    48421 ccttatgacc ttgaaggtaa atggtcaaac caaacaaaac tactgaaaaa acaagtaaat
    48481 aaactgtggc tgatagattg attccacctt catttaagaa ggtcttgatt aattccatca
    48541 actgatatgt tggaagacac ttacccacta cttgcatcca gtctggaaat aaagagatag
    48601 gcatccaaag tccacctaaa acagccaatc ctagataaag aagattaccc acgacagaca
    48661 tcagctgact agtcggtaag agagtcaagg tcaagccaag cgctacaaaa gcaatacttc
    48721 ccacaatcag caaaatcgca gctccaaccc agcttgctag agacatgtcc acacctctta
    48781 caaaatgccc aactgagaaa accaccaaga ttgaaaccaa ataatcaacc agcatacttg
    48841 ttatctttga tagataatat tctaccatat ttacagggct atgacgtaat gttttctgcc
    48901 agttgttcat cttgtcggta tgtaaaacaa ctggaaatga gaagatagct gtcgacatca
    48961 tagaaaaggc agtcatggag ataagataat cacgcataaa attcgcgggt ccacctggtg
    49021 tatcctggta catgctagaa aagaatagat agaaggctgt cggcatccct actgataata
    49081 aataatagac tgattgccgt ttggtcaata gaaattctat cttatttaat gctatccatc
    49141 gtttcatctt agtcatctcc cttttgtgtt tcttcaaaga ttgtatccaa caagctacga
    49201 ttattaactt caatttcttg aatcctacat cctgcttgca ctaacagttg ccaaaaagaa
    49261 tccgcttcac gtgtaactac ttgcagagca tcttgttttt gtacccagtt ttcaaccaag
    49321 actgacttct caacgacttc cttgtaagct agaggaagga taaaatgctt ttcaatctcc
    49381 tcactacgca tagctagagg cgtcgtatca cgaatcaact ctcccttatt taaaaccaaa
    49441 atccggtcag ctgtatgttc tacctcttca atataatgag acgaatagag aatggtgact
    49501 ccttgcgctt ttaggtcccg aacaatttcc caaaaacgtt gacgggtaga ggtatccatg
    49561 gcagcagttg gctcatctaa aaagacaagc tttggtcgac caatcaaggt caagacgaaa
    49621 gaaaagagac gcttttgtcc acctgataat ttttctgcaa attgttcttt ctgttgctgg
    49681 tcaaactgca atagttgatc gatttcctgc tcgctcaagg gatttgggta aatgctttga
    49741 aagaaagcaa tcaactcttt gacctttaat ttctgtacaa tcacattttc ttgagagagg
    49801 taagccctag tatagtctaa cttagaactc gtcactggta aaccttgaat agatacttga
    49861 ccgctggtga ccagtttatc tccgagcaaa cagtccaaaa gtgtcgtctt accagcacca
    49921 ttagggccaa tcaaggcaac gcattcacct tctgctactt caaaggaaat atcctttaaa
    49981 atagccttgc ccttaatatt tttatgtaat ccttgaacct taatcatgtt catgatattc
    50041 tccttccagc aactcctttc ccatcggaaa ggcgataaaa atcataaatc ctaatcccca
    50101 tgcaccacgg atgaactggt gaaggaaggt ttgagcaaac caacctgtaa acatttctac
    50161 cagccatacc aagagtgaca ggccgataaa gaaatagata gttgcttttt tcatttttca
    50221 aactcctttt tcacatctct tactaatttc aaaccttctc tgacaagcca agacatcatt
    50281 ccaaagccag caaagacctc ccaaggaaaa tggtagaaat tctcatccaa tcccgaaaac
    50341 atgagatagg tcataactcc tgctactact aaacttactg cgataatcat tttatttctc
    50401 atctcttctt cccccatttc atactacaat tatagtcttt taaaatcaga ggaggcagaa
    50461 gcttctgtca ctagaaaata tgacaaatgt cataaaaaat tctgttcaaa acaagcaaga
    50521 tacactgtac aataaaacac aatcagaaaa atctaaggca acttcctcaa aagagatatc
    50581 aaacccaatt cacaccataa tgtaaactaa tacttattta aaatcaaaaa gagtagaaat
    50641 ttttatcaga caaacacata tatagtgtat tgaatctata acagtagggc ttaaatacta
    50701 aaatatttct ataaattaat ttaactttcc tgatagagct gttcatatct tatttcaatt
    50761 ctctatatta tacgttgaac aaaacccttc tattgctttc ttaaaaattt ataagagtta
    50821 taaaatctgt taaatttcaa tgtgtatacc taaactacgg tatttattga aaagactggg
    50881 gacaaaaagt atacgctgcc aaaatgaatt actgaaaatc aaaaaagaga gaaccaaact
    50941 gattccctct taatgtatat aatatctagt tttaaaaata cacactcaca tatctctgt
//
LOCUS       DAVKBC010000009        49196 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVKBC010000009 DAVKBC010000000
VERSION     DAVKBC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49196
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.009"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(56..1066)
                     /locus_tag="VWX64_000619"
     CDS             complement(56..1066)
                     /locus_tag="VWX64_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU9190148.1"
                     /translation="MSFLSKNGAGILVCLLISILSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VWX64_000620"
     CDS             1215..2384
                     /locus_tag="VWX64_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9190149.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VWX64_000621"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VWX64_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU9190150.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VWX64_000622"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VWX64_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU9190151.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRVKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETEVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VWX64_000623"
     CDS             4146..4379
                     /locus_tag="VWX64_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9190152.1"
                     /translation="MKEKEIFDSIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4425..4716
                     /locus_tag="VWX64_000624"
                     /pseudo
     CDS             4425..4716
                     /locus_tag="VWX64_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4919..5149
                     /gene="blpU"
                     /locus_tag="VWX64_000625"
                     /pseudo
     CDS             4919..5149
                     /gene="blpU"
                     /locus_tag="VWX64_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
     gene            5864..8017
                     /locus_tag="VWX64_000626"
     CDS             5864..8017
                     /locus_tag="VWX64_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU9190153.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDREFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELVEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8030..9379
                     /locus_tag="VWX64_000627"
     CDS             8030..9379
                     /locus_tag="VWX64_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU9190154.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9549..10256
                     /locus_tag="VWX64_000628"
     CDS             9549..10256
                     /locus_tag="VWX64_000628"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU9190155.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10458..14183
                     /locus_tag="VWX64_000629"
     CDS             10458..14183
                     /locus_tag="VWX64_000629"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU9190156.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISEIRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14276..15718
                     /locus_tag="VWX64_000630"
     CDS             14276..15718
                     /locus_tag="VWX64_000630"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU9190157.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15755..16777
                     /locus_tag="VWX64_000631"
     CDS             15755..16777
                     /locus_tag="VWX64_000631"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU9190158.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGAIGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16774..17319
                     /gene="purN"
                     /locus_tag="VWX64_000632"
     CDS             16774..17319
                     /gene="purN"
                     /locus_tag="VWX64_000632"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU9190159.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            17403..17912
                     /locus_tag="VWX64_000633"
     CDS             17403..17912
                     /locus_tag="VWX64_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9190160.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17937..19484
                     /gene="purH"
                     /locus_tag="VWX64_000634"
     CDS             17937..19484
                     /gene="purH"
                     /locus_tag="VWX64_000634"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU9190161.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAANKYGLTMVFT
                     GVRHFRH"
     gene            19606..20868
                     /gene="purD"
                     /locus_tag="VWX64_000635"
     CDS             19606..20868
                     /gene="purD"
                     /locus_tag="VWX64_000635"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU9190162.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDNFNQAGLKAFGPTRTAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTVATVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKASK"
     gene            21271..21759
                     /gene="purE"
                     /locus_tag="VWX64_000636"
     CDS             21271..21759
                     /gene="purE"
                     /locus_tag="VWX64_000636"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU9190163.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRILSVEDKSIADALANFAEEQGKITEESSNE
                     LI"
     gene            21746..22846
                     /gene="purK"
                     /locus_tag="VWX64_000637"
     CDS             21746..22846
                     /gene="purK"
                     /locus_tag="VWX64_000637"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU9190164.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALADSADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTI
                     VPARISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSI
                     EACDFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYG
                     KIEAKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            22856..23083
                     /locus_tag="VWX64_000638"
     CDS             22856..23083
                     /locus_tag="VWX64_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU9190165.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            23146..24444
                     /gene="purB"
                     /locus_tag="VWX64_000639"
     CDS             23146..24444
                     /gene="purB"
                     /locus_tag="VWX64_000639"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU9190166.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24499..28425)
                     /gene="strH"
                     /locus_tag="VWX64_000640"
     CDS             complement(24499..28425)
                     /gene="strH"
                     /locus_tag="VWX64_000640"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9190167.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPATEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKKIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDIL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEILSQPAPAEESK
                     ALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(28741..29457)
                     /locus_tag="VWX64_000641"
     CDS             complement(28741..29457)
                     /locus_tag="VWX64_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9190168.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29805..31592
                     /locus_tag="VWX64_000642"
     CDS             29805..31592
                     /locus_tag="VWX64_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU9190169.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRNPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31589..32065
                     /locus_tag="VWX64_000643"
     CDS             31589..32065
                     /locus_tag="VWX64_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9190170.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32093..32998
                     /locus_tag="VWX64_000644"
     CDS             32093..32998
                     /locus_tag="VWX64_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9190171.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVAYGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32985..33800
                     /locus_tag="VWX64_000645"
     CDS             32985..33800
                     /locus_tag="VWX64_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9190172.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFASLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33807..34211
                     /locus_tag="VWX64_000646"
     CDS             33807..34211
                     /locus_tag="VWX64_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9190173.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIGGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34505..35671
                     /locus_tag="VWX64_000647"
     CDS             34505..35671
                     /locus_tag="VWX64_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU9190174.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35787..36824
                     /locus_tag="VWX64_000648"
     CDS             35787..36824
                     /locus_tag="VWX64_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU9190175.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37030..37884
                     /locus_tag="VWX64_000649"
     CDS             37030..37884
                     /locus_tag="VWX64_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9190176.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     RGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            38034..38291
                     /locus_tag="VWX64_000650"
     CDS             38034..38291
                     /locus_tag="VWX64_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEU9190177.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(38459..38695)
                     /locus_tag="VWX64_000651"
     CDS             complement(38459..38695)
                     /locus_tag="VWX64_000651"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190178.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDRTDEVSSKHCFEVVDRTDEVS
                     NHIYGKVKLMWFEEIFEEYKSLHNKTHITKVLMN"
     gene            complement(38749..39045)
                     /locus_tag="VWX64_000652"
     CDS             complement(38749..39045)
                     /locus_tag="VWX64_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9190179.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(39035..39196)
                     /locus_tag="VWX64_000653"
     CDS             complement(39035..39196)
                     /locus_tag="VWX64_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU9190180.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            39266..40030
                     /locus_tag="VWX64_000654"
     CDS             39266..40030
                     /locus_tag="VWX64_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU9190181.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            40595..41974
                     /locus_tag="VWX64_000655"
     CDS             40595..41974
                     /locus_tag="VWX64_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9190182.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAQTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIASRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            41988..42653
                     /locus_tag="VWX64_000656"
     CDS             41988..42653
                     /locus_tag="VWX64_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU9190183.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            42767..42862
                     /locus_tag="VWX64_000657"
                     /pseudo
     CDS             42767..42862
                     /locus_tag="VWX64_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            43008..43546
                     /locus_tag="VWX64_000658"
                     /pseudo
     CDS             43008..43546
                     /locus_tag="VWX64_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            43613..44023
                     /locus_tag="VWX64_000659"
     CDS             43613..44023
                     /locus_tag="VWX64_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU9190184.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQENPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            44139..46256
                     /locus_tag="VWX64_000660"
     CDS             44139..46256
                     /locus_tag="VWX64_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEU9190185.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQLALD
                     GNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTININGLISK
                     ETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKAS
                     DKAPWSDNGDAKNPALSPLGENVKTKGQYFYQLALDGNVAGKEKQALIDQFRANGTQT
                     YSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHN
                     HATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASI
                     GFLGLALAGLLGGLGLKNKKEEN"
     gene            46423..47121
                     /locus_tag="VWX64_000661"
     CDS             46423..47121
                     /locus_tag="VWX64_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9190186.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            47118..48170
                     /locus_tag="VWX64_000662"
     CDS             47118..48170
                     /locus_tag="VWX64_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9190187.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            48365..48976
                     /gene="rpsD"
                     /locus_tag="VWX64_000663"
     CDS             48365..48976
                     /gene="rpsD"
                     /locus_tag="VWX64_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU9190188.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
BASE COUNT        13833 a         9524 c        11568 g        14271 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaga
       61 aaatgccgat aagggtctgc ataccaaggc tggtgaggat gatggcaatc cagcagacgg
      121 ctccgagaac aatggatttt ccactggatt tgaccatagc gaccagatta gttttgagac
      181 cgatggcact catggccatg ataatgagga atttagagag ttgtttgaga ggggtaaaga
      241 aactactaga cacaccgaga gaggtcagaa gggtggttag gagcgatgca aggatgaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaagcc ttgcttattt ttttgctcgc
      361 gactttgcca gtaggagaga aagagagtga tggggatgat agctagggtg cgcgtgagtt
      421 tgacaatggt tgcggattcg agggtattgg tctggtagag actgtcccaa gcgctagctg
      481 tggcggttac agaggaagta tcattgaccg cagttcctgc aaagagggcg aagccgtcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggagatggct tgggctactt ccttttcctt agcatggata acaggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaatcaag gtagccagtt
      721 ttgtatccag ggcaaagaag cgctggaaga ggtaggcaac aatcaaggct attgaaatgg
      781 tggaaaggat gacagggagt gaagattgcc caactgcgaa gacttgagag atattgagac
      841 caaaaccaag taagataacg gcatactgga gcaatttctt ggaactaaag gtcaatccaa
      901 catccagttg tttataagac gagagaaagg gatgtaggag catgcccata aaaatcgcaa
      961 aaacgggtgc gccaataaca gggaagaatc ctcctaagta ccaagatagg atggaaatga
     1021 gaaggcagac caagatgcct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 agaatctgtt accattatag acctgtaaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcgggaggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggcta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcgg
     1441 ccagtgattt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaatcttgg
     1501 tcactatcgg agcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtgct cttgccagct cctgcttatc cgggttatga accgatcgtc aatctagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacgggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat ttttgctcct gcgaccttca
     1981 cagcccagtt aatcaagagt caccagtact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaacgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgtctct gtccagagca ttatcatgag gatgagagac gttgccatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaactata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat cgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactctacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attcggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgctttgt tggctgctgg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggacttatgt caacattgcc gactgtagat
     3541 gggaaaggtt ttgacatgct tgacctcggt gctaatgcag aaaatacagc ccagcacctc
     3601 catcaatacg ctgtcctagg ttctttctat gccaagaatg ttcgtggcat tgcgcaacca
     3661 cgtgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagtgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt caaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgccagatt
     4081 cgtaccatgc tagaaacaga agtagttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgaa agaaaaagaa atttttgaca gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgacttggat gctgactcag
     4261 ttgatttgat ggagtttatc ttgacgctgg aggatgaatt tagtatcgaa atcagcgatg
     4321 aggaaattga ccaactccaa agtgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaacttccac gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctgtaat
     4561 catgcgctat ctaaggagag aagcaaggtt gagaatatct ttgccaaagt aaaaacgttt
     4621 aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg
     4681 attgctggta ttatcaatca tgaactagga ttctagtttt gcaggaagtc taatagtaaa
     4741 aaagtgatta gaaaacatct tttttaaaaa tagagatgat tttgaaacaa aaaagctaat
     4801 tcaagacgtt tcgatgccaa ttcaagattt ggatgaaaaa aattaataga tactgttata
     4861 ctaaacttgt caagtttgta acaagacaaa tattaaaaat aaaaaagagg tattcgttat
     4921 gaatacaaaa aagatgtcac aatttgaaat tatggatact gagatgcttg cttgagttga
     4981 aggtggcgga tgcaattggg gagattttgc caaagcaggt gttggaggag gagtagcacg
     5041 aggtcttcag ctaggaatta aaacaagaac atggcaaggt gcagcaactg gtgctgcggg
     5101 aggagctata cttggaggtg tggcctatga agcgacatgt tggtggtaat tatggatttt
     5161 aaaagtttta ttattggttt agtagttggt atatttggtc cttatatgga tgatttaatt
     5221 agaaaaaaat ttttaaagtc ttcggagaag aaaacagaaa aatctgttaa aaaataatca
     5281 aaactataaa tgatgaatct gaatcaaaat tattttgcgc atgtaaagag gagtcttata
     5341 gtaacgagtc aaaaaaggag taactatgaa tcgtaattta gaacggtgtt atctattctg
     5401 actagggata gatcatacca taggtagctt agaaatagca gagacattag aaattgaagt
     5461 aataaatagg atgtcgtaag tgttactatc aatgatttat ttgtttcaag cttgcctagg
     5521 gtgtcagtaa aaaatcattt tcctttcaat agcatatttt tagtgggcag gactcttgtt
     5581 ctgcctattt ttttatccaa aaagtgcagt tgggagggag ataggctcat ttgggaagga
     5641 agtccagttt ttgtttagtg attggggtaa gatagttgtt atcagatgag tttatactct
     5701 tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tatatatgtg actgacttcg
     5761 tcagtcctat ctacaacctc aaaacagtgt tttgagcagc ctgcggctag tttcctagtt
     5821 tgctctttga ttttcattga gtattaggga aaaggagatg aatatgaaat ttgggaaacg
     5881 tcactatcgt ccgcaagtgg atcagatgga ctgcggtgta gcttcattag ccatggtttt
     5941 tggctactat ggtagttatt attttttggc tcacttgcga gaattggcta agacgaccat
     6001 ggatgggacg acggctttgg gcttggtcaa ggtggcagag gagattggtt ttgagacgcg
     6061 agccattaag gcggatatga cgctttttga cttgccggat ttgacttttc cttttgttgc
     6121 ccatgtgctt aaggaaggga aattgctcca ctactatgtg gtgactgggc aggataagga
     6181 tagcattcat attgccgatc cagatcccgg ggtgaagttg actaaactgc cacgtgagcg
     6241 ttttgaggaa gaatggacag gagtgactct ttttatggca cctagtccag actataagcc
     6301 ttataaggaa caaaaaaatg gtctgctctc ttttatccct atattagtga agcagcgtgg
     6361 cttgattgcc aatatcgttt tggcaacact cttggtaacc gtgattaaca ttgtgggttc
     6421 ttattatctg cagtctatca ttgataccta tgtgccagat cagatgcgtt cgacactagg
     6481 gattatttct attgggctag tcatcgtcta catcctccag caaatcttgt cttacgctca
     6541 ggagtatctc ttgcttgttt tggggcaacg cttgtcgatt gacgtgattt tgtcctatat
     6601 caagcatgtt tttcacctcc ctatgtcctt tttcgcgaca cgcaggacag gggaaattgt
     6661 gtctcgtttc acggatgcta acagtattat cgatgcgctg gcttcgacca ttctttcgat
     6721 tttcctagat gtgtcaacag ttgtcattat ttcccttgtt ttattttcac aaaataccaa
     6781 tctctttttc atgactttat tggcgcttcc tatctacaca gtgattatct ttgcctttat
     6841 gaagccgttt gaaaagatga atcgggacac catggaagcc aatgcggttc tgtcttcttc
     6901 tatcattgag gacatcaacg gtattgagac tatcaagtcc ttgaccagtg aaagtcagcg
     6961 ttaccaaaaa attgacaggg aatttgtgga ttatctgaag aaatccttta cctatagtcg
     7021 agcagagagt cagcaaaagg ctctgaaaaa ggttgcccat ctcttactta atgtcggcat
     7081 tctctggatg ggggctgttc tggtcatgga tggcaagatg agtttggggc agttgattac
     7141 ctataatacc ttgctggttt actttaccaa tcctttggaa aatatcatca atctgcaaac
     7201 caagcttcag acagcgcagg ttgccaataa ccgtctaaat gaagtgtatc tagtagcttc
     7261 tgagtttgag gagaagaaaa cagttgagga tttgagcttg atgaagggag agatgacttt
     7321 caagcaggtt cattacaagt atggctatgg tcgagacgtc ttgtcggata tcaatttaac
     7381 cgttccccaa gggtctaagg tggcttttgt ggggatttca gggtcaggta agacgacttt
     7441 ggccaagatg atggttaatt tttacgaccc aagtcaaggg gagattagtc tgggtggtgt
     7501 caatctcaat cagattgata aaaaagccct acgccagtac atcaactatc tgcctcaaca
     7561 gccctatgtc tttaacggaa cgattttgga gaatcttctt ttgggagcca aggaggggac
     7621 gacacaggaa gatatcttac gggcggtcga attggtagag attcgagagg atatcgagcg
     7681 catgccactg aattaccaga cagaattgac ttcggatggg gcagggattt caggtggtca
     7741 acgtcagaga atcgctttgg cgcgtgctct cttgacagat gcgccggtct tgattttgga
     7801 tgaggcgact agcagtttgg atattttgac agagaagcgg attgtcgata atctcatggc
     7861 tttggacaag accttgattt tcattgctca ccgcttgact attgctgagc ggacagagaa
     7921 ggtggttgtc ttggatcagg gcaagattgt cgaagaagga aagcatgctg atttgcttgc
     7981 acagggtggc ttttacgccc atttggtcaa tagctagaaa gaggagagga tgaaaccaga
     8041 atttttagaa agtgcggagt tttataatcg tcgttaccat aatttttcca gtagtgtgat
     8101 tgtacccatg gcccttctgc tcgtgttttt acttggcttt gcaactgttg cagaaaagga
     8161 gatgagtttg tccactagag ctactgtcga acctagtcgt atccttgcaa atatccagtc
     8221 aactagcaac aatcgtattc ttgtcaatca tttggaagaa aataagctgg ttaagaaggg
     8281 ggatcttttg gttcaatacc aagaaggggc agagggtgtc caagcggagt cctatgccag
     8341 tcagttggac atgctaaagg atcaaaaaaa gcaattggag tatctgcaaa agagcctgca
     8401 agaaggggag aaccattttc cagaggagga taagtttggc taccaagcca cctttcgcga
     8461 ctacatcagt caagcaggca gtcttagggc tagtacatcg caacaaaatg agaccatcgc
     8521 gtcccagaat gcagcagcta gccaaaccca agccgaaatc ggcaacctca tcagtcaaac
     8581 agaggctaaa attcgcgatt accagacagc taagtcagct atggaaacag gtgcttcctt
     8641 ggccagtcag aatctagcct actctcttta ccagtcctac aagtctcagg gcgaggaaaa
     8701 tccccaaact aaggttcagg cagttgcaca ggttgaagca cagatttctc agttagaatc
     8761 tagtcttgct acttaccgtg tccagtatgc aggttcaggt acccagcaag cctatgcgtc
     8821 agggttaagc agtcaattgg aatcccttaa atcccaacat ttggcaaagg ttggtcagga
     8881 attgaccctt ctagcccaga aaatcttgga ggcagagtca ggtaagaagg tacagggaaa
     8941 tcttttagac aaggggaaaa ttacggcgag tgaggatggg gtgcttcatc ttaatcctga
     9001 gaccagtgat tctagcatgg ttgcagaagg tgccctacta gcccaacttt atccatcttt
     9061 ggaaagagaa gggaaagcca aactcacagc ctatctaagt tcaaaagatg tagcaagaat
     9121 caaggtcggt gattctgttc gctatactac gactcatgat gccgggaatc aacttttcct
     9181 agattcaact attacaagta ttgatgcgac agctactaag actgagaaag ggaatttctt
     9241 taaaatcgag gcggagacta atctaacttc ggagcaggct gaaaaactta ggtacggggt
     9301 ggaaggccgc ttgcagatga ttacgggcaa gaaaagttat ctacgttatt atttggatca
     9361 atttttgaac aaagagtaat gttcgtgttt ttagagttaa ataattttta aactgtgaga
     9421 aagattcttc ttgcagtttt ttctttacaa tttttgaaaa acatctacta tttattcggt
     9481 taaattcttg tgttttttgg ttttttgtgg taaaatgtgc tcaagtaata cgaaaggcga
     9541 actttaaaat gtcaaaacaa ttgatctatt cgggaaaagc taaagatatc tatacaactg
     9601 aggatgaaaa tcttattatt tcaacttaca aggaccaggc gactgctttc aacggtgtca
     9661 agaaggagca gattgcaggt aagggagtct tgaataatca gatctcatct tttatttttg
     9721 agaaattaaa tgcggctggt gtggcgactc actttgtgga gaaactttca gacacggaac
     9781 aactcaataa aaaggttaag attattcctt tggaagtcgt gctccgcaac tatactgctg
     9841 gttccttttc aaaacgtttt ggtgtggatg agggaatcgc cttggagact ccgattgtcg
     9901 aattttacta caaaaatgat gatttggatg atccatttat caatgatgag catgtgaaat
     9961 tcctacagat tgcgggtgac cagcagattg cctacttgaa ggaagaaacg cgtcgtatca
    10021 atgaactatt gaaagtctgg tttgctgaga ttgggcttaa attgattgac tttaagctag
    10081 agttcggttt tgacaaggat ggcaagatta tcttggcaga cgaattttca ccagataact
    10141 gccgcttgtg ggacgctgat ggcaaccaca tggataagga tgttttccgt agaggattgg
    10201 gagaactaac cgacgtttat gagattgttt gggaaaagtt gcaggaattg aaataatctg
    10261 tttgcaacgg aaaaccttcg tctctcaact aaaaggactc aggctgaaaa ggtcccccag
    10321 accttttcac tctgtagaga actaggtgaa ctaacagatg tttacgaaat tgtctgggaa
    10381 aagttgcagg gtttaaaata acaacctcaa ggctgtttgg gaatattgca agagctgaaa
    10441 taaaggaata agaattgatg gataaacgta tttttgttga aaaaaaggct gattttcagg
    10501 tcaagtcaga gagtttggtt agagagctcc agcacaactt gggactgtca agcttgaaaa
    10561 gtattcgtat tgtgcaagta tatgatgtat ttgacttggc tgaggacttg tttgcacctg
    10621 cagagaagca cattttctct gagcagggaa ccgaccatgt tttagatgaa gtatctgtgc
    10681 aggcggatct tgctaactat gctttctttg ccattgaaag tctgccaggg cagtttgacc
    10741 agcgtgcagc ttcgtcacag gaagccttgc ttttgttggg aagttcgagt gacgtgacag
    10801 tcaacacagc ccaactttac ttggtgaata aagatattga tgcgactgag ttggaagctg
    10861 tcaaaaacta cctgctcaat ccagttgatt ctcgtttcaa ggatatcacg acagggattg
    10921 ccaagcagga gttttcagag tcagacaaga ccattccaaa attgactttc tttgaaagct
    10981 atacagcaga agactttgct cgctacaagg ccgagcaagg gatggccatg gaagtggatg
    11041 atttgctctt tatccaagac tactttaagt caatcgggcg cgtgccaact gagactgaac
    11101 tcaaggtttt ggacacttac tggtctgacc actgccgtca tacgactttt gagacagagt
    11161 tgaaaaacat cgacttttca gcttctaaat ttcaaaagca attgcagtca acctatgaca
    11221 agtatattgc catgcgcgag gaattaggtc ggtctgaaaa accacaaacc ttgatggata
    11281 tggcgactat tttcggtcgt tatgagcgtg ctaatggacg attggatgat atggaagtct
    11341 ctgacgaaat caatgcctgc tcagttgaaa ttgaagtgga cgttgatggt gtcaaggaac
    11401 cttggctcct catgtttaaa aatgaaaccc acaaccatcc aacagaaatt gagccatttg
    11461 gtggagcggc tacctgtatc ggtggagcta ttcgtgatcc gttgtcaggc cgttcctatg
    11521 tttaccaagc catgcgtatt tcaggtgctg gtgatattac agcaccgatt tcggaaattc
    11581 gtgctgggaa attgccacaa caagtcattt ctaaaacagc agctcatggt tattcttcat
    11641 atggtaacca gattgggctt gccacaacct acgttcgtga atacttccac ccaggctttg
    11701 tagctaaacg tatggaactt ggtgccgttg ttggtgcggc tcccaagggc aatgttgtcc
    11761 gtgaaaaacc tgaagcaggt gatgtgatca tccttctcgg aggcaaaaca ggtcgtgatg
    11821 gtgtcggtgg tgcgacgggc tcttctaagg ttcaaacagt tgagtctgta gagactgctg
    11881 gtgctgaggt tcaaaaagga aatgccatcg aagaacgcaa gattcagcgc ctcttccgta
    11941 atggcaatgt cactcgtctg atcaagaagt ccaatgactt tggggcaggc ggcgtctgtg
    12001 tggctattgg tgaattggca gacggtcttg aaatcgacct caacaaggtg cctcttaaat
    12061 accagggctt gaatggtaca gaaattgcca tctctgaatc acaagaacgg atggcggtcg
    12121 tggttcgtcc tgaagatgtg gatgccttcg ttgccgaatg taacaaagaa aatattgatg
    12181 ctgttgtggt ggcgacagta actgaaaaac caaatcttgt catgcactgg aatggtgaga
    12241 caatcgttga cttggagcgt cgtttccttg acaccaatgg tgtgcgcgtg gttgtcgatg
    12301 ccaaagttgt ggacaaggat gtcaaactcc cagaagagcg tcaaacatct gctgaaacac
    12361 tggaatcaga tacccttacg gttctatctg acctcaacca tgcaagtcaa aaaggattac
    12421 agactgtctt tgactgctct gttggacgct caacggttaa tcacccactt ggtggtcgtt
    12481 accaactcac accaactgag gcatctgtgc agaaattgcc agttcaacac ggtgtgactc
    12541 atactgcgtc ggtcattgct caaggtttca acccatatgt agctgaatgg tctccatacc
    12601 acggtgctgc ttacgcggtt atcgaagcaa ctgctcgttt ggtggctgct ggtgccaact
    12661 ggtctaaggc tcgtttctct taccaagaat atttcgagcg gatggacaag caagcagagc
    12721 gttttggtca gccagtagcc gcccttctag gctctattga agctcagatt caacttggct
    12781 tgccatctat cggtggtaag gactccatgt ctggtacctt tgaagaattg accgttccgc
    12841 caaccttggt tgcctttggg gtgacgacgg cagatagccg taaggtgctc tctccagaat
    12901 ttaaagctgt tggggaaaat atctactaca tcccaggtca agccctctct gcagagattg
    12961 attttgactt gattaagaaa aattttgctc agtttgaagc aagccaagct gaccataaag
    13021 tgacatctgc atcagctgtc aaatacggtg gtgtagttga aagtttggct cttgctacct
    13081 ttggaaacta tattggtgca gaggtgacct tgcctgaact taaaacagct ttgacagctc
    13141 aattaggcgg ctttgtcttc acatctcctg aagaaattgc tggagtagag aagattggac
    13201 aaacgaaagc agactttaca ctgactgtca acggtgtgaa gctagatgga cacaagcttg
    13261 acagtgcatt tcaagggaca ttggaagaag tttacccaac agaatttacc caagcgaaag
    13321 aactagaaga agtaccagct gtggcatcag atgttgtgat taaagccaaa gaaaaggttg
    13381 aaaaacctgt ggtttacatc ccagtctttc caggaaccaa ctcagaatat gattcagcta
    13441 aggccttcga aaaagaaggt gcagaggtca atttggtgcc attcgtgacc ttgaatgaag
    13501 aagctattgt caagtcagtt gaaactatgg ttgacaatat cgacaagact aatattctct
    13561 tctttgccgg tggattctcg gctgcggatg aaccagatgg ttcagctaag tttatcgtca
    13621 atatcctgct taatgaaaaa gtgcgtgtgg ctattgatag ctttatcgcc cgtggtggct
    13681 tgattatcgg tatttgtaat ggattccaag ccttagtcaa atcgggtctc ctaccatacg
    13741 gaaactttga agatgctaac agtactagtc caaccctctt ctacaatgat gccaaccaac
    13801 acgtggccaa gatggtggaa actcgcattg ccaataccaa ctcaccatgg ttggctggtg
    13861 tgcaagtggg cgatatccac gctattcctg tttcgcacgg tgaagggaag tttgtcgtga
    13921 cggctgagga atttgcagag ctccgtgaca atggacaaat tttcagccaa tacgttgact
    13981 ttaacggtaa accaagtatg gattctaagt acaatccgaa tggttctgtc catgccatcg
    14041 aaggaattac cagcaagaat ggtcaaatca tcggtaagat gggccactca gaacgttatg
    14101 aggatggtct tttccaaaat atcccaggca ataaagacca acacctgttc gcatcagcgg
    14161 ttaaacattt cactggaaaa taagacttac agattttcta atagatagta tcagtaatgt
    14221 aaaagtcatg taaatctagc tcttgatgat tacaaatgaa aattaggtat aaaaaatgac
    14281 atacgaagta aaatctctta atgaagaatg tggtgttttc ggtatttggg gacatccaga
    14341 tgctgctaag ttgacctatt ttggactcca cagtcttcaa caccgtggtc aggagggggc
    14401 aggaatcctc tccaacgatc aaggacaact gaagcgccat cgtgacatgg ggcttttatc
    14461 agaagttttc agaaatccag ctaatttgga taaattgaca ggagctggtg cgattgggca
    14521 tgtgcgttat gcgactgctg gcgaagcttc tgtagataac atccagccct tcctcttccg
    14581 ttttcacgat atgcagtttg gcttggctca taatggaaat ctgaccaatg cagcctctct
    14641 caagaaagaa ctggaacaaa gaggagcaat tttcagcgcg acttcggact ctgaaatctt
    14701 ggctcacctc attcgtcgca gtcataatcc tagcctgatg ggcaaaatca aggaagcgct
    14761 cagccttgtc aaaggtggtt ttgcctatat cttgctgttt gaggacaagt tgattgcggc
    14821 tcttgaccct aatggctttc gtccgctttc tatcgggaaa atggccaacg gagcggtggt
    14881 tgtttcctct gaaacctgtg cttttgaggt cattggtgcc gagtggattc gtgatttgaa
    14941 gccaggtgag attgtgatca ttgatgacga gggcattcag tatgacagct atacagatga
    15001 tacccagttg gcgatttgtt ctatggagta tatctacttt gcccgccctg attctaatat
    15061 ccacggtgtc aatgtccata cggcacgtaa gagaatggga gcgcaattgg cgcgagaatt
    15121 taagcatgag gcagatattg tagttggtgt gcccaattct tccctaagcg cggctatggg
    15181 atttgcggaa gaatcaggct taccaaatga aatgggtctg atcaaaaacc aatacaccca
    15241 gcgaactttt atccaaccga ctcaagaatt gcgggagcaa ggagtgcgga tgaaactgtc
    15301 tgctgtttcg ggtgttgtca aaggcaaacg tgtggtcatg gtggatgatt ccattgtacg
    15361 tggaacaacc tctcgtcgta tcgttcagct cttgaaagaa gcgggtgcga ctgaggttca
    15421 cgttgccatt ggaagtcctg cactagcgta tccatgtttc tacgggattg atatccagac
    15481 ccgtcaggag ctgattgcag ccaatcatac ggtcgaagaa actcgccaaa tcattggtgc
    15541 ggacagtctg acttatcttt caattgatag cttgattgag tcgattggta tcgaaacaga
    15601 tgcgccgaac ggtggtctct gtgtcgctta ctttgacggt gactacccaa cgcctctcta
    15661 tgactacgaa gaagactatc gtagaagttt ggaagaaaag accagttttt acaagtaggc
    15721 gacagattct ccattaaaga aaaggaaaaa acaaatgaca aataaaaatg catatgccca
    15781 gtcgggtgtg gatgttgaag cgggttatga agttgttgaa cggattaaaa agcacgtggc
    15841 ccgtacggag cgtgcaggtg tcatgggagc tattggtggc tttggtggta tgtttgacct
    15901 ttccaagact ggggttaaag aacccgtctt gatttcaggg actgacggtg tcggaaccaa
    15961 gctcatgttg gctatcaagt acgacaagca cgataccatc gggcaggact gtgtggccat
    16021 gtgtgtcaac gacatcattg ctgcaggtgc ggaacccctc tattttctcg actacgtagc
    16081 gacagggaag aatgaaccag ctaagctaga acaagtggtt gctggtgtgg cagaaggttg
    16141 tgtgcaggct ggtgctgccc tcatcggtgg ggaaacggct gaaatgccgg gcatgtacgg
    16201 cgaagacgac tatgacttgg ctggttttgc ggtcggtgtg gctgaaaaat ctcaaatcat
    16261 tgacggttca aaggtggtag agggagatgt tcttctcgga cttgcttcaa gtgggattca
    16321 ctcaaatggt tactctttgg ttcgtcgtgt ctttgcggat tacacaggtg aggaagtcct
    16381 accagaattg gaaggcaaga aacttaagga agttctactt gagccgactc gtatctatgt
    16441 caaggctgtc ttgccgctca tcaaagaaga gttggtcaac ggcattgccc acatcacagg
    16501 tggtggcttt atcgaaaatg tccctcgtat gtttgcagat gacctagctg ctgaaattga
    16561 tgaaagcaaa gttccagtgc ttccaatttt caaagccctt gaaaaatatg gtcagattaa
    16621 acacgaagaa atgtttgaaa tcttcaatat gggtgtggga cttatgttgg cggtcagccc
    16681 tgaaaatgta gagcgtgtaa aagaattgtt ggatgaagca gtctatgaaa ttggtcgcat
    16741 cgtcaagaaa gaaaacgaaa gtgtcattat caaatgaaaa aaatagcggt ttttgcctct
    16801 ggtaatggct caaattttca ggtgattgcc gaagaatttc cagtggagtt tgtcttttca
    16861 gaccatcgtg atgcctatgt gcttgagcgt gcaaagcagc tcggcgttct gtcctatgct
    16921 tttgaactca aggagtttga gagcaagaca gactacgaag cagcccttgt cgaactcttg
    16981 gaagaacacc agattgactt ggtttgccta gcaggctaca tgaaaatcgt tggaccaacc
    17041 ttattgtcgg cttatgaagg tcggattgtc aacattcatc cagcctactt gccagaattt
    17101 ccaggagctc atgggattga ggatgcttgg aatgctggcg tgggtcagtc tggtgtgacc
    17161 attcactggg tggattcggg tgtggataca ggccaggtca tcaaacaggt tcgtgtgcca
    17221 cgactagctg atgataccat tgacagattt gaagctcgca tccatgaagc agagtacagg
    17281 ttgtatccgg aagtagtgaa ggctctattt acagattgac tttttgatga ttcatatgat
    17341 atctttgatt ttaaattgga gtcagtgttt gttgaagacg gcttcaaacg gaggtatttg
    17401 taatgttaga atctaaaaaa acaactcgat atgtatttta tgtctatctg atgttattaa
    17461 cttggggaat cttatttaag tttgaaacaa atcctgaatt tatagcattt ttcttagctc
    17521 caaggtatat caattggatt ccattttcag aaccactaat agtcgatgga aaaattgttt
    17581 ttgctgaaat gttatttaat ctgatttcct ttattccatt aggtgtttgt ttccctttga
    17641 taaaaactaa tttatctagt ttaagaatag tcgggacagg tttcttgatt agtttattgt
    17701 ttgagtgctt acagtatatt ttagcaatag gtataacaga tataacggat ttgactttaa
    17761 atacgctagg tgtctgtgta ggcttactga tttatcaaat ttttataaga gtgttcaaat
    17821 cacagactag aaaatggatc aatatcttag gtatgcttag ccttggtttt gcttatcttg
    17881 ttttactgtt actgcattta attggtgttt aactaatgat taaaaaggag aatataatga
    17941 ctaaacgcgt cttaatcagc gtctcagaca aagcgggcat tgttgaattt gcccaagaac
    18001 tcaaaaaact tggttgggag attatctcaa caggtggaac taaggttgcc cttgataatg
    18061 ctggggtgga taccattgct atcgatgatg tgactggttt cccagaaatg atggacggtc
    18121 gtgtgaagac cctccaccca aatatccacg gagggcttct cgctcgtcgt gacttggata
    18181 gccacttgga agcggctaag gacaacaaga ttgagctcat tgaccttgtg gtggtcaacc
    18241 tttacccatt taaggaaact atccttaaac cagatgtgac ttatgctgat gcagttgaaa
    18301 atatcgatat tggtgggccg tctatgcttc gttcagcagc gaaaaatcat gccagtgtta
    18361 cagttgtggt agatcctgct gactacgctg tggttttgga cgaattggca gcaaacggcg
    18421 aaacctctta tgaaactcgc caacgtttag cagccaaagt atttcgtcac acagcggctt
    18481 atgacgcctt gattgcagaa tacttcacag ctcaagtggg tgaaagcaag cctgaaaaac
    18541 tcactttgac ttatgacctc aagcaaccaa tgcgttacgg tgagaatcct caacaagacg
    18601 cggactttta ccagaaagct ttgcctacag attactctat tgcttcagcc aaacagctca
    18661 acgggaaaga attgtcattt aataatatcc gtgatgcaga tgctgctatc cgtatcatcc
    18721 gtgacttcaa agatagtcca accgttgtgg ctctcaaaca catgaatcca tgtggaattg
    18781 gtcaagctga tgacatcgag actgcttggg actacgctta tgagtctgac ccagtgtcta
    18841 tctttggtgg aattgtcgtc ctcaaccgtg aggtggatgc tgcgacagct gagaagatgc
    18901 acggcgtttt cctcgaaatc atcattgcac caagctatac ggatgaagcg ctagccattt
    18961 tgatcaataa aaagaaaaac ttgcgtatcc ttgccttgcc atttaatgct caagaggcta
    19021 gcgaagtgga agcagaatac acaggtgtag tcggtggact tctcgtgcaa aatcaagacg
    19081 tggtcaagga aagcccagct gactggcaag tggtgaccaa acgtcagcca accgagacag
    19141 aagcgactgc tcttgagttc gcttggaagg ctatcaagta cgtcaaatca aatggtatta
    19201 tcgtgaccaa cgaccacatg acacttggtg ttggtccagg tcaaaccaac cgtgtggctt
    19261 ctgttcgcct tgccattgac caagccaaag atcgtctgga cggggcggtc cttgcttcag
    19321 atgccttctt cccatttgcg gataacgtgg aagaaatcgc caaagcagga attaaggcca
    19381 tcatccagcc cggtggctct gtccgtgacc aagaatccat cgaagcagcg aataaatacg
    19441 gcttgactat ggtctttaca ggtgtgagac attttagaca ttaagaagat aaaagggaag
    19501 aaaacagttt ctttcctttt ttggcttaaa atgctaactg aaacaagatt aaaacgaact
    19561 tttttgatat aatgttggta aataattcgc aaaagaggtt gaggaatgaa actgcttgtt
    19621 gtcggttctg gtggtcgtga gcatgcgatt gctaaaaagt tacttgaatc aaaagacgtg
    19681 gaaaaagtct ttgtagctcc tgggaatgat gggatgactc tggatggttt ggaattggta
    19741 aatatctcta tttccgaaca ttctaaattg attgacttcg caaagaccaa tgatgttgct
    19801 tggaccttta tcggtccaga tgatgccctt gctgctggta tcgtggataa ttttaaccaa
    19861 gctgggctta aggcctttgg tccgactagg actgcagcgg agctggagtg gtccaaggat
    19921 tttgccaagg aaatcatggt caaatatggt gtttcgacag cagcctatgg cacattttca
    19981 gatttcgagg aagcaaaggc ctatatcgaa aagcatggtg cgcctatcgt agtcaaggcg
    20041 gatggcttgg cgcttgggaa gggtgtcgtc gttgctgaga cggttgagca agcggtcgaa
    20101 gccgctcatg agatgctttt ggacaataaa tttggtgact caggtgcgcg cgtggttatt
    20161 gaggaattcc ttgaaggaga ggaattttca ctctttgcct ttgttaatgg tgataagttc
    20221 tacatcatgc caacggctca ggaccacaaa cgtgcctacg atggcgacaa agggcctaac
    20281 acgggtggta tgggtgccta tgcgccagtt ccacacttac cacagagtgt agttgataca
    20341 gcggttgaca ccattgtcaa gccagttcta gaagggatga ttaaagaagg tcgcccttat
    20401 ctgggagttc tttacgcagg gcttatcctg acagctgatg gaccgaaagt cattgagttc
    20461 aacgctcggt tcggagatcc agaaactcag attatcttgc ctcgcttgac ctctgacttt
    20521 gctcaaaata tcacagatat cctggatagc aaggagccaa atatcatgtg gacggacaag
    20581 ggtgtgactc tgggtgtggt tgtcgcatcc aagggctacc cgctagacta tgaaaggggc
    20641 gttgagttgc cagccaagac agaaggcgat gtcatcacct actatgcagg ggctaagttt
    20701 gcggaaaata gcagagcact gctctcaaac ggcggacgag tttatatgct ggttaccaca
    20761 gtagccaccg tcaaagaagc ccaagccagc atctaccaag aactatccca acaaaaaata
    20821 gaaggactct tctaccgaac agatatcgga agcaaggcaa gtaagtaaag atataagaat
    20881 aacgcgacgc agtcgccaaa cacgataatg gtcgtcgtgg tgaaaagacc agaacagtga
    20941 atgttctggt cagggggaaa ctttgagacc ttaggctcaa agtttaggaa tgaaaccgaa
    21001 ggtttgcttc cgcctccatc acctaagacc attatcaaaa agaaaaaaaa aaattcacaa
    21061 aatacgttaa tggtcgtatg gtttgcgagc gttagcgagc taatatagaa taatcaccgc
    21121 cgttgtgaaa gaacgattgg atgataatcc aatcgttcag ggaaattgga agaccttggg
    21181 tttccaattt aggcatgaga cacctttggt ggctgctgcc gtccctcaca agctaaggtg
    21241 attgttgaaa aagaggaaaa aggagaagaa atgaaaccag taatttccat catcatgggc
    21301 tcaaaatccg actgggcaac catgcaaaaa acagcagaag tcctagaccg cttcggtgta
    21361 gcctacgaaa agaaagttgt ttccgcacac cgtacaccag acctcatgtt caaacatgca
    21421 gaagaagccc gtagtcgtgg catcaagatc atcatcgcag gtgctggtgg cgcagcgcat
    21481 ttgccaggca tggtagctgc caaaacaacc cttccagtca ttggtgtgcc agtcaagtct
    21541 cgtgctctta gtggagtgga ttcactctat tctatcgttc agatgccggg tggggtgcct
    21601 gttgcgacca tggctatcgg tgaagctgga gcgactaacg cagctctctt tgccctccgt
    21661 atcctctctg tagaagataa gtccattgcg gatgcacttg ccaactttgc tgaagaacaa
    21721 ggaaaaatca cagaggagtc gtcaaatgag ctcatctaaa acaatcggaa ttatcggtgg
    21781 cggtcaactg ggtcagatga tggccatttc tgctatctac atgggccaca aggttatcgc
    21841 gctggatcct gcggcggatt gcccggcctc tcgcgtggcg gaaatcattg tggcacctta
    21901 taacgatgtg gacgccctcc gtcagttggc agaccgttgc gatgtcctca cttacgagtt
    21961 tgaaaatgtc gacgctgacg gtttggatgc cgttatcaag gatggacaac tccctcaagg
    22021 aacagatctg ctccgcattt cgcaaaatcg tatttttgaa aaggactttt tgtcaaacaa
    22081 ggctcaagtc actgtggcac cctacaaggt cgtgacttct agcctagact tggcagatat
    22141 cgacttgtcg aaaaactatg tcctcaagac tgcgactggt ggctacgatg gtcatggaca
    22201 aaaggttatt cgttcagaag tagacttgga agcagcctat gcgctagcag actcagcaga
    22261 ctcagcagac tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt
    22321 gtcaggaaat ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa
    22381 tatcctgtct aagaccatcg taccagcccg catttctgaa agtctagtag acaaggctaa
    22441 agctatggca gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat
    22501 gtttgcgact gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg
    22561 gcactattct attgaagcct gtgatttctc tcagtttgac acccatattc tcggtgttct
    22621 cggagcacca ttaccagtca tcaaactcca tgcgccagcc gttatgctta atgtcctcgg
    22681 tcagcatgtc gaggctgctg agcaatatgt gacagaaaat tcaagcgccc acctccacat
    22741 gtatggtaaa atagaagcga agcacaaccg caagatggga catgtgacct tgtttagtga
    22801 tgtaccggat agtgtggatg agcttgggga agggattgat ttttaggaca agtctatgat
    22861 acaaattatc gttaatacat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt
    22921 gtatgccagt gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata
    22981 ccccgaaaat tatttagcta tctatgatgt accgctggat acggatttga atacactaga
    23041 tcattacccg tctgtgttta ttgaaaaaga ggagtttgag tagaattctt ggtttaccta
    23101 gatagcttat tcccaacagc ttaagaagaa aggaaaaatt aacacatgat caaccgttac
    23161 tctcgccctg agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag
    23221 gtggaaatcc tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg
    23281 gctttgattc gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag
    23341 acgcgccacg atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc
    23401 aagtgggttc actatgggtt aacttctacc gacgtggtgg atactgctta tggttacctc
    23461 tacaagcagg ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct
    23521 gacaaggcca aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct
    23581 gagccgacaa cctttggtct taaattagca acttggtaca gcgaaatgaa acgcaatatc
    23641 gagcgcttcg agcatgcggc tgctggtgta gaagctggta agatttctgg tgcggttggg
    23701 aactttgcca atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt
    23761 gcccaagaaa tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt
    23821 cttgccagca ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa
    23881 tctgagcaac gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg
    23941 cctcacaaac gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt
    24001 ggtcacatga ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac
    24061 tcatcagctg agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac
    24121 cgttttggaa atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg
    24181 aactcgactt ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc
    24241 atgacccgtg agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac
    24301 caagtagact ttaaaccact tcttgaggca gattcagaag taacatcacg tctcacacaa
    24361 gaagaaatcg atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt
    24421 gaacgtcttg gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt
    24481 attttttatc gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt
    24541 ggccatgagt cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt
    24601 tttctctatt accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc
    24661 tggttggctt aggatttcta gttttggttt ttcttcagca atagcggctt gtccgttttc
    24721 atcgcctaca tgtgttacca tagttccgac ttcgactatt tgagtaacgg cttcctgtgc
    24781 tacgacacta tttacaagtg ttttcacttc cttaccatcg gcagaagtgc tcacagagta
    24841 gaagttgcta cgatgtccat tgacaccctt agtaatgact tgtgtttttc ctttgagtaa
    24901 gagtggattt tcacgagtca ctgtggtaaa tggaatttct tcttcttgga tatccagtct
    24961 aggttttacc tcagtagttg gtgcaagacc actttcatca cccttgtgag ttacaggagc
    25021 gccaacttca accacttggt ttataacttc tttggttacc tggctatcaa ggactgtttc
    25081 tgttgttttt ccattttcag tgagtacaga gatgtaatga gttcgttcac ctttgactcc
    25141 tgctgtgata atattttcct gaccagctgg gaggttagga ttttctttct tgataacttc
    25201 aaatggaatt tcttcagttc ttgtgatgag ttctggtctg gtttcaacat tggcagccac
    25261 ttcattttca tccaggcttc ctgaatgagt tgcagctggt ttgaggcctt gaagagcggc
    25321 ttttaggttg gctacaagta tgtcaagctc agcttgttta ttacggttga ggttgtaatt
    25381 tagagctgtt ttagctgcgt caagggcctc aagactttct ttactatatc cttctaagtt
    25441 tgtaggaatt ttagctaatt cttcgcggag agcattataa ttagcacgga agtagtcttt
    25501 gttgtggtct gcaaaggcag tcatgagttc aaagatttcc tcttccttgt actcagcgct
    25561 tggtctatct gcccagattg aaagcatact tccgactgtt ggaagatcta cttcaggata
    25621 tttggtagaa gctagttgat tgaatggtgt ttttccagta ttctcaatag ctttcttgag
    25681 gaaaccacca ccatcttctg gtttttgacc aagaatgtag taccagtcac cgttggtatt
    25741 caagaattta tagcctttgc ttgctaggta ttgaggtgat gcgaggttat atccccacca
    25801 gcctttagac cagtaagaaa tcaagacatc tttgtcaaac tgaacatcgt ccttgtcttc
    25861 atagtagaag ccatcgttga aggccattgg ttgaagccct ctttctttgg ccatagctgc
    25921 gagggtgttg gcatattcgg caaatttgcc atagagttga taccacttga ggtagtacca
    25981 gccttgggca ctagtcgcat cgttggcgta ttcgtcagta ccaaagttga aaatctttgt
    26041 tttacctgca aagaagtcca tgtatttacc gatgagggct tttacaaagt tcatcgcttc
    26101 ttcgtttttc aagtccatag ttgtttttga aactttatca aagtgggctt gaggattttt
    26161 aatacctaat ttttccatgg caaccagcat agcatccatg tgacctggac tgttaatagc
    26221 tgggatgaga ccgatgtcct tagatttagc gtattcaatt agctctgtca cttctgcctg
    26281 tgttagtgca gtaccgtttg gatcgtcgta gtaagcttta gttccttcga taatagcttt
    26341 tttaacgtca tcactagcat aggtttttcc gttggcagta atggtcatat catcgagtag
    26401 aaagcgaagt ccgtcatttc ctagaaggag atggacatca gaatatccga gctcactggc
    26461 cttgtctacg atgcgtttga gctggttcag agtaaagtat ttgcgtccag catcgattga
    26521 gattaccttg tttttggcaa gtttttcaac ctcacgttta gcttcttctt ctttttgagc
    26581 ttcaggcgtg agggtcaagt tgttgacagt ttcttgaagt ttagcaatgg cttgatcaat
    26641 cgtatcttgt tgggcacggc taaggttgct atcgagagag cgaatagctt tttcagcttc
    26701 ttttacggcc gtgacgcttt ctgcagtata acggttcagg tcttttggta cctcgttaag
    26761 tgcttgctct gcagattcat aatcagctgc gaagtattca gcgttggcat ttgcaaaatg
    26821 acgcatgagt ttgaagaggc gtgatggtga ataacgtgca gatggagtgt cagcccaagc
    26881 agctaccata ccaccgatga ttgggatatc agctccttct gtttttggta cagaagtgat
    26941 tggtgtgttt ttaataccat tgagcccctg atcgagattg taccagcctt ggccatcagc
    27001 gtttcgtcca agaacgtagt accaagcatc attggtatta aggatttggt gacctttttc
    27061 agctagtagt ttagaagaag cgacatcgta gcctccccaa ccaccagtcc acatagaaac
    27121 gatgatgtct ttgtcaaaac taccaaagct tgtgtcgcta ttgtagtaga taccgtcgtt
    27181 aaaggccatt ggtttgagac cgtgcgattt tacaatacga gcgaggtcat tggcgtaggc
    27241 aataaatttt tcatagcctt ttacagggta gccttcgttt ggatagtatt tatcagcttg
    27301 aagcacactc caacctttag catctgtcgc atcattggca tattcatcaa gtccgatgtt
    27361 gaagatttca gtctttttcg cgaaataagc agcatacttg tcgataaggg cttttgtaaa
    27421 agcgacagct tgttcgttgt caagatcgac agtacgggct gattccttcc caaaatagct
    27481 aaagttaggg ttttggattc ccaattcttt catggcattg agaatcgcat ccatgtgacc
    27541 aggactattt actgtcggaa tgagaccgat acctttatct ttggcatagt taatcagatc
    27601 tgtcatttga ctttctgtta agtgattgcc gtttggatcg ttgtaataat catttgtacc
    27661 tttttcaatg gcgcgtttga catcgtcact ggcataggtc ttgccgttag ctgtgatgct
    27721 catatcgtcc aacatgaaac ggagtccatc atttccgact aataggtgta aatcagtgta
    27781 gccataatgt ttcgctttat cgatgatttt cttgagctgt tctggtgaga aatatttacg
    27841 tccagcatca atagaaacaa ttttcttttt cgctagtttt tcatttacag ttgcagcacg
    27901 ttcctttcct gcctctgttg ccggtttgtc agcctctgct ttcgcttcat cttttttagc
    27961 tggtttatcc ttgtcagtct tgtctgtatt tgactcttta gaatcaacct ctttcgcttc
    28021 ttccttttta gggctagctt cttctgcctt tttattagca gtttcttttt cagcagaagt
    28081 tggagttacc acttctgctt tatcactagg agttgaacta acttcctctt gtggtttttc
    28141 ttctgttttt ggaagactag ctaccttatc agtagctgga gtttctgttt ctacagtttt
    28201 tggagcttct ggttgaagct ctgctttagg tgtttcctca gtccgatttt cggatgattg
    28261 aggggaatca gaaaccgtat ggatggtcgg ttggttttct gtagtagtag gagtaactcc
    28321 atcggctgca acagtctgtg cttggaaggc aaatccaatt agaacagaag ctgctcctac
    28381 agcgtattta cgaatagaaa aacgctgttg tttttcatgt ttcattgcaa aacctcctga
    28441 ttgcattgtt atattgatag cgattatata aatcaacgcc cttattttat ttcttatatt
    28501 aacgagagtc aagaggagat gacaaaaaac tataataagt ataaaaaaat ataaaattta
    28561 aacttaagat ttcagattgg tcggaaaaaa tgcatatata tatctaatat aatttttggt
    28621 tctatttcta taaaatattc cacaaattat agaatcttcc aaaaataggt aagcgctacc
    28681 tttttggtgt ggtataataa gcatagaaaa agcccgagcg attaggctca ggctttcttc
    28741 ttagtgatca cggtcacatg agatgaattt aatcttgtag taatcagatc gtttgtaagt
    28801 ttcactgtat tctaaaactt ggccagttga ttcgagtttg gtgattttag tttgtaggac
    28861 agtagggaat tgttcatcga ctccgaggac tgaagccgca tgttctggag ttggaaagac
    28921 tatttcgttg atttcttcaa agtgttcatc attcatgtga atgtggtagt ctaacttgaa
    28981 acgattatag atagaactat agtattcaag gtttggataa tttgcgttga tatattgttc
    29041 tgggatgtag gatgtatggt agatataaac gacaccgttt gattcgcgga tacgttcaat
    29101 cttgtagtag aattgatcgc cacgtagacc caatttttcc aagtaaacaa gcttgtttcc
    29161 gcgttcaatt gaaagaacag ttaccttatc atctttagca ttgaagagtt caatatctga
    29221 aaactctaca agcttgtgtt tgcgtgcacg tgaaacgaag gttccttttc cttgttggcg
    29281 gacaatatag ccatctttgg caaggtcgtt taaggcgcga acaactgtga tagagctgac
    29341 atcgtacatt gaaatgagtt ctgcttcagt gtaaaattta tctccactgc taaactgccc
    29401 agagatgatt ttatttttta attcgtcttt tatgtattga tatttgggaa ttgccatatt
    29461 tttacctcta ttttccttct ccatagaaaa ttttaccata aaagcgaaaa aaatagtagt
    29521 cttttgaata aaaaattaga ataatagttt gaaaaattaa gcgatatagg gattgctcat
    29581 attttatcaa tgtattctat acaaaattat tttatgtcct atattccgaa tttaaagagc
    29641 gtttgaaatg ggtctaaaaa tgtttgaaac taattgaatg tgtgtataat agtaaaaatg
    29701 cagtaaatat cccgacaatt tctattgaca attcaaacag attggtttat aattaatata
    29761 acaacaaatg aaagcgcaaa ctttcgtggt cggaaggtag ttttatgaca cgatttgaga
    29821 tacgagatga tttctatctc gatggaaaat catttaagat tttatctggt gccattcatt
    29881 attttagggt tcctccagag gattggtatc attcgctcta taacttgaag gctcttggtt
    29941 ttaatacggt agagacttat gttgcttgga atttacacga gcctcgtgaa ggtgagtttc
    30001 attttgaagg tgatctggat ttagagaaat ttctccaaat agcgcaggat ttgggtctct
    30061 acgcaattgt gcgtccgtct ccatttatct gtgcggaatg ggaattcggt ggcttaccag
    30121 cttggctctt gaccaagaac atgcgaattc gctcatccga cccagcatat atcgaggcag
    30181 ttggtcgcta ctatgatcag ttattgccaa gactggtgcc tcgtttgttg gacaatggtg
    30241 gcaatattct catgatgcag gttgaaaatg agtatggttc ttacggagaa gataaggctt
    30301 acctgagagc gattcgacag ctaatggaag agtgtggcgt aacctgtccc ctctttacat
    30361 cagatggtcc gtggcgagct actctgaaag ctggaacctt aattgaagag gacctctttg
    30421 taacaggaaa ctttggttct aaggcacctt acaacttttc gcagatgcag gaattctttg
    30481 atgaacatgg taagaaatgg ccactcatgt gtatggagtt ctgggatggt tggttcaatc
    30541 gctggaaaga accgattatc acacggaatc ctaaggaatt ggcagatgca gttcgagagg
    30601 ttttggaaca aggctctatc aatctttaca tgttccacgg tggtacaaac tttggtttca
    30661 tgaatggttg ctcagctcga ggaactttgg acctgccaca agttacgtct tatgattacg
    30721 atgcccttct ggatgaagaa ggaaatccaa ctgctaaata tcttgcagtc aagaagatga
    30781 tggcaacaca tttttcagag tatccgcagt tggaaccact ctacaaagag agtatggagt
    30841 tggatgctat tccactagtt gaaaaagttt ctttgtttga aaccttagat agcttgtcaa
    30901 gtcctgtaga aagtctctat cctcaaaaga tggaggagct gggacaaagt tatggctacc
    30961 tactttatcg aacagaaaca aactgggatg cagaagaaga aagacttcgt atcattgatg
    31021 gtcgagatag ggcccagctg tatgtcgatg gtcagtgggt taaaactcaa tatcagacag
    31081 agattgggga agatattttt tatcaaggta aaaagaaagg gctatctagg ttagatatct
    31141 tgatagaaaa tatggggcgt gtcaactatg ggcataagtt cttagcggat acgcaacgta
    31201 agggaattcg gacaggggtc tgtaaggatc tgcatttctt actaaactgg aaacactatc
    31261 cactcccact agacaatcct gagaaaattg atttttcaaa aggatggact caaggacaac
    31321 cagcctttta cgcttatgac tttacagtcg aagagccaaa agatacttac ctagacttgt
    31381 ctgagtttgg taagggggtt gcctttgtca atgggcagaa tctaggacgt ttttggaacg
    31441 ttggcccaac tctctcactt tatatccctc atagctatct caaggaaggt gccaaccgca
    31501 tcattatctt tgaaacagaa ggtcaatata aagaagagat tcatttaact cgtaaaccta
    31561 cactaaaaca tataaagggg gaaaacttat gacaattgta ggatgccgta ttgatggacg
    31621 tttgatccac ggacaagtag ccaatctttg ggctggaaaa ctaaatgttt cacgcattat
    31681 ggttgtagac gacgaagttg tcaacaacga tattgaaaag agtggtttga aacttgcgac
    31741 accaccaggt gtgaaattga gtattttgcc agttgagaaa gctgcagcca atattcttgc
    31801 tggcaaatac gatagccaac gtctctttat cgtggctcgt aaaccagacc gcttccttgg
    31861 tttggtagaa gcaggtgtac cacttgaaac ccttaatgtt gggaatatgt ctcaaacacc
    31921 agaaactcgt tctattacac gttctatcaa cgtagtagac aaggatgtgg aagacttcca
    31981 caaactggca gaaaaaggtg ttaaacttac tgctcagatg gttccaaatg atccaatttc
    32041 agactttttg agcttattaa aataggaaaa aaatttttag gaggtcattg ttatgataca
    32101 atggtggcaa attttacttc tcactttgta ctcagcttat caaatctgtg atgagttgac
    32161 gatcgtttca tctgcaggtt cccctgtatt tgctggtttc attactggtt taatcatggg
    32221 agatgtgact actggtttac ttatcggtgg taacttgcaa ctgttcgttc ttggggttgg
    32281 taccttcggt ggtgcttctc gtatcgacgc aacttctggt gcggttcttg cgacagcctt
    32341 ctctgtttca caaggaattg atgcaccgct tgccattact acaatcgctg taccagtagc
    32401 agctctcttg acttacttcg acgttcttgg tcgtatgact actaccttct tcgctcaccg
    32461 tgtggatgct gcaatcgaac gctttgacta taaaggtatt gaacgcaact acttgcttgg
    32521 tgcgattccg tgggctctat ctcgtgccct tccagtcttc tttgcccttg cttttggtgg
    32581 tgcctttgta caatcagtag tagacttcgt tgaagcctac aaatgggttg catatggctt
    32641 gacacttgca ggacgtatgc ttccaggtct tggatttgca atcttgcttc gttaccttcc
    32701 agttaaacgt aaccttcact accttgctat gggatttggt ttgacagcta tgttgactgt
    32761 tctttactca tatgtaacag gtcttggtgg cgctgttgct ggtatcgtag gtactcttcc
    32821 tgctgaagtt gctgaaaaaa ttggtttcgt gaacaacttc aaaggtttgt ctatgattgg
    32881 tatttctatc gtaggtattt tccttgcagt gcttcacttc aaaaatagcc aaaaagtagc
    32941 tgtagcagca ccttctacac catcagaaag tggggaaatc gaagatgacg aattctaatt
    33001 acaaacttac aaaagaagat tttaatcaaa tcaacaaacg tagcttgttt actttccaat
    33061 taggttggaa ctacgaacgt atgcaagctt ctggttacct ttacatgatc ttgcctcagt
    33121 tgcgtaaaat gtatggtgat ggaactcctg aattgaaaga aatgatgaaa gttcatactc
    33181 aattcttcaa tacttcacca ttcttccata ccattatcgc tggttttgac cttgccatgg
    33241 aagaaaaaga tggtgtaggt tcaaaagacg ccgttaacgg tatcaagaca ggtttgatgg
    33301 gaccattcgc tcctcttggg gatacaatct ttgcttcact tgtacctgct atcatggggt
    33361 cagtcgcagc aactatggct atcgctggcc aaccttgggg gatcttcctt tggattgcag
    33421 ttgcagtagc gtatgacatc ttccgttgga aacagttgga atttgcttac aaagaagggg
    33481 ttaaccttat caacaacatg caaagtacct tgacagcttt gattgacgct gcatctgtac
    33541 ttggtgtctt catgatgggt gctcttgtag caacagtgat taactttgaa atttcttaca
    33601 agttgccaat cggtgaaaag atgattgatt tccaagacat cttgaatcaa atcttcccac
    33661 gtttgcttcc agcaatcttt actgccttta tcttctggtt gcttggtaag aaaggtatga
    33721 actctactaa agctatcggt attattatcg tacttgcttt ggctctttct gcccttggtc
    33781 actttgcact tggaatgtaa ttccttatga ctaaatcatt aattttggtg agccatggtc
    33841 gcttctgtga ggagcttaga ggtagcacag aaatgattat gggcccacaa gacaacattt
    33901 acacagtagc tcttcttcca gaagatggcc cagaagaatt tactgctaaa tttgaagctg
    33961 ttattggagg attggatgat ttcctagtct ttgcggatct tctcggtggg acaccttgta
    34021 atgtggtgag tcgcttgatc atggaaggtc gtgatattga cctttacgca gggatgaatc
    34081 ttccaatggt gattgaattt atcaatgcga gccttacagg cgcagatgcg gactacaaga
    34141 gccgtgctgc agaaagcatt gtgaaagtta atgacctgtt agcgggcttc gatgatgacg
    34201 aagatgaata atactcttcg aaaatctctt caaactacgt caacgtcgcc ttgccgtagg
    34261 tatatgttac tgacttcgtc agtcttatcc ggcaacctca aaacggtgtt ttgagctgac
    34321 ttcgtcagtt ctatctgcaa cctcaaagca gtgctttgag cagcctgcgg ctagtttcct
    34381 attttagttg gaactcgatt caattcatgt gacaacgtga aaatcgttag agcattttat
    34441 atagaatata catgggaatg gagcttactc ccattcccat atttaataga aaaagaggaa
    34501 ctcaatgcta cattatacaa aagaagactt gctcgaattg ggtgcagaaa tcactacgcg
    34561 tgaaatctac caacagcctg atgtatggag agaagctttt gaattttatc aagcaaaacg
    34621 tgaagaaatt gcagccttcc tacaagaaat cgctgataaa catgactata ttaaggttat
    34681 cttgacaggt gctgggactt ctgcttatgt gggagatacc ttgctacctt actttaagga
    34741 agtctatgac gaacgcaaat ggaatttcaa tgctattgcg acaacagata tcgttgccaa
    34801 tccagcaacc tatttgaaaa aagatgtggc aactgtcctt gtgtcttttg ctcgtagtgg
    34861 gaactcgcct gaaagtgtgg cgactgttga tttggccaaa tccttggtgg atgagcttta
    34921 tcaagtgacg attacttgtg cagcagatgg taaattggct cttcaagctc acggtgatga
    34981 ccgtaatctc ttgctcttgc aaccagctgt ctctaatgat gctggatttg ccatgacttc
    35041 tagctttacg tctatgatgt tgacagctct cttggtcttt gatcctacag aatttgctgt
    35101 taagtctgaa cgttttgaag ttgtatctag tcttgcccgt aaagttttag acaaggcaga
    35161 agatgtcaaa gagctcgttg atttagactt taaccgtgtc atctatctag gcgctggtcc
    35221 tttctttgga cttgctcatg aagctcagct caagattttg gaattaactg ctggtcaagt
    35281 tgcgaccatg tatgaaagcc cagttggctt ccgtcacggt ccaaaatctc ttatcaacga
    35341 caatacagtt gttttggtct ttggtacaac gacggactac actcgtaagt acgacttgga
    35401 cttggttcgt gaagttgctg gtgaccagat tgctcgtcgt gttgtgcttt tgagtgatca
    35461 agcttttggt cttgaaaatg tcaaagaagt ggcccttggt tgtggcggtg tcttgaatga
    35521 tatttaccgt gtcttccctt acatcgttta tgcccaactc tttgccctat tgacttcact
    35581 caaggtagaa aataaaccag atacaccgtc tcctacaggt acagtaaacc gtgtagtaca
    35641 aggtgtcata attcacgaat atcaaaagta agacagtgtt tatgaattct tgacaagagg
    35701 atttgtaaat tatcagataa accatagatt gtcagtacgc tttctatggt ttgtttgctt
    35761 gagagaaata gtaaaaggag aacagaatga aagcatacac agagcgtgta tttggaaatg
    35821 ttgagggtga ggatgtcttg gcctatcgat ttgagacaga cggtggctac caacttgagg
    35881 ttatgactta tggtgcgact atcttgcgct atgtcgcacc tgacaaggct ggaaattttg
    35941 ccaatgttat cttgggattt gatgactttg atagttatgt aggcaatagt cccaagcatg
    36001 gagcaagtgt aggtcctgta gcgggtcgta ttgcaggtgc gacctttgag ctcaatggta
    36061 agacctatga ccttgaggtt aataatgcta gcaactgtaa tcacagtggt tcaactggtt
    36121 gggattccag cttgtttgaa gttgaagaag taagcgatca tggcttgact ctctacacag
    36181 agcgtacaga tgggacagga gggttccctg gaaatctcaa gatttggatc agttatcact
    36241 tggaagaaac tggtgcctat gaaatcagct acaaggtaac gaccgatcag gatacgctgg
    36301 tcaatccaac caaccacagc tatttcaact tgtctggtga tttcacgcag acgattgacc
    36361 gtcatgtctt ccaactaaac acagagggca tttactcaat cgctcctgac ggtgttcctg
    36421 ccaaaactcc agaagccaac cgtgatgtgg tcaaacacat ctacaatggt gccttgttga
    36481 aggatatctt tgcagaagaa gatgagcaaa tccagctggc atcaggtttg gatcatccat
    36541 ttgcccttcc tgcaggccat gacaatgctg gattccttta tgaccaaaat tcaggtcgct
    36601 tcctgctttt caagacagaa gctccttgct ttgtggtcta cacagcaaac tttgtggatg
    36661 aaagtgtcat cataggaggt cagccaatgc tacagcacaa tgggattgct cttgaagcgc
    36721 aagctttacc agatgccatt cacagtgacc ttaaaggcca agtcattctt aaagctggtc
    36781 aaaccttcac cagtaagaca cgttatgaac ttgttgtgaa ataaaaaagc tggtcaaaaa
    36841 gtctttaaat taaaataacg catattgtca ggtgatgaaa agtttgataa tatgcgtttt
    36901 attatgaaat gatttacttt atcttatcct gaaatggtgt tatttttgag ttatctggct
    36961 tgactttctt gatggaaatt atataatagt tgtaataaca ataattacaa cgagaaaaga
    37021 ggaccattta tgacctatga atacaagagt cacatttatt tggcagagac agttttaaat
    37081 gtaaaggatt tggccagtca aacagccttt tatcagcaag ttattggttt agaaatctta
    37141 tctcaaactg agacagagtc cattctaggc cttggtggaa aagtcttggt acagctgatt
    37201 caagcacaag agagcggaga agtgagggaa cattatggtc tttaccattt ggccattctc
    37261 ttgcccacac gcaaggcttt ggctgatgtc ttgaaacatc tgacagattt gcaaattcct
    37321 cttgtcggcg gtgcagacca tggttacagt gaagctattt acttggaaga tttggaggga
    37381 aatggcattg aactctatcg agataagcca gtttccacat gggatattcg agaagatgga
    37441 cgcattatcg gagtgacgga ggctcttgcg gcgcaggaca tttatgagtt gggggaaaga
    37501 gtagagccct ttatcctggc agaaggtaca agaatggggc atattcatct ttccgtcaag
    37561 gatagtcgaa agtccagcca gttttatcaa aaggtgttag ggctagagaa taaattcagt
    37621 gtgcctggcg ctagttggat tgcggctgga gattaccatc atcatttagc agttaacgaa
    37681 tggagaggaa aaggtctggc ttcgcgtaag caaggcttac caggtttagc ctactatgtc
    37741 atcgaagttg cacataaaaa agaactgtta acgattgccc aacgagcaca agaagttgac
    37801 gcaccaatca aatggatgac atcgagcaaa ttggaaatca cagactcaga tggcatcgtg
    37861 acccgtattc gtttagcaag gtaaaattag gaatttttaa taagttataa gtattgctag
    37921 tttgcttttt gaacggtctt tggtaacaga actgcgtgag ctggatgggt gagaattttg
    37981 acaaagaagc tgattagaga tataatgaag aaaaatcgag caaggaaaaa gaaatgacaa
    38041 attcaaagta tattacttgt ttgaaacgtt cagagggcca gttgtgtggg attcaaaaga
    38101 tgattgaagg agatcgtgac tgtgctgata ttgtgacgca actgacagca gtgagatcta
    38161 gtgtagagcg cgtgattgag atgataatta ccgaaaatct tactgaatgt atcaatcagc
    38221 cactagatga ttctgaagct caaaaggaac gcctagaaaa ggctatccga tacttgatta
    38281 aacggaaata aatgaatgtt ttgagacgat atgtgcaaag gtctattaac tattagaata
    38341 gtttaatgtg agtcaaaaga agttgtaaaa aatctttaaa attaaaaaaa cgcatagtat
    38401 caggtgttga atgtactgac ccccaaaagt tagatttttt ctgtctaact tttgggggtc
    38461 agttcataag aaccttggta atatgcgttt tattatgtag agacttatac tcttcgaaaa
    38521 tctcttcaaa ccacatcagc ttcaccttgc cgtagatatg gttactgact tcgtcagttc
    38581 tatccacaac ctcaaaacag tgttttgagc tgacttcgtc agttctatcc acaaccttaa
    38641 aacagtgttt tgagcagcct gcggctaact tcctagtttg cactttgatt ttcattgagt
    38701 attacttcat cttttcctga aattgagttt ttgcccagct cctcttgatt attctacttg
    38761 accgggccaa gcattcatac caccttctac gttggtaacg gtgaggcctt gggagctgag
    38821 aaattggcag gtagatgcag agcggactcc tccttgacaa atgacatagt attcatggtc
    38881 aggtttgagt tctttgtagc cttgctctaa ggtacttaat ggaagatttt tggcacctgg
    38941 tgcatgtcct gcttggaatt catgtgcttc acggacatcg ataagttcta gattttcatt
    39001 ttggtatttt ccataaaagt cagccatgct gatactagtt tccatattct actccttctg
    39061 ggttaaccat tttgtatagt gaataagcgc cgtcaaggtt ttgggcggta aatcctgctt
    39121 gcttgaggat aggctctgcg atatagctgc gcaaaccact gtggcagctg acgatgtagg
    39181 cttgtttttt gtccagttca tcagcttcct ccttgacact ttgtcagttt ttgatacaat
    39241 agtacaaaat tagaggaggc aggctatgat tcagaaacat gcgattccta ttttagagtt
    39301 tgatgacaat cctcaggcgg ttatcatgcc caatcacgag gggctggact tgcagttgcc
    39361 aaagaagtgt gtttatgcat ttttaggtga ggagattgac cgctatgcaa gggaagtagg
    39421 ggcgaactgt gttggcgaat tcgtttctgc taccaagacc tatccagtct atgttatcaa
    39481 ctacaagggt gaggaggtct gtctggctca ggctcctgtt ggctccgctc cagcagccca
    39541 gtttatggat tggttgattg gctatggtgt ggagcagatt atctctactg ggacctgtgg
    39601 tgtcctagct gatatagagg aaaatgcctt tctagtccct gttcgcgctt tgcgagatga
    39661 gggagccagt taccactatg tggcaccttc tcgttatatg gaaatgcagc cagaggctat
    39721 tgctgctatt gaggaagttt tggaagacag agggattcct tatgaagaag tcatgacctg
    39781 gacgacagac ggtttttacc gagaaacggc tgaaaaggtg gcttatcgta aggaagaagg
    39841 ctgtgctgtt gtggagatgg agtgttctgc tcttgcggca gtagctcaat tgcgtggggt
    39901 tctctggggt gaattgttgt tcacagcaga ttctctagcg gacttggacc agtacgacag
    39961 tcgtgactgg ggctcggaag cttttaataa ggcgctagaa ctgagtttag caagtgttca
    40021 ccacctttag ttgtactggc aaaggatttg ttttatcata aaatgtctag ctcatacttt
    40081 tcaaaaatat gtttaaacga ggtcaccttc ctcttgtcct aggcatgttg aggttgggaa
    40141 aaatctttaa aatcagaaaa acgtatcata tcaggtgata aaaactttga tactatgcgt
    40201 tttatgttgg taagatttag agtgagatga aatgatactc ttcgaaaatc tcttcaaacc
    40261 gcgtcaacgt cgccttgccg tatagatgtt actgacttcg tcagttctat ccacaacctc
    40321 aaaacagtgt tttgagcaac ctgtgactag ctttctaatc gatgccttgg ttctcattgc
    40381 ctataatcaa aaagagaaat tttctcctga aaagcatata gagtagctgg cgttaaaagc
    40441 tcctgtctcg cttttttgac ctatagtcac atctatcaag tattgttctt gcctaagcta
    40501 tcaataaaaa ggtggcattt tttaggcttg gtgttagtag attttgcctt atcctatcta
    40561 agtcatttcg aactttttat ggtacaatgg aaacatgtta ttcaaattat ctaaggaaaa
    40621 aatagagcta ggcttatctc gtttatcgcc agcccgtcgt atttttttga gttttgcctt
    40681 ggtcatttta ctaggctctc ttcttttgag cttgcccttt gtccaagttg aaagctcacg
    40741 agcgacttat tttgatcatc ttttcactgc tgtctctgca gtctgtgtga caggtctctc
    40801 aacccttcca gtagctcaaa cctataatat atggggccaa ataatctgtt tgcttttgat
    40861 tcagatcggt ggtctagggc tcatgacctt tattggggtt ttctatatcc agagcaagca
    40921 aaagcttagt cttcgtagcc gtgcaactat tcaggatagt tttagttatg gagaaactcg
    40981 atctttgaga aagtttgtct attctatttt tctcacgacc tttttggttg agagcttggg
    41041 agctattttg cttagttttc gccttattcc tcaacttggc tggggacgtg gtctttttag
    41101 ttccattttt ctagcgatct cagccttctg taatgccggt tttgataatt tagggagcac
    41161 cagtttattt gcttttcaga ccgatttact ggtcaatctg gtgattgcag gcttgattat
    41221 tacaggcggc cttggtttta tggtctggtt tgatttggct ggtcatgtag gaagaaagaa
    41281 aaaaggacgt ctgcactttc atacgaagct tgtactattg ttgactatag gtttgttgtt
    41341 atttggaacg gcaactactc tctttcttga gtggaacaat gctggaacga ttggcaatct
    41401 ccctgttgcc gataaggttt tagttagctt ttttcaaaca gtgacgatgc gaacagctgg
    41461 cttttctacg atagattata ctcaggctca tcctgtgact cttttgattt atatcttaca
    41521 gatgtttcta ggtggggcac ctggaggaac agctggggga ctcaagatta cgacattttt
    41581 tgtcctcttg gtctttgcac gaagtgagct tctaggcttg cctcatgcca atgttgcgag
    41641 acgaacgatt gcgtcgcgaa cggttcaaaa atcctttagt gtctttatta tctttttgat
    41701 gagcttcttg ataggattga ttctgctagg gataacagcc aaaggcaatc ctccctttat
    41761 ccacctcata tttgaaacca tttcagctct tagtacagtt ggtgtaacgg caaatctgac
    41821 tcctgacctt gggaaattgg ctctcagtgt tatcatgcca cttatgttta tgggacgaat
    41881 tggtcccttg accttgtttg ttagcttggc agattaccat ccagaaaaga aagatatgat
    41941 tcactatatg aaagcagata ttagtattgg ttaagaaagg aaagagcatg tcagatcgta
    42001 cgattggaat tttgggcttg ggaatttttg ggagcagtgt cctagctgcc ctagccaagc
    42061 aggatatgaa tattatcgct attgatgacc acgcagagcg catcaatcag tttgagccag
    42121 ttttggcgcg tggagtgatt ggtgacatca cagatgaaga attattgaga tcagcaggga
    42181 ttgatacctg cgataccgtt gtagtcgcga caggtgaaaa tctggagtcg agtgtgcttg
    42241 cggttatgca ctgtaagagt ttgggggtac cgactgttat tgctaaggtc aaaagtcaga
    42301 ccgctaagaa agtgctagaa aagattggag ctgactcggt tatctcgcca gagtatgaaa
    42361 tggggcagtc tctagcacag accattcttt tccataatag tgttgatgtc tttcagttgg
    42421 ataaaaatgt gtctatcgtg gagatgaaaa ttcctcagtc ttgggcaggt caaagtctga
    42481 gtaaattaga cctccgtggc aaatacaatc tgaatatttt gggtttccga gagcaggaaa
    42541 attccccatt ggatgttgaa tttggaccag atgacctctt gaaagcagat acctatattt
    42601 tggcagtcat caacaaccag tatttggata ccctagtagc attgaattcg taaagaggga
    42661 tgacccctct tttttgatgc ccaagatggc aaatagagac agaagcccct tgtcttctag
    42721 taaaagttct tcaaaggctg gactttatgg taaaatagaa ggaagtgaca agagagagta
    42781 atactcaatg aaaatcaaag atcaaactag gaaactagct gcgggctgct caaaacactg
    42841 ttttgaggtt gtggatagaa ctgacgaagt cagctcaaaa cactgttttg aggttgcaga
    42901 tagaactgac gaagtcagta acatctatac ggcaaggcga cgttgacgcg gtttgaagag
    42961 attttcgaag agtataagaa aaaatcagtc ccctaaagga gcagattatg aagttattgt
    43021 ctatcgccat ttctagctat aatgcagcag cctatcttca ttactgtgtg gagtcgctag
    43081 tgattggtgg tgagcaagtt gggattttga ttatcaatga cgggtctcag gaccagactc
    43141 aggaaatcgc tgagtgttta gctagcaagt atcctaatat cgttagagcc atctatcagg
    43201 aaaataaagg ccatggcggt gtggtcaatc gcggcttggc agaggcttct gggcgctatt
    43261 ttaaagtagt tgacagtgat gactggtgga tcctcgtgcc tacttgaaaa ttcttgaaac
    43321 cttgcaggaa cttgagagca agggtcaaga gatggatgtc tttgtgacca attttgtcta
    43381 tgaaaaggaa ggtcagtctc gtaagaagag tatgagttac gagtcagtct tgcctgttcg
    43441 gcagattttt ggctgggacc aggtcggaaa tttctccaaa ggccagtata tcatgatgca
    43501 ctcgctgatt tatcggacag atttgttgcg tgctagccag ttctaactgc ctgaacatac
    43561 tttttatgtc gataatctct ttgtctttac gccccttcag caggtcaaga ccatgtacta
    43621 tctgcctgtc gatttctatc gttacttgat tgggcgtgag gaccagtctg tcaatgagca
    43681 agtgatgatt aagtgcattg accagcaact caaggtcaat cgactcttgg tagaccagct
    43741 tgatttgtcc caagtgagtc atcccaaaat gcgagaatat ctgctgaatc atattgaaat
    43801 cacgacggtg atttccagta ccctgctcaa ccgatctgaa acagcggagc atctggcaaa
    43861 aaaacgccaa ttgtggacct atattcagca ggaaaatcca gaagtctttc aggctattcg
    43921 taagaccatg ttgagccgtt tgaccaaaca ttctgtcttg ccagatcgca aactgtccaa
    43981 tgtcgtctat caaatcacca aatctgttta tggatttaat taatataagt gttttataag
    44041 agggatttaa gaaaaatttt aactttttct tagtcctttt taatttcagg agattatact
    44101 agagtcatca aataaagaaa gactctaagg agaatcctat gaaattcaat ccaaatcaaa
    44161 gatatactcg ttggtctatt cgccgtctca gtgtcggtgt tgcctcagtt gttgtggcta
    44221 gtggcttctt tgtcctagtt ggtcagccaa gttctgtacg tgccgatgtg gtcaatccga
    44281 ccccaggtca agtcttacct gaagagacat cgggaacgaa agagggtgac ttatcagaaa
    44341 aaccaggaga caccgttctc actcaagcga aacctgaggg cgttactgga aatacgaatt
    44401 cacttccgac acctacagaa agaactgaag tgagcgagga aacaaactct tctagtctgg
    44461 atacactttt tgaaaaagat gaagaagctc aaaaaaatcc agagctaaca gatgtcttaa
    44521 aagaaactgt agatacagct gatgtggatg ggacacaagc aagtccagca gaaactactc
    44581 ctgaacaagt aaaaggtgga gtgaaagaaa atacaaaaga cagcatcgat gttcctgctg
    44641 cttatcttga aaaagctgaa gggaaaggtc ctttcactgc cggtgtaaac caagtaattc
    44701 cttatgaact attcgctggt gatggtatgt taactcgtct attactaaaa gcttcggata
    44761 atgctccttg gtctgacaat ggtactgcta aaaatcctgc tttacctcct cttgaaggat
    44821 taacaaaagg gaaatacttc tatgaagtag acttaaatgg caatactgtt ggtaaacaag
    44881 gtcaagcttt aattgatcaa cttcgagcta atggtactca aacttataaa gctactgtta
    44941 aagtttacgg aaataaagac ggtaaagctg acttgactaa tctagttgct actaaaaatg
    45001 tagacatcaa catcaatgga ttagttgcta aagaaactgt cgaaaaagcc gttgcagaca
    45061 acgttaaaga cagtatcgat gttccagcag cctacctaga aaaagccaag ggtgaaggtc
    45121 cattcacagc aggtgtcaac catgtgattc catacgaact cttcgcaggt gatggcatgt
    45181 tgactcgtct cttgctcaag gcatctgaca aggcaccatg gtcagataac ggcgacgcta
    45241 aaaacccagc tctatctcca ctaggtgaaa acgtgaagac caaaggtcaa tacttctatc
    45301 aattagcctt ggacggaaat gtagctggca aagaaaaaca agcgctcatt gaccagttcc
    45361 gagcaaatgg tactcaaact tacagcgcta cagtcaatgt ctatggtaac aaagatggta
    45421 aaccagactt ggacaacatc gtagcaacta aaaaagtcac tattaacata aacggtttaa
    45481 tttctaaaga aacagttcaa aaagccgttg cagacaacgt taaggacagt atcgatgttc
    45541 cagcagccta cctagaaaag gccaagggtg aaggtccatt cacagcaggt gtcaaccatg
    45601 tgattccata cgaactcttc gcaggtgatg gtatgttgac tcgtctcttg ctcaaggcat
    45661 ctgacaaggc accatggtca gataacggtg acgctaaaaa cccagcccta tctccactag
    45721 gtgaaaacgt gaagaccaaa ggtcaatact tctatcaatt agccttggac ggaaatgtag
    45781 ctggcaaaga aaaacaagcg ctcattgacc agttccgagc aaacggtact caaacttaca
    45841 gcgctacagt caatgtctat ggtaacaaag acggtaaacc agacttggac aacatcgtag
    45901 caactaaaaa agtcactatt aagataaatg ttaaagaaac atcagacaca gcaaatggtt
    45961 cattatcacc ttctaactct ggttctggcg tgactccgat gaatcacaat catgctacag
    46021 gtactacaga tagcatgcct gctgacacca tgacaagttc taccaacacg atggcaggtg
    46081 aaaacatggc tgcttctgct aacaagatgt ctgatacgat gatgtcagag gataaagcta
    46141 tgctaccaaa tactggtgag actcaaacat caatggcaag tattggtttc cttgggcttg
    46201 cgcttgcagg tttactcggt ggtctaggtt tgaaaaacaa aaaagaagaa aactaatcag
    46261 ctaaggaaat aaatgatgga tagtgggctg actaagatta gtttaacaac tcaatcagca
    46321 atcaggactt tctttcaata gcagattaaa atcatcgtaa aacaataaaa atagtgttat
    46381 acttaaagca gtatagcact gtttttatca aaggagagac agatgggaaa gacaatttta
    46441 ctcgttgacg acgaggtaga aatcacagat attcatcaga gatacttaat tcaggcaggt
    46501 tatcaggtct tggtagccca tgatggactg gaagcgctag agctgttcaa gaaaaaaccg
    46561 attgatttga ttatcacaga tgtcatgatg cctcggatgg atggttatga tttaatcagt
    46621 gaggttcaat acttatcacc agagcagcct ttcctattta ttactgctaa gaccagtgaa
    46681 caggacaaga tttacggcct gagcttggga gcagatgatt ttattgctaa gccttttagc
    46741 ccacgtgagc tggttttgcg tgtccacaat attttgcgcc gccttcatcg tgggggcgaa
    46801 acagagctga tttcccttgg caatctaaaa atgaatcata gtagtcatga agttcaaata
    46861 ggagaagaaa tgctggattt aactgttaaa tcatttgaat tgctgtggat tttagctagc
    46921 aatccagagc gagttttctc caagacagac ctctatgaaa agatctggaa agaagactac
    46981 gtggatgaca ccaatacctt gaatgtgcat atccatgctc ttcgacagga gctggcaaaa
    47041 tatagtagtg accaaacgcc cactattaag acagtttggg ggttgggata taagatagag
    47101 aaaccgagag gacaaacatg aaactaaaaa gttatatttt ggttggatat attatttcaa
    47161 ccctcttaac cattttggtt gttttttggg ctgttcaaaa aatgctgatt gcgaaaggcg
    47221 agatttactt tttgcttggg atgaccatcg ttgccagcct tgtcggtgct gggattagtc
    47281 tctttctcct attgccagtc tttacgtcgt tgggcaaact caaggagcat gccaagcggg
    47341 tagcggccaa ggattttcct tcaaatttgg aggttcaagg tcctgtagaa tttcagcaat
    47401 tagggcaaac ttttaatgag atgtcccatg atttgcaggt aagctttgat tccttggaag
    47461 aaagcgaacg agaaaagggc ttgatgattg cccagttgtc gcatgatatt aagactccta
    47521 tcacttcgat ccaagcgacg gtagaaggga ttttggatgg gattatcaag gagtcggagc
    47581 aagctcatta tctagcaacc attggacgcc agacggagag gctcaataaa ctggttgagg
    47641 agttgaattt tttgacccta aacacagcta gaaatcaggt ggaaactacc agtaaagaca
    47701 gtatttttct ggacaagctc ttaattgagt gcatgagtga atttcagttt ttgattgagc
    47761 aggagagaag agatgtccac ttgcaggtaa tcccagagtc tgcccggatt gagggagatt
    47821 atgctaagct ttctcgtatc ttggtgaatc tggtcgataa cgcttttaaa tattctgctc
    47881 caggaaccaa gctggaagtg gtggctaagc tggagaaggg ccagctttca atcagtgtga
    47941 ccgatgaagg gcagggcatt gccccagagg atttggaaaa tattttcaaa cgcctttatc
    48001 gtgtcgaaac ttcgcgtaac atgaagacag gtggtcatgg attaggactt gcgattgcgc
    48061 gtgaattggc ccatcaattg ggtggggaaa tcacagtcag cagccagtac ggtctaggaa
    48121 gtacctttac cctcgttctc aacctctctg gtagtgaaaa taaagcctaa aaccccttta
    48181 caaatccagc tattcatggt agaatagatt ttgtgtgaaa tatcagcagg aaagcatgaa
    48241 gctcgtcaac aggtgtctta tgacaagtaa ccttggctgt ttaggcgaag ggcatctgca
    48301 cgaatcaggg ctttctaagt gactatttcc accgaaatat tatttatatc aggaggacat
    48361 tcatatgtca cgttatacag gaccatcttg gaaacaagct cgtcgccttg gcctttcact
    48421 tacaggtaca ggtaaagaat tggcacgtcg taactacgta ccaggacaac acggaccaaa
    48481 caaccgttct aaattgtcag aatacggttt gcaattggct gaaaaacaaa aacttcgttt
    48541 cacttacggt gtaggtgaaa aacaattccg taacttgttc gtacaagcta caaaaatcaa
    48601 aggcggaatc ctaggtttca actttatgct tcttttggaa cgtcgtttgg ataacgttgt
    48661 ttaccgtctt ggtctcgcga ctactcgtcg tcaagctcgt caattcgtaa accacggtca
    48721 catccttgtt gacgggaaac gcgttgatat cccatcatac cgcgtaactc caggtcaagt
    48781 gatctcagtt cgtgaaaaat cattgaaagt tccagcaatc cttgaagcag tagaagctac
    48841 tcttggacgt ccagcattcg tatcattcga cgctgaaaaa ttggaaggtt cattgactcg
    48901 cttgccagaa cgcgacgaaa tcaacccaga aatcaacgaa gcacttgtcg ttgaattcta
    48961 caacaaaatg ttgtaatatt ttattgaata agataggctt tgaggccttg atattaagca
    49021 ctttgggacg ttctccctta gtgctttttt gatttctctt agtatccagc tataatcgtt
    49081 gagacataac tagaccgata tagtccaaag tgatatagta aaatgaacca aaaatagtac
    49141 acaatgtggt ataatccttt tatggcatat tcaatagatt ttcgtaaaaa agttct
//
LOCUS       DAVKBC010000010        47937 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVKBC010000010 DAVKBC010000000
VERSION     DAVKBC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47937
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.010"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(527..619)
                     /locus_tag="VWX64_000664"
     CDS             complement(527..619)
                     /locus_tag="VWX64_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU9190189.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            780..1751
                     /gene="ruvB"
                     /locus_tag="VWX64_000665"
     CDS             780..1751
                     /gene="ruvB"
                     /locus_tag="VWX64_000665"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU9190190.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            1732..2304
                     /locus_tag="VWX64_000666"
                     /pseudo
     CDS             1732..2304
                     /locus_tag="VWX64_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
     gene            2535..3293
                     /locus_tag="VWX64_000667"
     CDS             2535..3293
                     /locus_tag="VWX64_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU9190191.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            3302..4105
                     /locus_tag="VWX64_000668"
     CDS             3302..4105
                     /locus_tag="VWX64_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU9190192.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFVLTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            4127..5386
                     /gene="rseP"
                     /locus_tag="VWX64_000669"
     CDS             4127..5386
                     /gene="rseP"
                     /locus_tag="VWX64_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU9190193.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            5399..7252
                     /locus_tag="VWX64_000670"
     CDS             5399..7252
                     /locus_tag="VWX64_000670"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU9190194.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            7351..8730
                     /gene="bglA"
                     /locus_tag="VWX64_000671"
     CDS             7351..8730
                     /gene="bglA"
                     /locus_tag="VWX64_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU9190195.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDT
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            8922..10730
                     /gene="glmS"
                     /locus_tag="VWX64_000672"
     CDS             8922..10730
                     /gene="glmS"
                     /locus_tag="VWX64_000672"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU9190196.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGTDNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVVDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLIHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            10849..11898
                     /locus_tag="VWX64_000673"
     CDS             10849..11898
                     /locus_tag="VWX64_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU9190197.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(11998..15795)
                     /gene="spuA"
                     /locus_tag="VWX64_000674"
     CDS             complement(11998..15795)
                     /gene="spuA"
                     /locus_tag="VWX64_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU9190198.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATSKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSNDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRKESVENSSKENISATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            16212..16625
                     /gene="rpsL"
                     /locus_tag="VWX64_000675"
     CDS             16212..16625
                     /gene="rpsL"
                     /locus_tag="VWX64_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU9190199.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16645..17115
                     /gene="rpsG"
                     /locus_tag="VWX64_000676"
     CDS             16645..17115
                     /gene="rpsG"
                     /locus_tag="VWX64_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU9190200.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            17540..19621
                     /gene="fusA"
                     /locus_tag="VWX64_000677"
     CDS             17540..19621
                     /gene="fusA"
                     /locus_tag="VWX64_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU9190201.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            19725..24116
                     /locus_tag="VWX64_000678"
     CDS             19725..24116
                     /locus_tag="VWX64_000678"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU9190202.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQTTEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            24218..24481
                     /locus_tag="VWX64_000679"
     CDS             24218..24481
                     /locus_tag="VWX64_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU9190203.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            24474..24752
                     /locus_tag="VWX64_000680"
     CDS             24474..24752
                     /locus_tag="VWX64_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU9190204.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVCECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            24773..24925
                     /locus_tag="VWX64_000681"
     CDS             24773..24925
                     /locus_tag="VWX64_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190205.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            24947..26188
                     /locus_tag="VWX64_000682"
     CDS             24947..26188
                     /locus_tag="VWX64_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU9190206.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NATSDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVLLFRNGNWAN"
     gene            26198..26428
                     /locus_tag="VWX64_000683"
     CDS             26198..26428
                     /locus_tag="VWX64_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9190207.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            26651..27373
                     /locus_tag="VWX64_000684"
     CDS             26651..27373
                     /locus_tag="VWX64_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9190208.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            27591..28925
                     /gene="pepC"
                     /locus_tag="VWX64_000685"
     CDS             27591..28925
                     /gene="pepC"
                     /locus_tag="VWX64_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU9190209.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAETIVLAPWDPMGALAE"
     gene            complement(28981..29892)
                     /locus_tag="VWX64_000686"
     CDS             complement(28981..29892)
                     /locus_tag="VWX64_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9190210.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(29916..30719)
                     /locus_tag="VWX64_000687"
     CDS             complement(29916..30719)
                     /locus_tag="VWX64_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU9190211.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(30747..31736)
                     /gene="manX"
                     /locus_tag="VWX64_000688"
     CDS             complement(30747..31736)
                     /gene="manX"
                     /locus_tag="VWX64_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU9190212.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVVANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIDISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(31969..32988)
                     /gene="adhP"
                     /locus_tag="VWX64_000689"
     CDS             complement(31969..32988)
                     /gene="adhP"
                     /locus_tag="VWX64_000689"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU9190213.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVARLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(33327..34139)
                     /locus_tag="VWX64_000690"
     CDS             complement(33327..34139)
                     /locus_tag="VWX64_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9190214.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKNPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            34329..35747
                     /locus_tag="VWX64_000691"
     CDS             34329..35747
                     /locus_tag="VWX64_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU9190215.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            35801..36508
                     /locus_tag="VWX64_000692"
     CDS             35801..36508
                     /locus_tag="VWX64_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9190216.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQMSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     SWGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            36602..37576
                     /gene="folP"
                     /locus_tag="VWX64_000693"
     CDS             36602..37576
                     /gene="folP"
                     /locus_tag="VWX64_000693"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU9190217.1"
                     /translation="MMKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLITEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFNQTFTVEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            37578..38900
                     /locus_tag="VWX64_000694"
     CDS             37578..38900
                     /locus_tag="VWX64_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9190218.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLFDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQDSVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNVTDKKEEKQTVRIVTGSLYFLSQVRVYLMERKNENGYTKD"
     gene            38881..39435
                     /gene="folE"
                     /locus_tag="VWX64_000695"
     CDS             38881..39435
                     /gene="folE"
                     /locus_tag="VWX64_000695"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU9190219.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVIIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            39478..40290
                     /gene="folK"
                     /locus_tag="VWX64_000696"
     CDS             39478..40290
                     /gene="folK"
                     /locus_tag="VWX64_000696"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU9190220.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(40335..40652)
                     /locus_tag="VWX64_000697"
     CDS             complement(40335..40652)
                     /locus_tag="VWX64_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU9190221.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     NLF"
     gene            41007..41453
                     /gene="rplM"
                     /locus_tag="VWX64_000698"
     CDS             41007..41453
                     /gene="rplM"
                     /locus_tag="VWX64_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU9190222.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            41472..41864
                     /gene="rpsI"
                     /locus_tag="VWX64_000699"
     CDS             41472..41864
                     /gene="rpsI"
                     /locus_tag="VWX64_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU9190223.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            42255..42593
                     /locus_tag="VWX64_000700"
     CDS             42255..42593
                     /locus_tag="VWX64_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU9190224.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDKHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            42783..44219
                     /locus_tag="VWX64_000701"
     CDS             42783..44219
                     /locus_tag="VWX64_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU9190225.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSLAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAVHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTAQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            44271..44510
                     /locus_tag="VWX64_000702"
     CDS             44271..44510
                     /locus_tag="VWX64_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEU9190226.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGTIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            44640..44954
                     /locus_tag="VWX64_000703"
     CDS             44640..44954
                     /locus_tag="VWX64_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU9190227.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            45072..47051
                     /locus_tag="VWX64_000704"
     CDS             45072..47051
                     /locus_tag="VWX64_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU9190228.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKFGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMVQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEEKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            47061..47375
                     /locus_tag="VWX64_000705"
     CDS             47061..47375
                     /locus_tag="VWX64_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU9190229.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            47406..47912
                     /locus_tag="VWX64_000706"
     CDS             47406..47912
                     /locus_tag="VWX64_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190230.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKVYQQFVQ
                     LEKNSLSL"
BASE COUNT        14004 a         8850 c        10907 g        14176 t
ORIGIN      
        1 tctttttcat aataatctcc cttaactcca cccaatcagg tggagttttt tagctctatt
       61 tcaggctttt ggggactatt ctaaaaataa tttttcgata tttttcggta tttttcggat
      121 tttggtcggg gaattggcgg ggactttttt agcgaatata actaagaaat aggtctgtgg
      181 tcgcttcagc tagttcaaac tcaatttgat tgtaagtgac tgttaattga agaactggaa
      241 ctactgtaat aatgattttg cttgtctagt agtggcgtat taaatgagaa gtgacatgta
      301 agattgtctc ttcgtttacg aaatcaaaat ttctatgaaa ttgatagaat ccctaacgtt
      361 ctcttaatct taaccgtctt gtcgtacagc ggttgaagaa aatgtaaacc tttgacaaaa
      421 ttcgtgaact atgggataat aaaaaggaat tgagtactag ttctatatca taggctagaa
      481 aagaccccaa gctcacgacc aaataagctt gaggtctttt ttgacactat ttgtccttgt
      541 ttagccattt atcgactata cgaagaacga caccgaccac aattggtccg atgatagttt
      601 tgagtactaa ttccatcatg ggctatctca cctcctttcg taggcggtgt agcagtgtcg
      661 tagaatatta taccacataa gtgctaaact taggagtcac ccaatcaggt ggcttttttg
      721 tttgtggctt ggttttttga tataatagag ccatgagtag aattttagat aatgagataa
      781 tgggggatga ggagttagta gaacgcacgc tccgtcctca gtatttacgt gaatatatcg
      841 gacaggataa ggtcaaggac cagctacaaa tctttattga agctgccaaa atgcgggatg
      901 aagcgctgga tcatgtgctc ttatttgggc ctccaggtct cgggaaaacg accatggcct
      961 ttgttattgc caacgaactg ggagtcaatc ttaagcagac gtcgggtcca gtcattgaaa
     1021 aagccggaga tctggtagct attttgaatg agttagagcc tggggatgta ctttttattg
     1081 atgagatcca tcgtttgcca atgtcagtgg aagaggtgct ttatagtgct atggaggact
     1141 tctacataga tattatgatt ggggctggtg agggtagtcg tagtgttcat ttggagttac
     1201 caccttttac cttgattggt gcgacgactc gggctggtat gctctccaat ccgctacggg
     1261 cacgttttgg gattacaggc catatggagt attatgccca tgctgacttg acagaaattg
     1321 tcgagcggac ggcagatatt tttgagatgg aaatcactca tgaggcagca tctgagttgg
     1381 ccctacgtag tcgtgggacc cctcgtattg ccaatcgtct cctcaagcgc gtgcgcgatt
     1441 ttgcccagat aatggggaat ggggtaattg atgatattat taccgataag gctttgacta
     1501 tgctggatgt tgaccatgaa ggtttggact atgtggatca aaaaatcctt cgtaccatga
     1561 ttgagatgta cagtggagga cctgttggtc taggaactct ttctgtgaat atcgccgaag
     1621 agcgtgagac agttgaagat atgtatgagc cttacttgat tcaaaaaggt tttatcatgc
     1681 ggacacggtc tggacgggtg gcgactgcta aggcatatga gcacttaggt tatgaataca
     1741 gtgaaaaata agcaagaaat cttagaggct tttagagaaa atccagatat gatggccatt
     1801 ctgacgatca tccgagacct tggtctgaaa gactcgtggt tggcagcagg ttctgtcaga
     1861 aatttcattt ggaatctttt gtcagacaaa tccccttttg atcatgaaac agatatagat
     1921 gtgattttct ttgatccaga tttttcttat gaggaaacct tattactgga gaaaaagctg
     1981 tgagaggatt ttcctcagta ccagtgggaa ttgaaaaatc aggtctatat gcatcagcac
     2041 agtcctcaca ctgcttccta taccagttct cgtgatgcta tgagtaagta tccagaacgg
     2101 tgtacgacag ttggactgcg cttgaatgaa gaatcagatt ttgaactcta tgcaccttat
     2161 ggtttggagg atattttgaa ttttcaagtt cgtccaactc ctcatttctt agaaaatgaa
     2221 gaccgaatgg aactctatca aacacgttta tccaagaaaa attggcagga gaaatggaaa
     2281 aatttgattt ttaaaaatac ttaaggaaac tttaagctag ggagtgtaca ctaagttcat
     2341 aagttaagaa gaccttaact taaactccta aaactttttc ataataatct ccctataaaa
     2401 ataaagtcgc ccaatcaggc ggcttatttt tttgaaaaat gggcttggtg cctgagaata
     2461 aatagcttag tgatagaaga aaatggggaa atatggtata atgaaacgat agatttttga
     2521 ataggaataa gatcatgttt ggatttttta agaaagataa ggctgtggaa gtagaggttc
     2581 cgacacaggt tcctgctcat atcggcatca tcatggatgg caatggccgt tgggctaaaa
     2641 aacgtatgca accgcgagtt tttggacata aggcgggcat ggaagcattg caaaccgtga
     2701 ccaaggcagc caacaaactg ggcgtcaagg ttattacggt ctatgctttt tctacggaaa
     2761 actggacccg tccagatcag gaagtcaagt ttatcatgaa cttgccagta gagttttatg
     2821 ataattatgt cccggaacta catgcgaata atgttaagat tcaaatgatt ggggagacag
     2881 accgcctgcc taagcaaacc ttcgaagctt taaccaaggc tgaggaattg actaagaaca
     2941 acacaggatt gattcttaat tttgctctta actatggtgg acgtgctgag attacacagg
     3001 cgcttaagtt gatttcccag gatgttttag atgccaaaat caacccaggt gacatcacag
     3061 aggaattgat tggtaactat ctctttaccc agcatttgcc taaggactta cgagacccag
     3121 acttgattat ccgtactagt ggagaattgc gtttgagcaa tttccttcca tggcagggag
     3181 cctatagtga gctttatttt acggacacct tatggcctga ttttgacgaa gcggccttgc
     3241 aggaagctat tcttgcctat aatcgtcgcc atcgccgatt tggaggagtt taggaggaaa
     3301 tatgacccag gatttacaga aaagaacctt gtttgcaggg attgccctgg ctattttcct
     3361 accaatttta atgattgggg gcctcttgct tcagatagca atcggaatca tagccatgct
     3421 agccatgcat gaacttttga agatgagagg tctagagacc atgacgatgg agggcctctt
     3481 gaccctcttt gcaacctttg tattgaccat tcccctggaa aattacctga cttttttgcc
     3541 agttgatggg aatgtggttg cctatagtgt tttgatttca atcatgttag gaacgaccgt
     3601 ttttagcaag tcttatacga ttgaggatgc ggttttccct cttgctatga gcttctacgt
     3661 gggctttgga tttaatgctt tactagatgc tcgtgttgca ggtttggaca aggctctctt
     3721 agccttgtgt atcgtctggg cgacagacag tggtgcctat cttgttggga tgaactatgg
     3781 gaaacgaaag ttagcaccaa gggtatcgcc taataaaacc cttgagggtg ccttgggtgg
     3841 tattttagga gcaattttag taaccattat ctttatgata gttgacagta cagttgctct
     3901 tccatatgga atttacaaga tgtcagtctt tgctattttc tttagcattg ctggacaatt
     3961 tggtgattta ctagaaagtt cgatcaaacg tcattttggt gttaaggatt ctgggaaatt
     4021 tatccctgga catggtggtg ttttggatcg tttcgatagt atgttgcttg tatttccaat
     4081 catgcactta tttggactct tttaatcaaa agacggagga aacgctatgc tcggaatttt
     4141 aacctttatt ctggtttttg ggattattgt agtggtgcac gagttcgggc acttctactt
     4201 tgccaagaaa tcagggattt tagtacgtga atttgccatc ggtatgggac ctaaaatctt
     4261 tgctcacatt ggcaaggatg gaacggccta taccattcga atcttgcctc tgggtggcta
     4321 tgtccgcatg gccggttggg gtgatgatac aactgaaatc aagacaggaa cgcctgttag
     4381 tttgacactt gctgatgatg gtaaggttaa acgcatcaat ctctcaggta aaaaattgga
     4441 tcaaacagcc ctccctatgc aggtgaccca gtttgatttt gaagacaagc tctttatcaa
     4501 aggattggtt ctggaagaag aaaaaacatt tgcagtggat cacgatgcaa cggttgtgga
     4561 agcagatggt actgaggttc ggattgcacc tttagatgtt caatatcaaa atgcgactat
     4621 ctggggcaaa ctgattacca attttgcagg tcctatgaac aattttatct taggtgttgt
     4681 tgttttttgg gttttaatct ttatgcaggg tggtgtcaga gatgttgata ccaatcagtt
     4741 ccatatcatg ccccaaggtg ccttggccaa ggtaggagta ccagaaacgg cacaaattac
     4801 caagattggc tcacatgagg ttagcaactg ggaaagcttg atccaagctg tggaaacaga
     4861 aaccaaagat aagacggcac cgactttgga tgtgactatt tctgaaaagg ggagtgacaa
     4921 acaagtcact gttacacccg aagatagtca aggtcgttac cttctaggtg ttcaaccggg
     4981 ggttaagtca gattttctat ccatgtttgt aggtggtttt acaactgctg ctgactcagc
     5041 tctccgaatt ctctcagctc tgaaaaatct gattttccaa ccggatttga acaagttggg
     5101 tggacctgtt gctatcttta aggcaagtag tgatgctgct aaaaatggaa ttgagaatat
     5161 cttgtacttc ttggcaatga tttccatcaa tattgggatt tttaatctta ttccgattcc
     5221 agccttggat ggtggtaaga ttgtgctcaa tatcctagaa gccatccgcc gcaaaccatt
     5281 gaaacaagaa attgaaacct atgtcacctt ggccggagtg gtcatcatgg ttgtcttgat
     5341 gattgctgtg acttggaatg acattatgcg actctttttt agataatcga ggaatattat
     5401 gaaacaaagt aaaatgccta tcccaacgct tcgcgaaatg ccaagcgatg ctcaagttat
     5461 cagccatgct cttatgttgc gtgctggtta tgttcgccaa gtttcagcag gtgtttattc
     5521 ttatctacca cttgccaacc gtgtgattga aaaagctaaa aacatcatgc gccaagaatt
     5581 cgaaaagatt ggtgctgttg agatgttggc tccagccctt cttagtgcag aattgtggcg
     5641 tgaatcaggt cgttacgaaa cctatggtga agacctttac aaactgaaaa accgtgaaaa
     5701 atcagacttt atcttaggtc caactcacga agaaaccttt acagctattg tccgtgattc
     5761 tgttaaatct tacaagcaat tgccactcaa cctttatcaa attcagccca agtatcgtga
     5821 tgaaaaacgc ccacgtaatg gacttcttcg tacacgtgag tttatcatga aggatgctta
     5881 tagtttccac gctaactatg atagtttgga tagtgtttat gatgagtaca aagcagccta
     5941 tgagcgtatt ttcactcgta gtggtttaga cttcaaggct attattggtg acggtggagc
     6001 catgggtggt aaggatagcc aagaatttat ggccattaca tctgctcgta cagaccttga
     6061 ccgctgggtt gtcttggaca agtcagttgc ctcatttgac gaaattcctg cagaagtgca
     6121 agaagaaatc aaggcagaat tgctcaaatg gatagtctct ggtgaagata ccattgctta
     6181 ctcaagtgag tctagctatg cagctaactt agaaatggca acaaacgagt acaaaccaag
     6241 caaccgtgtt gtcgctgaag aagaagttac tcgtgttgca acgccagatg ttaaatcaat
     6301 tgatgaagtt gcagccttcc tcaatgttcc agaagaacaa acgattaaaa ccctcttcta
     6361 cattgcagat ggtgagcttg ttgcagccct tctagttgga aatgaccaac tcaacgaagt
     6421 caagttgaaa aaccacttag gagcagattt ctttgacgtt gctagcgaag aagaagtggc
     6481 gaatgttgtt caagcaggat ttggttcact tggaccagtt ggtttgccag agaatattaa
     6541 aattattgca gatcgtaagg tgcaagatgt tcgcaatgca gttgtcggtg ctaacgaaga
     6601 tggctaccac ttgactggtg tgaacccagg ccgtgatttt actgcagaat atgtggatat
     6661 ccgtgaagtt cgtgagggtg aaatttcccc agatggacaa ggtgtcctta actttgcgcg
     6721 tggtattgag atcggtcata ttttcaaact cggaactcgc tactcagcaa gcatgggagc
     6781 agatgtcttg gatgaaaatg gtcgtgctgt gccaatcatc atgggatgtt acggtatcgg
     6841 tgtcagccgt cttctttcag cagtgatgga gcaacacgct cgcctctttg ttaacaaaac
     6901 gccaaaaggt gaataccgtt acgcttgggg aatcaatttc cctaaagaat tggcaccatt
     6961 tgatgtgcat ttgattactg tcaatgtcaa ggatgaagaa gcgcaagcct tgacagaaaa
     7021 acttgaagca agcttgatgg gagctggtta tgaagtcttg acagatgacc gtaacgaacg
     7081 tgtcggtgtt aaatttagcg atagtgactt gattggtctt ccaatccgta tcactgttgg
     7141 taaaaaagcg gccgatggca ttgtagaagt taagatcaag gcaactggtg acaccattga
     7201 ggttcatgca gataacgtgc ttgaaacgct tgaaatccta agcaagaaat aaaaactata
     7261 atcagaagaa aaacaaggaa aaaatgtaac tagtttttac cttgtttttt ctgtataatg
     7321 ggagaaatga gtagataaag aggtaaatgt atgctaagat ttccaaagga ttttgtctgg
     7381 ggatcctcta cttctggacc gcagacagaa ggacgtgtag ctggtgacgg taagggagac
     7441 aatctctggg attactggtt ccaagtggag ccaaatcgtt actataatgg gattggttca
     7501 gataagacat cgacttttta tgaaaattgg gagcgggata ttgagctttt gttagagact
     7561 ggtcacacag cctttcggac ttctattcag tggtcacgga tttttccaca aggctgtgga
     7621 aaagtcaaca ctcaaggtgt ggatttttat cgtaaggtct ttgaggctat taaggctaaa
     7681 ggaattcgtc tgttagtcaa tctctatcat tttgatttac cttttgccct tcaagaggat
     7741 ggtgatggtt gggaaaataa ggcgacagtc tcagcctatg aagactatgc tcgtttttgt
     7801 tttgagactt atggagattt agtggatcaa tggattacct ttaacgagcc catcgttcct
     7861 gtagaatttg gttattttta tgatgcccat tatccacata aggtggatgc agaggcagct
     7921 gttaaggtag cctatcatac acaattggcc agcagccggg ctgttaaggc ttgccatgaa
     7981 cttttgcctg attccaagat tgggattgtc ctcaacttga caccggctta tccacgtagc
     8041 cagcatcctg ctgatgtcaa ggcagctcgt attgcggccc tttttcaggc ccaatctttc
     8101 ttagatccat ctgtcttggg gacttatcca caggagttgg tagaaatctt gcatgaacac
     8161 ggtcttttac ctgatactac agaggaagag ttggaactca ttcgtgataa tacggtggac
     8221 ttccttggtg tgaactacta tcaacctttg cgtgttatgg ctcctcgatt tgctaagcat
     8281 ccagatagtc cactcttacc agaacatttt tacgagcctt atgtgatgcc tggacgtaaa
     8341 atcaattctc accgtggttg ggagatttat gagcaaggga tttatgacat cgcccaaaat
     8401 atcaaggaaa attatggcaa tattgagtgg atgttgactg agaatggtat gggtgttgaa
     8461 ggggaagaaa aattccgtca agatggaatg attcaagatg attaccgtat tgactttgta
     8521 aaaggtcatc ttcgtgaact tcaccgtgcc attgaagatg gtgccaactg taagggctac
     8581 ttgatttgga cctttattga ctgctggtca tggctcaaca gctataaaaa tcgctatggt
     8641 ttggtcgaat tagacttgga aacgcaagaa cgtcgtctga agaaatcagg ccactggttc
     8701 aaagaattaa gcgataataa tggattttaa aaaggactct gactgattat cccaatcggt
     8761 cagagttttt tgcttacagg agcttaattt gaactatacc aatttttact cttgacaagt
     8821 gaaagaaaca agtatatact gtttttgctg attctataaa agatgaatta gactatacca
     8881 attttaagga gaaagcacag cttgcctgtg tcgtatatac tatgtgtgga attgttggtg
     8941 ttgttggaaa cacaaatgca actgatattt tgattcaagg gcttgaaaag cttgaatacc
     9001 gtggctatga ttctgcggga atttttgtcc tagatggtac tgataaccat ttggtgaagg
     9061 ctgttggtcg tatcgcagaa ttgtctgcta agacagctgg tgttgaggga acaactggta
     9121 tcggacatac tcgttgggca actcatggga aaccaacgga agacaatgct cacccacacc
     9181 gctctgagac agaacgtttt gtcttggttc acaatggggt gattgaaaac taccttgaaa
     9241 ttaaagaaga ataccttgct gggcaccact tcaaagggca aacagatacg gaaatcgccg
     9301 tacatttgat tggaaaattt gcggaagaag acggtctctc agttcttgaa gcctttaaaa
     9361 aagctcttca tattatccgt ggttcatatg cctttgcctt gattgactct gaaaatccag
     9421 atgtcatcta tgtagcgaaa aacaaatctc cacttttgat tggtcttggg gaaggctaca
     9481 atatggtctg ctcagatgct atggctatga ttcgtgaaac caaccaatac atggaaattc
     9541 atgaccaaga gttggtaatc gtcaaggctg atagcgtgga agttcaagac tatgatggta
     9601 acagtcgtga acgtgctagc tatactgcgg aacttgactt gtcagatatc ggtaagggaa
     9661 cttatcctta ctacatgctt aaggaaattg atgagcaacc aactgttatg cgtaaactca
     9721 ttcaagccta cacggatgat gctggtcaag tagtggttga tcctgctatc attaaggctg
     9781 ttcaagacgc agaccgcatc tacatccttg cagctggaac atcttaccat gcaggatttg
     9841 cttctaagaa aatgttggaa gaattgacag atacaccagt tgaacttggc atctcatctg
     9901 agtggggcta cggtatgcca cttctcagca agaaaccact cttcatcttt atcagccaat
     9961 ctggtgaaac agcggatagt cgtcaagttt tggtcaaggc taatgaaatg ggaattccaa
    10021 gcttaacagt gacaaatgtt ccaggctcaa ccctctcacg tgaagccaac tataccatgc
    10081 tccttcacgc aggtcctgaa attgccgtgg catcaactaa agcctataca gcgcaaatcg
    10141 cagcccttgc cttccttgca aaagcagtcg gagaagcaaa tggtaatgct aaagcgcaag
    10201 cctttgacct gattcatgaa ttgtcaatcg tagctcagtc tatcgaatca actctttcag
    10261 agaaagaaac cattgaagcc aaggttcgtg aacttcttga aacaactcgt aacgcctttt
    10321 acatcggacg tggtcaagat tactacgtag ccatggaagc aagtctcaaa ctcaaagaga
    10381 tttcttatat ccagtgtgaa ggctttgctg caggagaact caagcacgga accattgcct
    10441 tgattgaaga aggaacgcct gttttggctc tcttgtcaga tccagttctt gccaatcata
    10501 ctcgtggaaa tatccaagag gtcgcagccc gtggtgccaa agtcctcact atcgcagaag
    10561 agaatgtagc caaagatacc gacgatatcg tccttacgac cgtacatcca tacctctcac
    10621 caatttcaat ggtcgtacca acgcaattag tcgcttactt tgcaaccctc caccgtggcc
    10681 tcgatgtgga caaaccacgt aaccttgcca agtcagtaac ggtagaataa gctaaaaaag
    10741 tctagttatc taggcttttt cttgtgagca aattggttgc ttgtactcaa gattcgtgtt
    10801 agaataattt ttcaaattga aggacagaga tagacaagga gaatcacaat ggtagaattg
    10861 ggaatttcaa catttgggga aataacggag cttgaaggga ctggacaaac ttacagtcat
    10921 gctgaacgca ttcgccagtt ggtggcagag attgagctgg ctgacaaggt tggtttggac
    10981 gtatatggga ttggcgagca ccatcgggcg gattttgcag tatcagcccc agagattgtc
    11041 ctggccgctg gggcagtcaa taccaagaaa atccgtttga ccagtgcagt cagcattctg
    11101 tcaagcatgg acccgattcg tttgttccaa cagtatgcca ctatcgatgc tttgtcaaat
    11161 ggacgatcgg agattatggc tggaaggggc tctttcacgg aatctttccc tctgtttggt
    11221 tatgacttga aagactacga ctctcttttt gatgagaaat tagacttgct tcagttagtc
    11281 aatgaaaaga ccaagttaga ctggcaaggt cgattgactc aaacgattgc tggtaaagaa
    11341 gtttatcctc gtccagttca ggacaaattg cccttgtgga tagctacagg tggtcatgtc
    11401 gaatcaacag tgaagattgc tcaggctggt ctaccgattg tatatgctat tattggtggt
    11461 aatccacgtt attttaaaaa gttgattcag gcttatcgtg agattggaag cgaagcgggc
    11521 catgctgaca aagacttgaa agtgggagcc cattcttggg ggtggattgc ggaagatggt
    11581 gagcaggcgg tgaaagatta tttccatccg actaagcaag tggtggatgc tatttccaaa
    11641 gaccgtccgc actggcagga attgcgttat gagcaatatt tggagcaggt agggtcaaat
    11701 ggcgccatgt ttgttggcaa tccagatcag gtggccgaaa aattgattcg catgatagag
    11761 gatttaggat tggaccgctt catgcttcat ctaccgcttg gttctatgcc tcatgaccag
    11821 gttctgagag ctattgaact cttcggaaca caagttgcac ccaaagtacg agcttatttt
    11881 gctatgaaag aggcttaata aaaaatccta atcaagttta ttaggacaac aaatattgta
    11941 cgaaaattaa tcccccgagc tataatgctt gggggatttt tctataggag ggctagctta
    12001 gttctctttt ttatttttta gtaagaaacc gagaccaagg agcgcaagga ggctgattcc
    12061 tgcaaatagg agtttgtttt cgtttttgat tcctgtattt ggaagttcag cttgtctatc
    12121 tggggttgca gatatatttt ccttgctaga gttttctacc gattcttttc gaaccgcttc
    12181 ttttacagat gatgcttgtg cttcttgtgc tggttgttca gcttgtgaat cagctgtagc
    12241 ttggctaggt ttattttccg catcagctac tttggcatct ggtttagtag aatcaggtct
    12301 agcttctgga gctgggtctt gatgtgcagg gtgagaagct tcattttgat gttcaggctt
    12361 ggaaggggtt gagtctggtt tctcttctgc agttgactca tggctagttc cattttgaga
    12421 gactcgaaga acagtagctg taagggcatt caattttaag cctttttcag tccattcaag
    12481 tcctttcggg ttggcaattc cgactgatcc tgcttggttt tcatctgcca aaacttccgc
    12541 atttcttaga tgtgcaaagg cagttcccaa attaaattcg cgagcttttt catccgcatt
    12601 gacaaagact gcgtagatat cgccgtttgg agcagtgatt tggtagccaa tcactacatc
    12661 ctctttttcc acaccatttt ggcctgggac agtgatgagg tggacacggt ctttgatatc
    12721 ttggagactc ttaagtcgga aggcatctgt agattgacga agggcaatca aacctttcat
    12781 atagtcacgg ctcttgacat tttcaggata agctttacca tctgtagcct tagtccagtc
    12841 aaacttgttg actgcgtcgc tagaatcgta agaatcatgg atgaagtaag gatagtcaaa
    12901 tgggttgccg tccttatcac gcaacaagtg agatttgttt ggaaccttat cctctgctac
    12961 tggagtcttg taggctgggt cacggaattg tttagtacgt ccatattcct gaccggagtg
    13021 gataaatgga gttccttgag ctgtcaagac catgagattt ccaagtcgta aacgacggtg
    13081 gatttcagca tagttctcag ccttgcttgg gtcttttttg atagactggg caatgatgtc
    13141 aaagagggtc aagttatcat gggctgcgat gtattggatg acatctccag ggctgtcagc
    13201 ttcaaagtta gttggttgag caatgagatt tttaaagatg gtgttgacat cacgcttgcc
    13261 acctgtgata aaggcaggtt gaccttcgtt tggataacca gatttgaggt tgttacggat
    13321 gtcatctgaa aagacagcga cagtatcggt atgtttcatc caatcttggt cagcagcttt
    13381 agtaggcatg ttttcatcac cggcataggt tctccaacct tcgcctaaca tgattagatt
    13441 tggattgagg gcgcgtgcag ccttgtaagc ttcttcgata gaagcggcgt catggtctcc
    13501 catcatatcg aagcggaagc catccacttt gtaggtatca actaggtatt tgatagagtc
    13561 aactaggagg cgtttggtca tatggtgggt tgtccccaag cgtccaccac caaagctagt
    13621 tcgaggtgtg ccatcggcat ccataaagtg gtagtagttt ggctctaggt cttcaaagat
    13681 atcgactttg gctgtgtggt tataaacgac atctaggata gctcccatac cacgtttgtg
    13741 gatttcgttg atgaggtttt taaattctgc gattcgtttt tctggattct taggatcgct
    13801 tgagtacata ccagtcaagg agaagtagtt ttgagggtca tatccccagt tgtagttgct
    13861 gttgcttgaa gcatagtcag acaagcgttc atggtttttc aattcattga caaagtagta
    13921 agacaagact ggaaggagct ggatatgggt tacacccaag tctttgagat agtctagttt
    13981 ttcaatgaag gcttcaaaag tcccaaatgg tttggtcaag tcttttgcaa tggcaggatc
    14041 tgaagtgaag tcacgcacat gagcttcgta gataacggcg tcttcacgag tcttgaaatt
    14101 gtgaatctta ccataagtca agtcttgagg tccgagttta gctggatcta caaaggcggc
    14161 tttagccact ttatgggcat cgtcaatctt ggcatcgttg ctattccaag cagcaagaga
    14221 tttagcgtaa ggatcgagtg caagaacagt tttaccttga cgctcgattt ggtattgata
    14281 atagtagcca gtgaaatctg tgattccgag tttgtttgtg ctgtctagag tttgtttcca
    14341 agttcctctt tccccttttt cgagagcgac agttccaact actttgtcag ggtcattctt
    14401 gtcgtagaca acaacagaaa ccttatcagc acttggtgac caaagggtca aatcaacttg
    14461 ttttccttct tcttttaggt cagctcctag tttgccatca tagctgtatg tctcatcttt
    14521 caggcgccag cttgttttgg tagtgaattg gtcggaattg tagctaacag tataaggatg
    14581 ttttgtgtca gagaaatctc cgctgtaggt cactttctta ccagcttcat cgattgcaac
    14641 atcggtaata gttaccttgt ttcctaggtg attagtgatg ttggagtgtt tgaggatatc
    14701 ttctttttta gcaccgacaa gtgttgaaaa gctactttca atgctagaag tgcctacgtg
    14761 ttgggctcct gtcatacgga tatcatggac atagtatgga tttgtgtaaa tcgattcatc
    14821 atcgtctttt aggaaaattt ggctatgatt tttcaaatct gtgaacttat aattttcttt
    14881 acggattttc acgtcgtctc cttgtttgct ctcatctagt aataaaaatc caaattctct
    14941 tgcggcttca ttaagaggaa tgtcgatata gcggccatat ttgcttgtag ccgtaaagtc
    15001 tgttccgtca ggccattgag cgctacttgg attttttaca tctccccagt accagagaga
    15061 tttcttgtca tagttgccat ctgtgcggta gtagttgacg cgaacagttc ctgcaggctg
    15121 tggctcgtaa gagaaaacct tgtaatcttg gtctaaccaa gcctcgttca tttttggaac
    15181 tagtttttct acagatttat cgccggttag attttttcca gctgtattgt tgatgaggaa
    15241 gctaattttc ttggcttgtt ctccctttaa tttgacatct aggtaatagc cgtagtcatc
    15301 tttcttggca tccttgaagg acaaagctcc gtttggccag ttttcagatg gtttttcaac
    15361 atcgtcccaa gtccatagtc cttgagcatc cttgttttct tcaggaagtt ttttgacatg
    15421 gatacggaag tagttatctt cgatgggctc ttctgcctta gtttcagttg ttactggact
    15481 agtagaagta gttggctctg ttgcaggttt ttcttctgtt ttctctaggg aagcgtttgc
    15541 atttctaggt gaagaaatat cactttcgtt cttaccagag ccagctgctg tatcagtaag
    15601 aggttgggca agggtggttg tatttctgtt gttgggttcg ttagtggttg gtgtactttc
    15661 gtcggatgag atagttggtg tagccatggc aagcaagaca aggcttgcgc cgataaggac
    15721 agaaccagtc ccatttttga gggaacggat gctgtagacc atttttttct cagtgtgaga
    15781 tggtgttttt ctcataatga ttctccaatc aataaatttc tatatcagta tagcatgtag
    15841 taaaacaata tgcaagcgtt ttctttgatt tgtgaaaaaa attcttactt ttgagaagtt
    15901 ttctgtacta ttttatatat cagtataaat gacggagata aaaatgtcac ataagccaag
    15961 ccgtattatt aggaagatga tgtgttccca gctattttta ttcagaaatt gatctctaac
    16021 attaccaata aaaaagaaaa atatcttgac aaacaaggga aaattttgtt acaataatag
    16081 acggtacttt ttacttttgg tctctcaaga gtgtacaggg acgtgctgac aaatgttgca
    16141 aaagtacaca cagatgatat ctgtcaccaa gtgtatcatc accaaaaata aaaaaacaca
    16201 ggagaatgta gatgcctaca attaaccaat tggttcgcaa accgcgtaaa tcaaaagtag
    16261 aaaaatctaa atcaccagct ttgaacgttg gttacaatag tcataaaaaa gttcaaacaa
    16321 acgtttcttc accacaaaaa cgtggtgttg caactcgtgt tggaacaatg acacctaaaa
    16381 aacctaactc agcccttcgt aaattcgctc gtgtacgttt gagcaacctt atcgaagtta
    16441 ctgcctacat cccaggtatc ggacacaact tgcaagagca cagcgtggtg cttcttcgcg
    16501 gtggacgtgt aaaagacctt ccaggggtac gttaccatat cgtccgtggt gcacttgata
    16561 ctgcaggtgt taacgatcgt aaacaaggtc gttctaaata cggtactaaa cgtccaaaag
    16621 cataaggaaa ggggataaag agaaatgagt cgtaaaaata gagctccaaa acgtgacgta
    16681 ttgccagatc cgctatacaa ttcacaacta gttactcgtc ttatcaaccg cgttatgctt
    16741 gatggtaaac gtggtactgc tgcttcaatc gtttacggtg cttttgagca aatcaaagaa
    16801 gctactggca acgatgcact tgaagtattt gaaacagcta tggaaaacat catgcctgta
    16861 cttgaagtac gtgcacgtcg tgttggtggt tctaactacc aagtcccagt tgaagttcgt
    16921 ccagaacgtc gtacaacact tggacttcgt tggttggtaa caatcgctcg tcttcgtggt
    16981 gaacacacaa tgcaagaccg tcttgcaaaa gaaatcttgg atgctgctaa caacactggt
    17041 gcagcagtta agaaacgtga agatactcac cgtatggctg aagctaaccg tgcattcgca
    17101 cacttccgtt ggtaagatag gatgcgaaag cgttaagaaa gttccagaga aaatagggaa
    17161 tcgaagcagg ttgcggttgc aaccaatgag attcatcttt ttctccagac ttttagcttg
    17221 agctcaacta aatcatgatg ttaggaacgg taaggatgca aggtgaaaat aggaaactga
    17281 cgcagtattc gacgaataca aggagtttta tctttttcac gcagcatccc gttccagctc
    17341 acatcggcta actaacttta gcccgggttc aaattagcta aatcgattag tattagctat
    17401 aactcagctt accatctcgt aagttgaaac caacaatagc atgaaaacat tgagaacggg
    17461 taggtcctgc ctatccgttt ttattaaaat cgtgttataa tagaatagaa atcaaaaata
    17521 aataggagaa acaaacctca tggcacgcga attttcactt gaaaaaactc gtaatatcgg
    17581 tatcatggct cacgtcgatg ccggtaaaac aacaactact gagcgtattc tttactacac
    17641 tggtaaaatc cacaaaatcg gtgaaactca cgaaggtgcg tcacaaatgg actggatgga
    17701 gcaagagcaa gaacgtggta tcacgatcac atctgctgcg acaacagctc aatggaacaa
    17761 ccaccgcgta aacatcatcg acacaccagg acacgtggac ttcacaatcg aagtacaacg
    17821 ttctcttcgt gtattggatg gtgcggttac cgttcttgac tcacaatcag gtgttgagcc
    17881 tcaaactgaa acagtttggc gtcaagcaac tgagtacgga gttccacgta tcgtatttgc
    17941 caacaaaatg gacaaaatcg gtgctgactt cctttactct gtaagcacac ttcacgatcg
    18001 tcttcaagca aatgcacacc caatccaatt gccaatcggt tctgaagatg acttccgtgg
    18061 tatcattgac ttgatcaaga tgaaagctga aatctatact aacgaccttg gtacggatat
    18121 ccttgaagaa gacatcccag ctgaatacct tgaccaagct caagaatacc gtgaaaaatt
    18181 gattgaagca gttgctgaaa ctgacgaaga attgatgatg aaatacctcg aaggtgaaga
    18241 aatcactaac gaagaattga aagctggtat ccgtaaagcg actatcaacg ttgaattctt
    18301 cccagtattg tgtggttcag ccttcaaaaa caaaggtgtt caattgatgc ttgatgcggt
    18361 tatcgactac cttccaagcc cacttgacat cccagcaatc aaaggtatta acccagatac
    18421 agacgctgaa gaaattcgtc cagcatctga cgaagagcca tttgcagctc ttgccttcaa
    18481 gatcatgact gacccattcg taggtcgttt gacattcttc cgtgtttact caggtgttct
    18541 tcaatcaggt tcatacgtat tgaatacttc taaaggtaaa cgtgaacgta tcggacgtat
    18601 ccttcaaatg cacgctaaca gccgtcaaga aatcgacact gtttactcag gtgatatcgc
    18661 tgctgccgtt ggtttgaaag atactacaac tggtgactca ttgacagatg aaaaagctaa
    18721 aatcatcctt gagtcaatca acgttccaga accagttatc caattgatgg ttgagccaaa
    18781 atctaaagct gaccaagaca agatgggtat cgcccttcaa aaattggctg aagaagatcc
    18841 aacattccgc gttgaaacaa acgttgaaac tggtgaaaca gttatctcag gtatgggtga
    18901 acttcacctt gacgtccttg ttgatcgtat gcgtcgtgag ttcaaagttg aagcgaacgt
    18961 aggtgctcct caagtatctt accgtgaaac attccgcgct tctactcaag cacgtggatt
    19021 cttcaaacgt cagtctggtg gtaaaggtca attcggtgat gtatggattg aatttactcc
    19081 aaacgaagaa ggtaaaggat tcgaattcga aaacgcaatc gtcggtggtg tggttcctcg
    19141 tgaatttatc ccagcggttg aaaaaggttt ggtagaatct atggctaacg gtgttcttgc
    19201 aggttaccca atggttgacg ttaaagctaa gctttatgat ggttcatatc acgatgtcga
    19261 ctcatctgaa actgccttca agattgcggc ttcactttcc cttaaagaag ctgctaaatc
    19321 agcacaacca gctatccttg aaccaatgat gcttgtaaca atcactgttc cagaagaaaa
    19381 ccttggtgat gttatgggtc acgtaactgc tcgtcgtgga cgtgtagatg gtatggaagc
    19441 acacggtaac agccaaatcg ttcgtgctta cgttccactt gctgaaatgt tcggttacgc
    19501 aacagttctt cgttctgcat ctcaaggacg tggtacattc atgatggtat ttgaccacta
    19561 cgaagatgta cctaagtcag tacaagaaga aattattaag aaaaataaag gtgaagacta
    19621 atccgtcctc actctagaag gaagtcactt agtggcttcc ttttgtcttt agaaaatacc
    19681 tctaaatatg gtaaaatagt agaagaataa tgtgaggaaa atgaatgtca aatagttttg
    19741 aaattttgat gaatcaattg gggatgcctg ctgaaatgag acaggctcct gctttagcac
    19801 aggctaatat tgagcgagtt gtggttcata aaattagtaa ggtatgggag tttcatttcg
    19861 tattttctaa tattttaccg attgaaatct ttttagaatt aaagaaaggt ttgagcgaag
    19921 aattttctaa gacaggcaat aaagctgttt ttgaaattaa ggctcggtct caagaatttt
    19981 caaatcagct cttgcagtcc tactataggg aggctttctc tgaaggtcca tgtgctagtc
    20041 aaggttttaa gtccctttat caaaatttgc aagttcgtgc tgagggcaat cagctattta
    20101 ttgaaggatc tgaagcgatt gataaggaac attttaagaa gaatcatctt cctaatttag
    20161 ccaaacaact tgaaaagttt ggttttccaa cttttaactg tcaagtagag aagaatgatg
    20221 tcctgaccca agagcaggaa gaggcctttc atgctgaaaa tgagcagatt gttcaagctg
    20281 ccaatgagga agcgctccgt gctatggaac aactggagca gatggcacct cctccagcgg
    20341 aagagaaacc agtctttgat tttcaagcga aaaaagctgc agctaaaccc aagctggata
    20401 aggcggagat tactcctatg atcgaagtga cgacagagga aaatcgtctg gtctttgaag
    20461 gggttgtttt tgatgtggag caaaaagtga ctagaacagg tcgtgtttta atcaacttta
    20521 aaatgacgga ctacacttca agtttttcta tgcaaaagtg ggttaaaaac gaggaagagg
    20581 cccagaagtt tgacctcatc aagaagaatt cttggctccg agttcgaggg aatgtggaga
    20641 tgaataactt cacacgcgat ttgactatga acgtacagga tgtgcaggaa gttgttcact
    20701 atgagcggaa ggatttgatg ccagaaggtg agcgtcgggt tgagtttcat gctcatacta
    20761 acatgtcgac tatggatgct ttgccagagg tcgaagagat tgttgcaaca gctgctaagt
    20821 ggggacacaa ggcggttgct attacggacc atgggaatgt ccagtccttt ccacatggct
    20881 ataaggcggc taagaaagcg ggaatccagc tgatctatgg gatggaagcc aatatcgtgg
    20941 aggaccgtgt ccctatcgtc tataacgaag tggagatgga cttgtcagaa gcaacctacg
    21001 tggtctttga cgtggaaacg acgggacttt cagctatcta taatgacttg attcaggttg
    21061 cggcctctaa gatgtacaag gggaatgtta ttgctgaatt tgatgaattt atcaatcctg
    21121 ggcatccctt gtcagccttt actacagagt taactggaat tacagatgat catgtcaaaa
    21181 atgccaaacc actagaacaa gttttgcaag aattccaaga attttgcaag gatacggtcc
    21241 tagttgccca caatgctacc tttgacgttg gctttatgaa tgctaattat gagcgtcatg
    21301 gtcttccaaa gattagtcag ccagttattg atacgctgga gtttgctaga aacctctatc
    21361 ctgagtataa acgccatggt ttggggcctt tgaccaagcg ttttggtgtg gccttggaac
    21421 atcaccacat ggccaactac gatgcggaag cgactggtcg tctgcttttc atctttatca
    21481 aagaggtagc agaaaaacat ggtgtgaccg atttagctag actcaacatt gatctaatca
    21541 gtccagattc ttacaaaaaa gctcggatca agcatgcgac catctatgtc aagaatcagg
    21601 taggtctaaa aaatatcttt aagctggttt ccttgtctaa taccaagtat tttgaaggag
    21661 tgccacggat tccgagaacg gttctagatg cccatcgaga gggcttgatt ttaggttcag
    21721 cctgttcaga gggtgaagtt tttgacgtgg tcgtttctca aggtgtggat gcggcggttg
    21781 aggtggccaa gtattatgac tttatcgagg tcatgccacc ggctatctat gcgcccttga
    21841 ttgccaaaga gcaggtcaag gatatggagg aactccagac cattatcaag agtttgatag
    21901 aggttggaga tcgccttggc aagcctgttc tggctacggg aaatgttcac tatatcgaac
    21961 cggaagaaga gatttatcgt gaaattatcg tccgtagttt gggacagggt gcgatgatta
    22021 accgaactat cggtcatggt gaacatgccc aaccagcgcc acttccaaag gctcattttc
    22081 gaacgactaa tgagatgttg gatgaatttg cctttttggg agaggaactg gctcgtaaac
    22141 tggttattga aaacactaat gccttggcag aaatatttga acccgttgaa gtcgttaagg
    22201 gtgacttgta tacgcctttc atcgacaagg ctgaagaaac agttgctgag ttgacctata
    22261 agaaagcttt tgagatttat ggaaatccgc tgccagatat tgttgatttg cggattgaaa
    22321 aagaattaac atccatactg gggaatggat ttgctgtgat ttatctggca tcgcagatgc
    22381 tggtgcaacg ttctaatgaa cggggttatt tggttggttc tcgtgggtct gtcggatcta
    22441 gtttcgttgc gaccatgatt gggattacgg aggtcaatcc tctctctcct cactatgtct
    22501 gtggtcagtg tcagtacagt gagtttatca cagatggttc gtacggttca ggatttgata
    22561 tgccccataa ggactgtcca aactgtggtc acaaactcag taaaaacgga caggatattc
    22621 cgtttgagac cttccttggt tttgatgggg ataaggttcc tgatattgac ttgaacttct
    22681 cgggagaaga tcagcctagc gcccacttgg atgtgcgtga tatctttggt gaagaatatg
    22741 ccttccgtgc gggaacggtt ggtacggtag ctgccaagac tgcctatgga tttgtcaagg
    22801 gttacgagcg agattatggc aagttttatc gtgatgcaga agtagaacgc ctcgctcaag
    22861 gagcggcggg tgtcaagcgg acaacaggcc aacacccggg gggaatcgtt gttattccga
    22921 actacatgga tgtctacgat tttacgcctg tccagtatcc agcagatgat gtcacggctg
    22981 aatggcagac cactcacttt aacttccacg atatcgatga gaacgtcctc aaactcgatg
    23041 tactgggaca tgatgatccg accatgattc gaaaacttca ggatttgtct ggtattgacc
    23101 ctaataaaat tcctatggat gacgaaggcg tgatggcact cttttctggg actgatgtgc
    23161 taggggtaac acctgaacaa attggaacgc ctacgggtat gttggggatt ccagagtttg
    23221 gaacaaattt cgtacgtgga atggtagacg aaacccatcc gacaaccttt gcggaattgc
    23281 ttcagctgtc tggtctgtcc cacggtactg acgtttggtt ggggaatgct caggatctga
    23341 ttaagcaagg aatagcggac ctatcgactg ttatcggttg tcgggacgac atcatggttt
    23401 acctcatgca tgcgggtctg gaacctaaga tggcctttac cattatggaa cgggtacgta
    23461 agggtttgtg gctaaagatt tcagaagagg agagaaatga ctatatcgaa gccatgaagg
    23521 ctaataaggt gccagagtgg tatatcgaat cctgtgggaa aattaagtac atgttcccta
    23581 aggcccatgc ggcagcctac gttatgatgg ccttgcgtgt agcttacttc aaggttcacc
    23641 atcctattta ttactactgt gcttacttct ccattcgtgc taaggctttt gatatcaaga
    23701 ccatgggtgc gggcttggag gtcatcaagc gcagaatgga agaaatctct gaaaaacgga
    23761 agaacaatga agcctctaat gtggaaatcg atctctatac aactcttgag attgtcaatg
    23821 agatgtggga acgaggtttc aagtttggta aattagatct ctactgtagt cagacgacag
    23881 agttcctcat cgacggggat acccttatcc caccatttgt agcaatggat ggtctggggg
    23941 agaacgttgc caagcaactg gtgcgggcgc gtgaagaggg agaattcctc tctaaaacag
    24001 aactacgcaa gcgtggtgga ctctcatcaa ccttggttga aaagatggat gagatgggta
    24061 ttcttggaaa tatgccagag gataaccagt tgagtttgtt tgatgagttg ttttaaaaaa
    24121 ttgcttaata atctattaaa agaggctaac gtatatccaa tagatttaca ttagctttct
    24181 tttttgttaa aatagtctat ggaaagaggg tgagagtatg tcaaagatga gtataagcat
    24241 ccgtctggat agtgaggtta aggagcaggc ccaacaggtg tttagtaatc tgggaatgga
    24301 tatgacaaca gctattaata ttttccttcg tcaggcaatt caatatcagg gattaccttt
    24361 tgatgttaga ctagacgaaa atcggaagtt gctccaagcg ttaacggatt tagaccaaaa
    24421 tcgtaatatg agccagtctt ttgaatcagt ctcagatttg atggaggact tacgtgctta
    24481 agattcgtta tcataaacag tttaaaaaag attttaagtt ggctatgaag cgtggtttga
    24541 aggcagaatt attagaagaa gttttgaatt ttctggttca agaaaaagaa catcctgcca
    24601 gatatcgtga tcattcattg acggcatcca agcattttca aggagtttgt gaatgccata
    24661 cccagccaga ttggcttttg gtttataaag tagacaagtc ggaattgatt ttaaatttgc
    24721 tgaggacagg cagtcacagt gatttatttt aatctatttt aagggggttc tcatgaaact
    24781 aagaatattt gcggaagata agccggctaa gaaggtattt gaatatcaat tagaacttgc
    24841 tgatcgtaca attcttctat cgacagcact cttgtcaggt gctattgctt tagcaggaat
    24901 cttttctgct ttgagagaaa aataaaaata gaaaagagaa aacagaatgg ttttaccaaa
    24961 ttttaaagaa aatctagaaa aatatgcgaa attgttggtt gcgaacggaa ttaacgtgca
    25021 acctggtcac actttggctc tctctattga tgtggagcaa cgtgaattgg cacatctaat
    25081 cgtgaaagaa gcttatgcct tgggtgcgca tgaggtcatc gttcagtgga cagatgatgt
    25141 gattaaccgt gagaaattcc tccatgcccc gatggagcgt ttggacaatg tgccagaata
    25201 caagattgct gagatgaact atctcttgga gaacaaggct agccgtcttg gagttcgttc
    25261 atctgatcca ggtgccttga acggagtgga cgctgacaag ctttcagctt ctgctaaagc
    25321 tatgggactt gccatgaagc caatgcgaat cgcaactcaa tctaacaagg ttagctggac
    25381 tgtagcagcc gctgctggac ttgaatgggc taagaaagtc ttcccaaatg ctacgagcga
    25441 tgaagaagca gtcgatctcc tttgggacca aattttcaaa acttgccgtg tctacgaagc
    25501 agatcctgtt aaggcctggg aagagcatgc agctatcttg aagagcaagg ccgatatgct
    25561 taataaggag caattttcag cccttcacta cacagcgcca ggaacagatt taacacttgg
    25621 tttgccaaag aaccacgttt gggaatcagc tggtgctgtc aatgcacagg gcgaaggatt
    25681 cttgccaaat atgccgacag aagaggtctt cacagcgcct gacttccgtc gtgcagatgg
    25741 ttatgtcact tctacaaaac cgcttagcta caacggaaat atcatcgaag gtattaaggt
    25801 aacctttaag gatggacaaa tcgtagatat cactgctgag aagggtgatc aggttatgaa
    25861 agaccttgtc tttgaaaatg cgggtgcgcg tgccttgggt gaatgtgcct tggtaccaga
    25921 tccaagtcca atttctcagt caggcattac cttctttaac acccttttcg atgaaaatgc
    25981 gtcaaaccac ttggctatcg gtgcagccta tgcgactagc gttgttgatg gagcggagat
    26041 gagcgaagag gagcttgaag ctgcagggct taaccgttca gatgttcacg tagactttat
    26101 gattggttct aaccaaatgg atatcgatgg tattcgtgag gatggaacgc gagtacttct
    26161 tttccgtaat gggaattggg caaattaagg agataatatg ttaggaagta tgttcgttgg
    26221 tctcctagtg ggatttttag caggtgctat gaccaatcgt ggagagcgaa tgggatgttt
    26281 tggaaaaatg tttctcggtt ggatcggagc ctttctaggt cacttgctct ttggaacttg
    26341 ggggccagtt ttatcaggaa cagctattat cccagctgtt ttaggtgcca tgattgtctt
    26401 agctattttt tggagacgag gaagttaatt tcctaaatct gatactcaat gaaaatcaaa
    26461 gagcaaacta ggaaactagc cgcaggttgc tcaaagcact gctttgaggt tgcagataga
    26521 actgacgaag tcagtaacat atatacggca aggcgacgtt gacgcggttt gaagagattt
    26581 ttgaagagta tgaaacgaaa aggaggttgg tcattgtacc agcctccttt tgatatgata
    26641 taatagttct atgagattag ataaattttt agttgcctgt gcggtgggaa gtcggactga
    26701 ggtcaaaaac ttgctcaagg ctgggcgcgt gactgtaaat ggtaaaaaag aaaaatcagc
    26761 taaattgcag attgatgaaa aaatagatga gattcgcttt gatgggcaag tgttggagta
    26821 tgaagagttt gtctactaca tgatgaacaa gcccaaagga gttatctcag cgactgagga
    26881 tcccaagcac agaaccgttc tggacttgtt ggatgacttg gcgcggagta aggaagtttt
    26941 cccagtagga cgcttggata ttgacacgca tggtcttttg ctcttgacca ataatggtca
    27001 gctggctcat gttcttcttt cgcccaagcg tcatgtggac aagacttatc aggctcaggt
    27061 caagggaatt atgacccaag aagatgtgga gacatttatc aagggcattc cgctcaaaga
    27121 ctttacctgt cagcccgcta gactggagat tctttccaca gatgcagaaa agaatcagag
    27181 ccaaatccgt gtgaccattg cagaagggaa gtttcatcag atcaagcgta tggtgggcta
    27241 ctgtggcaag gaagtggtgg acttgcaacg attgactatg ggaactttag tattagatga
    27301 gaacctggaa cgaggggaat ggcgtcgctt gaccaaggaa gaattagaaa ttctccgcgc
    27361 taatattatt taatttagtt taatactcaa tgaaaatcaa agagcaaact aggaaactag
    27421 ccgcaggctg tacttgagta cggcaaggcg acgttgacgt ggtttgaatt tgattttcga
    27481 agagtataaa ttcgaaaaag gtgagggaca atgtcctcgc cttttatgtt ttttagttgc
    27541 ttcctttgtg aaaagagtta taatagactg tagaataaaa ggaggaatct atgaacgcga
    27601 ttcaagaatc atttactgat aaactatttg ccaactatga agcaaatgta aaataccaag
    27661 cgattgaaaa tgctgccagc cacaacggaa tttttgcagc tctggaatgt cgccaaagcc
    27721 atgtagacaa cacacctgtt ttctcattgg atttaaccaa ggacaaggtc actaaccaga
    27781 aagcgtctgg tcgttgctgg atgtttgcgg ctctcaacac cttccgccac aaactcatct
    27841 cgcaatacaa attggagaac tttgagttgt cacaagccca cactttcttc tgggataagt
    27901 atgagaaatc aaactggttc ttggagcaag tcattgcgac ttcagaccaa gaattgacta
    27961 gccgcaaggt tagcttctta ctccaaacac ctcaacaaga tggcggtcaa tgggatatgg
    28021 tcgtttccct ctttgaaaaa tacggtgtcg tgcctaagtc agtttatcct gagtctgttt
    28081 catctagcag cagtcgtgag ctaaatgcga tccttaataa attgcttcgt caagatgctc
    28141 aaatcttgcg tgatttgctt gtttctggtg cagatcaagc gactgttcaa gctaagaaag
    28201 aagacctctt gcaagaaatc tttaactttc ttgctatgtc attaggactt ccaccacgca
    28261 agtttgactt tgcttatcgc gataaagata acaactataa aagtgaaaaa ggaatcacac
    28321 cacaagagtt ttacaagaaa tatgtcaatc ttcctttaga agactacgtt tctgttatca
    28381 atgctccaac tgctgataaa ccttacggaa aatcttacac agttgagatg ttggggaatg
    28441 tggttggtag ccgtgcagtt cgctacatca acgttccaat ggagcgcttg aaagaattgg
    28501 cgattgccca aatgcaagca ggtgagactg tttggtttgg ttctgatgtc ggccagctca
    28561 gcaaccgtaa ggctggcatc cttgcgacag atgtttatga ctttgaatca agcatggaca
    28621 ttaaacttac tcaagacaag gctggacgtt tggactatag cgaaagcttg atgacccacg
    28681 ccatggtctt gacaggtgtt gacttggacg aaaatggtaa atcaaccaag tggaaggttg
    28741 aaaactcatg gggagacaag gtcggtacag atggttactt tgttgcctca gacgcttgga
    28801 tggacgaata cacataccaa atcgttgttc gtaaggaatt gctgacagca gaagaacaag
    28861 ctgcctatgg agcagaaaca atcgtacttg caccatggga tccaatggga gccttggctg
    28921 aataaaagca tagaaaaaag gaatcagatt ttagaacctg gttccttttt agttgcttga
    28981 ttacatgatg tgaagaacat gtgccacaat acccactgcg aagagggcaa ggataatagt
    29041 gattggagat acttttttct taagtaagta catgcaaagt aaagtaagga gtagtcctga
    29101 taatccagga atcaacatat ccaagttttg ttggaaagta gtaacttttt caggagtttg
    29161 agacaatcct tgtcctactt gtgcgaatgc ttcttggata cctttagacc cttctggcaa
    29221 tttatcccaa tggatataag ccttttcatc tagttgaact ttagaaacat cgaaagcaaa
    29281 tttaatattt acccagcgtt gaacaaggac agcaagaatg aacatcccaa ggatagaagc
    29341 tcctttagtg atatcttgaa ggataccacc agacatatct ttagtgattt ctgatccagc
    29401 cttgtatcca atctcttgaa cataccacaa gaatgacata cgaatcaagt tccatgcaac
    29461 aaagaagagg agtggaccca agatattgcc agtaagggca agtgaagcac cgagagatcc
    29521 aaggattggg cgcactgtaa accagaatac tgggtcaccg ataccagcaa gaggtcccat
    29581 cataccgatt ttaacccctt ggatagcagc gtcatcgatt tccacaccgt tagcacgttc
    29641 ttcttcaagc gcaagagtaa cccccatgac tggagcagct acgtatggat gagtgttgaa
    29701 gaactcaagg tgacgctcaa gagcagcgat ttgatcttct tttttagtat agagtttttt
    29761 gatagctgga atgagtgtat aagcccagcc caagttttgc atccgttcaa agttccaaga
    29821 cccttgtaag aaggttgaac gccaccaaac ttttttacga tctgatttag ttaattgaag
    29881 tttttcagtc atgatgtttt cagtcctttc ttatcttagt agtcttctag gatatcgccg
    29941 attgggtcgt tagaagttgc ggctcctccg ccaccatttc caccagtttt agaaaggtga
    30001 aggtagataa gagcgatagc aacaccgata gcaccgaatc cgattagagt aatatctgac
    30061 acagcagcga gaacgaaacc aagagcgaag aatggccata cttcacgagt tgccatcatg
    30121 ttgataacca tggcgtaacc aacggcaacg accataccac caccgatagc cataccatct
    30181 ttgagccagt ctggcatggc actaaggata ctttgtacag tttcagttgg taccataagg
    30241 agaagagctg caggaagcgc gatacgaagt ccttggaaaa gtagcgcaat gaaatgcgca
    30301 cgctccacag cgccgaagtc acctttttta gcggcagcat ctgcagtatg aaccaaacca
    30361 actgaaattg tacgaacaat cattgtcaag aaaagtccag ctacggcaag agggatagca
    30421 accgcttggg caacaccgat accagtcttg gtaaagtcac caccaagaac catgataatg
    30481 gcagcagcga cagaagcaag tgcagcatca ggagcgatag cagcaccgat atttgaccaa
    30541 ccaagggcaa tcatttgaag cgatccaccg aggataatcc ctgcttccaa gtgacctgtt
    30601 acaagcccaa taagggtaca ggctacaagt ggttggtgaa attggaactg gtcgaggatg
    30661 ccttcaagac ctgcaaagaa ggctacaacg actactaaaa ccatagaaat aatagacatg
    30721 tttaaaatcc tttcataaat aatggcttat ttgacattgg ctttgttaat caagtcaaac
    30781 aaatcttttt tagaatcatt tggtacttta cggacatcaa attcaacacc caagtcacgc
    30841 attttttcaa atgtagcaac atcttctttg tccatagaca aaacggtatt gaccaatgtt
    30901 ttacctgttg agtgagccat agaaccaacg ttaagagtct tgattggcac gccgccttcg
    30961 atggcacgaa gggcatcttg aggtgtttca aacaagataa gggcatgtgt ttctccaaaa
    31021 cgtgggtctt ttgaaatatc aatcagtttt tgaattggaa ccacgttagc cttgacatta
    31081 cctggagctg cttgtttaat caattcttta cgaaggtcgt ctttagccac gttatctgaa
    31141 gcaacgatga tacgatttgc ttttgaatct ggagtccaag cagttgcaac ctgaccgtga
    31201 agtagacgtg tgtcaagacg ggcaagattg attttcaatt taccgtctcc gataacagtt
    31261 ccttctggga tagcagcttg ggcaactgga gcagctgcag cgcttgcaac ttcttcaact
    31321 ggatttagct cttctggaag agctttgatg ccatctttgg cttctttaat gatattagca
    31381 acgacttttt ctacacctgc agcagcgtcc atgaggcgct ctgtgtaggc ttgaatcaac
    31441 atcggtaagt taagtcctgt gatgatggca aacttacgct caggattttc tcccatcacg
    31501 cgactagctt ggttaaatgg agaaccactc caaaggtcag ccaaaactag aacctcatct
    31561 tctgcgtcaa atgcagcaac agcgttatta aacttagcgt atagatcatc aggaccttca
    31621 tttggcataa aggtcacaac ttgaaccttt tcttgttcac caaagatcat agatcctgac
    31681 tgatgaatac ccgcagcaaa ttcgccgtgg ctcgcaataa tgattccgat actcattatt
    31741 gtcattcctc cttttttgtt ttagttttca tttaagaaaa ctttaagact gtttaagtat
    31801 aaaccgtttt cataaaaaaa gcaactattt atcataaaaa attaaaaaat ttttattttt
    31861 gtatgttgat atgttgagtt tttgaggagt aatcttgaat tcttatttaa aatttaatat
    31921 aaaaaagttg gaagaagctt ccaactttta aaataggttt ctattagatt agtgggtgaa
    31981 gtcgagtacc atacgtcctt ggatttggcc tttttccatt tcgtcgaaaa tggcaacagc
    32041 atcttctact ggacgttttt gaacaactgg gactaccaga ccttctgcac caaattggaa
    32101 ggcttcttct aagtctttac gagttccgac aagagaaccg atgacttgga ttccatcgag
    32161 gactgtttta acgatgctga gttccatcat ttcagaagga agaccaacag cgacgacgcg
    32221 accaccagca cgaatggagt caacagcctg gttgaaggca actttagaca cagcagttac
    32281 gacagctgaa tgagctcctc catcagtttt ttctttaatg agtctagcta catcttcaac
    32341 ttcgaggccg ttaatcacaa tgtcagcgcc tacttctttt gcaagggcaa gtttgtcatt
    32401 gttgatatcg actgcgataa catgagcatt gaatactttt ttagcgtatt gaacagcgag
    32461 gttaccaagt ccaccagcac cgtaaagaac aacccattgg cctggttcaa cttttgcttc
    32521 tttgatagct ttataggttg ttactccagc acatgtgata gaagaagctt gggctggatc
    32581 aagtccgtca ggaaccttga cagcatagtc agcagttacg atacattgtt cagccatacc
    32641 accgtctact gagtagccag catttttcac tgtacggcaa agggtttcgc gaccagttgt
    32701 acagtattcg caagtgccac atccttcaaa gaaccaagca acgctgacgc ggtcaccgac
    32761 tttaaggctt ttcacatctg gagcaatctc tttaacgata ccgatacctt cgtgcccaag
    32821 aacacgtcct gggacttgac caaagtcacc atgagcaacg tggaggtcgg tgtggcaaac
    32881 gccacagtat tcaacttcta caagtgcttc cccagtttca agtggacgga gtactttttc
    32941 ttcaatagca acaccagtgc tttctggatt tacaacaaca gctttcatag ctatcctcct
    33001 tgatattgac cgagaacagg gacaacggga ctggattgat tttttgtcaa cagagtcgag
    33061 tgtgacgagc tctcttgtat ttatatgtga agtatatcac aaaagaaagc cttttccaag
    33121 gttttggaga caaaaagtag aacaatcgat taactggttg atgagactgt gaaaagagca
    33181 caaagaccag cttgcaagct ggtcatactc ttcgaaaatc tcttcaaacc acgtcagctt
    33241 catctacaac ctcaaagcag tgctttgagc aacctacggc tagcttccta gtttgctctt
    33301 tgattctcat tgagtatcag tataggttat aagaataagt cttgtagggt tttggcaacc
    33361 ccatcttggt cgttggtaag ggaaatttgc tcatctgcat aagggagtag ctctggattg
    33421 gcatttttca tggcataacc cttcccagca aaagcgagca tttcggtatc attgtgttca
    33481 tctccaaagg caatcaaatc ttttttgtca cgattcatta tcttgagcaa gtagtccaaa
    33541 gcaaaggcct tgttgacacc ttttggggta cattcaagga tattgagcgg acctccccag
    33601 gtattgatag aaagttgatg ctggtagaag gcgttcatgt cttttgccaa ggcatatttg
    33661 tcactggctc tggtctgcaa gaggatacag ttagggttct tggtcaccaa ttcaggctgg
    33721 aattgatctt caggctggaa agcttctaca ccaaatagtt tgggattggc aatttcttca
    33781 ttgggatttg taatgtagaa ttttttacga tattctccag cgataaaatc ggcttgaatg
    33841 tcctctgaac gttgaaccat atctagcaga tattttttgt ctacagtcaa acacttttca
    33901 aaatcccaaa cttggtctgg taaatgagta agggatccgt tgaagttaat cataggagtg
    33961 tctaagccca gttcacggta aaaatctttt gacatacggt aagggcgacc tgtcgtaata
    34021 ataacctgat ggcctttttc agcaactttt ttgatggttt ttttggtaaa gtcagaaatt
    34081 tgactgtctg agttgagcag ggttccatcc aggtcaactg caataatttt tttcgtcata
    34141 tggacctttc tagtgtgttt tcagataaga tgtcttctat tataacagaa agcaggcaga
    34201 aaagcagatt ccaaacaaaa aatgaaattg gattaatttc ttaaacaaat caaacaaaga
    34261 cattgaaaaa gtgaatgata aatgatataa ttctattatt gttcgtaaaa attaaaagga
    34321 gattgatgat ggacaaatta tttaaactaa aagagaacgg tacagacgtt cgtacagagg
    34381 ttctcgctgg tttaacaact ttctttgcaa tgagctatat tctctttgta aacccacaaa
    34441 tactttcaca aacaggaatg cctgctcagg gcgtcttcct agcgacgatt attggtgcag
    34501 tagcgggtac cttgatgatg gctttttatg ctaacttacc ttatgcccaa gcgccaggta
    34561 tgggactcaa tgccttcttt acctttacag ttgtattcgg gcttggttat tcttggcaag
    34621 aagccctagc tatggtcttc atctgtggga ttatttcatt gattattacc ttgacaaatg
    34681 ttcgtaaaat gatcattgaa tcgattccca atgctcttcg ctcagctatt tcagctggta
    34741 tcggtgtctt ccttgcctat gtagggatta agaatgctgg acttttgaaa ttcacgattg
    34801 atccaggcaa ctatactgtt gtaggagaag gggctgacaa agctcaagca acgattgcag
    34861 caaactcttc agcagttcca ggattggtca gctttaataa tccagctgtt ttagtggctc
    34921 ttgcaggact tgccattact atcttctttg tcatcaaagg gattaaaggg ggaattattc
    34981 tctctatctt gacaacaact gttcttgcta ttgcagttgg tttggttgat ttgtctagta
    35041 tcgattttgc taataaccat gttggtgcag cttttgaaga tttgaagaca atctttggtg
    35101 cagctcttgg ttcagaaggt ttgggagctt tggtttcaga tacagctcgc ttgcctgaaa
    35161 ctctgatggc cattcttgcc ttctcattga cagatatttt tgacacaatt ggtaccttga
    35221 tcggtacagg tgaaaaagtt ggtatcgtag cgacaaatgg tgaaaatcac caatcagcca
    35281 aattggataa ggctctttac tctgatttga ttggaacgac agtcggtgcc attgcaggta
    35341 cttcaaacgt aacgacttat gttgagtctg ctgctggtat cggtgcaggt ggacgtactg
    35401 gtttgacagc cttggttgta gctatctgtt ttgcgatttc aagcttcttt agcccacttc
    35461 tagcgatcgt accaacagcg gctacagctc caatcttgat tatcgttggg attatgatgc
    35521 ttggtagctt gaaaaatatc cattgggatg atatgtctga agcagttcct gccttcttca
    35581 catctatctt tatgggattc agctactcta tcactcaagg gattgcagtt ggtttcttga
    35641 cttacacttt gactaagctt gttaaaggtc aagttaaaga tgttcatgtc atgatttgga
    35701 ttttggatgc cttgtttatc cttaactaca tcagcatggc cttataatag aatgacccag
    35761 ggggatttcc cccctttttt aatacaaaag gagataggtg atgaaagaga aaaatatgtg
    35821 gaaagaattg ttgaatcgtg caggctggat tttggtcttt ttacttgccg tccttttata
    35881 tcaggttccc ctagtggtta cctctatttt gactttaaaa gaagtagccc tgctacagtc
    35941 agggctgata gttgctggcc tttcaattgt ggttctggct ctatttatta tgggagctcg
    36001 taaaaccaag ttagctagtt ttaatttttc tttttttaga gctaaagatt tggcacgttt
    36061 gggcttgagt tatttagtta ttgtcgggtc aaatatactt ggttccattt tattgcaaat
    36121 gtcaaatgag acgacaacag ctaaccagtc tcagattaat gatatggttc aaaatagttc
    36181 gttgatttcc agtttcttct tgctagcctt gcttgctccg atttgtgagg aaatcttgtg
    36241 tcgtgggatt gttcctaaaa agatttttcg aggcaaagag agctggggat ttgtagtcgg
    36301 tacgattgtg tttgctttat tacatcaacc aagtaattta ccttctttat tgatttatgg
    36361 aggtatgtcg acagttctat cttggacagc ctacaagacc caacgtttgg aaatgtcgat
    36421 cttacttcac atgattgtta atgggattgc tttctgtttg ttggctcttg tggtgattat
    36481 gagtcggaca ttagggattt ctgtttaaga ttattgacaa ttgcttactt gtttctactg
    36541 ggagaaagat gaatgaaatc gtgtccatct ttttcttttt atggtaaaat agagaaataa
    36601 tatgatgaaa agccttgagg gagtgaccga tatgtcaagt aaagccaatc atgcaaagac
    36661 agctatttgc ggaattatca atgtaacccc agactccttt tcggacggtg gtcaattttt
    36721 tgctcttgag caggcgctcc agcaggctcg taaattgata acagaaggag ccagtatgct
    36781 cgatatcggc ggagaatcga ctcggccggg aagtagctat gttgagatag aagaggaaat
    36841 ccagcgtgtt gttccagtga tcaaagcgat tcgcaaggaa agtgatgtac tcatttctat
    36901 cgatacttgg aaaagtcagg tggcagaggc tgctttggct gctggtgcca atctagttaa
    36961 tgatatcact ggtctcatgg gcgatgaaaa aatggctcat gtggttgcta aagctggagc
    37021 gaaagtagtc atcatgttta atccagtcat ggctcgacct caacacccta gctcgctcat
    37081 attccctcat tttggattta atcaaacttt tacagtagaa gagttagctg actttgaaac
    37141 attgccaatc gaagacttga tggtggcttt ctttgaacga gcactagcga gagcggcaga
    37201 agctggtatt gcaccagaaa atatcctgtt ggatccagga attggctttg gtctgaccaa
    37261 gaaagaaaat ctcctccttt tacgggacct ggataaacta catcagaagg gctatccaat
    37321 ctttctcgga gtgtcgcgca agcgatttgt catcaatatc ctagaggaga atggttttga
    37381 agtcaatcct gagacagagc ttggtttccg aaatcgggac acggcttcgg ctcatgtaac
    37441 tagtatcgct gcgagacagg gtgtagaagt ggtgcgcgtg catgacgtag ctagtcacag
    37501 gatggcagtt gaaattgcct ctgccattcg tctggctgat gaagcggaaa atttagattt
    37561 aaaacaatat aaataagatg aaagaaattg aaaacaatca gtggattgct aactaccgga
    37621 cggatcaacc gcattttggc ttggaacgaa tggtggaact gttagctttg cgtggcaatc
    37681 cccatctcaa actcaaggtc ctccatatcg gagggactaa cggcaaggga tcgactattg
    37741 cttttttgaa aaagatgcta gaaaagctag ggctgagagt tggcgtgttt agctcgccct
    37801 atctcattca ttacacagac cagattagca tcaatgggga atcgatctca gaagcgaggc
    37861 tagaagctct catggcagac tatcagtctt tgctggaggg agaagcggtc gccaatttac
    37921 agggcacaac cgagtttgag attatcacag ccctggccta tgactacttt gcctcagagc
    37981 aagtagatgt ggccatcatg gaagttggca tgggtggact ttttgatagt accaatgtct
    38041 gtcagcccat tttgacagga attacaacta ttggcttgga tcatgtggcc ttacttggtg
    38101 acaccttgga ggccatagca gagcagaagg caggtattat caaacaaggg atgcccttgg
    38161 taacagggcg tattgctcca gaagccttgg ctgtgattga ccgcattgcg gaagggaaag
    38221 atgcgccgag acttgcctac gggacagatt atcaggttcg tcatcaagac agtgtggtga
    38281 caggggaagt ctttgactat acaagtgctg tcagacaagg tcgcttccag actagcctgc
    38341 ttggtttgta ccaaatagag aatgctggga tggccatagc tttacttgat actttttgtc
    38401 aagaagatgg tcgagagcta gcaagcaatg actttcttgg tcaagccttg gaagaaacaa
    38461 gttggccagg gcgtttggaa atcgtgtcaa gagatccctt gatgattttg gatggagccc
    38521 ataatcccca tgctatcaag gccttgttgg taaccttgca agaacgtttt gcggattatc
    38581 ataaggaaat cctcttcact tgtatcaaaa ccaaagcctt ggaggatatg ttggacttgc
    38641 tgggagccat gccagatacc gagcttactc taacacattt tgcggatagt cgggcgacgg
    38701 atgaaagcgt gctgaaagag gcagctaagt ctagaaatct cagctaccaa gattggcatg
    38761 attttctaga gcagaatgtg acagataaaa aagaagagaa acaaacagtt aggattgtca
    38821 caggttcctt gtatttcttg agccaagtga gggtctatct gatggagagg aagaacgaga
    38881 atggatacac aaaagattga agcagctgta aaaatgatta tcgaggctgt aggagaggac
    38941 gctaatcgcg agggtttgca ggaaacacct gctcgtgtag cccgtatgta tcaagagatt
    39001 ttttcaggtc ttggtcaaac agcagaggaa catttgtcaa aatcctttga aattattgac
    39061 gataatatgg tggtagaaaa ggatatcttt ttccatacca tgtgtgaaca ccacttcttg
    39121 ccattttatg gtagagcgca cattgcctac attccagatg gtcgtgtggc aggcttgtct
    39181 aagctagccc gtacggttga agtttattcg aaaaaaccac aaattcaaga acgtttgaat
    39241 atcgaagtgg ccgatgcctt gatggactat ctaggtgcta aaggagcctt tgttatcatt
    39301 gaggcggaac atatgtgtat gagtatgcgt ggtgttagaa aaccaggcac tgcaaccttg
    39361 acgacagtag ctcgtggtct atttgaaaca gataaggacc tccgcgacca agcttatcgt
    39421 ttaatggggc tataaaaaga atccgtttca agcggatttt tctagaaagg aatcattatg
    39481 gatcaactgc agattaagga tttggaaatg tttgcctatc atggtctttt tcctagtgag
    39541 aaagaattgg ggcagaaatt tgtcgtttca gccatcctat cctatgatat gaccaaggca
    39601 gctacagact tggatttaac agcctctgtc cattacggag aattgtgtca gcagtggacg
    39661 acttggtttc aggaaacgag tgaagatttg attgaaacgg tagcctataa actggtggaa
    39721 cgtacctttg agttttatcc tcttgtccaa gaaatgaagt tggaactgaa aaaaccttgg
    39781 gcaccggtgc atttgtcact agatacttgc tcggtaacca ttcatcgccg caagcaacga
    39841 gcctttatcg ccttaggaag caatatggga gataaacaag caaacttgaa gcaagccatt
    39901 gacaaactgc gagctcgtgg catccatatt ctcaaagagt ccagtgtctt agcgacggag
    39961 ccttggggtg gagtggagca ggatagcttt gccaatcaag tggttgaggt ggaaacctgg
    40021 ctaccagcac aagacttgtt agaaaccttg ttagccattg agtcagagct gggacgggtg
    40081 agagaagtgc attggggacc tcgtttgatt gatttggact tgctctttgt ggaggaccag
    40141 atcctttata cagacgacct catattgcct catccttaca tagcggaacg cctttttgtc
    40201 cttgagtcct tacaggaaat tgcgcctcat tttatccatc cgatattaaa acaaccgatc
    40261 cgcaacttgt atgatgcttt gaaaaaatag aaaaactcta gttttcagtc acttgcaact
    40321 gaaggctaga gtttttaaaa taggttattt tcttctggga ggaggatagt ttctctaccg
    40381 tccatgtcta aaaccagtac tcttggggga taacgagggt cgaaaggatg gttaaagtca
    40441 aaatcaatgg ctgtagggag gtgttgactt gaaaagtgga aggtaatctt tccttggtta
    40501 ttaagcaatt gaaactcgag ttcttcttcc aattcaaaga cattttttaa gaaatggtcg
    40561 atgatatacc aaaaagagtc aatgatgtca tcaggcaagc tggtaacaat gccaaaacta
    40621 gcagaccgca tgtgggtatt ggtaaaagcc atatatctgt cccctttctt ttcccttatc
    40681 atacagcaaa taggattaaa aatcaagaaa aggtgatttt ttgaaaagga ttttagttac
    40741 agggagaaat agggaaaaat tcccaaaaat ctaccgaagt taataggtaa cttcccaaat
    40801 taacttgatt atataacttt cagttatttt gagaagttac cgaaaaatat ttttcatatc
    40861 tattgacttt taggggtgaa atttggtatg atagtaggcg gtattgttta ccccatttga
    40921 aaggccccgg aaccttccaa atacttttcg atgggaagga acacccatca ccgtaaacaa
    40981 aaatcgaact atatatagga gaaatcatga acaaaacaac atttatggct aaaccaggcc
    41041 aagttgaacg taaatggtac gtagttgacg caactgatgt accacttgga cgtctttctg
    41101 cagtagttgc tagcgtactt cgcggaaaaa acaaaccaac atttacacca cacactgata
    41161 caggtgactt cgtgattgtt atcaatgctg aaaaagttaa attgactggt aaaaaagcaa
    41221 ctgataaaat ctactacact cactcaaacc acccaggtgg attgaaacaa atctctgcag
    41281 gtgaacttcg ttctaaaaat gcagtacgtt tgattgagaa atcagttaaa ggtatgcttc
    41341 cacacaatac acttggacgc gctcaaggta tgaagttgaa agtatttgtt ggagctgagc
    41401 acactcacgc tgcacaacaa ccagaagttc ttgacatttc aggacttatc taaggaaagg
    41461 aacaataaag tatgtcacaa gcacaatatg caggtactgg acgtcgtaaa aacgctgttg
    41521 cacgcgttcg ccttgttcca ggaactggta aaatcactgt taacaaaaaa gatgttgaag
    41581 agtacatccc acacgctgac cttcgtcttg tcatcaacca accattcgca gttacttcaa
    41641 ctgtaggttc atacgacgtt ttcgttaacg ttgtaggtgg tggatacgct ggtcaatcag
    41701 gagctatccg tcatggtatc gctcgtgccc ttcttcaagt agacccagac ttccgcgatt
    41761 cattgaaacg cgcaggactt cttacacgtg actcacgtaa agttgaacgt aagaaaccag
    41821 gtcttaagaa agctcgtaaa gcatcacaat ttagtaaacg ttaattcgaa agaattacta
    41881 tacttataca gagcaccttt cggggtgttc tttttttata ctttcttact aaattggtgc
    41941 aattgacaca gttgttgcga ctttagtcgc ttacaaatgt ggctgcaacc tgacaaggtc
    42001 agttgcctca aaacgttaat caatacgatt atatcaacgt ttcaaagcac tcaaaagttt
    42061 accttatggg tgcttttgtc ttgttcttgt ttcaattgac tataaatcgc tataagaaaa
    42121 aatcatttta ttggtataaa gaagtgattg aaagtaatgg cgaaacgtta gataattagt
    42181 tcataaaaaa caagtttaga tcctcatcta aacttgtttt ttaaaaattg aaggatgatt
    42241 ttggaggata taagatgaca ttgactattc atgtatatta taaaggtgat ggagatagtg
    42301 caataaagtt tgcaagagaa atgcttgata gtggccttgt tgaagaaatt agaaatcaaa
    42361 aaggtaactt gaaatacgaa tattttttac caattgaaaa agagggaact attctcctta
    42421 ttgatcagtg gataaatcaa gaagctttag ataagcatca tcaatcaaag acaatgcaga
    42481 aaatcttaga tttaagaaaa aaatatcact tgcagatgca agttgaacgt tatatagaag
    42541 atgattctgg gatgccagaa agcgataagt cgtttataga cacagggaat tagaattatt
    42601 gtgagagttt ttgtagtttg aaagtattga aaatcgtaaa gatatcatta cgagaataca
    42661 agaagatatt gttctatttc cattaaaaat tacttctttc cttaacaata aggaaaaaga
    42721 atgcgttttc atcttttggt ttgaggttta taataagagt atcaaagtca ggaggaaaaa
    42781 agatgactac ttttaaagat agatttttat ggggtggtgc tgttgctgct catcaacttg
    42841 aaggtggatg gcaagaaggt ggcaagggaa ttagtgttgc tgatgttatg actgctggtc
    42901 gtcatggagt agctcgtgaa attactttgg gagttttaga gggtaaatat tatccaaatc
    42961 atgaggcgat agatttttat catcgttata aagaagatat agcacttttt gctgaaatgg
    43021 gattcaagtg cttccgtacc tctcttgcat ggacacgtat ctttccaaaa ggtgatgagt
    43081 tagagccgaa tgaagaagga ttacagtttt atgataatct ttttgatgaa tgcttaaaga
    43141 atggtattga acctgtcatc actctatctc attttgaaat gccttatcac ttagtgaccg
    43201 aatatggtgg ttggaaaaat aggaaattga ttgatttctt tgctcgtttt gcagaagtcg
    43261 tatttaaacg ttacaaagat aaggttaaat attggatgac tttcaatgaa atcaataatc
    43321 aagcgaatta tcaggaagat tttgcaccat ttactaactc aggtattgta tatgaggaag
    43381 gtgataatag agaggcaatt atgtatcaag cagtacatta cgaattagtt gcttctgcac
    43441 gagctgtaaa aattggtcat gagattaatc cagattttca aataggttgt atgattgcga
    43501 tgtgtccaat ttatccagct acttgcaatc ctaaggatat cttaatggca atgaaagcta
    43561 tgcagaagcg ttattatttt gctgatgtgc atgttttagg taaatatcct gagcatattt
    43621 tcaagtattg ggaacgaaaa ggtatttcag ttgattttac tgcccaggat aaagaagatt
    43681 tacttggtgg gactgtagat tacattggtt tcagttacta tatgtccttt gctatcgact
    43741 ctcatcgtga aaataatcct tattttgatt atcttgaaac agaagattta gtgaaaaata
    43801 attatgttaa ggcttctgaa tgggagtggc aaattgatcc agaaggttta cgttatgcgt
    43861 taaattggtt tacagaccac tatcacttac cactctttat tgttgaaaat ggttttggag
    43921 ctatagatca agttgcagca gatggtatgg tacatgatga ttatagaatt gaatatctag
    43981 gtgcccatat tcgtgaaatg aaaaaggctg tagttgaaga tggtgttgat ttaatgggtt
    44041 atactccatg gggatgtatt gatttggttt cagctggtac cggtgaaatg cggaaacgtt
    44101 atggctttat ttatgtagat aaagatgaca atgggaaggg aagttataat cgttccccga
    44161 aaaaatcttt tggctggtat aaggaagtta tttcatctaa cggtgaatca gtagaatagt
    44221 ataaacaaac tgagattatt ctcagtttgt ttagcatatt gaggtgacat atgattggaa
    44281 gtattgcagc aattttaaca acatttgcat ttttaccaca agtttttcgt gtagttaaga
    44341 caaaggacac aggaactatt gctctaggta tgtatgttat gcaagttatt ggtattgcat
    44401 tgtggcttgc tcatggtatt cgtataggag acttgccttt gattttagca aatagtgttt
    44461 catttctact ctcaggaata attttatttt ataaattgaa gtataaataa tttttttcca
    44521 tatcatttag gaaaatgagg gaattgtcat tggaaacgct ttattttata ataaaaatag
    44581 ataacaaata agccaactta gcacagcttt gattggattt aagaaaagga gaaaatatta
    44641 tggcaaaagc tttaattatt tgtgcagcag gaatgtcttc atcacttatg gcacagaaaa
    44701 caacagagtt tctaaaagga aaagggaaag atattgtagt tgatgctatt agtgctactg
    44761 aaggagggaa agctatcgca gcagcagctt ttgatttgta tcttgtcagc cctcaaacaa
    44821 aaatgtactt taagcaattt gaagaggctg gttctaaagc aggaaaacca gttgtacaaa
    44881 tacctcctca agcatatatt cctattccaa tgggaattga aaaaatggct aatttgattc
    44941 ttgagaatat ttgatgaaca catgaaatgt caataaatat ttaggttaag ataaattgtt
    45001 ttgagtttga tataaactga tttaagtgta taatatgctt caatatatga aaacatacgt
    45061 tttaggaggg aatgaatgtg ttaaacatta aagagaaaga tatccttcaa tttttaataa
    45121 aaaataagga acgttttgtt acaagcaaag aactggcaga atatttatcc tgttcagata
    45181 gaactgtccg taatgtactg aaattaattg agaagacaat gattattcaa ggagtccggt
    45241 tgatttcaaa acaaggtcaa gggtatcaaa tattttttga gaatcaaggc gcttaccagg
    45301 agtttagaca aacttatgaa ctggaagaag actatacgaa aactgcggtt tcaaaaggtg
    45361 atgatcgttt agtatttatc ttaaataaat tattatttga gcaagttcca gttctttttg
    45421 atgatttagc tgatgaactt tacgttagcc gttcaacatt atctcatgat ttcagaaaga
    45481 tacgagtgat gttatcagag tataatttgt ccattgagag tagggcgaat aaaggagttt
    45541 atgtctcagg cgaggaacgt gataaacgac gttttatcat aaattatttc ctagagaatc
    45601 aattttttaa aacaatacat tgctatgtaa aatttaactt ttttgatcaa actgttccat
    45661 tagaagaatt tgctagaatt gttttggatg aatgccaaga ggccaaccta aaactatctg
    45721 attttgtact acagaattta gtagttcaca tagcattgtc tgtgattcgt ttaaaattcg
    45781 gatttgaaat aaaaaatata gactgtcaga tgactgatga tgcaatagag agaaaggttg
    45841 cccaaagaat tctttctaaa gtaagagaag taacaaatca ggaatttcca gttcaggaaa
    45901 tagactacat tactttgcat ttgttagcta agagtcaaca atgtcaaaaa aatcagaaga
    45961 atatttctga agaagtttta aaaaaatctt tatttaaaac atttcagaat ttaggattag
    46021 atgatatgta taacttttct tcagatttcc aactaattga aggattgata actcatctaa
    46081 tgacactaca agtacgttta gaaagccgga ttaccttaaa taaccctttg gtagatgaaa
    46141 ttaaacagaa ttatagtgat atattcttta tgactagaga aattcttgca aatatggaca
    46201 agttcttgga gtggacaata tcagatgatg aagtagcata tgtaagtctt cactttttag
    46261 ctgctatgga acgtagcaaa gagagtacta agtttaatat tcttgctatt tgtgcaacag
    46321 gatttggtgc agcccaaatg ttaagaaatc gtttggaaac ggagtttggg aagcgagtag
    46381 aagttgttga tgtaataggc tattatgaat tgaatcaaga aaaacttaaa ggaatagatt
    46441 ttatagtgtc agctgttgat ttatcaaatc tatattttca aatcccagtt tttaaagtta
    46501 gtgtgtttct taagagtgat gagatggaaa tgattagaaa agctatggtt cagatgcaag
    46561 tttctagtta tgtacaatca tcaaagatta acaaatttga aaacaacggc tttagacagt
    46621 attttagtaa agaaaacttt ttaatatgta ctgaatcaga caaggtaaat ttacttgaaa
    46681 agatggttga gagtttatct gttggtgaat caaatgagtt tgaacaatct ttactttatg
    46741 gaattaaaca gcgcgaagaa ttaagttcag ttgttttttc tgaaaaaatt gcagttccgc
    46801 atcctattca gccctttggt acagaggaaa aggtttcggt tgcaatttgt aaagattcgt
    46861 tactctggga taatcaaagt tcacatgtcc agctagtatt tcttctatct ccatcaatat
    46921 atgggaacga aggtttggca actgtgacta aaaagatagt ctctctgaca gagaatgatg
    46981 aattgcaaaa tcagctaata tcttgcaata actttgaaga ttttattaac atatttgaga
    47041 agataaaata ggaggttcat atgaatcaag aggaactgca ggttgcagca tttgaaatta
    47101 tcctgcattc gggaaatgca aggtcagaaa tacatgaagc atttgcaaaa atgagagaag
    47161 gtagttttga tgatgcagaa agtaaattaa atcaatcaaa tgagataatt cttgaagcgc
    47221 atcatgcaca aaccaaactc ttgcaagaat acgcaagtgg agtggaaatt aaaattgaaa
    47281 ttatcatggt acatgctcaa gatcatttaa tgaccactat gacattatta gaagtagcaa
    47341 aggaaatgtt agctctttat aagaaagtta actaaatatg tgttgttata taaggaggaa
    47401 atgatatgga taaaaaagaa cgacaaaaga ttgaacaaca acgtcgagag atggctctaa
    47461 ctaatacttt ttttaatcga tatcttcttc tacgttattc aatagcactc ttcttttttg
    47521 ggaatattta ttggcttttg aatcagttta ttaatccctc gcctattatt attttcccca
    47581 ttatgctcat agtattttct attttagcaa ctattgaaca atttaaactt tatggaaata
    47641 ggaaagaaaa gttgggaata acactaatgt ttgttagaat acaaatgctt atttcaatag
    47701 gattacttgt tttaacttgg acaagttggt ttaagaatct ttttccgatt tttgaaaata
    47761 accaagtagc acgtttattt gtttttgtag ttcttctatt aggtttagtt ctgagtttgt
    47821 tagacattag aagaattaaa aaaatttata aacgaacaga taaggtttat caacaatttg
    47881 tccaattgga aaagaactca cttagtttat aatcctgatc tagtataatt tgtattt
//
LOCUS       DAVKBC010000011        46718 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVKBC010000011 DAVKBC010000000
VERSION     DAVKBC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46718
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.011"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(65..1732)
                     /locus_tag="VWX64_000707"
     CDS             complement(65..1732)
                     /locus_tag="VWX64_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU9190231.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(1735..2100)
                     /locus_tag="VWX64_000708"
     CDS             complement(1735..2100)
                     /locus_tag="VWX64_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9190232.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(2257..2445)
                     /locus_tag="VWX64_000709"
     CDS             complement(2257..2445)
                     /locus_tag="VWX64_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU9190233.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(2561..3046)
                     /locus_tag="VWX64_000710"
     CDS             complement(2561..3046)
                     /locus_tag="VWX64_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU9190234.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(3474..5018)
                     /locus_tag="VWX64_000711"
     CDS             complement(3474..5018)
                     /locus_tag="VWX64_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU9190235.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLELLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            5231..5533
                     /gene="gatC"
                     /locus_tag="VWX64_000712"
     CDS             5231..5533
                     /gene="gatC"
                     /locus_tag="VWX64_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU9190236.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            5533..6999
                     /gene="gatA"
                     /locus_tag="VWX64_000713"
     CDS             5533..6999
                     /gene="gatA"
                     /locus_tag="VWX64_000713"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU9190237.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMNEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            6999..8441
                     /gene="gatB"
                     /locus_tag="VWX64_000714"
     CDS             6999..8441
                     /gene="gatB"
                     /locus_tag="VWX64_000714"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU9190238.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            8570..9130
                     /gene="efp"
                     /locus_tag="VWX64_000715"
     CDS             8570..9130
                     /gene="efp"
                     /locus_tag="VWX64_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU9190239.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            9152..9541
                     /locus_tag="VWX64_000716"
     CDS             9152..9541
                     /locus_tag="VWX64_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9190240.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            9534..9956
                     /gene="nusB"
                     /locus_tag="VWX64_000717"
     CDS             9534..9956
                     /gene="nusB"
                     /locus_tag="VWX64_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU9190241.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(10005..10613)
                     /locus_tag="VWX64_000718"
                     /pseudo
     CDS             complement(10005..10613)
                     /locus_tag="VWX64_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520572.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(10631..10816)
                     /gene="briC"
                     /locus_tag="VWX64_000719"
     CDS             complement(10631..10816)
                     /gene="briC"
                     /locus_tag="VWX64_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU9190242.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(10975..11742)
                     /locus_tag="VWX64_000720"
     CDS             complement(10975..11742)
                     /locus_tag="VWX64_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU9190243.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(11739..12605)
                     /locus_tag="VWX64_000721"
     CDS             complement(11739..12605)
                     /locus_tag="VWX64_000721"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU9190244.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     FMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(12642..14009)
                     /gene="accC"
                     /locus_tag="VWX64_000722"
     CDS             complement(12642..14009)
                     /gene="accC"
                     /locus_tag="VWX64_000722"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU9190245.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(14021..14443)
                     /gene="fabZ"
                     /locus_tag="VWX64_000723"
     CDS             complement(14021..14443)
                     /gene="fabZ"
                     /locus_tag="VWX64_000723"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU9190246.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(14440..14925)
                     /locus_tag="VWX64_000724"
     CDS             complement(14440..14925)
                     /locus_tag="VWX64_000724"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU9190247.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(14928..16163)
                     /gene="fabF"
                     /locus_tag="VWX64_000725"
     CDS             complement(14928..16163)
                     /gene="fabF"
                     /locus_tag="VWX64_000725"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU9190248.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(16185..16916)
                     /gene="fabG"
                     /locus_tag="VWX64_000726"
     CDS             complement(16185..16916)
                     /gene="fabG"
                     /locus_tag="VWX64_000726"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU9190249.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(16950..17870)
                     /gene="fabD"
                     /locus_tag="VWX64_000727"
     CDS             complement(16950..17870)
                     /gene="fabD"
                     /locus_tag="VWX64_000727"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU9190250.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(17863..18837)
                     /gene="fabK"
                     /locus_tag="VWX64_000728"
     CDS             complement(17863..18837)
                     /gene="fabK"
                     /locus_tag="VWX64_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU9190251.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(18956..19180)
                     /locus_tag="VWX64_000729"
     CDS             complement(18956..19180)
                     /locus_tag="VWX64_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9190252.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(19239..20213)
                     /locus_tag="VWX64_000730"
     CDS             complement(19239..20213)
                     /locus_tag="VWX64_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU9190253.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(20213..20647)
                     /locus_tag="VWX64_000731"
     CDS             complement(20213..20647)
                     /locus_tag="VWX64_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9190254.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(20741..21526)
                     /locus_tag="VWX64_000732"
     CDS             complement(20741..21526)
                     /locus_tag="VWX64_000732"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU9190255.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            21851..23215
                     /locus_tag="VWX64_000733"
     CDS             21851..23215
                     /locus_tag="VWX64_000733"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU9190256.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRELTPIKEEEILRQLVQKTKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGK
                     SKED"
     gene            23218..23589
                     /locus_tag="VWX64_000734"
     CDS             23218..23589
                     /locus_tag="VWX64_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU9190257.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            23803..25077
                     /gene="serS"
                     /locus_tag="VWX64_000735"
     CDS             23803..25077
                     /gene="serS"
                     /locus_tag="VWX64_000735"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU9190258.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(25102..26001)
                     /locus_tag="VWX64_000736"
     CDS             complement(25102..26001)
                     /locus_tag="VWX64_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU9190259.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(26111..26659)
                     /locus_tag="VWX64_000737"
     CDS             complement(26111..26659)
                     /locus_tag="VWX64_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU9190260.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(26877..28199)
                     /locus_tag="VWX64_000738"
     CDS             complement(26877..28199)
                     /locus_tag="VWX64_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU9190261.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFTALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSQVVIAETKKYFDK"
     regulatory      complement(28290..28378)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(28542..30878)
                     /locus_tag="VWX64_000739"
     CDS             complement(28542..30878)
                     /locus_tag="VWX64_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU9190262.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRVLKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(30982..31530)
                     /locus_tag="VWX64_000740"
     CDS             complement(30982..31530)
                     /locus_tag="VWX64_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU9190263.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(31527..31829)
                     /gene="zapA"
                     /locus_tag="VWX64_000741"
     CDS             complement(31527..31829)
                     /gene="zapA"
                     /locus_tag="VWX64_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU9190264.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            31916..32797
                     /locus_tag="VWX64_000742"
     CDS             31916..32797
                     /locus_tag="VWX64_000742"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU9190265.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            32801..33415
                     /gene="lepB"
                     /locus_tag="VWX64_000743"
     CDS             32801..33415
                     /gene="lepB"
                     /locus_tag="VWX64_000743"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU9190266.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            33542..35908
                     /locus_tag="VWX64_000744"
     CDS             33542..35908
                     /locus_tag="VWX64_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU9190267.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMILAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQTCMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(35956..37239)
                     /locus_tag="VWX64_000745"
     CDS             complement(35956..37239)
                     /locus_tag="VWX64_000745"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU9190268.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(37433..37792)
                     /locus_tag="VWX64_000746"
     CDS             complement(37433..37792)
                     /locus_tag="VWX64_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9190269.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPIIAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(38091..39005)
                     /locus_tag="VWX64_000747"
     CDS             complement(38091..39005)
                     /locus_tag="VWX64_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU9190270.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LQDSPGTNNFSLPNVSPTYGQYYTNQSEVIIGKNDLVKVKNTLQYPYSTSAYVESEFR
                     GVKNGKDVTYRGSANFIKDNVLITAAHNIYKHEFGKDAEELYVTPARTPNSVPFGRIK
                     VKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLTGITVTITGY
                     PSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASNRVVGVHTLGDGAN
                     QINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(39155..39421)
                     /locus_tag="VWX64_000748"
                     /pseudo
     CDS             complement(39155..39421)
                     /locus_tag="VWX64_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(39446..39757)
                     /locus_tag="VWX64_000749"
     CDS             complement(39446..39757)
                     /locus_tag="VWX64_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU9190271.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(39682..39924)
                     /locus_tag="VWX64_000750"
     CDS             complement(39682..39924)
                     /locus_tag="VWX64_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU9190272.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(39925..40557)
                     /locus_tag="VWX64_000751"
     CDS             complement(39925..40557)
                     /locus_tag="VWX64_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9190273.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQATVYAFQHHLVGQEEF"
     gene            complement(40571..41566)
                     /locus_tag="VWX64_000752"
     CDS             complement(40571..41566)
                     /locus_tag="VWX64_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9190274.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(41563..42261)
                     /locus_tag="VWX64_000753"
     CDS             complement(41563..42261)
                     /locus_tag="VWX64_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU9190275.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(42339..43349)
                     /locus_tag="VWX64_000754"
     CDS             complement(42339..43349)
                     /locus_tag="VWX64_000754"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU9190276.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYIKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(43333..44340)
                     /locus_tag="VWX64_000755"
     CDS             complement(43333..44340)
                     /locus_tag="VWX64_000755"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU9190277.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(44327..45280)
                     /gene="mvaD"
                     /locus_tag="VWX64_000756"
     CDS             complement(44327..45280)
                     /gene="mvaD"
                     /locus_tag="VWX64_000756"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU9190278.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMAFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(45262..46140)
                     /gene="mvk"
                     /locus_tag="VWX64_000757"
     CDS             complement(45262..46140)
                     /gene="mvk"
                     /locus_tag="VWX64_000757"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU9190279.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVS
                     AESPWRLYEEDTLSMAVYASLEYLDITEACVRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETALSYGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(46262..46591)
                     /locus_tag="VWX64_000758"
     CDS             complement(46262..46591)
                     /locus_tag="VWX64_000758"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9190280.1"
                     /translation="MTRKVYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYFVN
                     YNGEWVQ"
BASE COUNT        13592 a        10778 c         8871 g        13477 t
ORIGIN      
        1 aaaagatacc gatttcattt actaaaaaag aaaaaagaac tgatttctca gtccttcatt
       61 aatcttattc cacactaaat aggtatgggt aaacaggttg ttgaccttgg tgaatctcga
      121 cttcaacgtc ttcgaattct tctacgattt cttgagcgat ttcattggca agttcttcgc
      181 ttccgtcttc accgacatag aaggttacga tttcactgtc ttcatccaac atatgtttca
      241 aggtttcagt caatgtttgg tgcatatcag ggtttgacac aagaattttt ccatccacca
      301 tacctagatt atcgttttca tggatttcta agccatcgat cgttgtatca cgcacggctg
      361 ttgtgacgct tccgctaaca acatcgctaa gagcagctgt catacgctct tggttttctt
      421 caatggactt gcttggatca aaggcaagaa gacttgtcat accttgagga agagtgcgag
      481 cctctaccac tactgctggt tgctccaaaa cttctgccgc agattgagct gccatgaaga
      541 tgttcttgtt gtttggcaag aagatgatgt tacgggcatt gacctgttca acagccttga
      601 taaagtcttc tgttgaaggg ttcatggttt gaccgccttc gataacataa tccacgcctt
      661 gagaacagaa gatatctgct agacctttac cagccaccac agcaatcaaa gcatactctt
      721 tttcttcagc cgacttgata acttgagtag cttctttctc aacctgtgct tcgtgttggt
      781 tacgcatatt gtcaactttt accttgacca agctaccata tttgagacct tcttgcataa
      841 caagtcctgg atcttctgta tgaacatgga ctttgacaat ttcatcatcg ttaacaacga
      901 ggagagaatc cccaagctca tccaagtagt tacggaattc atcgtagtca aaatctttag
      961 cataggttgg accttgctta agagctacca tgatttcagt acagtaacca aacgtgatgt
     1021 cctcagtcgc tacgtgacca gctacagact tatgatgctc tacattgatc atctcactca
     1081 tgttggcagg agtcgctaca aagtcctcag atgcaatata ttcgccagta agggctgaaa
     1141 ggaaaccttc gtagatgaag accaatcctt gaccacctga gtccacaacg ccaacttctt
     1201 tcaatactgg aagcatgtct ggtgttttag ctagagctgt tttagcacct tccaaggctg
     1261 cgcgcatgac ttcaacagcg tcatctgttt gctcagcttt tttcttagca ccgatagcag
     1321 ctccacgaga aactgttaaa atcgttcctt caacaggttt catcactgcc ttataggcaa
     1381 cttccacacc tgattggaag gccagagcca agtcttgacc tgttaactcg tctttatcct
     1441 tgatagcttg ggaaaatcca cggaaaagct gagacgtaat cactcctgag ttcccacgcg
     1501 cacccatcaa aagccctttg gcaagaatgc tcgctacttc tccaactgta gaagctggct
     1561 tgtctgcaac ttctttagca ccattttcaa tggtcattcc catatttgtc ccagtatctc
     1621 catctggaac tggaaagacg tttaatgaat tgacatattc agcttgctta ttcaagcgag
     1681 ttgatgcagc ctgcaccatt tcttgaaata agctagtagt aatttttgac acggttattc
     1741 tcctacaact ttgatatttt gaatgtagac atttacagtc tgagcagtaa ttccaagctg
     1801 gttttccaag ctaaaggcaa cacgctcttg aatgtttttt gacacttcac taatctttgt
     1861 tccgtagctt aacacggtat atacatcaac tgcaatactg ccatcttcgg ctgcctttac
     1921 gacgacacct ttagaataat tttccttacc tagcagggct tggaaattat ctttgagggc
     1981 atttttacta gccataccga ccacaccaaa aatctcagtt gctgctccac ctacgacggt
     2041 tgcaatcact tcatctgtta gttcgatttg accatctttt gtattaattt ttacagtcat
     2101 cctttttacc tcaactagtt gatactctat tttatcatat ttcagcccaa gtgtaaaagc
     2161 agaatgatgt atcagcggat atttactcta tttttcaaac gatgttatac ccacaataaa
     2221 agaaaaaaga ccctaaggtc tcctttgctt ttattattaa acgcgttcaa ctttacctga
     2281 tttcaaagca cgagctgaag cccaaacttt tttaggttta ccatcgataa gaacagtaac
     2341 tttttgaagg tttggtttta cggcacgttt tgtttggttc atcgcgtgtg aacggttgtt
     2401 tcctgataca gtcttacgac ctgtaaagta acatacttta gccattgtgt tttcctccta
     2461 ttagatctaa tatagcggat gtgctagcac cacataccgt actatgttat cacactttct
     2521 tgttttttgc aagggaattg gaagattttt tatttgtgtc ttaaatcagg tcttgcgtga
     2581 cattttctgc tctccacatg ccattgttga ttaacagaac accagaatta aaattatgtg
     2641 tataaaaatc atctctaact gcagctaagg gtatagccgt caagtccaaa tcccacagct
     2701 catctatcga ttttcttaca acaatatctg aatccaaata cagtacacga gactcgctta
     2761 catactttgg aataaaatac ctaaaaaaag ccgcatatga aagtccctca aaggggagac
     2821 gataaccttt cagaatacta ctgtcaatct gaacattcac aatctcacta ttcaaagtct
     2881 ctagtctttt ttccatcaat tggaaccatt ctcgcggaag gtcatcatta aaaacataaa
     2941 acttaagatt ataatgatga acacaaagag attttattgt tgtttcaact ttatccatat
     3001 aagcattatc tgcacctaag acaatcgctt ttttctcttc tttcactctt tatctcattt
     3061 ctttttattc ccatcatatg tttctacgta accattattt tcgcccattc gttcgtaaaa
     3121 ccataccagt ggagatttta gatgaagtcc cattacggtt tacaattttt acattacgac
     3181 acggagtttt acaaatcgat ttcatttgcc aaacgtagtt agtaaggcaa ttagctaggc
     3241 tacctacttt ctgctacgac ggaaaaatcc acaaatcaat accattcgtg gatttttcct
     3301 agtgaagcgt ttaggtaagc cgccatagcg gttaccgatt attagattac gacacggagt
     3361 ttggcaaatc gattctattt gccaaacgta gttagtgagg cagttagcta gttcgccaaa
     3421 tagcgactag cgtccaacaa tttggaactt tagttccaat tgttggtact gagtcacatc
     3481 ttctcctcta actctacgtc tggatacttg tccgcaaacc agcggagggc aaagtcattt
     3541 tcaaagagaa agactggttg gtcaaaacgg tctttggcta agatattgcg acttgacgac
     3601 atccgttcat ccaagtcctc aggcttgatc caacgaacgg tctttttacc cattggggtc
     3661 ataactactt ccgcattgta ctcgccttcc atgcggtgtt taaagacttc aaactggagt
     3721 tgacctacag cgcctagcat gtactcacct gtttggtaat tcttataaag ctgaacggct
     3781 ccttcttgca ccaattgctc aatccccttg tggaaggatt tttgcttcat aacattctta
     3841 gcagaaactt tcatgaaaat ttcaggagta aaggttggca ggggttcaaa ttcaaacttg
     3901 ttttttccaa ccgtcaaggt atccccaacc tgataagtac cggtatcgta aaccccgata
     3961 atatcacctg ccacggcatt ggtcacattc tcacgactct ccgccataaa ctgggtaaca
     4021 ttagatagtt tggccccctt accagtacga ggaagattga cactcatgcc acgctcaaat
     4081 tcgcctgata cgatacgaac aaaggcaata cggtcacggt gacgaggatc catgttggct
     4141 tggattttaa agacaaagcc tgagaaatcc ttgtcataag gatccacaat ttcaccgtct
     4201 gttttcttgt gaccatgtgg ttctggagca aacttgagga agatttcaag gaaggtctgc
     4261 acaccaaagt ttgtcagggc tgaaccgaaa aagacaggcg tcaattctcc agccagaata
     4321 gcttcctctg aaaactcatt cccagcttca tttaaaagct caatgtcatc cttgacttgc
     4381 tcgtagaaag gattgctacc aaaaagtttg tctccatctt ctaggctagc aaaacgctca
     4441 tcccctttat aaagttctaa acgttggtta tagaggtcat acaagccctc aaaggctttc
     4501 cccatcccga taggccagtt catagggtag ctagcaatgc ccaagatttc ttccaattct
     4561 tgcaagagtt ccaaaggctc acgaccgtca cggtccagct tgttcataaa ggtaaagact
     4621 ggaatgccac gatgtttcac aacctcaaac aatttcttgg tttgagcctc gatccccttg
     4681 gcagagtcca cgaccatgac cgcagcatcc accgccatca aggtacgata ggtatcttct
     4741 gagaagtcct cgtgccctgg cgtgtctaag atattcacgc gcttgccgtc gtagtcaaat
     4801 tgcataacag atgaagtaac agaaatccca cgttgcttct cgatatccat ccagtcagat
     4861 ttagcaaaag tccctgtttt cttccctttt accgtaccag cctcacgaat ctcaccccca
     4921 aagtagagta actgctcagt gatggttgtt ttccccgcgt ccgggtggga gataatggca
     4981 aaggtacgac gtttcttaat ttcttcttga atattcataa gttctctttc tttgattctc
     5041 tatttttctt gtttcaatag ctgagaatga tttttacatt ggattttacc attcctttca
     5101 acactccatt atatcggatt ttagcatttt tttcaatttc tatttctttt cacttccccc
     5161 tcccttattt ataggaaaat atggtaaaat agaacagact aaaaatcatc atttcacgaa
     5221 aggatgcaag atgaaaatta cgcaagaaga ggtaacacac gttgccaatc tttcaaaatt
     5281 aagattctct gaagaagaaa ctgctgcctt tgcgaccacc ttgtctaaga ttgttgacat
     5341 ggttgaattg ctgggcgaag ttgacacaac tggtgtcgca cctactacga ctatggctga
     5401 ccgcaagact gtactccgcc ctgatgtggc cgaagaagga atagaccgtg atcgcttgtt
     5461 taaaaacgta cctgaaaaag acaactacta tatcaaggtg ccagctatcc tagacgatgg
     5521 aggagatgcc taatgacttt taacaataaa actattgaag agttgcacaa tctccttgtc
     5581 tctaaggaaa tttctgcaac agaattgacc caagcaacac ttgaaaatat caagtctcgt
     5641 gaggaagccc tcaattcatt tgtcaccatc gctgaggagc aagctcttgt tcaagctaaa
     5701 gccattgatg aagctggaat tgatgctgac aatgtccttt caggaattcc acttgctgtt
     5761 aaggataaca tctctacaga cggtattctc acaactgctg cctcaaaaat gctctacaac
     5821 tatgagccaa tctttgatgc gacagctgtt gccaatgcaa aaaccaaggg catgattgtc
     5881 gttggaaaga ccaacatgaa cgaatttgct atgggtggtt ccggtgaaac ttcacactac
     5941 ggagcaacta aaaacgcttg ggaccacagc aaggttcctg gtgggtcatc aagtggttct
     6001 gccgcagctg tagcctcagg acaagttcgc ttgtcacttg gttctgatac tggtggttcc
     6061 atccgccaac ctgctgcctt caacggaatc gttggtctca aaccaaccta cggaacagtt
     6121 tcacgtttcg gtctcattgc ctttggtagc tcattagacc agattggacc ttttgctcct
     6181 actgttaagg aaaatgccct cttgctcaac gctattgcca gcgaagatgc taaagactct
     6241 acttctgctc ctgtccgcat cgccgacttt acttcaaaaa tcggccaaga cattaagggc
     6301 atgaaaattg ctttgcctaa ggaataccta ggcgaaggaa ttgatccaga ggttaaggaa
     6361 acaatcttaa acgcggccaa acactttgaa aaattgggtg ctatcgtcga agaagtcagc
     6421 cttcctcact ctaaatacgg tgttgccgtt tattacatca tcgcttcatc agaagcttca
     6481 tcaaacttgc aacgttttga cggtatccgt tacggctacc gcgcagaaga tgcgactaat
     6541 cttgatgaaa tctatgtaaa cagccgtagc caaggttttg gtgaagaagt gaagcgccgt
     6601 atcatgctgg gtactttcag tctttcatca ggttactacg atgcctacta caagaaggct
     6661 ggacaggtcc gtacacttat cattcaagat ttcgaaaaag tcttcgcgga ttacgatttg
     6721 attttgggtc caactgctcc aagtgttgcc tatgacttgg attctctcaa ccatgaccca
     6781 gttgccatgt acttagccga cctcttgacc atacctgtaa acttggcagg actgcctgga
     6841 atttcgattc ctgctggatt ctctcaaggt ctacctgtcg gactccaatt gattggtccc
     6901 aagtactctg aggaaaccat ttaccaagct gctgctgctt ttgaagcaac aacagactac
     6961 cacaaacaac aacccgtgat ttttggaggt gacaactaat gaactttgaa acagtcatcg
     7021 gacttgaagt ccacgtagag ctcaacacca attcaaaaat cttctcacct acttctgccc
     7081 actttggaaa tgaccaaaat gccaacacta acgtgattga ctggtctttc ccaggagttc
     7141 taccagttct caataaaggg gttgttgatg ccggtatcaa ggctgctctt gccctcaaca
     7201 tggacctcca caaaaaaatg cactttgacc gcaagaacta cttctaccct gataatccca
     7261 aagcctacca aatttctcag tttgatgagc caatcggtta taacggctgg attgaagtcg
     7321 agctagaaga cggtacgacc aagaaaattg gtatcgaacg cgcccactta gaggaagacg
     7381 ctggtaaaaa cacccacggt acagacggct actcttacgt tgaccttaac cgccaagggg
     7441 tacctttgat tgagattgta tctgaagccg atatgcgttc gccagaggag gcctatgctt
     7501 atctgacagc cctcaaggaa gttatccagt acgctggcat ttctgacgtt aagatggaag
     7561 aaggttctat gcgtgtggat gccaacatct cccttcgccc ttatggtcaa gaaaaattcg
     7621 gtaccaagac tgaattgaag aacctcaact ccttctcaaa cgttcgtaaa ggtcttgaat
     7681 acgaagtcca acgccaggct gaaattcttc gctcaggtgg tcaaatccgc caagaaacac
     7741 gccgttacga tgaagctaac aaaacaacca tcctcatgcg tgtcaaggaa ggggctgctg
     7801 actaccgcta cttcccagaa ccagacctac ccctctttga aatttctgac gagtggattg
     7861 aggaaatgag gactgagttg ccagagtttc caaaagaacg tcgtgcgcgt tatgtatctg
     7921 accttggttt atcagactac gatgctagtc agttgactgc taataaagtc acttctgact
     7981 tctttgaaaa agctgttgcc ctaggtggtg atgccaaaca agtctctaac tggctccaag
     8041 gggaagtcgc tcagttcttg aatgctgaag gtaaaacact ggaacaaatc gaattgacac
     8101 cagaaaactt ggttgaaatg attaccatca tcgaagacgg tactatttca tctaagattg
     8161 ccaagaaagt ctttgtccat ctagctaaaa atggcggtgg cgcgcgtgaa tacgtggaaa
     8221 aagcaggtat ggttcaaatt tcagatccag ctgttttgat tccaatcatc caccaagtct
     8281 ttgccgataa cgaagctgct gttgccgact tcaagtcagg caaacgtaac gccgacaagg
     8341 cctttacagg attccttatg aaggcaacca aaggccaagc caacccacaa gttgccctta
     8401 aactacttgc acaggaattg gcgaagttga aagaaaacta gatagaacaa aaccagccct
     8461 aaggttggtt ttttcttctc taccaactcc caataactat tttggcttta tttccagagt
     8521 attttatggt aaaatgaaga gtaataatat ttattaaaga ggtaaaaaca tgattgaagc
     8581 aagtaaatta aaagctggta tgacctttga aacagctgac ggcaaattga ttcgcgtttt
     8641 ggaagctagt caccacaaac caggtaaagg aaacacgatc atgcgtatga aattacgtga
     8701 tgtccgtact ggttctacat ttgacacaag ctaccgtcca gaggaaaaat ttgaacaagc
     8761 tattatcgag actgtcccag ctcaatactt gtacaaaatg gatgacacag catacttcat
     8821 gaatacagaa acttacgacc agtacgaaat ccctgtagtc aatgttgaaa acgaattgct
     8881 ttacatcctt gaaaactctg atgtgaaaat ccaattctac ggaactgaag tgatcggtgt
     8941 caccgttcct actactgttg agttgacagt tgctgaaact caaccatcta tcaaaggtgc
     9001 tactgttaca ggttctggca aaccagcaac gatggaaact ggacttgtcg taaacgttcc
     9061 agacttcatc gaagcaggac aaaaactcgt tatcaacact gcagaaggaa cttacgtttc
     9121 tcgtgcctaa tctctagaaa gaggtcattc tatgggaatt gaagaacaac ttggcgaaat
     9181 cgttatcgcc ccacgtgtac ttgaaaaaat cattgctatt gctactgcaa aggtagaggg
     9241 tgttcactct ttttcaaaca gatcagtgtc tgataccctt tcaaaacttt cactcggccg
     9301 tggcatttat cttaaaaacg tggacgaaga actcacagca gatatctatc tctaccttga
     9361 gtacggagta aaagttccta aggtagcggt tgctatccag aaagctgtca aagatgccgt
     9421 ccgtaatatg gctgatgtag aactcgctgc tatcaatatt cacgttgcag gtatcgtccc
     9481 agataaaaca ccaaaaccag aattgaaaga tctatttgac gaggacttcc tcaatgacta
     9541 gtccactatt agaatctaga cgccaactcc gtaaatgcgc ttttcaagct ctcatgagcc
     9601 ttgagttcgg tacggatgtc gaaactgctt gtcgtttcgc ctatactcat gatcgtgaag
     9661 atacggatgt acaacttcca gcctttttga tagacctcgt ttctggtgtt caagctaaaa
     9721 aggaagaact agataagcaa atcactcagc atttaaaagc aggttggacc attgaacgct
     9781 taacgctcgt ggagagaaac ctccttcgct tgggagtctt tgaaatcact tcatttgaca
     9841 ctcctcagct ggttgctgtt aatgaagcta tcgagcttgc aaaggacttc tccgatcaaa
     9901 aatctgcccg ttttatcaat ggactgctca gccagtttgt aacagaagaa caataaaaag
     9961 aaaaagtgtt tgatatctat caaacacttt ttctttgcct cccactatct aaaaaaatga
    10021 taatagatat aattgtaaac aaaaatccag ataggttttg catgattgag aaagttaaaa
    10081 aaactatggc agagaatcgt taatctcaga ttgtcggtag aacgataaac aagggcaaaa
    10141 aagaaaccaa tcagactata atataataaa ctaattggat ctctgtgaga tagtatcaaa
    10201 tggctaatcc caaagataag gcctgataag atgacatcta aatagtactt tgacttagga
    10261 aagaaggtat tcataaaata ccctctatca agagtctcct caaaaaaatg agcatagcgt
    10321 gcctaaaaat taccgagaat ctgataaacc acataagttg caaataagta gaagacaaat
    10381 gaccagttcc agctcttttt ttcaaagata aagagcatct ttttcttttt taacctccaa
    10441 attaatagaa ggaaacttcc cactaatacc attgttaaaa taagagaata gacatcagct
    10501 cctaacccta aaatgatcgt cacatacaat ccaattgttt gtggtaaata ggtagatagt
    10561 aaaataataa gcaaaaatat tccaaattgt cttagtttct ttgtgtttct catcgtactt
    10621 ttttgaaaga ttaccctgct cggaagccgt acttccaagc atctatataa gaattaagtg
    10681 ccccttgcct catataggga gcaaattctc tataatataa ccatctacta tatccatctt
    10741 cccaaacagc aagaccacct gaagtttgct ccaagtcctc agttgaaaga actgtaaatg
    10801 tatttgtacc tgtcattgca agtaccttct taaaatagat tgttgtaggc tcacatttat
    10861 agtatatttc tttttttgtc tattttatag cccatctcct caactggcaa tttttcgacc
    10921 tgaattgcat ttttccataa aaaatgagac ctttctagtc tcatttagtc attcttagta
    10981 ttttctaaat cgttgatagc gttcttccag caactcttct agcggttttt gtgaaagtct
    11041 agccagctcc gtttggagtt cttttttgac actcttaatc agttctttac tagaaagtcc
    11101 tacttcagaa atcaccttat ccaccacgtc catttctaac agttcatgcg aagtgatttt
    11161 catcagttct gctgcttcca tggcgcgagt accgtccttc cataaaatgg aagcaaagcc
    11221 ttctggactg agaatggcat agatagaatt ttccagcatc cagacacggt ccgcgacagc
    11281 tagagccaga gccccgcctg aaccaccttc accgataata atggcgataa taggaacttt
    11341 caggtcactc atttccatga gattgcgagc gatagcttcc ccttgaccac gttcttccgc
    11401 tccgacacca ggataagcac ctgctgtatt gataaaggtc acaactggac ggccaaattt
    11461 ctcagcctgt ttcatcaacc gcagtgcctt tcggtagcct tctggatgtg gttggccaaa
    11521 attccgtttg aggttgtctt gcaaactctt gcctttttgg ataccaacca ctgttacagc
    11581 ttggtctcca agccaaccaa taccaccaac aactgcacca tcatcacgaa aagaacggtc
    11641 accatgtaat tggataaatt catcaaaaat gcctgtcgca aagtccaagg ttgtcaagcg
    11701 actctgctca cgcgcttctc tgactatttt tgcaatattc atctaggact ccctccatgc
    11761 aatctgacta ggctagcaat cgtatctggt aagtctcttc ttttgacaat agcatccaca
    11821 aagccatgtt ctaataggaa ttctgccttt tggaaatcct caggcaagct ttcacgaacc
    11881 gtattttcaa tcacacgacg cccagcaaaa ccaaccaagc tctgtggttc agccagaatg
    11941 atatcgcctt ccatagcgaa agaagctgtc acaccaccag tcgttggatc tgtcaaaatg
    12001 gtcaggtaaa agagaccagc atttgaatgg cgtttaaccg ccgcagagat cttagccatc
    12061 tgcatgagac tcatgattcc ttcctgcata cgggctccac cagaggctgt gaataggaca
    12121 actggcaatt tttcgacagt cgcatactca aacaaacgag tgattttttc acctacaacc
    12181 gtacccatag aagccatgat aaagttagaa tccataatcc caagagccac agtctgacct
    12241 ttaataagag cagttcctgt cacaacggct tcatgcagac ctgttttttc acgcataaat
    12301 gccagtttct tttggtaacc agggaaatgc aagggatcct tgctttcaat ccctgtaaac
    12361 aattctttga aggttcccat atcaatcgtc aaagccaagc gttcttgggc agaaatacga
    12421 aaggtatagc tacagtgcgg acagatacgt tcacttccca gatccttctg atagatggta
    12481 tgcttacagc ctggacactg ggaaaataat tcatctggaa cctctggctt agcttgaggt
    12541 ttttccctaa ccgaacgatt gggattgatt cgaatatact tatctttttt actaaataga
    12601 gccattgatt ccccttttcg gtttaaactc ttaaagtcat tttattcttt ttcttgatat
    12661 ttaggtaaga aggtttccat caagaaggaa gtatcataat ccccagcaat gacattgcga
    12721 tctgaaatga ggtcaagctg gaaatctgca ttggtctgca ctccttcaat ctctaattca
    12781 tagagggcac gttgcatttt catcaaggcg tcaaaacgat tttcgccgtg tactatgatt
    12841 ttggcaatca tactatcata ataaggcgga atggtataac ctggataaac tgctgaatcc
    12901 acgcgcaagc caactccacc acttggcaga tagagattag taatcttacc tggacttgga
    12961 gcaaagttaa aggctgggtt ttctgcattg atacgacact cgatggcatg accgcgtagg
    13021 acaatatctt cttgcttaac agacaaaggc tgacctgccg caatgcaaat ctgttcctta
    13081 acgatatcaa cacctgaaac aaactctgtt actggatgtt ctacctgaac acgagtattc
    13141 atctccatga aatagaaatt gctacttgct tcatcaagaa gaaattcaat ggttcctgca
    13201 ttctcatagc caacaaactc tgccgctcga acagcagcag cacctatttc atgacgcagc
    13261 gtttttccga ttgcaatcga gggactttct tccaaaacct tttggttatt cctttgaaga
    13321 gaacaatccc gttcacccaa gtgaatcaca tgtccatgct catcacctag gatttgaacc
    13381 tcaatgtgcc gagctggata gataacccgt tctatgtaca tggcaccatt gccataattg
    13441 gccttggcct cactagaggc agtttcaaag gcagaaacga ggtcatctgg tttttcaacc
    13501 ttacgaatcc ctttaccacc tccacctgct gaagccttga gcataacagg atagccaatt
    13561 ttttcagcaa caatcaaagc ttcttcagag ttatgcactt ctccatctga acctggtata
    13621 acaggcacac ctgctttaat catctgagca cgcgcattga tcttatcccc catcatatcc
    13681 ataacatgac cagatggacc gataaacttg atacctactt cttcacacat ggtcgcaaat
    13741 ttggaatttt cactgagaaa tccaaaacca gggtgaatag cttctgcctc agtcaagact
    13801 gcagctgata gaactgcatt aatattgaga taagactctg ttgccttgcc aggaccaata
    13861 caaactgctt catctgccaa aagcgtatga agagcttcct tatcagcagt tgaataaacc
    13921 gctaccgtcg caatccccaa ttcacgtgcc gcacggataa tacgaaccgc aatttcacca
    13981 cgattggcaa ttaaaatttt tcgaaacatg gagaacctcc ttagttccca attgcaaaag
    14041 taaggatacc actggctgca agcttgccat ccacttcagc ctttgcttca accacagcta
    14101 tggtgccacg acgttttaca aaagtcgctg tcataaccaa ttggtcgcct ggtacaactt
    14161 gcttcttgaa cttaaccttg tccataccag cgtaaaagac cagttttcct ttattttcag
    14221 gttttgataa ctctaacaca ccagcagttt gcgccaaggc ttccataatc agaacacctg
    14281 gcataactgg gtattgagga aagtggccgt taaagaaagg ttcgttaatg gtcacatttt
    14341 tgatagcaac aatggtatcc tcgctcactt ccaagacacg gtccactaga agcataggat
    14401 aacggtgggg aagagcttct ttgattcctt gaatatcgat catttgatac gtaccaatcc
    14461 tttaccaaac tcaaccattt cttcgttaga gacgagaatt tccgttacca caccatcctt
    14521 aggagctggg atttcattca tgactttcat ggcttcgata attaccaatg tttgaccttt
    14581 tttgacacta tcaccaactg taacgaaggc aggtttatct ggtccagcag ccaagtaaac
    14641 cactccaaca agtggactct ctacaagatt tccctcagta gccacacttg cttcagctgg
    14701 agctggaact tcttctgcta cagtctctgc tggagcagat gtaggagcta ctggactcgg
    14761 tgttgctaga acgggtgctg gagcgacttg agttgcaact tcaggcacag gtctcgcttc
    14821 attcttgcta aactgcaact catccgtccc atttttataa gaaaattctc tcaaacttga
    14881 ctggtcaaat tgagtcatca agtctttaat atcgtttaaa ttcatactta tctattctcc
    14941 caacgtttga aagcaagaac tgcattgtgg cctccaaaac caaaagtatt tgaaatagcg
    15001 tatggaattt ctttctccaa gccttgtcca taaacgacat tagcttcgat ataatctgat
    15061 acttcacttg tcccagctgt cattggtaca aagttatggc gcatagcttc gatggtgacg
    15121 atagcttcta ctgcacccgc agcccccagc aaatgtcctg taaaagactt ggttgatgat
    15181 acaggtactt ccttaccaag aacagctacg atagcaccac tttctccttt ttcattggca
    15241 ggagttgacg ttccgtgagc attgacatag gctacttgct ctggagaaat ctcagcttct
    15301 tccaaggcta gtttgatggc cttgatagct ccctgacctt ctggatgtgg agaagtcatg
    15361 tggtaggcat cacaagtatt tccgtaacca accacttcag ccaggatagt agctccacgt
    15421 ttttcagcgt gttcaagact ttctaaaacc aacatccctg aaccttcacc cataacaaac
    15481 ccattgcgat ccttatcaaa tgggatcgaa gcacgagttg gatcctctgt agtagagaga
    15541 gctgttaagg cttggaaacc agcgatggca aaaggtgtga tagaagcttc tgttcctccc
    15601 accaacatca catcttggaa accaaactta atggagcgga aggcatcccc aatcgcatca
    15661 tttgatgaag agcaggcagt attgatagat ttacaaacac cgtttgcacc aaaacgcatg
    15721 gctacattcc cagaagccat atttggtaaa gcttttggaa gagtcattgg tttgacacgt
    15781 ttgggtcctt tttcatgaag gcgaagtacc tgatcttcaa tttccttgat tccaccaata
    15841 ccagatgcaa cgataacacc aaaacgatcc ctattaagag cctctacatc aagattggca
    15901 tgatttacag cctcttgggc tgcatacaag gcatataaag aatagttatc aaaacggttg
    15961 gtatcttttt ttacaaagta tttatcgaac ggaaaatctt ggatttctgc cgcattatgc
    16021 acatcaaagt cactatgatc aaattttgta atgccaccaa tgccgatttt cccagttgct
    16081 aaactattcc aaaattcttc tggtgtattt ccgattggag atgttactcc ataacctgtt
    16141 accactactc gatttagttt cattcttttc acctctagct ttcgctacat acttaagcca
    16201 ccatcaatgg caaccacttg accagttaga taatcttggc ctgctaaaaa tactgtcaaa
    16261 tctgcaacct gctctgcctg cccaaattct ttcatcggaa tctgagctag tgtagcttcc
    16321 ttaatcttat ctgataagat agctgtcata tcagactcaa tcattcctgg agcaatcaca
    16381 ttgactcgta tattccgact agcgacctcg cgtgccacag acttggtaaa gccaatcaag
    16441 ccagccttag aagcagcata gttagcttga ccaatattcc ccatcaaacc aacaacacta
    16501 gacatattaa tgatagcacc ttctctggct ttcatcatcg gtttcaagac tgattgtgtc
    16561 atattaaagg caccagtcag attgaccttg agcacttttt caaaatctgc ttctgtcatc
    16621 ttgagcataa gagtatcttg ggtaatccct gcattgttga ccaaaacatc tactgaaccc
    16681 agttctgcaa tagcttgatc aatcatacgc ttagcgtctg caaaatctga tacatctcct
    16741 gaaatgggaa ccaccttgat accatagttt gaaaactcag cgagcaattc ttctgagatt
    16801 gccccacgac tgtttaagac aatgttggct cctgcttgag caaacttgtg ggcgatggca
    16861 agaccaattc cacgactcga acctgtaata aagatatttt tatgttctag tttcattttt
    16921 ttcctttcaa aacttctact tattttagtc tatttttcta aaagtgctac taaactcgct
    16981 tgatcttcca catgagctaa gtgagcagtt tgatcaattt ttttaacaaa acctgacaag
    17041 actttccccg gtccaatctc gataaagttg cttatgcctg cttcttgcat gaccccaata
    17101 ctttcataga aacgaacggg ttccttgacc tgacgcgtca agagctgagc gatgtcctct
    17161 ttttgcatca cagcagcttc tgtattgccg actaggggac aagtaaaatc tgaaaaactt
    17221 acctgagcta gagtttcagc tagtttctgg ctagcaggct caaggagagc ggtgtgaaag
    17281 ggacctgaca ccttaagagg aatcaagcgt ttggcacctg cttcttgcaa aagttcaacc
    17341 gctcgatcaa ctgcaaccac ttctccagca atgacgattt gtgcaggtgt gttatagttg
    17401 gctggagtaa ccactccaag ttcagaagct ttttgacagg cttcttcaat gacctctact
    17461 ggcgtattga gaactgctac catcttgcca gagtcagcag gagccgcttc ttccatatag
    17521 gctccacgct tagctaccaa ggcaaccgca tcttcaaaat ccaaggcgcc gcttgccacc
    17581 aaggcagagt attctccaag agacaaacca gcaaccatat caggctgata gcccttttct
    17641 tgcaataaac ggtagatagc aaccgaagtc gctagaatgg ctggttgcgt atagcgggtc
    17701 tgattgagtt tgtcttcttc cgtatcgatg agataacgta aatcataacc gagcacctga
    17761 ctcgctcgat caatcgtttc tttgacaatc ggatactgat catagaaatc ccgtcccatc
    17821 cctagatact gggcaccttg accagcaaat aaaaaggctg ttttagtcat ttcttacaac
    17881 tcctgcccag cgagaggctt cttcttgaat tttcttagcg gctccgtaat acaaatcttt
    17941 taggatttct tcagctgttt cttctttaga aacaagccct gcgatttgac ctgccatgac
    18001 agagccaccc tccacatcac cgtgaacaac tgctttggct agggcacctg ctcccatttg
    18061 ttcaaagatt tctaaatcag gatcttcctg cttaaaggca tctttttcag ccagttcaaa
    18121 atctctagtc aactgatttt taatagcacg aacagcatga ccaaagtgct gagctgaaat
    18181 cgtagtgtca atatcccttg cttttaaaat tttctccttg tagtttggat gggcattcga
    18241 ctcttttgca actacaaacc gtgtccccac ctgtacagcc tctgcaccta gcataaagcc
    18301 agccgcagca ccttcaccat ccgcaattcc tcctgcagca ataacaggaa tagatacagc
    18361 tgtggctacc tgtcgcacca aggtcatggt tgttaattta ccgatatgcc ccccagcttc
    18421 cattccttct gcaataacag cgtctgcacc gattttttcc atgcgtttag ctaaagcgac
    18481 actaggaaca acaggaataa cgattatccc agcttcatgg aaacgttcca tatacttgct
    18541 tggatttcct gctcctgttg tgacaacttt aacaccttct tcaataacga gatccacgat
    18601 atcttccaca aagggagata agagcatgat gttgacccca aagggtttat cagtcaatga
    18661 tttgatttta tcaatattgg ccttgacaac ttctttcggg gcatttcccc caccgataat
    18721 tcctaatcct ccagccttgg aaacagcccc tgccaaatca ccatcagcaa cccaggccat
    18781 ccctccttgg aaaataggat agtcaatctt caataattct gtaatacgcg ttttcatagt
    18841 gcctccaacc ttccttgctt acgtaatagt tcgatttcac cataatttga cagtcaaact
    18901 attacctaaa caagagggag tgggtttctc cctactcctt ctactaatat tctgcttatt
    18961 ttgcttgctc ttcaacgtaa gcaaccaagt caccaactgt tttcaagtca ttttctgctt
    19021 cgatttggat atcaaaagca tcttcgattt ctgagattac ttggaacaag tccaatgaat
    19081 ctgcgtccaa atcatcaaaa gttgattcaa gtgttacttc tgatgcgtct tttccaagtt
    19141 cttcaacgat aatttcttgt actttttcaa atactgccat gataggactc ctttaaaata
    19201 aatagttttt tataacaatg tgttcaccac atgattacct aaattgtaag aatgagcgtg
    19261 ccccaggtca agcctccacc gaagcctgat agaagaacag tctggctacc atctaaaggg
    19321 atgagacctt gttctacaca ctctgaaagt aaaatcggga tactggctgc actggtattg
    19381 ccatattcca tcatattggc tggaagtttg gctcggtcaa caccaatttt tctagccatc
    19441 ttatccaaaa tacggtcatt ggcttgatga agtagcagat aatccaagtc tgtcacctct
    19501 ataggagatt catcaatagt ctgcttgata gacttggcta catctcgaat ggcaaaatca
    19561 aagactgtgc gtccatccat cttcaaaaat gaatctgcac tttcttgatc tgaaaatgga
    19621 gaatgcaaac ctgaatgccc ataagttaaa cactcgctgc gacttccatc gctattgaga
    19681 ctctcagcta agaaatgctc ttgctcgcta gcttctaaca agacaccacc agcaccatct
    19741 ccaaacaaca cagctgttga tcgatccgac caatcgactg ccttagagag ggtttcacta
    19801 ccaatcacca agcctttttg aaagcgacca gaagcgataa acttttcagc agttgaaaga
    19861 gcaaatacaa atccactgca agccgcggtt aagtcaaaag caaaggcttt attagcacca
    19921 atattagctt gaacacgagc agctgtagag ggcatcatcg aatctggagt aatggtagct
    19981 aggatgataa aatccagttc ttctcctgtt attccagctt ttgccatcag tttcttagca
    20041 acctctgtag ccaaatcact ggtagattct gttcttgaaa tatgcctttg tcgtattccc
    20101 gttcgacttg aaatccactc atcattggta tccataatct gagccaagtc gtgatttgta
    20161 accacttgct ctggcacata atgagcaacc tgacttattt ttgcaaaagc cattatttca
    20221 aatcctccaa aaattggtaa agattagtca agcctttacc catgacagca atttcttcct
    20281 cgctcatgcc atcaataatt ttttctacca tggccttgtg gaagcgttta tgcagcctat
    20341 gaatcaagcg acccttcttt gtcaaatgca gatgcaccac acgacgatcc tgttctgacc
    20401 gaactcgctc aatgtagccc ttacgctcta aattgttcaa acttgtcgta acagttccaa
    20461 gagttaccat caactctttt gacacttgac ttggagtcac atctggagcc ttaccgatga
    20521 catcaatcgt atgcatttct ttgatggaga tatccttaaa acgactacct ctcaagttca
    20581 cttcctcaat tacaaggaca ttgttaaata tagatgttaa atattcattg attcgttggt
    20641 agtccatttt tcatatccct ccttcttcaa aaaactttta caatcaaaac atttgacaga
    20701 aagaattata tcaaaattca aagaatgatg caagtatttt ttactttcct gtaaatttag
    20761 gtcttcttct ctccgaatga gctcgcactc cttctttgaa atcctctgtt tgagctaagg
    20821 atttctgtag gttcagttct aaagtagcgt aaccctgcca gtctttaaat tggctctccc
    20881 aaaccaactt cttaatggca gcataggaat tacttgaagc acgtcttaat tttttaagaa
    20941 gctgttctct cgtcttttca agtttttcag cttcagaaac gcggtaaacc aacccccatt
    21001 ctagggcttt ttctgccgtt aaagcctctc ctgtcatagc taattgagca gcacgcgtca
    21061 caccgatact gcggctcaag agatgaattc cccctgcatc tggagccaaa ccaacaccaa
    21121 caaaggcttg gataaactta gccttatccg tcgccaaaca gaaatctgcc gcaacagcca
    21181 tattcgctgc ggcacctgca acagcaccgt caacttccat taaaacaggt ttggctattt
    21241 gcttgatttt ataagaaatc gtattgacca actctgcgat ttttgtcaat gatggaatat
    21301 catcctcatc cactgcccgc ttcatctcta ccaaatctcc cccaactgag aagacctttc
    21361 cattggcatt gattaagata aaatgcacag ctggattttc ttctgccaaa gtcagagctt
    21421 ctaaaatctc ctcacacatg ggaatatgaa aaccatttgc gacctcagga cggttcaagg
    21481 taaggattgc caagtcctct tcaagctgat aaataatgtg ttccatcagg gctccttttt
    21541 attttataag cagtttatac tcttcgaaaa tctctttaaa ccgcgtcagc ttccatctgc
    21601 aacctcaaag cagtgctttg agcagtctgc ggctagcttc ctagtttgct ctttgatttt
    21661 cattgagtgt taaattattt cactgtcaaa gtatatcttt tttaggagca gaaagcaaga
    21721 aaaaatcgac tgaaagtgtc tcagccgata agaaaggctc gctttaggct agaaagcatc
    21781 ttattttctt cattgaaaaa agcctttctt tctgctataa tcgtataaaa tacttacttt
    21841 aggagttctt atgaaagttg ttaaatttgg aggtagttct cttgcctctg ctagtcaatt
    21901 agaaaaagtt ttaaacatcg tcaaaagcga ttcagagcgt cgttttgtag tcgtttctgc
    21961 acctggtaaa cgcaatgctg aagatactaa ggttacggat gccctgatta aatactaccg
    22021 cgactatgtt gcgggtaacg atattagcaa gagccaaagc tggattatcg accgctatgc
    22081 tgctatggtt agtgaattgg gactaaaacc agctgtgcta gaaaaaattt ctaaaagcat
    22141 tcacgccttg gccactcttc ctattgaaga aaatgaattt ctctacgata ctttcctagc
    22201 agccggtgaa aataacaatg ccaaattgat tgctgcctac tttaaccaaa atggtatcga
    22261 tgcacgctat atgcacccta gagaagctgg gattgtggtc acaagtgaac ctggtcacgc
    22321 tcgcatcatt ccatcaagtt atgacaagat tgaagaattg acaaacacca atgaagtcct
    22381 tgtcattcct ggtttctttg gtgtcactaa ggaaaatcaa atctgtactt tctcacgtgg
    22441 aggttctgat attacaggtt ctatcattgc tgctggtgtc aaagctgacc tctatgaaaa
    22501 ctttacggac gttgatggta tctttgcagc ccaccctggt attatccacc aaccacactc
    22561 gattcctgag ttgacctacc gtgaaatgcg cgagttggcc tatgcaggct tctcagtcct
    22621 tcatgacgag gctcttcttc ctgcctaccg tggaaaaatt cctctggtta tcaagaatac
    22681 caacaaccct gaccatccag gtactcgtat cgttctaaaa cacagtaatg atgaatttcc
    22741 agttgtggga attgctggtg actcaggctt tgtcagcatt aacatgtcga aatatctcat
    22801 gaaccgtgag gttggatttg gccgcaaggt tctgcaaatc ctggaagaac ttaacatcgg
    22861 ttgggaacat atgccaacag gtatcgacga cctttctatc attctccgtt ctcgcgaact
    22921 aactcccatc aaggaagaag aaatcctgcg tcagttggtt caaaagacta aagtagatca
    22981 tgcagaaatc gaacacgacc tttctatcat tatgattgtt ggtgaaaaaa tgaagagcca
    23041 catcggagtg actgctactg cgacacgcgc tctatctgaa aacaaaatca acatccagat
    23101 gatgtctcaa ggttctagtg aagtttctat catgtttgtt gtcaataaag accaagagaa
    23161 agcagcaatt aaagccctct acaatgcctt ttttggaaaa agtaaggaag actaagcatg
    23221 gcccaatcac ttaacaaaac agtactcctc agtacgacag gcacttccta cctctctatc
    23281 gctgggaaag ttgggaaatt ccttgtcgga gatcaggctt tggaatttta cccagatgtc
    23341 aatgtcgaac aatttatcca gattccttgg agccatatca atcagattgg agccaatgtc
    23401 actggacgca aaatcagccg ccacttcgaa gtctttacag acaaaggaaa attcctcttt
    23461 gcttcaaaag actcaggtgc cattctcaaa attgcacgcg aaaaactcgg caatgacaag
    23521 gtcgtcaaac ttccgaccct gattcagaca attagccaaa aatttaaaaa tctatttgca
    23581 aaaaagtaga aactttagta taatcatagc aacggataag taggttatct tcttctttca
    23641 gaaagtctgc gggtactgcg agcagatagg agggataggt gaaattctac cgttagtaac
    23701 aattacatac acaatcaagt gcacacctgt gaagttggat ggaaccgtgg ccctgccact
    23761 ccaacgtttt gtcaggcgtg cttttttcat aaaggagttc ttatgttaga tatcaaacgt
    23821 attcgtacag attttgaagc tgtcgcagaa aaattagcta cacgtggtgt agatgctgct
    23881 gtcttgaatg aaatgaaaga aatcgatgct aaacgtcgta acatcttggt caaggttgaa
    23941 actctcaaag cagaacgtaa cacagtttct gctgagattg cccaagctaa gcgcaacaag
    24001 gaaaatacag atgacaagat tgctgccatg caaaatctat ctgctgaggt taaagccttg
    24061 gatgctgaat tggcagaaat cgatgctaaa ttgacagaat ttacaacgac tcttccaaat
    24121 atcccagctg acagcgttcc tgttggggct gacgaagacg acaatgtgga agttcgccgt
    24181 tggggtactc cacgcgagtt tgacttcgaa cctaaagctc actgggatct cggtgaagac
    24241 cttggtatcc ttgactggga acgcggtggt aaggtaacag gcgctcgctt cctcttctat
    24301 aaaggcctcg gtgctcgttt ggaacgtgct atctacaact ttatgttgga tgaacatgga
    24361 aaagagggct atactgaagt catcacacct tacatagtca accatgattc tatgtttggt
    24421 actggtcagt atccaaaatt taaggaagat acttttgaac tcagcgatac caactttgtc
    24481 ttgattccaa ctgctgaagt tcctctgaca aactactacc gtgatgaaat cttagacggc
    24541 aaagatcttc caatctactt cactgctatg agtccgtcat tccgttctga ggctggttct
    24601 gccggtcgtg atacgcgtgg cttgatccgt ttgcatcaat tccacaaggt tgaaatggtc
    24661 aaatttgcca aaccagaaga atcttacgaa gaattggaaa aaatgacagc caacgctgaa
    24721 aacattcttc aaaaactcaa ccttccatac cgtgtcgttg ctctctctac tggagatatg
    24781 ggcttctcag ctacgaagac ttacgacttg gaagtgtgga ttccagcaca aaacaattac
    24841 cgtgaaatct caagctgttc aaacacagaa gatttccaag cccgtcgtgc ccaaatccgt
    24901 taccgtgatg aagcagatgg caaggtgaaa ctccttcata ccttgaacgg ttctggactt
    24961 gcagttggac gtacagtggc tgcaattctt gaaaattacc aaaatgaaga tggttctgtg
    25021 accatcccag aagcacttcg tccatacatg ggtggagctg aagtcatcaa accataaaaa
    25081 ataaggttta gctatttcta gctagacctt ttttcgtaac caaatcagat aagcacctag
    25141 tacaaagaat aaaatagtta ggcatataat ggtttcagcc aataccaggt aatccagaaa
    25201 tggaagtttc aaaattccct gagccatctt gagcgaggtc gctgtgataa tggttgggaa
    25261 agtgagggct gagaaggctg gttgaaaacc ttgttttaaa atgttgggca gacgagttaa
    25321 aacaaagaaa aagaaggatt gagaagccaa aatcatgaca atcaagaccc aagtcggcag
    25381 gctggttcct cctactcgaa ctagagaagc caagagtaga gagaaaggag cacagtagat
    25441 tccttcttgt ccaagcaagg ctagtgggag tggatgtttc tttaaatcgc tataaataag
    25501 gggatagaga tagaaggtca agagaaaacc aaaactcaag gtcgcatagg caatttcgat
    25561 aatacctacc agaggatagg tcaaggcagc cactgctatc cccacataga gaaccgtcca
    25621 acttggagtg gcatgaaccc tccgccctga acaagcaaac ttgatggtaa aaccagcaat
    25681 caaggtcaaa tccaagagaa atgaaaacca ccaaatccct tgtgctacca aaggaagata
    25741 agagaatacg cgaaagacat aggtcgataa aatcatccca gccataggaa aggttgccat
    25801 tcctgacaaa agagggggct tggtcaattc ttgcttggtt tctttccaat taaagagatg
    25861 cagaattaga aagtaaatcc ataaaaccaa accagtcaga ctaaaaagat gggatagaac
    25921 cggcaacgta tctaaaataa gatttccagc tcctgccaaa cctagcaaac aacctgaaaa
    25981 tactaagggg agttttttca tcctaacctc caataatcat gttagtttca gtataacata
    26041 aaagcgctta aatgaggatt taaaaaaacg aagtccgctt atttcagact tcattttact
    26101 cagatatgaa ttaggcataa ggttgcaatt ctggattaat tggtgtatta gctaagttgt
    26161 tggcatagtt acagaggatt gctaggctga caccaaaaac cacatccaag gcattttgtt
    26221 gagtgtagcc agcttctaaa aactcagaca aggcttcatc tcctacacga cccttggtat
    26281 tgataactgc caaggtaaac ttagctaggg tatccaattt aggatctgtt tcaattggag
    26341 tacgattgcg aagagcttga atcaagtcat cattcatctg gatttgtttg atggaaaagg
    26401 ctgtgtgacc tgcgacacag aaggcacaac cattggtcac ggctgccgtg atttgcacca
    26461 cttcacgctc aacgggtgtc aggctgttgc gacggtggat agatgagaca atttggtagg
    26521 cttctaaaac agtcggggca ttggccaaga gaccgattag gttgggaata tagccattgt
    26581 tgtctttttc tactgtttca agaatttctt tcacttctgc tggtgctgac tctactgtat
    26641 ggatagtaaa tgttgtcata agatacctct tttcttatta ttgacactaa tattattgga
    26701 aaatcttata aaatcctgat tcctaagttt atctaagata aagctttatt ctctcataag
    26761 attttcgttg ttatattagt ttatcacact tccaatcact tgcataatat atattatata
    26821 tcaggctgat aaaaattatt tataggcaaa aaaatcacac gagctgtgtg attccattat
    26881 ttgtcaaaat actttttagt ttcagcaata acgacttgcg acaagaccaa gagggcaatc
    26941 aagtttggca gagccatcaa ggcgttaacg atatctgcga taatccagac catatccaac
    27001 tcgataaatc ctcctaacaa gaccatgagc acaaaaacca cacggtagag ccagataaag
    27061 cgaaccccaa agaggaactc aaaacagcgt tctccgtaat agttccaacc tagaatcgtt
    27121 gtaaaggcaa aaagcacaag gaagatggtc aagagggcag gcccaaagtg tgaaaagact
    27181 gttgagaaag ctgactgagt caaggcaacc ccattcaagt caccactcca aactccagtt
    27241 accaagatgg tcaaaccagt tagagtacaa atgatgaggg tatcaataaa ggttcctgtc
    27301 atggaaatca aaccttgctc tactggttca tttgtcttgg cagctgcagc tgcaatagga
    27361 gcagaaccca gaccagattc gtttgaaaac acaccacgcg ccacaccatt ttgaatagcc
    27421 atccgaacgc tagcaccagc aaatccacct accgcagcaa ggggactaaa agctgaggta
    27481 aagactaaag cgattgtgcc agggattttt ccgatattaa agaaaataac tgtaagagtt
    27541 cctaagatat aaatgatggc cataaaagga acaacagtag ttgaaacctt agaaatagac
    27601 ttgagtccac caaagactgc aatcgctaca aagacagaca agacgagagc tgtgatggct
    27661 ggcgaaatcg tcgttgtatt ttggatagat tctgtaatcg agttgacttg ggtgaaggtt
    27721 ccgattccca agagagcaac caatactcct gctactgcaa acaaaacagc aagtggtcgc
    27781 cacttttctc ccatccctag aaggatataa tgcatgggac ctcccgctac tgcaccatgg
    27841 tcgtccttgg tgcggtattt gatggccaag agtccttccg catacttggt agccattcca
    27901 aagaaagccg ccatccacat ccaaaataga gctcctggtc caccaacctt gatagccgtc
    27961 gcaactccta tgatatttcc tgttccaaca gttgatgcca aggctgtaca cagagctgta
    28021 aaactggata catcaccatg tcccttatcc tggataaaaa taagctgaaa ggccttgggc
    28081 agacgcaaaa cctgcaagag tcctagccgc atggttaggt aaatccctgt tccgaccaat
    28141 aaaatcaaga ggggcggtcc ccaagcaaaa gcatcgattg atttaagcaa ttctaacatt
    28201 tccttctcct atcgtttcaa ccccaaaaga aagagcacat gcaagataca tgtactctgg
    28261 aatgcttaga taaatgctaa aaagcggtct atcctagctc tgtcctttta cctgagagtt
    28321 tgagcagttg cctgccttgc cccttcggtg cctttacggt ctctccagag ttccgtccat
    28381 ttacagtcat ggaaaatcaa acgattcccc acttctatta aacttcattc ggtgttggta
    28441 tttaattgat tctaatttta caaaaaatgt tggcttttgt caatgtgttt attagtaaaa
    28501 attagttcaa cagtttttac tttataaagt ccagaatact gctatccttt aaaagtgaca
    28561 atagtcgcac cactgcctcc agcattttgt ggggcatagc cgaaactctt gacatgtttg
    28621 tttctttgca agtatttggt aactccttca cggatgactc ctgttccgat accatggatg
    28681 atatcaactt gagccatatt gttaagcaag gcttggtcga tgaaggtatc tagctcattc
    28741 atggcttctt catagcgctt gcctcgaaga tccagtctag cttgaggtcc tcgcccagaa
    28801 gttcgtttca caacattgac ctgtttcttc ttgactggtt tttcttgctg ggcttgaaca
    28861 agatcaaact ctttctcttc caaggtcatc ttaatcaagc caacttgggc ttcccagcgg
    28921 ccgtccttga gttgactggt caaggtacca cgctgaccat aactgagaac cacgatatca
    28981 tctcccacct ttggagctcg ttttttcttg gccttttgaa ggaccttgtt tttagacaag
    29041 tccacttttt caggagccaa ttttttcaac ttggctttgg cttcaatgat ttcgtggggc
    29101 ttgagttggg atttactgtg gagatttttg agaatctggt cactttcact tagggccata
    29161 tccacaatct cagcagcctg ttcacgcgcc ttgttaagct cggtttcctt ttcacgatta
    29221 agctcgttgt agagtttttt tagcacacgg ttcatcttga gattttcttg ctccacctca
    29281 cggatattgt ccaagcgttt gcggctttcc agcgtctgct cttctagttg ctcaatgata
    29341 cgattgacgt cattgtcctg atcgatctgc tgactggcat ctcctacgat aacttcagat
    29401 aggcctagac gtttggcaat ttcaaaggca ttacttcggc caggaacacc ctgcataaag
    29461 cgataggtcg ggcgaagagt tgcagtatca aactccatac tggcattttg cacaaaggct
    29521 gtctcaatac cgtaggcctt gagttctgga tagtgggtcg tcgccatggt cttgatttga
    29581 cgcaggcgaa ggtcctccag aatagccatg gcaagggctg ctccctcttg gggatcagta
    29641 ccagccccca actcatccaa aagtaagagt gaatgttggt tgaccttgcc aagaatatcc
    29701 acgatattgg tcatatggct agagaaggta gacaagctct gctcaataga ctgctcatct
    29761 ccaatatcag caaagatttc ttcaaaaata ccaacacgac ttcccttgtc tgctaaaatc
    29821 ggcaatcctg actgggccat gacctgtgtc aagcccagag ttttgagcat gatggtcttc
    29881 ccacctgtat tgggacctgt aatgacaata gctgttaaat cttgaccaaa atagacatca
    29941 tttgcgacgg catttttgac caaaggatgg cagacatgga gcagttgaat ctcttgattt
    30001 tctgacagct gaggcacgac tgcttgtctt tcttggataa atcgaacctt ggcacgaatc
    30061 aagtccagat gaccgataat ccaagcgtca ttagcaatct cagccgcatg agggcggaca
    30121 cgctcagaaa tttcttggag aatgcgaagc atttcatagc gctcatctgc tcgcagacta
    30181 gcaatttctt cgctcagttt gactacctca cgtggttcga tatagacggt gtttccacta
    30241 gcagaaatat catgaacgac acctgcaatc ttattgcggt aggtgttttt gactggtaaa
    30301 acctgacggc catttctgct agcaacaatt ccttccgtca acatctgcgc tttttgcttg
    30361 agcaagtctt gtaaaacatc gcgtacctga ctctcgctat catgtatttt tcgacggatt
    30421 cgcgccaatt cttcactggc aaaattttca atgaaacccg catcattaaa ggcctgaaga
    30481 tttccttgta attgcggaaa atcatgtaat ttctcaaacc aaagggctaa ttcttccaag
    30541 ctgacatttt ccagattggc gtaaaaactt tgaagttctc ggctggtaag aagcacgcgt
    30601 ttcaagagta ggaactcctc gatattgaga tccgctccca tctccaacct cttgcagact
    30661 cctgcaattt ccttagttga gagaatagta aaatgcggtt gctcgacgaa aagagcctgc
    30721 atttctttca tctcagcaaa agcctgtttg attttatctg ctttggcagt cggagccagc
    30781 tgtctcaatt gctccaagcc ctgctcggtc aacaaatgag gctcaaacaa ggccttgacc
    30841 ttatcgaact ctaatgtttc taatattttc ttattcatct ttatttcctt gtctttgaat
    30901 gtctaggtgt ggtagctttt tacattctga tagattcgag tcaaatctgt aaacaaaggg
    30961 ctaggaaaac tcctgccctt tttatccgat taaatttgtc acccagattt gtttgagcca
    31021 actggttgtt atcggtatgc tctggatgat gtgttttgcg acgatactct tttcaagagg
    31081 attttgtata actgccatgg ggatggtcgc caagattgtc aaggccattt gcaagacaaa
    31141 taaggtcacc aacatggaca agatacctgc tgaaacttgg aacaacttac cacccagttt
    31201 tttgctagga atcaagtgta agagaagacc aagcaaacga ccaatgctat agacaatccc
    31261 aaatacaagc aagtagccga tacctgcata aaagacctta tccagctgaa agagttgatc
    31321 cgatgggaaa aagaaagtcc cctgaccttc ctgcgaattt gcataaggga gcaataaatg
    31381 gaattgctct ccaagcccct tataaaactg gccagccata aaagccgatg ccatggctga
    31441 aatcaggtaa taaacctgta agagcaggcc tctccgatag ccgatataaa atccccaaac
    31501 caagaccaat agaagaagga atgaaatcat aaggaatcct caatcttgct ctgttcttgc
    31561 ttacaagtca caagcttgtg acggagttct tctagctctt gctccttatc gtcaaattca
    31621 atctcacggc tgagctgagt tgataaacag ttgactgcca acaaaagagc gattgtttca
    31681 tcatctgcgc taggcatttg ttctttaatt gcttggtatt tttctgtcgc aaccttagcg
    31741 atttcctcca taaaaaggtt atcatgttcg cttgtcaagg ttaacgattt tttcccgaat
    31801 gtaaatttga atcgatttag atttgccata aaattcacct cacgatatta taccaaaatt
    31861 cgctaatttt gtcagttttt acaaatttta ctgcttttgt ggtacaatag aaactatggc
    31921 aagtatcaca ctcacaccaa gcgaaaagga tattcaggct tttcttgaac actatcaaac
    31981 cagtctggct cctagcaaga atccctatat ccgctacttt ttgaaactac ctcaagcaac
    32041 ggtttctatc tatacttctg gaaaaatctt gcttcagggt gaaggggctg aaaaatacgc
    32101 cagtttcttt ggctatcaag ctgtagagca aaccagcgga caaaatcttc ctttaattgg
    32161 gacagatgag gtgggaaatg gttcctactt tggtggactt gcagttgtgg ctgcctttgt
    32221 cacacctgac cagcacgact ttttacgaaa actcggtgtg ggggattcta agactctgac
    32281 cgaccaaaag atccgtcaga ttgctcctat tctcaaggaa aaaattcagc accaggcact
    32341 ccttctctca cccagcaagt acaacgaggt catcggagac cgctacaatg ctgtttcggt
    32401 taaggttgcc ctccataatc aggctatcta tctcctcctt caaaaaggtg ttcagcctga
    32461 gaaaattgtg attgatgcct ttaccagtgc taaaaattat gacaagtact tggcacaaga
    32521 ggccaatcgt ttcagcaatc ctatcagctt agaagaaaag gctgagggca aatacttgtc
    32581 tgtcgcagtt tcttctgtca ttgcgcgtga tctctttctg gaaaatcttg aaaatctggg
    32641 acgagaactg ggttatcagc ttccaagtgg agctggaacg gcttctgaca aggtggctag
    32701 ccagattttg caagcctatg gtatgcaggg actcaacttc tgcgccaaat tgcactttaa
    32761 aaacactgaa aaagcgaaaa aacgcttaga aaggtaagtt atgaattcat ttaaaaattt
    32821 cttaaaagag tggggactgt tcctcctaat tctgtcatta ctagctttaa gtcgtatctt
    32881 tttttggagc aatgttcgcg tagaaggaca ttccatggat ccgaccctag cggatggcga
    32941 aattctcttc gttgtaaaac accttcctat tgaccgtttt gatatcgtgg tggcccatga
    33001 ggaagatggc aataaggaca tcgtcaagcg cgtgattgga atgcctggcg acaccattcg
    33061 ttacgaaaat gataaactct acatcaatga caaagaaacg gacgagcctt atctagcaga
    33121 ctatatcaaa cgcttcaagg atgacaaact ccaaagcact tactcaggca agggctttga
    33181 aggaaataaa ggaactttct ttagaagtat cgctcaaaaa gcccaagcct tcacagttga
    33241 tgtcaactac aacaccaact ttagctttac tgttccagaa ggagaatacc ttctcctcgg
    33301 agatgaccgc ttggtttcga gcgacagccg ccacgtaggt accttcaaag caaaagatat
    33361 cacaggggaa gctaaattcc gcttctggcc aatcacccgt atcggaacat tttaagaaac
    33421 ctaagaggcc gagaatcacc aatctcagcc tcttcttcta tcgtgagaaa atgattggta
    33481 ctatctaaac ttaccagaac agaaacacct caactctcac ctattcatgc aaaggaattt
    33541 tatggaagtt tatttttcag gaactattga acggattatt tttgaaaatc ccagcaattt
    33601 ttatcgcatc ctcctcctag aaatcgacga tacggacgca gaggattttg atgattttga
    33661 aatcattgtc acaggaacca tggctgatgt aattgagggc gaagactata ctttttgggg
    33721 gcaaattgtc cagcactcca agtatggaga acaactgcaa atcagtcgtt atgatcgcgc
    33781 aaaaccaact agtaagggct tggtcaagta cttttcaagt agccatttca aggggattgg
    33841 tctcaagaca gctcagaaaa tcgtggatac ctatggcgaa aataccattg acgaaatttt
    33901 gcaacaccca gaaaagttag aaggcatcgc aggactctct gccaaaaatc gcgaggcttt
    33961 cgtctccact ctccgtctca actacggaac ggagatgatt ttggccaaac tagccaacta
    34021 cggcattccc aacaaactag cctttcagat tcaagacttt tacaaggaag aaacccttga
    34081 tgtggttgaa aattatccct accaactggt tgaggatatc aagggtttgg gctttaccat
    34141 tgctgaccaa ctagctgagg aactaggcat cgaaagtcag gctcctgaac gcttccgcgc
    34201 cggtctagtt cacagtcttt ttcagacctg tatggaaaca ggggacacct atgttgaagc
    34261 acgggatttg ctggaacaaa cccttactct ccttgagtct tcccgtcccg tggaactaga
    34321 ccccagccaa gttgcccaag agctctccta cctgatcgaa gaagacaagg ttcagcagat
    34381 tgataccaag atctttgaca acagcctctt tttcgctgag gaaggtatcc gcagtcactt
    34441 gattcgtatc cttgaaaaag gaaaacagaa gagccaagat ttagaaacta ttcaaaagca
    34501 tatcactact gtcgagcaag aactggggat tgagtatgat aacattcaaa aacaagctat
    34561 ttgtgacgct atccagaaca aggtctttat cctgacaggt gggcctggta ctggtaagac
    34621 aactgttatc aatggaatca tcgctgttta tgccctttta gaaggacttg acttcaggaa
    34681 gaaaaacaat ctgcccattc ttcttgctgc tccaactggt cgagctgctc gtcgcatgaa
    34741 tgaattgaca ggtttgccta gcgcgaccat acatcgccac ttgggaatga caggtgacga
    34801 tgataccagt catctggaag attacctaga tgctgacttt atcatcgtgg atgaattctc
    34861 tatggtggat acttggctgg ccaatcaact cttctccaat atctcttcta acagtaagat
    34921 cctcatcgta ggtgacagtg atcagctacc ttctgtcagt cctggacagg ttctagcgga
    34981 tctgcttcat attcctttga ttcctcagac tcgcttggaa aaaatttatc gacaaagcaa
    35041 agaatcaacc atcgtcaccc tagctagtca gattcgacag ggcatcttgc cagctgattt
    35101 cacccaaaaa aaagctgacc gttcctactt tgaaattgct agtggccata ttcctgccac
    35161 cattgaaaaa atcttaggtg ccgccctcag aaatggtatt cctgcccgtg atatccaagt
    35221 tctggctcct atgtaccgag ggacggcagg gattgatgct atcaatcagc tcatgcaaga
    35281 cctgctcaat cccccacaaa aagatcaact cagttttgaa gctcctcagt gccactatcg
    35341 taagagagac aaggtcattc atttggttaa cgatgctgaa atcaatgtct ttaatgggga
    35401 tttaggagct atcacagacc tgattcctgg taaatacacc gaatcgaaac aagacgagat
    35461 tgtcattgat tttgatggta atgaagtctc ttacccccgt aacgaatggt acaagattcg
    35521 cttggcctat gccatgagta ttcataagtc tcagggaagt gagttcccag ttgtcatcct
    35581 accgattact agtgctagcc gacgtatgct ggagcgaaat ctcatctaca cagccattac
    35641 acgtgccaaa agcaaactca tcttactagg cgaattacaa gccttcgact atgctaccca
    35701 acacatcgga actgcccgaa aaacctatct gattgaacgc ttcagtgatc tactggagaa
    35761 tgttgaagaa aagcaacaag ctgtctctga aacagtcaca tcaagtgcct ctgaacaatc
    35821 ctacatccta accgaagaaa actgggaccg catcccagcc atgattggga ttacagacac
    35881 agacctcaaa gagatttttg gaaaatagtg catcagaaaa cccaccaatt caggtgggtt
    35941 ttctgtttat taagattatt ttactgttgc tgtgcttgta atcaattcaa cagctttttt
    36001 gattgtgata tcatgtttca acatgtcagc tgaaagcaag ctttgtactt gagcaacttc
    36061 catgttgtag tctgctgcca attgctcaac ttctttttgg atttcttctt ctgaagcatc
    36121 aaatccttca gctttggcaa ctgcttcgat aacaaggtta gtcttagtac gtgactcagc
    36181 ttctgcttgg tattggttgt gaaggtcttc ttgagtagtt ccagtgattt ggaagtacat
    36241 gtcagggttg atcccttgac gttgcaagtt cccaaggaat tcatttactg aacggtgaac
    36301 ttcttcgtgg atcatttctt ctggaagttc tacgatttca gcattttcta cagctgtatc
    36361 aattgctgca ccttcaactg catctttgta agcttcttct ttagcagcag ccaattcttt
    36421 gcggtatttt tctttcaagt cagcaagtgt ttcaacttct tcatcaatgt cttttgcaag
    36481 ttcatcgtca agagctggaa cttctttagc ttttacttca tggatagttg tcacgaattt
    36541 agcttcttta cctgcaaggt cttctgcttg gtagtcttct gggaatgtta cgataacatc
    36601 aacggtttcg ccagctgagt gacctaccaa ttggtcttcg aaaccaggga tgaattgacc
    36661 tgaaccaagt ccaagtgaga agttttcacc ttttccgccg tcaaattcaa caccgtcgat
    36721 agaaccaacg aagtcgatca caacagtgtc gccgtcttca gcagcagctt ccttgataac
    36781 caattcagcc aggttgttgc gttcgcgttc gatacgctct tcgacatcag cgtcagttac
    36841 ttctttttct acatcaactg atacttcaag gtttttgtag tcacccaatt ttacttcagg
    36901 ttttgtaaca acttcagcag cgataaccca gtcttgacct ttttccattg aagttacgtc
    36961 aatttttggt tgggcaacca cttcaagacc agcttctttt acagctgctt cataagcgtt
    37021 tggcaaaaga gcgttcataa cgtcttggta aagtgattct tcaccaaatt ttttatcgaa
    37081 gataggacgt ggaaggtgac ctttacggaa acctggaaca ttaagagatt tcttcactga
    37141 cttgaagaca cggtccaatt ctggtttgat ttggtcttga gagatagtga aagtcaagac
    37201 accacggttt gtttctttgt tttcaaatga tacagacatt ctgtcatttc tccttaaaat
    37261 tttttaaata cagtctatta taacattttc tataaataaa atctagacta atgcagacaa
    37321 ttatagacaa caagcctttt tcctaactaa aacactcata aagtatagac aattttagac
    37381 tactttggat atcttttggt tagtcatttt ccaaaactaa tttatctaat ttttaagtta
    37441 tatttgactt catcttctca gtaacatgag tataaacact taaaatcttt gtttcattag
    37501 tataatctac acgatccatt atcgctatta taggtacttc caattcagca agcaaactta
    37561 tatgcgaata tctaaaaaca tgagcagtca atacaaaatc atctttctta atttcacttt
    37621 tcctaaacct gtttttcaaa aagtaattga aacaagttat cattaaggga gaaccattat
    37681 ttgtaaatat ataatcacct tcttctaaaa gaagatattc ttttaaaatt tctaacactc
    37741 tatcactaat accaattact ctatatgaag ctaaactttt cggactatcc aaaaacactt
    37801 cgttattgga cgattacatt atagtaaaac gaaataagaa caggacaaat cgatcaggac
    37861 agtcaaatca atttctaaca atgttttaga agtagatgtg tactattata gtttcaatct
    37921 actatacaag acgaaattga agaaatcttt ccattataaa acgcatatta tcaaggtttt
    37981 taaacaccta ataatatgcg ttttttccta ttttaaagac ttttatccac ctattataca
    38041 aagttaagta tccatcacag tttacaatta gccttcatta cctaacccat tcaccatcct
    38101 tcaagagagt aacctttaag aaccgaataa ataaatggca aatttcgttc atttaattta
    38161 actgcactgt taatttgatt agctccatct cctaaagtat gcactcctac tacgcggtta
    38221 ctagcatcat aaactgtaga tccactagac ccctctaaag tatcaacttg gtagtccaag
    38281 aacatgccat catcacttaa aacttgtttt ttatctgtat acatttgatg aattttaaaa
    38341 ttatatgatg gatagcctgt gatagtcaca gttattcctg tcaaattttt ttgactagta
    38401 ggaagaccca aagtccctaa ttttgcacca atgggctctt ctagaattaa taaagccaag
    38461 tcatattccc ttgcatcctt agaatttaaa tttctaaatt ccttcaaata acgaacttct
    38521 tttactttta tccgaccaaa cggcacacta tttggagtac gagcaggagt aacatatagt
    38581 tcttctgcat ctttaccaaa ctcatgttta taaatattat gagcagcagt aataaggaca
    38641 ttatccttta taaaattggc actccctcga taagttacat ctttaccatt tttcacacca
    38701 cgaaattctg actctacata agctgatgta gaataaggat attgtaaagt attttttacc
    38761 ttaactaaat catttttacc aataatgact tctgactgat ttgtataata ttgaccataa
    38821 gtcggtgaaa cattgggaag tgaaaaatta ttagttcctg gactatcttg taatgtctca
    38881 cttacctcat attcttcacc tgtactagaa ataacactca aagcagatac tgtcgataac
    38941 tggctagcca ataaagtact cgcaataatt gaaataccca attttttata aacagttttc
    39001 ttcattattg tatcctccta atgtaattat agcgtactat tctaaatttc ttaatctact
    39061 atagaatcaa gaaatctacc accttcttta aataccctcc attatcacat aaacaggtaa
    39121 acttttcaat taatgactgc gcttttcaat cacgctagag gtacttgctt gcttctttga
    39181 tactaagttc agccattctt tccttgtttt tctcaataaa gcatgttacc caagtgggat
    39241 tcgttttgga gtagtctcgc agagtccagc caatggcttt attgataaaa aattctgttt
    39301 ggttcaagtt atgaagtaga atcttttcca ttaattgagt attggtcttc tcttttctta
    39361 acaactggtg gtcaatagcg acacgtctca gccagatatt atctgatagg ctccatttta
    39421 tactcaatga aaatcaaaga gcaaactagg aagctagccg cagattgctc aaaacactgt
    39481 tttgaggttg cagatagagc tgacgtggtt tgaagagatt ttcgaagagt attaagatta
    39541 tttcttctag ttcagagtgt tcatacacca aactccctac tactcgatct aggatatcta
    39601 ccgtgtccca ccaggatttt gtcacgacta actgctctag cttaggcaaa tcggtttcct
    39661 ttagataaga ctgcattgct ttcaaatagt tagcagccac atattggtat tctctaggat
    39721 ccttttccca gcaagtgtct gcaaaatccc aatcgataat ctttgttttt ttcgcttctg
    39781 gaaaatattt ttatagagtt tatttctttc aggcaccgca atacctagaa aagaaaattg
    39841 atggcgcata taggcttcca tggaccttgc ttttttagag tcttttgctg cttctagctc
    39901 ctcaagtaaa tctgctaaac tcatctaaaa ctcctcttgc cccaccaaat ggtgctgaaa
    39961 ggcatagaca gtcgcctggg tacgatcgct gacttcaagt ttggcaagaa tattggacac
    40021 gtgggtcttg accgtcttga gagagataaa gaggtcatct gcgatgcgct gattttcgta
    40081 gcccttggcg atgagttgga gaacatctcg ctcacgcgca gtcaattctt catgaagttc
    40141 catatgattg cggtggtatt caaccttctt gctaacctct tgctcaatgg ccagctcgcc
    40201 agcagctacc ttactgacgg catgaagcaa ttcatctgca ctagaagtct tgagcatata
    40261 gcctttggca ccagcatcta agactggcat gattttttca ttgtccaaat aagaggtcac
    40321 aatcaaaatc ttggcttcag gccattcttt aaggattgct aaggtcgcgt caatcccatt
    40381 catctcaggc atgacaatat ccatgacaat gacatctgga cgcagttcca aggccaagtc
    40441 aatcccttga gacccgttgg acgcctcacc cacaacttct acatcgtctt ggaggtcaaa
    40501 gtagcttttc aagcccaatc ggaccatttc atggtcatct actagtaaaa ttttcatctt
    40561 tactccttta tcattcctta tctaacaggg gaatacggat atcaactgcc agcccttgct
    40621 tgggagctgt taataactga accgtccctg ccatatcttc aacccgctcc ttgatatttc
    40681 gcagtccata actcaagtcg tctaagctcc ctaaccggaa accaatccca ttgtccacca
    40741 ccttcagttg caattcaaca tctgtctgat agaggtagac atctaggcaa gatgcctggg
    40801 catggcggag cgtattgcta atcaactctt gcaggatacg gaagatatgc tcctcgattt
    40861 tcttaggcaa tttcgtcata ttctgcttga gactaaccct aagatcactc ttgtcctcaa
    40921 gctcttttaa gagaatctga atcccttcta tcaagctctt ctgctccagt tcaactggtc
    40981 gcaaatgcaa gagcaaaacc cgcaaatcct tctgggcagt ttctaaaata gctgtgacac
    41041 tctgcaactg gatctgcatc ttttctctat ccaatttcaa agcctgctga ctgatacccg
    41101 ataaaatcat gtgggccgca aacaactcct gactgactgt atcgtgcaaa tcccgagcaa
    41161 ttcgcttccg ttctttctcg atgatttcct cttcctgagc aaggctatga ttttcagctt
    41221 tttgaagagc ttctgtcaaa aggttaagtt tacctgataa ggacttgaaa ctggcatcca
    41281 aatctggatc tgcaacctga accacttctt gccctgccaa taaacgcttg agattagcct
    41341 gcatttttct tagagaaagc tcttcgatcc ctcgccaaaa cagggctaag agacaggtta
    41401 tggacatgct gaaaaccaac aataaaaaga caaatttttc tgttttttcg acatcgtgca
    41461 aaaagataga ccagtcaaaa tcaagtattt ccagcaagct gtgggagaaa aaaaagacaa
    41521 ataggaagga ggtgagagca ataatgacat aggcttgttt tttcatcctc taaccacctc
    41581 cacatcacca atcatagtgg tcaagaaaat cttgacactc ttgttactct tgagatagtc
    41641 ttttgtttct tgatgatagt gttcattgcg gagggctcgc ttgggctggt tgaaaaaagt
    41701 caaatcccca tagagacagt taacgctgag actgacttcc acatctacag gtacgatgat
    41761 tttggtcgtt cctaccatct ttctgaggat aatgacattg tcatgattgg ttaagatgac
    41821 cctctccaga tgaatagtgt ccttgcccat gaagcgaaag agattgatat catcgaattg
    41881 gcaagtctgg tagcttgaaa aatgatgaag atttccaaac caacgatttt tctccttctt
    41941 aaccgtcacg acctcttcaa aaaccaaatt ggtctgctct ttttcctggt tcatcatcgg
    42001 gtaaagaaga aagaggctat agataaccgc aacaaaaata gctagaatca caaaaggatt
    42061 gagcataacg atgaaaaaga agagaatggt tgccgctact aaaagaagat tatttccctc
    42121 tttaccagtg tagtagcgaa tcaaaagcaa aaagaggaat agtatcagca gaaaacgcga
    42181 aaaatgctct gataccatca aaatcagagc tcctgtcaga agacaggctt cgataaataa
    42241 aaagatttta aattttctca taggttcatc ctctcccttc tattttatca caattcaaaa
    42301 aagtcacctc agtctgagga tggaaaaaaa ggcgctggtt acgccttttt catctgatcc
    42361 tttgcttctt ttaattttcc ataaagaaga taatctactt tttgtagatc tgctatggtg
    42421 gcacagttaa gggaacacat aatcaagcgt agatctgctt tccagccttg gacaatgcca
    42481 atcacttctt caactgtgta ggtttcaacc aattccagaa cggttcgtga caatcccaca
    42541 gccttagcac caaaaaccaa gcacttaatc atatccagcg gattccgaac ccctccacta
    42601 accaagagtt cgaccttatc tttccattct tgggcattga gaagggcctg catggtagac
    42661 tgaccccatt gattgaggta atcacgctgg ccactacgac ggttttcgat ataggcaaag
    42721 ctggtgccac cacgacccga taggtccact gtacgaacac cgaattcata ggctctttcg
    42781 attgtcttgg catccattcc aaagcccact tccttgagga caataggaac gggaatttgc
    42841 ttgatataat ctgctaaatg cgattgccag cttctaaact tcctttctcc ctcgggcatg
    42901 agtaattcct gcatgacatt gacatgcact tgcaatagaa caggattcat ctcttctaca
    42961 gtctgaagtc ctaactcgac aggcttgtcc aatccaatat tggttccaag gaggagattg
    43021 ggatgactag acttgacaga aaaagaatca tccgttggat ttttgagggc tgcgctataa
    43081 gaacccgtta caaataaaat accacaggat tccgccacct gagccagctt ttgattgatt
    43141 tctcttccct tattacttcc accagtcatg gcattgatat aaaaaggaaa gtcccacttt
    43201 cgaccagcaa actctgtcga aagatcgatt tcatccagat tgtaaagagg caaggaagaa
    43261 tgaatcagct ccacctcatc aaagctatta taggaacttt tctgctcaag ggcatagagg
    43321 atatgctcgt ccttacgatt tgtcgtcatg tcctatcctt tcttgatata agagctcaat
    43381 ccccagatcg gcccaacgat tttttaaggt ttcggttgat tgcgcatcaa aactcagggc
    43441 gatgccacag tcaccaccac cagcaccact actcttggca acggcctgca aatcttgact
    43501 ggcttctttc aactgtctaa gcaaaggcgt gtaaatatct gtactcaagc cttctaaaag
    43561 cttgctggct acttctactt gctcgataac tttttcggct ttcccctgct ccaaggcttc
    43621 gaccaaagaa accaccgttt cttttgagga acttaaaaaa ttttgattga tattttgctt
    43681 gatttgctgg accatgtgac tcgatacagc cacttccttg gtccatccca ctaagaaatc
    43741 acattctaaa gttggtttca cttgtgagat aaaaaatccc caatcacgct ccagaactgt
    43801 cgccaagttt tcttcttcta accaagcagc cgccttctgg cgatcaaatg actggtagag
    43861 aaccaaatcc tctgccacaa tacaggcaag gtcgcccatg gaaccattgt ctcctcgctt
    43921 gagcaagaca gcgctagtca gcttgaacaa gagattctga tcaaccgaaa gattatagag
    43981 agccagtaaa gccttgacaa ccaagacaac gacgctgcca ctagaaccta gaccaaactt
    44041 tttcccttct cgttccattt tgccacagat ttttagggaa aaaggtctta aattctgacc
    44101 gcgaacagcg aggaagtctc ccatcaaagc aatcgtttct tgaatcaagc tgtagtcagg
    44161 attgggcctt aagtccactg cgaaatcaaa catatctgaa tagatacggt agctgtcaga
    44221 aaaagcaatc tcagccctca tatagatggg aatatccttt atcaaagcta actgccctgg
    44281 ctctaaaata gcatattcac ctgcccaata gagttttccg caagttttaa cagcaatcat
    44341 cttgactcaa atcctttgtt tttgacacaa tcaagcgata acgctgaccg aaaatttctg
    44401 acaaatgctc caagtctttc tcctgacaga agaccttaac attgggacca gcatccatgg
    44461 taaagtagca ggcctctcct ttctcacgaa gctggcgaac aaaggccata gcctcataag
    44521 aggcatccgt cagataagaa aaggctggac tagcagtctt tgtcgtagca tgcatagcca
    44581 gagcattttt ctccgttaat tctccaatct tggcaaaatc attttccttg agataaatca
    44641 gcatatcctg atagtccttc tcagactgac gaacccagtc gtcaaaagtc gtcgaggttt
    44701 ccacacaaag tttcatcccg tcacggctag agattggttt tttcttgtcc tctagcacca
    44761 acataatcat agctagtttc aagtctgtct ctacagggta aatttctcca ctatccttat
    44821 cccaggctcc tagtggtcca taaaaactcc gagaagaaga gcctgaggca aatttggctt
    44881 cctgtgccaa ctgacttcta tccaatccaa gcttgaaata agcattacaa gccttgacca
    44941 gggcggacaa accactagaa cttgaggaca ggcccgctgc cgtaggcata ttgttttgag
    45001 tatcgatacg gacaaagccc tcaccagctg gacgataacg gtcaataatc ttactcatct
    45061 tggcatgctc gacctcattt tgtagctgac cattgatgta aaattcgtca gctgttacat
    45121 tggctggtaa aggcgacaag gtcgtctctg tatacatatt ttccaaagtt agagaaatac
    45181 tgctagtagc aggcaccatc tctttttctt ttttctttcc ccaatatttg ataatagcaa
    45241 tatttgcgta ggaacgtact gttacaggct ctctatccat gtctgaacag ctcctttctc
    45301 ttctaatctt tctgctagtt cttgtgcgtg cgtcaaattg gttaccaagg ctatgataca
    45361 acctcctagc ccaccaccgc tcatcttggc acccagagca ccatagctaa gagccgtttc
    45421 aaccaaaaag tctgcctcag ggctactgac tccaatttct tttagatgta aatgcgcttg
    45481 actgaggatt tgtcccagtc cttcagcatc tttttgtgaa atcgcaactt ctgcttgctg
    45541 ggttaattct cccaaggcat gcaaaaacgg tagggcatcc ttgcccttat tttgaaccac
    45601 ttggatggct tcacgagtat gaccataaac acccgtatcg gcaatcacca aataggcgga
    45661 taaatccatc tcaagttctg taaatcctac gttcttgata aagcgaatag gttggtcact
    45721 gagacaggtc ttagcatcca aaccactagg attcatatgg gcaatcatct cagctcgatt
    45781 gaccaagatt tctagtacat catgaggcag atcagcctga tagtagtcaa ataccgcacg
    45841 aatggccgct atgctgatag ccgctgacga acccatcccc cgtttctcag ggatagccga
    45901 gtcaatctca caacgaacgc aggcttctgt gatatccaaa tactccagtg aggcataaac
    45961 cgccatggac aaggtatcct cctcataaag gcgccaagga ctctctgcag aaactacctt
    46021 acaggtcacc tccacctcca aaagaggcag ggaaatggca ggataaccgt aaacgaccgc
    46081 atgttcccct attaaaatta tcttactatg tgcctgaccg acaccaactt tttttgtcat
    46141 tttttccttt tactagacga aaaaacgtct tatttttcat acaagtatta attctttcct
    46201 atctatttta ttatattttc acaaaaaaag cgattgtttc cattcacaat cgcttctttc
    46261 attattgaac ccattcgcca ttataattga caaaatagcc atctacggtc gtattcactg
    46321 ccaaggcacc tgagctataa gcgtagtacc atctgccatt gacctggaac caacctgtcg
    46381 tcatagaacg acgaaagaaa ctccatacca ttaagtaaag aggaaagtcg tgagggagca
    46441 tgcgccattg acaacctgtt ttagtgacgt acaaagtctc attaacaagt actcgtttcg
    46501 gccatttata ggtgcggtgt ttggagaaat agggttcaat cttagcccat tcttgatcgt
    46561 ttaaatcagt atcatatact ttgcgtgtca taactctagt ttaacatttt ttgtgaatac
    46621 aggttctaaa taatcgacca cgaaaatttc ttaagtggaa aacgccttat gaagtatgct
    46681 acgggaaagt tatgcactta atttgacaat tcaagatg
//
LOCUS       DAVKBC010000012        45519 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVKBC010000012 DAVKBC010000000
VERSION     DAVKBC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.012"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(430..1158)
                     /locus_tag="VWX64_000759"
     CDS             complement(430..1158)
                     /locus_tag="VWX64_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9190281.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1316..2725
                     /locus_tag="VWX64_000760"
     CDS             1316..2725
                     /locus_tag="VWX64_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9190282.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTALTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2743..4038
                     /locus_tag="VWX64_000761"
     CDS             2743..4038
                     /locus_tag="VWX64_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9190283.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            4043..4351
                     /locus_tag="VWX64_000762"
     CDS             4043..4351
                     /locus_tag="VWX64_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9190284.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALEWIGEIR
                     "
     gene            4348..4656
                     /locus_tag="VWX64_000763"
     CDS             4348..4656
                     /locus_tag="VWX64_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9190285.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(5523..8174)
                     /gene="adhE"
                     /locus_tag="VWX64_000764"
                     /gene_synonym="adhC"
     CDS             complement(5523..8174)
                     /gene="adhE"
                     /locus_tag="VWX64_000764"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU9190286.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(8474..8884)
                     /locus_tag="VWX64_000765"
     CDS             complement(8474..8884)
                     /locus_tag="VWX64_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190287.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            complement(8886..9314)
                     /locus_tag="VWX64_000766"
     CDS             complement(8886..9314)
                     /locus_tag="VWX64_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU9190288.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            complement(9361..9660)
                     /gene="yajC"
                     /locus_tag="VWX64_000767"
     CDS             complement(9361..9660)
                     /gene="yajC"
                     /locus_tag="VWX64_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9190289.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            complement(9771..11753)
                     /gene="tkt"
                     /locus_tag="VWX64_000768"
     CDS             complement(9771..11753)
                     /gene="tkt"
                     /locus_tag="VWX64_000768"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9190290.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVAAAKEL
                     ASKGEKVRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLKQS"
     gene            complement(11867..12958)
                     /gene="ulaG"
                     /locus_tag="VWX64_000769"
     CDS             complement(11867..12958)
                     /gene="ulaG"
                     /locus_tag="VWX64_000769"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU9190291.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            complement(13070..14743)
                     /locus_tag="VWX64_000770"
     CDS             complement(13070..14743)
                     /locus_tag="VWX64_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9190292.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTLSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNESKSFSENLSSLISSYIVDSKLASKFQEEVQTFINQEIVVQAFLEDI"
     gene            complement(14920..15624)
                     /locus_tag="VWX64_000771"
     CDS             complement(14920..15624)
                     /locus_tag="VWX64_000771"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU9190293.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDFPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            complement(15626..16489)
                     /locus_tag="VWX64_000772"
     CDS             complement(15626..16489)
                     /locus_tag="VWX64_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU9190294.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIATLHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            complement(16493..17158)
                     /locus_tag="VWX64_000773"
     CDS             complement(16493..17158)
                     /locus_tag="VWX64_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU9190295.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIRR
                     IWG"
     gene            complement(17175..17660)
                     /locus_tag="VWX64_000774"
     CDS             complement(17175..17660)
                     /locus_tag="VWX64_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9190296.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGIAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELDDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            complement(17737..18018)
                     /locus_tag="VWX64_000775"
     CDS             complement(17737..18018)
                     /locus_tag="VWX64_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9190297.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            complement(18041..19498)
                     /locus_tag="VWX64_000776"
     CDS             complement(18041..19498)
                     /locus_tag="VWX64_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9190298.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            complement(19629..20252)
                     /locus_tag="VWX64_000777"
     CDS             complement(19629..20252)
                     /locus_tag="VWX64_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU9190299.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            complement(20303..21289)
                     /locus_tag="VWX64_000778"
     CDS             complement(20303..21289)
                     /locus_tag="VWX64_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU9190300.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            complement(21308..22132)
                     /locus_tag="VWX64_000779"
     CDS             complement(21308..22132)
                     /locus_tag="VWX64_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9190301.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNEVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGQFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            complement(22107..22478)
                     /gene="rnpA"
                     /locus_tag="VWX64_000780"
     CDS             complement(22107..22478)
                     /gene="rnpA"
                     /locus_tag="VWX64_000780"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU9190302.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYQEGNGSEKETKVD"
     gene            complement(22627..23817)
                     /locus_tag="VWX64_000781"
     CDS             complement(22627..23817)
                     /locus_tag="VWX64_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU9190303.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            complement(23868..24821)
                     /locus_tag="VWX64_000782"
     CDS             complement(23868..24821)
                     /locus_tag="VWX64_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9190304.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            complement(24882..25476)
                     /locus_tag="VWX64_000783"
                     /pseudo
     CDS             complement(24882..25476)
                     /locus_tag="VWX64_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            complement(25613..26026)
                     /locus_tag="VWX64_000784"
     CDS             complement(25613..26026)
                     /locus_tag="VWX64_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9190305.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            complement(26004..26465)
                     /locus_tag="VWX64_000785"
     CDS             complement(26004..26465)
                     /locus_tag="VWX64_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9190306.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            complement(26428..26688)
                     /locus_tag="VWX64_000786"
     CDS             complement(26428..26688)
                     /locus_tag="VWX64_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190307.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(26693..27097)
                     /locus_tag="VWX64_000787"
     CDS             complement(26693..27097)
                     /locus_tag="VWX64_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU9190308.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(27090..27416)
                     /gene="comGC"
                     /locus_tag="VWX64_000788"
     CDS             complement(27090..27416)
                     /gene="comGC"
                     /locus_tag="VWX64_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU9190309.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKEDGRITEEQAKAYKEYNDKNVGA
                     NRKVND"
     gene            complement(27418..28434)
                     /locus_tag="VWX64_000789"
     CDS             complement(27418..28434)
                     /locus_tag="VWX64_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU9190310.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(28382..29323)
                     /locus_tag="VWX64_000790"
     CDS             complement(28382..29323)
                     /locus_tag="VWX64_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU9190311.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(29399..29764)
                     /locus_tag="VWX64_000791"
     CDS             complement(29399..29764)
                     /locus_tag="VWX64_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU9190312.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(29915..30973)
                     /locus_tag="VWX64_000792"
     CDS             complement(29915..30973)
                     /locus_tag="VWX64_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU9190313.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(31136..32287)
                     /gene="nagA"
                     /locus_tag="VWX64_000793"
     CDS             complement(31136..32287)
                     /gene="nagA"
                     /locus_tag="VWX64_000793"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU9190314.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(32440..34257)
                     /locus_tag="VWX64_000794"
     CDS             complement(32440..34257)
                     /locus_tag="VWX64_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU9190315.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(34358..35500)
                     /gene="tgt"
                     /locus_tag="VWX64_000795"
     CDS             complement(34358..35500)
                     /gene="tgt"
                     /locus_tag="VWX64_000795"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU9190316.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            35630..36487
                     /locus_tag="VWX64_000796"
     CDS             35630..36487
                     /locus_tag="VWX64_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU9190317.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCHSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(36514..37131)
                     /locus_tag="VWX64_000797"
                     /pseudo
     CDS             complement(36514..37131)
                     /locus_tag="VWX64_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(37238..37597)
                     /locus_tag="VWX64_000798"
     CDS             complement(37238..37597)
                     /locus_tag="VWX64_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU9190318.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            complement(37608..38033)
                     /locus_tag="VWX64_000799"
     CDS             complement(37608..38033)
                     /locus_tag="VWX64_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU9190319.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(38356..39498)
                     /locus_tag="VWX64_000800"
     CDS             complement(38356..39498)
                     /locus_tag="VWX64_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9190320.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAEKQETQASPQAALAVEATTTS
                     SEAKEVASSNGATAAVSTYQSEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(39660..40283)
                     /locus_tag="VWX64_000801"
     CDS             complement(39660..40283)
                     /locus_tag="VWX64_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9190321.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFEAER"
     gene            complement(40287..41567)
                     /locus_tag="VWX64_000802"
     CDS             complement(40287..41567)
                     /locus_tag="VWX64_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9190322.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMILKG"
     gene            complement(41628..43112)
                     /locus_tag="VWX64_000803"
     CDS             complement(41628..43112)
                     /locus_tag="VWX64_000803"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU9190323.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAELMNTLNTQGQYELTDFDVEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQVAVEAYLGL"
     gene            complement(43188..44465)
                     /locus_tag="VWX64_000804"
     CDS             complement(43188..44465)
                     /locus_tag="VWX64_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU9190324.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(44572..44655)
                     /locus_tag="VWX64_000805"
     tRNA            complement(44572..44655)
                     /locus_tag="VWX64_000805"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(44619..44621),aa:Leu,seq:caa)
     gene            complement(44665..44736)
                     /locus_tag="VWX64_000806"
     tRNA            complement(44665..44736)
                     /locus_tag="VWX64_000806"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(44702..44704),aa:Gln,seq:ttg)
     gene            complement(44750..44822)
                     /locus_tag="VWX64_000807"
     tRNA            complement(44750..44822)
                     /locus_tag="VWX64_000807"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(44787..44789),aa:His,seq:gtg)
     gene            complement(44837..44907)
                     /locus_tag="VWX64_000808"
     tRNA            complement(44837..44907)
                     /locus_tag="VWX64_000808"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(44873..44875),aa:Trp,seq:cca)
     gene            complement(44912..44992)
                     /locus_tag="VWX64_000809"
     tRNA            complement(44912..44992)
                     /locus_tag="VWX64_000809"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(44956..44958),aa:Tyr,seq:gta)
     gene            complement(45005..45077)
                     /locus_tag="VWX64_000810"
     tRNA            complement(45005..45077)
                     /locus_tag="VWX64_000810"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45042..45044),aa:Phe,seq:gaa)
     gene            complement(45081..45154)
                     /locus_tag="VWX64_000811"
     tRNA            complement(45081..45154)
                     /locus_tag="VWX64_000811"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45118..45120),aa:Met,seq:cat)
     gene            complement(45165..45254)
                     /locus_tag="VWX64_000812"
     tRNA            complement(45165..45254)
                     /locus_tag="VWX64_000812"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45216..45218),aa:Ser,seq:tga)
     gene            complement(45337..45410)
                     /locus_tag="VWX64_000813"
     tRNA            complement(45337..45410)
                     /locus_tag="VWX64_000813"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45374..45376),aa:Ile,seq:gat)
     gene            complement(45445..45515)
                     /locus_tag="VWX64_000814"
     tRNA            complement(45445..45515)
                     /locus_tag="VWX64_000814"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45481..45483),aa:Gly,seq:tcc)
BASE COUNT        13532 a         9958 c         8185 g        13844 t
ORIGIN      
        1 taaaattttt ttaaatgatt atgattcaga atttatttaa tatattaaaa gaagatatga
       61 acaaataaat tgggagattg aaattcattt ctagcaattt gttagaagtc acagtctact
      121 attctaacct cagtatacta tatgtgttac aagaaaagac tcaaaaactt ctcgtcagtg
      181 taagaatgtt tgaaacacta tttaaaacta aataactata agaagtagat caggcgaaca
      241 atttcagtac ctactctata agctatacga agatattttt caacatgatg gataaaacga
      301 tcactctttt aaagccatct tatttagaaa agagaaacca tttaagcata gatgggacct
      361 tcttgccctg ttttaaattt ttcttaaact agagtctgta aaagattggc ttcattttca
      421 cattttctcc taggaggaat gtcgtaatgc aaaagaatta aattcaaata aatcatagcg
      481 atgacgacta atcgagtact caaacggagt tccgttatcc aaataagcca cttgttctac
      541 ttcaaatacc ggttccgttg gaaggagctg caagtaatgt tgctcatttt ctgaactaga
      601 agaagctcgt aagatttttg tagcactggc aatatgcaat cctaattttc cttcaatgta
      661 attgtaaatc gatttttgta aaatatcttc agtaatacct ggaataacat cggtactcat
      721 ataagtttgt tccagaacat aaggtttacc gtcaataata cgcaggcggt aaatattata
      781 aactggactc tgcaaagcga cctgtagttt ttctgctaaa aattcatttg caaattctaa
      841 tttgaagtga ataatcctcg agtcaattgt agaatgagca tcttcagata tttttgtcag
      901 tccccggata tctctttctg gaacgattaa ttttcttttt gagctgccac gagagagaac
      961 aaaggttccc tgcccacgtt ttctaaaaat taagccctca gaaactaaca agtctaaagc
     1021 ttttttgatc gtcattcgac tacaggcaaa ctgtttagct aatgtcattt catcaggcaa
     1081 ttgttcgttc atggtatatt tattacaaag aatcttttca cgaatctcat tgtaaataaa
     1141 taaatatttt gtactcattt aatctggttc tctctataat attctaatag tagtataaca
     1201 aagttcaaga aatgaggcaa acacaagata tgtatcaaca atttttaaaa atgtctagac
     1261 aaattttaaa attatgctat actttatgta tagaataata gaaaggaggt tgagcatgaa
     1321 aaaaaagtta gtatttccta atctgttttg gtggggagct gcttctagcg gacctcagac
     1381 agaaggtcaa tatggaaaag tacatgaaaa tgtgatggac tactggttca aaacgcatcc
     1441 agaagatttt ttcgataatg tcggacctct tgtagccagt aacttttttc atacttacac
     1501 cgaagatttc cacttgatga aggaaattgg agttaattct ttccgcactt ccatccaatg
     1561 gagtcgactc atcaagaatt tagagacagg tgagcctgat ccaaaaggta ttgctttcta
     1621 caatgccatc attgaagaag ctaaaaagaa ccagatggat cttgtgatga atttacatca
     1681 ttttgattta ccagtggaac ttcttcaaaa atacggtggt tgggaaagca aacatgtagt
     1741 ggagttattc gtgaagtttg ccaagactgc tttaacatgc tttggagata aggttcatta
     1801 ctggacaact ttcaatgagc caatggtcat tccagaagca ggatacttat atgctttcca
     1861 ttatccaaat ctaaaaggaa agggaaaaga ggccgtacaa gtcatctata atctaaacct
     1921 tgctagtgca aaagtgattc aactatatcg ctcattagga cttgatggaa agattgggat
     1981 tattttaaac ttgacacctg cttatccaag aagtaattct ccagaagact tagaagcaag
     2041 tcgatttaca gatgacttct ttaacaaagt cttcttgaat ccagctgtta aaggaacttt
     2101 cccagaaaga ttggtaaaac agctagagag agatggcgtg ttatggagtc ataccgaaaa
     2161 agagcttcaa ctgatgaaat caaatacggt tgattttctt ggagtaaact actaccatcc
     2221 aaaacgtgtt caagcacaag caaatcctga ggaatatcag acgccctgga tgccagacca
     2281 atacttcaaa gagtatgaat ggccggagcg tcgcatgaat ccatatcgtg gttgggaaat
     2341 ttttccgaaa gccatttatg atattgctat gattgtgaag gaagaatatg ataatattcc
     2401 atggtttatc agtgaaaacg gaatgggtgt tgaaaacgaa gcacggttta tcggtgaaaa
     2461 tggagttatc gatgacgtgt atcgtattga attttatgaa gaacatttaa gatggctaca
     2521 taaagccatt gaagagggaa gtcactgttt tggataccac gcttggaccg catttgattg
     2581 ctggtcttgg aataatgcat ataagaatcg ttacggattt atctccgttg atttagaaac
     2641 gcaaaagaga accatcaaga gctcaggaag atggtatcgc aaagtaagtg acaataacgg
     2701 ttttgaagta gaaattgagg agtaaagaga ggagatattc agatgaaaaa ctcaaaattt
     2761 atagatcaat ttgccacctt tgctggtaaa ctagggaacc aaattcattt aaaaactcta
     2821 agagatgcat tcgtaacagt aatgccatta tatattttgg caggtttaat cgttcttttg
     2881 aacaacacgg tatttaagtg gattttccaa ggggatacat taacaagatt ccaatattgg
     2941 ggaataacaa ttgcaaacgg tactttaagt atttcaggta tgattattgc tgtaatggtt
     3001 ggttatttct tagctaaaaa cagagatttc gaaaacccgt tagcagcatc aatgctatca
     3061 ttagtttctt taattgtgat gatgccaaat acagtttctg tagttcctga cggagcaaaa
     3121 gatgctgtaa acatttcagg tgttctttca ttcaacaaca caggtacagg cgcaatgttc
     3181 gccggggtta tcgtagcgat tattgcaaca gaattattca ttgaattatc aaatgttaaa
     3241 gctttacaaa tgaaccttgg tgaaaatatt ccaccagctg ttagtagatc atttagcgta
     3301 ttacttccag tcatgaccgt catctcctta tttggggttg tttcagcatt attattcaat
     3361 ataactggaa tgaacttaat ctcaatcatt acaatcttta ttcaagaacc aattcgtcat
     3421 attggtacaa gcttaatcgg ggtcattatt atttactctt taggaaatat gttatggcta
     3481 tttggtattc accaagcagt tatttacagt gccatcctag aaccattact attaattaac
     3541 attactgaaa acatcactgc agcaaataat ggacaagcca ttccacacat catcaaccta
     3601 tcacaaatac aaacattcgc tttaatgggt ggtagtggat ctacattatg tttattaata
     3661 gcaacattct tagtaagtcg caatgctgtt tctaaaaacg tggctaaatt atcttttgga
     3721 cctggtatct tcaatatcaa tgaaccagta ttattcggtt acccaatcgt ttataacatt
     3781 tcattagcta ttccatttat cacagttcca gtccttggta ttttaatcag ctacttagca
     3841 acagttacag gattcatgag tcctgcattt atacaagttc cttggactac accagtattc
     3901 ttaaatgcat ggttagcaac agcaggggac gtgagagcag ttctagttca attcatcatc
     3961 tttgcacttg gagttcttct atacattcca tttatcaaag ttaatgacaa agttgttgaa
     4021 caagaaatgg aaggttaaga ttatgaaaca aattttatta gtatgtaatg cgggaatgtc
     4081 gacaagtatg cttgttaaaa aaatgcaaca aagtgcgact gaacgtggga ttgaaatttc
     4141 tatccaagca aaatcaatga cagaagctaa aaagaatatc catgaagcag atgtcattct
     4201 aattgggcca caaattcgtt atgagttact tgctgtgaaa gaaattgcag gaaatatccc
     4261 tgtagatacc attgatatgc gggattacgg aatgatgaat ggagcaaaag ttctggaaca
     4321 agcacttgaa tggataggag aaataagatg acagaagaaa tggaatatat ctgttttcag
     4381 ctcattgcca atagtggagc agccaaatca tcctttattg aagccatcca actagctaag
     4441 gcaggaaatt taaaagaagc gaaaattaaa gttgaagaag cggaagactc cttagtagaa
     4501 gcgcacaaga ttcactctaa tctcatacaa aaagaagcta ctggagaaaa aataggattc
     4561 tccttgctat ttatgcatgc agaagaccaa atggcttcaa cagagattat tcagttgcta
     4621 tctaaagaat tcatcgatct ctatcaaaat aaataggaac actgtcattc ccatctgtct
     4681 ttattaatga cgactacatt gtaggaacct ccaaaagttg gacaaaatga ttgaaaggat
     4741 tggatcctgc attacacaag atccaatcct tttcttttac tctagttttt ataatatgtt
     4801 gaatctagaa tagtccactg tagtttctaa aaaattgctg gaaatggatg ttaagctcca
     4861 atttatttgt ttatatctta tttcagttta ctatactagc ttattattct agtgaaaaat
     4921 tgaatgagcc actatttatt taatatgtat gatgagggaa tgactcaaaa acttcttgtc
     4981 gatataagaa tatctgagat agtattttaa aacgaaagga ctataaaagc tcatttcctt
     5041 cgcacttatt ttatagagat ctatcattat actctttaga aatcaaaaag caacacacct
     5101 tgtcatcgtt ttatcgtaaa tctgttaatg agggggctag tcttatctgc aatctcaaat
     5161 cagtgttttg agctgaatgg cactcgtttt ctagtttgct ctttgatttt aattgggcct
     5221 tagtaaatac tactcttaaa ttaaactata gtgaattgaa ataagatgtg aacaactcta
     5281 tcaggaaagt aaaattaatt tctataaatg ttttagaagc agatgtgtac tattctagtt
     5341 tcaatctatt acatattttg tttctattct agtttttcaa aaagggcaaa aaggcctcaa
     5401 tatcataaaa aggcatccta tcaggtgttc aaaaaccttg ataggatgcc ttttatcata
     5461 gaaaaattac tggatctttc cctcaaattg agtttttgtc ttgcttctag actgataaac
     5521 aattatttac ggcgtcctgg tctttctttg tagccatagt atgcatcttc gatgatttct
     5581 tgcatatggt ctaccattgg aagacgtggg ttagctggtg aacattggtc ttcataagcc
     5641 aggaaggcta attcacgaga atgttctttc cattcttttt cgtcaattcc ttggtctcta
     5701 aaattcattt ggatcccaat acgttcaccg agttcgtaga cagcttttgc gtaagattca
     5761 accccttctt ctggagtaga agctggaagt ccaagcatgc gtgcgatatc ttggtatttt
     5821 tcatctgcac ggtagtagtt gtacttaggc catgttgctg tcttagctgg acgtgtaccg
     5881 ttgtaacgga taacgtatgg aagcaagata gcatttgtac gaccgtggat tgtgtggaat
     5941 tgcgcaccaa tcttatgggc cattgagtga gaaataccta ggaaggcatt ggcaaaggcc
     6001 ataccagcga ttgttgaagc gttatgcatt ttctcacgtg agtggaagtc agcattctta
     6061 actgagcttt cgagattttc aaagaccaat ttaatggctt gaagtgctaa accatcagtg
     6121 tagtcactag ccatttgtga tacgtatgct tctgtcgcgt gagtcaatac gtccatacca
     6181 gtatcagcag caacaaatcc tggaactgtc aataccaaag caggatctac gattgccaca
     6241 gttggtgtca atgagtagtc agcgattggg tatttacggt tgtttgcttt atcagagata
     6301 acggcaaatg gtgttacttc agatcctgta ccagatgtag ttggaatcgc gatgaattta
     6361 gtcttcttac caagcaatgg gaacttgaag gcacgtttac ggatatccat gaatttttgg
     6421 acaaggtcac ggaagtccac ttctggttgc tcgtagaaga gccacattac tttggcagca
     6481 tccattggag acccaccacc gagtgcgatg atggtatctg gtttgaaggc acgcataatc
     6541 tcagtaccac ggtttacagt tgtgatatct ggatccggtt ctacatccgc aaagatttgg
     6601 taaacaacct tattgcgacg aaggtccagt tgttcgatga tacgatcaag gaaaccaagc
     6661 tctaccatgg catggtcagt aacgatcatg acacgttcaa cgtcacgaca tttttgaagg
     6721 tattgaattg aatcacgttc aaagtatgtt tttgaaggaa gtttcatcca ttgcatgtta
     6781 tttctccgtc ttccgacttt tttgatattc aagaggttaa tggcactaac gttatcccca
     6841 actgagttgc gtccgtaaga accacatcca agtgtcaatg atggcaagaa ggcattgtaa
     6901 acgtccccga taccaccaaa agtagaaggt gagttacaga taacacgaat agctttaaca
     6961 gctttaccaa attctttagt caattcttcg tcagctgtgt ggatagctgc tgagtgtcca
     7021 agaccgttaa attcaaccat ttgacgagcc ttagtaatac catcttcacg gctttcagat
     7081 ttcaaaactg caataactgg tgacaatttt tcacgagtca atggctcatt ttcgccaact
     7141 tctttacatt ctgcagcaag aatgtttgtt ccttctggaa ctgtaaatcc tgcttgttct
     7201 gcaatccaag ttgctggttt accaacgatg tcagcgttca attttgcacc agcacagttt
     7261 ttgctgtttg ctttgacgcc gaagcagaac tcttcaagaa gagctttttc ttttttgttt
     7321 acaaagtaag tgtggtaaga tttgaactct gctacaaatt catcgtaaat ttctttatca
     7381 atgataactg cttgttcaga tgcacagacc ataccgttat caaatgattt agacatgacg
     7441 atatcgtgtg ctgcttgacg aatgtttgct gatttttcaa cataagctgg aacgtttccg
     7501 gcacctaccc caagagctgg tttaccacat gaataagccg ccttaaccat ggcattacca
     7561 cctgttgcaa ggattgtcgc aacaccttcg tggttcataa gggcacttgt tgcttccata
     7621 gatggttgag taatccattg cacacagttt tcaggagcac cagctgcgat agctgcatcg
     7681 cggacgatac gagctgcatg agcagatgat tcttgtgctg atggatggaa ggcaaagacg
     7741 attgggttac gtgtcttcaa tgaaatcaat gatttgaaga ttgctgttga tgttgggttt
     7801 gttgttggag taataccaca aacaacacca actggttcag caataagagt caatcctgtt
     7861 acatcgtctt cttcgataac gccaactgtc ttagtgtggc gcatgttgtt tactacgtgt
     7921 tcacaggcaa acaagttctt agttgcttta tcttcaaata caccacgtcc tgtttcttca
     7981 aaggcatgta aagccaattc tccgtgggca tccaaagctg ctactgatgc tttggcaacg
     8041 atgtagtcaa cttgctcttg atccaattta cgcatttctt caagggcaac tagagctttt
     8101 tgaaccaact catctacgtg tttttcagca acgagtttct tttcctctgg tgtcacagtt
     8161 tttttatcag ccatattttc ctccatagct ttcaaggaac gatatccttt gttaattttt
     8221 tcacaagttt attataacgc attatttcaa ctttgtaaac agtttcataa acatttcaca
     8281 aagaattttt aaactcttgt gaaacttttc tcattttctt ttcttatcag gttttatctt
     8341 tgaagtttgt gaaatttatt tcaaatattt tttatttcac aaacttgctt ggaagaggga
     8401 tttggaaaga aagggattta caggtaaacg cttaccttgt aattctaata atacctcctt
     8461 tgataaggag gctttatttt tgttgaaaaa cgccttgttt aaaagttcct tcataaacga
     8521 cttcttgttc tgttgttagt ttcccttttc cttcagcctg accatttaca aaatcacctt
     8581 cgtaggtcca gccttcttta gattgaaagg taccttttcc gttgaaggct ccattgttga
     8641 agccacctgt atattggtct ccattttgga aggtaatggt accttggcca ttcattttac
     8701 cacggacaag actgccatca taaacaatcg ttccattatc gagttttaag acaccttttc
     8761 ctggaatatt tagaaaaaag acgagtacag cacagaaaac aatggtaact actgccaaaa
     8821 gctctaaacg tggacgagtc agatagacac gatacttttc gtaaaaattc gtaagatttt
     8881 ccaccttaac tctccttttc taaacgttct aaccaagctt gacagccctc ttgaacacgt
     8941 cgataggttt cttcaaaatc tcctgtatac caagggtctg gaacactttc agatgaaaat
     9001 gagtaaatct tatcttgaca gtctactgga cacatctgac gtaagtcgga aacatttgaa
     9061 gcgtccattc cgataatata atcaaaggct tcaaaatctt ccttactaat ctgaagcgat
     9121 gtcttgttct tgtcataagg aatctcatac tcttgaaaaa ttccctgagt ccccttatga
     9181 atcggattgc catgttccca agaggaagtt gctcgacttt ggatttcgta gttatctgtc
     9241 attgatttca taacaaactc ggccataggg ctacggcaaa tatttcccag acagacaaag
     9301 actaattttt tcatcccatt tcctttcttt tatagaaaaa cgggagttcg tgatcccgtc
     9361 ttatttttca attgcgcctt ctagtgaagc tgtttctttc agcggtaata ctgtcttgat
     9421 agcagctagt tcaaaagtca agtaaactcc atctacgtca agaactattg ttcccttctc
     9481 cgtatctact tcatcgactg ttccataaag tccaccgatt gtaatcactt catagccttt
     9541 ttgtagttta tttaagcttt ccatacgttt ttgtgcttgt ttcttttgag agcgttgcat
     9601 aaagaacatc aaggccatca tacctacaag catgattaaa aaagtaatat ttggattcat
     9661 tgttttctcc tttgtctttt acataggact actatatcaa atttcagcta cttttacaag
     9721 attgtacctt acttttctgg taagaaaaac cagagcttac gccctgattt ttaggattgt
     9781 ttcaagtttc gaacaacttt tacaagattt tctacagtaa agccatattc tgccaatact
     9841 tttggtgctg gggcagaggc tccgaaggta tcaataccta gaacggcacc atcgagacca
     9901 acatatttgt accagttttg acttgcaccc atttcgactg caacacgacg gcggactgca
     9961 tttggaagaa tctcttcctt gtaagctgca tcttgtttat caaagacatc tgtagatggc
    10021 atgctgacta cgcggacttt ttcgccttta ctagctaatt ctttggcagc tgcgacagct
    10081 agattgacct ctgaacctgt cgcaatcaag atggtatcaa agtcggctgc attttcatat
    10141 acaacataag cacctttagc aaccttgtcg aagtctgttc catcttcaac agtcaagttt
    10201 tgacgtgtca agacaagggc agttggtgtt ttctcacttg tcactgcaag gtaccaagct
    10261 gcttgcgttt cacgcgcatc tgctggacgg aaaacattta gatttggcat agcacgaaga
    10321 cctgctaaat gctcaactgg ttcgtgagtc ggaccatctt ccccaactgc gattgaatca
    10381 tgggtaaaga cataagtcac aggaagtcct tgtaaggctg acaagcggac agctgccttc
    10441 acatagtcag agaagacgaa gaaagttcca ccgtatacac gaagtccacc atgaagggcc
    10501 atcccgttca agattgttcc cattgcaaat tcacgaacac caaactgaat gttacgattc
    10561 aagcgattgg tatcgtcttg aagtccatcc gtcttgatat aagtcatgtt tgagtgagca
    10621 aggtcagctg atccacctag gaaggttggt aatttagctg ccacaacatt caaggcatct
    10681 tgacttgaat tacgagttgc ttgagaaaaa ccattttcta aagctgggaa gtctgctgga
    10741 gtcacttcga ctggatcacg tccgtcgatg atggcctcta cttctgcagc cagttctgga
    10801 tgagcttctt tataatctgc aactaattta gtccaagctt gataagctga tgcgccacgg
    10861 tctgcaacat gttctttgaa atcagcatat acttgttctg gaatttcaaa tggttcgtag
    10921 tcccaaccga gggcttggcg agttgatgca gtttcatctg ctccaagagg ggcgccgtgt
    10981 acagcattag ttccttgttt gtttggagaa ccgtatccaa taaccgtctt cacttcaatc
    11041 aaagatggct tgcctgaagc ttttgctgtt tcgatagcag catggatggc ttccaagtct
    11101 gttccatttt caaccaaggc agtatgccaa ccgtaggcat tgtaacggtc acgaacactt
    11161 tctgtaaagg aatcctttgt ctcaccatcc aagttgatat catttgaatc ataaagaaca
    11221 accaacttat caagtttttg caagcctgcg tatgaagctg cctcgcttga gacaccttcc
    11281 atcaagtctc cgtctccaca gataacgtaa gtatagtggt caaagatatt gtagccttca
    11341 cggttatatt tggctgccaa gaaacgttct gcttgggcaa aaccagtagc agttgaaatc
    11401 ccttgcccta gaggacctgt cgtagcatca atccctgccg tatgaccaaa ttctgggtga
    11461 cctggtgttt ttgaacccca ttgacggaag ctcttaatct catccatgct gacatcttca
    11521 aaaccagaaa ggtgaagaag agcataaagg agcattgaac catgacctgc tgaaagaata
    11581 aagcggtcgc ggttaatcca gtttggttga gctggattga tatgaagttg ttttgtaaag
    11641 aggctgtaag ccatcggagc cgctcccata accacacctg gatgacctga gttggcttta
    11701 ttaatggcgt caatacctag aaaacgaatt gcattaacag atagatttga catagaattt
    11761 cctttctatt tgaggtgatt attgaatcac acattctatt ttactattat atgaaaatta
    11821 tccgtatcat gcaacatacg gataacctcc aaagaatatt tttatattat agcaaagctt
    11881 taaattgaat gttagagtct tgttcaaaac aatcatcaaa accacgtgga tgatggtatt
    11941 ctactaagtg ttgatcttga ggataagtgt acttaccgcc aacttcccag ataaatggat
    12001 ggaaatcgta ttgcaagcga tcttttcgca ttttccaaag ttctagaatc tcattagtag
    12061 aagccatgaa gttagaccag atatcatagt gaactgggat aatgactttg gtacgcagat
    12121 tttctgccat acgaagaagg tcgatagatg tcattttgtc ttggatacct accggatttt
    12181 caccatagtt attcaaagca acatcaattt taaagtcttt accatgtttt gcaaaatagt
    12241 ttgagaagtg agaatctgca ccatgataga tggttccacc tggtgtttca aagatatagt
    12301 taacagcctt ttgagccatt tcttcatctg taacagccaa gccagcaagt tcaccgcctg
    12361 tctcatcagc accgttcact gggagagtta ccaagcaagt acggtcaaat gattctactg
    12421 catgaatctt catatctttt aattcgatag tgtcacctgg tttaacaacg atgatacgtt
    12481 cttttggaac accccatcct tcccagattc gtccacagtg gtaaggaccg ataaacttaa
    12541 catgctctaa cttaggattg ttgagaattg ctgcagctgt gtatgggtcg atatgatcac
    12601 tgtggaagtg tgaaactaag taatagtcta gttcgttgat agcaaatgga tcgataacca
    12661 ttggctgaac acgcaagttt ggttgcagct tacgaacacc tgccatattt gccatttggt
    12721 gcccacgaac catatctttc acttttttgg ttgattttcc acggtttgac caaaggtcca
    12781 tgacaacgtt agcaccagct ggtgtcttaa tccaagtacc acagttgcct agccaccaca
    12841 tggcaaagtt gccttcaggt acgacttctt cttcgatttc ttcgttcaac catgttcccc
    12901 actctgggaa agtggctaaa atccatgact ctcttgtaat ttctttgacg tttggcatat
    12961 gttgcctcct ttggatataa ttgttatctt tgagattagt ataccaccct tcaaaacact
    13021 aaaaaagacc aagaaaaaca caggtttgtg ttcatcattg gactgtcctt caaatatctt
    13081 ccaaaaaagc ttgaactact atttcttgat ttataaatgt ttgaacctct tcttggaact
    13141 tactagccaa cttgctatct acaatataag acgaaataag actagaaaga ttttcactga
    13201 aacttttgct ctcattacga aatatattgt gtttaagata gtctagcatt ttcaaaatat
    13261 cttctgcttc aaggatagga ttaaccctta aaatcggaaa tctgctatcc aaatcatcat
    13321 tagtagtaat cactacatca acttgtgcaa tatcttccac actcttaaat tgttctgttg
    13381 taaatacagt gtcaatttgc tcatttggaa aataaagttt gcattgtttc agcaaaagtc
    13441 tcgaaaccgc aacaccttca tcacaaacga gataaacttt tttcatattt ttttgagacg
    13501 atagtgtata ctttaaaaat cctccaatat gaatcgtcaa ataggcaata tcatcgtctg
    13561 ttagccgaat aaaccatgct ccttctaaaa tttccgcaga ttttctagtg actaaaaata
    13621 attctccata cttggatcga atttgttttg ttagaggatt tttagaaaaa ataccgtaag
    13681 tctttctaaa taacaaggct ttacagtgga tcatcaaatt tcgtaacaaa tcatccttgt
    13741 tctcaatctc cattcggatt tgtgattcaa aataccagat aaattcttct aaagcaagtt
    13801 ttaattgccg aaaatcatca ctttctgcat gaatatccaa atctttacga taggagagga
    13861 ggagaacagc tacaagagaa acttcaagtc ctgacaaaga aatttcaaac ttttgaaaca
    13921 accgttctcc taatttctta gacacctgat actctattct ttttcttatc aaagaaaatt
    13981 ctttctctat atcctgatgt ctttcttgat actgttcaac attatgacag cttaacagca
    14041 aataaggtag aacctgcaac ataaaagtta tttcatgatg gtttattttc ttccctaaat
    14101 cttgttcaac taaaggaacc tgttccttaa aaaattggtt catttcaaca gaaagcaaac
    14161 actcatcatc taacctctct ttcatcttat cttctaaaat agatacaaaa gtggcatttt
    14221 cttccataaa aatatgatat agaagcgatt gaagatactg aattttatta agagggtggg
    14281 catgaaggtg gtatccctgt gacttgctca cttgcaaggt cacctgatat tgttccaaag
    14341 ttagttgata acgaatacta ttcaaatcat tgagaacagt attcctagat acctctgtta
    14401 actctatcaa tttttcaata gtaatacgtt ctttagaaat acctatccat agtaacatta
    14461 tcatcatacg ttcatgcgca ctcatgatat aatcgtacga atctacttcc gataatagtt
    14521 tacaacaagc atctctctgc tcttccgtta agtgaatacc aattcgtgga atactaatga
    14581 tgtgaagcgc ctcgtcaacc agagcagcat tgattttgtc aatgtgataa taaattttcc
    14641 ttcttgactc tttcaaatct ttcgaaatcg ccataatcgt tttggacgtt tcttgatcca
    14701 tcaaatattg aagcaaatca caacttgcct tatccagtac catattaaaa aatcccccaa
    14761 atctattgat atcacagcaa ttctttttat tttaccatat atatcaagcg ctatttctaa
    14821 aaaatctttc aaaattactt caactccaac tttactctca ataaaaatca aatgtaaaaa
    14881 gaggagctaa atttatcttt ttctcctcct tcatcgttct tacttttgac cataataagc
    14941 atttggtcca tgtttacgtt ggtagtgttt ttctagtatg tactggggag caggttcaac
    15001 tcttggattg atttgttctg taaagcgatt catctttgat acttcctcta gtacgacaga
    15061 gtgataaaca gcattctctg gatttttgcc ccaggtgaat ggaccgtgat tgcgtacaac
    15121 aattcctggt acttcaaccg ggttaagtcc gcgatgttca aactcttcta cgataaccag
    15181 gccagtatct ttttcatagg ccacttctac ttcgtccttg gtcaaactac gggcgcaagg
    15241 gattgaaccg tagaaataat ctgcatgggt tgttccgtag aaaggaatat cacgacctgc
    15301 ctgagcccaa gcaacagctt ctgtcgaatg ggtgtgaacc acactaccaa tttctgacca
    15361 agccttatat aattgcacat gagttgggaa gtcggaagat ggtcttaaat ccccttctag
    15421 gatcttacca tctagatcag tcactaccat gttttcaggt gtcaattcgt cataatccac
    15481 gcctgatggt ttgataacaa tgacaccgag ttcgcgattg acttcagata cattccccca
    15541 ggtaaatttg acaagtccat gttttggcaa tgattgattg gcatcacaga ctcgtttacg
    15601 catagcattg attacttgat tcatcttaca tcaaacctgc tttcttaatg agtggataga
    15661 gaaaagcttg cgcctcttga atggctgcgc gtgtttcttc tactgtttca caattttcag
    15721 accacatttc gattaggaaa ggtccattat aattggtttc ctttaaaata tcgaaagctt
    15781 cttcccattt gacacaacct tgcccaaaag gtacatctcg gaactggccc tttgaacttt
    15841 ctgtcactgc ataagtatcc ttgagatgga gagttgcgat ggcatgatga ccaagataaa
    15901 actcactata gatatcatta tgccatgcag acacattacc aatatctgga tatacaaaga
    15961 ggaagggaga gtcaatctct ttttctatag ccaaatattt ttcgatgcta ttgatgaaag
    16021 gatcatccat aatttcaata gcaagtacca cctgagcttc ttcagcccag tcacaggctt
    16081 ttctcaaatt tttgataaaa cgttggcgtg tctggggtga cttttcctca tagtaaacat
    16141 cgtaaccagc taattgaatc gtacgaactc ccaagtcttg agctaattcg atacattttt
    16201 tcatgagttc tagagatttt tcctctagaa ctggatcttt tgaacccaat gggtagcgac
    16261 gatggcctga aaaacagata gaaggaatac gaacaccagt ttcatagatt gctttgacaa
    16321 cttccaagcg ttcttcctta ctccagtcaa gtcttgctaa acgctcgtca cgttcgtcaa
    16381 tagacatctc gacaaaatca aagcctaact ccttggcaaa atttaaacgt tctagccaag
    16441 taaagtgtgt tggggttgcc ttttcataaa ttccaattgg acgtaccatg atttaccccc
    16501 aaattcgtct gatttcatcc ttgaaggcac gcgctgctcc tgctggatcc gcagcctctg
    16561 taattccacg acctgcgata aaggtaaaga catcaacacc ttcaaagagt ttgagagtat
    16621 ctacatctag accacctgtt acagatacac ggaagcccat gtcaatgagt tttttaacct
    16681 tattaaggtc tttttcaccc caagtttcac cagcaagaag agcatcacga gattggtgat
    16741 aaatagcttg tgagatacct gcatctagcc aaagctgagc ttgttcaaaa gtccaatcgc
    16801 cataaagctc gatctggatt tcgcctcgtt ctcctcgttc agtcttgata gcctttagag
    16861 ctgcttccat agtagggatg gttgcacaac agatacaagt catccagtct gctccacgaa
    16921 ccgcattatt tttagcaact gttccaccag catcagcaca ttttgtgtct gccacaataa
    16981 tcttatctgg gaaaaggcta cgcaagactt cagccagttc acttccaact tgaagcaagc
    17041 aaacagttcc agcttcgata atatctactt cctgaccaac agaaacagct gctttaatcg
    17101 ctccttgcaa gtctgaatgg tctaatgcaa cttgtaaatt aggtattctt tttgtcattt
    17161 ctttattcct ctttctaact ttccaaatcc aatccttcga gataagggct atccttagat
    17221 tcttcaatca tagccaagac atcttcttta gtctggcaag cctgtaaacg tgcaatagaa
    17281 tcgtctaatt caaacagggc aataatttgt ggaatggcta cacttgtgtg aatttttgaa
    17341 cttgttgctg ctagtgccaa caaaacagat acctctttcc catctgaaaa tacaacagga
    17401 ttttgtaagg taatcaatga aaaggcatca ctttgcacac cagcttcagg tctagcgtgg
    17461 ggcatagcta tacctggcat caagatatag taaggcccat actcttcagt cgattcaatg
    17521 atagcatcgt aatactctgg caaaattgcc ccactttcaa tcaagggatc tactgctacc
    17581 ttgactgctt ctttccaatc gttagcctct aaacctagtc ggatcgagtc gttgtcaatt
    17641 aaagcttgtt ttaaattcat atctgcctcc tttatttaaa gagggagaag gacagaaacg
    17701 ataactctca gtttctgtcc agccccctcc aaccttttac tgtagtgctt gactgagttt
    17761 ttcggtgatt tctttatcat ccatcaagtt atcaagccca attaacttcc cattagttcg
    17821 cccttccaat tcttgaatca aatgaagaga agcgattacg atgtcatatc ctactgctaa
    17881 acctttagct tcaccgacac tgcatgaatt gactgtaaaa tctgtttgat taagcttacg
    17941 gagagcattt tcaaccttca tcttgataac cattgatgaa cccattccat ttccgcacgc
    18001 tgctaatact ttaaccattt tatttctcct tttctagata ctaagcttct tcttgaactt
    18061 caccgttgta atatttctct ttatcttttg ctttggcaaa ttgaagttga ggaataacaa
    18121 gcaagaagag acacacaagt acataaccaa caataccaag gtatttgaag atatatccaa
    18181 atccaagcca tgggaattca aagtcgatat ttccatggta gccaccataa gatgccaaat
    18241 cgagaagggc cacacaaaga gctcctagag caacttgaag gacacctgat ataaaggaaa
    18301 ggataacagc cgctttccat ccgccgcgtt tatcagcgta gaccgcaatg gctgcattgt
    18361 caaagaacac tggtacaaat cctgtaataa taagaatcgg atttttaaag acgatgagca
    18421 agacaattgt aatcaattga ccaatcaaac caaaggtaaa tcctgacaag acagcatttg
    18481 gagaaccaaa tccataagaa gctgcaacgt caaccgctgg gaatgaacct ggcaacaatt
    18541 tgtttgaaat accttggaag gcgtttgtca actcagatac gaacattcgg acaccttgca
    18601 tcaaaacgaa caagtaaact gagaaggtaa aggctgtttg gataatgtac ataaagaaat
    18661 cttgtttagc aggattgaat agagttcctg aagtgatgac ttctttatta gacataatgt
    18721 ctggacccaa gattaaaaga atggccccga agaatacgag catcaaggta gcagatgcaa
    18781 caactgtatc gtggaagatt gagaggaact taggtaattt aagattgtct aaactttctt
    18841 ctttcttacc aaagcgtcct gctactttat ctacaaacca gattgcaaat tgctgttggt
    18901 gaccaatcgc aaatccgcca ccaccagtca agcgttgagt tgcctcaaca gtcatatttg
    18961 aactaactgc ccagtaaagt ccacagatga taccaatcgc tgctgtaccg taagcattgc
    19021 gcaattgtgg tactaagaat agaaccataa gagatactgt tgcagcttgt tgtaccatga
    19081 tgtgaccagt aataaagagg gttcttacct tcgtaatctt tcgaagagct acgagcaaga
    19141 tatttattcc aaaaccaatc aatagagctg tagttgcagt tccaacaaaa tctggaaact
    19201 ctgctgcaat tttgttgttt gctgcagcaa gtccaaagta agggtcgata accgctgcac
    19261 caatttggaa tttgtagtta agagctgcta agattggacg aaaggttgta accaaaccac
    19321 cagcacccac gttaagcaac atatacccta ctgttgcttt aacaaaccct gaaaaaacgt
    19381 catgggcagg ttttttcaaa agtgcatatc ctatcaacac caataaacct acgaaaaatg
    19441 cgggattctg caaaatattg ctagaaaacc aatttagaac acttgaaacg acttccataa
    19501 ttgttctcct tttgaattgt ttttgtaagt ttattatata atgcgaaagc gcaaacaaaa
    19561 agaccaagaa ttacacagcg gactgttcac tcttggactg tatgatttat gatgttttac
    19621 aaattatctt attttctcgt agctagataa tagggaagaa ttttagaata agacttcaat
    19681 aagccttcta cgatttcttc ttcagacgaa ttttctgtca taggaacatc taccttcact
    19741 aaaacttttc gaacttcttg acttctcacc ttctcgcgta aagtacgacg cttttcttca
    19801 ttcgcctccc accgttgact ttgaccatta gagtaggtta gataataaat ccctttaacg
    19861 gttggaatgt ctaaaacttt ggcctgcttg cccagtgttt gctcatcctt cttacgttcg
    19921 atgaaactga cttccaaaga aattccaaag tcagtagatg tcccatacaa acgtaaggcc
    19981 atcataggtt ctgtcacttg tccgtctctc tgtagataaa cccaaaaatg tggtctcaaa
    20041 cgctgggcct gattcatcca ctgactagtc tgttggagtt gccattctgg atggcttgct
    20101 tgaaaggctt tggccagttc tgtaaaagcc tttcgggcct cttgtccttt gtggcggaat
    20161 gccagcatct tctctcgctc tgctcccgct ttatcaggat tacggtactg caaaccagca
    20221 aagtctaaat agtctcttat cttattcaac atcagtttaa cctcctctag ctagcaaaaa
    20281 atcaggtcaa ccctgatttt acttattctg tatctacaac gacatagcga tttggctcat
    20341 caccttcaga gtaactggtc acgccatcca tacgtgaaat aatacggtgg ataatcttgc
    20401 gttcactatt cgacattgga tctgtttgat gactacgtcc ttcttctaaa acacgaatcg
    20461 ccaatttttg cgcataggtc tgcaagactt ctgcacggtg ttcgacataa tcattgacat
    20521 tgattgtaac gtagaaggtt ttggaatagc ggttgtaaag ataattttga gccaacagtt
    20581 gcaaggcctt caagacttta ccatggtagc cgataatacg acctggttcg ttggtgtcaa
    20641 tttgtagatt gatgctacga cggttataat catttgaaag tgtagcttca acatccatgt
    20701 catccacaat cgcttgaaca taggcagtca catccgtagc cacctgggca atatcataac
    20761 tttgctcgac cttcaagccc atctctttca agtcttgatt ttcagtttga tcttgctcag
    20821 tttcaaggtc atcagcgcct gcttcttccc tcatcgcttc ctcgatttga agttcattta
    20881 aaatctcaat gtgaccagtt tcttctaaga tagtgctggc atgtctttca tgttttaaga
    20941 tttcagcctt gacttcatca gaaatacctt gaccttcttc ctctattttt ttaatagcat
    21001 caaccacatg accaaggtca acggtttctt cactaaccgt cttcacaggc tcgttcaaat
    21061 cattgatttt tttcggaacg ccttttacta cctgttgatt tgctttgaca acagtcgttt
    21121 cactaatcgc ttcaatatcc acttgggctg gttttttacc aaatagacca agaaagcctt
    21181 ttttctccct agaaatgact ttgatatgag ccttcattct tggaatatct aattctttca
    21241 atcctttctg gattgcttct tcaacagttg aacctgtaaa tactaccatt accagattcc
    21301 tccttattta tttcgttttc tgagcctttt tcttggcttt tctttttcta ttttccaaat
    21361 ctttttgtgc ctgtactacg gcctcgcgct ctgcgataat cttgaatgga ttattcaaga
    21421 aataggtttg caagacttga taagcattag acactgtcca gtatagggcg actccacctg
    21481 gcgcataaac tgcaaagata aaaatcaaga ctggaatccc atacatcatc gcagtcgtag
    21541 ctccatttcg ctcagacaaa gctttgttgg acaaccaagt acttaaaaag gtgaatactg
    21601 ctgctaaaat cggaagaaca agggttgtat ccacactacc aaggttaatc cataagaact
    21661 gacctgtctt taaaaagtca actcttgata gggcttggaa cagggccaaa ataaccggca
    21721 tctgaatcaa aatcggccaa agagagtctg actgtctgac acccatttct ttaaatactt
    21781 tacgcatttc ctgctctagt ttggttctgc tttccatatc tcgacctgga tattgttctc
    21841 gaagcgcctt aatgcgtggc tgagcttcct gcattttcct agaagccacc atttgcacct
    21901 gaaagactgg caagaggact gtacgaatca agaccgtaaa gagaataatc cccactccga
    21961 tactaatatc aaacgataaa aagcgaatga tttccgcaaa gaagtaaacc aatttactcc
    22021 aaaaatcagc cgattcggct gtaatatcgc tagttacctc attagttgca caggctgtca
    22081 tgattaacag agacagtcct agcaaactag tcaactttag tttctttttc actcccattt
    22141 ccttcctggt aaatctttga taattttaat acgtggagta gatttttctc catctctgcg
    22201 tatcccaagg tttcgactcc ttttcgagca atgacaacaa agtcgacatc ttctaccaga
    22261 ctcccttttg cattctggat aatatgccga atccgtcgct taatttgatt tctagtgacg
    22321 gcattcccca gttttttgct aactgataga cctactcgaa aatggttttt ctggttttct
    22381 aattggtaga ccacaaattt gcgattagca aaacttgtcc cctccttgaa aatcgcctta
    22441 aaatctttct ctctttttac acgaaagttt ttcttcaaaa ctcaactcca tctattaaat
    22501 tactactatt ataccatatt tttcaaaaaa gccaatcata gcaaggtttt ggacaatttc
    22561 atcagaaaaa gaagctggaa aaataacttt cccaactcct tgtattgaat atttttttag
    22621 tttcacttat tttttcaagc gttcaacgtc acgggcaatg actaattctt catctgttgg
    22681 aataaccaag acacggattt tagctgcctc tgttgagatg tctcctgtaa cgccaaagac
    22741 attcttttca tcatcaacat cacaaccaaa ccacgaaatc cctgagatta catcacgacg
    22801 gaaattctct gcattttcac cgacacctgc tgtgaaaaca atggcatctg ctccatttag
    22861 cactgcaagg tactgaccga tatgtttttg gatacggtca acatacattt cataagccaa
    22921 gctagcctcg tgattccctt ctgctacagc tgcttctata tcgcgcatat cgctagaatt
    22981 agcagaaact cccaaaagac ctgattcacg gttaagaaca cgactgatat cttctggtgt
    23041 gttaaaatcc tctgtatatt gcattaaata aggaatgata gctggatcaa tatcccctgt
    23101 acgcgttccc atcataatac caccaagagg agtgaacccc atagaagtgt ctacagattt
    23161 gccggctttc acagctgtaa ttgagcctcc gttaccaata tgacaggtaa ttaacttcaa
    23221 gtcttctaat ggacgtccca agagttttgc agcttctcct gctacaaact ggtgacttgt
    23281 accatgagca ccgtatttac gaaccttgtt ttctgtgtaa tattttgttg gtagagggta
    23341 gcgataagct ttctctggca tacttgtgtg gaaggaagta tcaaaaacaa ctacactggt
    23401 aatgtctggc aacaattcct tgaaggcacg aacacctgct gcattggccg ggttgtgtag
    23461 aggagccaac aaactcaact cttcaacttt ttctaaaaca tctccctcaa caactgttga
    23521 ttctttgaaa tattctccac cagcaacaac acgatgtcca acacctgtaa tctcgtcata
    23581 agccttgata atatcgaaac gaatcaagtc atccaataaa attttaacag cttgtgtatg
    23641 attttcgata tccaaaattt gttgttcaga acggccgtca aattttacag ttgaaattga
    23701 atctttcaaa ccgatacgtt caatcaaacc tttggctaac actttttcct ctggcattaa
    23761 gtataattgc catttcaaac ttgaacttcc tgcattgatt gcaattgttt ttgtcataac
    23821 atgatacccc tttttaagcg ttttcaacta ttataacaaa atctatttta tatttcagta
    23881 ccttgagtcc atttttgaaa attttcttta aatttcatta aaacacttgc atcttgcaag
    23941 ctagcaagtg gataaacaaa aggctccact gctatttcac ttttcttctg taggataaaa
    24001 atagtcttag attgtttagc attagcaaag agattttcag gcagactaat catagcaacc
    24061 agactcgcct cttctttcag ccattctttt aacaaatcac tttgaggact ggtcaacaaa
    24121 tcactcggag ctagaaaaat agcgtatccg tctgacttga ggtacttaag cccttgttcc
    24181 atgagcaagt gatgggcgta agtatgttct tggctagaag caacttgatg gcgcgacgca
    24241 acggcatcat caggataata gccaacaggc aagtcactga tgaccacatc gctttctttg
    24301 agcatttgtg gacgaacggc atctccttgg acaaagccag cctgcaaacc aattacatct
    24361 gccatgctag ctgccagatc aatcagcaaa tcatccactt ccattcccaa ataatccacc
    24421 tttttagtaa gcgaggtcaa gaaagtagcg cccaaaattc ccatcccaga acccatttcg
    24481 aggatagtaa tttcctcctc tttaaacagc tcttccacaa taaacaccaa aagtaaagca
    24541 atagcatccg gtgtaaactg gtgattggcc tgcaagggtt ctgtttgccc agccttcatc
    24601 aagagaaact ggtaggtctt gagccattct tctttgcgta gtgctaaacg cttaagggtc
    24661 tgattgttgt ctttgacctg ttctagctca gtctcaccat ccagatagat gctgttttgc
    24721 tccaccaagg cgtcataaaa gttggtcgcc aaatcacttt ggatgacttg gacattctct
    24781 agtaaatagg tataagcttg ttcaattttt tcaaaatcca tattcctatc ttatcaaatt
    24841 tcccttcttt tttccattct tatagaaaaa tcactccctg actaggcgag tgatttttgg
    24901 gctactatta aaaagaattc tgagtgattt ccttgaaaca ggtcttcagc gctatagaga
    24961 atctgactat gcacagatga aaaaccatgc tcaattagct tgttttccag ttcagctaaa
    25021 tcaaatccat gatgattagc ttctgtcttg gtaaaatcag caatgatgag tttcccatct
    25081 tccttcaaat gttgatgaaa cagtgagaga gccgcatcca aatcaggcat atgatgaaga
    25141 acccgactaa cagcaaggca atcaaactct ttctccaagg gatttttcgg taaatcttgc
    25201 tccaaaaact ggatattctt gattgcttgc tgctccactt tcaaacgagc ttgctccaac
    25261 attttctcag aaatgtctac aagagtgact gacttagcct gcttggctag gggttagggg
    25321 caaggctaat agacccgtgc caccaccgaa atctaaaatt tctttgtctg atagaagatc
    25381 aatctgtttc tcggctgctt gacataccaa gtttgcgagg aagatatttt tagggaaatc
    25441 gaaagtttct gctttgtggt taaaatcatg tttcatatct ttaatttagc acaaagtata
    25501 gtaaactgaa ataagatata aacaaatgaa ttggagctta acatccattt ccagcaattt
    25561 tctagaaact acagtggact attctggatt caacgcatta tagttgaatt gactaggaat
    25621 tctctttctt ttcaggcttc tcttctgatt ttttcttctc cactttttcg cttgaatcgg
    25681 tcgctacctc ttccttttta tctcttttct cttctttgat tttgactgaa ggaaacagaa
    25741 actcatattg gctcttatcc gtacgaaccc tcgtcactaa gccagttttc ttgttttgat
    25801 agcttacctg acctagatta aaaacctgtt ccccactttc ttgctcaacc ttatctttgg
    25861 ttcgtttagc catagcaaaa gcaaccaatt tttctttatt caaagcatag tcttgatagt
    25921 gggcgacttg tcggttcaaa taaaattgca acaaaagact aaagatggct gctatggtga
    25981 ctgcgtagag gagaacacct gccttaactt ttttcttttt ccacacgata gatgaactcc
    26041 ctttctaagc ctttttgaaa ctggaaacga aaatgaacca gttgattgtc ctctgtaatc
    26101 tgagctgatt tgaggccata aaccataggc tgataacctc gaccacgagc attcgtttta
    26161 cgaaaatcgt ctgactttga cttaccgatg gcgatgtcct tgccatcttg cttcatgtat
    26221 aggcgattgc cttctacttt ttcgaactgc gaacggtcta attctgcctc aagttgatcc
    26281 acaaacaaga gccactcctt ttgctcgctt tgttgctggt agcgaacttc tgaaatgagg
    26341 agctgactca tagtttgaaa aaggagtaat cccccactga tgacaatgag ggcaagtagg
    26401 gattctaaca aggtaaaagc cttgacctta tggctctttg attgccaaca actgttctga
    26461 accatggtag acctccaatc ctttttcact agaaaatacc tgaatctcaa ctccgttgat
    26521 gcttacctga ttttgccccg tctgcagggc catcttagct accctcaaga cttcttcctt
    26581 ttgcaagatt tttgcttcct cttgcctatt tttttgaatt tgtcccaaaa ggagggtcgc
    26641 aatgctggca aagatagcta gagcgactac tgcttccagt aaaatcactg ccctaatttt
    26701 ttgtttcctt aatgcgttta atttttccat ttcctagata taattgatag cgaatcgctc
    26761 ctttactggt ctgaaattca accttagcca gggacgaatt gcccccagct cggtcaaatg
    26821 taatactttg gcctgatggt gcctgaattc ctttaggaac tgtcaacttt tgactgccat
    26881 tgctaagcgt ctgcccatct aaatttagat tagtcttttg ctgactggct acactgcgtt
    26941 tttgggtttc ccgatagagt tcttcaaact ccataaagaa aatctgttcc tctaccgccg
    27001 caaaagtgga ctgaacagag ccggacaagc ccaaggcaag gatactcaca agacccaaaa
    27061 ccaagagact ttccagcatg gtaaaggcct taatcattga ctttacgatt tgctcccaca
    27121 tttttatcat tgtattcttt ataagcttta gcctgttctt ccgtgatgcg tccatcttct
    27181 tttaacttgc ttaggctagc atcttcattc ttttccaagc tataaagttc tgcctggctt
    27241 tccaccacct taacaacagc tgcttttcct ttgtcattga ctgcttcttt ttgcttggtc
    27301 agattaggta caaagagcaa gaaaagcacg ctgataatca gcaagaccac caacatctcc
    27361 accaatgtaa aagctttaac cttagctttt ttcaagaatg tcatcatttt tttcatttta
    27421 aaaatttacc tccatatttt gatacatggg catgagcatt gccgcataaa gtaaaacgat
    27481 aatcagtgcc acaaagataa aaaccagtgg ctgcaccaaa ttcatggtgc ggttgactcg
    27541 ggtaaaaaag gcttcccaag ttttttcagc atagatttcc aactcactac ccagcttgga
    27601 cttaacttcc ccatactcta tgatgagact caattccttc ctaaagaaag gataggttcc
    27661 tatcgtctga gaaaattcac ggccattttt cagggtttga gccagatctt gaccgatttc
    27721 tttaaagagc tgggaacctt gttcctgcat catttgaaaa atctgcgtca gctccattcc
    27781 ctgtgaaatc atattccccc attcacgtgc ataataggct gtcaagtagg tctgcacaaa
    27841 gattccaata aagggaaggc gtgctaagat agaaaagaca ctcatcttag aacttctttt
    27901 ataaaaagtt agtgctaaaa gggcaagcac ggaaacaagc cctaccatgc ctagaaaaat
    27961 ttgtggcaga ttaccgataa ttcgggtggc aatattgcta ctatccagtt gtgggagcag
    28021 gtaattccgt agccccagca taattaagag aagaaaaccc agcaaaatca aaggataggt
    28081 cgctacttca attaactttt tcttgacctt ggccagattg tctagatatt cttctatctt
    28141 tcccaaactc aggtgaagat tgccatgaac ttcagctaga gataactgag tgacaatggt
    28201 acttgaacat cccaaacttt ccatcatttc tgagaatgat ttcccctgag acaagcctgt
    28261 acgcatctgg gtcacacact gcttgtccaa caaggaactc ctatctaaaa aggagatagt
    28321 ctccaccaga tgaaaaccgc tagaaaagag attgttaaat agggtgatga tatttttttg
    28381 cttagctgta gctaattttt tccgtctcag cctgaagact tgtgatatgt ccatctttaa
    28441 gaagctggtc aatttgctca ttccacttgg ctgcttggtg ttcttgataa tctctgtttg
    28501 caaagtcaac gattcctcct cccccgatta atctctggta gcagactcct tgcagaacaa
    28561 ctgccaattc ttcttcactc acacccaact ccagcagacg ctcataaaca cctcggatac
    28621 tcttggcgtg aatggttgaa aagactgtcg cacctgtcaa actagctctg accactgcac
    28681 gcgccgtctc gatgtcacga atttctccga taatcaagag atctggtcga tgacgcaagg
    28741 aaagtttgat tagattttca taggttagac cgattgcttc gttcaactgc aactgaagca
    28801 tgtcgtcctg cttgatttcg acaggatctt cgatggacat aacttgctgt cctttaaaga
    28861 gtgacttgga caattcatgc atcaaggtcg tcttaccact cccaaccgga ccagcaaaaa
    28921 gatagagtcc ccgttgcctg tactgcttgc ctaattcttc aatatcctga aaccaaaaat
    28981 gcaagtcctg ctcctcatcg tgcaacaaac ggataaccaa actctcatgc ccccgataat
    29041 cgcctacagt agataaacgt agagacgcca tcttctggtc ataggcataa tcacaggaac
    29101 ccagttgact acgtcttttt tctcccacat tcatacccgc cacaaactta aagtgactga
    29161 taacggctgc aaacttttca aaatcatagc taccaatttt acagcgctcg tctcctaccc
    29221 tcatatgaag ctcataggcg tctaacttgg ggacaaaata aatgtcttgc gccccttttt
    29281 tccgagccga gcgaatgatt tcttgtgcaa tttcttgaac catacttacc tcctcaccta
    29341 tactattcgc aaagcgttag aaaaataaaa aaagcaactc caaaaaagtt acttttctct
    29401 attttaattt catacggcaa gaacgattcc tttcctgact ggtttgtttt tcatagcctg
    29461 agcgtagttt ttcgtctggg ataacctgct catcctgcaa aagagccaaa gaatggtatt
    29521 gttgtaaata ctcatcacat tcatcacacc agcgttggtc ttccgggtcc caaaaaatgg
    29581 tcatcaagtc gcttctactt ttataaagag gggattcttg ttccaatcta aaccagcaag
    29641 ttttgtagta tttgagagca tcataatact ggtcaaattt tctacttgct acaatatctt
    29701 cttcccaacc ttctaagaac caccacggtt caaaatctcc gtacatttct ataacacgat
    29761 acatattcat tcattccttt gtaccgtata ttataaccaa ttccgccaga caaggaaaga
    29821 aatatgctca tttcttaatt ttttgataaa aaatccagcc atctgatgga tgactgaatt
    29881 tctatttact tatgtacaaa aatattttta ctacttaggc ttctgagata tcgttttcga
    29941 taatgacctt aatggcatgg tggtctgctg ccttactgaa gacttcgtag gctttttcaa
    30001 tttcactgag tttgaaatag tgagttacca atttttctgg ttcaatctta tgactttcaa
    30061 gcgctttcaa caattgtgga gtcgtatttg tagataccaa accagttgtt acattgatgt
    30121 tgcgaatcca aagtttatct aaatcgaatt caactggttt accatgcaca ccacagttgg
    30181 caaccgttcc gtctacaccg ataatctttt gacagaaatc aaatgttgca ggaataccaa
    30241 cagcttcgat agcgacatcc acaccacgac catctgtcaa atcataaatt tctttaatgg
    30301 ctttttcagg gtctgaagaa ttaaccttat gagtcgcacc gaatgatagg gcagtttcca
    30361 agcggttatc gtctaggtct accataatca atttagctgg tgaatagaat tgggctgtta
    30421 aaagagcagc caatccaact ggacctgaac caataatggc tacgctgcaa ccaggttcta
    30481 ctttcccttt taagacacca atttcatatc cagtaggcag aatgtctgac agcataacca
    30541 aagcttcatc tgacaagtct tctggagtat ggtaaagagt attatctgca tgagggacac
    30601 gtagatattc agcctgcata ccatcaatca agtgaccgaa aatccagccc ccttcgtctt
    30661 cacagtgagc ataaattcct tttttacagt agtagcattt accacaggca cagacgcaag
    30721 aaatcaagac cttgtcacct tttttgaagt tggaaactcc ttccccaact tcttcaacaa
    30781 tcccaatccc ttcgtggcca agaatggtac cactttggca agtaggaaca tcccctttga
    30841 taatatggag gtctgttcca caaatagtgg tttttacaat acgcacaata gcgtctgttg
    30901 gcttgcgaat aactggtttg tctacatcaa caaaagaagc aagtcctggt ttaacataag
    30961 tataggcttt cataaagcac tcctccgttt ttttatttgt aatatttata gttcaattgt
    31021 aagccttttt ctttgtttct tcaagctttt tttgtgattt ttttaacttt ttatttacca
    31081 gtaaagtacc ctgcataaaa aagcagaagt tagtctctaa cttctgcttt ctctcttatg
    31141 cttgataacg ttttacgcca tctaggtagg ttgctaccaa ttccaaatct ttatctaata
    31201 cgatgaagtc agcgtcgtag ccttcacgga tttggccaca gacgtcatcg atgtgaacgg
    31261 atttagctgg gttgaagctg gccatcatga ctgcttcatg cggattcgca attccccatt
    31321 cgaccacatt cttcaaacca tctttgagtt tgaggataga acctgccaag ttacctgtcg
    31381 atttgaggcg tgcagttcca tttgcaacga caactgggaa ttctcccaac atataatctc
    31441 cgtcttccaa tcccccagct gtcatacagt ctgtgataag agcgatgttt tctgttcctt
    31501 tttgtttgat aagaatttcg caagcctttg gatctacgtg gtgaccatca cagatcaact
    31561 ctgcataggt atgtggcaat tggtacatgg ctccaaccat acccaattca cggtgagtca
    31621 acccacgcat tccattgtag gcatgcaccc aaacactcgc tccagcatcg actgcttttt
    31681 tggcttcatc aaaagtcgcg tttgaatgtc caagagcaac cgtcacacct tcgcccgtaa
    31741 ctgtacgaac aaagtcttcc accccatcac gttctggtgc aagggcaatt ttattaagca
    31801 agccatttgc cgctttttgc caagaatgaa actcctcaac acccgggtct ctcatataag
    31861 ttggattttg tgccccctta aaagtttctg tgaaatatgg accttcataa taaatcccac
    31921 gaatcttagc acctgttgct tctttataat ggtttccaag attttcagtg actgcaagca
    31981 attgctcata agtggctgtt aaagttgtgg gtaagaaact ggtaacaccg gtactaagaa
    32041 gtccttcact catagtatgc aatgtacctt caatgttgtt gtccatcaca tctacacctg
    32101 catatccatg aatatgagta tccacaagac ctggggcaat gctataacct gtatagtcaa
    32161 tcacctcagc cccttcagga atctgctcta catgtttccc aaacttgccg tccacaagtt
    32221 ccaagtaacc acctcgacga actccgtgtg ggtagaaaaa ctgatccgct ttaatatagt
    32281 taggcataat gttaacctcc ttaaaagatt gattctacaa tttattatgt caattacatt
    32341 ataaaccttt cttttttatt tgtaaatggt atagacctat tttttggaga tattttaaaa
    32401 gagctggatt tctccaactc ttctcttttt taatacaagt tattttgatt taaccggctt
    32461 gtcttgagct gtctgcaaag ctgtggcaat cgtatctgca tacaattttg ctcctgcttc
    32521 gatagtgcta ctctcactcc cgaaatgaac ctggtctgtt ccagcccaaa tttctggatg
    32581 ctctttcgca acttgattcc aatctgctat cgtaatgtaa ggtgtcttct ctgccaattc
    32641 tctcatatag gcagcagcct tctcaacgat ggcataggtc tcttttgtct tatctccctc
    32701 ataaggagtc accaaaatca tatggtgtcc cttaggaaga tttttcacga tactgtccca
    32761 gtcatccttg taattctcag gattatttac cccagtcgca atgaccaccg tcttaggtaa
    32821 aaatttattc tggctattat ttagcatgat ttcatttgcg gtcttggttg ttacgctgac
    32881 ctgcgcgtta atctgtgctc caggaagagc tgtctgtagt gctgtatttg cccttaaagc
    32941 cactgagtca ccaattaaca tagtgccatc agcaattccc aaactgtttg catctgcccg
    33001 ttctgccatc accttggtct ggccaatatt tgttgcagct tgcttcaagc cattgacagt
    33061 caagtctgtc tcaaacgctc ccacttgtgg tgccaacaag gtcaccgtgc agacaatgat
    33121 ggtcaagatt cctgtacctg ctgcaagaat tgcgtgaata taaggcaggg gacgaagggt
    33181 ttggacaata ggtgtgttct tgcctgcaat ccaaggttcc aatacataaa atgacagact
    33241 ggcaaagcca taagaacaaa tcagagtcag taatacagca agaagatttg atgtcaactg
    33301 tgagaaaatg atatagaaag gccaatggaa aagataaacc gcatagctag tatccgctaa
    33361 aaagctgata atcttcggct cctgtatatg atgtgtcttt tcatgtaaga cacgcgccgc
    33421 cagaatcatg gcaagagctg caagactggc aagtaagaag ccgataagat aggcaaaaag
    33481 ataagtgaat ttgacaaaga aagtcaaaag aactaggaaa ccaaagcctc ctccaaaaac
    33541 taccaaagtc tttcgtaaat cccagatttt atccaactgc ttgacgaggg aagtcgtctg
    33601 acgaacgcct acaatagttg ctaacatact tcccaaaaag aatggataga catgagttaa
    33661 actggagaaa taaacagagg aataagaggt cactagaaaa ctaccaataa acatggagaa
    33721 gaaactgatc aagaaggcaa cagcagataa gagaaagacc atccccttca actgaccatt
    33781 tgatttagct tgtttggata agaaccaaac tgccaatccc caaagaatat agtagtgaac
    33841 ctcaactgcc aaactccaat tatgaacaaa caaatgagga atgaactgag attcataact
    33901 cccacctgtt aggagttcat agaagttggt cataaagcct aagacgctcg caatctggcc
    33961 accaattcca gcaacatagt cttggcgaac caagaaagta aaaggcatgg tcaccaagac
    34021 catcaaaacc acaggtggca caatccgata aaagcgtctt ctaaaaaatc ctatcaaatc
    34081 aatctcatgg tttttagaaa attcttcaat gagtagagct gtaatcagga aacctgaaaa
    34141 tgtgaaaaag acatctaccc cgaaaaatcc tccaggaaag atcgtctgaa agaagtgata
    34201 caagagtacc aaaagtaaac ctgtaatcct aaccaaggaa aaccatttaa tgcgcatacg
    34261 agtttattct tcctttcatt gtacacttta ttctatcaaa aaaagaagaa aaatcctaag
    34321 agaaaactta ggatttttag cttatatcaa ttccatttta gaaattacgt cctgacttat
    34381 tatagccata tttttccaca aaatactcac ggaattccaa gagattgtca tccatgatgg
    34441 cttgtcgcac ttgcttcatc aagttaagca agaagtaaag attgtggtag ctagtcaagc
    34501 ggataccaaa ggtttcatca gccttgagca ggtgacgaag gtaagcgcgt gtatagttat
    34561 tacatgtgta gcaatcacac tcaggatcca gtggcgtaaa gtcctcagca aactgggcat
    34621 ttttcacaac caaacgtcct tgactggtca tacaagtccc gttacgagca attcgagtcg
    34681 gtaagacaca gtcaaacata tccaccccac gaatgacccc atcgatcaag ctatctggcg
    34741 ctcccacacc catcagataa cgaggtttat tttcaggcag cagttgagtt gtaaagtcca
    34801 agaccgcatt catctcttca tgggtttctc ccactgccaa accaccgata gagtagcctg
    34861 agaaatccat gctgacaaga tcatgagctg attggcggcg aaggtcttca aatcctgcac
    34921 cttgcacaat tccaaacaaa ccttggtcat gtggacgacg gtgagccttc aaaccacgct
    34981 cagcccaacg gctggtacgc tcgatcgatt tcttaacgta gtcataaggt tgataaaact
    35041 gaggacattc atcaaaggac atcatgatgt ctgaacccag attattctga atagagatgg
    35101 ctttttctgg ggataggaac atcttagaac catttagatg atttttaaag gttactcctt
    35161 cttctgtgat attacggcta tctgctaaag aataaacctg aaaaccacca ctatctgtca
    35221 agataggctg gtcccaattc atgaacttgt ggagaccacc agcgcgtgca atgagttcat
    35281 ctccagggcg aagccagaga tgataggtgt ttgataggat aattcccgaa cccatctcct
    35341 tcaattcttc aggtgactga gttttgacag tggcttgtgt cccaactggc ataaacatag
    35401 gtgtcggaaa ggtaccgtgg ggagttatga tttctcctag acgagctcct gtgtgttttt
    35461 ctttcttaat caaacgatat ttgattggtg aatctgacat tttttacctc cgaagctggg
    35521 aaagacagtc ccagttcata cagtgtgccc aaggacacac tgtatgattt tatcaaaaaa
    35581 agtaggaact gtcacgaact atgtataaga actatggtat aataagagaa tgaactatcc
    35641 aaaaattgat ttaaaaacaa ttcgtcagga gtcaaaacat tttcaggctg ataccccccg
    35701 tctctttctc ctctatatcc ttcccagtat gctggtcatc ttatctggtt ttcttaatcc
    35761 cttatctcgg atccacggga ctgttttaga acagccattt ttcagcatac ttggccaaat
    35821 acttcaagcc tacctctttc ctctactagt ctcctttatc gggactattc ttttgaccag
    35881 ttccgtctat gcaacactga cactcatgaa agattctaaa acggagccat ctgtaaaaaa
    35941 cagcctagct ctctttgatg aggagcgctt ttctcaaacc tttttgaccc tacttctcaa
    36001 acgtttctat ctctttttat ggagtatccc taatttactt gggatttacc tcctctttta
    36061 tagtagcttt ttagccaaaa aattcgtcac cctacatcct gagtttccaa atctagatct
    36121 ctcatcagtt gaaaccgagc gtttcctcat ggtctttgga ctctactttc ttgcaagtct
    36181 catcttgatc attgtaggaa atatcctcta tattccacag tattatgcct attcacaggt
    36241 ggaatttctt ctctgtcata gtctagacct aggacaggtc ccaccaagac gaatcctaaa
    36301 aactagccgt tcctttatga agggctacaa gttccagcac tttgtcctag atttacagct
    36361 tcttccttgg tacttcctca attggattac ctttggcatt gctagttttt cactcctacc
    36421 ttatatccaa tgcactaaaa ttatgtttta ccgagcagta ttggctcgaa aacgtccaaa
    36481 agcttgaagg ttttcccctc aagctttttt ctatcaatga atttctccgc ctaccaactt
    36541 gagttcctga tctccatgtt ctatcatagc gccgattgct gcttctatcc ctcgccgaat
    36601 atccactaaa ctcatagttg gagtagtcgg tctgttcacc acctgttcca tcatataagg
    36661 aatatgcata aaacctgcct taacatatgg aaatttcttt tctaccaaat agagagcctg
    36721 atacatcaaa tggctgcaga caaaagtccc tgccgtattg gaaacagagg ccggtaatcc
    36781 ttctttttta tagcttgaac catcgcttta atcggcaaac tactaaagta ggccgaagca
    36841 ccatctgggc gaatgggacg gtcaatcggt tgattatctt cgttatcaga agtacgtgca
    36901 tcgtcttgat taatggccac tcgttcaggt gtcaaactag ttcttccacc agcttgccca
    36961 atacaaagga caaagtcagg ttgataacga ttcatctctt cttccaatac ttgagcagat
    37021 ttgtgaaaaa ctgtcggcac ctctagccaa cggacctcag caccatggat ttcagctggt
    37081 aaacctttaa tggcctcaaa agggctcaaa acctgtcact aatactttca tttctaactc
    37141 ctcaaaacca attcaatgaa acttttttct taaaaacaag tataacatat ttcccttatt
    37201 ctggattaaa aaggattagc gagattagaa tcgaccttca agtgtattta aagagtaaaa
    37261 tactaatcaa ggccaaaata gctgatccac cttgtttcaa aataattttt ttatccgctg
    37321 ttaaagagcc gtaagtcgca gcaccaatca caaataagac aaaaatagtc acaatttcta
    37381 aattctgtga gaaataaatg acatacaaga gaaagactcc tagcagagcc ttataaattc
    37441 cttgattttt gaacaatgaa cttactgacg gatgagccaa ttcttccttt tccatattaa
    37501 atacacgact agtcgcatct gattgcgtgg caatactttc caaataaaaa atgtaaaaat
    37561 gctccaaagc aacgatcgtt gttaaaataa ttgacatcta tttctcctta aatttctata
    37621 ttttcaatac ccaaaaccaa tttatttaat aaacggctga gttctgttct ctcaaactct
    37681 gttaagatac tttctatctc ttccttaacc ctgatatgtt gcagaggggg attcaccact
    37741 aactgctcct tggcatactt cgcagcctct accaacactt cccgctgatt ttcaggatta
    37801 cgatgacgct ccaccaaacc ttccgtttcc aaaattttga aatgccgtgt caaagcagcc
    37861 tgatcaattt tcaaacgctc ctgaaccgcc atttggttac aaggagaatg ctccagcaaa
    37921 aacagtaaaa tctgataccg tgtcaaacta atcccaagcc ttttttcaaa caattgcgta
    37981 ctcgcttgct cagacaagcg gagttgatac agtaaatctt gaatctctag catttcttcc
    38041 cctctctttt tattgattta tcaatatttg actaattaat tgtgatataa agtaaaatag
    38101 attgcaagaa tgttgcttaa ctcattacaa gatgataact ttccattttc cattcaaatt
    38161 gatactcaat gaaaatcaaa aagcaaacta ggaagctagt cgcaggttgc tcaaagcaca
    38221 gctttgaggt ctcagataaa actgacgtgg tttgaagaga ttttcgaaga gtatgacaaa
    38281 gaaaaaacga acgagaatcg ctttccatca cgaaagctag atctcattcg tcaaaatgat
    38341 gttatcaagt cgggtttatc cattcattga aacgtgaaca tgatcatagt gattttctgt
    38401 cacactaccg cggtctggca ttgggttcca agtgttagct ggcccatatt tgctatcgaa
    38461 tggagcatag aaacgttgtt tccagatgat gtaactaatg ccacggctgg ccatattttg
    38521 aatagcatat tccgcaatct tatcccctaa ttctgaacgt tctggtacca taaagtcgat
    38581 agccaaacct tttccgtgat ctccactgtc tcctggacga taaccactaa aggatgtaat
    38641 gccaaacaag ttagcaattt cttctttaaa ggcagctgtt tgtggttgaa gacctgcatt
    38701 ttcagatttt gctactgcaa gtccagcata atcgggcgca gctggagcct cgtaagttgt
    38761 tgaaattact ttcgtttctt ctgattgata agtagaaact gctgctgtag ctccatttga
    38821 tgatgctact tcttttgctt ctgaacttgt tgtagttgct tccactgcta atgcagcttg
    38881 agggcttgct tgtgtttcct gcttctcagc tggagtcgtt tcctgaggag ttgcttcttc
    38941 aactgggcga gttgtttcgg ccgtttgctc ctctgggaca gaagtgcccg tagatggtgc
    39001 cacttcttca gaagcaatca ctgtctttgt aacttctgaa cttgatgcta cttcttttgg
    39061 agcttctgca attggttgag aaaggtctgc aacctgaaca gtttgatcat caacggtcac
    39121 ttgattagtg gtcaaatctg ctgtcgcagt tgtcacttct tcactagagt ctgcttgagg
    39181 tgtttggatt tcaacttctg ttacttcttc tgcttcattg acagtcgttg tcaaaacagt
    39241 ttctgggaaa atcaagtcca tattagtgat tttgttcaga ttcgcaagca ctgtgacatc
    39301 tacacccaag gcttctgcaa tggtgctcaa agtatcacca tactgtacgg tataacttgt
    39361 tttgttgtcc gttttagtca aatcgttttg gatttgctca acactacgtg cagtccaaag
    39421 aacttcttct gcttgagttg ccaatactgg ggcaaatgac aaggctactg ttgacgctaa
    39481 taacattctt ttcttcattc tttcaaatcc tttcaaatga gtacctgtct atgataacac
    39541 aaaaaatgta gaaaaaaagc cctctcgggc ctatttaaca gaactgtcta ttccttgtaa
    39601 caaactaggt tacttgaaat agtttgttag gtctctgtca caaaactgac acaatctttt
    39661 tatcgttcag cctcaaaaat acgggaaata tctgctaacg cttgaatcct gtgattccct
    39721 tcataagtag actctaaaaa gttgatactt tgaatcccac tattctgggc aaattccaca
    39781 tccagagtcc gatcccctat ataataagta ttatcagaat tcaactgata cttatctagc
    39841 agataggtag ccgcttctgg acttggcttc cgcacaaagc cactctgact ggttaaaatc
    39901 tctgtaaaat aggattccac ccccaagtcc ttgagaatgg taaaagcgtt gttcccctta
    39961 tgagtatata taaactgctg aattcctgat tcgtctgccc aagctagcac ctcacgcgca
    40021 cctggcatca aaactacctg agcattcttc tcagccagac tctgggcacg cacctgattt
    40081 agcacctcaa catccagatt tctatcttct gccacccgca caagcaaatc ttgcaccgaa
    40141 tacttgaaga taaactctct caccttctcc ttatcataag gaatagaaaa ctgagcaaaa
    40201 gtctcctcaa tccctgataa aatcgcttcg taagagtcca ataaagtccc gtctaaatcc
    40261 caaataaaag ctgttttttg catttcctat cctttcaaga tcatatagcg ctggtaacga
    40321 tagcgtagaa ataaccagcg aaaaccatta tccaagagag accctgccca aataccaggt
    40381 aagccccaac caagcacaat ccccatcaga tatcctgttc caatgcggat acaccacatg
    40441 cctatacttg tcgcataaaa agggaggcgt gcatttccta atccctgcca gactgccgta
    40501 tagatgactg ttcctgtcgt cataggggtt ccaagtagtg aaaacagtgt cactagaaca
    40561 ctagcctcca ccgctagaga atcagtcgta tagagatgag ttaatggtac acccaagaca
    40621 tatatactaa aggatagggg caacatgagg aacagagaaa gccaaaaggt ttgtttactc
    40681 aaactagcaa ctcttttcca atcatcctct ccaactgctc gggccaacag catgaccgtt
    40741 gccgtagcga cgccaaaggc aggcatatag ttaaactggg tcaagacttc tccgattgca
    40801 ttcccagcaa ctgcctccgt cccaaaagaa acgaccaagg caatgatcac tacatctcca
    40861 gccctcatca taagtcgctc tccagctgct ggtaaagcca aggtcaacag ttccttatct
    40921 aaaccaaaag ttggcttccc ataaggcagt tttaattgtg accacaaaat cacaagacca
    40981 accaaacgag acagaattgt cccccaagca acaccagcta tccccatatc cagaacaaaa
    41041 atagctagac ttgaaaaaag aatattcaag gcattggata aaaaactaac atagagaggc
    41101 agacgtggat tatgcgttgc acgaatcaag gctcccagac tagtcattaa acctaagaga
    41161 acaatcgatc cgcctaccaa agatagatac agtccaccac tctcagctac atccctctcc
    41221 gtccccaaaa gtcctatcat ctctttccca gcgaagatgg acaaaaatcc taaaaggaaa
    41281 cttaatagta aggtaatctt caacgcctca gtcacatgat aggccaactt cgactggtct
    41341 ttctgcccta tgctttttga aataacactg gaaatagcag ctcccagagc gatgaaaatc
    41401 gcctgataaa tggtgataat attaccagct accgaaaccc ctgaaatagc tatcaatcct
    41461 aaatgagcaa ccaaataact gtccaccatt cccatgagca tctgcaaaaa gttttcaccc
    41521 atagctggca atgcaatatt aagaatgtct ttatttttct taaacaatct ctcctcctga
    41581 tgaaaagaaa ctcagttggt ttcccaaccg agtttactcc ctctatctta aagtcctaaa
    41641 taagcctcaa ccgctacttg catgtcagca gctgccactg ttgtcttgtg acgaacagga
    41701 gctgtctcaa gcccatcaac tgctggtggc actgcaacgc ctgagatttc atgtaattga
    41761 gccaaagctt caaagtctgt taaacctgct tttccagtta cagcttctac tgcaactact
    41821 gggaacttgt agggactagc tgttgaagca atcactgtct tagtcgcatc atcagtaacc
    41881 gcttggtatt ttctataaac tgctgaggca accgccgtat gtggatcctc aatataagaa
    41941 tctaactcat aaacacgctt gatttctgcc gctgtttctt cctcagtcgc atattcagct
    42001 gcaaagagct ccagaatctc tacatcaaaa tcagtcagtt catattgtcc ttgtgtattc
    42061 aaggtattca tgagttcagc cgtcttaacc gcatcattcc ccaaaagatg gaaaatcaaa
    42121 cgctccaagt ttgaagatac caagatatcc atagatgggc tggttgttac cttaaactca
    42181 cgtttcttgt cgtaaacacg tgtcttgaag aagtctgtca aaacattgtt atcatttgaa
    42241 gcacagatca atttaccaac tgggagaccg atttgtttgg cataaaaggc agccaagata
    42301 tttccaaagt ttcctgttgg tactgtgaag ttaatcttat caccagccac gatctcacca
    42361 gtcttgacca actgagcata ggcataaaca taataaacaa tctgtggcac caaacgaccg
    42421 atattcatag agttagcaga tgaaaattgc aacttgttgg ccgctaatct ttcacgaaga
    42481 gccacgtcgt taaacatgtg cttcacgttg gtttgcgcat cgtcaaagtt accatctata
    42541 gcgataacat gagtattgtc accattctga gtggtcattt gcaactcttg taccttgctg
    42601 acaccaccct ttggataaaa gacgataatc tcagtaccag gcacatccgc aaaccccgcc
    42661 atagcagctt tccccgtgtc accagatgtc gctgtcaaga taacaatctt gttctccaaa
    42721 ccatgtttct tagcagcagt cgtcataaag tatggcaaaa tagacaaggc catatcctta
    42781 aaggcaatcg ttgaaccatg gaaaagttcc aaattgtatt gcccatctaa tttcactaat
    42841 ggtgcaatag ctggagtatc aaatttgcta tcgtaggcat tgttgataca gtagtccaac
    42901 tcctcagctg taaagtcatc taaaaatgct gacaaaacta gcttagcaac ttcctgataa
    42961 gaagcatctt tcaatttgtc aaagtccaaa tctacctttg gataagtaac cggtgtaaac
    43021 aaaccgccgt ccgtcgccaa accttgcaaa attgcttggc tggcagttac tgtattgttg
    43081 gcatcacgcg ttgattgata aactaatgtc attactctct atcctttatc tatagtctcg
    43141 tccattatat catgattttt cagaaaattc tccctttata agagaaatta taggctcaat
    43201 tcttctctca aaggctgtaa ataggtcatt tcttccttat ttctcaccac tagtccctcc
    43261 tcagctagta ggagtaagtc tttggaaaat tcaataatcg tagtttcttc ctcatctgta
    43321 agatttttct tagaaaattg tctccttaaa aacttgtaat cataaccaaa tactttaaag
    43381 aaaggtgctg tttctaagta agcttctaac ttgtctaaat taaccaataa tcccaagtga
    43441 aaagctgcag aagcaaaagt cctatcaagt ggctgtgtac acacactacg aaactcaact
    43501 gttcctcgag tcgttaagtc ttggtactgg taactacgat gagtttcaaa atccttctct
    43561 tgggggtaaa taataacctc atccccattc agagcaaatg cttggatttc aggcgtagcc
    43621 aaatagtccc cagcctgaat aggataaaaa taataggtct gcccatcacg ttccgcagta
    43681 aaaatcgcag aatgatttag atagtcaaaa aaatcagctt catcattaag gagtctagca
    43741 ttgaccccaa cattctctgg atagatacca tgcatagatt cttcccagaa aatatccctt
    43801 gaaattttcg tatcccaatc cgcacccgaa aactcagagt ttgcaaataa ataagcctta
    43861 gccgcttcaa tttgagtaaa agcattaatc acccgtaagt agttagtttt tgaaatatcc
    43921 agctgaacct ggctcccaca gataaaagta ccatattcag ggaaatgatg taaatctgat
    43981 ttaataatat ttctactcaa attcaaataa tccatcaaca tctgatagcg tggataagcc
    44041 actggacaat tctcattttt atcccagttg ggatggatac cacagccaac aatagcatga
    44101 tttgattcag ctaactttct ctgaattaca ttcatataat tattgaaacg attttcgacc
    44161 tcttgaatcg tttcagcctt accaaatgca aactcaatcg ttgtatagga aacttcaaac
    44221 aaaatagcat cctgacttat cggatctact aactgaatca gattgccaaa atcatctacc
    44281 tttgctacgg tgagatccaa agtagaaact aaataatgaa atagatcctt tataacttca
    44341 acatctgtag catccccttc taaacttgca acaggatact ccaactcaat tccgacaaac
    44401 aattcaggat tttctttaat atttttcaaa taccgatgtt ttaataaatc gatagaacaa
    44461 gacatactac cctacacttt ctcaatctaa ataaaatttg aataactata attataccaa
    44521 aaataatata aaaaaggaac gaagaataac aacgttccta acactatact ataccggcgg
    44581 ccggggtcga accggcacgt ccttgcggac actggatttt gagtccagcg cgtctgccaa
    44641 ttccgccacg ccggcaaata gtaactgggg tagctggatt cgaaccaacg catgagggag
    44701 tcaaagtccc ttgccttacc gcttggctat accccaataa tataaaatag gcgagtgatg
    44761 gggatcgaac ccacgcatgc cagagccaca atctggtgtg ttaaccactt caccacaccc
    44821 gccataattc tattaacacg ggcagtagga attgaaccca cactgaaggt tttggagacc
    44881 ttagttctac ctttaaacta tgcccgtaaa atggaagggg agggattcga acccccgaac
    44941 ccgaaggagc ggatttacag tccgccgcgt ttagcctctt cgctaccctt ccaaaatata
    45001 taaatggcgc gagacggaat cgaaccgccg acacatggag cttcaatcca ttgctctacc
    45061 aactgagcta ccgagcctta ttgcgggagc aggatttgaa cctacgacct tcgggttatg
    45121 agcccgacga gctaccgtgc tgctccatcc cgcgttaata taaaaggagg atgtgggatt
    45181 cgaacccacg cacgctttta cacgcctgac ggttttcaag accgttccct tcagccggac
    45241 ttgggtaatc ctccaaaata gtttatacgg gaacaagccc gtgtcctctt agtgaacaga
    45301 taatattcca atcccctagt aatggactaa acactatggg cacgagtgga ctcgaaccac
    45361 cgacctcacg cttatcaggc gtgcgctcta accacctgag ctacgcgccc aagttaaaaa
    45421 cttggtacaa agaacaaagt tcaaagcggg tgacgagaat cgaactcgcg acaacagctt
    45481 ggaaggctgt agttttacca ctaaactaca cccgctaaa
//
LOCUS       DAVKBC010000013        41460 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVKBC010000013 DAVKBC010000000
VERSION     DAVKBC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.013"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..352
                     /locus_tag="VWX64_000815"
     CDS             <1..352
                     /locus_tag="VWX64_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU9190325.1"
                     /translation="VQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQAS
                     MSRKGNSQDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIKVKL
                     KGLSPVQYRTKSFG"
     gene            complement(479..682)
                     /locus_tag="VWX64_000816"
     CDS             complement(479..682)
                     /locus_tag="VWX64_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190326.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(675..1757)
                     /locus_tag="VWX64_000817"
     CDS             complement(675..1757)
                     /locus_tag="VWX64_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9190327.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1883..2665)
                     /locus_tag="VWX64_000818"
     CDS             complement(1883..2665)
                     /locus_tag="VWX64_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU9190328.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGTHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2665..4008)
                     /locus_tag="VWX64_000819"
     CDS             complement(2665..4008)
                     /locus_tag="VWX64_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU9190329.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4107..5423)
                     /locus_tag="VWX64_000820"
     CDS             complement(4107..5423)
                     /locus_tag="VWX64_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU9190330.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5617..6843
                     /locus_tag="VWX64_000821"
     CDS             5617..6843
                     /locus_tag="VWX64_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU9190331.1"
                     /translation="MKSNRYIIAFTGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7042..8616
                     /locus_tag="VWX64_000822"
     CDS             7042..8616
                     /locus_tag="VWX64_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9190332.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVSPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8880..9668
                     /gene="codY"
                     /locus_tag="VWX64_000823"
     CDS             8880..9668
                     /gene="codY"
                     /locus_tag="VWX64_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU9190333.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9668..10243
                     /locus_tag="VWX64_000824"
     CDS             9668..10243
                     /locus_tag="VWX64_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9190334.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10325..10410
                     /locus_tag="VWX64_000825"
     tRNA            10325..10410
                     /locus_tag="VWX64_000825"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10359..10361,aa:Leu,seq:aag)
     gene            10694..11824
                     /gene="ugpC"
                     /locus_tag="VWX64_000826"
     CDS             10694..11824
                     /gene="ugpC"
                     /locus_tag="VWX64_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU9190335.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(11971..12117)
                     /locus_tag="VWX64_000827"
     CDS             complement(11971..12117)
                     /locus_tag="VWX64_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190336.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            12325..13083
                     /locus_tag="VWX64_000828"
     CDS             12325..13083
                     /locus_tag="VWX64_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9190337.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13170..13682
                     /locus_tag="VWX64_000829"
     CDS             13170..13682
                     /locus_tag="VWX64_000829"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU9190338.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13864..14808
                     /locus_tag="VWX64_000830"
     CDS             13864..14808
                     /locus_tag="VWX64_000830"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU9190339.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWIKIEDDASAYGYL"
     gene            14817..15494
                     /locus_tag="VWX64_000831"
     CDS             14817..15494
                     /locus_tag="VWX64_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU9190340.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15591..16349
                     /locus_tag="VWX64_000832"
     CDS             15591..16349
                     /locus_tag="VWX64_000832"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU9190341.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNFKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16387..17709
                     /locus_tag="VWX64_000833"
                     /pseudo
     CDS             16387..17709
                     /locus_tag="VWX64_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-beta-N-acetylmuramidase"
     gene            18205..18723
                     /locus_tag="VWX64_000834"
     CDS             18205..18723
                     /locus_tag="VWX64_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU9190342.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            18853..19359
                     /locus_tag="VWX64_000835"
     CDS             18853..19359
                     /locus_tag="VWX64_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU9190343.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19359..19529
                     /locus_tag="VWX64_000836"
     CDS             19359..19529
                     /locus_tag="VWX64_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190344.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            19561..20793
                     /gene="clpX"
                     /locus_tag="VWX64_000837"
     CDS             19561..20793
                     /gene="clpX"
                     /locus_tag="VWX64_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU9190345.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            20802..21389
                     /locus_tag="VWX64_000838"
     CDS             20802..21389
                     /locus_tag="VWX64_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU9190346.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21400..21780
                     /locus_tag="VWX64_000839"
     CDS             21400..21780
                     /locus_tag="VWX64_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU9190347.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            21832..22722
                     /gene="rapZ"
                     /locus_tag="VWX64_000840"
     CDS             21832..22722
                     /gene="rapZ"
                     /locus_tag="VWX64_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU9190348.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLLELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22719..23696
                     /locus_tag="VWX64_000841"
     CDS             22719..23696
                     /locus_tag="VWX64_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU9190349.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGIEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23693..24604
                     /gene="whiA"
                     /locus_tag="VWX64_000842"
     CDS             23693..24604
                     /gene="whiA"
                     /locus_tag="VWX64_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU9190350.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24638..25606)
                     /locus_tag="VWX64_000843"
     CDS             complement(24638..25606)
                     /locus_tag="VWX64_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9190351.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25742..26599
                     /locus_tag="VWX64_000844"
     CDS             25742..26599
                     /locus_tag="VWX64_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU9190352.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERW
                     LGGWKHEKK"
     gene            26586..27365
                     /locus_tag="VWX64_000845"
     CDS             26586..27365
                     /locus_tag="VWX64_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU9190353.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27389..28741
                     /locus_tag="VWX64_000846"
     CDS             27389..28741
                     /locus_tag="VWX64_000846"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU9190354.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEALKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            28815..29189
                     /locus_tag="VWX64_000847"
     CDS             28815..29189
                     /locus_tag="VWX64_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU9190355.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29191..30039
                     /locus_tag="VWX64_000848"
     CDS             29191..30039
                     /locus_tag="VWX64_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9190356.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGMIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGSGSIAL
                     GYIPVI"
     gene            30316..31083
                     /locus_tag="VWX64_000849"
     CDS             30316..31083
                     /locus_tag="VWX64_000849"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU9190357.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTAPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31095..32279
                     /locus_tag="VWX64_000850"
     CDS             31095..32279
                     /locus_tag="VWX64_000850"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU9190358.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALESETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32276..34147
                     /locus_tag="VWX64_000851"
     CDS             32276..34147
                     /locus_tag="VWX64_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9190359.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDNQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34290..35474)
                     /gene="mntE"
                     /locus_tag="VWX64_000852"
     CDS             complement(34290..35474)
                     /gene="mntE"
                     /locus_tag="VWX64_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU9190360.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            35778..38474
                     /locus_tag="VWX64_000853"
     CDS             35778..38474
                     /locus_tag="VWX64_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU9190361.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38487..39278
                     /gene="yghU"
                     /locus_tag="VWX64_000854"
     CDS             38487..39278
                     /gene="yghU"
                     /locus_tag="VWX64_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU9190362.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39394..39804
                     /locus_tag="VWX64_000855"
     CDS             39394..39804
                     /locus_tag="VWX64_000855"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9190363.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            39816..41411
                     /locus_tag="VWX64_000856"
     CDS             39816..41411
                     /locus_tag="VWX64_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190364.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
BASE COUNT        12168 a         7781 c         9462 g        12049 t
ORIGIN      
        1 agtacaaaca atgttggaac aggcattcac agagaagcac tatgagaata cgattctcca
       61 tagtgaccaa ggctggcaat atcaacacga ttcttatcat cggttcctag agagtaaggg
      121 aattcaagca tccatgtcac gtaagggtaa cagccaagat aacggtatga tggagtcctt
      181 ctttgggatt ctgaaatcgg aaatgtttta cggttatgag aagtcgtttc agtcgcttaa
      241 gcaattggaa caagctattg tagactatat tgattactac aacaataaac gaattaaggt
      301 aaaactaaaa ggacttagcc ctgtgcaata cagaactaaa tccttcggat aaattaattg
      361 tctaactttt tggggtcagt acagaaaaac tttgatacta tgcgttttat tgtgggaaga
      421 ttttcctcat tttctagtga aattgaactt tttctaacat cttttgatag atgacttctt
      481 aatcaattat catttccatt gttgtttctt ggggtttcat cccttgtctt tgataaaagc
      541 ggagagcacc ctcgttatca ttccagacac ttagggttag attattgcag ccaatttctt
      601 tagcataata gcagaaaaat gacaataaaa tagcccctag atattttgaa aggaaagcat
      661 aggggctata tagtttaatc aaaataaagc aaatctttgc tggtgcttgt aaagaggtcg
      721 aagccatcct tggtaacaac accgcagtct tcaatacgaa caccgacttt accagggata
      781 tagatacctg gttcaacaga gaagcacatg ccttcttcga tgaccatgtc gtttccttcc
      841 atgatagatg ggaattcatg gacatccata ccgataccat gcccgagacg gtggttgaag
      901 tactcaccat aaccagcttt ttcgatgacc tcacgggcag cgcggtccac ttcatgagca
      961 gtcacacctg gcttgataaa gtcaagagca gcttgttggg cttcaagagt caagttgtaa
     1021 atatctttct tgaattggtc tggtttgccg acagcgactg tacgagtcat atctgacgca
     1081 tagccattga ccagaacacc caggtcaaag aggagaagag catcattttc aaccttatta
     1141 gctgctggaa tgccgtgtgg attcgcagca ttatcaccag tcaagaccat ggtatcaaag
     1201 ctcatttcgt aaccttcacg tttcatggca aagtcaattt gtgcgatgat atctgtctca
     1261 gtcttatcaa gagaaatatt gtcaaaacca acatgaacag ccttgtcagc ataaagacct
     1321 gcaaccatca ttttttgtac ttcatcagct gatttgatga ggcgcatgcg ttggatacga
     1381 ggagtgaggt tttcaaactc agcagtttca aaaactgttt tcaaaccatg gtatttggtc
     1441 aagatgagat tgtcaaactc aacagcgaca cgtttgaagt caagttgtgg aagagcatgt
     1501 ttgatttttt gccatggatt ttcagaatcg acatagccca ctactgggaa ggaaacggtg
     1561 ctacttgcac gttctacttc aagagctggg acaaagagga gaggttcctg atccgctagg
     1621 acaaagagga acatttggcg ttcatgggga tcactgtaaa aaccagtgag gtaattgatt
     1681 gtgacggggt cagatacgac agcgacgtct agtttttctg attcaagata tgttaggatt
     1741 tgttgtaatt tagacatatg ctaccttctt tctacccctc tattttggca aaaaatgaga
     1801 gaaaatgcaa gggagaaggg taaaagaaaa gacaaaaaac tccgacaaga taacggagtt
     1861 ctttgatatc attttccttt gtttaagaaa agtcagcctt gcttttgacg tcactgtact
     1921 cttcagcgat ttcttggctg agaatgtcct cataggcagg gagttggatg tcctgaccat
     1981 atttcttctt gagggcagta gtaactaggc gataagccag attggcatta cgagagagga
     2041 taggcccgtg gaagtaggaa ccaaagacat tcttataatg aaccccttca ccgacctttt
     2101 cttcgttgtt tccatttcca tagacaacct gtcccagcgg tttttggtca tcagagagga
     2161 aggtacgacc ttggtgattt tcaaatccat agtaggtttc atcgaaatct tcattgtgaa
     2221 tcttgatgtc accgataaaa cggttattgg tctggttgag cgtgtagtgt cccatgaccc
     2281 ctagcccttc gatacgtttt cctgaagctt caacataata ttgacccaat agttggaaac
     2341 caccgcagat agccagaact acaccgtcgt tttggatgta gttgtcaatg ctctcttttt
     2401 tagcaggtag gtcgtctgca atgatacttt gttcaaagtc ttgaccacca ccgaaaaagg
     2461 cgatgtcgta gtgattttca tcaaagtcat catggagaga aacgatgtca acggtcacat
     2521 gggttcccag tttttcagcc acatacttga gcatgaggat gtttccattg tccccgtagg
     2581 tattcatgag atttccgtag aggtgggcaa tgttgagctg ataggggtaa ttgccatctt
     2641 ttgaggaaag tgaagtataa accattagtt catctccttt ctaacaatct gacgactagc
     2701 cagcagttca cgaaattcca gcatggcagt ataagttgcc agaatatagg catgcttgca
     2761 gtcttgattc tcaatggtct tgagaacttg ctccagatta ctcgtttcag tgattttctc
     2821 agctggatag ccagtcactc ggaggcgacg agcgatttca gaatgacgaa caccgccagc
     2881 gttgatttca ggaatgtcca tgtcagtgat ttgctcaaag tctgcatccc agatccagct
     2941 agtgtcaatt ccatctgcat agttggcatt aaggaggaca gataggctaa atggataagg
     3001 tgctagtttg atcatttcga tagcttgggt tgcaccgact ggatttttaa tcaagacaag
     3061 ggtacattcc ttgtcaccga tatgaaaggt ttcttggcgt ccaaagacag cacggctctt
     3121 gtcaaatccc tgtttgatga gttgcgaatc ggcacctagg aaacgggcga tggccacagc
     3181 agctagggcg ttatagatat tatagagccc gccgatttgg ataccgtatt cttggccgtc
     3241 tatgacaaag cgagagcgat tgttggtcaa ctcaaccagt tttgtcaaac gatagtcgag
     3301 atcaggacgt ttacatccac aaccctcaca gatataggca cccaagtttg cataggtatt
     3361 atgctcatat ttgaggatgc cttggcagtc aggacagaga atcccttcgg tattgtagtg
     3421 agccagttgg gctggtcctt tttccaagtc aaaaccaaaa tactctatag ggtttggaat
     3481 agttggcttg tagaaaagtg gactgtctcc gttaaggaga acagtagcag ttggaacttt
     3541 ccgaatggca tccaatatca tgttataggt agtatagatt tcaccgaaac ggtccatctg
     3601 gtcacggaag atattagtaa tgacaaaaag actaggctgg atatagtcac agatacgaga
     3661 tagactggct tcgtcaattt cgaggacggc aatatttttc ccagttttag aagatttggc
     3721 tgttaggaag gttgttgcaa tccctgtaat catgttggca ccgcttgggt tggttagaac
     3781 ttgaccataa acctctttta aaatgccgac agtgagggca gttgtcaggg tttttccatt
     3841 tgttccagtg acaacgacaa tctcgtagtt cttagctagg ttttgtaaaa tatctttatc
     3901 aaattgaagg gcgactttcc ctgggagcgt acttccacgt ccaagacggc ttaaaacgaa
     3961 gtgggaagaa cgcccagcaa gaaggcccaa agtagttttt aagttcatgt ttctattata
     4021 tcacaaaaga gggaaaagac agatttggtg tttcgtagaa gtaaaaacag cccaaagagg
     4081 gctgtcagtt aagatgagat ttcaacttaa atcgcaaaca agtcattcaa gttctcagcc
     4141 aaggttgggt gagtgaagat ttgttttgtg aagtaagtgt aaggaatctt gttgtccata
     4201 gcaacagtaa tgatgttgat gatttcttga gaaccttctg agaagatgct tgcaccaaga
     4261 atttcttttg tttcagtatt aacaacagct ttgaaagctc cgcgaaggtc tccatttacg
     4321 tgaccacgag gcatggctgc aacagggatt tctttcactg cgtatggaag tttcaaatca
     4381 gctgcttggc tttcagtcaa accaacttgt gaaagtgcag gtgtgatgaa catagtattt
     4441 ggtacattga gacggtcctc aagtgtgtag ctgccatctc cagcaaggta gctgtaaaca
     4501 acacggaagt catcaagtga aatgtaagta aattgaagac caccgttgac atctccaact
     4561 gcaaagacac caggaacgtt tgtttgacag tgtttatcta ctttaatagc gccacgttca
     4621 gttagttcaa tatctgtatt ttcaagttga agtggttcta catttggttt gcgtccagtt
     4681 gcgtagagaa gggcgtcgaa acggtaagtt tcgtcttcag ttacgacaag cacttggtca
     4741 ccgtcgtttt taatttcagt agtatggata ttttgaagca attcaatacc gtcttcttcc
     4801 aggtattgtt tagcaagagc tgcgatggaa ggttctgcac gaggtaggaa tgtatccaag
     4861 gcatctagga ctgtaacctt gcttcctagt ttattgtaaa ggccagcaaa ttcaagaccg
     4921 atatttccgc caccaaggac tccaagtttt tcaggcaatt tatccaagct ttggatacct
     4981 gttgagtcaa agacgttttt gcttgtagca agtccaggga ttggcaagac gtttgaaaca
     5041 gcaccagtgt tgatgacgat agtttcagca gtcaattctt gtttttcatc accagcttgg
     5101 atttcgatga ctttatttga aaggaagtga gcttcagcat caaagatatc gacgccagta
     5161 ccagcaacag tcgtatagtt tttaccgttg aggcgaccag tgatcgtgtt tttggtagca
     5221 atgacttctt caaaagacaa gtctttctca gcagcaacca gcaaagtttt agttgggata
     5281 caaccgatgt tgatacaagt tccaccgtac atagctttgc tacgttcaac gagggcaact
     5341 tttttgccag ctgaagccaa tttacctgct agtgttttac cagctttacc aaatccgata
     5401 acgattaaat cataagttaa catttagagt tcctcctatt cgcatttcat tctagcacaa
     5461 gaaaaaaact tttgcacaat tctgctacgg aaaagacaga aaaagataaa aacgctttcc
     5521 agacaaaaaa ctagtaattt tttgacaagc ttgataaact aaaatcctat ctatttttat
     5581 ataagataga ataaatgttc gaaaatagga ggttttatga aatctaatcg ttatattatt
     5641 gcctttactg gggtcatttt acacttaatg ctgggttcga cttatgcttg gagtgtttat
     5701 cgtaacccta ttattgaaaa aacgggatgg gatcaggctt ctgttgcctt tgcctttagt
     5761 ctagcaatct tttgtttggg cttatcggct gcatttatgg ggcgtttggt agaaaaattt
     5821 ggtccgagag tcatggggag tctatctgct tttctatacg caggtggaaa tatcttaaca
     5881 ggatttgcaa tagaccgtca ggaactgtgg ttgttgtatc tcgcttatgg cattttaggt
     5941 gggcttggtt tgggagcagg ctatattacc cctgtgtcaa cgattataaa atggtttcct
     6001 gataaacgtg gtctcgcaac aggtttagcg attatggggt ttggttttgc ttctttattg
     6061 actagtccca tagcgcaaca tctcatcgca ggggtagggc ttgtagaaac tttttatatt
     6121 ttaggtgcaa gttactttat tatcatgctc ctagcttcac aattcattaa gcgtccaaat
     6181 gagcaagagc ttgcaatttt atctgcttca gggaaagaaa aaacagactc tctgacgcaa
     6241 gggatgactg caaatcaggc tctaaaaagc aatcggtttt atatactttg gattattttc
     6301 tttatcaaca tagcttgtgg tttaggctta atttcagcgg catcgccaat ggcacaggag
     6361 atggctggct tgtctacaag tcatgcagca gtaatggtgg gcgttttagg gattttcaat
     6421 ggatttggtc gcttgctctg ggcgagctta tctgactata tcggtcgccc tctaaccttt
     6481 agtatattac tgcttgttaa tcttttcttt tctctctcac tttggctctt tacagattcc
     6541 gttttatttg tagtcgctat gtctattttg atgacttgct atggagctgg tttttcattg
     6601 atcccagctt atctcagtga tatttttgga accaaggaat tggccgctct gcatggatat
     6661 attttaacag cttgggcaat ggctggttta gcgggaccta ttttattagc agagacttat
     6721 aaaatggctc attcgtacac acaaaccttg ttcgtttttc tcattttata cagtatcgcc
     6781 ttggctttgt cttattatct aggtcgttca atcaaaaaag aaagtcaaaa accgcttaca
     6841 tgattttctg tagaaatggg gctatctttt gctctggtct tgtgttatac tagataggtt
     6901 gcaaagaaaa cagtactttt cttttgtgga aaagaagcaa cacgatttta tatctagtta
     6961 tatgaaaata cgtcataaaa agaaaagtat aaactaagcc ctatagggtg gcttcgcacc
     7021 acctttagaa agaagaataa cgtgaaattt aatgaattaa acttgtctgc tgatttgcta
     7081 gcagaaattg aaaaagctgg ttttgtagaa gctagtccta tccaagaaca aactattcct
     7141 ttggcccttg aaggcaagga tgttatcggt caagctcaga ctggtacagg aaaaactgca
     7201 gcctttggct tgcctaccct tgaaaaaatc cgtacagaag aagcgactat ccaagctttg
     7261 gtcatcgctc caactcgtga actagctgtt caaagtcaag aagaactctt ccgctttggt
     7321 cgtagtaagg gagtcaaagt ccgttcagta tatggcggat caagcattga aaaacaaatt
     7381 aaggctctta aatctggtgc ccatatcgtg gtgggaactc caggtcgcct cttggacttg
     7441 attaaacgca aggccttgaa attacaagac attgaaaccc ttatccttga cgaagcggat
     7501 gaaatgctta acatgggctt ccttgaagac atcgaagcca ttatttcccg tgtacctgag
     7561 aaccgtcaaa ctttgctttt ctcagcaact atgccagatg ccatcaaacg tatcggtgtt
     7621 cagtttatga aagcccctga acatgtcaag attgcggcta aggaattgac aacagaattg
     7681 gttgaccagt actatatccg tgttaaggaa caagaaaaat ttgacaccat gactcgtctc
     7741 atggatgtgg cacaaccaga actcgctatt gtatttggtc gtaccaaacg ccgtgtggat
     7801 gaattgactc gtggtttgaa aattcgtggc ttccgtgcag aaggaattca tggcgaccta
     7861 gaccaaaaca aacgtcttcg tgtccttcgt gactttaaaa atggcaatct tgatgttttg
     7921 gttgcgacag acgttgcagc gcgtggtttg gatatttcag gtgtgaccca tgtctacaac
     7981 tacgatattc cacaagatcc tgagagttat gttcaccgta tcggtcgtac aggtcgtgct
     8041 ggtaagtcag gtcaatctat tacttttgtt tctccaaacg aaatgggtta ccttcaaatc
     8101 attgaaaact tgactaagaa acgcatgaaa ggtctcaaac ctgcaagtgt agaagaatcc
     8161 ttccaatcaa aaaaacaggt agctctcaag aaaatcgaac gtgattttgc agatgaaacc
     8221 attcgtgcca actttgagaa atttggtaag gatgctcgca aattggctgc tgagtttact
     8281 ccagaagaat tggcaatgta tatcttgagt ctgacagtcc aagatccaga tagccttcca
     8341 gaagtggaga ttgcacgtga aaaaccacta ccgtttaaac catcaggtaa tggtttcggt
     8401 ggtaaagcta agggaggtcg tggaggccgt cgtggggacg accgtcgaga gcgtgatcgc
     8461 cgtggcaatg gtcgccgtga tgagttcaaa aaaggaagtc gtggcaacga tcgttttgat
     8521 aaggaaaaac gttaccgtaa ggataataaa aaaccacgca atactttaag cgaaaagcaa
     8581 acaggctttg ttattcgtaa caagggcgat aaataagaaa aagcggttca aaatgaatcg
     8641 cttttttata taaggagacc gaatgtgaaa agacaaataa aattatcata ttatctttta
     8701 taatgttatg atacacaaaa ataggcaact tgtcaataga aaaggaacaa tttaattaaa
     8761 aatattctgg tttttaatta aattgtaagt caatgcaagt caataaggaa ttttcagata
     8821 attattgaaa aagagacgtt tttatgttat aatgatagcg attaaattcg aggtgaaaaa
     8881 tggcacattt attagaaaaa actagaaaaa ttacatcaat tttgaaacgc tcagaggagc
     8941 agttgcagga tgagctccct tacaacgcta ttacgcgtca gttagcggat attattcatt
     9001 gcaatgcctg cattatcaat agtaagggac gtctgcttgg ctattttatg cgttataaaa
     9061 caaatacaga tcgcgtagag caattcttcc aaactaagat tttcccagat gactacgttc
     9121 aaggggctaa tatgatttac gaaacagaag caaacttgcc tgttgagcat gatatgagta
     9181 ttttccctgt tgagagtaga gatgattttc cagatggctt gacgactatt gcaccgattc
     9241 atgtatcggg gattcgcctt ggttctttga ttatttggcg taatgataaa aaattcgaag
     9301 atgaggactt ggttcttgtt gagattgcca gtaccgttgt tgggattcag cttcttaact
     9361 tccaacgtga agaagatgag aaaaatattc gtcgtcgtac tgctgtcacc atggcggtca
     9421 ataccctttc ttactccgaa ctccgtgctg tttcagcaat tttaggggaa ttaaatggaa
     9481 atgaagggaa gttgactgcg tcagtgattg cagatcgtat cggaatcact cgctctgtga
     9541 ttgtcaatgc tcttcgtaaa cttgagtctg cggggattat tgaaagtcgc tcacttggaa
     9601 tgaagggaac ctatcttaag gtcttgattt cagatatttt tgaagaagtg aagaaaagag
     9661 attactaatg acaaaggctt taatttcgat tgattataca gaagattttg ttgctgatag
     9721 tgggaaacta acagcaggtg ctccagctca ggcgatttcg gatgccatca gcaaggtaac
     9781 tcgattagct tttgaacgag gagattatat cttctttact attgatgctc atgaagaaaa
     9841 cgattgtttc catccggaaa gtaagttatt tcctcctcat aatctgattg ggacgagtgg
     9901 acggaattta tatggagatt tggggatctt ttatcaagag catggttcag acagtcgtgt
     9961 cttttggatg gataaacgcc attactcagc tttttcaggg actgacctag atattcgttt
    10021 gagagagcgt agagtgtcta ccgttatctt aacaggtgtc ttgacggata tctgtgtcct
    10081 acatacagct atagatgcct ataatctagg atatgacatc gagattgtta aaccagctgt
    10141 tgcttccatc tggcctgaaa atcatcaatt tgccctaggt catttcaaaa atacactcgg
    10201 agctaagtta gtagatgaaa atctaaatga actttctgag taacctggtt ggtgaaaatg
    10261 aaaaaatttg aaaaaaagtg ttgacaagca tcccaaaagt tgatatacta gtaaagtaat
    10321 cgatgcgggg atggcggaat tggcagacgc gcaggactaa ggatcctgtg accgctttag
    10381 gtcgtgaggg ttcaagtccc tctctccgca taggaaaaga gttagctaaa gctagctctt
    10441 ttgtatttct ctaaaaaatt agaatccagt caaatgtagt ggagaatcag cgaaaatatg
    10501 ggaaaactga tccttgtttc tgcttttgtc tatagaagaa taataaagat tatcttcttc
    10561 aaattctccg atattctcta aagttttgtg caagttgcac agaacttgtt tatttttttg
    10621 gtcatcttgc catagaaata taaagcgttt tcatatataa tataattatt aaaagacaaa
    10681 aggagttcac ctcatggtag aattgaatct taaaaatatt tacaaaaaat atccaaacag
    10741 cgaacactat tcagttgaag atttcaactt gaacatcaaa gataaagaat ttatcgtttt
    10801 cgtaggacct tcaggatgtg gtaaatcaac tacactccgt atgattgctg gtcttgaaga
    10861 cattacagaa ggtactgcat ctatcgatgg cgtagttgtc aacgacgtag ctccaaaaga
    10921 ccgtgatatc gccatggtat tccaaaacta cgctctttac ccacacatga ctgtttatga
    10981 caacatggct ttcggtttga aattgcgtaa atacagcaaa gaagacatta acaaacgtgt
    11041 tcaagaagca gctgaaatac ttggattgaa agaattcttg gaacgtaaac cagctgacct
    11101 ttcaggtggt caacgtcaac gtgttgccat ggggcgtgcg attgtccgtg atgcgaaagt
    11161 attcttgatg gacgaacctt tgtcaaactt ggatgccaaa cttcgtgtat caatgcgtgc
    11221 tgaaatcgct aaaattcacc gtcgtatcgg agctacaact atctatgtaa ctcacgacca
    11281 aacagaagcg atgacacttg cagaccgtat cgttattatg tcagctacta agaaccctgc
    11341 tggtacaggt actatcggac gtgtagaaca aatcggtact cctcaagaag tttacaaaaa
    11401 tccagttaac aaattcgttg caggattcat cggaagccca gctatgaact tcatcaccgt
    11461 gaaattggtt ggtagcgaaa ttgtttctga cggtttccgt ttgaaagtgc cagaaggagc
    11521 attgaaagtt cttcgtgaaa aaggctacga aggaaaagaa ttgatctttg gtatccgtcc
    11581 agaagacgtg aatgcagaac ctgctttcct tgaaacattc ccagactgtg ttgtaaaagc
    11641 gactatctct gtatcagaac tgcttggttc agaatctcac ctttactgcc aagttggtaa
    11701 agacgagttt gttgcaaaag ttgatgctcg tgactacttg caaacaggtg caacagttga
    11761 gcttggattt gacttgaaca aagcacactt cttcgatgta gaaactgaaa aaacaatcta
    11821 ctaaaataaa taaaattcaa agcactacaa gaaaagatat ctctttatca attgtagtgg
    11881 agagatatca gttaatctag ggagagaaac aaaatgcttc tctccttttt gctagggaag
    11941 tcatattatg catctatatt gtgatgctct ttaatactct tcgaaaatct cttcaaacca
    12001 cgtcaacgtc gccttgccgt acgtatgatt actgatttcg tcagttttat ctgcaacctc
    12061 aaagatgtac tttgagcagc ttacggctag tttcctagtt tgctctttga tttccattga
    12121 gtattatttg tgggtaccat ctacaagtga agctatatgc gtaaactacg tgagcaattg
    12181 aattcgaact agagaggtaa taataaattt atgctatagt tatggtgact tgtatgcttt
    12241 tgattctagt ttatcaaata atagattaga attgtcagat aatatcattt tgtgttataa
    12301 tgaagaaaaa acagaggtgt tcaaatgtca gaagcaggtc ataagttttt agcaaaattg
    12361 gggaaaaaac gcttacgtcc aggtggaaag cgtgccacag attggttaat tgcagaagga
    12421 ggattttcaa aagaaaagag aatactagag gttgcgtgta ataggggaac tacagcaatt
    12481 gagttggcac agcgttttgg ttgcaagata actgctgttg atatggatgc tcaagcttta
    12541 gaagtggcta aaaaatctgc tggaacggca ggtgttgctc atttaatcag ttttgaaaga
    12601 gcaaatgcaa tgaaacttcc ttatcaagat gctagttttg atattgttat aaatgaagct
    12661 atgctgacta tgcaagccga tcaagctaag aaaaaatgtg taatggaata tctaagggta
    12721 ttaaaacctg gaggtcttct cttgacacat gatgtgcttc ttaaggaagc taaagagtct
    12781 atcagacagg aattatcaca agcaattcat gtaaatgtag gtcctttaac tcaagatggt
    12841 tgggaacagg tgatgataga atcaggttat tgtgatgtga aagcattgac tggtgaaatg
    12901 acattaatga aattatcggg tatgatttat gacgaaggtt tgctaggaac tttgaaaatt
    12961 tgtgtaaatg cttgtaaaaa ggagaataga aagcagtttt taactatgta taaaatgttt
    13021 gctaagaata aacagaaatt gggctttatt gcgatggcta gttataaatc gtcaaaacgt
    13081 tagataatta ttgaagttaa cttttccttt tttctttctt aaaaaatatg ctataataga
    13141 gagtaaaaaa ctttgaaaga aagaaaaaga tgaatttaaa agattacatt gcaacaattg
    13201 aaaattatcc aaaggaaggc attaccttcc gtgatattag tcctttgatg gctgatggaa
    13261 atgcttatag ctacgctgtt cgtgaaatcg ttcagtatgc tactgacaag aaagtcgaca
    13321 tgatcgtggg acctgaagct cgtggattta tcgtgggttg tccagttgcc tttgagttgg
    13381 gaattggttt tgcgcctgtt cgtaagccag gtaaattgcc acgcgaagtt atttctgctg
    13441 actatgaaaa agagtacggt gtcgatacct tgactatgca cgcggatgcc attaagccag
    13501 gtcaacgtgt tcttattgta gatgaccttt tggcgacagg tggaactgtt aaggcaacta
    13561 tcgagatgat tgaaaaactt ggtggtgtta tggcaggttg tgccttcctt gttgaattgg
    13621 atgaattgaa cggccgtgaa aaaattggtg actacgacta caaagttctt atgcattatt
    13681 aatgaaaaca gtccctaggg ctgttttctc tacactagga tataaaaata gactataact
    13741 agttagagaa aaactataat tgaaaactat atcttcttac agtataataa aaggactaag
    13801 tgtttgagat ttgtcttcaa acatatgcaa ttattcctga aagagtacag ttaggagagg
    13861 gttatgccga ttcgaattga taaaaaattg ccagctgttg agattttacg gacagagaat
    13921 atctttgtca tggatgatca acgtgctgcc caccaagata tccgtccttt gaagatttta
    13981 attttaaatc tcatgccaca gaaaatggtc acagagaccc agttgttgcg ccacttggct
    14041 aatacacccc tacaactgga tattgatttt ctctatatgg agagccaccg ttctaaaaca
    14101 actcgttcag agcacatgga gaccttctat aaaacttttc ctgaagtcaa ggatgagtat
    14161 tttgatggga tgatcatcac gggtgctcca gttgagcatt taccatttga ggaagtggac
    14221 tattgggagg aatttagaca gatgcttgag tggtctaaga ctcatgtcta ttcgaccctt
    14281 catatctgtt ggggggctca ggctgggctt tatctgcgct atggtgtaga aaaataccag
    14341 atggacagta agctatcagg tatttatcct caggacaccc taaaagaggg tcaccttcta
    14401 tttagaggct ttgatgatag ctatgtatcc cctcattcac ggcacacgga gatttctaag
    14461 gaagaggtct taaacaagac caatctcgag attttatcag aaggacctca ggttggggtt
    14521 tctattttgg ccagtcgtga tttacgagaa atttatagtt ttggtcattt ggagtatgac
    14581 cgtgatacct tggcaaaaga gtattttcga gatcgtgatg caggtttcga cccacatatt
    14641 ccagaaaatt actttaaaga tgatgatgtt aatcaggtac cttgtctttg ttggtcttca
    14701 tctgcagccc tctttttcag taattgggta aaccatgcgg tctatcagga gacgcctttt
    14761 gattggataa agatagaaga tgatgcatct gcatatgggt atttataaga ggaattatga
    14821 catatttaga cgcttttaaa tcaggtacct tggttttacc gagtgccctg ctcttgcatt
    14881 ttaaggaact ctttccttct agcgacgatt ttctggtttg gcaatttttc tatttgcaaa
    14941 atacgacagg cttagaagaa atgtcgccaa gccagattgc tgaaaggatt ggcaaggaaa
    15001 tttcggatgt caaccagtcc atttctaatc tgacggaaag gggactgctc cagtatcgta
    15061 ctatcgaatt aaatggcgaa attgaattgc tctttgatgc tagtttggcc ttggaacgtt
    15121 tggatgacct gtttggagca gttcattcaa gttcagacca gctaacacct caaaaccagc
    15181 tcaaggattt ggtggaaacc ttccagcagg agttgggacg attgttgacg ccttttgaga
    15241 ttgaggattt gaccaagaca ctaaaggaag atggaaccag tgctgacttg attaaggagg
    15301 ctcttcgtga agctgttttg aatggaaaac caaactggaa gtacattcag gcgattttga
    15361 gaaactggcg ccatgaagga atcaagagtg tggctcaaat tgaggccaag agagcagaaa
    15421 gagaagcaag caatcctcag ttgacacagg tatctgcaga tttcagaaat gccatggatc
    15481 tctggaagga ttaatccatg caagcaggct tgaaatccga gtaagatttg caagctgtgt
    15541 ataattgtga tagaataaat agaaaataaa ttgaaaaaga ggtatgtgaa atgtcacgta
    15601 aaccatttat cgctggtaac tggaaaatga acaaaaatcc agaagaagct aaagcattcg
    15661 ttgaagcagt tgcatcaaaa cttccttcat cagatcttgt tgaagcaggt atcgctgctc
    15721 cagctcttga tttgacaact gttcttgctg ttgcaaaagg ctcaaacttt aaagttgctg
    15781 ctcaaaactg ctactttgaa aatgcaggtg ctttcactgg tgaaactagc ccacaagttt
    15841 tgaaagaaat cggtactgac tacgttgtta tcggtcactc agaacgccgt gactacttcc
    15901 atgaaactga cgaagatatc aacaaaaaag caaaagcaat ctttgcgaac ggtatgcttc
    15961 caatcatctg ttgtggtgaa tcacttgaaa cttacgaagc tggtaaagct gctgaattcg
    16021 taggtgctca agtatctgct gcattggctg gattgactgc tgaacaagtt gctgcctcag
    16081 ttatcgctta tgagccaatc tgggctatcg gtactggtaa atcagcttca caagacgatg
    16141 cacaaaaaat gtgtaaagtt gttcgtgacg ttgtagctgc tgactttggt caagaagtcg
    16201 cagacaaagt tcgtgttcaa tacggtggtt ctgttaaacc tgaaaatgtt gcttcataca
    16261 tggcttgccc agacgttgac ggtgcccttg taggtggtgc gtcacttgaa gctgaaagct
    16321 tcttggcttt gcttgacttt gtaaaataat cagtaagtag caaaagctag gtggaacagc
    16381 attcagatgt ctgttacatt ttttatagga gaggaaagat tgaaaacaaa aattggatta
    16441 gcaagtatct gtttactagg cttggcaact agtcatgtcg ctgcaaatga aactgaagta
    16501 gcaaaaactt cgcaggatac aacgacagct tcaagtagtt caaagcaaaa tcagtcttct
    16561 aataaaacgc aaacgagcgc agaagtacag actaatgctg ctgcccactg ggatggggat
    16621 tattatgtaa aggatgatgg ttctaaagct caaagtgaat ggatttttga caactactat
    16681 aaggtttggt tttatattaa ttcagatggt cgttactcgc agaatgaatg gcatggaaat
    16741 tactacctga aatcaggtgg atatatggcc caaaacgagt gaatctatga cagtaattac
    16801 aagagttggt tttatctcaa gtcagatggg gcttatgctc atcaagaatg gcaattgatt
    16861 ggaaataagt ggtactactt caagaagtgg ggctatatgg ctcggaatga gtggcaaggc
    16921 aactactatt tgactggaag tggtgccata gcaactgacg aagtgattat ggatggtgct
    16981 cgctatatct ttgcggcctc tggtgagctc aaagaaaaga aagatttgaa tgtcggctgg
    17041 gttcacagag atggtaaacg ctatttcttt aataatagag aagaacaagt gggaaccgaa
    17101 catgctaaga aagtcattga tattagtgag cacaatggtc gtatcaatga ttggaaaaag
    17161 gttattgatg agaacgaggt ggatggtgtc attgttcgtc taggttatag cggtaaagaa
    17221 gacaaggaat tggcgcataa cattaaggag ttaaaccgtc tgggaattcc ttatggtgtc
    17281 tatctctata cctatgctga aaatgagacc gatgctgaga atgacgctaa acagaccatt
    17341 gaacttataa agaaatacaa tatgaacctg tcttacccta tctattatga tgttgagaac
    17401 tgggaatatg taaataagag caagagagct ccaagtgata caggcacttg ggttaaaatc
    17461 atcaacaagt acatggacac gatgaagcag gcgggttatc aaaatgtgta tgtctatagc
    17521 tatcgtagtt tattacagac gcgtttaaaa cacccagata ttttaaaaca tgtaaactgg
    17581 gtagcggcct atacgaatgc tttagaatgg gaaaaccctt attattcagg agaaaaaggt
    17641 tggcaatata cctcttctga atacatgaaa ggaatccaag ggcgcgtaga tgtcagcgtt
    17701 tggtattaag cgatgatttg aaagagggat gtgatagtag caccctcttt ttctttgttt
    17761 tatgatagtt catcctcgag taaattcaag atcttgctcg gaaatgaagc ttatatagta
    17821 gattgaatat agacaaagac cttgtgattg gtaaaacatt ttagaaattc atttaccttt
    17881 cctaatcgac ttggtttcat cttatttcaa tctattatag tattggggaa tttcttcaaa
    17941 ccacatcagc ttggtcagtt ctacctgcga cctcaaaact tgtgctttgg tcaagctggg
    18001 tttagtttcc tagtttgctg atggatttcc attgactata agcatccaac cctctttttg
    18061 tcttctaaag aattcttaaa ttatcagtct attgcaactt ttctcatata agttctttgt
    18121 cttgctattg gttttcctta gtagtatact aaggtagtaa tcattaagaa gtggttacaa
    18181 aaaataatga atgaggtaaa gaaaatggta gaattgaaaa aagaagcagt aaaagacgta
    18241 acatcattga caaaagcagc gccagtagca ttggcaaaaa caaaggaagt cttgaaccaa
    18301 gctgttgctg atttgtatgt agctcacgtt gctttgcacc aagtgcactg gtatatgcat
    18361 ggtcgtggtt tccttgtatg gcatccaaaa atggatgagt acatggaagc tcttgacggt
    18421 caattggatg aaatcagcga acgcttgatt acactcggtg gaagcccatt ctctacattg
    18481 acagagttcc ttcaaaatag tgaaatcgaa gaagaagctg gtgaataccg taatgttgaa
    18541 gaaagcttgg aacgtgttct tgttatctac cgttacttgt cagaactttt ccaaaaaggt
    18601 ttggatgtca ctgatgaaga aggtgacgat gtaacaaacg gtatctttgc aggcgctaaa
    18661 actgaaacag ataaaacaat ttggatgctt gcagccgaac ttggacaagc acctggtttg
    18721 taagaaataa ggaaacatag ataaatctgt aggaaatttc ttacagattt tttctatttt
    18781 gtaagctatt ccaaaccagt ctttttttga gttttttgat aaaatagtac tatcagtgaa
    18841 aaggatggaa gcatgactaa gaaaatcgta gctatttggg cccaggatga agagggtgtg
    18901 attggtaagg aaaatcgtct gccttggcat ttgccagcag aattgcagca ctttaaagaa
    18961 acaactctga atcatgctat cttgatgggg cgtgtgacct ttgatgggat ggggcgtcgc
    19021 ttgcttccaa aacgggaaac cttgattttg acgcgtaatc cggaagaaaa gatagatggg
    19081 gttgctactt ttcaggacgt ccagtctgtt cttgactggt atcaggctca agaaaagaat
    19141 ctctacatta tcggtgggaa gcaaattttt caggcttttg aagcttacct tgatgaagtg
    19201 attgtcactc acattcatgc tcgggtggaa ggagatacct atttccctga agagcttgac
    19261 ttgtctcttt ttgagacagt ttcaagcaaa ttttacgcca aagatgagaa gaatccttat
    19321 gattttacca tccaataccg caagagaaag gaagtttaat ggaacggagt ttatttggtc
    19381 tattcacggc ttttctgtgt ttcatctgct ttctggcagg agcacaagct tttcgtaaaa
    19441 agcgttacgg gctttctatc ctcctttggt taaatgcctt taccaatctg gtcaatagta
    19501 ttcatgcttt ttacatgacc ttattttaga tagaatgaca gtatagaatg gaaggaaatc
    19561 atgtctacaa atagaaaaaa tgatatgatg gtttattgct cattttgtgg caaaaaccaa
    19621 gaagaagtac aaaaaataat tgctggcaac aatgctttta tttgtaatga atgcgtggag
    19681 ttagctcagg aaatcattcg agaagaattg gttgaggaag tcttggcaga cttgtctgag
    19741 gtgccaaaac caattgaact cctccatatc ttgaaccact atgtaattgg tcaagatcgt
    19801 gccaagcgtg ccttggcagt ggcggtttat aaccactaca aacgcatcaa tttccacgat
    19861 acacgcgaag agtcagaaga tgtggatttg cagaagtcaa acattttgat gattggccca
    19921 actggttcag ggaaaacttt ccttgcccag accttggcta agagcttgaa tgtacctttt
    19981 gctattgcgg atgcgacagc tctgacggag gctggttatg tgggtgagga tgtggaaaat
    20041 atactcctca aactcttgca ggttgctgac tttaacatcg aacgtgcaga gcgtggcatt
    20101 atctatgtgg atgaaattga caagattgcc aagaagagtg agaatgtgtc tatcacacgt
    20161 gatgtttctg gtgaaggggt gcaacaagcc cttctcaaga ttattgaggg aactgttgct
    20221 agcgtaccgc ctcaaggtgg acgcaaacat ccacaacaag agatgattca agtggataca
    20281 aaaaatatcc tcttcatcgt gggtggtgct tttgatggta ttgaagaaat tgtcaaacaa
    20341 cgtctgggtg aaaaagtcat cggatttggt caaaacaata aggcgattga cgaaaacagc
    20401 tcatacatgc aagaaatcat cgctgaagac attcaaaaat ttggtattat ccctgagttg
    20461 attggacgct tgcctgtttt tgcggctctt gagcaattga ccgttgatga cttggttcgc
    20521 atcttgaaag agccaagaaa tgccttggtg aaacaatacc aaaccttgct ttcttatgat
    20581 gatgttgagt tggaatttga cgacgaagcc cttcaagaga ttgctaataa agcaatcgaa
    20641 cggaagacag gggcgcgtgg acttcgctcc atcatcgaag aaaccatgct agatgttatg
    20701 tttgaggtgc cgagtcagga aaatgtgaaa ttggttcgca tcactaaaga aactgtcgat
    20761 ggaacggata aaccgatcct agaaacagcc tagaggtgac tatggaactt aatacacaca
    20821 atgctgaaat cttgctcagt gcagctaata agtcccacta tccgcaggat gaactgccag
    20881 agattgccct agcagggcgt tcaaatgttg gtaaatccag ctttatcaac actatgttga
    20941 accgtaagaa tctcgctcgt acatcaggaa aacctggtaa aacccagctc ctgaactttt
    21001 ttaacattga tgacaagatg cgctttgtgg atgtgcctgg ttatggctat gctcgtgttt
    21061 ctaaaaagga acgtgaaaag tgggggtgca tgattgagga gtacttaacg actcgggaaa
    21121 atctccgtgc ggttgtcagt ctagttgacc ttcgtcatga cccgtcagca gatgatgtgc
    21181 agatgtacga atttctcaag tattatgaga ttccagtcat cattgtggcg accaaggcgg
    21241 acaagattcc tcgtggtaaa tggaacaagc atgaatcagc aatcaaaaag aaattaaact
    21301 ttgacccaag tgacgatttc atcctctttt catctgtcag caaggcaggg atggatgagg
    21361 cttgggatgc aatcttagaa aaattgtgag gaaaagaaaa tggcaaaaac aattcataca
    21421 gataaggccc caaaggctat cgggccctat gttcaaggaa aaatcgttgg caaccttttg
    21481 tttgctagcg gtcaagttcc cctatcccct gaaactgggg aaattgtagg agagaatatc
    21541 caagaacaga cagagcaagt cttgaaaaac atcggtgcta ttttggcaga agcaggaaca
    21601 gactttgacc atgttgtcaa aacaacttgt ttcttgagcg atatgaacga ctttgttcct
    21661 tttaatgagg tttaccaaac ggccttcaaa gaggaattcc cagctcgttc agctgtggag
    21721 gtagctcgtc ttcctcgtga tgtaaaagtc gaaattgaag tcatcgcaga gattggataa
    21781 gctagttgaa gtttggtgtt gccaaacttc ttttgatata aggagaaaaa gatgacaaag
    21841 aaacaacttc acttggtgat tgtgacaggg atgagtggcg cagggaaaac tgtagccatt
    21901 cagtccttcg aggatctagg ttatttcacc attgataata tgccgccagc tctcttgcct
    21961 aagtttttgc agctggttga aattaaggaa gacaatccta agttggcctt ggtagtggat
    22021 atgcgtagcc gttctttctt ttcagagatt caagctgttt tggatgagtt ggaaaatcaa
    22081 gatggtttgg atttcaaaat cctctttttg gatgcggctg ataaggaatt ggtcgctcgt
    22141 tacaaggaaa ccagacggag tcacccacta gcagcagacg gtcgtatttt agatggaatc
    22201 aagttggaac gtgaactctt ggcacctttg aaaaatatga gccaaaatgt ggtggatacg
    22261 actgaactca ctccacgtga gctgcgcaaa acccttgcag agcagttttc agaccaagaa
    22321 caagcccagt ctttccgtat cgaagtcatg tctttcggat ttaagtatgg aatcccgatt
    22381 gatgcggact tggtctttga tgtccgtttc ttgccaaatc cctattattt actagaactg
    22441 agaaaccaaa cgggtgtgga tgaacctgtt tatgattatg tcatgaacca tcctgagtca
    22501 gaagactttt atcaacattt attggccttg attgagccga ttctgccaag ttaccaaaag
    22561 gaaggtaagt ccgttttgac cattgccatg ggatgtacgg gtggacaaca ccgtagtgtg
    22621 gcatttgcta aacgcttggt gcaggactta tccaagaatt ggtctgttaa tgaagggcat
    22681 cgcgacaaag accgcagaaa ggaaacggta aaccgttcat gagaaaacca aagataacgg
    22741 tgattggtgg agggactgga attcccgtca ttctaaaaag tctgcgggaa aaagatgtgg
    22801 aaatcgcagc tatcgtgacg gtggcagatg atggtggttc ttcaggtgaa ctccgaaaaa
    22861 atatgcaaca gttgacaccg ccaggtgatc ttcgtaatgt ccttgtggcc atgtcggata
    22921 tgcctaagtt ttatgagaag gtctttcagt atcggttctc tgaggatgcc ggagcctttg
    22981 ctggccatcc attgggaaat ctcatcattg ctggcttgtc agaaatgcag ggttcaacct
    23041 ataatgccat gcagttattg agcaaatttt tccatacaac agggaaaatt tatccttcca
    23101 gtgaccatcc tttgaccctt catgcagtct ttcaggatgg gatagaagtg gctggagaga
    23161 gtcatattgt agaccatcga ggcataattg acaatgtcta tgtgaccaat gccctaaacg
    23221 atgatacgcc tctggccagc cgtcgagtag tgcagaccat ccttgaaagt gacatgattg
    23281 tcctagggcc aggttccctc tttacctcta ttttgcccaa tatcgtgatt aaggaaattg
    23341 ggcgggctct tttggaaacc aaggcagaaa ttgcctatgt ctgcaatatc atgacccaac
    23401 gtggggagac ggaacacttt acagatagcg accacgtgga agtcttgcat cgtcaccttg
    23461 gtcgcccttt tatcgacact gtcttggtga atattgaaaa agtgcctcag gaatacatga
    23521 attccaaccg ttttgatgaa tacttagtgc aagtggaaca cgattttgta ggtctttgta
    23581 agcaagtttc acgcgtgatt tcatctaact tccttcgtct ggaaaatggc ggtgccttcc
    23641 acgatggaga tttgattgtg gacgagttga tgcgcattat acaggtgaaa aaatgagttt
    23701 cacagtagca gtaaaagaag aaatcctggg ccaacaccat ctgagctggc atgaattatc
    23761 tgccattatc aaaatgtctg gtagcatcgg tctctcgact tcgggcttga ctttgtcagt
    23821 tgtgacagaa aatgccaaac tggcccgtca cctctatgag tcctttcttc atttctatga
    23881 aatcaaatct gaaattcgtc accaccaacg tagcaatctt cgcaagaatc gcgtctatac
    23941 cgtttttaca gatgaaaagg tgcaggattt gttaagtgat ttgcacttgg cagactcttt
    24001 ctttggcctg gaaacaggta ttgatgaggc gattttatcg gatgaggaag caggtcgtgc
    24061 ctatctctgt ggcgctttct tggcaaatgg gagcattcgt gaccctgagt caggcaagta
    24121 ccagttggaa atcagttctg tttatctgga ccacgcgcaa ggaattgcct cccttctcca
    24181 acagttttta ctggatgcca aggtgcttga gcgcaagaag ggggctgtga cctatctcca
    24241 gcgagcagaa gacattatgg acttcttgat agtaatcgga gccatgcagg cacgtgatga
    24301 ttttgagcgg gttaagattt tgcgagaaac ccgtaacgac ctcaatcggg ctaataatgc
    24361 cgagacagct aatatcgctc ggacagtttc tgccagcatg aagaccatta acaatatcag
    24421 taaaatcaaa gatatcatgg gcttagaaaa tttgccagta gatttgcagg aagtggcgca
    24481 actgaggatt cagcacccag actactctat ccagcagtta gcagatagtc tcagcacccc
    24541 tctgaccaaa agtggtgtca atcacagact cagaaaaatc aataagatag cggatgaatt
    24601 ataaaaccac gaatcctatg tgactcgtgg ttctttttta taaactggta gagtgttttg
    24661 gttgtacttt ttgttcaggg tcaatgtagt tgatagcgtt gttgacagca gttggagctt
    24721 ctccgaggcc tgtcgcaatc agatcaattt ttccgtcata gtagcagcag tcaccgatag
    24781 catagatacc tgcttggctg gattcttgtt tgctgttgac gataatcttg tgacggttga
    24841 ggtcgagccc ccagttttta aggttaccga cagaagattt gaaaccatag ttgacaaaga
    24901 ggtggtctag gtcaatggtt tcagtttcat cagatttgac ttttgtgatt tcaagtttat
    24961 caagtgtttt tccatttcca aggagttggc caggggcgaa tggtgtcttg atggttacag
    25021 atgattcttg caaggcttga acactgtgtt ccaaggcacg gaaattatct ctgcggtgaa
    25081 caagggtagt tggtgcgatt ttttcaaaag ccaaagccca atccacagcc gagtctcccc
    25141 caccaagaat cgtcactttc ttaccagcgt attgctgaat gttagaaacg tggtagtgga
    25201 tattttcata gccctcaacc ccttcaagtt ccagcggacg tggtttgaag gcaccgccac
    25261 ccatagcgat gataactgtt ttagtcaggt gacttccttt agaagttgtg atggcaaatt
    25321 cttcttcttg tttgtcaatc tcaagaaccg tttcattgag atgaataggg gtatcaaatc
    25381 catttagctg ttcaatcaag cggttagtca actcttctcc agtcaggttt gggaagcctg
    25441 gtacgtctag gatttccttt tcagggtaga gaatagcagg ttgtccacct agctggggaa
    25501 gagagtcgat gatttgaacc ttggcttggc gtaggtgggc ataaaaggct gcaaaaagcc
    25561 cgacaggacc accacccaca atggtaatat catagagttg agacatagtt tctcctttgt
    25621 tttttctagt cagtttattt tatcatattt ttgttcaatg taaaatggac taggataggg
    25681 aaaaaaatgc ccgaaaatgg tataatagga cgaaagtgtt ttgataggga ggatatcagg
    25741 gatgaatttt caacaattat ccaatctgca atattggacc agtttgtttg caagtccatg
    25801 gacgatagct atcaatctga ttgatatttt gattgttgct tatattttat accattttac
    25861 aaaagctatt gcaggaacca agattatgat tttggtacgt ggagttttgg tatttatttt
    25921 agctcaaatc cttgcaaata tgattggttt gactacgatt tcttggttaa tcaatcaaat
    25981 tattacttat ggggttattg cggcggttgt tatcttctct ccagagattc ggactggttt
    26041 ggaacgtttg ggaagagcga cagatttctt ttccaatgcc cctattagtg ctgaggaaca
    26101 gatgattcgt gcctttgtta agtctgttga atacatgagt cctcgtaaaa tcggggcctt
    26161 ggttgctatt cagcgtgtac gtaccttgca ggagtatatt tcgacaggaa tccccttgga
    26221 tgctaagatt tctgcagaac ttctcattaa catttttatt cccaacactc ccctacatga
    26281 cggtgcggtg attatcaaag aagaacgtat cgctgtgacg tctgcctatc tgcccttgac
    26341 aaaaaacaca ggtatttcca aggaatttgg gaccagacac cgggcggcta tcggtttatc
    26401 agaagtctca gatgccttga cttttgtcgt atcagaggaa acgggaggaa tttcgataac
    26461 ctataatgga aggtttaagc acaacctaac acttgatgaa tttgaaacag aattacgtga
    26521 aatcttactt ccaaaagagg aagtgggtct tagttttaaa gaacgatggc taggaggatg
    26581 gaaacatgaa aaaaaatagt ttatatatca tatcctcact cttttttgct tgtgtcttat
    26641 ttgtctatgc tacggcgacg aattttcaaa acagtaccag tgctaggcag gtaaaaacgg
    26701 aaacctatac taatacagta acaaatgtcc ctattgacat acgctataat agtgataagt
    26761 attttattag cggttttgct tcagaagtat cagtggtctt gactggtgca aatcgcctat
    26821 cgctagctag tgaaatgcaa gaaagtacac gtaaattcaa ggttactgct gacctaacag
    26881 atgccggtgt tggaacgatt gaagttcctt tgagcattga agatttaccc aatgggctga
    26941 ccgctgtggc gactccgcaa aaaattacag tcaagattgg taagaaggct cagaaggata
    27001 aggtaaagat tgtaccagag attgacccta gtcaaattga tagtcgggta caaattgaaa
    27061 atgtcatggt gtcagataaa gaagtgtcga ttacgagtga ccaagagaca ttggatagaa
    27121 ttgataagat tatcgctgtc ttgccaacta gcgaacgtat aacaggtaat tacagtggtt
    27181 cagtaccttt gcaggcaatc gaccgcaatg gtgttgtctt accggcagtt atcactccgt
    27241 ttgatacaat aatgaaggtg actacaaaac cagtagcacc aagttcaagc acatcaaatt
    27301 caagtacaag cagttcatcg gagacatctt cgtcaacgaa agcaactagt tcaaaaacga
    27361 attaaaaata gaaaaggatt ttataacaat gggtaaatat tttgggactg atggagtccg
    27421 tggagaagct aacctagaac taacaccaga attagccttt aaactaggac gttttggagg
    27481 ctatgttctt agtcaacatg aaacggaagc gctgaaagtc tttgtaggac gtgacacacg
    27541 tatttcaggg gaaatgctgg aatcggcctt ggtggcaggt ctcctttcag tagggattca
    27601 cgtatacaaa cttggtgtcc ttgcaacacc agcagtagct tacttggttg aaactgaagg
    27661 agcaagtgcc ggtgtcatga tttctgctag ccacaaccca gcccttgata acggaatcaa
    27721 gttctttggc ggtgatggct tcaaactaga tgatgaaaaa gaagcagaaa ttgaagcctt
    27781 gctagatgct gaggaagaca ctcttcctcg tccaagtgca gaaggcttag gaattttggt
    27841 agattatcca gaaggcttgc gtaagtatga aggatacctt gtttcaactg gaactcctct
    27901 tgatggaatg aaggttgcct tggatacagc taatggagca gcttctacca gtgcccgtca
    27961 aatctttgca gaccttggtg cccaattgac ggttatcggg gaaacaccag acggtcttaa
    28021 catcaacctt aatgttggtt caacacatcc agaagccctt caagaagtgg tcaaagaaag
    28081 tgggtcagct attggtttgg cctttgatgg agacagtgac cgcttgattg ctgttgatga
    28141 gaatggtgac atcgtcgatg gtgacaagat tatgtacatc atcggaaaat acctttctga
    28201 aaaaggacaa ttggctcaaa atacaattgt gacaactgtt atgtctaacc ttggtttcca
    28261 caaggccttg aatcgcgaag gtattaacaa ggcagttact gcagttggtg accgctacgt
    28321 tgttgaagaa atgagaaaat caggctacaa ccttggtggt gaacagtctg gtcacgttat
    28381 cttgatggat tacaatacca caggtgatgg tcaattatca gcagttcaat tgactaaaat
    28441 catgaaggaa actggtaaga gcttatcaga gttggcggca gaagtaacga tttatccaca
    28501 aaaattagtt aatatccgag tggaaaacgt catgaaggaa aaggccatgg aagtgccagc
    28561 tatcaaggcc atcatcgaga agatggaaga agaaatggcg gggaacggcc gtatccttgt
    28621 tcgtccaagt ggaacagagc ccctcttgcg tgttatggca gaagcgccta caacagaaga
    28681 agtggactac tatgttgata ccatcacaga tgtagttcgt gctgaaattg ggattgacta
    28741 aatcctagaa aactagatga aaataaaaaa ttatggtaca atagcttata atattgtagc
    28801 cgatggagaa agacatgaat cttaaacgtg aacaagaatt tgttagtcag tatcattttg
    28861 atgcgcgtaa ttttgaatgg gaaaatgaaa atggagctcc tgaaaccaag gtggatgtga
    28921 atttccaatt gctccaacat gaccaagaaa atcaagtgac ttccttgatt gtcatcttga
    28981 gctttatgat tgtatttgat aagtttgtca ttagtggaac aatctcacaa gtaaaccata
    29041 tcgatggccg tattgtcaat gaaccaagtg aattgaacca agaagaggtg gaaaccttgg
    29101 ctcgtccatg tttgaacatg ctcaatcgtt tgacttacga agtgactgaa attgcattag
    29161 acttaccagg aattaatttg gagttctaat atgaaattag ctgttttcac agattcctct
    29221 gcttatctca gtgcagagac cttgcaaaga gaagacttgt ttgtcttgga tattcctgtc
    29281 aatattgatg gtgaggaata tgtcgaaggc atcaatctgt ctgctgagga attttaccaa
    29341 aaaatggctc aggcttctga attgcctaag accagtcaac caagtattgc caagttagat
    29401 gagatcttaa cttcgctcaa agaacaaggc tatacacatg ccttggggct tttcctatct
    29461 tctggaattt caggttttta ccaaaatatc cagtatatgg tcgatgacta tgagggctta
    29521 accattgctt tcccagacac tttgattaca agtgctcccc taggcatcat ggttgaaagc
    29581 gtctttaatt ggcgtgatca gggcgatgat tttgccagca ttcaggataa gctagccatt
    29641 caaatcagcc gtacgtcagc ctttatcatg gtagatgact tggatcattt ggtaaaaggt
    29701 ggacgccttt caaatggggc tgccattttg ggcaatttgc ttagcattaa gccaatcctt
    29761 tattttaacg atcaaggtat gattgaagtt tacgaaaaag ttcgtactga aaagaaggcc
    29821 accaaacgct taattgaaat catcaaggaa acaacggctt caggtcaata ccgggtcatt
    29881 gtcattcatg ggaatgctcc tgaaaaggct gaagaattgc gtcagcattt gcttgatttt
    29941 ggcttgggtt cggatgtttc acttgctaca tttggtagtg tcattggaac gcacctagga
    30001 tcaggaagta ttgctctggg ttatattcca gtgatttagt tggcgcttct aggctagtta
    30061 agatgccttg tatcttagaa attgaacacg gactacctgc ctcttgaaaa aagatgcctg
    30121 tcttgccttt cgtggaaagt cagtgccatt ccctattttt caggggcagc taaggtcctt
    30181 tgtatcttga taattgaaca cgcctggaac cctgtgtgaa aaagatagtt cttccaagaa
    30241 gtagacactt cttgattgga attcctattt tcactttgtg ttcttacgga ctttgtatct
    30301 tagacaggag tagagatgag tattcgagta attattgccg gttttaaggg aaagatgggc
    30361 caggctgctt gtcagatggt cttgactgct ccagacttgg acttggtagc agttttggat
    30421 ccttttgagt ctgagtcaga atggcagggt attcctgttt tcaaggataa ggctgattta
    30481 gctggttttg aagcggatgt ctgggtagat tttactactc cagctgttgc ctacgaaaat
    30541 acacgttttg ctcttgaaaa tggctttgct ccagtagttg gaacgactgg tttcacgagt
    30601 gaagaaattg cagagctaaa agaattttct cgtgcccaag acttgggtgg cctgattgcc
    30661 cctaactttg ccttgggtgc tgtcttactc atgcaatttg cgacgcaggc tgccaaatat
    30721 ttcccaaatg tggagattat tgagctccat catgacaaga aaaaggatgc tccgagtgga
    30781 acagccatta aaacagctga gttaatggca gaggttcgag agtccattca gcaaggcgca
    30841 gcagatgagg aagagctgat tgctggtgct cgtggtgctg actttgatgg tatgcgcatc
    30901 cactcagttc gtttgccagg cttggtagct catcaggaag tcatctttgg caatcaggga
    30961 gaagggttga ccctccgtca tgactcctat gatcgcatct ccttcatgac aggagtcaat
    31021 ttgggaatta aagaagttgt caagcgtcat gagcttgtct atggattaga acacttatta
    31081 tgagattaac gcaaatgcct tctgaatttc agaaggcttt accagtatta gaaaaaatta
    31141 aagaagcagg ctttgaggct tattttgttg ggggctctgt tcgagatgcc cttctccata
    31201 gccctatcca cgatgtggat attgcgacgt cttcttatcc agaagagacc aagcagattt
    31261 ttccgcgaac agccgatatc ggaatcgagc atggaaccgt cttggtctta gatggggatg
    31321 aggagtatga ggtaacaacc tttcggacag aggatgtcta tgtggactat cgcagaccca
    31381 gtgcggtttc ctttgtacga tcgctagaag aagacctcaa acgccgtgat ttcacagtca
    31441 acgcctttgc cttggatgag acaggagaaa tcgttgactt gttccatggt ttagaagatt
    31501 tggaaaagca agtcttgcga gcagttggag tggctagtga gcgtttcaac gaagatgctt
    31561 tacggattat gcgtggtttc cgttttcagg ctagtcttgg ttttgcactt gagtcagaaa
    31621 catttaaagc tatgaagacc ttgacgccgc ttttggagaa aatttctgta gagcgtacct
    31681 tcgtcgagtt tgataaactc ttgctggctc cattttggag aaggggcttg gcttccatga
    31741 ttgagagtca agcttatgac tatctccctg atatggcatc tagccaggac aagctcaaca
    31801 gactgtttga tttggagact gattttactt ttgaatcctc tgaacaagcc tgggcggctt
    31861 tactatgggc tttggagatt gaaaatgcgc agtcattttt gaaatcttgg aagacctcac
    31921 gccagtttgc caagcaagtt caggatttgc tgattatttt ggctctgcgt gaaaatggag
    31981 aattgagcaa gcgagattgt tatcgctttg acatagattt gcttttacag gctgaaaatc
    32041 ttcgtcaagc tcaaggaaaa gaagtcaacc cacaagccat cacagaaaaa taccaaagct
    32101 tgactatcca tgacaagaaa gagattcaga ttaatggcgg tattttgatc aaggaatatg
    32161 gctatcagcc aggcccagac ttgggagaga ttttaacaga gattgagttt gccattgtcg
    32221 atggagaatt ggagaataat cgtgaagcca tccatgctta cctgagggag aaaaaatgag
    32281 tgattttatc gttgaaaaac taagtaaatc cgttggtgac aagaccgttt ttagggatat
    32341 ttcctttatt atccatgact tagacagaat tggtttaatc ggtgtcaatg ggactggcaa
    32401 gaccaccctt ttggacgtcc tttctggtgt ttctggattt gatggggatg tcagtccttt
    32461 ttcagctaaa aatgattacc agattggtta cttgactcag gatcctgatt ttgatgatag
    32521 aaagacagtt ttggatacgg ttctatctag tgaactcaag gaaatccagc tcattcgtga
    32581 gtatgaattg attatgctcg actatagtga ggacaatcag gcgcgtttgg aacgtgtcat
    32641 ggcagagatg gactctctcc aagcttggga aatcgagagt caggtcaaga ccgttcttag
    32701 caaattgggc attcaagact tatctactcc tgttggggaa ttgtcaggtg gtctgagaag
    32761 acgggtacag ttggcacaag tcttacttgg caaccacgac ctcttgcttt tggatgagcc
    32821 gaccaaccat ctggatattg cgattattga gtggctgacc ctctttttga aaaattctaa
    32881 gaagaccgtc ctttttatca ctcacgatcg ttatttctta gacgctttgt caacacggat
    32941 tttcgagttg gagcgagcag gcttgacaga atatcagggc aattaccagg actatgttcg
    33001 ccttaaggca gaacaggatg agcgcgatgc agctctactt cataaaaaag aacaactcta
    33061 caaacaagaa ctggcctgga tgcgcagaca accgcaggca cgtgcgacca agcaacaagc
    33121 tcgtatcaat cgtttccatg atctgaaaaa ggaagtttca ggcagtagtg ctgagacaga
    33181 cttgactatg aactttgaaa ccagtcggat tgggaagaaa gtcatcgagt ttcaggatgt
    33241 ttcctttgcc tatgaaaata agcccatttt gcaaaatttt aatctcttag ttcaggctaa
    33301 agaccgtatt ggaattgttg gggacaatgg tgttggaaaa tcaaccctac ttaacctgat
    33361 tgcaggaagt cttgagccga cagcaggaca agttgtgatt ggggaaactg ttcgcatcgc
    33421 ctatttctct caacaaattg agggtttgga tgaaagcaag cgtgtgatca attacctgca
    33481 ggaagtggca gaggaggtca agaccagtgg tggttctacg acttccatcg ctgagttgct
    33541 ggagcaattc ctcttcccac gttcgacgca tgggactttg attgagaaat tgtcaggggg
    33601 tgagaaaaaa cgtctttatc tcctcaaact gcttttggaa aaaccaaatg ttcttctttt
    33661 agacgagcca accaatgacc tagatattgc aactttgaca gtcttagaga atttcttgca
    33721 aggttttgca ggtcccgttt taacagtcag tcacgaccgc tatttcttgg ataaggtagc
    33781 gaccaagatt ctcgcttttg aggatggcaa gattcgtcct ttctttggtc attacaccga
    33841 ctatcttgat gaaaaagctt ttgaaacaga tatggccaat caagtgcaaa aggccgaaaa
    33901 ggaaaaagtg gtcaaggttc gagaagacaa gaaacgcatg acctaccaag aaaagcagga
    33961 gtgggcaagt attgaaggtg atattgaaac cttggaaaaa cgtatcgctg ctattgaaga
    34021 ggaaatgcag gctaacggct ctgactttgg taagctggct actctccaaa aagaattgga
    34081 tgagaaaaat gaagcactcc ttgaaaaata cgaacgctat gagtatctca gtgaatttga
    34141 tagttaagac tattcgaaaa tcaaagtgca aactatgtcg gcttcacatt gccgactcaa
    34201 gtacagcctg tgaccggctt cctaatttgc actttgattt ttattgagta taaaagaata
    34261 gaaaaatccc gtctcatgaa aggatttctc tattcttttt tggtttcttg atgaaagata
    34321 ttttgccagg tttcgtggcg acgccagata ctggtatgga tgataccatc taactcatag
    34381 cagatgagtt tggttttttg actgatggaa gtaatttgaa tgtccttgat agcagaattt
    34441 aactcttttt ttgtcttata agcctcttta tccatctgct ctccatcttg gcgaatatag
    34501 acaaaatcat cagtcaagag ttcttctagt tggtttcctt ggtcaatcaa ttgttcacgc
    34561 ataagcaatt ttttatagac attgtctaaa atttcatcct cagggatagg tgctggttcg
    34621 atatggacat cggtatcaaa gacgccaaaa cgctcctcca gcatagactc gacctgatcc
    34681 gcgatttcat ggctttcaaa aacagacaag tcaggattca tctctagtgt aatatccagg
    34741 tagatgttgc taccgtaggt gcgacctctt tgcgatttga ccttgctgat tttgggaatt
    34801 tccatgatag ccttttggta gtcctcgagc aggcggtcgt caaagccatc tgaaagacta
    34861 aaggaagact cgatgaagat atcataggca gtcttcaaga taaagaaagt gatgatgata
    34921 gcaaccagtt tatccacaat cggataatta aaactactag ctaggatggc aatggcggtt
    34981 ccaagtgagg taacagcgtc agaaagattg tccttagcag ctgccttcag cgccttggag
    35041 ttggatttct tactgaggcg agtattgtag agatagacca caaacataat cgctgcagaa
    35101 atgattccta gagttgcacc aagaggatca atgaccgttt cttcccgact gagaatcttt
    35161 tgaatggtat ctcttagaac atcgaaaccg acatagaaca tgatgataga agtgatcaag
    35221 cttgccaaat cttcaatctt ccaatgacca aaacggtggt cacggtctgc aggctggcgc
    35281 gccatccgaa tcccgattaa gagggccaca tttccaatga tgtccgatac gttattaaaa
    35341 ccatcggcca ccaaactgga tgaatgaagg agatgaccag ctgctaattt agctgcagac
    35401 aagatcaaat aggtcgaaat actgataatg gctccacgct cagctaactt gagatttgag
    35461 atagattgct tcattcaact tcctttctag tcacatagca ttctaccatt atactggttt
    35521 tcaaggaaaa attcaaataa ggcagttttt actctttgaa aactccccaa aatttggtat
    35581 aatggtacta ctcaagggag tagctggcag aaacctgtga tagtgtcgtc attccgaatt
    35641 ttatgctgaa aagtatgctt tccggcccta tcttaaacag cgagacttgt tatgattaac
    35701 aggtctcttt ttgtttgtcg tgaaaagata tgacagaaag agagtctgtt ttgcacacaa
    35761 tgtcaaggag gagacacatg tcaaaagaac aaaaacgcca agcgttttat actcagagcc
    35821 ctgaagaggt cttgcaggct gtggatgcga ccgagcaagg tttgtcatca agtgaggcgg
    35881 aaaagcgcct tgccgaattt gggcacaatg aactcgaaga aggcgagaaa cgatcaatct
    35941 tggtcaaatt catcgagcaa tttaaggatt tgatgattat catcctagtt gcggcagcaa
    36001 tcttgtcagt cgtgacttct ggtggggaag atatcgcaga tgccattatc atcctagctg
    36061 tggttatcat caacgctgcc tttggtgttt accaagaagg aaaagctgaa gaagctattg
    36121 aagccctcaa atccatgtct agtccagttg cccgcgttct tcgtgatgga cacatggcag
    36181 agattgactc taaagaattg gtaccaggcg atatcgttgc ccttgaagca ggtgacgtgg
    36241 taccagcgga cctacgtttg atagaagcca actctcttaa aattgaagaa gcagccttga
    36301 caggtgaatc tgtaccagtc gaaaaagact tgtcagtcga gcttgcgaca gatgctggta
    36361 ttggtgaccg tgtcaacatg gccttccaaa actcaaacgt aacctatggt cgtgggatgg
    36421 gtgttgttgt caatacaggt atgtacactg aagttggtca tattgctggt atgcttcaag
    36481 atgcggatga gactgataca ccactcaaac aaaacttgaa caacctttct aaggtcttga
    36541 cctatgctat cttggtcatt gcccttgtta cttttgtagt gggtgtcttc attcaaggga
    36601 aaaatccact tggtgagttg ttgacttctg ttgcccttgc cgttgcagcc attccagaag
    36661 gacttcctgc tatcgttacc atcgttcttt ctcttggtac tcaagttttg gccaaacgac
    36721 attccatcgt tcgtaagttg ccagcagttg aaacacttgg ttcaactgaa atcatcgctt
    36781 ctgataagac tggtacgctg actatgaaca agatgacagt cgaaaaagtc ttctacgatg
    36841 cggttctaca tgactcagct gatgatattg aactaggtct tgaaatgcca ctacttcgtt
    36901 cagttgtctt ggccaatgat acgaaaatcg atgtggaagg taacttgatt ggtgacccaa
    36961 ccgaaacagc ctttatccaa tatgccttgg acaagggcta tgatgtcaaa ggtttcttag
    37021 agaaatatcc tcgtgtagct gaattgccat ttgactctga ccgtaagctc atgtcaacag
    37081 ttcacccatt gccagatggt cgtttccttg tagcagtcaa gggtgcgcca gaccaactct
    37141 taaaacgttg tcttcttcgt gataaggctg gggatattgc tccgattgat gagaaggtta
    37201 caaatctcat tcacacaaac aattctgaaa tggctcatca agccttgcgt gtccttgcag
    37261 gtgcttataa gattatcgat agtattccag aaaatctcac ttctgaagag cttgaaaatg
    37321 atttaatttt tactggtttg attgggatga ttgaccctga acgtcctgaa gccgctgagg
    37381 ctgttcgtgt ggctaaggaa gcgggaatcc gtccaattat gattacaggt gaccaccaag
    37441 acacagcgga agccattgcc aaacgtttgg gaatcattga cgcaaacgat acagaaggtc
    37501 acgttttaac tggtgctgaa ctcaatgaac tgtcagatga agaatttgaa aaagtcgttg
    37561 gtcaatactc tgtttatgcc cgtgtgtctc cagaacacaa ggttcgtatc gtcaaggctt
    37621 ggcaaaaaca aggtaaagtc gttgccatga caggtgacgg tgtcaatgac gcgccagctc
    37681 tgaaaacagc cgatatcggt atcggtatgg gaatcactgg tacagaggtt tctaaggggg
    37741 cttctgatat gattcttgca gatgataact ttgcgactat tatcgtcgca gtggaagaag
    37801 gacgtaaggt cttctcaaac attcaaaaga ctattcagta cctactttct gctaatactg
    37861 ctgaagtatt aaccatcttc ctatcaacct tgtttggttg ggatgtctta cagccggttc
    37921 atcttttgtg gatcaacttg gtaacggata ccttcccagc tatcgctctt ggtgttgaac
    37981 ctgcagaacc tggtgtcatg aatcataaac cacgtggacg caaggcaagc ttcttctcag
    38041 gtggtgtttt gagttctatc atttatcaag gtgtactcca agcagctctt gttatgagtg
    38101 tttatggcct tgcgattgct tacccagttc atgtgggtga caatcatgct attcatgcag
    38161 atgccctaac gatggccttt gcaacccttg gtttgattca gctcttccat gcctacaatg
    38221 tcaagtctgt ctaccaatcc atcttgacag ttggcccatt caagtctaag acctttaact
    38281 ggtccatctt ggtatccttt atccttctca tggcaacaat cgttgtagaa ccgcttgaag
    38341 gaatcttcca cgtaaccaaa ctagacttgt cacaatgggg aattgttatg gctggaagct
    38401 tctcaatgat tatcatcgtc gaaatcgtta agtttattca acgcaaactc ggttttgaca
    38461 agaatgcgat ttaagggagg tttcggatgt cagcatatca attaccgacc gtatggcagg
    38521 atgaagctag taatcaagga gcttttacgg ggctaaacag accaacagca ggtgcccgtt
    38581 tcgaacaaaa cttgccaaaa ggagaacaag cttttcagct ttattcactg ggaacaccaa
    38641 atggtgtgaa ggttactatc ttattggaag aattactaga agctggtttt aaggaagcgg
    38701 cttacgactt gtataagatt gctatcatgg atggggatca attcggctca gactttgtga
    38761 agctcaatcc aaattccaag attccagcct tattggacca gtcaggtact gaaaacgtaa
    38821 gagtctttga gtctgctcat attcttcttt accttgctga gaaatttgga gcctttttac
    38881 caagtaatcc tgtggaaaag gtagaagttt tgaattggct attctggcaa gcaggtgcag
    38941 caccttttct aggtggggga tttggacatt tcttcaatta tgctcctgaa aaattggaat
    39001 atcctattaa ccgttttacg atggaagtga aacgccagtt ggatttattg gataaggaat
    39061 tggctcagaa accttatatt gcaggcaatg actatacgat tgcagatatt gctatctggt
    39121 cttggtatgg acagttagtt caaggaaatc tttaccaagg ttctgcaaaa ttcttggatg
    39181 cctcaagtta tcaaaatcta gtaaaatggg cagaaaaaat tgccaatcgt ccagctgtta
    39241 agcgtggctt ggaagtaact tatacagaaa ttaaatagca aaaaagtcat cttcggatgg
    39301 ctttttgcta cagttgaggg aaagggtttg cagttatcgg cttttgtgct ataattgcta
    39361 taatatagta aaaagccaga ggagtgtgag gaagtggaaa agaaaattgt gaaggatatc
    39421 ttatttttat ctcaagtgtc tcagccggca agtcaggagg acctttatct tgccagagat
    39481 ttgcaggata cactcttagc aaatcgtgat acctgtgttg gtctagctgc caatatgatt
    39541 ggggtgcaga agcgcgtgat tatctttaat cttggcttag ttcccgtggt catgtttaac
    39601 ccagtgcttc tgtcctttga aggatcttat gaggcagaag aaggctgttt gtccttggta
    39661 ggtgtgagat caactaagcg ttatgaaacc ataaggcttg cctatcgtga cagcaagtgg
    39721 caggaacaga ccattacctt gacaggcttc ccagctcaga tttgccagca tgagctggat
    39781 cacttggaag gacgaatcat ttaggaggaa agcaaatgaa acgaatagtc tttgaactta
    39841 tttttatcgc aacgacctgg tatatctttt taccgcccct taacctgacc agctgggaat
    39901 ttctcttctt cctctgtggg catttgttag ttgtggcaat cttatttggc tttggcaagg
    39961 ggataaacct tgtcaaaacg gttcatgtgc gccacggtaa ggcggaagct gccttaaatc
    40021 ttgagggttt caaaatcaat cggttaggga aaattctgtt agcttcgatt ggaggaattc
    40081 ttctcttggc agctttggtt tccttggtaa cttccagcat gtttcaggct aaaaattatg
    40141 ccaatgtagt cacggttacg gaaaaagact ttactgaatt tcctaagagt gacaccagta
    40201 aggttcctat cctagataga agtactgctg aaaaaattgg agaccgctac ttgggttccc
    40261 taaccgataa ggtgtcgcaa tacgtagcgg cagataccta tacccaattg acaattgatg
    40321 ggaaacctta tcgggtcaca ccactagaat atgcagaccc tatcaaatgg tttaacaatc
    40381 aagccaaggg aatcggtgag tatatcaagg tggacatggt aactggaaat gcggatttgg
    40441 tggacttgaa gacaccaatc aagtattcag actcggagta ttttaaccgt gatgtcaaac
    40501 gtcacctgcg cttgaagtac ccgaccaaaa tctttaaaac tccatctttt gaggtggacg
    40561 atgagggcaa tcctttctat gtagcaacgg tttaccaaaa gcaatttgga cttgcggttc
    40621 ctcgtcctgc ttcagtcatt atcttggatg ctacaaatgg agaaaccaag gaatacagct
    40681 tatcagatgt tccagaatgg gtggatagga tctatccagc agaggaaacc attgagcaaa
    40741 tcaactacaa cggcaagtac aaggacggtt tcttgaatgc catgatttcc aagaaaaacg
    40801 tgacccagac taccaatggc tataattact tgtctatcgg taatgacatc tatctctaca
    40861 caggtgtgac gtcggctaat gcggatgaga gtaatcttgg tttcatcctt gaaaatatgc
    40921 gaacaggaga aatcactaag tatagcttgg cttctgcgac agaagaatca gcccgtgaat
    40981 cagcagaagg tgctgttcag gagaaatcct acaaagcaac cttcccaatc ctcatcaacc
    41041 tcaatgacaa gcctctctac atcatgggct taaaggacaa tgctggcttg gtcaaagagt
    41101 acgccctggt agacgcagtc gagtaccaaa atgttatcgt tgctactaca gtggaagaga
    41161 tgctcagcaa gtatgccaat aaaaacgacc ttgaaattga caatgcaacg acagaaagca
    41221 tcaagggagt agtagcagac ctcaaatcag ctgttatcaa gggagacact gtctacttct
    41281 ttaaagttga tggcaagata tacaaggtca aggcttcagt atccgatgac cttccttacc
    41341 ttgaaaatgg taaaaccttc gaaggtcaag taggaaaaga caattatctc aagaccttta
    41401 aagtacaata atactcttcg aaaatctcta gctctatctg caacctcaaa acagtgtttt
//
LOCUS       DAVKBC010000014        38561 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVKBC010000014 DAVKBC010000000
VERSION     DAVKBC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38561
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.014"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..734
                     /locus_tag="VWX64_000857"
                     /pseudo
     CDS             1..734
                     /locus_tag="VWX64_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(850..1653)
                     /locus_tag="VWX64_000858"
     CDS             complement(850..1653)
                     /locus_tag="VWX64_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU9190365.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1930..2685)
                     /locus_tag="VWX64_000859"
     CDS             complement(1930..2685)
                     /locus_tag="VWX64_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU9190366.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2755..5406)
                     /locus_tag="VWX64_000860"
     CDS             complement(2755..5406)
                     /locus_tag="VWX64_000860"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU9190367.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRVLEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLVGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNDLAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(5399..5977)
                     /locus_tag="VWX64_000861"
     CDS             complement(5399..5977)
                     /locus_tag="VWX64_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9190368.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5977..6537)
                     /locus_tag="VWX64_000862"
     CDS             complement(5977..6537)
                     /locus_tag="VWX64_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190369.1"
                     /translation="MARTELSDKIETERLVLRVRTVADAEDIHAYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIAGSVDFNHRHEDDVLEIGY
                     TLPPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEVI"
     gene            complement(6524..6973)
                     /locus_tag="VWX64_000863"
     CDS             complement(6524..6973)
                     /locus_tag="VWX64_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEU9190370.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQISILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPEFLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7385..7780)
                     /locus_tag="VWX64_000864"
     CDS             complement(7385..7780)
                     /locus_tag="VWX64_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU9190371.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7876..8130)
                     /locus_tag="VWX64_000865"
     CDS             complement(7876..8130)
                     /locus_tag="VWX64_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU9190372.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(8140..9474)
                     /locus_tag="VWX64_000866"
     CDS             complement(8140..9474)
                     /locus_tag="VWX64_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU9190373.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYEYMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9474..9707)
                     /locus_tag="VWX64_000867"
     CDS             complement(9474..9707)
                     /locus_tag="VWX64_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU9190374.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            9738..9812
                     /locus_tag="VWX64_000868"
                     /pseudo
     CDS             9738..9812
                     /locus_tag="VWX64_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10169..10351)
                     /locus_tag="VWX64_000869"
     CDS             complement(10169..10351)
                     /locus_tag="VWX64_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190375.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(10353..11132)
                     /locus_tag="VWX64_000870"
     CDS             complement(10353..11132)
                     /locus_tag="VWX64_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190376.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            complement(11410..11760)
                     /gene="rbfA"
                     /locus_tag="VWX64_000871"
     CDS             complement(11410..11760)
                     /gene="rbfA"
                     /locus_tag="VWX64_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU9190377.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(12011..14803)
                     /gene="infB"
                     /locus_tag="VWX64_000872"
     CDS             complement(12011..14803)
                     /gene="infB"
                     /locus_tag="VWX64_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU9190378.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(14820..15119)
                     /locus_tag="VWX64_000873"
     CDS             complement(14820..15119)
                     /locus_tag="VWX64_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU9190379.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(15112..15405)
                     /locus_tag="VWX64_000874"
     CDS             complement(15112..15405)
                     /locus_tag="VWX64_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU9190380.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(15427..16563)
                     /gene="nusA"
                     /locus_tag="VWX64_000875"
     CDS             complement(15427..16563)
                     /gene="nusA"
                     /locus_tag="VWX64_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU9190381.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(16607..17086)
                     /gene="rimP"
                     /locus_tag="VWX64_000876"
     CDS             complement(16607..17086)
                     /gene="rimP"
                     /locus_tag="VWX64_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU9190382.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(17212..17847)
                     /gene="trmB"
                     /locus_tag="VWX64_000877"
     CDS             complement(17212..17847)
                     /gene="trmB"
                     /locus_tag="VWX64_000877"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU9190383.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(17844..18638)
                     /locus_tag="VWX64_000878"
     CDS             complement(17844..18638)
                     /locus_tag="VWX64_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU9190384.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(18800..19411)
                     /locus_tag="VWX64_000879"
     CDS             complement(18800..19411)
                     /locus_tag="VWX64_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9190385.1"
                     /translation="MEFFDKFHALCFGFLVLIIVIIVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            complement(19562..19795)
                     /locus_tag="VWX64_000880"
     CDS             complement(19562..19795)
                     /locus_tag="VWX64_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190386.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(19837..20526)
                     /locus_tag="VWX64_000881"
     CDS             complement(19837..20526)
                     /locus_tag="VWX64_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9190387.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(20558..20791)
                     /locus_tag="VWX64_000882"
     CDS             complement(20558..20791)
                     /locus_tag="VWX64_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family peptide pheromone/bacteriocin"
                     /protein_id="HEU9190388.1"
                     /translation="MDTKMMSQFSVMDNEMLVRTEDGDVSDIYRGYANQRSPFASYPS
                     ILKNSGPFPVSGYCLRGYHDRGYIGAGFHLCGI"
     gene            complement(21035..21238)
                     /gene="blpN"
                     /locus_tag="VWX64_000883"
     CDS             complement(21035..21238)
                     /gene="blpN"
                     /locus_tag="VWX64_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU9190389.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(21254..21484)
                     /locus_tag="VWX64_000884"
     CDS             complement(21254..21484)
                     /locus_tag="VWX64_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU9190390.1"
                     /translation="MNTKMMSQFSVMDNEMLDRIEGGIFGVDDALFWAGLGTAICAAS
                     GVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            21774..22361
                     /locus_tag="VWX64_000885"
     CDS             21774..22361
                     /locus_tag="VWX64_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU9190391.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            22354..23931
                     /locus_tag="VWX64_000886"
                     /pseudo
     CDS             22354..23931
                     /locus_tag="VWX64_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            23942..25303
                     /locus_tag="VWX64_000887"
     CDS             23942..25303
                     /locus_tag="VWX64_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU9190392.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEITPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLETTTDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            25360..25515
                     /gene="blpC"
                     /locus_tag="VWX64_000888"
     CDS             25360..25515
                     /gene="blpC"
                     /locus_tag="VWX64_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU9190393.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(25560..26900)
                     /locus_tag="VWX64_000889"
     CDS             complement(25560..26900)
                     /locus_tag="VWX64_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9190394.1"
                     /translation="MYIFWIILYTLITNGLEIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMIGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDVYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(26913..27650)
                     /locus_tag="VWX64_000890"
     CDS             complement(26913..27650)
                     /locus_tag="VWX64_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9190395.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(27655..27993)
                     /locus_tag="VWX64_000891"
     CDS             complement(27655..27993)
                     /locus_tag="VWX64_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9190396.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVRYARRRYRE
                     IRQKWLKEGE"
     gene            28268..28597
                     /locus_tag="VWX64_000892"
     CDS             28268..28597
                     /locus_tag="VWX64_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU9190397.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(28765..29814)
                     /locus_tag="VWX64_000893"
     CDS             complement(28765..29814)
                     /locus_tag="VWX64_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190398.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(29811..30542)
                     /locus_tag="VWX64_000894"
     CDS             complement(29811..30542)
                     /locus_tag="VWX64_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190399.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            30610..31020
                     /locus_tag="VWX64_000895"
     CDS             30610..31020
                     /locus_tag="VWX64_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU9190400.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            31030..31317
                     /locus_tag="VWX64_000896"
     CDS             31030..31317
                     /locus_tag="VWX64_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190401.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            31479..31718
                     /locus_tag="VWX64_000897"
     CDS             31479..31718
                     /locus_tag="VWX64_000897"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190402.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(32040..33176)
                     /gene="dnaJ"
                     /locus_tag="VWX64_000898"
     CDS             complement(32040..33176)
                     /gene="dnaJ"
                     /locus_tag="VWX64_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU9190403.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVYGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(33381..33635)
                     /locus_tag="VWX64_000899"
     CDS             complement(33381..33635)
                     /locus_tag="VWX64_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190404.1"
                     /translation="MLVTVERNGNVIYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHIC
                     QELHLYKTQDPHYNKFEFDLAKRSLKITTRDNTTIFISNE"
     gene            complement(33747..35570)
                     /gene="dnaK"
                     /locus_tag="VWX64_000900"
     CDS             complement(33747..35570)
                     /gene="dnaK"
                     /locus_tag="VWX64_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU9190405.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(36000..36524)
                     /gene="grpE"
                     /locus_tag="VWX64_000901"
     CDS             complement(36000..36524)
                     /gene="grpE"
                     /locus_tag="VWX64_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU9190406.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSKLDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(36551..37585)
                     /gene="hrcA"
                     /locus_tag="VWX64_000902"
     CDS             complement(36551..37585)
                     /gene="hrcA"
                     /locus_tag="VWX64_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU9190407.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(37749..38258)
                     /locus_tag="VWX64_000903"
     CDS             complement(37749..38258)
                     /locus_tag="VWX64_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU9190408.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
BASE COUNT        11468 a         8572 c         7046 g        11475 t
ORIGIN      
        1 cagataagga ccaagagctt aaagctgaaa ttcaatccat ctttatcgaa cacaagggaa
       61 attatgctta tcgctgtatt catttagaac taagaaatcg tgcttatctg gtaaatcata
      121 aaagagttca aggcttgata aaagtactca atttacaagc taaaatgcga cagaaacgaa
      181 aataaaggag acgttggtaa gaaggcagag aatctcattc aaggccaatt tgaaggctct
      241 aaaacaatgg aaaagtgcta cacagatgtg acagaatttg ccattccagc aagtactcaa
      301 aagctttact tatcaccagt tttagatggc tttaacagcg aaattatcgc ctataatctt
      361 tcaacttcac ccaacttaga acaagtacaa acaatgttgg aacaggcatt cacagagaag
      421 cactacgaga atacgattct ccatagtgac caaggctggc aataccgaca cgattcttat
      481 catcggttcc taagagtaag ggaattcaag catctatgtc acgcaaggga aacagccaag
      541 acaacggtat gatggagtcc ttctttggga ttctgaaatc ggaaatgttt tacggttatg
      601 agaagtcgtt tcagtcgctt aagcaattgg aacaagctat tgtagactat attgattatt
      661 acaacaacaa gagaattaag gtaaaactaa aaggacttag tcctgtgcag tacagaacta
      721 aatccttcgg ataaattatt tgtctaactt tttggggtca gtacacctaa aactttgatg
      781 atatacgttt tcttgtgaga atatttactt catttttgcc taaaattcaa tgtttactca
      841 gtatttggat tatgaaaaat cgaggtctaa atctagatac attttttctg aagacaaatc
      901 attttgacca ccgagcaaga gattttcaaa aaaagctgtt aaaaactcag aacgtcgctg
      961 taaaatcttt gcattatcta ataccaaggc atcacgaaaa tatttggaat gttgctgaaa
     1021 tggtgtatta tcaatatcaa aaccaaactc acgaagatac tgaatcaaaa agaccgttac
     1081 tgtccgagtg tttccttcgc gaaatggatg aatctgccag attcctgaaa taaaatgctg
     1141 gatttgttta accacatccg cctgagttag tgtcgcatat gcaacttgtt tttcctgatt
     1201 aaaatcataa tctaaggtca tttgaatcat ggagtaatca gagtacacaa cactttcacc
     1261 attcaaaaca ggttcattct ttgtgatatt ggtctgacga aattgcccca ccggaataga
     1321 gggttcaaat atatcttgaa acaactcctt atgaatagca agtaaggtcg caggactaaa
     1381 gctaaagcct cttcgagaca atagttctac aatacgtaga gaaaccaagt ctgcctcttc
     1441 cgtacttgca tcaatagtat ggtgataagc cgttgcatcc tcataaacct gctcataagt
     1501 cagttctccc cgggactgtt tctcagccaa agattccata tacgctgatg gcactagatt
     1561 gtcaactttc tgcagaccaa aacctatccg ccataaatca cgcttcgctt cataagacaa
     1621 gtttggattg tcaatgttgt aagttggttg catagaaata tcctttcaat tgtttttctt
     1681 cattaccagt aaatcacgaa attggttgga aactggctta aactataaaa agtcctcaca
     1741 ataggttcta tgatatatat atatacttca tgtaaataat aaaagagtta taatcagcac
     1801 tactgataaa ttcaataccg atttcgccat cttaaaactt agtcaaacga ataccgttga
     1861 tttccagttc attaagtcgt tgacctgtca agacttctcg ttccttcaac tggaaaagtt
     1921 aagggggaac taatacaaat cctctacgct tctatattca atgatttcat ttttgataat
     1981 attcttttta aactcaaaat gttttaaagg attatcgatt aacactaact ttggaatatc
     2041 atctagattt gtgaccaagg ataaaataaa atccgattga aactccttga ctttttcaaa
     2101 ttcttttgca gttaaacgca cacgcccctt agattttcgg atacctttta cttcggcaag
     2161 gtaagaatac tcttggacat ctacctgaaa gtcatatcca tcaccataaa gacgggcatc
     2221 ggttaactgt ccaccttgga atttttcttc tttatcaaaa tgaaggataa aataattctc
     2281 agcctccatt cccgtttcct gtagacgttt gaatttagtt cgaactattg gtttttcaac
     2341 gatggttatg cctgttttct tcccttcact ggcaagtaac attttaacta tttcagcata
     2401 actatgaaca tcttcatttc caaacatcat atcaattaaa tctttacgaa aacgataaac
     2461 ttcagctttc tgccaccaac cttttcgatt attgtcaaaa taaggatcaa ataaatccat
     2521 tctatttttt acaactccag ttgtttcagc aattcccaga gaaaccacat agcgataaaa
     2581 ctccgacttg ctagagcatt gaaattcttt tataaaaagc ttgtcaaact tggcaagacc
     2641 gtagccaatt aaatttaaca attcataatg agggtgtttg gacatcactt tctccatcaa
     2701 tagatattga tttcattata ccaaaaaaca cggctcatca ccgtgtttct gtgtttattt
     2761 caccaacttc ttcatctcat caatacgtgc tacggtcaca tcatacttgg cttggtagtc
     2821 ggcttgtttg tctttttctt tttggacaac ttctggttta gcgttggcga cgaagcgttc
     2881 gttgctgagt tttttgccaa ccatgtcgag ttctttctgc catttggcaa gttctttttc
     2941 cagacgtgcc aattcttctt cgacattcaa gaggtctacc agtggcaaga agatttcggc
     3001 tcctgtaata acgcttgaca tagccagttc aggtgcaggg atggttgatg cgatttccaa
     3061 gtgttctgga tttgtaaagc gtttgatgta gttgacattg ctgttaaaga aggcttccaa
     3121 gtcactatcg ctagtcttaa caaggatggt gataggtttg cttggtgcta catttacttc
     3181 cgcacgcgca ttacgaacgg cacggatcaa gtctttgaga ctttccacac cagtgtgggc
     3241 agcaaggtcc tcaaaggctg ggttgacagt tgggtatgct gctgtcacga tagagccttc
     3301 agcgtactga ccaaagattt cttctgtcac gaacggcatt attgagtgaa ggagacgaag
     3361 gattttatcc agcgtataga ggagaacaga tcgagtaatt accttatcgt cttcattgtc
     3421 gctgtaaaga acttccttgg tcaactcaac ataccagttg gcaaattctt cccaaatgaa
     3481 gttgtaaagg atatgaccag ccacaccaaa ctcgaactta tcaaagtttt cagtaacttt
     3541 tgcaatggtt tcgttgagat tgtggagaat ccagcggtcc gtcacattac cagcctcacc
     3601 tgttgcaact tttgtgacat tgtcatgcgc cacatccagc gtcaaacctc cattgttcat
     3661 gaggatatag cgagaaatgt tccaaatctt gttaataaag ttccatgaag catccatttt
     3721 ctcataagag aaacgcacgt cttgtcctgg cgcagaaccg tttgaaagga accatcgaag
     3781 ggcatcggca ccgtatttct cgataacatc cattgggtca atcccgttac cgagagactt
     3841 agacatcttg cgtccttgct cgtcacgaat gagaccgtgg ataaggacgt tttggaatgg
     3901 ttgacggcct gtgaattcca atgactggaa gatcatacga gacacccaga agaagatgat
     3961 gtcgtaacct gttaccaagg ttgaagttgg gaaataacgt ttaaagtctt ctgagtcgac
     4021 ttcaggccag cccatggttg aaaatggcca gagggcagaa ctgaaccaag tatccaagac
     4081 gtcttcgtcc tgagtccatc cgtcaccttc tggagcttct tcgccgacat acatttcacc
     4141 atcagcattg taccaggcag ggatttggtg accccaccag agctgacgag agataaccca
     4201 gtcgtggaca ttttccatcc attgaaggaa ggtatcgttg aaacgaggtg ggtagaattc
     4261 gaccttgtcc tctgtgtctt ggttggcaat ggcgttctta gccaattggt ccatcttgac
     4321 gaaccattga gtagacaagc gaggttcaac cacaacacct gtacgctctg agtgaccaac
     4381 actgtggaca cgtttttcga ttttgacgag ggcaccgatt tcttccaact tagcaacgac
     4441 tgccttacga gcttcaaaac ggtccatgcc tgaaaattca aaggccaagt cattcatggt
     4501 tccgtcgtcg ttcatgacgt tgacttgtgg caagttatga cgttggccaa ccaagaagtc
     4561 atttggatcg tgggcaggtg tgattttcac gacaccagta ccaaactcag gatctgcgtg
     4621 ctcatctcca acgattggga tgagtttatt agcgattgga aggatgacat ttttaccaac
     4681 caagtccttg tagcgcgggt cttctgggtt gaccgcaacc gcaacgtccc caaacatggt
     4741 ctcaggacga gttgtagcaa cttcaaggac gcgtgaacca tcttccagca tgtaattcat
     4801 gtggtagaag gcaccttcca catccttgtg aatcacctca atatcagaaa gggctgtgcg
     4861 agctgctggg tcccagttga tgataaactc accacggtag atccagcctt tcttgtaaag
     4921 gtccacaaag accttacgaa cagcttttga caaaccttcg tcaagagtga aacgctcacg
     4981 agaatagtct acagagagcc ccatcttgcc ccattgttcc ttgatagtag tggcatattc
     5041 gtctttccat tcccagactt tcgtcaagaa agactcacga ccaaggtcat agcgggaaat
     5101 gccctcacca cgcaagcgct cctctacctt agcctgagtg gcaatccctg cgtggtccat
     5161 cccaggaagc caaagggtat caaaaccttg catgcgtttt tgacggatga taatatcttg
     5221 caaagttgta tcccaagcgt gaccaaggtg aagtttacct gtaacgtttg gtggtggaat
     5281 aacgattgaa taaggcttag ccttttgatc gcctgaaggc ttgaaaacat cagcatcaag
     5341 ccatttttgg taacgaccag cctcaacctc ggctggattg tatttagatg aaagttcttt
     5401 agacatgtgt gtgtcctttc tctattttgt ttattttatt ttgaatctgc ttagcagctt
     5461 cttctgcaga caaattcgta ttatttattt taaagtagtg gtgcaactca ttcggttgat
     5521 attgggaatt taattgaagt gtttcagcgg tctctaaaat ttctctttca gatacctcaa
     5581 tatgtcgttt taagggtttg tgctttaatc gattctccgt tcgatttcga cgtatgcact
     5641 cttcaagact tgtttccaac tcaacaaaaa gaatctcttg atgataatca tccaacaaat
     5701 tctgaatttg ctttaaatat atcagatgat actgatttga aaaatcaatt acatctgtta
     5761 aaattactga tcgctgattt cttgcacttg ctccaaggaa tgaaaaagtg attccacgaa
     5821 caaattccca catttcctct gtatagtcct gatagatttc tagtgcaaaa tcaatggctt
     5881 gatggttata aaatagggta gcatccgtca gtcgagataa ttcttgacca atggtcattt
     5941 ttcctgatgc tggagcacca atgatgaaaa gatgcatcaa atcacctccc actcgctctt
     6001 cagcaagcca tatatcagac tgtcacagcg gtttccttga acatcctttc ggtctcggat
     6061 gcgagcttcg agggtaaagc caagcttttc cgcgactcgt tgactttgaa ggttatatcc
     6121 aaagcaagtt agttcaatct tgtgaagacc caaatcttta aaggctaagt caatcaaggc
     6181 acgcgcagct tctggcacat aacctcgccc ccaatagtct gggggtaagg tatagccgat
     6241 ttccagcaca tcatcttcat ggcgatggtt gaaatcgaca gagccagcga tcttatccgt
     6301 tcctttgacg acaatcccgt agcctgctgg gagattttcc ttttgattac gctccggaag
     6361 aatgtgctcc agataataaa tctcatcttc caaggtcttg actggaggaa aacctgctgg
     6421 ataggcgacc tctggcaaac tagcgtaggc atggatatcc tcagcatccg ccacagtacg
     6481 gactcgtaaa acgagacgtt ctgtttcgat tttatctgac agctcagttc ttgccatcct
     6541 tcttcctcgc ttttttgatg aaactgccct tcatatctac acgcttgtcc agatagcgat
     6601 aaacgcgctg atatccatct cccatgaaat aggttggggc aaacagttga tttttaaaat
     6661 gtcccttttc atccaggaat tctggggcaa caagtcgctc aagaatcttg gcaaagatgt
     6721 ggcaaatacc gtcttcctca acaatcctat ctacccgaca atctaaaaca agtggacagg
     6781 cgtctaaaat agaaatctga gttcgttcag aaatttcata atgcactccc aaacgttcca
     6841 atttctcctg atgactgata aaaccagcct gctccatcgc aagcatagaa gtttcatcag
     6901 aaatattcac agtaaatttt tgatactgtt tgatctgctc tgcggcattc tctctcgcaa
     6961 cgactccaat cacaacccaa tctcctagac tataagagga actacaggtc gtgatgttat
     7021 agccaaaatt ctaatcttga tatcctaaaa taaaaacagg aaaaccataa tatagtttat
     7081 tagttttaaa tgattgtttt ataacaacct cctttgacta agacacaaaa gaaaagccct
     7141 gccatctaca tgacagggac gaatgtgttt atccgcggta ccacccaatt tcgggccaag
     7201 cccgcatctt tagtctttaa aataaaaaga cagaaatatt tcattttttc agtcattagc
     7261 aaccagtttt gacacatttg tggacttctc agcgccgcca ctttctgtaa aatgtgggat
     7321 tcaaaacacc tctaatggct ctattgtagc aagtttttct cggaaatgca aggctcaaga
     7381 aaaattactt gaacttgatg ccattttctt tcaatttctt gatggtagct gggccgattc
     7441 ctttcaaggc aaggagttct ttttcagtcc agtttttgaa atctgaagca gacttgattc
     7501 cttcatcata gaaagtcttg gcacgatcaa gtggaagtcc acccaagttt gctgcaaaat
     7561 cttctacaga attagctact ttttgagctt gctctttggt agcttctact gcttgttcaa
     7621 cttttttaga aacagcctta ccagctgcgc ttgctgactg ttctgcacgc ttcacgactt
     7681 tttttgtctc atctacaacc ttagtcacag tacttgaaaa ggcacctgcg cgacggaggc
     7741 catttcgtaa ttgtttttta cgattgagtt tctttgacat gataaaatcc tttcaataaa
     7801 aaatccctgc tctgacaagg atttaacata aacattctat caagatttta gtgaaaaatc
     7861 aagaatcttt ctcgtttaat aatttcgctc accaaacaag ccttctggca aatcatggaa
     7921 tcccttgcct actttgaagt tttcaaactt accaagcaag aactgataag catccaaacg
     7981 actctcatag cgaatcatgg catctttggc acgctcgtcc tggtcttctt cgtaaacttt
     8041 ttggctttcc ttgtgcgcca tgtcgttaat catgatttgg gtattgaccc aagcttcaaa
     8101 ttccttcata aattcttgtt cgtaactcat tttttctcct tattctaatc cacgaaaata
     8161 gtccgtatca atctcacggt agggctggat atcctgaaca tactccaaca ctccttggaa
     8221 ttctccgtct tcatcgtgta ctgcagcata ggtgatgtgg acaaacttac ctcgcgactc
     8281 agacttgaac cacatttcat acttgtcttt gcttccctca cgaagtccct tcatgatagc
     8341 cttgaccttg tccaaatact taggcggatg acagagttcg acattgcgcc cgacttggga
     8401 cggcgtccgt ttgaaaatca tctcatcagc tggcgtattg tcattgtaat actggaaaat
     8461 atcttcttta ttgacaaagg taatctccat agggaggtga ttgaggatga gattggcctg
     8521 ctcgactgaa agatagccat taccaaaagc ctgttgacta tggcggtcca gcacagcttc
     8581 cttttcctta ggggtaaagg taatggtaaa atggccttct ggcgtatcta tgacttgttg
     8641 aacttgacct tctgccgtat ctagctgtac aggctcctct gcaatctttt cctcaataaa
     8701 gctctgtcgt tctggcaccc atttctctga cggacggatg atggcatagc cataggcatc
     8761 gctctcctcc gcaatctgaa gccagtcatc ctgagtaaaa gactcaagga gaatcatgag
     8821 gaggatggac tcttccttga aaatcatact ttcaaactct gtcgcaaaag cttcaaaagc
     8881 ttcctttaca ctgctaattg acacttctgg tagtgacttg gctgtcgtta gagctgtttg
     8941 aaagagttcc ctaatctgat catccactcc ccacataact ttgggaggtg aatcgtgtcc
     9001 atagcgctcc atgataggaa agaagagttc ttccttacgt tggtaatgga tgtcaaattg
     9061 acccacaagt cccatctgac gcaccaaacc cttacgcatc tccgccagca tttcctcgtc
     9121 ttccatatac tcataggtat ctaacaatct acgaatgcga atcaaggccg cacggagagc
     9181 cagattttct tctttgaaga cacgaactgg gtgacctgga tgctcagtat ctgaaacttc
     9241 gacacctttg atagcatttt taaaaagatt ggcatggaca tcacagagtt ccataacatc
     9301 ttcaaaggtg acacctgagt ctgagttcat cagctcgtgc tccataaggg aaatctcgat
     9361 ggctgagaca cccgcaaagg tcgcatcaaa gcgctcttga accgactcag gagaggcgcc
     9421 attgtgcaat tctaacaaaa tatcccgtag gacatgaatc cgttcatctg ccattagtct
     9481 aatccaatca cttcgtagcc attcgcttcc agtgtgcgta caatcttgtc cataggagtt
     9541 cctgctagct tagaaccctg tttaagtgat actttacgac caactgtatt gcgcattaag
     9601 ggattggcaa ggggtttaaa acccaactcc actagaattt ccaagacttc tggatgcttg
     9661 tccaccactt ctgcaacagg aattgacaca tcgatgatat tgtccatgac gacctccatt
     9721 gtatgttcta atactcaatg aaaatcaaag agcaaactag gaagctagcc gcaggttgct
     9781 caaaacagtg ctttgaggtt gtggatagaa ctgacgaagt cagctcaaaa caccgttttg
     9841 aggttgtgga tagaactgac gaagtcagta acatatatac tgcaaggtga agctgacgtg
     9901 gtttgaagag attttcgaag agtataaaat gattttactg cttatattat accatatgga
     9961 aagagaataa aaaactagca gtggagttcc tgctagttct ctgcgacttg gattaccatc
    10021 tagataagtt taaagagcca atccaatatc ttaaacacta tcttgtaaaa cagcaattgg
    10081 actgcaaaag agatgatcat ccaaaagaat ttcacaatcc caataatcgg tttgataaaa
    10141 ataatggcaa gaagtcccca gaaaaatttc attttttatc ctctggctta atgagccacc
    10201 gagccgtatc cattagctta tctgcaataa agagttttcc cagaccaaca acgacatggt
    10261 catctttctt tatcgttttc attactttta caccttgcac ggtcaaaaag taattaccat
    10321 aaattttagc tagagttttt atgagtccca tattactctc cttcgatgat ttcagcctct
    10381 tttcggattg tttcaacatc ttcttgatat tgaacttcac tatagttaac tagcttggac
    10441 aattctttct gcaagctttc acccatcggt ttcatagttg caaaggttaa accacctgaa
    10501 atgataccac ccaagatagg aataaatttc cccattcctt tggccagccc tcccttggta
    10561 agattcacac caaatattct taagactttt ttcaaaatag gataccaaag cgtctttgtt
    10621 aaagctttat taggtactgt tttcattacc tgtttggcaa ttgttatacc accagcacgt
    10681 agcaaagcag cagttccatt cacccccaac atgacgccta gataaagcaa aagggtattt
    10741 tgagcatctt cactcaactc atcgcgtgaa gcccaaagat cctcataacc ataaatataa
    10801 cctaattctt gggccaattt cagagagaaa ccataaaatt gagccacatc agctggaatg
    10861 gtaattgcca tagcaagccc tccaggtaat cctgccaaaa cagaagtccc actcgctaat
    10921 aaaacattat ccctaataca ggcattagcc actcgatcta agatttcttg agataagaga
    10981 gacgttggac cttgttccaa taaggtagga atgtcctgtg gacccaattc tttggaaaac
    11041 ttatccacta aaaatttcga acgatcaacc ttaacaacag gtagtttcac cacttgttgc
    11101 aatacttgca tagctaagtc ttgttcagcc atatacaaac tccttatttc ttttttgcac
    11161 cttatcatat tatatttcct acaaaaaagc attttctaat tagataacat taaaaaatac
    11221 agaacccctt ttttatagtg aaatgaaaca agaacaggac aaatcgatca ggacagtcaa
    11281 atcgatttct aacaatgttt tagaagtaga ggcgtactat tctagtttca atatatttta
    11341 aaagaatatt tttccatttc aaattcaacc tattttcctc caccaaaaaa gaggggcaac
    11401 ccctcttctt tagttcttat ccagattgcg tagcatctcg tcaatcttgt ttccatactc
    11461 gatggactcg tctttgacga aggtcaaatc tgggattttg tacaatttca aattgcgacc
    11521 aagttcacgt ttgatggtac cagttgcttt ttcaagcccg atttgggctt tttggttatc
    11581 cgaagcaagg ttactcaaaa tggtgtaata aaccttggca acagacaagt cacccagcat
    11641 ctgaacatct gtgatggtca caccttggac acgtggatca cggactttct tttgcaaaat
    11701 ctcattgact tcacgcttga tttccatgcc cacacgatct gtacggaaat gatttgccat
    11761 gatattcctt tctctacttt gaaccaaaag ctaggccagc agacctagct attttaaact
    11821 tcttgatttt cagtttaaat tgaaacgaag ttcaatttga agtcatctgc ttctttcgcc
    11881 gtggtgaaag tgatggaact gatttatcag tcccatcaca ggggattttt gagaccctag
    11941 gctcaaaaat aagcaatgaa accatcggtt tgcttgcgtc cctcaccacc taagaaagga
    12001 gcaaaaaatc ttatctcttg atttcttcca tgacatacgc ctcaatcaca tcatccatct
    12061 taatatcatt gtagccgtcg atcatcaatc caccttcacg accgtttgtc acttctttca
    12121 cgtcatcttt gtagtgtttc aagcttgcga gttcgccatc atagataacg acaccatcac
    12181 ggataacacg gactttagag tcacgggcaa ccttaccgtt gataaccata aatccaccga
    12241 tagttccgac tttagacacc ttgaaggttt cacggataac cgcttcacca ataacttttt
    12301 cttcaaattc tggatcaagc atccctttca tagcttcttc catctcttcg ataaccttgt
    12361 agataatgct gtgaagacgg atttccacat cgtcagcttc tgcttgttga cgagcttgtg
    12421 gtgtagggcg tacgttgaaa ccaacgataa aggcatttga agcttcggca agggtcacat
    12481 ctgattcgtt gatagcaccg accgctgagt ggacgatagt cactttgaca ccttccacgt
    12541 caatcttttg aagtgaggca gaaagggctt caacagaacc ttgtacatcg gccttgatga
    12601 taacattaac agatttgagt tccccagctt taagggtatc aaagaggttt tcaaggctaa
    12661 cacgttgggt agcttgacgt tgtttcatga gggcacgttt ggcacgctct tcacctgctg
    12721 cacgcgcaga tttttcatcc tcgtaaacgg caaagtggtc acccgccatc ggtgcttcgt
    12781 tcaaacctgt gatagagact ggtgttgatg gtccagcaac tttaacacga cgaccaaggt
    12841 cgttggtcat agcacggaca cgaccgaagg tatttccgac aacgattggg tcttgaacat
    12901 tcaaggtacc ttgttgtaca agaagggttg cgaccgcacc ttttccttta tccaagcgcg
    12961 cttcgataac cgtaccgatc gcacgaactg ttgggtctgc tttgagttct tggatttcag
    13021 ccacaagaag gactgtttcc aacaattctt cgatattttg gttgaattta gccgagattt
    13081 caacaaattc agaatctcca ccccaagcgg ttgacatcac accatgctct gccaattcac
    13141 cgataacgcg ttctgggtta gcacctggtt tatcaatctt gttaatagct acgatgattg
    13201 gaacgttagc tgcttttgag tggttgatgg cttcaatagt ctgaggcata accccgtcat
    13261 ctgccgctac gaccaagatc gtaatatcgg taacagaagc accacgcgca cgcattgatg
    13321 taaaggccgc gtgtcctggt gtatcaagga aggtaatctt cttaccattt tccacgattt
    13381 ggtaggcacc gatatgctga gtaataccac ctgcttcacc tgtcgcaaca cgtgagttac
    13441 gaagagtatc caaaagggtt gttttaccgt ggtcaacgtg tcccatgata gtaacaactg
    13501 gtggacgctc aaccaattca tcttcattga gataaccatc ttcgacaaag aaacgttcga
    13561 tgtcagcatt atccacttca accttttgtt tggcttcgat accgtaatcc accatgagga
    13621 gttcaattgt ttccccatcc aaggattggt tttgtgtggc catgacaccc atcatgaaaa
    13681 gtttcttaac aatttcagct ggttcacgtt tgatacgttt tgcgatttcc gcaacggtca
    13741 taccatctgt atattcaaat tctgttggca attcatggaa tttacgctcc gtaacaggtt
    13801 ttggagtctg attacggttg ttcttgttat tgcctttttt gttctttttg ttgttattcc
    13861 agttactatt cttttgattt ctcacttgat tttgactact tcgattcttt tgttgttttc
    13921 taggaccatc ttcttcatga tcataatcgt cacgattttt gtctggtcga gcttgttttt
    13981 tacgacgtgt atccactgca ggttcttttt tctcagggac gacttcaacc actgcttgaa
    14041 cttgctgtgc ttgttcagct aacttagccg cttcttcaaa gatttcctct ggttccttgc
    14101 gtttgttagc ttgagccaag gcttctttag cagcctgata ctgcttgaag cgttcctcac
    14161 ttgaacgagc gtactctgca ttttgctctg cttttagggc tgctgcacgg gctttaaagt
    14221 caatacgtgg agccacttga tttgaacgtt tgtcctcttg ctgacggcgc tcatttctac
    14281 gtttttgctg accttgctgc ttcttagctt ggtcattaaa gcgacgattg tcgcggttgc
    14341 tttgaccttg ttttccacca ttacgtccgt cgtttttctg acggtttccg ttttgttgtt
    14401 ggtcacggtt attgccctta ttttgcttac gtcgttctgc ctgctcttta gcacgggctt
    14461 cacgctcagc cttgaaatta cggctttgcg gtttcgctgc tactttttct gttttcggag
    14521 caactggctc agccggtttt gcctcttcct tagctacagc tggtttagct ggctcagatt
    14581 tttcggcttt cttttctgca cttacttttg gtgctgcagg ttttgcttct actttcggag
    14641 cagctgcagg cttaaagctg gcagcaattt ttgcagcgac agcttcttcc acacttgatg
    14701 agtggctttt cacatccaag cccaactctt ttgcacgcgc tacaacttct ttactttctt
    14761 ttccaagttc ttttgcgatt tcgtacaatc ttttcttaga caaatcatgt cctcctcttc
    14821 tattccataa gagacctcat tttctttgta aatccagcat ctgttacagc caaaaccttt
    14881 ctcgatttcc cgactgctat gcttaattcc agtgttgaaa acacggttac aatttctact
    14941 tgataataat gacttttatc ttgaatcttc ttggtcagat tgggtccagc atcatgagct
    15001 agaaagacca acttggcctt gccgtcttga atggccttga ccaccaattc ttcacccgat
    15061 atgatgcgcc ctgctcgctg agcaagcccc aagagattac ttatcttttg cttattcaag
    15121 tcccaactct cttcttttca ctttgtgatc cacataagcg atcaactcgt cataaaagct
    15181 ttcttccact tccatgctaa agctgcggtt aaagaccttc ttctttttcg cctctagggc
    15241 ttctgcattg tctagtttga tataagcgcc gcggccattg gccttgcccg taggatcaat
    15301 aaagacttgt ccttccttgt tcttgacaat gcggagcaaa tcacgcttat caatcacttc
    15361 gttagacaca acagacttgc gcaaagggat ttttcttgtt ttcatctttc cctcctctag
    15421 cagcttttat tcttctacag tatcgttttc tacttccaac tctactgaag cagcgtcttc
    15481 catggcttca aattcgctag cagacttgat atcgatacgg taaccagtca agtgagccgc
    15541 caagcgcacg ttttgtccac gacgaccaat ggcaagagaa agcttgttat ctggaacaac
    15601 caccaaggca cgtttgctgt cgttttcatc aaagataact tggtcaacct cagcaggagc
    15661 gatggcattg tagataaatt cagctggatc tgctacccac tcgataacat cgatattttc
    15721 ttcgattggt accatgcggt catttttagc atcgtaacga gctgggtgga atttgctagt
    15781 aatcttcttg atattagcac caccacgtcc aacgattgta ccgatagcat ccacgtttgg
    15841 attgtggcta cgaacagcaa ccttcgtacg gtcacctgct tcacgagcca cgctcatgat
    15901 ttcaacagtt ccatcataaa cttctggaat ttcttgctcc atcaaacgtt tgatcatttc
    15961 tggatggcta cggctaacaa agacgttcac accacgaggg ttgtcttcaa ccttgtaaac
    16021 ataaacttcg atacgatcat gagaagcaaa aacttctcca ggaatttggt cttgttttga
    16081 caattgggct tcgatgctac caaggttgac atagataaag cggttgtcaa agcgttctac
    16141 tgtaccagac atgatttctt gctcatgttc tttgtaagta ttgtaagtga tggcacgtgt
    16201 ttgcttgcgc attttttcca tgatggtttg tttggcagat tgggctgcta cacgaccaaa
    16261 ctcagctggt gcttcttcaa acttgatttt gtctccaagt tcataagctg aattaatagc
    16321 aagagcatct ttcaagctga tttccaaacg gctatcaaat acttcatcaa caacttcacg
    16381 gacagtataa actgtaaagt cacctgtttt ttcgttgaag tcaatagcta cgctgtctga
    16441 ctgaccatag cgtctgcgat aagcggaacg aagcgactct actactgcgt cgatgatatc
    16501 ttcttttttg attcccttgt cttcttccaa aatgcggaag gcctctagca tttctttact
    16561 catgttttct tcacttttga atcctcaaaa gctatccttt ctttttctat aatttaactg
    16621 ctaaacgtgc ttttgatact aaactgtatg gaatttggac ggttttctta cgcgtcttgt
    16681 ccatatattc catagtcaac tcgtcctctt cgaaggccaa caaggttcct tcaaagacct
    16741 tttgcttatc gatggcttgg tagagcccga catggatgta ttttccaacc gctccagcga
    16801 cggcatcctt ggttttcaaa ggacgttcca aacctggact ggtaatttct aggaaatatt
    16861 gttctgggaa gggatctggc ttgatggtgt ctaggacagg actgatcatt tctgtcaagt
    16921 ctgccgtgtc gttcaaggta attccttcgg gtttatctac aaaaatactg agaatcatgt
    16981 cactgccaat ctttccatac tcgatatcca cgagttcaaa aggagcttct atgacaggtt
    17041 ctacaacttc tctgactaat tctacgattg ttgcgattgc gtccacctcc tcataagcaa
    17101 gaggcgaaga tatttccccg cctcactttt catattctta ttatcagtat agcacgtttg
    17161 ccaacctatg taaagcaaaa gcacttgtac agcctaattt taggctatct attaaaattc
    17221 tgcctcaact cggtagataa cttgcccctt gtttgagaat ttttgctcgt attctgtcat
    17281 gacattgcct tcaaaatcac tggcatgcaa atctaaccag acaccattga gtttcatgcc
    17341 atattgagaa aagctcacta aactgtactc aaacaagcca cggttatccg tcttgaaatg
    17401 aatttctcca ttttcaggca agatacgttt gaaggtatcc aaaaaggtct tgtaggtcaa
    17461 acgacgcttt tcatggcgtt ttttcggcca tggatctgaa aagttcagat acaagcgatc
    17521 aatctcaccg tcttcaaagt agtcagtcaa gtcagaacca tctacccaca agagcttgat
    17581 gttagacact ccagcttcaa gcaccttgtc caaagcgtag ctcaaaacag acttttgaat
    17641 atcaatcccg atatagttga tgtcagggtt ttgcttggcc atacctgaaa caaaggcacc
    17701 ctttccactt ccaacttcca catgaatggg attatcattg ccaaacaagt cccgccattt
    17761 tgccttggct tccaagggat tgaggaccac atactgggga tttgcctcta gtaattctgt
    17821 tgccccttta cgatttctaa ctctcatctt ctctttccat acttgtctcg gaaatgacgc
    17881 aaaccatgaa tctcccgatt gacattttct aaatcttggt tcatataata cttggaaatc
    17941 tgactcaaat aagacaattg accataccaa tacaatttac ttaataccgt ttgattgtac
    18001 ttgtaaccgt agtaggtcaa ccattccttc cactgatgtt ctgaaatata atggcagagc
    18061 atatgggcca catcaaacat gcgatcggtc aagcgaaccg aatcccaatc tactaaataa
    18121 atcaagccac tatctgtctc aatccaatta ctatgtcgta catctccatg gacaatggtc
    18181 gcatggtcct ctctaaatcc tggaatagtc tgacgtaaat cagccatcac ttcactgata
    18241 aaatgatttt tacgcaaagc atctggagcc gtttcctgcc aagactgtag taaatctaca
    18301 ggtgtttcca tggcatagcc caaacgactc aattgtgtca tcaacggacg tgagcgatga
    18361 agacgggtta aaatattgac gatttgctta cgattcatat catagggggt caatatcttg
    18421 cctgtcaacc attcttgagc acacatatca cgcccatctg ccaaacgacg actccataat
    18481 aattgtggag caatttgttc tctagctaga ccaggtagga ttggagaggt gttcattttt
    18541 acaaagatgc gcttcccatc aggatagcta cccatataag ccttgccact tttcccaggt
    18601 atgggagtca gtgttagctc attatcaccc aaatccattt ctttcctccg tataaagttt
    18661 ccttactatt ctactagttt ttggcctatt cgtcaaccac tctaacccga ttctcaaaga
    18721 aaagcctctg gagtggtttg ggttatcatt atagaaagaa aaaggtaagc acaatctcct
    18781 acttaccttt tcataatttt tataaataat ataggagtgg ccaactgttg taaaacatgt
    18841 ggactagagt agaaacccat aagttttggc tctttttata agcaaggccc agcaacaagc
    18901 ccccaagtag ataaaaaata aacgaaggga cattagaagg tccatgcatg aaagaaaaga
    18961 gagaggaagt tagcacaagc cctaaccaag aattgtcaaa aaccgcacct tgaagaagtc
    19021 ctctgaaaat gagttcctcc tggatggggc caaaaactga ggtagtcaaa atcaaagaca
    19081 gggaaattcc tctgctgact tccgccaagt gttggacccc tgagccagaa gaaacagcga
    19141 agaaatgaat ataaaccagc gtctcaagta cacttagaag aaagattgca atgaaaagca
    19201 aaagttgttt cttgcttaac atcccaaaag aaatcatttc aaactttcta gcataagcaa
    19261 cactcagcga ggttacaaga agacttacaa gaatcaatgc agattcattt tgaaaaaaat
    19321 ccccatggtt aatcgtataa ggaactataa tgacaattat tagtactaaa aatccaaaac
    19381 acaaggcatg aaatttatca aaaaactcca taaaattatc ctcctcaaca aacagacttc
    19441 ctacacgtca ttctttagtt ctagcctttc caaaacaaac cattttatac tcttcgaaaa
    19501 tcaaattcaa accacgtcaa cgtcaccttg ccgtactcaa gtacagcctg cggctagttt
    19561 cctagtttgc tctttgattt tcattgagta ttagtaacca aaatccgacc acatagccag
    19621 cccctatgaa tatagccatt aaagctagca tggaatttag gaaattaaaa accaccgcag
    19681 atacaaaggt tagcacaaaa acattaaaag caatggtgtc agaagccaag actagaatat
    19741 agggtgtcaa ccgatctaaa gttttggaat ctaggaaaaa taagtgttta tacatgatga
    19801 cctcctctat ggctgaaaag caagcctttt gtttttttac cccaagaccc tatgtagaaa
    19861 agtgagcaaa aacgggaagg tcgctacaat attattgatc acatgcaccg cataggatgg
    19921 ataaatgctc ttggtatagc gggtcaaacc agcaaagatg attccaactg ttgcaaagac
    19981 gaagatatct aacagactag gcaggcttga aaaatgaggg agagcaaata aaatagaagg
    20041 aagaagcaaa tcaagaccaa atcgcgaatg cttaaagaaa gcatgttgca gtaatcctct
    20101 atagattaac tcttccatca gtggaaccag aaagaacagg gctatataaa tacctagctc
    20161 tgcaaagtta gtcccactat aaccaatcaa tacagcccaa ccttccgcag ttgactgaac
    20221 atgtttagct gtctgaacgt taaaagagat ctggaacact accactaata ctgtcaaaat
    20281 cgaataccaa agccattttt ttcttggaat gcggaagaga taaccatggc ctgtcttaac
    20341 aagaaccaca atcatgactc caataaaaag taaactcaag atattttgaa tccagacgaa
    20401 attaccaatc tgggaagaaa attgccaata attttggacg ataagcgtca gctgagaaag
    20461 accaaatacg aaaaataagt aagagaagac tgcacttatt ttgaatagaa gttgatactt
    20521 tttcatagaa atcctccctc atttcttgta tttcagccta tattccacat aaatgaaaac
    20581 ctgctcctat ataaccacgg tcatgataac cacgcaggca gtacccactt actggaaaag
    20641 gacctgaatt ttttaatata gaagggtaag aagcgaatgg acttctctga ttagcgtacc
    20701 ctctataaat atcagagaca tccccatcct ctgtacgaac aagcatttca ttatccataa
    20761 cagaaaattg tgacatcatt tttgtatcca tatagtatat cacttttcag ttacggaaca
    20821 agtttaatat aaaaattatc aaaaaaacat aagcaataaa gagaaaaatt aatttatcat
    20881 agattagaaa taatatgaca aaacaattca atgatgttaa ttcaatagtc ttttgttttt
    20941 tatcggagat acttatggat agataaataa gataggtttg aaaagcgaag agaataataa
    21001 agaatatagc cttcataaaa tttagctttc atttttatga tgtagcggta taggctaaat
    21061 atccacaaac cactgctcct ccaattcctc ctattgcagc gccccatggt cctagaagtc
    21121 tcccatattt cactccaccc gctgcacaac ctaaagcagc aactacagct gctcctccgg
    21181 aattacctcc ataaacctca ctcagcattg tttcatttat attacaataa gtattcatac
    21241 aagtctcctt ttgttaaaat ccacccgttg cccctgttac tcctgcccaa agagccacac
    21301 caaatttagc tcctatgtat ccacatgctc ccataaatgg cgctccaaca ccactcgcag
    21361 cacaaatagc tgtccctaac cctgcccaaa acaaagcatc gtcaactcca aatattcctc
    21421 cctctatcct atcaagcatt tcattatcca taacagaaaa ttgtgacatc atttttgtat
    21481 tcatgacaaa tactcctttt ttatttttgt cttgttgtaa ctttgataag tttagtatat
    21541 catcgttttt taaaattttt catccagatc ttgaattgtc atcgaaacgt cttgaattag
    21601 cttttttatt tcaagccacc tctatttcaa gccacctcta aatgtttaaa aaaaataatt
    21661 tctaatcact tttttaccat tcaggaagtt ttaatgacta ttcaagattt cataaaatat
    21721 gaacttagtt ttatgacata atagacctat ccactatatg aaaggaattg ccaatgactt
    21781 cttataaacg tacatttgtt cctcaaatag atgcgagaga ctgtggtgtc gctgccttag
    21841 cctcgattgc taaattctat ggttcagatt tttctctagc tcacttgaga gaacttgcaa
    21901 agaccaataa agaagggacg actgctcttg gcattgtaaa agccgctgat gaaatgggct
    21961 ttgaaacaag acctgttcaa gcagataaaa cgctctttga catgagtgat gtcccctatc
    22021 catttatcgt tcacgttaac aaagaaggaa aactccaaca ttactatgtt gtctatcaaa
    22081 caaagaaaga ctatctgatt attggtgatc ctgacccttc tgtaaaaatc actaaaatgt
    22141 caaaagaacg ctttttctat gaatggactg gagtagctat ttttctagct accaaaccca
    22201 gctatcaacc ccataaagat aaaaagaatg gtctactaag caagcttcct tcctctgatt
    22261 ttcaaacaaa aatctctcat tgcttacatt gttctctcaa gcttattggt cactattatc
    22321 aatataggtg gttcttacta tctccaagga atcttggatg aatacattcc aaatcagatg
    22381 aaatcaactt taggaatcat ctcagttggt ctggttatca cctatatcct ccaacaagtc
    22441 atgagcttct ccagagatta tctcctaacc gttctgagcc agagattaag cattgatgtg
    22501 attttatcct atattcgcca tatttttgaa cttcccatgt ctttctttgc gacacgtcgt
    22561 acaggagaaa tcatttcacg gttcacagat gctaactcta ttatagatgc cttggcttct
    22621 accattcttt ctctttttct ggatgtttct attctgattc ttgtaggggg agtcttgctg
    22681 gcacaaaacc ctaatctctt cctcctttct cttctttcca ttcctatata catgttcatc
    22741 atcttttctt ttatgaaacc ttttgaaaaa atgaaccatg atgtcatgca aagtaattct
    22801 atggttagct ctgccattat cgaagatatc aacgggattg aaactataaa gtcgctcacg
    22861 agtgaagaaa atcgctatca aaatatagac agcgaatttg tagattattt ggaaaaatcc
    22921 tttaagctca gtaaatattc tattttacaa acgagtttaa agcagggaac aaaattagtt
    22981 ctgaatatcc ttatcctatg gtttggcgct caattagtca tgtcgagtaa aatttctatc
    23041 ggtcagctga ttacctttaa cacacttttt tcttacttta caactcctat ggaaaatatt
    23101 atcaacctcc aaaccaaact ccaatctgcg aaggtcgcta ataaccgttt gaacgaagtc
    23161 tatctagtcg aatctgaatt tcaagttcaa gaaaaccctg ttcattcaca ttttttgatg
    23221 ggcgatattg aatttgatga cctttcttat aagtatggtt ttggacgaga taccttaaca
    23281 gatattaatc tcacgattaa acaaggagat aaggttagcc tagttggagt tagtggttct
    23341 ggtaaaacaa ctttagccaa aatgattgtc aatttctttg aaccctacaa agggcatatt
    23401 tccatcaatc attaggatat taaaaacatt gataaaaaag tcttgcgccg tcatattaat
    23461 tacctacccc aacaagccta tatctttaat ggctctatct tggaaaactt aaccttgggc
    23521 ggtaatcata tgattagcca agaagatatt ctaagagctt gtgaattagc tgaaattcgt
    23581 caagacattg aaagaatgcc tatgggctat caaactcagc tctctgatgg agctggtcta
    23641 tcaggaggac aaaagcaacg aatagccctc gctcgtgctc ttttaactaa atctcctgtt
    23701 ttaatactag acgaagctac tagcggtctt gatgtcttga ctgagaaaaa ggttatagat
    23761 aatcttatgt ccctaactga taaaaccatt ctctttgtag cccatcgtct cagtatagcc
    23821 gaacgaacta accgtgtcat tgttcttgac caggggaaaa tcattgaagt tggtagtcac
    23881 caagagttaa tgcaagcgca aggattctac catcatctat tcaataaata aggagaatgt
    23941 catgaatcct aatcttttta gaagcgtcga gttttatcag agacgttacc ataactatgc
    24001 gacagtgtta attatacctc tttcattact atttactttc atcttgattt tctcccttgt
    24061 tgccacaaaa gaaattactg ttacttccca aggggaaatc acccctacaa gtgtcattgc
    24121 atctattcag tcgaccagtg ataatcctat ccttgctaat catttagtgg caaatcaagt
    24181 agttgaaaaa ggggacttac tcatcaaata ctctgaaaca atggaagaaa gtcagaaaac
    24241 tgccttagca actcaattac aaagacttga gaagcaaaaa gaaggacttg gaattttgaa
    24301 acaaagctta gaaacaacga ctgatctttt ttctggcgag gatgaatttg gctaccataa
    24361 tacctttatg aattttacta aacaatccca tgatattgaa ctgggtatca caaagactaa
    24421 cactgaagtt tcaaatcaag ctaatctttc caatagcagt tcatcagcta ttgaacaaga
    24481 aattacaaaa gttcaacaac aaattggaga atatcaagag ttgagagatg ctatcataaa
    24541 taacagagca cgcttaccaa ctggcaatcc gcaccagtca attttaaatc gttatcttat
    24601 agcctctcaa ggacaaacac aaggaactgc agaggagcca tttttatctc aaattaatca
    24661 aagtattgca ggtcttgaat catctatcgc aagcctcaaa attcagcaag ctggtatcgg
    24721 aagtgtagca acttatgata atagtttagc aaccaaaatt gaagtactcc gcactcagtt
    24781 tttacaaaca gcctcacagc aacaactaac cgtggagaat caattaacag aattaaaagt
    24841 acaactagat caagcaacgc agcgcttagg aaacaatacc ttaaccgctc caagtaaagg
    24901 tatcgttcat ctgaacagcg aatttgaagg taaaaataga attccaactg gtacagaaat
    24961 tgctcaaata ttccctgtca tcacagatac aagagaagta ctaatcactt actacgtatc
    25021 ttctgactat ctacctctac tagataaagg acaaactgta agattaaaac tggagaagat
    25081 tggaaatcac ggcaccacca tcatcggcca acttcagaca attgatcaaa ctcctaccag
    25141 aacagagcaa ggtaatctct ttaaattaac cgctcttgca aaactatcta atgaggatag
    25201 taaactcatc caatatggct tacaaggtcg cgtcactagt gtaactgcaa agaaaacata
    25261 ttttgattat ttcaaagata aaattttaac ccattctgat taattttcag ataacactct
    25321 ataactattt attatcttat caaaaaggag aatcataaca tggataagaa acaaaaccta
    25381 acttcatttc aagaactaac aactaccgaa ctcaaccaaa ttacaggtgg aggactgtgg
    25441 gaagatatct tatacagcct taatataatt aagcataaca atacgaaagg acttcatcat
    25501 ccaatacaac tataaaaaat aagaccgagt aacaagaact ctcggtctta tttttttcat
    25561 cattctgtag gtatcatagt aagcacctga cgaaagactt gatcttgaca ggtagtattt
    25621 aaactggcat tgggataact ttccacaatc ttcataacgg tatagagacc gacacctctc
    25681 tcctcccctt tagaactaac tccaaaggag aagatttcag aaatatctat gccctcttct
    25741 ttgatggaat tttcgatgat gaaggtctcc tgtgctccac tttttaaaaa ggcaattgaa
    25801 acatgaggtt gaccggcctc tgcactcgct tcaatagcat tatcacaaag gatagacaca
    25861 atggttagaa aatcaagcag tctcatcccc tcaacctgaa tctcttcagg aacttcgaca
    25921 ttaaagacaa tgtccttttc tctagctttt ataaattttc cagctaggag acttttgagg
    25981 gcacgatccc gaacattcac caatcggcca aggtcatatt tattgtcctg caatttttta
    26041 ctagaatcct ttaagaccaa gtcatagacc tcttttatct gctccatatc ctcctcttca
    26101 atacccagac gtaaacttgt caagaggttg gtgtagtcat ggcgaaaact ccttacttcc
    26161 ttgtaaagtt cctctatatg ccgactatag cgttccatat ctctatagcg caagacctgc
    26221 tcttggtcca gtctatcatg gagtttgtcc ttcaaatagg tatccaattt cttgataacc
    26281 cccataaaaa ataggaggta aaacactagg atgagatggc gaacagtcgt tgattgaata
    26341 ccttgctcat attcaaagta agacagactt tgtatcacca aatagtaagc ccccattatc
    26401 cagttaatct tagtcaggga cttttgaaaa cctgtatcta gaatctccct tctcaaacta
    26461 gtaaaatcat agtccaacca tttcaaaaag gctagagaaa tgaagaaatt gaaaattatt
    26521 atacataacc cagtaaatga gtagacatca tatacttgct cttgtcccaa aaatggaagc
    26581 acaaaatagg agactcctct ataaaagaga ttcaccaata tcattggaaa gagaccataa
    26641 aagaaaagga gttttttagg aagccctctt aacaataaga aagacaagcc tatgccgtac
    26701 aagggttcca taaaataaga taggtaaaca tttcctatca tatagccaat cattacaaaa
    26761 acaaaggcca acagtatctt caaaagaaag gccttaaaaa tcctctcaaa agtgagacca
    26821 attccatcta ccttaaagaa aatgacaatt tctagcccat tagtaataag tgtatacaat
    26881 ataatccaaa aaatatacat aaatttccta gttcagtgta agttattaat agcctcagac
    26941 acttccctga ccttataacg cgcgatcaga cagcttccac cattgggaaa gaaaaggagt
    27001 ttttctttct tatccaaatg caccacattt gcaggattga tgagaaaaga gcgatggcac
    27061 tgcaagagac ggggttcctg cttaaaaacc tcctctaaac tcgccgtaaa ttctagcctg
    27121 tccgtcttgg tatagagaat aacacgatgg ggtcttgggg atgtttcgag atagtaaacc
    27181 tctttgaaag gatattggaa ttgggcaaat tttgatttaa agtaaaagca atcttccgcc
    27241 agacttttac tatcttgact attggcatag aggagggctg tctcgatacg agattcaaac
    27301 tcctctgccg aaagggcctt atcaatgtag tccaaagctg acacttggta gcgaaaggac
    27361 agaggcataa actccgagtg agtcgtcaca aagacgatta gggcataagg gtcttgttcc
    27421 cgaatctttc tagccacttc cagtcccttc atctcttcat ttcgaatctc aatatccaaa
    27481 aagaatagct gatgggcccc cttctcatgc acctctgcca gcagttggtc cggcttgcca
    27541 aatacctcaa aagagctagg aatgatatga tgtgctttca aaagtttctc aatcgtcgtt
    27601 tcaattctag tctgttggga aaaatcatct tctaaaacaa atattctcat cttcttactc
    27661 tccctctttc aaccattttt gacgtatttc tctatagcga cgtctggcat acctgacagc
    27721 atattgacct tcttctccga gaaaaaggat tctttcttga aaatcaatcg attttaattt
    27781 atcaagatta accaaacaat ttcgatgaca tctcatcaaa gtttccccac attggttctc
    27841 aagattactt aaattttgaa gcatattaaa actagctttt tctgtaacaa tctgtacggt
    27901 atgggcttta gttggatgtg tttggatata gtagatatcg tcgatgttta ctttatagac
    27961 tgttttctgt gtctgaataa tcatatgttt cattggattc tcctcctaag aaaagaataa
    28021 cagaaaagat ctagcccaag cacacccaat cctaaacagt ctttgaaaac tcctaaaagg
    28081 attattttct acaacatcat gatgagctta caactatttt atcataaaat tcactcagcg
    28141 caattcaaga catttcaatg acaattaaag atttgaataa aaaaaagaat taaaagtgat
    28201 aaactaacag tatcaaaaca cagttgccag aagtaagact ggcacccaga ttaaaggagg
    28261 cattcccatg acagatacag accccatcaa aagagctcat actttgatta ctgacttaaa
    28321 caaagcctac caagcatgca aacaggcaag cgctgacgac gtccgctttc aggagcaatt
    28381 aaactctatt cttggttttc tagccaaggc tgaaacagtg gataatcgat tcttgattga
    28441 actagaaaaa ttttaccaga cttccagtct tctcatggga ctcagcgctc ttgatccaga
    28501 tgctccaact cgtgccgctt ggcgggccta tgaccgcttc cactttgacc aagtcaagac
    28561 caagttaata ctcaatgaaa atcaaagagc aaactaggaa gctagccgca agctgtactt
    28621 gagtacggta agacgacgct gacgtggttt gaagagattt tcgaagagta taagtctcta
    28681 cggaccaacc attatcctgt agtaacaaaa aagaagctga gacagactga actcaacttc
    28741 ttttttagtg tcgtatcagc aatgttagtc ctgcatctga cgttttacct gataaggcaa
    28801 atacaagact agtaaaacca aaccagctcc tagtaaggct agaagggcca gtttttcttg
    28861 gaaggtaatc aacccaacaa ctaattccac aagtaaaaca aaactggtca atcctcgaac
    28921 tacctcctgt aagccttttt ccttttgccc cttgtccagc ggaaagagtt gggtcaaata
    28981 ctggtagtca aaggcatgat agagggccag caactggaag agcaagaggt agttaaagag
    29041 aactaccact gctgtcgcaa tccaagcttg ctcgataaaa acctgcgcca gtacggaaag
    29101 taagagaaga cgaagactga gagcaaagag gtcgccattt cgcagataag aacgcagata
    29161 gagattttgc caaatcttcc caggcacctt ctgaacagcc tttaagataa agtccagata
    29221 ggcacgacgc ttaacgctgt ttgaaattcc cttgacctgc gtaaagaggg caaagaaacg
    29281 aagcaagact tgcttacgct tgctttcttg ggaaatgaca tagtcccagt ccagcccagt
    29341 ttcagtgaaa aatttgctgg ccttttgacg aaagtggaaa tattttccta cccccaataa
    29401 aagcacatag agcagaaaaa ctggcaagcc ataacccatt gctaaaaata aaggcgcaaa
    29461 taacagcaag aaaagggtct gtacaaagag ccaaaagact agggaaatgc cagtttgacg
    29521 cttgagatgg agcttgattt cctcttctcc aactaagaga aagagcttgt ctggagcctc
    29581 catataggtg gcaattcctc cccaaagtaa aagtaaaaca gacgtaattc ctacaaacaa
    29641 aaggataggc caatgatttt caggaaaatg ttgtaagagt tgactgtact ggtaggctag
    29701 aaagcccaac aggacaagca ggaacaagac aaagtggtca ttgagcacat agcgcagata
    29761 accaagacac tccttacgaa aggcctgctt tctctttaaa aacaagtctt tcatagatcc
    29821 tcctctttgg tcagagccaa gtaaatatca ttcaaactag cctcaggcat atcaaaggct
    29881 tcacgtagtt gcaggagatt gcctttggca cgcacctctc ccttgtgaag aatgacaaag
    29941 gcatcacaca tcttctccgc cgaatccagc acgtgggtac tcatgagaat agacttgccc
    30001 ttttgcttct ccacttccaa aagctgaatc aaatcagaaa tagccagcgg atcaagacca
    30061 aggaaaggct catccacgat gaaaagactt ggatccacca caaaagcaca gataatcatg
    30121 accttctgct tcatcccttt tgaaaaatga acagggaacc agtctaattt ctgttccaaa
    30181 cggaacattt ttaacaaggg ctctactcgt tcgaaagcca ctttttgctc aataccgtaa
    30241 gccatagcaa ccgtttcgat atgctctctg agggtcaatt cctcatacag actaggcgtc
    30301 tcaggaatgt agccaatctg cttgcggtag ctagtcgcat ctccttgcag agtcaggcca
    30361 ttgatattga tggagccact ataaggtgcc aacagaccga taatctcatt gatcgtcgtt
    30421 gatttcccag caccattgag accaatcaaa ccgaccaact gcccactttc aacagtaaag
    30481 gacacatctt tcaaaacagg aacatgaaca tagccacctg tcaggttttt aatttctaac
    30541 atattttctc caaatctggt ataatgtagc tatattatat caaaattcag tacagtagag
    30601 gtagatttta tgtcagattg cattttttgt aaaatcatcg caggggaaat tcctgcttca
    30661 aaagtatatg aagatgagca ggtccttgcc tttcttgata tctctcaagt aacactagga
    30721 cacaccttgg tcgtgccaaa agaacactat cgcaatcttt tggagatgga tgctacgagc
    30781 gccagccaac tctttgccca agtaccaaaa gtagctcaaa aagtcatgaa agtcactaag
    30841 gctgctggta tgaatatcat ttccaactgt gaagaagtcg ctggtcaaac agtttttcat
    30901 actcacgttc accttgtgcc tcgctacagt gctgacgatg acctcaagat tgattttatc
    30961 gcccacgaac cagactttga caaacttgct caagtcgctg aaaccatcaa aaacgcttaa
    31021 ggagttgcta tgaaattatc caacctactg ctatttgcag gagctgcagc cggaagttat
    31081 ctggttacaa aaaatcgcca aaccatcaca gatgaagtct tgaataccac tgaccgcgtt
    31141 caagctatca aggacgatgt ggatattatc caaaacagcc tgcaaatcat taaccagcaa
    31201 aaagaactta tcaaggaata ccaagaagac ttgacttaca agtttaaggt cttggaaaag
    31261 gatatccaga ctagactagc tgtgataaaa gaaatgcagg gaactgaaga taagtaaaaa
    31321 gagcccgacg gctctttttt aaaacgtaaa caagttatag tgaattgaat ttagaatagc
    31381 acatcatagt ttctaaagca ttgttagaga ttactttaaa atcctcttat caatttgttc
    31441 atattctatt tcaatctact atatatatcc catcaactat gcatcataat ttaggtaact
    31501 catactcaat aaaaatcaaa aagcaaacta gaaagctagg cacagactgc tcaaaacacc
    31561 gttttaaggt tgtggataga actgacgaag tcagctcaaa acactgtttt gaggttgtgg
    31621 atagaactga cgaagtcagt aaccataccc atgacaagcc gacgctgacg tggtttgaag
    31681 aaatttttga agagtatcat tcaccatttc acaactaaat cgaagacttt ctgccgtaat
    31741 gaaaacacct gaaacagctt ggtttcagct gtccggaaac tttaagactt aggttcaaag
    31801 tttaggtatg gaacttcgaa ggaggtcgct accgtccgtc attacttagg aaagtcttaa
    31861 aaaatctata aagtaaaaag agcccgacag ctctttttgt ttatactcaa tgaaaatcaa
    31921 aaagcaaact aggaaactag ccacgggctg ctcaaaacac tgttttgagg ttgtagatac
    31981 gactcacata tatacggcaa ggcaacgctg acgtggtttg aagagatttt cgaagagtat
    32041 tattctccat caaaggcatc ttttatatgg tcaaagaagc cttttttctt tggatttact
    32101 ttcaagtcac cagcagtcgc gaattctttc aaggctactt tttggcggtc gttcaagcct
    32161 gtcggtgtta cgacattaac agtaacgtat tggtcaccaa ctgcaccgcc acgaaggctc
    32221 ggtgccccct tactacgtag gcggaatttc ttaccagtct gagttccctc tggaataacc
    32281 aattcaacat caccgtaaac agttggaata tctactgtat caccaagagc cgcttggaca
    32341 aagttgaggt tgagattgta gaagatagtc gttccttcac gttcaaactt gtcgctagct
    32401 tctacagaaa ctactacata caagtcacca taaggtccac cgttaaagcc tgcttcacct
    32461 tgaccagcga ggcgaatttg ttgacctgtt tccacaccag cagggatttt cacatgtacg
    32521 ctatgagctt gtttctcatg acctgttcca tgacaggttg tacatggata tttgatttct
    32581 tttcctcgac cgtgacagac atcacaggtt acttggcgac gcatcatacc aagaggagtc
    32641 tgcgtatcga cgttaatgac accagcgcca tgacagcgtc cacaagtgac tggacttgtc
    32701 cctggcttag caccagagcc attacatgta cgacagccag cttcacgatg atacttaact
    32761 tccttctcag ttccgaagat agcttcttca aaggtcaaat tgacacgata ctggagatca
    32821 tctccttggc gaggagcgtt tggattgcgc gaagaaccgc ctccgccgaa gaaacttgag
    32881 aaaatgtcct caaaaccacc gaagccacct gccccattga aaccaccgaa accaccagct
    32941 ccaccaaaac caccattggc gcctgcagca ccatactggt cataggcagc acgtttttgg
    33001 tcgtcactca aagtctcata ggcttcttga acttccttgt acttgtcctc agcaccaggc
    33061 tccttgttga tatctgggtg atattttttg gaaagcttac gataagcctt tttgatttcg
    33121 tctgccgaag cgtttttgga tacccccaga cgatcataaa attcagtatt gttcatacaa
    33181 gataccaaga ccgtaaaatt cgactgaaaa ataggaaatc tgacgctgga gcgacgctcc
    33241 tagacagatt tctctttttt ccgagaattt aggtcgggtt caattccttt cttttatatt
    33301 gatgagataa tactccagcc actcggccct atcccttttt accgaaaaac agaggctggg
    33361 ttgcaacctc tgtggttaga ttattcattt gaaataaaaa tggttgtatt atctctagta
    33421 gtaatcttca aagacctttt agctaaatca aactcaaatt tattatagtg tgggtcttgt
    33481 gttttatata ggtgtaactc ctgacatata tgatccgaaa agtaaatcat aacatcttta
    33541 aacacagaag tgtggtcata tttactctta ccaacagcta cttctgtaaa ttctttataa
    33601 atgacatttc catttctttc cacagtcacc agcatttctg ttggattata atccaaatta
    33661 aataattatt caaaaaactt tatcttttca tgataatctg caatgtcaga aagattattt
    33721 ttattaacac tcataacact agccccttat ttttcagtaa actctccgtc tacgacgtca
    33781 tcgcctgcgt ttcctgttgc ttgtgcgcct tctgctcctt cttgagcttg ttgcgctgct
    33841 gcggcttgtt cgtagagttt cacagcaagg ccttgagctt tttcgttcaa cgcttcaagt
    33901 ttcgctttca tgtcgtccaa gttgttgtct tcttgagctt tcttaaggtc atcaagggca
    33961 gcttgggcag cgtcacgttc tgcgtcgaag cctttacctt cagtttcctt gattgtcttt
    34021 tcagtcgcaa agattgcttg gtctacttca ttacgaaggt ctacttcttc tttacgtttc
    34081 ttatcagctt cagcgtttgc ttcggcatct ttcatcatgc ggtcgatttc ttcgtcagtc
    34141 aaacctgagt tcgattggat gacaatagtt tgttcttttt gagttccaag gtctttggcc
    34201 ttaacagaca cgataccgtt cttgtctatg tcaaatgtta cttcgatttg aggaattcca
    34261 cgaggtgcag ctgggatatc agtcaattgg aagcgtccaa gagtcttgtt atctgctgcc
    34321 attgggcgtt caccttgaag aacgtggata tcaacggctg gttggttgtc tgctgctgtt
    34381 gagaagactt gtgatttaga tgttgggatt gtagtgttgc gatcgataag ttttgtaaat
    34441 actccaccca ttgtttcgat accaagtgac aatggcgtta catcaagaag gacaacgtcc
    34501 ttgacatcac cagtaatcac accaccttgg atagccgcac ccatagcaac tacttcatca
    34561 gggtttactg atttgtttgg ttctttacca gtttcagctt taacagcttc aacaacggca
    34621 gggatacgag ttgaaccacc aacaaggata acttcgtcga tttctgacaa gctcaaacct
    34681 gcatctgaaa gggcttgacg aactggaact tttgtacgtt caacaaggtc acgagtcaaa
    34741 tcatcaaatt tcgcacgagt caaagtcatt tccaagtgaa gaggtccagc ctcacctgca
    34801 gtgataaatg gcaagctgat ttgtgttgaa gttacaccag aaaggtcttt cttcgctttt
    34861 tcagccgcat ctttcaaacg ttgcattgcc atcttgtcag tagacaagtc gataccgttt
    34921 tctttcttga attctgctac caagtggtca atgatttttt ggtcaaagtc gtcaccacca
    34981 agtttgttgt cccctgcagt tgacaatacg tcgaagacac cgtcacccaa ttcaaggata
    35041 gagacgtcga atgtaccacc accaaggtca aataccaaga ttttttcttc tttgtcagtc
    35101 ttgtccaaac cataagcaag agctgctgca gttggttcgt taacaatacg ttctacttca
    35161 agaccagcaa ttttaccagc atcttttgtt gcttgacgtt gagcgtcgtt gaagtaagcc
    35221 ggaactgtga taacagcttt ggttactttc tcaccaaggt agtcttcagc gtagcctttc
    35281 aagtattgaa ggatcatagc tgagatttct tgtggagtgt attcttttcc atttgcagaa
    35341 actttttcag aagttcccat cttagatttg atagagataa ctgtatctgg gtttgtgact
    35401 gcttgacgtt ttgcagcatc accaacgatg atttctccgt ttttgaatga gactacagat
    35461 ggagttgtgc ggtttccttc tgggtttgcg atgattttgc tttcagttcc ttcaagaact
    35521 gcaactgctg agtttgttgt acctaagtca ataccgataa ttttagacat gtgtttttct
    35581 ccttgttagt taattttcta tttttctttt tgatactctt cttaagtggc gacgccgtca
    35641 gagcttgact tcgtcaatct ctttgactaa actttgagcc taaggtctca aaatttgcgc
    35701 aaatagcgcc acagcgaaga gtatcgtctt tggttcgctt cgctcactat tacaaagcca
    35761 aacatatttt atctttcttc atagtttatt gtcgtttcgg acaagttttc tattatgtaa
    35821 attgcgacac gaggagtcga aatcgatttt atttcgacga cgagttgctt tagctaccgt
    35881 cagaattgcc gaatcgaaca cgccctaagc tctgagtaaa aaagatagat tttcttgtgt
    35941 tcatcgaaca cttcgtcaat ctcctatttt tactgcgagc tttttacggg ctttgtatct
    36001 tagttataca ccactaccat tgctgggcgt aggatgcggt catggagttt gtagcctttt
    36061 tgaaagactt gggcgatggt atctactggg tgttcatcgt ctgctgggag agtttggatg
    36121 gccatatggt agttatggtc aaattcgcca tctgctgcga tttcttcaat tccttcttct
    36181 ttcaaagcgt gaatcaagct ttcttgcacc atccccaagc ccttcttcac atcatctgtc
    36241 aaaccttcaa ctgcaagtgc acgctcaagg ttgtcaagag atggtaagat tgcttttgcc
    36301 aagtcctggc tacgataacg ttgcaagttt tgacgttctt cgttggcacg gcgttggata
    36361 ttttgcattt ctgcatgagc gcgaagatat ttgttttcga actcatctgc acgttcattt
    36421 gccaagtcca acttagactt ttcaggagtt gtttcttcag ctgtttccac aacttcctct
    36481 tcttgaactt cttctacttc ttcatttttt atatcttggg ccatgttcgc ctcctttaat
    36541 gatttcaatc ttaatgtact tcgtaatgat tactgctgag gtagcggtaa aaatctgtca
    36601 acttcatagt caaaacacgg ttgaccacat tgacttgatt gattagctgt tggtaatcca
    36661 gattaactgg accgataatg gctagaattc caactcctcg ataaggaatg aggaacttac
    36721 tactaatcac cgctaggtca gctaaacagg actcttgacc gtctgcaaca cgaacatttt
    36781 gcatctgatc ctcacgcaac ccctcacgaa tctccaaggc caccttttgc ggttggtcaa
    36841 agaactgata ggcttctaga ttggcaaaat tcaagagatt gaccttgccc gccatcacaa
    36901 tgttttcgtt gaacatttcc ttaaagatgt gttcaaagag atcgatgaca ttatccgttg
    36961 ttgtaaagta acgctggata atctgcggaa tctccgtccg aatcttgtag tgaatatcta
    37021 aaacggtgtg accgaggaaa cgttcctgaa tgatgctctt cagtttcagc aaatcctcct
    37081 gcaagaagtt ccttggaatc agaaactgac tagtaaccgt tcgcgactcg tctagggtaa
    37141 ataccgccaa ggctgtatgt tgccccaaaa caacgatatc aaaggctgtc aaacgttgcc
    37201 tgctcggctc aacatccagt gccactaccg tacagccact caggtctgtt agcaagttag
    37261 cagcctcttg cagaatatcc tccaatttga agaattcctg atcaaaggct ttgacaatct
    37321 catatacctc attttcagcc agccggtgaa aatccagtga gtgtttcaca tagtactgaa
    37381 aaccagcaac acttggcatc cgaccgcttg aagtatgagc cttctcaagc aacccttgtt
    37441 tttctagttc cgccatgtca ttacgaatgg ttgcactgct agagttaata gactcttgca
    37501 aggcttttga tccgacaggt tcgtgcgttt tggtaaagat gtcaataatc agatttaaaa
    37561 tatcctgctg acgctctgta accatctcat cactcctctc tgtctgatca attagcactc
    37621 aatgcatcca agtgctaact tatgattcta ttatacaccc ttaaaagaga atgtcaagac
    37681 aaaaactcaa aaaattagca ctcttttatc aagagtgcta aaaatcaatc tgaagaccta
    37741 gaaccttgct attcatctac tcggtatttc ctttttagtc tgaaataacc atgaattaga
    37801 taagaaatca gaaaagcata taaaacaaaa ataagaaaga aagacataga aagatcctct
    37861 ctaaacaaac tcgtacaaac aacaagacca cctaagaaag tagttgtaca ggaacgaagt
    37921 ctagatcgca taacttccca tttgagcccc ttactcatat agacttgatc ctctggaagt
    37981 aaatcagaag acgatttacg aagaatcgaa caagaacctg ctcctatcaa ttcccaacct
    38041 ctatctctaa aatcttgcag ttcatgctta tattttttaa gaaatctaga atcatagata
    38101 cggtagatga catcgtctgg ttgacattgg tcaaaataga acaaaccaaa acgactcgtt
    38161 ctatacctcc aacctttcaa atgcatctca tgtaaatatt cttcttcctt gtccaaatca
    38221 acaatggtga aaatccgaaa ttctactctg ctattcattg tcttacccca aaattagaaa
    38281 acatgcctgg cgttatttat tagataattc tttccacttt tgactcaatc tccaaaaaat
    38341 ataagaaatc tgaatcgcaa aaactatcaa taaaacccaa tctattatga aaatcaaaaa
    38401 cactttccaa ctgaaagaac tacctccagt gacaaacttt gagaaaaacg gcagtagagc
    38461 taaaaagaga agtaaaatag gaagcatccg cattgttaaa atccgtttgg cataaaaaaa
    38521 tctttattta aacgaaaata ttatagcaaa atttacgcca g
//
LOCUS       DAVKBC010000015        37289 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVKBC010000015 DAVKBC010000000
VERSION     DAVKBC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37289
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.015"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            2..74
                     /locus_tag="VWX64_000904"
     tRNA            2..74
                     /locus_tag="VWX64_000904"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            99..171
                     /locus_tag="VWX64_000905"
     tRNA            99..171
                     /locus_tag="VWX64_000905"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:132..134,aa:Lys,seq:ttt)
     gene            177..258
                     /locus_tag="VWX64_000906"
     tRNA            177..258
                     /locus_tag="VWX64_000906"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Leu,seq:tag)
     gene            277..349
                     /locus_tag="VWX64_000907"
     tRNA            277..349
                     /locus_tag="VWX64_000907"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Thr,seq:tgt)
     gene            372..443
                     /locus_tag="VWX64_000908"
     tRNA            372..443
                     /locus_tag="VWX64_000908"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:404..406,aa:Gly,seq:gcc)
     gene            451..536
                     /locus_tag="VWX64_000909"
     tRNA            451..536
                     /locus_tag="VWX64_000909"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Leu,seq:taa)
     gene            546..619
                     /locus_tag="VWX64_000910"
     tRNA            546..619
                     /locus_tag="VWX64_000910"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Arg,seq:acg)
     gene            635..708
                     /locus_tag="VWX64_000911"
     tRNA            635..708
                     /locus_tag="VWX64_000911"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:669..671,aa:Pro,seq:tgg)
     gene            714..787
                     /locus_tag="VWX64_000912"
     tRNA            714..787
                     /locus_tag="VWX64_000912"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:748..750,aa:Met,seq:cat)
     gene            801..874
                     /locus_tag="VWX64_000913"
     tRNA            801..874
                     /locus_tag="VWX64_000913"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Ile,seq:cat)
     gene            885..974
                     /locus_tag="VWX64_000914"
     tRNA            885..974
                     /locus_tag="VWX64_000914"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Ser,seq:tga)
     gene            988..1061
                     /locus_tag="VWX64_000915"
     tRNA            988..1061
                     /locus_tag="VWX64_000915"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1022..1024,aa:Met,seq:cat)
     gene            1065..1137
                     /locus_tag="VWX64_000916"
     tRNA            1065..1137
                     /locus_tag="VWX64_000916"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1098..1100,aa:Phe,seq:gaa)
     gene            1157..1227
                     /locus_tag="VWX64_000917"
     tRNA            1157..1227
                     /locus_tag="VWX64_000917"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1189..1191,aa:Gly,seq:tcc)
     gene            1263..1336
                     /locus_tag="VWX64_000918"
     tRNA            1263..1336
                     /locus_tag="VWX64_000918"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Ile,seq:gat)
     gene            1343..1430
                     /locus_tag="VWX64_000919"
     tRNA            1343..1430
                     /locus_tag="VWX64_000919"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1377..1379,aa:Ser,seq:gct)
     gene            complement(1564..2001)
                     /locus_tag="VWX64_000920"
     CDS             complement(1564..2001)
                     /locus_tag="VWX64_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9190409.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(2208..3143)
                     /locus_tag="VWX64_000921"
     CDS             complement(2208..3143)
                     /locus_tag="VWX64_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU9190410.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(3140..4000)
                     /locus_tag="VWX64_000922"
     CDS             complement(3140..4000)
                     /locus_tag="VWX64_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9190411.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            4108..6270
                     /locus_tag="VWX64_000923"
     CDS             4108..6270
                     /locus_tag="VWX64_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU9190412.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIYKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            6305..7564
                     /locus_tag="VWX64_000924"
     CDS             6305..7564
                     /locus_tag="VWX64_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9190413.1"
                     /translation="MEWYKKIGLLATTGLALVGLGVCSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKEQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            7578..8444
                     /locus_tag="VWX64_000925"
     CDS             7578..8444
                     /locus_tag="VWX64_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9190414.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDSKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LGWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            8458..9291
                     /locus_tag="VWX64_000926"
     CDS             8458..9291
                     /locus_tag="VWX64_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9190415.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            9602..11044
                     /gene="gtfA"
                     /locus_tag="VWX64_000927"
                     /pseudo
     CDS             9602..11044
                     /gene="gtfA"
                     /locus_tag="VWX64_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
     gene            11182..12375
                     /locus_tag="VWX64_000928"
     CDS             11182..12375
                     /locus_tag="VWX64_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU9190416.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            13063..15042
                     /locus_tag="VWX64_000929"
     CDS             13063..15042
                     /locus_tag="VWX64_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9190417.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTNSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            15109..16605
                     /locus_tag="VWX64_000930"
     CDS             15109..16605
                     /locus_tag="VWX64_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190418.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            16605..17531
                     /locus_tag="VWX64_000931"
     CDS             16605..17531
                     /locus_tag="VWX64_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190419.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVVKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            17540..18607
                     /locus_tag="VWX64_000932"
     CDS             17540..18607
                     /locus_tag="VWX64_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190420.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            18618..19544
                     /locus_tag="VWX64_000933"
     CDS             18618..19544
                     /locus_tag="VWX64_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190421.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(19619..20945)
                     /locus_tag="VWX64_000934"
                     /pseudo
     CDS             complement(19619..20945)
                     /locus_tag="VWX64_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21100..21810)
                     /gene="treR"
                     /locus_tag="VWX64_000935"
     CDS             complement(21100..21810)
                     /gene="treR"
                     /locus_tag="VWX64_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU9190422.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21995..23962
                     /gene="treP"
                     /locus_tag="VWX64_000936"
     CDS             21995..23962
                     /gene="treP"
                     /locus_tag="VWX64_000936"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU9190423.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24140..25765
                     /gene="treC"
                     /locus_tag="VWX64_000937"
     CDS             24140..25765
                     /gene="treC"
                     /locus_tag="VWX64_000937"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU9190424.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            26021..26269
                     /locus_tag="VWX64_000938"
     CDS             26021..26269
                     /locus_tag="VWX64_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU9190425.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26476..27270
                     /gene="racE"
                     /locus_tag="VWX64_000939"
     CDS             26476..27270
                     /gene="racE"
                     /locus_tag="VWX64_000939"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU9190426.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27267..28238
                     /locus_tag="VWX64_000940"
     CDS             27267..28238
                     /locus_tag="VWX64_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU9190427.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28214..28735
                     /locus_tag="VWX64_000941"
     CDS             28214..28735
                     /locus_tag="VWX64_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU9190428.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28732..29193
                     /locus_tag="VWX64_000942"
     CDS             28732..29193
                     /locus_tag="VWX64_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9190429.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29184..29924
                     /gene="xerD"
                     /locus_tag="VWX64_000943"
     CDS             29184..29924
                     /gene="xerD"
                     /locus_tag="VWX64_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU9190430.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29924..30652
                     /locus_tag="VWX64_000944"
     CDS             29924..30652
                     /locus_tag="VWX64_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU9190431.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPIELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30671..31240
                     /locus_tag="VWX64_000945"
     CDS             30671..31240
                     /locus_tag="VWX64_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU9190432.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31227..31949
                     /locus_tag="VWX64_000946"
     CDS             31227..31949
                     /locus_tag="VWX64_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9190433.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31949..32191
                     /gene="yidD"
                     /locus_tag="VWX64_000947"
     CDS             31949..32191
                     /gene="yidD"
                     /locus_tag="VWX64_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU9190434.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(32416..33381)
                     /locus_tag="VWX64_000948"
     CDS             complement(32416..33381)
                     /locus_tag="VWX64_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9190435.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGVADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33477..34229)
                     /locus_tag="VWX64_000949"
     CDS             complement(33477..34229)
                     /locus_tag="VWX64_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9190436.1"
                     /translation="MKLENIDKSIQKQDILQGISLKVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(34226..35182)
                     /locus_tag="VWX64_000950"
     CDS             complement(34226..35182)
                     /locus_tag="VWX64_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU9190437.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(35172..36131)
                     /locus_tag="VWX64_000951"
     CDS             complement(35172..36131)
                     /locus_tag="VWX64_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190438.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36554..37255)
                     /gene="galE"
                     /locus_tag="VWX64_000952"
     CDS             complement(36554..37255)
                     /gene="galE"
                     /locus_tag="VWX64_000952"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9190439.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKVYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
BASE COUNT        10656 a         7033 c         8257 g        11343 t
ORIGIN      
        1 aggtcccgta gtgtagcggt tatcacgtcg ccctgtcacg gcgaagatcg cgggttcgat
       61 tcccgtcggg accgtttaag gtaacgcaag ttattttaga ctcgttagct cagttggtag
      121 agcaattgac ttttaatcaa tgggtcactg gttcgagccc agtacgggtc atatatgcgg
      181 gtttggcgga attggcagac gcaccagatt taggatctgg cgcttaacgg cgtgggggtt
      241 caagtccctt aacccgcatt aagatataac aaatgagccg gcttagctca gttggtagag
      301 catctgattt gtaatcagag ggtcgcgtgt tcaagtcatg tagccggcat ttttagatag
      361 aagaaaacag tgcgaacgta gttcagtggt agaacaccac cttgccaagg tgggggtcgc
      421 gggttcgaat cccgtcgttc gcttagagag gccggggtgg cggaactggc agacgcacag
      481 gacttaaaat cctgcgattg gtaacgatcg taccggttcg attccggtcc tcggcataat
      541 atggagcacc cttagctcaa ctggatagag tacctgacta cgaatcaggc ggttagaggt
      601 tcgactcctc tagggtgcat ttttctattt aactcgggaa gtagctcagc ttggtagagt
      661 acttggtttg ggaccaaggt gtcgcaggtt cgaatcctgt cttcccgatt catggcggtg
      721 tagctcagct ggctagagcg tccggttcat acccgggagg tcgggggttc gatccccttc
      781 gccgctataa tgatcttgtc ggacctttag ctcagctggt tagagctctc ggctcataac
      841 cgagtggtcg taggttcaag tcctacaagg tccatttgaa tattggagga ttacccaagt
      901 ccggctgaag ggaacggtct tgaaaaccgt caggcgtgta aaaacgtgcg tgggttcgaa
      961 tcccacatcc tccttttata ttattaacgc gggatggagc agctcggtag ctcgtcgggc
     1021 tcataacccg aaggtcgtag gttcaaatcc tgctcccgca ataaggctcg gtagctcagt
     1081 tggtagagca atggattgaa gctccatgtg tcggcggttc gattccgtct cgcgccattt
     1141 tattgatagt atttatgcgg gtgtagttta gtggtaaaac tacagccttc caagctgttg
     1201 tcgcgagttc gattctcgtc acccgctttg aactttgttc aaattaccaa gttttttaac
     1261 ttgggcgcgt agctcaggtg gttagagcgc acgcctgata agcgtgaggt cggtggttcg
     1321 agtccactcg tgcccattaa ttggagaatt actcaagagg ctgaagagga cggtttgcta
     1381 aatcgttagg tcgggtaact ggcgcaaggg ttcgaatccc ttattctccg ttttaatgag
     1441 agtttgtaac tctctttttt atttttagag acaataaagc ttcagatccg taaaacttaa
     1501 ttgaattact aatctgaagt tatttttatg gctctttgtc aactgtagtg ggttgaagaa
     1561 aagctaagct cgagaaagga caaatttcgt cctttctttt ttgatgttca aagcgataaa
     1621 aatccgtttt ttaaagtttt caaagtttcg aaaaccaaag gcattgcact tgataagttt
     1681 gatgagatta ttggtcgctt ccagtttggc gttagaatag tgtagttgaa gggcgttgac
     1741 aatcttttct ttatctttga ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg
     1801 cttaagattg tcctcaataa gtccgaaaaa tttctctggt tcctttttct tcattagact
     1861 tccacaatca gggcaagatg gagcctcata atccagctta gcgataattt ctttgtgggt
     1921 atccatattg atgatatcta gaatcttgat gtttgggtct ttaatatcga gcagttttgt
     1981 gataaaatgt aattgttcca tatgaatctt tctaatgatg gttttgtcgc ttttcattat
     2041 aggtcatatg ggactttttt tctacaacaa aataggctcc ataatatcta taagggattt
     2101 acccactaca aatattatag agccaataaa acttcagatc cgtaaaactt aattgaatta
     2161 ctaatctgaa gttattttta tatcgtttat attataattg tgttatttta cttccaacta
     2221 ttgagagaaa tttcgccact atttagccag atttcttttc cgttatcaca ttgaactaaa
     2281 agttttccat tttctgagat gtctttagca agtcccttgt agtctttttg ctctagtgtg
     2341 aaagtgactt cttttcctag aatgaatgac tgttttttgt ataggtataa tagctcttct
     2401 gctggtgttt cgaagaaagc acgccagatt tctatgatca attcattcct tgttatagga
     2461 gctgtagctt taaataagct ggcagctttt tcttttaatt cctgagggaa gtctttaata
     2521 gtgaaattga tacctactcc aataatgata tctgtgacta agccagtttc tacagaggtc
     2581 attgcttcag taaggattcc tccaatttta tgattgttta gatagatatc attgacccat
     2641 tttatgtcga catctattaa agttaggttc ttaatggctt tgtagacagc tccagctaca
     2701 agtagtgtgt aggatggtaa tttgtcatag gggagatttg gtttaagatg gagtgtcata
     2761 taaataccac cttgtggtga gtagaaggaa cgttgaaaac ggcctcggcc tgctgtttga
     2821 taggaagcta gatagagggt atttgcttca tggcctaaat caattgcttc ttttgcatct
     2881 agttgtgttg attttgtttc gggtttaaag ctgactttaa ttggaagatt ttcttctaga
     2941 atctctggaa gaataaggtc accattcatc agtttgtatc ctctattttt gatactatca
     3001 atttcaatgc cttcttgttc tagtcgcttg atagctttcc aaattgatgt tcggcttagg
     3061 gatagttttt ctgcgatttt ttctccgctg atatagtcgg tttctttaga taggatttgg
     3121 tagacagctt ggtaggattt cataatgttg cctttctcac tagttggtat tgagagtatt
     3181 cttttcttgt atgacttgga gtctgattaa agtattgttt ataagctttc gaaaaatgga
     3241 gtggatctga aaaacctacc gagtatgcaa ttaccttgat ggactcttgg gtattttcga
     3301 gaagttgtct agctcggtgc attcgaacgt agagtaggta ttctttgggt gataaggtat
     3361 taaattcttt gaatacgctt gataagtagc ttctgtgaac ggatagttct tttgctaaat
     3421 cttgaattgt aagtgattga ggatagtggc tatcaattaa tcgtttgcat tcaagataga
     3481 gttggtgggt tgatgaaata ttcttttttt tctgattggg agcaatagtt cccagatgaa
     3541 acatcagttc atgaagttgt cccatgatat ggagttgagc taattcactt gattttgtaa
     3601 tctgagcgaa gcggacaatg tctgagatga gttttgcagt agtctgggta tgacaagttt
     3661 cagattggat gagataggat tgatcagaaa tttgagaaag agcaaaataa tcaggggatt
     3721 tccctccagt gattcctaac cagtagtagg cccaaggttc tttactatct gcttgataaa
     3781 aggttagttc ctctggtttt aatagaaaga aatctccttc ttttaaatca acaattttac
     3841 ccttgtaatg aaattttcct tgtcctttag taatgtaatg taggacgtat gtatcacgaa
     3901 tggctggacc aaaagagtaa ttaggtgtgc attcctcata tccataaaag cttagggcaa
     3961 ggtcgattgt tccagtctgg tattctgaaa aaactaacat gtgctacctc ctacctaaca
     4021 ttttaccata ttcttgagac atttttctat tttagaaagc gatttcaggt gataaaatat
     4081 aatcaataaa gtgatgaggt gaagtaaatg ggagttagga tagagaataa tctattttat
     4141 gttgagagta aaaatctaag tttgattatt gaaaatcgaa atggctactt acttttgaaa
     4201 catttaggaa agactattaa gaactataaa ggttccaata gtgtttatga acgagaccat
     4261 gccttttcag gaaatccaac agctactaat cgaaccttta gtttagatac tcaacgtcaa
     4321 atttttggac aacatggctt aggagatttt aggaaaccaa ccatacaggt tcagcataat
     4381 gtaactgaag taacagactt tcgatttgta gaagcaaaga ttttaaaagg tcagaatggt
     4441 ccacagggct taccttctcc acatagcatg gacgatacag agactcttgt cttaatgtta
     4501 gaagattcta aggctcaact tagtctgact ttgtattata ctacttttaa taatgatgcg
     4561 actattgcta gctacagtaa attagataat aatagtaatc aggaagttgt catctataaa
     4621 gatttttctt ttatggctga ttttccagct gcagattacg aaatagtaac tctgcagggt
     4681 gcttatgctc gtgaaaagac tgttagacgt caacaggtag aacaaggaat cttttcgatt
     4741 agttcaaacc gaggtgcttc tggtcatgct caaacaccag ctcttctact atgcgaacaa
     4801 ggagtcacag aggatgctgg gaatgtgttt gctattcaac taatgtatag tggcaacttt
     4861 gaagcttttg ttcaaaaaaa tcaattgaat gaagttcggg tggctattgg cattaatcca
     4921 gaaaactttt cttggaagtt agcccctgag gaatactttg aaacaccggt agctttagtg
     4981 actcattcag atcagggatt aactggtatt agtcatgaaa gtcagaattt tgtactgaag
     5041 cacattatgc taagtgaatt ttctaaaaaa gaacgtccaa ttctaatcaa taactgggaa
     5101 gctacttact ttgactttca gagagaaaaa ctgttagagt tagcagatga agctaagaaa
     5161 gttggcattg aactttttgt attagatgat ggttggtttg gcaatcgttt tgatgataat
     5221 cgtgctttag gtgattgggt tgttaatgag gaaaaactgg gtggaagtct agaaagtctg
     5281 atttcagcta tccatgaaag aggtttgcag tttggacttt ggttagaacc cgaaatgatt
     5341 tctgtagata gtgatttgta tcgtcaacat cctgactggg ctattcaggt tcctggctat
     5401 gagcatactt attctcggaa tcaattagta cttaatcttg ccaatcctca ggtagtagaa
     5461 tacttgaaaa gtgtcttaga tcaactccta tcttatcatg atattgatta cattaaatgg
     5521 gatatgaacc gcaatatcac taagctaggg aatggattaa cttatctaga gacacagatg
     5581 caatctcatc agtacatgct ggggctttac gaactcgttt cttatctgac agagaagcac
     5641 agccatattc tctttgagtc ctgctctggt ggtggtggac gaaatgatct tggtatgatg
     5701 cgctatttcc cacaagtctg ggctagtgat aatactgatg ccattgcacg tttaccaatt
     5761 caatacggtt catcctatct ctatccaacc atttctatgg gggctcatgt gtcagcagta
     5821 ccgaatcatc agatgggacg aatgacacca ttagaaacac gtggccttgt agcaatgatg
     5881 ggaaatttgg gctatgaact tgatttgaca aatttatcag atgaagagaa agctacgatt
     5941 gctaatcagg tgaacttgta taaagaatta cgaccagtag ttcagttagg acagcagtat
     6001 agactaatta atcctgatac tgtatccaat gaagcagctg tacaatttaa ttacggaaat
     6061 caaacgattg taacctacgt tcgcgtttta tctgttgtag agaccatgga aacaacttta
     6121 aaattaaaag atttggatga agagggacta tataaattac aggaaaatgg cgaagtttac
     6181 tcaggtgcag aactaatgta tgcgggccta actgttatct tatcccaagg agattttttg
     6241 agtagacagt atatttttag aagactatga taagggtgta taaatttata aaggaggctt
     6301 tctaatggaa tggtataaaa aaatcggact tcttgcaact acaggtttag ctttggttgg
     6361 gcttggcgtt tgctccaact atggtaaatc tgcggatggc acagtgacca tcgagtattt
     6421 caaccagaaa aaagaaatga ccaaaacctt ggaagaaatc actcgtgatt ttgagaagga
     6481 aaaccctaag atcaaggtca aagtcgtcaa tgtaccaaat gctggtgaag tattgaagac
     6541 acgcgttctc gcaggagatg tgcctgatgt ggtcaatatt tacccacagt ccatcgaact
     6601 gcaagaatgg gcaaaagcag gtgtctttga agatttgagc aacaaagact acctgaaacg
     6661 cgtgaaaaat ggctacgctg aaaaatatgc tgtaaacgaa aaagtttaca acgttccttt
     6721 tacagctaat gcttatggaa tttactacaa caaagataaa ttcgaagaac tgggcttgaa
     6781 ggttcctgaa acctgggatg aatttgaaca gttagtcaaa gatatcgttg ctaaagaaca
     6841 aacaccattt ggaattgcag gtgcagatgc ttggacactc aatggttaca atcaattagc
     6901 ctttgcgaca gcaacaggtg gaggaaaaga agcaaatcaa taccttcgtt attctcaacc
     6961 aaatgccatt aaattgtcgg atccgattat gaaagatgat atcaaggtca tggacatcct
     7021 tcgcatcaat ggctctaagc aaaagaactg ggaaggtgct ggctataccg atgttatcgg
     7081 agccttcgca cgtggggatg tcctcatgac accaaatggg tcttgggcga tcacagcgat
     7141 taatgaacaa aaaccgaact ttaagattgg gaccttcatg attccaggaa aagaaaaagg
     7201 acaaagctta accgttggtg cgggagactt ggcatggtct atctcagcca ccaccaaaca
     7261 tccaaaagaa gccaatgcct ttgtggaata tatgacccgt ccagaagtca tgcaaaaata
     7321 ctacgatgtg gacggatctc caacagcgat cgaaggggtc aaacaagcag gagaagattc
     7381 accgcttgct ggtatgaccg aatatgcctt tacggatcgt cacttggtct ggttgcaaca
     7441 atactggacc agtgaagcag acttccatac cttgaccatg aactatgtct tgaccggtga
     7501 taaacaaggc atggtcaatg atttaaatgc cttctttaac ccgatgaaag cggatgtgga
     7561 ttaggagtag agagactatg aaaaaagtat tacaaaaata ttgggcatgg gcttttgtgg
     7621 tcatccccct cttgttacaa gcaattttct tctatgtgcc gatgtttcaa ggagcctttt
     7681 acagttttac caactggaca ggattgactt ataactacaa atttgtcggc ttaaacaact
     7741 ttaagctcct cttcatggat tcaaaattca tgaatgcgat tggctttacc gcaatcatta
     7801 cgattgccat ggtggttggt gagattgcac tcgggatctt cattgcgcgt gtcttgaact
     7861 ctaaaatcaa aggccaaacc ttcttccgtg cttggttctt cttcccagct gttttatctg
     7921 gtttgacagt ggctttgatc ttcaagcaag tcttcaacta cggtcttcca gcgattggga
     7981 atgcccttca tattgaattt ctccaaacca gtcttttagg gactaagtgg ggagcaatct
     8041 ttgcggctgc ctttgtcctt ggttggcaag gggtggctat gcccatcatc atcttcctag
     8101 ctggtttgca atctattcca actgagatta cagaggcagc aaggattgat ggtgcgacta
     8161 gcaagcaagt tttctggaac attgaattgc cttacttgct accaagtgtc tctatggtct
     8221 ttatcctagc cctaaaaggt gggctgactg cctttgacca agtctttgcc atgaccggtg
     8281 gtggtccaaa caatgccaca acctcacttg ggctcttggt ttataactat gcctttaaaa
     8341 acaaccaatt cggttatgcc aatgccattg ccgtaatctt gttcctctta attgtagtga
     8401 tttcgatcat ccaattgaga gtatctaaga aatttgaaat ttaagaggag aagcatgatg
     8461 aaacaagatg aaagaaaagc cctgattggc aaatacattc tattgattct aggatcggtt
     8521 ctgattttag tgccgctcct tgctaccctc tttagttcct ttaaacccac taaggatatt
     8581 gtagataatt tctttggctt tccaaccaac ttcacatggg acaactttag ccgtctctta
     8641 gctgatggga ttggaggcta ttattggaac tctgtcgtca tcactgtctt gtctttactt
     8701 gcagtaatga tctttatccc tatggcagcc tactccatcg ctcgcaatat gagtaaaaga
     8761 aaagccttta ccatcatgta taccctctta atcctcggaa tcttcgtacc tttccaagtc
     8821 atcatgattc cgattacggt tatgatgagt aaactcggtt tggctaatac ctttggtttg
     8881 atcttgctct acttgaccta tgcgattcca cagaccctct ttctctatgt tggctatatc
     8941 aaaatctcga ttccagaaag tctggatgaa gcagcagaga tcgatggggc taatcaattt
     9001 acaacctatt tccgcatcat cttcccaatg atgaaaccga tgcatgcgac aaccatgatc
     9061 atcaatgccc tttggttctg gaatgacttc atgttgccac tccttgtctt gaaccgggat
     9121 tccaaaatgt ggactctgcc tttgttccaa tacaactacg caggccaata tttcaacgac
     9181 tacggaccaa gctttgcctc ttacgtggtc ggcattatca gtatcaccat tgtctatctc
     9241 ttcttccaac gccatatcat ttcaggaatg agcaacgggg cagtgaagta atactcaatg
     9301 aaaatcaaag agcaaactag gaagctagcc gcaggctgta cttgagtacg gtaaggcgac
     9361 gctgacgtgg tttgaagaga ttttcgaaga gtataagaag agctcatgga atctatagtc
     9421 tttgacacag aggaagagtt cagcttgttg ataattctat gtagaaaaca agaaagtagt
     9481 actttgttta tcacagtcta tattagtacg agtttgatga taaatagaga tttaaaatga
     9541 atttgattta cgaagccaga tcatatgaga cttggcttca attagaaaaa ggagagtaat
     9601 gatgccaatt caaaataaaa ccatgttgat tacctattct gatagccttg gaaataatct
     9661 taaagactta tatgataatt tggaagagca ttttggagat gctattggag gagttcacct
     9721 tttaccattt ttcccatcaa caggtgatcg tggatttgcg ccagttgact acgacgaagt
     9781 ggactcagct tttggtgatt gggaggatgt taagcgttta ggtgagaaat attatcttat
     9841 gtttgatttt atgattaatc atatttctcg tcaatccaag tattataagg actatcaaga
     9901 aaaacatgaa gccagtgaat ttaaagatct ctttttaaac tgggataagt tttagccaga
     9961 aaaccgtccg acacagtctg atgtagattt aatttacaag cgtaaggatc gtgcaccaaa
    10021 gcaagagatt gtgtttgaag atggttcagt ggaacatttg tggaatacct ttggtgagga
    10081 gcagattgat cttgatgtga ccaaagaagt aactatggaa tttatccgta agaccattca
    10141 gcacttggca agtaatgggt gtgatttgat tcgtctagat gcctttgctt atgcagtgaa
    10201 gaaattggat actaatgatt tctttgtgga accagatatt tgggatttat tggacaaagt
    10261 tcgagatatc gctgctgagt atgggacaga gcttttacct gagattcatg aacactattc
    10321 gattcagttt aaaatagcag accatgatta ctatgtttat gattttgctc ttccaatggt
    10381 gacactttat actctttaca gttccagaac agagcgtttg gctaagtggt taaagatgag
    10441 cccgatgaag caatttacga cgctagatac ccatgatggg attggagtag tagatgtcaa
    10501 ggatatcctg accgatgagg agattgacta tgcttcaaat gaactctata aggttggagc
    10561 caatgtcaaa cgtaagtact ctagtgccga gtataacaac ttagatatct accaaatcaa
    10621 ttcaacctac tattcagcgc ttggagatga tgatgtcaag tattttctcg ctcgtctaat
    10681 tcaagctttt gccccaggta ttcctcaggt ttactatgtg ggtctattag caggcaagaa
    10741 tgacttgaaa ttattagaag aaactaaaga aggtcgaaat attaatcgtc attactatag
    10801 caacgaggaa atagcaaaag aagtgcaacg acctgttgtg aaggcccttc tcaatctatt
    10861 ttctttccgt aaccgttcag aagcctttga tctagaaggg actactgaga tagagacacc
    10921 aacagctcac agcattgtaa tcaaacgtca aaataaagat aagtccgtaa cagcagtagc
    10981 agaaattgat ttgcaaaatc agacttatcg ggtaattgag aatggagttg aagtaacatt
    11041 ttgaagcctt gatatggtgg ataaaatagg gtttttattt tggaaaacgt ttcctttgtt
    11101 ttcaaattgc taaaaaagtg gtacaatata ggatagctta ctattatctg aatcagctga
    11161 tttggagaga aaggattcat tttgaaatca ataggcttta ttgaaaagct gaaggggttg
    11221 tctagtaaag agctgatttt attgggaatt atcctaagta tctttttacc cttttatctt
    11281 tttgtagttg tactctgttt atatattatc agtttgattt ttacaggaga catgaaaagt
    11341 attcttcaga aaatggggga gcatccgatg ctgcttcttt ttcttagcta tagtactgtt
    11401 atatccattc ttgcacaaaa ttggatgggt cttgtggctt cagtaggaat gtttctattt
    11461 actattttct ttttgcacta tcagtcgatt ttatcccata aattctttcg attgattttg
    11521 cagttcgtct tgtttggtag tgtcttgtca gctgcttttg ccagtttaga acatttccaa
    11581 attgtgaaga aatttaacta tgcttttctt tcacccaata tgcaggtgtg gcatcagaac
    11641 cgggcagaag tgaccttctt taatcctaat tattatggaa ttatttgttg tttctgtatt
    11701 atgattgctt tctatctgtt tacaacgacc aagttgaatt ggttgaaagt attctgtgtg
    11761 attgcaggct ttgttaatct ctttggtttg aactttactc aaaatcgaac tgcctttcct
    11821 gctattatcg ctggagcaat tatctatctc tttacgacta ttaaaaactg gaaggccttt
    11881 tggcttagta ttggggtctt cgcgattggt ttgagtttcc tcttttctag tgatttggga
    11941 gttcgaatgg gtactttaga ctcttctatg gaagaacgca tttctatctg ggatgctggg
    12001 atggccttgt ttaagcaaaa tcctttttgg ggtgaagggc cattgaccta tatgcactct
    12061 tatcctcgga tacatgctcc ttatcatgaa catgcccaca gtctttatat tgatacgatt
    12121 ctgagttacg gaattgtggg taccatttta ttagttttgt cttctgttgc tcctgttcgc
    12181 ttgatgatgg atatgagtca ggagtcgggg aaacgtccga ttatcggcct ttatctatct
    12241 ttccttacag tggttgctgt gcacggaatt tttgacttgg ctctcttctg gattcagtca
    12301 ggctttattt tcttgctagt tatgtgcagt attccattgg agcatcgaat gttggtatcg
    12361 gacatgacgg attaagtttt ataagtttga aatcttctac cttgggtagg agattttttt
    12421 atacgatggg catgtcgtgc atctgaggtg taagtcctct gtagggatcc actaccggtg
    12481 aatacaatag cgctccccaa gcctgactat cgtgaggtag cggattaaaa tggtctgggg
    12541 atagatcgtt ttaagtctga cgcaggaaat aagaattgtc agagaaagca atagtgaaat
    12601 cgtaggctat gaatagaaac gtgatagcga ggagcatata gtggataagg tagcgagaaa
    12661 ttttaaagta taaaagatag tcttaatcta tatatgtaaa tcacaaaagt aattgaattc
    12721 ggaataaggt tggtgtgaaa agacatagta aactgaatct tgaatactag aatgatactt
    12781 ctacaatatt gttataattt aatttgaatt ccaaaatcac attgttccgt ccgtatttca
    12841 ttttactgta tgtcttccta aactccaaag tttctgcgtc aaatttccta ttttcactgt
    12901 agtctttgac acttcgaacg acaatttgaa tcatatattc aaaaaaaaaa tgaaaaattt
    12961 gtgccaacaa gcctaaatat tctgaaaatt tgtttgattt ttaatggata atgtgatata
    13021 atggttgtca atctataatt cacataaaca gaggagtaga aaatgaaaaa aaatcgtgta
    13081 tttgctacag caggtcttgt tttattagca gcaggtgtac ttgcagcatg cagttcttca
    13141 aaatcatctg attcatcagc ccctaaagct tatggctatg tttatacagc agacccagaa
    13201 accttggact acctgatttc aagtaaaaat agtacaacag tagtgacttc aaatgggatt
    13261 gatggtttat tcactaacga taattacggt aatcttgctc ctgcagttgc agaggattgg
    13321 gaagtctcta aggatggttt gacctacact tataagattc gtaaaggggt taaatggttt
    13381 acctctgatg gagaagaata tgcagaggtg acggctaaag atttcgtgaa cggtttaaaa
    13441 cacgcagcag ataaaaaatc agaagctatg tatttagctg aaaattcggt taaaggcttg
    13501 gcagattatc tatcaggaac ttcaacagat ttttcaacag ttggtgtcaa ggcggttgat
    13561 gattatacgt tacaatacac tttgaaccag cctgaaccgt tctggaactc taagttgacc
    13621 tattctattt tctggcctct gaatgaagaa ttcgaaacat caaaaggaag cgattttgct
    13681 aaaccaacag atccgacatc cttgctttat aatggtccat tcttgttgaa agggttgact
    13741 gcaaaatctt ctgtagagtt tgtaaaaaat gagcaatatt gggataaaga aaatgtccac
    13801 ctagatacta tcaatctagc ttactatgat ggatcagatc aggagtcgct agagcgtaac
    13861 ttcactagtg gagcttatag ttatgcccgt ctttacccta ccagctccaa ctattctaag
    13921 gttgcagaag aatacaagga caatatctat tacacacaat caggctctgg gattgctggt
    13981 ctgggtgtga atattgatcg ccaaagttac aactatactt ctaaaactac agattcagag
    14041 aaagtagcta ctaagaaggc attgcttaac aaagatttcc gtcaagcctt gaattttgct
    14101 cttgatcgct cagcttactc agctcaaatc aatggtaaag atggagcagc tttagcagtt
    14161 cgtaatttat ttgtaaaacc agactttgtt tcagctggtg agaagacctt tggtgattta
    14221 gtcgctgctc aacttcctgc ttatggtgat gagtggaaag gtgtgaattt agctgatggg
    14281 caggatggtt tattcaatgc tgacaaggcc aaggcagagt ttgcgaaagc taagaaagct
    14341 ttagaagcag acggcgttca gtttcctatt catctggacg ttccagtaga ccaagcatca
    14401 aaaaactaca tatctcgtat tcagtctttt aaacaatctg tagaaacagt tcttggtgtt
    14461 gaaaatgtcg ttgttgatat tcaacaaatg acaagtgatg aattccttaa tattacttac
    14521 tatgctgcca atgcttcatc tgaggattgg gatgtatcag gaggagtttc atggggtcca
    14581 gactatcaag acccatctac ttacctggat attttaaaaa caaatagcag tgaaactaca
    14641 aaaacatatt taggatttga taatccaaat agcccttcag tagttcaagt tggtttgaaa
    14701 gaatacgata aattagttga tgaagctgcc agagagacaa gcgacttgaa tgtccgttat
    14761 gaaaaatatg cagcggctca agcatggttg acagatagtt cactctttat tcctgctatg
    14821 gcttcttctg gtgcagcacc agtgctttca cgaattgttc catttactgg agcttctgcg
    14881 caaacaggct ctaaggggtc agatgtttac ttcaaatatt tgaaattaca agataaagtg
    14941 gtgactaagg aagagtatga aaaagctcgt gaaaaatggt tgaaagaaaa agctgaatca
    15001 aatgagaaag ctcaaaaaga attggcaagt catgtgaagt aaataatttc taatagaact
    15061 ttctctccat gaggagaagg ttcttttggg atttttaaag gaaataatat gaaaaaatat
    15121 atttttatgc gtgttttgcg gtcattggtt tcgattttct tagtaacgac tttgacctac
    15181 acgattatct ataccttggt tcctcgaaaa ttgattttca agcaggatcc taactataat
    15241 aaaattgcga caacggctga taaacgtgat aactatgaaa atactgtgtt tgagcgtatg
    15301 ggctacattg agtattacga tactaaagag ttgcaagaaa aggcaagtag catggattct
    15361 tctgtaacag tagaagcaaa tgcgaccaat aaagctattt atgaaaagta catcaatcaa
    15421 ttaggtcatg gttggacttt gggagaattt actgaaagtg gtcaattcta tgctactcgt
    15481 gaaattccaa tttttgaacg tgtttttcac ttctatgcta acttgattga cattgaccat
    15541 acaaataaaa tccaagaccc tgaaaatcca gacttgaaac gctaccttcg ttttgaaaat
    15601 gatccagcta tcggatggtc attggtcggt tcaggaacta aacataaata tctcttgtac
    15661 tttaacagtc agttcccatt tgttcatcaa aactttgtga acttgaattt aggtgactct
    15721 tacccaacct atgctaatac accagttctt caggttatta ctcaaggtca aggacaaacc
    15781 aaaactgccc aagttcagtt cccaacaggt aagaaaacgt cttctgtaaa tatttactca
    15841 agaacctaca agtcacctag tcaggctgac tctcgtgaag tagctagcta tgggaaagat
    15901 gatccttata cagcgactga aagtaattac caatatccat ctatgattgt cagctctgct
    15961 attactggtt tgattggttt ggttcttgcc tatgctcttg ccgtgccact tggttcagcc
    16021 atggctcgtt tcaagaacac ttggattgat agcctctcaa cagggacttt gaccttcttg
    16081 cttgctcttc caacgattgc cttggtttac atcgttcgat tgattggatc atctattgcc
    16141 cttccagatt cattccctat cttgggagct ggagattggc gttcttacgt tttaccagca
    16201 gtcatccttg gtttgttggg tgctcctgtt acagccattt ggattcgtcg ttacatgatt
    16261 gacttgcaat ctcaagactt tgttcgtttc gctcgtgcaa aaggtttgtc tgaaaaagaa
    16321 atttcaaaca aacacatctt taaaaatgcc atggttccgc tggtttcagg aattcctggt
    16381 gccattattg gggttatcgg tggtgcaacc cttactgaaa cagtcttcgc cttcccaggt
    16441 atgggtaaaa tgttgattga ctctgtaaaa gcatctaata actctatggt cgttggtctt
    16501 gtcttcatct ttacatgtat ttctatcttc tcacgtcttt tgggagatat ttggatgact
    16561 attattgacc cacgtattaa attgactgag aaaggaggca aataatgtct acaatcgata
    16621 aagaaaaatt tcagtttgta aaacgtgacg attttgcctc tgaaactatt gatgcgccag
    16681 catattctta ctggaaatca gtgtttaaac aatttatgaa gaaaaaatca actgtagtca
    16741 tgttgggaat cttggtagcc atcattttga taagtttcat ctacccaatg ttttctaagt
    16801 ttgatttcaa tgatgtcagc aaggtaaacg actttagtgt tcgttatatc aagccaaatg
    16861 cggagcattg gttcggtact gacagtaacg gtaaatcgct ctttgacggt gtctggttcg
    16921 gagctcgtaa ctccatcctc atttctgtga ttgcgacagt gattaacttg gttatcggtg
    16981 tttttgtcgg tggtatttgg ggtatttcaa aatcagttga ccgtgtcatg atggaagttt
    17041 acaacgtcat ctcaaacatc ccacctcttt tgattgttat tgtcttgact tactcaatcg
    17101 gagctggatt ctggaatctg atttttgcca tgagcgtaac aacatggatt ggtattgcct
    17161 tcatgatccg tgtgcaaatc ttgcgctatc gtgacttgga atacaacttg gcgtcacgta
    17221 ctttgggaac accaaccttg aagattgttg tcaaaaatat catgcctcaa ttggtatctg
    17281 ttattgtgac aaccatgact caaatgcttc caagctttat ctcatacgaa gccttcttgt
    17341 ctttcttcgg tcttggatta ccgattacag tgccaagttt gggtcgtttg atttcggatt
    17401 attcacaaaa cgtaacaacc aatgcttact tgttctggat tccattgaca acccttgtct
    17461 tggtatcctt gtcccttttc gtagttggtc aaaacttagc ggatgctagt gatccacgta
    17521 cacatagata ggagtagaaa tgacaaaaga aaaaaatgta attttgactg ctcgcgatat
    17581 tgtcgtggaa tttgacgttc gtgacaaagt attgacagcc attcgcggcg tttctcttga
    17641 actagttgaa ggagaagtat tagccttggt aggtgagtca ggatcaggta aatctgtttt
    17701 gacaaagacc ttcacaggta tgctcgaaga aaatggtcgt attgcccaag gtagtattga
    17761 ctaccgtggt caggacttga cagctttatc ttctcacaag gattgggaac aaattcgtgg
    17821 tgctaagatt gcgactatct tccaggaccc aatgactagt ttggacccca ttaaaacaat
    17881 tggtagtcag attacagaag ttattgtaaa acaccaagga aaaacagcta aagaagcgaa
    17941 agaattggcc attgactaca tgaataaggt tggcattcca gacgcagata gacgttttaa
    18001 tgaataccca ttccaatatt ctggaggaat gcgtcaacgt atcgttattg ctattgccct
    18061 tgcctgccga cctgatgtct tgatctgtga tgagccaaca actgccttgg atgtaactat
    18121 tcaagctcag attattgatt tgctaaaatc tttacaaaac gagtatcatt tcacaacaat
    18181 ctttattacc cacgaccttg gtgtggtggc aagtattgcg gataaggtag cggttatgta
    18241 tgcaggagaa atcgttgagt atggaacggt tgaggaagtc ttctatgacc ctcgccatcc
    18301 atatacatgg agtctcttgt ctagcttgcc tcagcttgct gatgataaag gggatcttta
    18361 ctcaatccca ggaacacctc cgtcacttta tactgacctg aaaggggatg cttttgcctt
    18421 gcgttctgac tacgcaatgc agattgactt cgaacaaaaa gctcctcaat tctcagtatc
    18481 agagacacat tgggctaaaa cttggcttct tcatgaggat gctccaaaag tagaaaaacc
    18541 agctgtgatt gcaaatctcc atgataagat tcgtgaaaaa atgggatttg cccatctggc
    18601 tgactaggag gaaggaaatg tctgaaaaat tagtagaaat caaagattta gaaatttcct
    18661 tcggtgaagg aagtaagaag tttgtcgcgg ttaaaaatgc taacttcttt atcaacaagg
    18721 gagaaacttt ctcgcttgta ggtgagtccg gtagtgggaa aacaactatt ggtcgtgcta
    18781 tcatcggtct aaatgataca agtaatggag atatcatttt tgatggtcaa aagattaatg
    18841 gtaagaaatc gcgtgaacaa gctgcggaat tgattcgtcg aatccagatg attttccaag
    18901 accctgccgc aagtttgaat gaacgtgcga ctgttgatta tattatttct gaaggtcttt
    18961 acaatcaccg tttatttaag gatgaagaag aacgtaaaga gaaagttcaa agtattatcc
    19021 gtgaagtagg tcttcttgct gagcacttga ctcgttaccc tcatgaattc tcaggcggtc
    19081 aacgtcaacg tatcggtatt gcccgtgcct tggtcatgca accagacttt gttattgcag
    19141 atgagccaat ttcagccttg gacgtttctg tacgtgccca agtcttgaac ttgctcaaaa
    19201 aattccaaaa agagctcggc ttgacctatc tcttcatcgc ccatgacttg tcggttgttc
    19261 gctttatttc agatcgtatc gcagttattt acaagggtgt tattgtagag gttgcagaaa
    19321 cagaagaatt gtttaacaat ccaattcacc catatactca agccttgctt tcagcagtac
    19381 caatcccaga tccaatcttg gaacgtaaga aggtcttgaa ggtttacgac ccaagtcaac
    19441 acgactatga gactgataag ccatctatgg tagaaatccg tccaggtcac tatgtttggg
    19501 cgaaccaagc cgaattggca cgttatcaaa aaggactaaa ctaataatgg ttttataatt
    19561 tccatgtcaa tttttatgga aattaggctc tttgtcaact gtagtgggtt gaagtcagct
    19621 aagctcgaga aaggacaaat ttcgtccttt cttttttgat gttcaaagcg ataaaaatcc
    19681 gttttttgaa gttttcaaag tttcgaaaac caaaggcatt gcgcttgata agtttgatga
    19741 gattattggt cgcttccagt ttggcattag aatagtgtag ttgaagggcg ttgataatct
    19801 tttctttatc tttgaggaag gttttaaaga cagtctgaaa aataggatga acctgcttaa
    19861 gattgtcctc gataagttcg aaaaatttct ctggttcctt attctggaag tgaaaaagca
    19921 agagctgata gagctgatag tggtgtttca agtcttgtga ataactcaaa agcttgttta
    19981 aaatctcttt attggttaag tgcatacgaa aagtaggacg ataaaatcgc ttatcactca
    20041 gtttacggct atcctgttgt atgagcttcc agtagcgctt gatagccttg tattcatggg
    20101 attttcgatg aaactgattc atgatttgga cacgcacacg actcatagca cggctaagat
    20161 gttgtacaat gtgaaagcga tcaagaacga ttttagcatt cgggagtgaa acagtctaga
    20221 agactgtttc agcctgagcc tagaaatttg aaagcgaagc tgtttagcca agtcatagta
    20281 agggctaaac atatccatag taatgatttt gacgcgacat cggacggctc tatcatattt
    20341 aagaaagtga tctcggatga cagcttgtgt tctaccttca agaacagtga tgatatcgag
    20401 cttttcaaaa tcttgcgcaa taaagctcat ctccatctcc cgattgaaac agtcactccc
    20461 cggactgttt caacgtccca agacataatc ttaggcagat ttctaaaatt acactcaaag
    20521 tggaagtcat tgagctttcg aatgacagtt gaagttgaga tggaaagctg atgggcaata
    20581 tcagtcatag aaatcttttc aattaacttt tgagcaatct tttggttgat gatacgaggg
    20641 atttgatgat tcttcttgac gatagaagtt tcagcaacca taattttaga acaatgatag
    20701 cacttgaaac gacgctttct aaggagaatt ctagtaggca taccagtcgt ttcaagataa
    20761 ggaattttag aaggtttttg aaagtcatat ttcttcattt gacttccgca ctcaggacaa
    20821 gatggagctt catagtccag tttggcgatg atttccttgt gtgtatcctt attgatgatg
    20881 tctaaaatct ggatattagg gtctttaatg tctagtaatt ttgtgataaa atgtaattgt
    20941 tccatatgaa tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact
    21001 ttttttctac acaaaatagg ctccataata tccatagggg ggttacccac tacaaatatt
    21061 atagagccga aaaaggctga gatctggtgt ctcagtcttt tatttcttgc gttttgcaaa
    21121 atctacaaat ctaaattttt ctaacttatg gcgactttcg gtaaactgaa attggcgtcc
    21181 gtcttggaga tagacttttg atttaatcga aacgacataa gggtctttgc caatgtccat
    21241 gagaatcttg tctcggtcgc ttgagtggtc aatggtgatt tccttctgag cataatcaat
    21301 aaggagtttg aggccatttt ctatataaga atagatagac tgctcagcaa tttggcgagt
    21361 gagatttgga attagttcca tatccagata gtctgtatcc agaacggata ccagatcatc
    21421 caccacacgc tggcggacca ccttccaaac catccgaaac tctgggaaac cggttatcag
    21481 tgaggatttt ttatcaataa taatcttgtc cagactgacc acgttggttt tagagcgcag
    21541 tccaagttct ttaactagtt cttggtagct ggttaggttg gatacaggga aattgacggt
    21601 ttcttctttg acgacttgag aaccttgccc tcttatcttt ttgatcaatc cttcctcttg
    21661 gaggagagac agggcctttc ggacggtatc acgactcact tgatattgct ccataaggtc
    21721 gtgctcgcta ggaaggaaat ctccgacagc gtaagtctcg ttttgaatgg tttcttggat
    21781 ttgcttaaat aattgttggt atttcttcat tttgcctgct taaataggtt tttagtctag
    21841 tttaatgaac acctgtatct attttaccat acaagtgcta gaaaatttac aaaaaaacac
    21901 cctttttata ccaaacaagt tgcagacaag tttggtatcg tttacaatat acttatcaaa
    21961 tcaaacttgc tttgacaagt ataaggagaa tcaaatggga aaatttgaac aagaagccaa
    22021 agatctgctt caggcaattg gaggcaaaga aaatgtgact gccgtcaccc actgtgcgac
    22081 acggatgcgc tttgttttag gagatgataa gaaggctaat gttaaagcta tcgagtcaat
    22141 tccagctgtt aaaggaactt ttacaaatgc aggtcaattt caggtaatca ttggaaatga
    22201 cgtgcccatc ttttataatg attttacagc cgtttcaggt attgagggtg tttccaaaga
    22261 agcagccaag tctgcagcta agagtaatca aaacgtggtc caacgtgtta tgaccactct
    22321 ggcggagatt tttactccga ttattccagc cttgatagtc ggaggattga tcctcggttt
    22381 ccgtaatgtc ttggaaggtg tccattggtc gatgttggat ggcaagacca tcacagaatc
    22441 ctctcagttt tgggcaggtg tcaatcactt cctctggttg cctggtgaag ctatcttcca
    22501 gttcttacca gtagggatta cttggtctgt ttctcgtaag atgggaacca gccaaatttt
    22561 gggaattgtt ctcggaatct gtttggtatc gcctcagttg ctcaatgcct atgcggttgc
    22621 ttcaacgcca gcagctgata tcgcggcaaa ctgggtttgg aattttggct attttactgt
    22681 taatcgtatc ggttaccaag cccaagttat cccagccttg cttgcaggtt tgagtctgtc
    22741 ttatcttgaa atcttctggc gcaagcatat cccagaagtc atttctatga tttttgtacc
    22801 tttcttgtca ttgattccag ccttgatttt ggctcatact gttttgggac caatcggttg
    22861 gacaattgga caaggacttt catcagttgt cttggcaggt ttaactggtc cagttaaatg
    22921 gctcttcggt gcaatttttg gtgccctcta cgctccattt gtcatcacag gtctgcacca
    22981 tatgaccaat gccattgata cacaattgat tgcggatgct ggtggcactg ccctatggcc
    23041 aatgattgct ctttctaata ttgctcaagg ctcagccgtg tttgcctatt atttcatgca
    23101 tcgccatgat gagcgtgagg ctcaggtttc acttcctgca accatttcag cctatctcgg
    23161 tgttacagaa ccagctcttt ttggggttaa cgtaaaatat atttatccat ttgttgctgg
    23221 gatgactggt tcagcccttg caggcatgtt atccgttact tttaatgtaa ctgcggcttc
    23281 tattggtatc ggtggtttgc caggtattct ctctattcaa cctcaataca tgctgccatt
    23341 tgcaggaact atgctagttg cgattgttgt tccaatgctc ttgactttct tcttccgcaa
    23401 ggctggtctc tttacaaaaa cagagggcga tacgaacttg caggcagaat tcgttgctca
    23461 agaagaagca gaatttgtga accatgaacc agtagaactt acttcggtag aaattatcag
    23521 cccactaact ggccaagtga aagaattgag tcaagcgacg gatcctattt ttgcatcagg
    23581 tgtcatgggg caaggtctag tcattgaacc aagccaaggt gagttgacct ctccagttaa
    23641 tgggacagtg acggttcttt tccctaccaa gcatgccatc ggcattgtct ctgacgaggg
    23701 agttgaattg ctcatccaca tcggtatgga tacagtaggt cttgatggca aaggttttga
    23761 aagtcttgta gtccaaggag atcacgttac agttggtcag caactgattc gttttgatat
    23821 ggatgtcatt aaggctgcag gtctggtgac agaaactcct gttatcatca ccaaccaaga
    23881 tgcttataca gcgactattc ccggaactta tccgacaacg atccaagctg gagcatctct
    23941 catggtcgct acacgaatct aatactcttc gaaaatctct tcaaaccacg tcagctctat
    24001 ctgcaacctc aaaatagtgt tttgagcaac ctgtggctag cttcctagtt tgttctttga
    24061 ttttcattga gtataattga aatagcacaa atagggacgg aagactgctt cctccctttt
    24121 atcagaaaag gagaaacaga tgacacttga taaaggaaaa gtagtctatc aaatctatcc
    24181 aaaatcttac aaagacacca ctgaaaacgg tattggggat ttccgtggga ttatcgaaaa
    24241 aattccctat ttagccaaac taggtgtgga tatggtctgg ctcaatccat tctatccaag
    24301 ccctcaacgg gataatggtt acgatatttc agattatatg gcagtggatc ctctttttgg
    24361 tgatatggct gattttgagg aaatggtgtg tgtcggtaaa gagcacaaga ttgactttat
    24421 gctggacatg gtacttaatc attgttcgac agagcatgaa tggtttcaga aagccctagc
    24481 tggtgataag tattatcaag actttttctt catccaagac caaccaacag attggcagtc
    24541 taagtttggt ggttctgcat ggacgccttt cggggatact gggaaatact atcttcacct
    24601 atttgatgag acccaggctg accttaactg gcgcaattcc aatgtccgta aggagctttt
    24661 caaggttgtt aatttctggc gcgacaaggg tatcaaaggt ttccgatttg atgtgatcaa
    24721 tttgatcggt aaggacgagg tttcagtgga ctgtcctgaa aatgaaggga agccagctta
    24781 tacagacaaa cccatcgttc ataactattt gcgtatgatg aaccaagcca cttttggatc
    24841 tgacgatagc tttatgacag ttggggaaat gtcttctacc accatggaaa actgtgtcct
    24901 ctattcgtcg cctgatcgtc aggaattatc catgaccttt aattttcatc acctcaaggt
    24961 ggactataag gatggacaaa agtggacctt ggctcccttt gattttgaag agttgaagag
    25021 tctttaccat agttggggta aggaaatgag tgataaagac ggttggagtg ccctcttttg
    25081 gaacaatcac gatcaaccac gtgccttgaa ccgttttgtc gatattcaaa acttccgcaa
    25141 ggaaggagcc accatgctag cggctagcat tcacctgtca cgtgggacac cttatatcta
    25201 tatgggtgaa gaaatcggga tgattgaccc agactatgat tctatggctg attatgtgga
    25261 tgtcgaatcg cttaatgcct atcagacgct cttagaagaa ggaaagagtc agcaagaagc
    25321 cttccagatt attcaagcta agtcgcgtga taattcacgc attcccatgc agtgggatgc
    25381 ttcggaaaat gcaggatttt caacaggcac tccatggttg aaagctggta aatcctataa
    25441 atacatcaat gtagaaaatg aaatccaggg tccgattttc accttctatc aagacttgat
    25501 tcgactgcgt aaggaaatgc caatcatttc agaaggaagt tacaaaccag cctttgaaga
    25561 tagcaaacaa gtctacgctt ttgaacgcca gtttgaggat caaaagttac tagtgctcaa
    25621 taacttttat gctaaagaag tggaaatcga cttgccagca gtctaccaaa atggacagat
    25681 tttgatatca aactatgaag atgcagaagt gtctgagaaa attctactca aaccctatca
    25741 aacactggct atttatgtaa attaatactc ttcgaaaatc tcttcaaacc gtgtcagttt
    25801 tatctgcaac ctcaaagcgg tgctttgagc aacctgtggc tagcttccta gtttgctctt
    25861 tgattttcat tgagtataaa cttagcaagg agacctcttt ttcagaaaag cagcgttctt
    25921 tttgctgtct attccatccc tgaaagtgta gaacaaactg gtcagggtgg ctagtttgtg
    25981 gtataatgaa agggattcaa aaagaaacag gagaaaaatg atggatttac ttttagcaat
    26041 tgtattgatt gtgctagctt ttctaggagg agctcttgga ggaatgtact tggttcgtaa
    26101 gcaaatcgaa aaagaatttg ctgacaaccc acgtttgaat gctgaagcag ttcgtactct
    26161 tttgagtgca aatggtcaaa aaccaagcga agctaaggta caacaagttt accaccaaat
    26221 catccgccaa caaaaggcag cccttgctaa caataaaaag aaaaaataaa taaggaaaag
    26281 tctgggatga aagttccaga cttctcacta tgttggttat ggtttaggga tgagactttt
    26341 tccttgcatt ctattgatat ttgattatga ttaagagaga ggtagttgac attctatcaa
    26401 gctgtcggtc agttcgttca gtacaaggaa tcataatgaa cgatcaatca gaaaaaagac
    26461 tagaaagaag actgtatgga taatcgacca attggttttt tggattcggg tgtcgggggc
    26521 ttgaccgttg tgcgcgagct catgcgccag cttccccatg aagaaatcgt ctatattgga
    26581 gattcggcgc gggcgcccta tggcccccgt cctgctgagc aaattcgtga atatacttgg
    26641 cagctggtca actttctctt gaccaaggat gtcaaaatga ttgtcattgc ttgtaacact
    26701 gcgactgcgg tcgtctggga agaaatcaag gctcaactag atattcctgt cttgggtgta
    26761 attttgccag gagcttcggc agccatcaag tccagtcaag gtgggaaaat cggagtgatt
    26821 ggaacgccca tgacggtaca atcagacata taccgtcaga aaatccatga tctggatccc
    26881 gacttacagg tggagagctt ggcctgtccc aagtttgctc ccttggttga gtcaggtgcc
    26941 ctgtcaacca gtgttaccaa gaaggtggtc tatgaaaccc tgcgtccctt ggttggaaag
    27001 gtggatagcc tgattttggg ctgtactcat tatccactcc ttcgccctat tatccaaaat
    27061 gtgatggggc caaaggttca gctcatcgat agtggggcag agtgcgtacg ggatatctca
    27121 gtcttactca attattttga aatcaatcgt ggtcgcgatg ctggaccact ccatcaccgt
    27181 ttttacacaa cagccagtag ccaaagtttt gcacaaattg gtgaagaatg gctggaaaaa
    27241 gagattcatg tggagcatgt agaattatga caaataaaat ttatgaatat aaggatgacc
    27301 aggactggta tgttgggtct tatagtattt ttggtggcgt taacagtttg agcgactatc
    27361 agacagattt tcctctgttt gaattctcca aaatatttgg agatgaagag tatggtttcc
    27421 cgctttcagt tactgtttta cgctatggtt ctacctaccg tttgttctcc tttgtggtag
    27481 atatgcttaa tcaagaaatg ggacgaaact tggaagttat tcaacgtcat ggggccctgc
    27541 tcttggttga aaatgggcaa ctcttgtatg tagaattgcc taaagaaggg gtcaatgttc
    27601 atgatttctt tgagacaagc aaggtcagag aaaccttgtt gattgcgact cgtaacgaag
    27661 gcaaaaccaa ggaattccga gctatctttg ataagttagg ctacgatgtg gaaaatctta
    27721 atgactaccc tgacctgcct gaagtagcag aaacaggtat gacctttgaa gaaaatgccc
    27781 gccttaaggc agaaaccatt tctcaattaa cgggcaagat ggttttggca gatgattctg
    27841 gtctcaaagt cgatgtcctt ggtggcttac caggcgtctg gtcagctcgt ttcgcaggtg
    27901 tgggagcaac tgaccgtgaa aataatgcca aactcttgca cgaattggcc atggtctttg
    27961 aactcaagga ccgctcggct cagttccaca caaccctagt cgtagccagc ccaaataagg
    28021 aaagtttagt tgttgaagca gactggtcag gttatattaa ctttgaacct aagggtgaaa
    28081 atggctttgg ctatgatccc ctcttccttg taggagagac aggtgagtca tcagctgaat
    28141 taaccctgga agaaaaaaat agtcaatctc accgtgcctt agccgttaag aaacttttgg
    28201 aggtatttcc atcatggcaa agcaaaccat cattgtaatg agcgattccc atggcgatag
    28261 cttgattgtg gaagaagtcc gtgatcgcta tgtgggcaaa gtcgatgccg tttttcataa
    28321 cggcgattct gaactacgtc cggattctcc actttgggag ggcatccgcg ttgttaaagg
    28381 gaacatggac ttctacgccg gctacccaga acgtctggtg actgagcttg gttcgaccaa
    28441 gattatccaa actcatggtc acttgtttga catcaatttc aactttcaaa agttggacta
    28501 ctgggctcag gaggaagagg ccgctatctg cctctatggt cacttgcatg tgccaagtgc
    28561 ttggttggaa ggcaagatcc tctttctaaa tccaggctct atcagtcaac cacgaggtac
    28621 catcagagaa tgtctctatg ctcgtgtgga gattgatgat agttacttca aagtggactt
    28681 tttgacacga gatcacgagg tgtatccagg tttgtccaag gagtttagcc gatgattgcc
    28741 aaggagtttg agactttctt gttggggcag gaggaaactt ttttgacccc tgctaaaaat
    28801 ctagctgtgt tgattgatac tcacaatgcg gatcatgcga ccctcttgct cagtcagatg
    28861 acctataccc gtgttcccgt tgtgacagat gaaaaacagt ttgttgggac gattggactc
    28921 agagatatta tggcttatca gatggagcat gacttgagcc aagaaatcat ggcggatacg
    28981 gatatcgttc atatgacaaa aacggacgta gcggttgttt cgcctgattt caccattacg
    29041 gaggtcttgc acaagctagt agatgagtcc ttcttaccgg ttgtggatgc agagggtatt
    29101 ttccaaggga ttattacgcg caagtccatc ctcaaggccg ttaatgccct cttgcatgac
    29161 tttagtaagg aatatgagat tcgatgccaa tgagagacag gatttcagcc tttttagagg
    29221 aaaagcaggg cttgtctgtc aattccaagc agtcctataa gtatgatttg gagcaatttt
    29281 tagacatggt aggtgagcgg atttctgaga ccagtctcaa gatttaccaa gcccagctag
    29341 ccaatctaaa aatcagcgcc cagaagcgaa agatttcggc ctgtaaccaa tttctatact
    29401 ttctctatca aaaaggagag gtggacagct tttaccgctt ggaattagcc aaacaagctg
    29461 aaaagaagac ggaaaagcca gagattctat acctagactc tttttggcag gaaagcgacc
    29521 atccagaggg ccgcttgcta gcgctcttaa tcctagaaat ggggctcttg cccagtgaga
    29581 ttttagccat caaggttgcg gacatcaatc tggattttca ggtgttgcga atcagcaagg
    29641 cttcccaacg gaggattgtc accattccca cggccttgct ttcagaattg gaacccttga
    29701 tggggcagac ctatcttttt gaaagaggag ggaaacccta ttctcgtcag tgggcctttc
    29761 gtcagttaga atcttttgtc aaggagaaag gttttccatc cttatcagct caagtcttac
    29821 gtgaacagtt tattctaaga caaatagaaa acaaggtcga tttgtacgaa attgcaaaaa
    29881 aattaggatt aaaaacagtc ctgaccttag aaaaatatag ataatggata ttaaattaaa
    29941 agattttgaa ggacccctgg acttactctt gcatctggtt tctaagtacc agatggatat
    30001 ctacgatgtg cccattacgg aagtcatcga acagtatcta gcctatgtct caaccctgca
    30061 ggccatgcgt ctggaagtga cgggtgagta catggtcatg gctagtcagc tcatgctgat
    30121 taagagtcgt aaactccttc cgaaggtagc agaagtgaca gacttggggg atgacctgga
    30181 gcaggacctc ctctctcaaa tcgaagaata tcgcaagttc aagctcttgg gtgagcactt
    30241 ggaagccaag caccaagaac gggcccagta ttattccaaa gcgccgatag agttgattta
    30301 cgaagatgcg gagcttgtgc atgacaagac gaccattgac ctctttttgg ctttttcaaa
    30361 tatcctagcc aagaaaaaag aggagtttgc acaaaatcac acgactatct tgcgggatga
    30421 gtataagatt gaggacatga tgattattgt gaaagaatcc ttgattggac gagatcaatt
    30481 gcgcttgcag gatttgttca aggaagccca gaatgtccaa gaggtcatca ccctcttttt
    30541 ggcaacccta gagttaatca aaacccagga gctgatcctc gtgcaagagg agagttttgg
    30601 agatatctat ctcatggaaa agaaggaaga aagtcaagtg cctcaaagct agacttgata
    30661 gagaggaaag atgagtactt tagcaaaaat agaagcgctc ttgtttgtag cgggtgaaga
    30721 tgggattcgg gtccgccagt tagctgaact cctctctctg ccaccgacag gcatccagca
    30781 aagtttagga aaattagccc agaagtatga aaaggaccca gattccagtt tggctttgat
    30841 tgagacaagt ggtgcttata gattggtgac caagcctcaa tttgcagaga ttttgaagga
    30901 atactctaag gcgcctatca accagagctt gtctcgggct gcccttgaga ccttgtccat
    30961 tattgcctac aaacagccga ttacgcggat agaaattgat gccatccgtg gggttaactc
    31021 gagtggagcc ttggcaaagt tgcaagcttt tgacctgata aaggaagacg ggaaaaagga
    31081 agtattgggg cgccccaacc tctatgtgac tacggattat ttcctagatt acatggggat
    31141 aaaccattta gaagaattac cagtgattga tgagcttgag attcaagccc aagaaagcca
    31201 attatttggt gaaaggatag aagaagatga gaatcaataa gtatattgcc cacgcaggtg
    31261 tggccagtag gagaaaagca gaagagctga tcaagcaagg tttggtgacg gttaacggcc
    31321 aagtggtgcg tgaactagca accactatca agtcaggcga caaggtcgaa gttgaaggtc
    31381 aacctatcta caacgaagaa aaggtctatt atctgcttaa caaaccacgc ggtgtcattt
    31441 ccagtgtaac agatgacaag ggtcgcaaga cggttgtcga cctcttgccc aatgtcaaag
    31501 aacgtattta ccctgtgggt cgtttggact gggatacatc gggtgtcttg attttgacca
    31561 atgatgggga ctttacagac gagatgattc accctcgtaa tgagattgac aaggtttatg
    31621 tcgcgcgtgt taaaggtgtg gccaataagg acaatctccg ccccttgacc cgtggtcttg
    31681 agattgatgg taagaaaacc aagccagctg tttatgaaat tctcaaagtg gacccagtca
    31741 aaaatcgctc tgtggtgcag ttgaccatcc atgaagggcg taaccatcag gttaaaaaga
    31801 tgtttgaagc tgttggtctc caagtagata agttgtctcg gactcgtttc ggacacctag
    31861 acttgacagg actccgtcca ggagaatccc gtcgtcttaa taaaaaagaa atcagccaac
    31921 tacacaccat ggctgtaact aagaaataat gaaacgaatt ttaatagcgc ctgtgcgctt
    31981 ttaccaacgt tttatctcac cagtctttcc cccctcttgt cgctttgagc tgacttgttc
    32041 caactacatg attcaggcta ttgaaaaaca tggttttaag ggggtattga tgggcttggc
    32101 tcggatttta cgttgtcatc cctggtcgaa aacaggtaag gaccccgttc cagaccactt
    32161 ttcccttaaa cgaaatcaag aaggggaatg aggtggggta aatagatttc aaaatgataa
    32221 aaacgcatcc tatcaggttt gagtaaactt gataggatgc gttttagaat gtcaaaattt
    32281 tatactcttc gaaaatctct tcaaaccgct tcagctttca tctgcaacct caaaacagtg
    32341 ttttgagcaa cctgcggcta gtttcctagt ttgctctttg attttcattg agtattaaat
    32401 tgagtttgaa gtggcttatt tcaaagcttt ttgtatgtct tcaatcatga gttttgttga
    32461 ttcaagtccg cctccgctta gataccagag gtctggtgtt agttggataa tcttaccatt
    32521 tttagcagca ggtgtttcag cgataagggc attttctagg acaccgtcgt tgctagagtt
    32581 gtccccaccg atggcaaggg tacggttgat gacaaagagg atgtcagggt tgatttcttt
    32641 gacactttca aagctgactt cttgtccgtg gcgtgagtct tcaaattttg tatcagttgg
    32701 tttgaatttc aaggtttggt acaagaaaga gaaacgagat ttggcaccaa aggctgccat
    32761 ttttccttca ttaaggagga tcgcaagggc ttttttgtca gagctttcat ttttagtagc
    32821 gacttcttgg atgctcttgt ctagcttggc caattcttcc ttggctttct gtgtaccagt
    32881 ttcgccgaag gcacttgcta aggattcgat attagccttg gtagaagtcc agtagtcgtc
    32941 cttgcttgct tggaagagaa cggttggggc gatttctttg aatttgtcta cgaatttttg
    33001 tgtacgtggt gaagcgataa tcaaatcagg ctcaagggcg gcgatagctt ctaaatcagg
    33061 ttctttcata gaaccaacat ttttgacagt tcccactagg tcttttagat aagtcggaac
    33121 agtttttgta ggcattccga cgatattttt ttcaaatcct aaagcgcgaa tagtatccgc
    33181 aacgccgagg tcaaaggtca caatcttttc aggaactttg gaaagtttga cctcgtccag
    33241 tgaactttta atggttacct ctgttggagc agagctactg gtctctgtct gactagtgct
    33301 tgagtttgta ctacatgcac caagtaggag caagaagctg gccactaggg cagtgaaata
    33361 aagtttaagg gatgttttca taatttctcc tttttaaaat gtgataacga tttagggagt
    33421 ctcttgatct tattgactaa gagactgaag gttctctaac ttgagctttt atgttactag
    33481 ctatagatac agatcttttt gtcattgata tcagctagcg tgatgggaat ctcataaagt
    33541 tgactgagta ggtcagcctg catgatttga tcggttcttc ccttgctaaa gacctggccg
    33601 tccttgaagg cgacaatttc atctgcatac tgactggcca tgttgatatc gtggaggacg
    33661 atgataatgg tcttgccgag ttcctccacc agtcgtcgaa gaatctgcat catgctgacg
    33721 ctttgcttga tatcgagatt gttgagtggt tcgtccagca agataaagtc cgtatcctgg
    33781 gccagtacca tagcgataaa gacgcgctgg agttgccccc ctgacaggct attgatgtag
    33841 cggtctttta agttggtcag ttccaaatag ttcagagttt ctcggatttt ttcccagtct
    33901 tctgatctaa gtcgacctcg gctgtaggga aaacgtccaa aactgaccag ttcttcaaca
    33961 gtcaatttgg cttggtaatt gattttctgt tttaggatgg ttagttcttg agccagttct
    34021 tgcgaattcc agctctcgat ttcacgtcct ttgatactga gaactccctg atctttcttg
    34081 gttagtctgc tcatgatgga gaggagagtc gattttccag caccatttgg accaataaag
    34141 gcagtcagtt tttgaggact gactttaagc gaaatgcctt gcaaaatatc ctgtttttga
    34201 atggatttgt caatgttttc cagtttcact gacgagacct cctatatagt aagataaaga
    34261 ataagaagcc acccacactc tcaatgatca tactgatacg aatttccagt gcaaagactc
    34321 gttcaatcaa ggcttgcccc aaggttaagc taataaatcc aaccagaatg gccactataa
    34381 agagtaactt gtgctgatag tctttgacaa tcaggtaggt gaggttggcc agcataaagc
    34441 cgaagaaggc cataggtcct accaaggcag tggccgttga ggtcaaaagc acgattcccc
    34501 agaggagctc tttctgttct ttttcaacat cgagtcccaa tatctgagcc gtttctcttt
    34561 gcaggtgcaa gacatctaga acgactgctt ttcgaaagaa aaagattgtc aaagcgagga
    34621 tgatcagaga accgatggct aggatggaag tgttgagatg ttgaaaggag gcaaaaagac
    34681 tattttgcag tttatcgtat tcgtttggat ccattaggac ttgaaggaag gtgctgatat
    34741 ttcgaaagag acttctgagc gctagacaga tcagcaggat gaagaccagg tcttgcttca
    34801 tcagtgtctt caagtaacct tgtaaggcga gaaagaagag ggactggaca agaagtaaga
    34861 ctaggaattc taagataggg gatttgccaa gttgaagaaa cttgctttca aaaaccagta
    34921 gtagggtttg tagtaggacg tagaaggatt caattcctaa aatactaggc gtcaggaagc
    34981 gattttccgt cagggtttga aaactaatgg tcgaaatccc agtcgcgatg gctaccaaga
    35041 gataaacgat gatcttttgg gaacgcaact tccaagcaaa ggctgacaag tgagtgatgg
    35101 gccaaaagta gagaagacaa gctccgatgg caagaataat gagaatccag aagagcttgg
    35161 tatgtttgct tttagtctgc atcttttcgt ccccctctcc agagaagtag gataaagacg
    35221 agactaccga tgattcctag caagagactg acagacaact catagggcct aatcagaact
    35281 cgggatagga tatcgcaagc cagaactaga ttggcaccaa ccagtgcgac catgagtttg
    35341 gtttgactta gattatctcc atagcgcttg cgaacaagat tgggaacgat aactccgaga
    35401 aatggtaggc cccccacggt aatcatggtg acgcttgtcg ttagcgccac cagaaagagg
    35461 gccagttttt caagtaggga gtaggaaatc cccaaactct cgctggtttc tttccctaga
    35521 ttcatgatgg tgaaggtttg ggataatttc caaacggtta tcaggatgat gaggcctaag
    35581 aagagccact catactgatg ggtctgaatc atggagaagg agccctgggt ccaggcagtc
    35641 atactctgaa ccagattgaa acgataggcg ataacttctg tgactgagcc gataatcccg
    35701 ctatagatga tcccaatcag aggcaacatc cacctttcct ttacagtaaa aatggtcata
    35761 aaggctagga agaagagggt gaatacgatg gatgaaacaa aagcgaagag catcttttgg
    35821 gtcagactag ccgatggaaa gacaaaaagg ctcagcacca ttcccagttt ggcggcttca
    35881 gtcgttccaa ctgtactcgg tgcagcaaac tgattttggg taatagtctg catgagaagg
    35941 cctgccatac tcatactaga ggcagtcagg agaatactga tagttcttgg gagacgggac
    36001 tcttgaaaga ggagccaggt ctgctggtcg aaatcaaata gctttcccca tgaaaaatca
    36061 ctggtcccaa tgctaataga gagaaagact aggagtagaa gtaagccaat taaataatga
    36121 gaaagtttca taccccgtcc cttcatgtag atttggtatc gaaagatacc tgcggatata
    36181 aatgtaacat tatttttcta atctgtcaat aaaatttctg acaatttaat aaatacaaca
    36241 aggagagagc aacaaaactt tctcctttgt tatcctattc taaaatgttt ttaccttaat
    36301 ctgataaaat aatatcttcg agggagtagc tagccgtcca atcaagatat tgtttagctt
    36361 ttgaagcatc tgctaggaca ctggctgggt cactagcacg tcgagcaaca atctcgtgtg
    36421 ggatttttta atttagtaat tcttcagcag ttttaaagat ttctttgata gtatagcctt
    36481 ttttagttcc taagttaaag atttgagaag aactgtcttc ttgaaatagg tagttcattc
    36541 ctttaacatg agcctatgca aggtccaaga cataaatgta atctcgaata catgaaccgt
    36601 cacgtgtatc gtagtcatct ccaaatattt ttaagctatc attttgtccc aatgcggtct
    36661 tgttgatatt tggaatgatg tgagttggat ttttcacacg cagaccgttt gaagcatcca
    36721 tttcagcccc agcaacatta aagtaacgga aaataacata tttccagtcg tagcgattgg
    36781 ccatccagta aatcattcgt tcgcccatca gttttgtctc tgcataaggg ttgacagggt
    36841 cgagcagggt atcttcagtc accggcttgt caatacagtt atttccatag agagaagcag
    36901 tcgaagagaa catgattttt tgaatgccaa cttcagataa gactttgaga acttggttca
    36961 taccagcaac gttggcagtg aagtatttac ttggattttc aatactttcg ctcacaacaa
    37021 tttcacctgc acaatggagg acagcatcaa tctgattttc ttctaagtaa acctttaagg
    37081 cgctagcatc ataaacatcc agttctttaa agctagcacg actatccaca gccgctcgat
    37141 ttcctgtgga gagattatcg aggacatgca ccttatagcc agcatttaaa agagctttaa
    37201 cggtatggga gccaatgtag ctagtcccac ctgtaacaag aattgttttg gtcatgattt
    37261 tttccttttc tagttttgta ctatagtaa
//
LOCUS       DAVKBC010000016        36635 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVKBC010000016 DAVKBC010000000
VERSION     DAVKBC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.016"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(113..823)
                     /locus_tag="VWX64_000953"
     CDS             complement(113..823)
                     /locus_tag="VWX64_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU9190440.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(826..2517)
                     /locus_tag="VWX64_000954"
     CDS             complement(826..2517)
                     /locus_tag="VWX64_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9190441.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLIIKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(2529..3539)
                     /locus_tag="VWX64_000955"
     CDS             complement(2529..3539)
                     /locus_tag="VWX64_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190442.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(3642..4709)
                     /locus_tag="VWX64_000956"
     CDS             complement(3642..4709)
                     /locus_tag="VWX64_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9190443.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(4734..5393)
                     /locus_tag="VWX64_000957"
     CDS             complement(4734..5393)
                     /locus_tag="VWX64_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU9190444.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIYMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAKLTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(5602..5886)
                     /locus_tag="VWX64_000958"
                     /pseudo
     CDS             complement(5602..5886)
                     /locus_tag="VWX64_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(6134..6430)
                     /locus_tag="VWX64_000959"
     CDS             complement(6134..6430)
                     /locus_tag="VWX64_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190445.1"
                     /translation="MVKINKICSIQGSSVENEDTVGSQNQYFWIIDGATDLYNSKEEI
                     GYSVSEVVHILSKSLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(6414..8540)
                     /gene="pfbA"
                     /locus_tag="VWX64_000960"
     CDS             complement(6414..8540)
                     /gene="pfbA"
                     /locus_tag="VWX64_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU9190446.1"
                     /translation="MKYFVPNEVFSIRKLRVGTCSVLLAISILGSQGILADEVVTSSS
                     PMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNSISSNGTIRSNS
                     QLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAVGDGIHDDRQAI
                     QDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILNGINIKNHPSIV
                     FMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLINSSGAFAIGNS
                     NNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEP
                     LTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKIL
                     NNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLL
                     DLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNI
                     ELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSSKYISFIKSNANGKE
                     PVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNGEFNS
                     SKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSNKI
                     MELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(9704..10930)
                     /locus_tag="VWX64_000961"
     CDS             complement(9704..10930)
                     /locus_tag="VWX64_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU9190447.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLY
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(10973..11665)
                     /locus_tag="VWX64_000962"
     CDS             complement(10973..11665)
                     /locus_tag="VWX64_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU9190448.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALIL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(11838..13589)
                     /locus_tag="VWX64_000963"
     CDS             complement(11838..13589)
                     /locus_tag="VWX64_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190449.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     VNMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(13579..15324)
                     /locus_tag="VWX64_000964"
     CDS             complement(13579..15324)
                     /locus_tag="VWX64_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190450.1"
                     /translation="MSIIQKFWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINSLTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(15530..15907)
                     /locus_tag="VWX64_000965"
     CDS             complement(15530..15907)
                     /locus_tag="VWX64_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU9190451.1"
                     /translation="MKRLIDGKPTFLIKNGNIDPEACRSVGLSASDVALKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYK"
     gene            complement(15979..16435)
                     /locus_tag="VWX64_000966"
                     /pseudo
     CDS             complement(15979..16435)
                     /locus_tag="VWX64_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            16569..17396
                     /gene="xth"
                     /locus_tag="VWX64_000967"
     CDS             16569..17396
                     /gene="xth"
                     /locus_tag="VWX64_000967"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU9190452.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            17408..17551
                     /locus_tag="VWX64_000968"
     CDS             17408..17551
                     /locus_tag="VWX64_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU9190453.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            17551..17790
                     /locus_tag="VWX64_000969"
     CDS             17551..17790
                     /locus_tag="VWX64_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU9190454.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      18174..18269
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18620..19201
                     /locus_tag="VWX64_000970"
     CDS             18620..19201
                     /locus_tag="VWX64_000970"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU9190455.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            19201..20463
                     /locus_tag="VWX64_000971"
     CDS             19201..20463
                     /locus_tag="VWX64_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU9190456.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKIANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(20513..20974)
                     /locus_tag="VWX64_000972"
     CDS             complement(20513..20974)
                     /locus_tag="VWX64_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEU9190457.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(20971..21735)
                     /locus_tag="VWX64_000973"
     CDS             complement(20971..21735)
                     /locus_tag="VWX64_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU9190458.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCDIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(21916..22320)
                     /locus_tag="VWX64_000974"
     CDS             complement(21916..22320)
                     /locus_tag="VWX64_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU9190459.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(22390..23871)
                     /locus_tag="VWX64_000975"
     CDS             complement(22390..23871)
                     /locus_tag="VWX64_000975"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU9190460.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKTL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(23890..25068)
                     /locus_tag="VWX64_000976"
     CDS             complement(23890..25068)
                     /locus_tag="VWX64_000976"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU9190461.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLERDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYKEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            25233..26240
                     /gene="galR"
                     /locus_tag="VWX64_000977"
     CDS             25233..26240
                     /gene="galR"
                     /locus_tag="VWX64_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU9190462.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(26286..27323)
                     /locus_tag="VWX64_000978"
     CDS             complement(26286..27323)
                     /locus_tag="VWX64_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9190463.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKVGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(27324..27677)
                     /locus_tag="VWX64_000979"
     CDS             complement(27324..27677)
                     /locus_tag="VWX64_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU9190464.1"
                     /translation="MNIKSASDLLEISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQIQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(27921..28811)
                     /locus_tag="VWX64_000980"
     CDS             complement(27921..28811)
                     /locus_tag="VWX64_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU9190465.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            28944..29480
                     /locus_tag="VWX64_000981"
     CDS             28944..29480
                     /locus_tag="VWX64_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9190466.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(29647..30453)
                     /locus_tag="VWX64_000982"
     CDS             complement(29647..30453)
                     /locus_tag="VWX64_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU9190467.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(30798..32318)
                     /locus_tag="VWX64_000983"
     CDS             complement(30798..32318)
                     /locus_tag="VWX64_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU9190468.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITENQMSQLNYQVGVEGKSAEQVAKEFLQEQGLLKK"
     gene            complement(32311..33039)
                     /locus_tag="VWX64_000984"
     CDS             complement(32311..33039)
                     /locus_tag="VWX64_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190469.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            complement(33054..33818)
                     /locus_tag="VWX64_000985"
     CDS             complement(33054..33818)
                     /locus_tag="VWX64_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU9190470.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAGAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAKYDIFRLKNGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(33822..34265)
                     /locus_tag="VWX64_000986"
     CDS             complement(33822..34265)
                     /locus_tag="VWX64_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9190471.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(34947..35243)
                     /locus_tag="VWX64_000987"
     CDS             complement(34947..35243)
                     /locus_tag="VWX64_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9190472.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEGLFKML"
     gene            complement(35265..36329)
                     /gene="pepA"
                     /locus_tag="VWX64_000988"
     CDS             complement(35265..36329)
                     /gene="pepA"
                     /locus_tag="VWX64_000988"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU9190473.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
BASE COUNT        11053 a         8054 c         6359 g        11169 t
ORIGIN      
        1 attttataat ctttcataaa aacctctgag caaaaatcta ctcaaaaatt agatgattaa
       61 aacatctaaa aaacaaaagg acaaaaacat ctgtcccttt gtttactaaa tttcagctaa
      121 tttcttcgac ataaataaca cctacaatat tagcaatttc ttccatcagt cgaagatgtt
      181 caaatctacc tgataattcc agagtaataa atgacgctat ttttttatct ggaacatcaa
      241 agtattcaat tctgtcagaa ttaacatctc caaacgctgt tcttgaatcg gtcattctga
      301 taccattttc tgcacaataa accaatacac gattataggc ttctgtagat ttaaccacta
      361 tatacaattc aatcatttta gaacgatttt gcagatattt ttttagtggt tggaacatgg
      421 atatcacacc ccaaacagaa atagctacta aaagagctcc ctcataaaaa cctactccaa
      481 tagctaatcc aattcctgcc gaagcccaaa tgcctgctgc agttgtcaga cctgtaattt
      541 tctttttatc tgtaataaga atcgttccag cgcctagaaa acccacacct gatataactt
      601 gagctcctaa tcgtgtagga tctcctgtcc caaatttata agatacgtat tcattcgtca
      661 tcataatcaa acatgcagct agacaaacaa tactataagt tcggatgcct gcaggctggg
      721 atttgctccc tctctctaaa ccaattatac taccaatgac tactgataaa acaatcctga
      781 caactatttc aatatttgat aacccaagac tagtggctgt catgattatt tccttacttt
      841 acgccccggt ctttgtgtga agtataatac cgttccagaa ataatcatca gaacaattgt
      901 ataaacaaat accagagctt gtgcattaga tgttgctgtt tcatcacctg cagatcgaat
      961 cgtaatacct aatggttgag ctaggggatg gtaaaggaat acagataagt cgaagtcagt
     1021 taataaagag ttaaagttta aagcaataac agagagaaca accggtaaaa taaatggaat
     1081 gataaccttc atcatagtat aaaaaggtga agcacccata cttcttgctg catcttccat
     1141 ctcatcatca acactaaata aaatagcacg taccattcta taagaaaatg ggatttttac
     1201 aactatatat gcaataagta gaattaccaa actacctacc aaaatctgat tcaagacaag
     1261 aaattgtggc tgattaaaag taaataataa acttactgct aaaagtgtac ttggtagtaa
     1321 ccaaggaagt agagcaccat attcaaataa gaaatcaaaa cgagatttat gttttctgac
     1381 aacacgagca aatacaactg cgagaattgt tgctgttgtc gcagcaataa tagaataaat
     1441 aaagctgacc aagaatggag agaatgccgc actattacta aagaataagc gataattttc
     1501 taaagtaaag tttgataatg ttaagttacc tgtttgaatt gcaactggat ctgtaaatga
     1561 gtataatact ataaaaatta gtggaagcat gaaaactgtg aacaatccat atgctacaat
     1621 gtgagcaatg atattccaag gcttagacgc aattttttgt tttttaagag gcgctttagt
     1681 cttagagata gaaatataat ttccaccttt ttctatctta ttcatgatag taagcaaaat
     1741 tgtagttgca atacctaaaa taattgcaag taaggcagct aaatcacgag aattccccat
     1801 ccctgcaaat gtaataatca ttggatttat agtttgaaat tctttaccac caacaatcat
     1861 gggtgctgct actgcagata aaccactaag aaaaaccata atagtaagtg caaatagagt
     1921 tggaattaag gttggtaaca ctacttttcg gaaaacagta aatggttttg ctcccatatt
     1981 tcgagcagcc tcaatagtgt gatagtcaac gcttcgaatt gtatttgtta aaaacaatgt
     2041 atgattagca gttcctgaaa atgtcataat gaataagact gcaccatacc caataaacca
     2101 gttagagtct aaagaaggga taacattttg taaaaatttt ataatcaatc cataaggacc
     2161 atagacaaat ttatatccag tcgctaaaac cactcctcca taaattaaag aggtcatata
     2221 acctaatttt aaaattttag cacctttaat atcaaagtac tctgtaaata gaacacaaag
     2281 aatacctacg acattaactg taataatgag tgaaaatgct aacttaaaac tgttcataat
     2341 actctgaagt gccctctgag attttagaac acgatgtaca gcatcaaggg aaaattctcc
     2401 tccttttaca aatacattca ctactagatc aaagtttgga taaataataa atgttactaa
     2461 gaaccagatt aaccctaaac gaataagcca atcttttaaa tttaatttat gacgcatact
     2521 gcacctcctt aaaattgcag aacgtctgat ggtgtgataa ataattccac actttctccg
     2581 acagatctaa tagcagcctg actatcaata cttgttacat taagaatctg actttcagaa
     2641 acttttattg tatagtgaat tgtaactcca gaaaactcaa catcaataat tgtccctttt
     2701 agaataaaat cttgttcagt ttcacgattg aatcgaactt tctctaatcg aatgtatcct
     2761 tttttatcct ctaagaaaac gcttgtattt ttcaataata cttcgtggac tgtttcatcg
     2821 gtcaaaacat taatatctcc aataaaatca catacaaatt cagtttgaga attatgataa
     2881 atctctactg gtgtaccgac ctgttcgatg tatccattgt taaagactgc aattctatca
     2941 gataaagtca aggcttcctc ttgatcatga gtaacatata aagtagtaat acctaactct
     3001 ttttgaagtc ttttcaactc ttttctcaaa tctacacgta attttgcgtc aaggtttgac
     3061 aatggttcat ctagacaaag aattttaggt tcaagaacca gagcacgagc caatgctacc
     3121 ctttgttgtt gacccccaga taattctgat acattacgct gtaactgttg atcagagatc
     3181 ttaatttttg ctgccactgc tgatacttta gctttaataa catctggagc taccttctta
     3241 acttttaaac caaatgcaat attatcaaaa acagtcatag ttggaaatag cgcataagat
     3301 tgaaatacaa taccaattcc acgcttttca ggttccaaat gagtgacatc tgttccatta
     3361 acttcaatac ttcctgatga tggatctaaa aaacctacca atgctctcaa agtagttgat
     3421 ttaccacatc ctgaaggccc aagaaatgta aagaattccc cttcatgtat atctaaattc
     3481 agattatcaa ttgcaacaaa atcaccatat ttaatttgaa tattatcaaa tttaatcatc
     3541 tcactaactc cctctattac taaaccaaaa gcctctcttt atttcttcct taaatttaga
     3601 aataatagag agacttggac ataaaaaata actcttattt cttattttac gtattctaat
     3661 tcagcttttt ctacccattc atccaaatgc tttccaacag cttcccagtc aatattttgt
     3721 ggtttcactt gatcaacaaa ttttttcgta tcttcaggta actcttttag ggcatcttta
     3781 ttggcaggga tagagccaaa ttttttacta tattctactt gaatttctga ttgaccaaac
     3841 caatcaataa attctttagc taacgcttgt tttttactag tgcttaaaac catagtttgt
     3901 tcagttacaa atggtacacc aatctcagga gtcataactt tgaattcaac attttgttct
     3961 ttttgtccaa ttaacgctcc agaaccccag atcataccgt attgaattgg gctttcttta
     4021 tctaacgctt taacaactga gctttcacct ttttgaagag tataggcatt tgcaaagtat
     4081 tcttttgcaa cttcccatcc tttttctgat acgcctaaat ctcctttttc atcaaggtaa
     4141 cgaactaaga tacttgctag aattgcccgt cctgtaccac cttgaagacc ataaattgaa
     4201 tatttacctt tatacttact acctaattca gtccaatctt taggcatttc ttttacatca
     4261 ggcgccccaa ttaaaactaa tggttgaaca atcacaggat tataataatt atctttatct
     4321 gataaagatt gatcaatttt atctaaccat ttaggcttgt actgtactag taatttttga
     4381 tctctaattt tatttgagtc aacagcacca attccaaata ccatatctgc aactgcatta
     4441 ttcttctcag caataacacg gtctgctaat tgagcgccag cgatatcaac catttttata
     4501 ttaaaaccag cttcttttgc tttagcagtt aaccaatcac cacgaccatt tgagactgag
     4561 ttcgaataga taactaattc ttgactttta tcagcttttt cttcagatga agaagcagtc
     4621 gtagaatttg aacctccaga gcaagcagca agtgtagtaa gagcaactcc cgttgcaagt
     4681 acagtagacc aaactttcat ttttttcatg ataagttctc cttttttatt attttattta
     4741 aatttttcgt gatatggaac aaattgtctc atatcttcaa atacagtata gtcaatacgg
     4801 tttacagtaa tagttggaat cttctctaat aaaatttcag ttaattttgc tctgacttta
     4861 gtaaactctt cttcctcctc ttcggttaga ggaatccgaa gatacccaat tgaaatatgg
     4921 aattgatatc tatcatgatt agggaaacaa acacctgctt tttctgagac ataagtacga
     4981 atttcttcta atctctttgc agaagcttca tctgcaggtt caactagtat gttttgtttt
     5041 cccatttcag ttatacgcat ataaatttct tcatccaaca atggaaaaat ttcaagttgt
     5101 ttagcaaagt aatcatgtat ttcctgtaaa ggtgtatcta gaggaagatt actgctccaa
     5161 aactccgttt cacgattttc atggcacaac aattcaatta cagtcatgtg aatagaattc
     5221 cttggagtta aagtaaactt atcgataaat ggtaattctc tataacgtga ttgaataata
     5281 tcaacaactt ccatcaaatc ttgtttagta taaagatttg ctacaactgt attcccaggg
     5341 aaatgattaa attccccatt ctctttgaac ttaatttttg ttaagttttt catataaaga
     5401 ccttcttttt tatatttgac atcggtgtca catgtttaca ttatacaatg aaaccgtttc
     5461 ctttgtcaag cgctgtcaaa catttttttt aatttatctt tcattaaata tgcatttcat
     5521 taaaaggtta agtaattttt ccaaaataca gcactcatat agacagtatc atcaattata
     5581 gccattggga ttttttgatt gctaattcca tgtatctcta cacatgtctt caatcgattt
     5641 tgttgtcctc caatttaatt ccttatatgc tttgtctgca tttgcataac aagttgcaac
     5701 gtctcctgaa cgtcttggaa ctattttata aggaataggg atcttattaa cactttcaaa
     5761 tgtatttaca agttgtaata cactagtgcc ttctcccgag cataggttat agatataaac
     5821 atctgttttt tcagatactt tttctaaagc ttttatatgt cctattgcta aatctactac
     5881 atggatcttt tatctcattt ttcccttttt caaataagtt atctactcta tgatcagtta
     5941 tttccatttc gtttactaac atgacgcagt cacctagcat catatactcc aacttttttt
     6001 ctgaaagttt agcaaatata aaagcaaatg ttggtaagcg ataatatagt atattgaaac
     6061 tagaatagta cacctctact tctaaaatat tgttagaaat cgatttgact gtcctgattg
     6121 atttgtccta ttattatttc attttgctat actctgttaa ttcatatgag tttaaaccga
     6181 tttcatcttt aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt
     6241 tacaattaac cgacaaactt tttgataaaa tatgtacaac ttctgagact gaataaccta
     6301 tctcctcttt agaattatat aaatctgtag ctccatcaat aatccaaaaa tactgatttt
     6361 gtgaacctac agtatcctca ttttctacgg aacttccttg tatcgaacaa attttattta
     6421 tctttaccat aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt
     6481 aaaaatagtt ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact
     6541 atttctttag atttattaat atgattttca gtttctctgc catctccaac tattttatag
     6601 tttacttctt ctgtcttatt atcttgttta ttgtcgatct tgtcattcat ttgtctatta
     6661 tctttacttg agttaaactc tccgttcttc tggttactat caattacatt atttgaatta
     6721 gattgttttt cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca
     6781 attttgtaaa gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca
     6841 ggttctttcc catttgcatt agatttgatg aatgatatat acttactgga taaattataa
     6901 aattggttat ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta
     6961 ccaccgaata tactattctc tgagactact aaattatcac taactcgtaa taattcaata
     7021 tttggttgtt ctgtttcctt agaattatta ttaattacat tttttgttac agtaatatct
     7081 gatacttttc ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga
     7141 tcggcaatat taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct
     7201 ttagtgtttt tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca
     7261 ctctctcctt taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct
     7321 gtaaaacgta cacctgcata catcatgtta tcaaaatgat tatttaaaat tttaatatta
     7381 gaggggttct gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca
     7441 gatttatcac ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca
     7501 tcatcattca aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc
     7561 ttacttatga tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa
     7621 ttatcaacta atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc
     7681 ttgaatgtta cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa
     7741 gaatttataa gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata
     7801 tcaatcgtac caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca
     7861 tcatccgtaa ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca
     7921 tttagaattg tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt
     7981 tcttttacta aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct
     8041 gcagcatcta ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca
     8101 ccataatctt ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt
     8161 ataacatctt ccttataact cttattttca ttagtagatg ttactgtaga ttcaactgtt
     8221 ctgttgtcta attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt
     8281 aacgaattat ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattc
     8341 tgattaacag ttggtgaatt atctaaatca ttagtaattg cattagaaga ctcttttgta
     8401 gccatcggtg aagaactagt aacaacttca tccgctaaaa taccttggct tcccaaaatt
     8461 gaaattgcca atagtaccga gcaagtcccc acccttaatt tacgaatact gaatacctca
     8521 ttaggaacaa aatatttcat cagaacctcc aattttttta ctatttttta acaattgatt
     8581 attacttttc ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc
     8641 caaattgaat tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc
     8701 tcttcaaact aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct
     8761 atagtatact gaaactaaaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     8821 tgactgtccc gatcaatttg tcctattctt atttcatttt actatatcta caacctcaaa
     8881 gcagggtttt gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa
     8941 agtgatgcta tctttcttag cttgaatata aaatatccca tttactatat ttaaatttat
     9001 tgatatgttg taaattataa atgaaagaac aaataccttg tcatacaagc attcgccagg
     9061 gatatttacc tgaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc
     9121 ttaaatagac cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct
     9181 aaaatactgg aatagggcat ataggtaatc gtagacaagt gttttataga ttgtctcgca
     9241 ggagatctaa tgatgtatag caagcatcac taaacatata gaatatttgt attattataa
     9301 tatcaacata ctataaattc tatcatgcaa aagaatgact agaacatgaa agacaggcac
     9361 aaaactttga acaatattct gaaaacaaaa aaagacgcga gtttccacaa tctcactcat
     9421 ggaaactcac gtctttcaaa aaatagggtg aattgaaaac tagaacaaga cactagattt
     9481 tctaaatgat gtctagtaag gattctaaat gctacaccaa attgctcaca tcttatttca
     9541 aaccacggga ctcccacaag aaaggaaaat cctataaaaa ttctctctct gaggagaaag
     9601 gagcctcaac tacaggtgta aactattatc aattgaaaac aacagttttt acactcaatt
     9661 agacttttta aggacaggat cactttcgct tgactgtagt ttgtcatttt tttgataaag
     9721 ttagcacttt ttcagaaact gttttgaaag tctcaatgat atagtctact tcttcatcgc
     9781 ttaatttagt atgaagaggg agggtaattt cattctcaaa gaaggcatag gccttaggat
     9841 agttcgtcat atcaaatcca agattcttat aggctgtcaa gagaggaagc ggtttgtagt
     9901 gaacattact tgcaattcct gctttagcca attcttggat gatgaggttg cgttcttcta
     9961 ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga agattcgaca gtttcagtct
    10021 tgtgtgccaa aggatggatg cgagaacctg caaaaccact atcatagcgg tccacaatgt
    10081 ccttacggcg ttgcaacaaa cttggatagc ggtccaattg taccaaacca agtgaagcca
    10141 tgatatcggt catgttgcac ttataggctg gtgtaacgat atcgtattcc catgacccca
    10201 attgcatctt ggcaagagca tccttagttt gcccgtgaag ggaaaggatt tggaattcct
    10261 tgtacatctc ttcgtcatca atcactggat tggctttcca agtcgcactt ccaccttctg
    10321 ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt aaagtcagcg atagaaccag
    10381 aaggttgtcc tttataagta gatcccaaag cgtgggcact atcagagaca atgacaatac
    10441 ggttaaaggc cttttgccac ttgcttgaag cggtaaagaa gtcacgtttt ttctccacga
    10501 cttggaacaa acggtcataa tcgcaaacaa tccctgcgag ctctactggg ataatcacct
    10561 tagttttctc agtgatagct tgctcaagca ggtcatagtc catctcaaac gtatctgctt
    10621 ggatatccac catgacaggg gttgctccca cgtgcgtaat gacactacat gaagccgtat
    10681 aggtcatggc tggaacgatg acttcatcac caggtcccac ttccaaaacg cgtaaaatca
    10741 actccagagc agctgtcgca gagttgagac aaacagtctt aggtgtctgt gtgtaaagat
    10801 acaagcggcg ctccagttct tttgttttag gacctgttgt gatccaacca gaacgcaggg
    10861 tatccgctac ttcagcaatt tctgcttctg tgatatcagg cggtgaaaat ggaatattgt
    10921 aatttggcat tgatttgctc cttttatctg tactcatttt cttatgacta ctttatttta
    10981 gtacctcaaa cacggtttga aacatgattt tgatgtcccc aaagaaacta aactctcgga
    11041 gataggcgag gttatagcgc atcttttcag gaagaacatg ctccacatag gcctgatcaa
    11101 ctgacagacc tttctccgtc atttgactga tgatggtgtc ctcatccttg tagttgatgc
    11161 tggctggaga ggtaattcct gcttgcaaga gcaaggttgc catcatttca gggctatact
    11221 gctctgtata acgtggcact tcaggtcgtg taccgacaaa ggacatctca cctttaagga
    11281 cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg gatgaaattt ccaaccttgg
    11341 taatacggct atcgttagca gaagtcacca gacttccttt tttatccgca tccgtcacca
    11401 tggtacgaaa cttccaaatc ttgaaccgac ggttgtactg ggtcacacgc tcttgcttgt
    11461 aaatcactgg ccccttgcta tccaacttga tccaaatgct caagatgaga aagatgggag
    11521 aggtcagaac cagtaagatc aaggccaaaa cccagtccaa gcaacgcttg aaaatcagcg
    11581 aacccttcct tttagagaca agctggtagt aagactcaac ctcgcttgat ttcatttcca
    11641 caggcaagtc ttcccatttc agcatgctgt tctcctttgt ttttattata ctatttgtca
    11701 acatttttca ttataccaca aaatggaaaa ggcggtgaaa gaaatctgta atttgaagga
    11761 tttccttcta gtactcaatg aaaatcaaag tacagctttg agattgcaga taaagctgac
    11821 atggtttaaa gagattttca aagagtatcg gccatggccc ctgcctgcaa actatacatc
    11881 ttgtgataag ttcctcccag agccaagagt tcctcatggg ttccactctc gataatgcgt
    11941 cccttatcca agacatagat gcagttggcg tcttgaatag tagaaaggcg gtgagcgata
    12001 gcaatagttg ttcggccctg tctcatcttc gccagagaag cttgaaccaa actttctgtt
    12061 tcagagtcaa tattggctgt cgcttcatcc aaaatcagga ttttaggctg gctggcgact
    12121 gttctagcaa aggcaagaag ctggcgctgc ccagtagaga agctcgaacc acgctcggaa
    12181 acaggggagt cgtacccctg aggaagttct tgaataaagg aatctgcatc cacaaaggct
    12241 gccgcagcct gaacctgctc atcactgatt tcttggtaca tggcgatatt ggacttaata
    12301 gttccatgat agaggaaggg ttcctgcaag accaaaccga tgttttttct cagctcttct
    12361 tgactgaaat ccctgatatc cacatcatcc aagagaactc tccctgactg gaattcataa
    12421 aagcgcatga ggacattgat aatagacgat ttccctgaac ctgtatgacc tacaaaggca
    12481 atggtttcac ccttattaac agagaaagaa atgtcatcca gaatcggatg tttaccgtca
    12541 tatgagaaac acacatgttc aaaacggata ttgccttctt ggactttagc ctgcccattt
    12601 tcttgaaggg gctcataggt cctctcgtct atcagggcaa agacacgacc tgcagaaacc
    12661 atagccgttt gcagagttga aaagttttgc gtcacctcaa tcaaggggtc aaaaaggcgg
    12721 ttgatgtact ggataaaggc atacatggtc ccgaccgtta tcccgataga aaaaccacgg
    12781 tagccaaagt aggccatcaa gactgcatag cctagaagtt tcagcaaact catggcaggt
    12841 ctcaaaaaga gggcatccaa ggctacagaa cggttggcgt agaccaagtg ttcttggttg
    12901 atttcatcaa attctgcctg caggcgcttc tcttgattaa aggcctgaat aatcctgatt
    12961 ccctcgatat tctctgccag cttactattg atatctgaca agagacttct ggttttctcg
    13021 atgattttca ctgacttttt tcgatagaga ttgaccaaaa ggaaaatcaa aggaagaaag
    13081 agcaagacta aagccgtcaa acgaaaatcc agcaccaaca tggtataaag ggttgtcaga
    13141 aagataaaaa ctgctgagat aaagctggat aaaatcccag aaaacatatc actaatcgtc
    13201 tcggtatcgt tggtcaaacg agaaacgata gaacctgctg gcgtcttgtc aaagtaagac
    13261 atgcccagtt tctccatatt gacaaaggca tctcgacgaa tatccctaac aatactgtaa
    13321 gacacgcgcg caaagagaag attgccgaca tactgaacta cagtttgtag gatgtagaga
    13381 ccatagtaga ccagcaaaac ggtaacggct agttggttaa gattgctgag atactggtcg
    13441 ataaagtggg aagccacgag gggtatgaca cttttaatga ccgtcgtcgc taggagaaaa
    13501 ctgagtgcca aaaaggtcag gagtccataa ggcttgagat aagacatcaa gcgcttcaat
    13561 acagcccatt gttcttgttt attctgcatc ttcttctcct ttcatttcca actgctgaga
    13621 ctggtaggtt tgggcatacc agccatccaa agctagcaag tcttcgtgcc tgcctcgttc
    13681 gataatttga ccattttgca ggactaaaat caaatctgca tggacaacag cactgaggcg
    13741 atgggcagtg ataatggttg tcttgtcctt tcgcgtctcc ttgaggttgt cgataatcgc
    13801 atactctgtc ttggcatcta cggcggataa ggaatcatcc aaaatcaaga tatcagggtc
    13861 taaaatcata gcccgactca tagccaaccg ttgcttttga ccaccagaaa gactgactcc
    13921 tttttcacca atcagcgtat caaatccttg aggcatgtct acaatatctt ggtaaactcg
    13981 ggctagctta gtagcttcct cgaccgctga aaggggcaag ttaggattgc caaagcggat
    14041 attgtctagg attgaagtcg caaaaagaaa ctggtcctga ggaacatagc ccatgagact
    14101 gcgaaggtct gtcagacgat agtcccgaat atcgtgaccg tttagataaa tggcaccctt
    14161 atccacatcg tattcacgca agaggagctt gattaaggac gttttcccag agcctgtctg
    14221 cccaaccaag cccagtgttt gcccttttgc caaactaaag tgaatatccg tcagtgtttc
    14281 ctcattttca aaagcaaagc tgtcaatggc atactccaaa cgcccatttt caataccatc
    14341 cagaggaaac tcagggtctt gtacaggaga ttcctgagac aaaagatttt caatccgctg
    14401 gtaagaaacc ttccctcgct gagtagtatt aaagaggaag ccgatggcca taagaggcca
    14461 gaccagcata tccaaatagc tgataaaggt gactagattc ccaactgtaa tctgcccttc
    14521 ctgaaccatc aaggagccaa ccaaaagcgt taaaacatag gacgaaccaa caaacaagag
    14581 aaccataggg tcaaagagac tatcatattt catggtttgc aggttctttt ggaaggttaa
    14641 ttcattgact gcctgaaaag acttcaactc gtctgcctga taaccgaaag acttggttac
    14701 tttgatacct gatacggact cctgtacctt gttattgagt tcagaaaaag cagcttggga
    14761 ttcgccaaag gccttatgag tctttctccc taggcgacta gtcgtatagg ccatgaaagg
    14821 tagggggaga atggcaacaa gagtcatctg ccatgagatg ctaaagagca tggtcaacaa
    14881 agtcaccaga gccgtgatag aggcatccac cgcagacatg acaccgccac ctgctaaacg
    14941 agtcaaggaa ttgatatcat tggttgcgtg tgccatcaga tcacccgtcc gataggtttg
    15001 ataaaaggct gacgacattt ttgtgaaatg cttaaacaag cgagaccgca tgatctgtcc
    15061 caagcaataa gaggtcccaa ggatatacat acgccacaca tagcgcaaat agtacatacc
    15121 aaaggctgca agtagcaagt aaaataggct aagaaggagg tcctgctggg ttaattgccc
    15181 cgatgtgatg gcatcaataa cccgccccat aaccatagga ggaatgagat tgaggacgga
    15241 aaccaagacc agggccacaa tcccgactag ataacggcgt ttttctaact tgaaaaacca
    15301 ccaaaatttt tgaataatgg acataaaatc cctttctgat tgcaaataga aacctgaggc
    15361 caatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaggctg ctcaaagcac
    15421 tgctttgagg ttgtagatag aactgacgaa gtcagtaacc tacatacggc aaggcgacgt
    15481 tgacgcggtt tgaagagatt ttcgaagagt acaagacccc aggtttttct tatttataag
    15541 ttacgactgt aacagcaccc ttgtcatatt cagcaataaa gatattggct acattgtcat
    15601 gcccttgttt actgaggtta tcaagcaacc actcttcgct acgaccaatc gattccaaga
    15661 catctacttg aatcacaccg tcagtcacaa ctggatactt aggattttca tctcccattt
    15721 gcacaacgat gagttgccca ttttgctctt gcacagctcg tttgacttgc ttcatctgga
    15781 aaatcccttg gctacgaagt ttgagggcta catccgatgc agacaaacca actgaacgac
    15841 aggcttctgg gtcaatattc ccatttttga taaggaaagt tggcttacca tcaatcaaac
    15901 gtttcacaaa gtgaacattg ttgttgagct atttgagagt caagaccagt ttgattaaaa
    15961 tttcgatata attaagtgtc atttgttcac atccaccagt tcaattgcgt ctgtcttata
    16021 caattcgact ttctctaaca ggtacttgtc tggctcactt ccgtttaggg cacgataata
    16081 gcgatctccc accttgataa gtgcgccatc tgtgtttgtg gaagtattaa catagacttc
    16141 tgacttgtct actcccaaat ctttggaaac aacctcgatg aaatgaagtg aagtttgaaa
    16201 tttattgtta gaaacttgat tgttttgata agtcgtgatg ctgaccaaaa gcagagctaa
    16261 ataaggccag agctgaaatc atgaccaact cacgaaattt ggttcctttt ttatcatggt
    16321 atgccttgaa agcaaaaaaa actgtcacag ctaatagaac aatcccaaag ccaaccatga
    16381 taccattttg ctgaccgatt tggctgagta catagtcata agagtagaat ttcatgtatt
    16441 ttcactccct ttcataaaat cattcttaat tataaacgaa agagagtaat ttttcaaacc
    16501 atacgttggg gaaatagatc tttttttggt ataataaaat ctataatctg aatgaaaaag
    16561 gtaactttat gaaacttatc tcatggaata ttgattccct aaacgctgcc ctaactagtg
    16621 actcagctcg tgccaaattg tcccaagaag tcctacaaac cttggtcgct gaaaatgctg
    16681 atatcattgc tatccaagaa accaagcttt ctgccaaagg acctacaaag aaacacgtgg
    16741 aaattttaga agaactcttc ccaggctacg aaaacacgtg gcgctcttcc caagagcctg
    16801 cccgtaaagg ctatgctgga accatgttcc tttataagaa agaacttaca cccactgtca
    16861 ctttcccaga aatcggtgcc ccttctacca tggacttgga aggccgcatc atcactctag
    16921 aatttgatgc atttttcgtg acccaagttt acacaccaaa tgctggcgat ggtcttaaac
    16981 gcttggaaga acgccaagtc tgggatgtca aatatgcgga gtatttggct gaactagaca
    17041 aagaaaaacc agtccttgcg accggtgact acaacgtagc ccacaatgaa atcgaccttg
    17101 caaatcctgc tagcaaccgc cgttcacctg gatttactga cgaggaacgt gctggattta
    17161 ccaacctatt ggcaactgga tttactgata ccttccgcca tgttcatggc gatgttcctg
    17221 aacgctacac ttggtgggca caacgcagca aaacttctaa aatcaacaat acaggctgga
    17281 gaatcgacta ctggctcaca agtaaccgta tcgctgacaa ggtcactaaa tctgatatga
    17341 ttgactcagg tgctcgccaa gaccatacac cgattgtctt ggaaattgac ttgtaaggat
    17401 tttctatatg gactacaatg cggtcattcc cgagtttctt gtatcgaata tcgaacagtc
    17461 ccggtccttc tactgtggtt tactgggttt taggattgaa taccaacgtc cagaagaaaa
    17521 ctttctcttt ctcttgaaga gtgtcaacta atgttagagg agggaacaaa ggatcaacta
    17581 gctgaactga cctacccctt tggtcgtgga gtcaatctct cctttggcat aaaggatgtt
    17641 tcaaaactct atcaaaaagt gatggaggca aactatccta tttatcgtcc cttgaccaaa
    17701 agaaagtttc gtgtcagtga tccctatatc tatcctcata aatttgcagt tttggatcca
    17761 gatggctatt ttttaagatt tagcgagtag aataataaaa attgggaaaa gtctttaaag
    17821 ttagaaaaag gcatattgtc aggtgtctaa aaacttgata gtatgccttt tatgatggaa
    17881 aaatcttcta atactcttcg aaaatctctt caagccacgt caacgtcgcc ttaccgtagg
    17941 tatatgatac tgactctgtc aattctatcc acaacctcaa aacagtgttt tgaggttgtg
    18001 gatagcttcc tagtttgctc tttgattttc atttagtata aatgttagtt tacaatggag
    18061 tttttgttca ccttctcttc tgtttgttcg ttttttaaac caaaacacta acaaaaatag
    18121 ttgatttcta aagttattta gtgtaaaata aaaacattgg ctcaagccta tttaaaattg
    18181 aatatcgttt tacttgttta tgtcgtgaat tggcacgacg tttctacaag gtgccggaac
    18241 acctaacaat aagtaagtca gcagtgagat atggccgttt ttgccatgtc tatttagggg
    18301 acttacttag agattaagta ggtctttttt gaatattttt aatatttccc ttaattagtg
    18361 cggacgggag gtgaaattat cctgtgaata atttcaggaa tccagggaat ttcatcccta
    18421 atttttgagc caaaagtctc aaaaatcccg tcatagacaa taacaagatt attgtctatg
    18481 ataccactac aacgggaaat atttgataag actcgcttcg ctcgtaatag ttttatcaaa
    18541 tatatagtat tagcaaaagg gatcactata gaaatattta aacaacaagt aaattaactt
    18601 ttagacttta ggaggtctta tgaaattatt agaagagcgc atcctcaagg atgggcatat
    18661 cttgggtgat aacatcctca aggtagattc ctttttaacc caccaagttg actttagctt
    18721 gatgcgagag attggtaagg tttttgcgga aaaatttgct gctactggca ttaccaaggt
    18781 cgtaaccatt gaagcgtcgg gtattgcccc agccgttttt acagctgaag ccttaaacgt
    18841 tcccatgatt ttcgccaaaa aagctaagaa catcaccatg aacgaaggca tcttaactgc
    18901 tcaagtctac tcctttacca agcaggtgac cagcactgtt tctatcgctg gaaaattcct
    18961 ctcaccagag gacaaggttt tgattatcga cgatttcctt gctaatggcc aagctgctaa
    19021 aggcttgatt caaatcatcg aacaggccgg tgccacagtc caagctatcg gtatcgtgat
    19081 tgagaaatcc ttccaagatg gtcgtgattt gcttgaaaaa gcaggctacc ctgtcctatc
    19141 acttgctcgc ttggatcgtt ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta
    19201 atgcaaactc aagaaaaaca ctcgcaagca gccgttctgg gcttgcagca cttactagcc
    19261 atgtactcag gatctatcct ggttcccatc atgattgcga cagcccttgg ctattcagct
    19321 gagcagttga cctacctgat ttctacagat atcttcatgt gtggggtggc aaccttcctc
    19381 caactccaac tcaacaaata ctttgggatt ggactcccag tcgttcttgg agttgcattc
    19441 cagtcggtcg ctcccttgat tatgattggg caaagccatg gtagtggcgc tatgtttggt
    19501 gcccttatcg catctgggat ttacgtggtt cttgtttcag gcatcttctc aaaaatagcc
    19561 aatctcttcc catctatcgt aacaggatct gttattacca cgattggttt aaccttgatc
    19621 cctgtcgcta ttggaaatat gggaaataac gttccagagc caactggtca aagtctcttg
    19681 cttgcagcta ttactgttct gattatcctc ttgatcaaca tctttaccaa aggatttatc
    19741 aagtctatct ctattttgat tggtctggtt gttggaactg ccattgctgc tactatgggc
    19801 ttggtggact tctctcctgt tgcggtagct ccacttgtcc atgtcccaat tccactctac
    19861 tttgggatgc caacctttga aatctcatct attgtcatga tgtgtattat cgcaacggtg
    19921 tctatggttg agtcaactgg tgtttatcta gccttgtctg atatcacaaa agatccaatc
    19981 gacagcacgc gccttcgcaa cggttaccgc gcagaaggtt tggccgtact tctcggagga
    20041 atctttaaca ccttccctta caccggattt tcacaaaacg ttggtttggt taaattgtca
    20101 ggcatcaaaa aacgcctgcc aatctactac gcagctggtt tcctggttct ccttggactg
    20161 cttcctaagt ttggcgccct tgcccaaatc attccaagct ccgtcctcgg tggtgccatg
    20221 ctggtaatgt ttggttttgt atcaattcaa gggatgcaaa tcctcgcccg tgttgacttt
    20281 gctaacaatg aacacaactt ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc
    20341 aacaacagta atctctttgt cagcatgccg acagccttcc aaatgttctt ctcaaacgga
    20401 atcgtcgtag ccagcctact cgctattgtc ctcaatgccg tattaaatca taaaaagaaa
    20461 taagaaaaag aggtgcgagc ctcttttttg ttgacaaaat aaaaacatct acctattcat
    20521 atatgctagt gtcatagtcc tgaaaatcat ctgcatcaag aacaatttca caactcttat
    20581 acttttctct tacaagtcgt tcggcttcat ctggattttc agcctctata cttactaaac
    20641 gtgataaagt ttctgtaatt tctactgtat actttttcag ttttagattg ctttccaata
    20701 attcacctat taacaataat ctatgatagg agctatgtag ccactctggc aatttatctc
    20761 ctacttccca cccatatttt tccttcatca aagctagttg tttttcgtca ccaaatttca
    20821 tattttcaga taaccatctc acacaatcgg gatctgataa ggtacagacg attaaactta
    20881 ggttatcgta acggctttca gtttcataat caggccagat gacttttaag aaatcataca
    20941 cctcttctga tgcaacaagt tgtttcgttt tcataatttc cgatactttc ctctaccttt
    21001 aaattctatt atttctttgt ctcttaatat ttgaagctgt tgcctaatct tttctttgat
    21061 atgattgttc ttaacaaaga tattttttag gtcactttca aaacgataca tatcttcaag
    21121 ggtaaattct gaaccctcta tcttatctat acaatttaga atttctattg tccaacctct
    21181 tgatgacaga gagctcttcc ttaaaaataa accttgctta aattcttttg taactttttc
    21241 tggatctcta acttgtccat cttgcacaag aaatatcctt cctttagaag gtacttgtga
    21301 taaatcaatg tcacaaccaa tccaacctgc tcgtctagca gttggtgcaa gtggttttct
    21361 ttgaataatc gatttcggtg taacaaattg cttcggaagg acaagaaagt tatttacctc
    21421 aaaatttttt gtgtaagtta aaaaaaagaa attaggatta ttatctgcct gcacacgctt
    21481 catcatcgtt gcataagcac catcattgat tgttgatgaa aaatttcctt ttttgctctt
    21541 tagttcaaac tcctcactac aatgattaca gtaaaaatct gctacaggcc gattattttc
    21601 aaaatgattt aagggattgt tcccacaatt agggcaataa gactgacgat aaacccaatc
    21661 ctccgttaag atacgtgcct tttggctatt acttttatag gtttctacta attctaaatt
    21721 aaaatgtaat tccatttaaa aattcctcac taatatgaga actcactcga tataagcaat
    21781 taaaatctac tataactagt ataccacata tatgtaccta ttacatttgt atttcatcac
    21841 tctcttttat atttccttct aacatatctc ataaattaaa aatgagtgag ataaatttat
    21901 cccactcacc tttctttata tacttacccg tctttcctca gacctttggc ctgtgacaaa
    21961 catggtaaag gttgctttac agacatttct gccctcttga ttggtgatat ccacatccat
    22021 cacacaggtt gtacgacctt gatggacaca ttctccttta atggtcaata catcgtcgag
    22081 ttttcctgcc ttaaggtagt tgatagagga ttggagtgtc accccatcaa gtcccagcga
    22141 gataaccacc aaaccactga tttggtcaca tagcgtgaat agatagccac catgggcatt
    22201 gccatagtag ttgagcgacg agttcactac tttggtcgtc accacaacgt gaccatctct
    22261 cattttttca atttcgtaat tttcaaaggc agatatagcg tcaaaatgaa agtctttcat
    22321 cgtttcctcc tgatatttca aacgacacta tgatactact ttttatagga ctgtgcaagg
    22381 agaaagctcc tagtctagta aaattccgac ctgttccaca aagcgcataa aggctgtctg
    22441 cccttgttct gtctgcttgt agactcctgc atcctcaagt acacgcacaa agatagcacc
    22501 cacagagtcc ttgacgattg caagggtttt ttctttatcc gttaggtctg gatgttggga
    22561 ttttagttgg tctgcccact cctgatgata atcggcaact gtaacagctt ctcctacaag
    22621 atagctagcg acttgctcca cttcttcttt cagacgtggt ggcaagattg ccaagcccat
    22681 gacctcaatc aagccgatat tttccttctt gatatgttgg acatccttgt ggggatgata
    22741 gatgccatca ggatgctctg ctgaagtctg attgtctcgc aagaccaagt ccaactcaaa
    22801 ctgtccatca cgcttacgcg ctattggtgt gatggtgtga tgcggtgtcc cgtctgtctc
    22861 tgccaaaatc tgcacactag aatctgaata ctgacgccat tcctggaaaa tcttatcagc
    22921 taagttaatc aaatcctctt tggaatccga agtcaagcgt aggacagaca ttggccactt
    22981 gataattcca gccttgacct gctcaaaacc agcaaatcgg aaggtctttt gcaagggagc
    23041 caattccata ggaaatacgt gacggcctcc ctgataatga tcatgagtta gaatagagcc
    23101 ccccacaatc ggcaggtcgg cattagatcc agcaaaatat cctggaaact gctctacgat
    23161 agccaacaga cgttcaaaac tctgacgact aatggccatg ggacgatgct ggccatctaa
    23221 aaagatacaa tgctcattaa agtaagcata gggcgaatac tggaaacccc attcctgacc
    23281 aaccatttca aaacggataa tccggtggtt ggtgcgagct gggtggttga cccgaccatg
    23341 gtaaccctca ttctctaaac aaagttgaca ctgaggataa ttactagctt gcaccaactt
    23401 ggctgccgca atctctttcg gatccttttc aggcttagag agattgatgg taatttcaag
    23461 ttctccataa tcagatggaa cacgataagc gatattttta gcaatggcct tgagtttgat
    23521 gtagtcattt ttctgactga gttgataaaa atcctctatc gcttgctcag gagagtggac
    23581 ataggcttcc cagaagtcac gattgacctg actcggacaa ggagtcacca agtccatcaa
    23641 ttcagtacca aggatttcac gcgcagtctg actatcctca atcgtctcta atcgaacggc
    23701 ttcctcaact agctggtcct tgaggtcaat caatttatcc agattggtct caacttccaa
    23761 aacaccttct cccactcgtg ccaaaacacg attggtcagg tagattcgat ccatttcctc
    23821 aaatgaactt tcagaaatga catgtgttac aaatttatct actaaggtca ctatagagcc
    23881 tccttttgac tagtcaagga cgcgagtgcc acctgcaact tcagcgatat agaagcttgg
    23941 agcgtatcca actacttcct tgtagtgttt gcctacagct tccttaaagg cctcaacagt
    24001 atctttttga accaaggcaa tggcacagcc accaaaacca gcccctgtca tacgagcacc
    24061 gagaactcct tcttgtgccc aagctgtgtg aacaagagta tccaattcca aaccagttac
    24121 ttcataatca cgctccagag aaacgtgtga cgcattcatc aaacgaccaa atgtttccaa
    24181 atcacctgct tgaagggctg cttgagcttt aagggtacgt tggttttcaa gcacagcatg
    24241 gcgagcacgt ttcaaacgat tttcatcttt aatcagatag ctatattggt caacggccca
    24301 ctcgtccaat tcacccaggg tctgaatatc caaggcaact tgcaattctt ccactgcttt
    24361 ttcacactca gcacgacgtt cattgtattt agagtccgcc aattcacggc gtttgttggt
    24421 gttcatgata acaacgacat tgtccttcaa atcaagtggc accaagtcgt attctaaagt
    24481 attggtatct aagtaaatag cacgttggtc agcccccata ccaatagcaa attggtccat
    24541 aatgccagaa tttactccga taaagttatt ttctgtttgt tttccgattt taaccaaatc
    24601 gagacgctct agttttaaat caaagagatg ctctgccaca actcctgtca agagctccaa
    24661 ggatgctgaa gaagacaaac cagcaccatt tgggatattc ccataaacat aaaaatcaaa
    24721 acctttgtca atcacgtgcc cagcttcttg caagaaatga aggacacctt ttggataatt
    24781 ggtccagttg tgctcttttt caaacttgag gtcagcgaga ggcacttcga taatgccctt
    24841 gtcctcaaag ttagctgagt agaaacgcaa gacttggtcg tcacgcttac gagctgcacc
    24901 gtaagttccc aaggaaatag cagcaggaaa aacgtgccca ccgttgtagt ctgtatgttc
    24961 accaatcaaa ttaatgcggc ctggtgaaaa gaaggtttgg tctgcttctt gaccaaaaac
    25021 agcaagaaag tctttgcgaa gggcttcagt agtaagatgt tgtgccatat gaattctcct
    25081 ttgactgtcc gttaagccat cttaacgtgt aatcgttttc tttctattgt atccaaggaa
    25141 ttttccaagg tcaatccttt ttactaaaat tttagtaaaa tatcagtaaa aagaagaaaa
    25201 acatgatata ctaacctaat caaggaggat ttatggctac cttaaaagac attgcacagc
    25261 tagcctctgt ctctatcgcg accgtatccc gcgtcctcaa tcgcgaccag agcctatctg
    25321 ttacagaaga aaccagacac cgtattttaa ccgttgctga agagctgggc tacaccaagc
    25381 acctcaagac aggcgagtcc cacaaaccca agcaaaagat tgccattatc caatgggtca
    25441 gcgaacaagg ggagctggac gacctctact actaccagat tcgcctagga atagaaaaaa
    25501 gagcccaaga gttggactat gatatcttgc gctattttaa tgaccaccct tttaccctaa
    25561 gcgaggaagt gattgggatt ctctgcatcg gaaagtttag tcgagctcag atttctgcct
    25621 ttgaagaata ccaaaagcct cttgtatttc tagacagcga tacactttcc ctgggacata
    25681 cctgtattat cacggatttt tacactgcta tgaaacaggt tgtcgattat ttcctcagtc
    25741 aaggaatgga ccgtatcggg attctaacag gccttgaaga aacaacagac caagaagaaa
    25801 tcattcagga caagcgtcta gaaaacttca aaaactacag tcaagcgagg ggaatctatc
    25861 atgatgaact ggtctttcaa ggaagattta ctgcccagtc tggctatgac ttaatgaagg
    25921 aggccattca gagcttggga gaccaacttc cgccagcatt tttcgcagcc agcgatagtt
    25981 tagctatcgg tgccctccgt gccctccaag aagctggaat cagcctgcca gatcgcgtca
    26041 gcctcatttc ctttaacgac actagtctga ccaaacaggt ctatcctccc ctctctagta
    26101 ttacagttta tactgaagaa atgggccgag caggtatgga tattcttaac aaggaagtcc
    26161 tccacggtcg gaaaatccct agcctgacca tgctgggaac cagactgaca ttaagagaaa
    26221 gtaccctaaa tcaagaatag gataacataa aaaacgaata gagttctaaa actcctattc
    26281 gttttttatt cgattacaat catagactta atggtcttac gttcatccat atctttgtag
    26341 gcttggtcga tatcttccag tttataactt gaagtaaaga cgcgacctgg attgatatca
    26401 ccatcaagga cggcttttag taaaaattgc ttatcgtatg ttgtagcaga agctgcccca
    26461 cctgctacag agatattttg cataaatgtc gaaccaagag cacgattatt atagtgtggg
    26521 actcctacaa agcccatacg ccctccatta tgaagaacac ctagcgcctg ttctatagca
    26581 gcctccgtac caacacattc aagtgctgcg tctgctcctc cgccgaggat ttcacgcacc
    26641 ttggtaattc cttcttgacc acgttctgca acaacagctg tcgcacctga ctccatagcc
    26701 atcttttgac ggtcttcatg acggctcata aggataattt gtgatgctcc acgcatctta
    26761 gccgcgatga cagcacattg accaacagcc ccatcaccga taacaacaac cttgtcccct
    26821 ttttgaacat ttgcaacacg cgccgcatga tagcctgtcg gcatgacatc tgcaagagtc
    26881 aaaagggact tgagcatccc ttctgtatag tcagaaggtt gaccagggat tttaaccagc
    26941 gcccagtttg catagtggaa gcgaatatat tctgcctgaa aatcaccccc caaattattg
    27001 ccaatatgat tgtcgcaaga accgtcaaat ccagcaagac aggcatcaca ctcaccacat
    27061 ccatgtgtaa aagggacaat cacaaaatca cctggtttca ccgtcgtaat ggcttcccca
    27121 gcttcttcaa caatcccaat cgcttcgtgt ccactatttt tgtgtccaac tttcgtttct
    27181 ggattacggt acctccataa atctgaacca caaacgcacg cacgaaccac acgaataatc
    27241 acatcatccg cttctattat ttgcggacgt tcaatgctag caagtccaac ctgacctgcc
    27301 tttgtatata ctgctgattt catttaaaat tttccttcct tataaagttt aattttgaga
    27361 tttaaacgat ttaaagctgt ctgtatctga gacaagcgct cctctaattt ttgcttttcc
    27421 tcttctaaaa taccaagcct ctcctctctc gtttcatctc ccttttggta gagcgacata
    27481 tagtcaacta aactatctac agagacaccc gccgaacgaa aacacttaat aaattccagc
    27541 gcttcgatat cctgatcttg aaaatcacga atcccagtag cagtacgagt aatcggtggc
    27601 acaagaccaa cccgttcata ataccgaatc gtatccgctg aaatttccaa caaatcactg
    27661 gcagatttaa tattcacacg ctaacctcct ctcatttcat tcactgagtt cacgctattc
    27721 taactcactt atcttattat ataactttga gttgactcca agtcaagcat tttgtatcta
    27781 atcgaaaaat ttttatcatt aacaatcata tatctggagt ttatacaatg ctcttctctt
    27841 accaattttt gaaatattta aataataaag aaattactct attccaaata agatagtacc
    27901 caagtatttt tcactttttt ctaatgttga tgctcataac tccgttccaa gtcacacacc
    27961 tttcgcttat gggtttgatg agtttctagg tcagcatcaa tttcaatggt aatattttga
    28021 aaaccacaat cttttaggaa aattcgaata gactctttac aagtttccat atgttccatt
    28081 tcttttagac aaacatggac aatggcattt ttttccaaag catccatagt ccagagatta
    28141 agctgattaa ggctggccac attgtccaat cgttccaggc cactctttac ttgcttgata
    28201 tcaagacctt ctggcacagc atccaagaaa atcttgagtg tagaccaaaa acgtgaaagg
    28261 gcttttgaaa gaataaagaa agaaatgaca agggacaaaa gaggatctag gatataccag
    28321 tccgtaaatc gaagaacaat cgccatcagg ataacagcta cccaccctag cgtatcttcc
    28381 agaaaatgca gactcagaat agactcattc tttgtctttc ccttaccaac caccagactc
    28441 gctaacagat tgatagtaat cgcaataatt cctaaccaga gaatcccctc atcattgact
    28501 ggttgcggat gcaaaatctt cgtgacattt tccaaaatga ctagaacaga gcctgttacg
    28561 agaatcacag ctgttaccaa ggctcctagc aggctaaatc gcttatagcc caaggtgtac
    28621 tgattgtctt cttcacgatt ggagattgtt tctagaaaag ctgatattcc aattgcaatc
    28681 gcatctccca agtcatgcac agagtcagca agaacagcgc tagaaccaaa tactccacct
    28741 gcaataaact caacaatggc ataagtcaaa tttaagaaaa aagccaccca aacagcatat
    28801 tttgccttca tatttctcat tcctttgtta taatagattt atgaacacct tgttcattat
    28861 cattatccac taaaactcaa agaaaggata gaagcaaaac gtcagcttta ttcagttctg
    28921 aacaatttgc cttaagtgtc catatgacta acattgaccg ccgtatcagc aaaaccaaaa
    28981 aagccatcta tcaagctttt atacaacttt tgaatgctaa gggctacgag gccactactg
    29041 ttcaggatat cattgatctc gcagatgtgg gacgatccac cttttactgt cactatgaga
    29101 gtaaggagct tcttctggac cagctctgcc gctacctctt ccatcatctt tttgaaagag
    29161 agcaagccat ttcaaccgag gactacctcg cccacctctt tctccatttt cataaaaacc
    29221 aagaccatat caccagtctg ctattttcca aaaatgacta cttcctccgt caactccata
    29281 aagagctaga acaccatgtc tattccgtgc tagctgataa tttaaaagaa gcccacccta
    29341 atctgcctac ttcttacctc caacacttgg tcgtgtccaa ctttatcgag acattgacct
    29401 ggtggctcaa aaaaggtcaa gatttcacag accaggaagt tgtccaattt tatctagacc
    29461 ttctcattcc taaaaattga atatagagta aagcttcagt tgtcttattt ctaggttact
    29521 gagtttttta tcttttcaac aacaaaagag gacccgccga tcctcttttt catactataa
    29581 atccttgatt atcaactata tctgttttaa tcgaaatctc aaaacagcac tttcaaacat
    29641 cttttcctag ttaagtaaat cagtattttg cttagctgcc ttgctccatt gataccaacc
    29701 aactagactg ttaatgagat aaattagata tttcccttga atttgcaggc tttctcccca
    29761 ccagagatag attgaaaaga cattggtagc cgcccagaat atccactgtt cacggtaaac
    29821 agctgtcatg aggatttgcc ctaccccatt ggttgcatct gtgattgaat cacgataggg
    29881 acgattggca ccaatagact gataaatgaa gccaaaggcc aaccaccaaa gcacactaat
    29941 ggaaagatac tttgtccagc ccttgccgtc cagtttacgc gcgacaaact cctgcttttc
    30001 cttcttaaac tgtgcctgat aaatccaaac tagaagtcca attggctgca tgactgtgaa
    30061 gtaaagtgtc gtcagcacct caccataaaa gcctttctgt agggccaaaa taaggtaaat
    30121 aacagagtta atcaagccaa aaagataatt acttgctcga ccttccgata caaagattac
    30181 acagataatc cctgtcaagc tacaaatcat cccaatccag tcaacaatac gatgttcgta
    30241 aaccaactcc agccagagag gaaaacttcc taaaaccagc aaataaatcc actgggcaaa
    30301 actacgatgg gcaaagaggt catcccagat agccttcata gttcctgaaa atcctaaatc
    30361 agccatagcc gcaaccatac gacggtaacc acctgacatt tcacctaggg ttgttttgat
    30421 attttcaatt ttcttttgca aataagtatg catcatttct ccttttgttt ttaaagagcc
    30481 gtgtctggat agactttcgg acgcaacgct ctattagata atgaactgcc tatacacaag
    30541 atttctaacc ttagtcgaca tgagctgaaa cctcttattt gttaagtagt tcacaaaata
    30601 ttatacacct attttatgaa tagtcaactg tctttacagt aaaattttag aaaatcatga
    30661 aaattttctc tttctttcca ttttaagtga cattcagtca ttctcacatc aaaaaagccc
    30721 agacgaaatt gtctgagcat tcttttatct agtcgtttaa ggaagttgag ttcagtatgt
    30781 ttaaagtctc tgtcccatca tttcttcaac aaaccttgtt cttggagaaa ctccttggct
    30841 acttgctctg ctgacttgcc ttcaacaccg acttggtagt tgagctggct catctggttt
    30901 tctgtaatct taccagccaa tgtattaaga actctttcca actctggatg tttcttgaga
    30961 agagcttctt tcatgagtgg agccccttga taaggtggga agagttgctt gtcatcttcc
    31021 aagacctgta aatcataacg ctccaattcc gcatcagtcg aataggcatc cgtgatttga
    31081 atatcccctg actgaattgc ctgataacga agagctggct gcatagtcgc cacattgaga
    31141 ttgagaccat acattgattg caagccctta tttccatctt cacggtcgtt aaactcaagc
    31201 gtaaagcctg ccttcagctg cccttccact tttttcaaat ccgaaatggt cttcaagcca
    31261 tattcttgag caatcttttt cggaacagct acagcatagg tattttgata agacataggt
    31321 ttgagatagg ctagatgatc ctgcttggca atgccatcac gcgccacttg ataaacctgc
    31381 tctggctcat gactcacctt gggtgatggt tgaagcaaac tttcagtcac cgtaccggta
    31441 aattcaggat aaatgtcaat atcacctttt ttcagagctt cataaaggaa acttgtcgtc
    31501 ccaaaattcg gtttaacagt cgcagtcatg ctggtatttt cttcaatcag caatttatac
    31561 atattagcca aaatttctgg ttctgggcct attttcccag caataatcaa gttttccttc
    31621 tctttttgag ccaaaagggc tggactataa gacagaccca gtaataaagc caccaaggca
    31681 aaaccagaga aaatcgtccg caatttcgct ttttccatta cttttagtag gaagttaaag
    31741 gcaatagcta gcactgcaga agaaagtgcc ccaatcaaaa tcagactggc attattacgg
    31801 tcaattccca aaaggataaa ggaacctagt ccccctgccc caatcaaggt cgccaaggta
    31861 gccgtaccga taatcaagac cgctgccgtc cgaatcccag acatgataac aggcatggca
    31921 agtggaattt caaacttctt gagacgctcc catctggtca tcccaaaggc aatcccagcc
    31981 tcttgcagac tcggatcaat tcccttcagc ccagtaatag tattttgtaa aatagggaaa
    32041 atagcataaa tcactagagc tgtcaaagcc ggcaaggtcc caattcccat caaagggata
    32101 aagagcccca acaaggccag agacgggatg gtctggaaaa tccctgcaat ctgcaagacc
    32161 cagtcggcca gcttctcatg atagcgaaga aaaacagcca agggaatcgc aagcaaaata
    32221 gctagtaaca aggtcaaaag tgacaactgc aaatgttgag atagagctgt caaccaatca
    32281 ctaaaacgat cctgaaaagt tgcaattaaa ttagtcatga acactacctc caaacaagtc
    32341 tgctacaaag tctgttgcag gcacttttaa aattgtctcg ggattcgcta cctggcgaat
    32401 ttctccatcc tgcaagacag caatacggtc cgccaacttc aaggcttcat ccgtatcatg
    32461 ggttacaaaa atcgttgtca tcccaaactc tttatgcaat tcttttgtca gaacctgcaa
    32521 ctgttttctc gaaatagcat ccaaggccga aaagggttca tccatgagga aaatcttggg
    32581 ctgaccaatc atagctcgga caataccgac ccgttgctgt tctccaccag ataattcact
    32641 aggtaagcga tgcccatact cggctactgg taaaccaacc ttagccaaaa gctcttctgt
    32701 tttcttcgta atttcttcct tgctccaccc cttcatttca ggaatgagag caatattttc
    32761 cgcaactgtt agatttggaa aaagagcaat agcctgtaaa acataaccag tagaaagacg
    32821 aagttcacgc tcatcatagt ctttgatgcg cttcccatcc atataaatat ttccatcagt
    32881 tggttccaaa agacggttaa tcatcttgag catggtcgtc ttacctgacc cagaaggccc
    32941 tactaaaacc ataaattccc catcctcaat ctgtaagttg acatctctca agacatcctt
    33001 ttctgtgtag cgcagtgcta catttttgta ttcaatcatt ctttgtcctc aatttaaaac
    33061 ttccctcgat tggtcaagtc ttctacctta ggcatgactt ccttattatc ccaatgctcc
    33121 acaattttcc cgttctttaa acggaagata tcgtacttgg cataagcaac gccatcaatc
    33181 tgagtctgac catagctaac cacatagttt ccttgtccta agagttggaa aacaaagtca
    33241 aaagtgacac tatattcagc cacatagttt ttataagcag cacttccttg tccaatctca
    33301 tgattatgct gaatcaaatc gtctgccaca taatcactcc actgctctag ctccccattt
    33361 tggaaaattt ctgtcaagaa acggcgaacc agctttttat tttctgcttt cttgtccaaa
    33421 tccttgattt caaaatctcc aaaaatttga tctagttggt cattttcagg tgttcgatag
    33481 tagtcaatga catcccaatg ctcaacaata cgaccattct catccgcacg gaaagtatcc
    33541 gtcgtcaccc attgagcttc tccaccattc agatattgat gaacatgaac aaagaccaga
    33601 ttgccatcct caatggtgcg gacaatctta atctgacgct ctggatgacg ctcaaagaaa
    33661 tctgcaaaga aggctgcaaa tccttctttc ccgtcaggaa cacctgtcga atgttggata
    33721 taggtatccc ctacagactg ggcttgagcc ccagcaactc gtccgtcttg aatggcatgg
    33781 atgtataggt tgtgagcatt tttcacttgt tgtgacatat tctaaacctc atttcccttc
    33841 tctttcagat tcgccaaaat tctttcttga aaaccttcaa attggtgaat ttcttcctct
    33901 gaaaatcctt tgtaaaagat agtatccaat ttctgactga cacgatgccc cacttctttc
    33961 tgggacttgc ctaactccgt taaaactaaa tacttcttac gcttgtcttt tccacacgga
    34021 ctaacaatta caagcttttg ttcctctagc ttttttatca tagtcgtcag cgtattattc
    34081 gcaagcccag tcgcaagcgc gatatctgtc gcagttgcgc agccagtttc actattccat
    34141 aaaaccgcta aaatcttgcc ctgttcaccc ctataaagag cctcaggatc ttgactcagt
    34201 aacttttgaa aaatccgccc attcaacaaa cgaatatgat gggctagcaa atgactatct
    34261 ttcataacac ctccaattta tttcgatatc gaaatgaata aaataattgt aacactcatc
    34321 gttctaactg tcaactattt cgatttagaa ataatttttg ataattatcc acaccaccat
    34381 actccggctc aactaacttt taacgagagt ttctaaactc cttcgtcctc cagtctacaa
    34441 aagccttcca tccgtactat cctatatttt atgaggggac acatttttcc tatcagagca
    34501 tttattttaa agatagaagt aaatcataat tgcttccatc tgttctttta tagtatattg
    34561 aagttggact agggcactgt atcttctaaa acattgatag aaagcgattt gaatttccca
    34621 atcaatttgt tcgtctttat agcatttcga aactggaata ggacaccatg actgctaaaa
    34681 gatttctata aattcatttg atttccctaa tcaatttgtt catatcttat ttcattccgc
    34741 tataatttca ccttacccta tctttttcgt agcacccttc aaacagccta tcccctaccg
    34801 tttgacgatt cctcacttca ctccacttcc attacagaag tttcttcact actatggtct
    34861 cggctgactt ctcatgattc cttgttacta ctatttgaac gctcacgaga taggtcttat
    34921 aaaaaatgct ttgatccaca atggaatcaa agcattttaa aaagtccctc atacataagt
    34981 gcagaagtcg cagttcctct gtacttggct tcttctcttt tgataaagcg agccaagttg
    35041 agcaactcag gtgctggatg tttgggattt aggagcaatt cacgattgac caggcctgag
    35101 agacgaactg cctgcaattg ctcatttgta gtaggcagtt ttttagtagt ctctaggaga
    35161 gcagcaacta aatcttcact caaatcatgt cgagcatgat tgtaaagatc ttttataagg
    35221 ctttctaggt ttggttctgc catccctacc acctccctta tggtttaata atgtttaatc
    35281 aaatcaaccg ttgaacgatc caatttcttc accaaggctt gtaagaaagc ttgcgcttct
    35341 aggaagtcat ccattgcata gagggtttgg tgagaatgga tataacgagc gcagacaccg
    35401 atagttgttg atgggacacc accatttttc agatgagctg cacctgcatc tgttccgcct
    35461 ttaccacagt agtattggta cttgatacca gcttcttcag ccgttgtcaa aaggaaatcc
    35521 ttcatccctg ggagaagcaa gtgacctgga tcatagaaac gaatcaaggt tccatctcca
    35581 atcttgcctt gaccaccgta gacatcacct gctggtgagc aatcaactgc gaggaagact
    35641 tctgggtcaa acttggttgt agaggtatga gcgccacgca gaccaacttc ttcttggacg
    35701 ttagaaccca gatagagttc attgccgagt ttttgacctg ataaagcttc agctagctcg
    35761 cttaccatga ggacaccgta gcggttatcc caagcttttg agatgatatt tttttcattg
    35821 gctgtcaaaa ttgcagaact atctggtacg atggtatcac caggacggat gccaaaactt
    35881 tctgcctcag ccttgtccgc aaaaccacca tcaaaaacga tatcggcaat ggctggcatg
    35941 gttggtcccc cctttccacg agtcaaatgc ggaggaacag aacctgaaat cacaggaatt
    36001 tcatgaccat cacgagtcaa gagtttgaaa cgttggctgc taaccaccat ggggttccag
    36061 ccaccgattt ctacgacacg gaaggtacca tctggcttga tttcgctgac cataaaacca
    36121 acttcgtcca tatgagaagc gaccaagacg cgcggtgcat ccacagcttc tgaatgtttg
    36181 ataccaaaaa taccacccaa gccatctgtc accacttcat ccacatgcgg tgtcaacttt
    36241 tcacgaagat aagcacggac aggcgcttca tgacctgaga ctgcagcaag ttctgttact
    36301 tctttaattt ttgaaaataa tgttgtcatt tcagttcctt ctttctttca tccattttac
    36361 cactttttat aggagaagga tagtgggaag gtggatttct aagttagtat cttagtcctg
    36421 ctctatctta gaaaaggata gtattctctt gcatgtagtg caaaatctag taaacattcc
    36481 aaaattaact cgaatattta tttccaaaca aaaaacaata caccatcaaa gttgtttgga
    36541 tttttcatga aatttacaga aaatagttga cttccctttc ttctttcttt aaatatatag
    36601 ttggttgagt ttggaatagt acgctgtagc tgcta
//
LOCUS       DAVKBC010000017        34816 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVKBC010000017 DAVKBC010000000
VERSION     DAVKBC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34816
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.017"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(268..629)
                     /locus_tag="VWX64_000989"
                     /pseudo
     CDS             complement(268..629)
                     /locus_tag="VWX64_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
     gene            637..717
                     /locus_tag="VWX64_000990"
                     /pseudo
     CDS             637..717
                     /locus_tag="VWX64_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(1615..2304)
                     /gene="rplA"
                     /locus_tag="VWX64_000991"
     CDS             complement(1615..2304)
                     /gene="rplA"
                     /locus_tag="VWX64_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU9190474.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2512..2937)
                     /gene="rplK"
                     /locus_tag="VWX64_000992"
     CDS             complement(2512..2937)
                     /gene="rplK"
                     /locus_tag="VWX64_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU9190475.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            3069..3206
                     /locus_tag="VWX64_000993"
     CDS             3069..3206
                     /locus_tag="VWX64_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190476.1"
                     /translation="MKIKEQTRKLATGCSKYSFEVADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(3246..3962)
                     /locus_tag="VWX64_000994"
     CDS             complement(3246..3962)
                     /locus_tag="VWX64_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU9190477.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(4043..4827)
                     /locus_tag="VWX64_000995"
                     /pseudo
     CDS             complement(4043..4827)
                     /locus_tag="VWX64_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(4847..5276)
                     /locus_tag="VWX64_000996"
                     /pseudo
     CDS             complement(4847..5276)
                     /locus_tag="VWX64_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
     gene            complement(5278..6315)
                     /locus_tag="VWX64_000997"
     CDS             complement(5278..6315)
                     /locus_tag="VWX64_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU9190478.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDGQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFGFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(6413..7738)
                     /gene="brnQ"
                     /locus_tag="VWX64_000998"
     CDS             complement(6413..7738)
                     /gene="brnQ"
                     /locus_tag="VWX64_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU9190479.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGVIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(7909..8001)
                     /locus_tag="VWX64_000999"
     CDS             complement(7909..8001)
                     /locus_tag="VWX64_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9190480.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(8044..8178)
                     /locus_tag="VWX64_001000"
     CDS             complement(8044..8178)
                     /locus_tag="VWX64_001000"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9190481.1"
                     /translation="MKEIAFDAFYQLSLVDVREVDEFAALHLEGAHNLPLSQLADSYD
                     "
     gene            complement(8331..8915)
                     /locus_tag="VWX64_001001"
     CDS             complement(8331..8915)
                     /locus_tag="VWX64_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU9190482.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIYSQ"
     gene            complement(8969..10369)
                     /gene="pepV"
                     /locus_tag="VWX64_001002"
     CDS             complement(8969..10369)
                     /gene="pepV"
                     /locus_tag="VWX64_001002"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU9190483.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFDFAGPAKEYLDITGKILLNDHEGESLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(10382..10987)
                     /locus_tag="VWX64_001003"
     CDS             complement(10382..10987)
                     /locus_tag="VWX64_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU9190484.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            11158..11958
                     /locus_tag="VWX64_001004"
     CDS             11158..11958
                     /locus_tag="VWX64_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9190485.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKISVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(12140..12973)
                     /locus_tag="VWX64_001005"
     CDS             complement(12140..12973)
                     /locus_tag="VWX64_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU9190486.1"
                     /translation="MNHKIAILSDIHGNVTALEAVIADAKNQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLHFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQGHNLELLASLIEKHGYVEDVKDYFDF
                     L"
     gene            complement(12963..14807)
                     /gene="uvrC"
                     /locus_tag="VWX64_001006"
     CDS             complement(12963..14807)
                     /gene="uvrC"
                     /locus_tag="VWX64_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU9190487.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVIFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(14847..15548)
                     /locus_tag="VWX64_001007"
     CDS             complement(14847..15548)
                     /locus_tag="VWX64_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU9190488.1"
                     /translation="MRWLFRLIGAFFFFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(15627..16859)
                     /gene="murN"
                     /locus_tag="VWX64_001008"
     CDS             complement(15627..16859)
                     /gene="murN"
                     /locus_tag="VWX64_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU9190489.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(16864..18084)
                     /gene="murM"
                     /locus_tag="VWX64_001009"
     CDS             complement(16864..18084)
                     /gene="murM"
                     /locus_tag="VWX64_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU9190490.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(18196..18975)
                     /locus_tag="VWX64_001010"
     CDS             complement(18196..18975)
                     /locus_tag="VWX64_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU9190491.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(19044..20705)
                     /locus_tag="VWX64_001011"
     CDS             complement(19044..20705)
                     /locus_tag="VWX64_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9190492.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(20880..23102)
                     /gene="recJ"
                     /locus_tag="VWX64_001012"
     CDS             complement(20880..23102)
                     /gene="recJ"
                     /locus_tag="VWX64_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU9190493.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNTVLPEGVPVLDFPGELPNLAASEAVVVKNIPESITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            23379..24137
                     /locus_tag="VWX64_001013"
     CDS             23379..24137
                     /locus_tag="VWX64_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9190494.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            24148..24942
                     /locus_tag="VWX64_001014"
     CDS             24148..24942
                     /locus_tag="VWX64_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9190495.1"
                     /translation="MKKKFFLSALLISLFGLVAAKPVQANTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIHYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            24955..25632
                     /locus_tag="VWX64_001015"
     CDS             24955..25632
                     /locus_tag="VWX64_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9190496.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            25642..26301
                     /locus_tag="VWX64_001016"
     CDS             25642..26301
                     /locus_tag="VWX64_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9190497.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            26538..27662
                     /locus_tag="VWX64_001017"
     CDS             26538..27662
                     /locus_tag="VWX64_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU9190498.1"
                     /translation="MEFSMKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSL
                     TFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNL
                     AIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFL
                     VGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQF
                     AFLKIFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYG
                     HMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNY
                     AQKNPNFELHLIDSTKDGYLNFEQKKCPNMQPSICVVLFL"
     gene            complement(28060..28941)
                     /locus_tag="VWX64_001018"
     CDS             complement(28060..28941)
                     /locus_tag="VWX64_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU9190499.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(29082..30410)
                     /gene="vncS"
                     /locus_tag="VWX64_001019"
     CDS             complement(29082..30410)
                     /gene="vncS"
                     /locus_tag="VWX64_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU9190500.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKNRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(30407..31063)
                     /gene="vncR"
                     /locus_tag="VWX64_001020"
     CDS             complement(30407..31063)
                     /gene="vncR"
                     /locus_tag="VWX64_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU9190501.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(31112..31195)
                     /gene="pep27"
                     /locus_tag="VWX64_001021"
     CDS             complement(31112..31195)
                     /gene="pep27"
                     /locus_tag="VWX64_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU9190502.1"
                     /translation="MRKEFHNVLSSGQLLTYKRPARDYNRK"
     gene            complement(31376..32755)
                     /gene="vex3"
                     /locus_tag="VWX64_001022"
     CDS             complement(31376..32755)
                     /gene="vex3"
                     /locus_tag="VWX64_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU9190503.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(32807..33454)
                     /gene="vex2"
                     /locus_tag="VWX64_001023"
     CDS             complement(32807..33454)
                     /gene="vex2"
                     /locus_tag="VWX64_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU9190504.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAALDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(33467..34744)
                     /locus_tag="VWX64_001024"
     CDS             complement(33467..34744)
                     /locus_tag="VWX64_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190505.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9898 a         7906 c         6456 g        10556 t
ORIGIN      
        1 ttttagcaat tgtttcgtac tattttagat tcagtctact atacataaac taacctcctc
       61 attattagca aggcttctac tgattataac ctaattctta gactacttca agactaactg
      121 tccaataata atctacagat aaatcatcca ctcttaatca aattttattc aatccatcta
      181 ctcattccca aaaggttgct gtataatgca agacattttt cttactgctt ttacttttcc
      241 ttaccctcaa tttagtgagc taataaatta ttcttcttca aaaggttgag atttatctag
      301 taactctaaa acattaatgg taggtagcaa cattgcttca ctgctatcaa ttgccgaaac
      361 tattgaaaca atagaacgta aataaggaca aagaatagca gtaccattta cgtatagaat
      421 atcggtgata ttttcatcta tatttatttc aaaatatcct attacagtta cagatatttt
      481 ttcatggcat ctttgtcaac taaagaaaca ctaagtttta cggctccatg actataatca
      541 tctgtatgac caaccttaac tatgggatat aatatatcga aggtaaatgt gaacaaactg
      601 attagggaat ttaaaccaac ttctaacaat gtgttatact caatgaaaac caaagagcaa
      661 actaggaaac tagccgcagg ttgctcaaaa cactgttttg aagttgtaga tggaactgac
      721 gtagtcagct caaaacactg ttttgaggtt gtgaatggaa ctgacgtagt cagttcaaaa
      781 cactgttttg aggttgtgga tggaactgac gtagtcagct caaaacactg ttttgaggtt
      841 gtggatagaa ctgacaaagt cagctcaaaa cactgttttg aggttgtgga tagaactgac
      901 gaagtcagta accatacgca cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa
      961 gagtattaga aagctcgatg gactattcca gattcattcc actagatttc gaaatcgagt
     1021 aggggataat ctctagcccc tctcacacca ccgtacgtgc cgttcggcat acggcggttc
     1081 aactaacttt taacgcatgt cgttcaaggt aataatccaa acacgaaacc agtccacgtt
     1141 tttcaaggac tggttttgat atagcacgtt taagtaccga cttctgagct actatagtag
     1201 attgaaacta gaatagtaca cctctacttc taaaacattg ttagaaatcg atttgactgt
     1261 cctgaacgat tcgtcctatt cttatttcat tttactataa ttgatagtgg tcgccccagc
     1321 cagatacctt atccgctata taggccttat tatcacgttc ctgttcgtag agccacgatt
     1381 tcgctatccc ttcctctgac gattcttatt tccagcgtca gacttaaaac ggtctatccc
     1441 cagaccgttt taatccgcta cctcacgata gtcagacttg ggaatcgcta ttgggttcac
     1501 cagtagtagg tgcccaccga ggactcacac ctcagatata cgacatgccc gtcgtacatc
     1561 aaaaaaagtt gagacatagc gtcttcaact tttttacatt actttaacta ctgattaaag
     1621 tgagtttacg tcaactttga taccaacacc ttgagtagtt gtgatagtca agtttgttac
     1681 gtaagttcct ttagctgtag ctggttttgc tttttggatt gtttcgttga aagctttaaa
     1741 gttttcaacc aatttttcag cttcaaatga tactttaccg atgattgctt gaacgttacc
     1801 tgcacggtca gcacggtaag tgattttacc acctttagac tcttcaactg ctttagcaac
     1861 atccattgtt acagtaccag ttttagggtt tggcatcaag ttacgtggtc caaggacacg
     1921 tccaagacgt ccaacaagag ccatcatatc aggtgtagcg ataactacgt cgaagtccaa
     1981 ccaaccgtcg ttgattttag caacaaggtc atcttcacca acaaagtctg caccagcagc
     2041 ttttgcttct tcagcttttg caccacgtgc gaaaacaaga acacgtgaag ttttaccagt
     2101 accgtttggc aataccattg ctccacggat ttgttggtca gcttttttaa cgtcgatgtt
     2161 caagttgtaa gcaacttcta cagttgcgtc aaattttgca aagttagttt cttttgcaag
     2221 agctacagct tcttctacgc tgtatgcttt tgtgctgtcg attttctcaa gagcagcacg
     2281 aagttgtttg ctttttttag ccattttcta ttctccttgt aagtggttca atcgattttc
     2341 atctcccacg tcacttctcg aaatgatgaa gtcttgcggg ttttcagtct actatttttc
     2401 tcctcctacg gccttaagct cccttgctgt acccaagtac aagcctcagt cacttgccta
     2461 gtatgaaaag caactaatag actgctgtga gattttctac tgtgttattg attagtcaac
     2521 aacagtgaat cccatagaac gagcagtacc ttcgatcata cgcattgcag actctacgtt
     2581 tgctgcgttc aaatctggca tcttagtttc tgcaatttct tgtacttgtg cacgagtaac
     2641 tgtagcaact ttagttttat taggtgtacc tgatcctttt tcaacacctg cagctttttt
     2701 caaaagaaca gcagctggtg gtgttttcgt aacgaaagta aatgatttat cttcgtaaac
     2761 tgagataaca actggaatga tcataccagc ttggtcagct gtacgagcgt tgaactcttt
     2821 tgtgaatccc atgatgttga taccagcttg accaagagca ggtccaaccg gtggagctgg
     2881 tgtagcttta ccagcaggga tttgcaattt tacaagtttt tcgacttttt tagccatttt
     2941 taaatcctcc tttgtggttt tggcggtaat tagagatttt tacctcccac aagtatgttt
     3001 ttcacatacc catccattat acactattta tctggaattg caagagaaaa gtttattttt
     3061 tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cacaggctgc tcaaagtaca
     3121 gctttgaggt tgcagataaa actgacgaag tcagctcaaa acactgtttt gaggttgtga
     3181 atagaaccga cgcagtcagt aggtaaggcg acgctgacgt ggtttgaaga gattttcgaa
     3241 gagtattaat cgacgtagtc tccgccttca aagccatagt attcttccaa actgagacca
     3301 cttgcagcaa tttctttagc ttcttttcct acataacgca ggtgccattc ctcagccata
     3361 tagcctgttt ccttttcctt gcctttgaga taacggacaa caaagccata atcagctgca
     3421 tgatccaaga gccattgggc tgctttttct tctgtcacca aatcaccatc agtcccaatc
     3481 acatcaaagg ccaagcctgt ctggtgttcg ctatagccag gacgggcaga gtaacggtca
     3541 gctgctgcct ttccatcttg gttgacataa tcttgataga gcttggtctg agtttcataa
     3601 cttctaaaac cactgtaatg atcactaata gggaaacctg cctcttgcat cgctttgatg
     3661 agtttgacca actcagcctt ggctgttgga ttttccccgg gattatagtc tttcgacaaa
     3721 ggataatgtt tattggctac gatgatttcg tcgtattttc cttggatgct gtagtaatca
     3781 cctttattga ccacttctgc ttttttctgg gcagcccctt gagacttact gccgactgtc
     3841 ccatcagctt tggctgtctg ttctgtctta gctgtgccat cttcattttt tgctttttct
     3901 tgtgaacaag ctgctagact caaggctagc aaggctgtca cgacaaggta tcttttcttc
     3961 atttctactc ctttatttct aatagtttat ctacttctga tgataaacgt ttgactaatc
     4021 ttttaataga cttcctgcaa aactagaatc ctagttcatg attgataata ccagcaatca
     4081 aattcattcg taatccgaag cgtttacgat gatttcgata ggttgttgaa aacattttaa
     4141 acgtttttac tttggcaagg atgttctcaa ccttgcttct atccttagat agcgcatggt
     4201 tataggcttt atcttcagct attagcggct tgagtttgct ggatttacgt ggagtttgtg
     4261 cttgaggata tatcttcatg agcccttgat aatcactgtc agccaagatt ttaccagctt
     4321 gtccgatatt tctgcaactc attttgaaca acttcatatc atggcaatag aaacaattct
     4381 cccttgactt gtgacaatcg cttgagcctt catagcgtga aatttctttt taccagaatg
     4441 attcgctaat tgttttttag ggcgattgat ttgtacttcc gtcgcatcaa tcattaccgt
     4501 gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa gagttacttc
     4561 aacccatcgg ctccgacgga ttaagttgct ttcgtggata ccaaaatcag ccgcaatttc
     4621 ttcataagtt cgatattctc gcacatattg aagagtggcc ataagaaggt cttctaggct
     4681 taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt ttaatacagc
     4741 taacatctct tcaaaagtcg tgcgttgaac accaacaaga cgcttaaatc gtgcatcggt
     4801 tagttgttta cttgcttcat cattcataga actactatac catattttat ttcgcaggaa
     4861 gtctgatctc atccggtttt gcttgacggg tttctgcggt tatttcttca aaagggaccc
     4921 accagactgg cccacagccc ttgagaccgt ggccattcat atcacctctt cgtctaggga
     4981 aaaggtgcca gtggagatgg gcatcgccat ttcctagaag ttcaatattc attttctcag
     5041 cagtaaaggc cttggcaact gcctcttgga ctaaactcat ttcttctaga aaatggagtc
     5101 ttgtgtcctt ttctaaaatg gtgcaattcc gtgacatgtt ccttggctaa aaagagacta
     5161 tagcttgcaa aatactgatg gtctccaatc acaagatagc ctgtttccaa ctctttgaca
     5221 aagtagggat tttctccctt cttgatgagc tcaattctct ggcaaataag gcacatatca
     5281 atctactaaa ttgcttctaa gataggcatc gaccattcgt tctgttgcga ccaccgagtc
     5341 aatatgagtg cgctcataag aatgactaga ctcgataccc gcaccaagaa gggcatgctt
     5401 gacctctgcc cctgcagaca tagccgctga agcatccgaa ccataaaatg gatagatgtc
     5461 cagcttaaaa ggaatatctt gctctttagc caaggcaacc aagtgttgac ggaagtcata
     5521 gtgataagga cctgaagcat ccttgacaca gatagatact gtgtactcat ctgtctgctg
     5581 gtcatctccc atagctccca tatccacagc cagatattct actacctgag caggaatgtt
     5641 agaattagca ccatgtccta cttcttcaaa aactgaaaaa ccaaaatgag ttgttactgg
     5701 caattcaatc ttctctttct tataaatacg aagcaggttg agcaaaatcg ctgcgctgac
     5761 cttatcatcc aaatgacgag acttgataaa acctgtatca gtcacaacag ttcgtggatc
     5821 gaagctgata aaatcaccga cctcaatccc aagagcacga gtttcttttt cattgcttac
     5881 ttttacatcc aaacgcactt ccatattgtc ctgcgtgcgt tctgcagttc ctgcatcctt
     5941 gtagacatgg caagaagttt ggtggatgag gatggttcct gatacctttt gacctgtgct
     6001 agccacatga acggtacagt tttcaccttc aatcatgttc caaggaaaac caccgatacg
     6061 gtccaattta agacgaccat ctggtttgac agcacgaaca atagcaccca gcgtgtccac
     6121 atgggcagtc acatagcgat gttgcccatc attttgacct ttgatggtca cattgacacc
     6181 acccttggct gtgcgaactg gctggtaacc aaaaccttct agagtcttga ctaaataatt
     6241 cgaaatttca cgagtgaagc ccgttggcga tgcgatggct gtcagttctt tgatatattc
     6301 tactgtttga ttcatttctt cacctctttc gctacctatt ataacacatt tatcatcgga
     6361 taaaaaaaga aaatcactcc tgtagacttg gctacaaaag tgatttaagt gattattcca
     6421 tttcaaaaac atcgctttct tgcttgtttg gtagaaccaa tgagagcaag attccaacaa
     6481 tggctggcac caaccatggg agagatgcct tggcaaaagg aagaacgcta acaagatttg
     6541 caagaaactc aaccttaaac gagcttccta gtacgcttgc aatggcaata actgtaacca
     6601 cagcaattgt caactgcata cctggttttg aaagggcaac aaatttgttg acaatgacaa
     6661 tcataacgat agcaatcgtg attgggtaca agataaccag tactggaatt gagtacttga
     6721 taatcgcatc aagacccaaa ttggcaatag caaatccaat caaggtaaag gctgtcgcat
     6781 aaaccttgta gctgatttgt gggaagcgct cattaaagaa ctcagctgtt gacacaatca
     6841 aaccaacagt cgttgtgaag caggttacgg taaccatagc tgcaaggaag agttgagctg
     6901 ttgagccaaa gatttcttga gtggcttgtg acaagatgta aacacctggt gttccaccct
     6961 tcatcgcttc agctggtact gggaaatgat ttccaagaaa acctaaaccg atgtaaagag
     7021 cgctgaaggc aagggcaaca acgataccaa caacccaaat agttgaaatg tattctttct
     7081 tacttgaaaa tccaagttgt ttcaaggttt gaactgcgat tacgctaaag gccactgagg
     7141 caagggcgtc caaggtattg taaccttcta ggaaacctgt accaaaggca gaagcttgat
     7201 aagcagctga agcagcttga ggacttgttc caccatattt gatagctccc agaacgacca
     7261 agataacaat caaaattgca aagactggcg ttaaaatacg tccaatgcgg tctaagattt
     7321 ttgatggatt aagcgaaatc aaataggctg ccgcaaaata cagaaccgta aatacaatca
     7381 cgccaagtcc tttatttgca tccgacaaaa gggggctaat ccctacttcg taagctgttg
     7441 tagcagtacg tggggtagca aagaatggac cgattgacaa gtaaagaact gagaggtaaa
     7501 gagtcgcaaa ccaaggcgct atcttcgttg aaatctcgta gatatatcct ttaggattta
     7561 gcgttccaat aataagggtc aagacggcga taccaacgcc tgaaaagaca aaacctgcga
     7621 tggcaggaag aaaatgttct ccagatagag cacctagaga aggcggaaaa atcaagttcc
     7681 ccgcaccaaa aaatattcca aacaggagca aacctgttag ggtacctttt ttagccataa
     7741 aaatctcctt catatttata aaatactgac ctagtatacc acgattagga gtctgaaaaa
     7801 agcatcacga ggcaaatatt aaatgttttc aattttctta aaaataagaa ttatctaaaa
     7861 ataaaactct cctacccagt ccacaccaag taggagaaat gcaaaatttt aaagttcttc
     7921 aaaggctaac atgccaccct ggacattgat aacattataa ccttgttcta acaggaattg
     7981 gcaagcacgc gccgatctca ttccagattt gcaaataata taatgcaagc gatctttgtc
     8041 caattaatca taactatcag ccaattgact aagcggtagg ttgtgggcac cttctaaatg
     8101 aagagctgca aactcatcca cttctctcac atccactaga gaaagctggt aaaatgcgtc
     8161 aaaggctatt tctttcattc tttttcttct aatactcttc gaaaatctct tcaaaccacg
     8221 tcagcgtcgc cttaccgtgc gtatgttacc gacttcgtca gttttatctg caacctcaaa
     8281 gctgtacttt gagcagccta cgactagctt cctagtttgc tctttgattt tcattgacta
     8341 taaatggttt taattctttt tttcaaatct ggcactactt ctgcctcaaa ccaaggattt
     8401 ttggccatcc agatttgatt tcgtggtgat gggtgaacta gcggaaaata ggctggcaga
     8461 tagtctttat agtgtttcac cctctccgtt accttcccac tgattttctc ctgtaaatag
     8521 taggcttggg catattgccc aatcaagagg gttaactgaa tatcaggcaa ttcctgtaag
     8581 agctgcggat gccatttttc tgcaaaacct gtacgaggcg gaagatcacc cgacttgcca
     8641 tgtcctggaa agtagaaatc cataggcaaa acagcaaaat aacctgaatt gtaaaaggta
     8701 tcttcatcca cacctagcca gtcccgcaag cggtcaccac ttttatcttt ccagtaaagg
     8761 cctgcttctt gagttttaag tcccggagcc tgaccgatga tattgatgcg agcagttttt
     8821 ggcgctgcaa agagaggctc aatgccacgc tctgtatagc tggcattctg tgaatccgcc
     8881 atgatagcct gtttgattct ttcgatttga gacatctact ttccctccaa aaagaagtcc
     8941 aagcataaga tctcagactt ctatcgtttt atttgatcaa ttcgtaaata gcttcggcat
     9001 aaattgctgc tgctcggaag agatcatcca aggcaataaa ttcattggct tggtgcatgg
     9061 tatcaattga gtctgggaac atagcaccat aggcaactcc gcgctctaac aagcgaccaa
     9121 aggttccacc accgatgact tgttcatgac ctttaaggcc tgtttgtttt tcatagacat
     9181 tcaacaaggt ttgcacaagt ggatcttcca ttggcacata gtgaggcgtg tgaccgtgtt
     9241 cagacaggct aacagaaaca actggcaagt tttcaaggat tgacttgatt tgttctggac
     9301 ttgttccttt tggatagcgg atgttgaggg caatggtatt atcagcactt gtttcatcga
     9361 agcggaagac gcctgcattc atagaaaggg cacccatctt ttcatccaca tgagcaatct
     9421 tgagactttc accctcatgg tcgttcaaga gaattttacc agtgatgtca aggtattctt
     9481 tggctggacc agcaaagtca aactggctaa ggaagagggc taggtaagtc gcaccattga
     9541 cacctgaagc aggcatagca ccgtgggctg atttaccaat gatcgtcacc ttgtatttgc
     9601 cagcttcttc ttggagttct cctctaagtt tgtgttctgc aacaaaggca tctagtttag
     9661 cttgcaagtc agccaaatca cctgaaacga ctgctgttgc tgattctggt accatatttt
     9721 cacgtaaacc acctgtaaag ctgtgaagac gggcagcacc tgtattttct cctgcaaagt
     9781 ggaggtattc cgtgatattt cctttttcac cattgatgat agggaattca gcgtctggag
     9841 agaaaccgaa atctggtttg gcaagtccta cgtgctcaaa gtagtagtcc atatctgccc
     9901 agcctgattc ttcgtctgtt ccaacgatga agcgaacttt cttagaagtt ggaagaccca
     9961 attctttgat gattttcaaa ccatagtaac aagctgttgt aggaccctta tcgtccgaag
    10021 ccccgcgcgc ataaaggcga ccatctttga tagttggtgt gtaaggatct gtatcccaac
    10081 cgctaccagc tggaaccacg tccatatggg caaagattcc gagaacttct tctccatcac
    10141 caaactcaaa atgtcctgca tagttatcaa catttttagt tggataacca tcacggtctg
    10201 cgatttcaag gaatttttcc aaggctttta ctggaccagg tccaaatgga tgttgggcat
    10261 cagccttgct atcatcacgt tctgagttga tttccaaaag gctaaacaag tcagccaaga
    10321 ggtcttcttt gcgtttttct acttctgctg taaaatcaat tgctatcatt ttttcttctt
    10381 cctatctttt ttcgatgatt tcatctactg gcaagcggta gcttggttcc aatttgtcgt
    10441 ctgtgtaacc cactgtgatc aagagttctg ggcggaaacg gtcttcgatt tccaaaactt
    10501 cattaacttt tgatttgtca aaaccaagga taatattgga accaattcct tggtctgtaa
    10561 gagcgagaac caagttcata gcaaccaaac ctgcattgag tgctaggtag tcgctgactt
    10621 gttgttcatt gtagcgtgca aattcagctg gcaaattttt catgaagtat tgaagttgtt
    10681 cttctgagaa attgttagca ccaccaactc gggcaatctt acgagcgcgt ttggcaaggt
    10741 ctgtatctgt aaatagggca atggttacag gtgctgatga tacctgttca aaattggaac
    10801 cataagctaa ctttgccagt tcagcatttt tctcacgtac caccacaaat ttccaaggct
    10861 ggctgttgtg ggcgcttggc gccaaggttg caatttcgat agccgtacgc acatctttgg
    10921 gatcaacagg cttatcagta aaatgcttgg tcgcatgacg ttttttattt aattcaagaa
    10981 atttcataat cgatttcctt ttctaattct actgcttcca ttctaccata atttgaaaga
    11041 gcttgcaggg atttttcatg attaagtttt tctatcacag acataaaaga tatatattgg
    11101 tttatcagga aagtttctga taaactagca agtactttac atttgaatgg agacagtatg
    11161 aaaaaattta gcctattact agctatccta ccatttttgg ttgcctgtgg gaatcaagct
    11221 acacccaaag agactagcgc tcaaaagaca atcgtccttg ctacagctgg cgacgtgcca
    11281 ccatttgact acgaagataa aggcaatctg acaggcttcg atatcgaagt tctaaaggca
    11341 gtagatgaaa aactcagcga ctacgagatt caatttcaaa gaaccgcctg ggaaagtatc
    11401 ttcccaggac ttgattctgg tcactatcag gctgcggcca ataatttgag ttacacaaaa
    11461 gagcgtgctg aaaaatacct ttactcgctt ccgatttcca acaatcccct cgtccttgtc
    11521 agcaacaaga aaaatccttt gacttctctt gaccagatcg ctggtaaaac aacacaagag
    11581 gataccggaa cttctaacgc tcaattcatc aataactgga atcagaaaca cactgataat
    11641 cccgctacaa ttgatttttc tggtgaggat attggtaaac gaatcctaga ccttgctaac
    11701 ggagagtttg atttcctcgt ttttgacaag atatccgttc aaaagattat caaggaccgt
    11761 ggtttagacc tctcagtcgt tgatttacct tctgcagata gccccagcaa ttatatcatt
    11821 ttctcaagcg accaaaaaga gtttaaagag caatttgata aagcgctcaa agaactctat
    11881 caagacggaa cccttgaaaa actcagcaat acctatctag gtggttctta cctcccagat
    11941 caatctcagt tacaataata ctcttcgaaa atctcttcaa accacgtcag ctttatctgc
    12001 aacctcaaag ctgtgctttg agcaacctac ggctagcttc ctagtttgct ctttgatttt
    12061 cattgagtat aagatatact aaaagcgatt ggaccagcca atcgcttttt tagtttgcat
    12121 tggttatttt aggaaactct tacaaaaaat caaaataatc tttcacatcc tctacatacc
    12181 catgcttttc tattaagctt gctaaaagtt ccagattgtg tccctgatag ttatcttcac
    12241 gacgtagttc ttcatacatt tcgataaagg gaagcccctt ggacttggcc aattctaact
    12301 cagcctcgta atcataagca actttacgaa attggatatt gaccaattcc ccgtcttcaa
    12361 cttctatcac ggcatactgg gcacggtgat tttttaacgc ctcccaatta aaatagggca
    12421 tgccaatcga ccctggattg atgatttgtt gcccttgact tccataacga agcaactgct
    12481 tgtgaacatg accataaact gccacgtccg tttccgcatc tagcagttgg tcaaatttct
    12541 ctgtatcatt ctcaactagc aagtcaccac catagttttt gtcaggtaaa ttatgagaga
    12601 tagaaaagtg caatccgtca atttctttct tttccagcaa aggcaagctt cgtagccaga
    12661 caatcgttgc aggatccatt cgctccatca aaaactgggt catgcgcatt gactggattt
    12721 ctttcggata ttccaaacca tattcgccat ccaagacctc aaggacacga tcatcccaat
    12781 tgcctcgaac acttgctgtg ataggaaggt cctttagcag ggcgactaag tcatttgcgc
    12841 ctggaccagg aagaaaaata tctcccagaa gccagtattc actgactcct tgatttttag
    12901 catctgcaat cactgcttct agcgccgtca cattgccatg aatatctgat aaaattgcga
    12961 ttttatggtt cattgtggtt tccttccgtt tggtaatcta ctctttcttc tgctacttga
    13021 ggcaaggctt ctccctgcgg gttcaacttt ctttgcacag cctctgcaac gactctaggt
    13081 accccaactt cgacaatctc atccacactg gcttccttga ttttggtcaa agacttgaaa
    13141 tgcttcataa gattctgctt gcgtttaggt cccagaccgt caatcccatc caattgagat
    13201 gagaaagaat ttttggagcg cagttggcgg tggaaagtga tagcaaagcg gtgcacctca
    13261 tcttggatgc gttggaggag gaaaaattcc tgagaattgc gagacaagtc caccacctca
    13321 agcggatctc caaagagcaa ttcatgggtt tggtgcttat cattcttttg cagcccagca
    13381 attggaatat ccaagcccag ttcctcttgg ataacctgct tagcgatatt gacttgacct
    13441 tgccccccat caatcacaat caaatctgga ggagtcaaag cctcacgctg tactcgacca
    13501 tagcgtctgc gaatgacctc tctcatgctg gcatagtcgt ctggtccaac aaccgttttt
    13561 atcttgtact tacggtaatc cttcttactc ggtttaccgt tgacaaagat caccatagcc
    13621 gaaacagggc tagttcccat gatattagag ttatcgaagg actcgatacg tactggggtc
    13681 gggatttgga gcaaacgccc tagattttca atagctcctt gagtcttttc gacagatttt
    13741 tctagcaggt taaatttctg ctccagacta acacgtgcat tttttatggc tagattgacc
    13801 agttgttttt tctctccacg ttgaggctta agaatcttgg aatccaccaa ggccttgaca
    13861 gcctcttcgt caatatcctg cggaatcagt acctcattgg gaactagatg agatttttct
    13921 tgatagaatt gtcctacata ggtcaaaaaa tcctcatctg gatcattgaa gtaggggaag
    13981 agattgacat cgcgctcgat aagcttaccc tgacggacaa agaaaacctg cacacacatc
    14041 cagcccttat ccacatagta gccaaagaca tcgcgatttt gcaaatcttt cgccatgacc
    14101 cgttgcttgg ttcgaagcgt tccaatagcc tgaatcaggt cacggtattc cgccgcacgt
    14161 tcaaactcca tactttgtgc tgctactgcc attttactct tgagatcatc gatgattttg
    14221 ttatcctgcc ctttcagaaa atcagaaacc tcctgggcca tagacttgaa ataagtctca
    14281 tccttcttac agatggtgtg ggccatgcat tgaccgatat ggtaataaaa acagacctta
    14341 gagggcgggt tggtacactt acgaaaaggg aatatccgat ccagcaaccg cttgatttca
    14401 ttggctgccc ccacatcggg atagggtcca aaataaagac ctccgtcctt tttgacctga
    14461 cgagtgataa tcaagcgtgg atagcgctca ttggtgattt tgatgaaagg ataggacttg
    14521 tcatccttga gcatgatatt gtacttgggc ttgttttcct tgatcaggtt gatttctagg
    14581 agaagtgcct caatattaga ctccgtaaca ataaattcaa aatccacaat ttcagacacc
    14641 agagcctctg tcttggtatc atgacttcca cgaaaatagg accgtactcg attacgcaga
    14701 tttttagcct ttcctacata gataatggtg ccatttttat ccttatgaat gtagcaacca
    14761 gggctggtcg gcaagagctc tagttttgat ttaatcaagt tgttcatagt tccattatag
    14821 caaaaaaagt agggaaagat agtaccctac tcattagtct catatatttt tcggaggttt
    14881 gcaacatcct cttcctggat accataaaag gaacctgctg gttgcatgac agacttctca
    14941 tctgtatggt ccaagccaat cgcatgacct aactcatgtt ctgccgtatg gacaaggcgt
    15001 tcataggaat agccatagta tggattggac aaataataat gattcaaccg caccgttacg
    15061 gacaagaatt gccctgttaa gagattagtt tgactttccg cctctcctgc cacaggagtg
    15121 cctccgtcgt tcatctccgt agccgtaata tccgccttac tagactcagt cacgagttca
    15181 aagttaaaag caccagtttg attccagttc tggattgctt ctaaataagc ctcttgaaag
    15241 cgtgaatcca tctgcggatc caggtaaata cgagcagagg cctgtggcca ccttccttca
    15301 gaatgctggt gactatctgt ctggcttaac ttaggcagtt gccctgtttt ctcccattgg
    15361 tcaatacttt gttgaccaat ttttactgac cgttctgctt gctttagcgc tccttgaaaa
    15421 tccccgttca aataccagag aagtccgaaa gcaagcacac ataagagcac aactatccaa
    15481 accagacgcc aaaacaaacg ccacacaaaa aaaaagaaag cccctatcaa acgaaaaagc
    15541 cagcgcatgt ctctccacct ttctagcaaa taaaaattat tttactaaaa gaagctaaaa
    15601 gaaatctaaa tactgacttt ttcatcttaa cgtcctacta tttttttgag taactggata
    15661 gctttgtatt ttaaaggcga tggatggtaa cggaaagtac ccgctttgcg tacaatatag
    15721 ccattaaaat tctgtttaaa acgcaaaaca ccatcacttc catcaaaaat cccttgaatg
    15781 cctaggaaat tgtatttagg tattccacgt tttatgcttt ccaacataac atatttttga
    15841 agcagtgcag gggcatagaa cttattaaac tcagtgtagg aaccactaaa gagataagtc
    15901 gtttcctgag gcatataaac aaataaactc ccagctaaaa caatatcttc ttctccatat
    15961 ttttcaatca agtctcgcgc ttctgctttt cgaacttcaa acgtttcaaa ttgactagaa
    16021 tattctctca gttgattttg ttttttctca gaatgaggat ttttactcaa atcaagtcgc
    16081 aacttgtcca agttttcttc tagtttactt tgttcacctt gcaatttgct catatactcc
    16141 gaaaaattca agcttgctat gagaaactcc gcttgttctc caaaagtatc ataaaaatgc
    16201 tcataatatt ctaaactttt atcactatat tctctacgtt cagaggtttc ttttgttata
    16261 ttcttaaaaa tcgatagttc ttcacgtttt aactttttca accgaatgcc aaaggtttca
    16321 gcctttttca ccaagggttt accctttttg ctaaaacttt taagcaaact cttttcagtt
    16381 aattcagtta aatctttata gtataaccaa tctggttctc cacctgggta acctgttgtt
    16441 aagccatcaa attgataacc taaatcagtc aaaccttgaa taatactttt tttctcagca
    16501 tctattggat taccttggct atcaaaagtt tgataagttt cataaggttt tacaagcaac
    16561 tctaatacac cattttgctt ggcatattct tttaactctg cataaaaaac tggaagagca
    16621 tcttgttggg tataaatcgg ccccgaattg agttccatat gcagaccacc cagcatgggc
    16681 aagctataaa ccagagctgc aacttgaatt tctccttctt gtttcaaagc aagataaaca
    16741 attcgagccc ctcttttttc tagcaaatcc cccatctgga cagattgcat aaaggaacga
    16801 gaagaaacct gatcagaata agtctgaaac tcttctttcg tgagtgttgt tagtgccata
    16861 tacttacttt ctatgttttt ttcttaatgt tttacggaaa tcaagagcaa gtcttaacag
    16921 aggatagaga ggatgagtgg gcattgtaaa ttcacccaag tattcttcaa tcgttggatt
    16981 aaatttttcc ttaaaatgat aaagtccacc attgagagag ttttcaacac cacctaaatt
    17041 ttgccagacc atacctcgct caaaggcata gcgagccgtt tcataccatg ttaaaattgg
    17101 tgcattgtaa cgtttaaaat catcatccat accagcatat atattgacag aggtagtacc
    17161 aaattccaaa ctcaaagtag ccgctaaagg aactctcgct tgacctacat ctatatattc
    17221 ctgcaagaag gtcaattcct ctaacaaacg ttctttttcc ttcttctgcg cttctacttt
    17281 tgaaattcga gtcgactcag taaacgtctc ttccaaggct ctatttttcg ctaactgttc
    17341 ttctaattct tgcgaacgtt tagaaacatc caaggtggcc aaggtgatat aggccttgtc
    17401 cttaaaatta tctaacaatt ttttataata ggcttcattc ctcaaatgaa tctcttttcg
    17461 cttctcagtt tttttcatca actccgaaaa tgaatctaat agttccagtc caccatattg
    17521 aatctcaagc cctttgtttc gtgctgttcg aatagcctgt tttgttgact tggaaagttt
    17581 atcttcttca aaattttcct tgtatatttt cgcctgaata cgaggttgaa tggtgtctcc
    17641 catttcctcc gtttttcctg accaccttac tcccatttgt tgcaaactat caataatagc
    17701 cagattttca ggaaattctg tcttttcctg attgattaaa ctttgagata ggcaaatact
    17761 tgggtcaaaa gtcacaaaaa ccgctctctt actgcgagca taggacttaa tagactgaat
    17821 ggcaaaattc aagagttctt tatccccata atccaatata ggtcctcttg ggatgtaaaa
    17881 cattttatag cctagcggaa gagttctaat caaaatacta gctgtcgcca gtaatttttc
    17941 ttccctgtaa acaccaaact tctcatgttg ccaattagac ttaacttcct cccaagcact
    18001 actttgtaat acattggcta attcatgttc tttgacaaac tgatcatatt ctaatgtggg
    18061 aatgccaatt tgataacggt acatttccta ctctctttcc tccagtattt tattactatt
    18121 ctactacttt cgtttgaaaa gtctagtgaa aacatatttt attttagttc tactccccct
    18181 atgctgaagt tcaaactaag tcagtctctc ttctaatttg aaatcaattg gtagggttgt
    18241 taaaaaaact tccaattgtt tttcccagta gtaccactcg tgagttccag cactatggct
    18301 ataggtcaca tcaaaaccta gttttttgag atttttcact gcgagattat tggcttcgta
    18361 caagaaatcc tgttcgccac accacgccca aagtttggtc tttttatccg attttttagc
    18421 cagactttca agagaatagg gactagttgt ccagtctcta atctctccaa aaacacctct
    18481 ccagtaggct ggacttccca gattttgact ttcaggagaa aagttttgaa agctgagggc
    18541 acctgaaaaa ctagctgcat gagaaaaacg atttgtcgta agagccagtt tgaagcagcc
    18601 gtagcctccc atagaaagac cagcgataaa ggtcttttca cgcttgctag tcatattagg
    18661 gaagaagcgt ttcagaacct gtggcaattc ctctgctaga gccgtgtagt agtcaaaacc
    18721 atactgggtg tcggtgtacc aaccattgct ggtattgggc ataacaacga tgagattagt
    18781 tcctcgaagc aagcgttcta cattggtccg cttaagccaa ctattatgat ttccagacat
    18841 cccgtgcaaa aggtacaaga cgggaatatc ttcacactct ggttcttcca ctcgattggc
    18901 atcagggtag aggacattca ccccccactc catatccaat acttgtgagt aatactcgat
    18961 tttcattact gccatgattt tctccttcta tttttctata agaaaaagcc gaaactcgac
    19021 tttctctctg tttatttcaa cgattatttt gcttccatga ctactggtaa aatagctgga
    19081 cgacgcttgg tttggtcaaa gagatacttg gtcaaattat ctcgaacctt ccctttaaga
    19141 tctgcccagt caaagtcatc tccttgaaga taatcttcta ccgtttggtt aatcaattct
    19201 gaactttcac ggagaatatc gcgactcttc ttgagataaa caaatccgcg cgtatgaaca
    19261 cgagccctag ccacaatttt cttctcacga cggttgactg taatagccac gatgaaaatt
    19321 ccatcctctg acaagacctt acggtcacga agaacaacat ttccaacatc accaatggca
    19381 ttcccatcaa ttaagatatc tcctgctgaa accgatccag ctggaacaaa gtctccattc
    19441 tcgtaagcca tggtcgtccc ctttttagga atgaagatgc gttctggcaa catcccaact
    19501 gccatggcag ccttagcgtg agcatccaac tcacgatact ccccttggac agggaagagg
    19561 tacttaggtt gcaaaagatt gatcatcagc tgcaaatcac gcacatttcc gtgccctgat
    19621 acatgtaaac tttgggtaat caatttgaca accccacctg cctgataaat catattttcc
    19681 acacgcgcaa caaaggcttc tttagcaata gacggagccg tagcaatata gaccaggtcc
    19741 ccatccttga tttctacata acgatggcga ccaatcgaca tcttacgaag tccattgata
    19801 ggttcaccca tacgacctgt ctcaagaata atcaactcat ggtcttcaaa gcgagacata
    19861 tctttaggct taatcaagag aatttcgttg gctaaagaca acttcttaag acgaatcgct
    19921 gtgcggacga tattttcaat atcaaatcct gtcaagacga tacgtcgacc tgttttatcc
    19981 gcagcgtcaa aaatctgctg aatacgagaa agattactgg aaacagctgc aacgatgata
    20041 cgaccttccc agtcagcaat agtttgggta atttcatccc taacttcact ttcactagcc
    20101 acctgaatat tgctgtctgc attggccgaa tcactgagga gagccagaac gccgtcacga
    20161 ccaatctctg ccaaacgagc aaaatcagtt gcataagatt cactagccgt ttggtcaaat
    20221 ttgaagtcac ctgtataaac gatgcttcct tccgatgtct tcaagacaat tcccagactc
    20281 tctggaacgg agtaagtcgt agggaagaag gaaaccactg tcccaccaaa atcaatctcc
    20341 gtattctcat caatgacatg gaaatcatta aatttcttaa cggcatcatt tcctttgaca
    20401 aagagctttg ccaactcaat ggtcaactca gacccaaata caggaacttt agcctctgcc
    20461 aagagataag gtagagcacc aatggcatcc gcatgcccgt gggtcaagaa aaccccagca
    20521 atacggtcgc tattttcaaa aaggtaatcc atgtttggaa tcaccacatc gacccctaat
    20581 tgttcatttt caggatattt taaccctaca ttcaaaacaa aaatggactc tccaatttca
    20641 gcaatgtaca tattttttcc attctcacgc acaccaccaa gtgttgttaa actgatatta
    20701 ctcatttttc ctccaaaatc ttagtttatc ttgattatag ggcaactcta ccctcttatt
    20761 ctaaaagttc taatactttc agccgaatct tttcctacca ttataccatt tttttgatga
    20821 ttttcaaaat gaaggtctgt tttcaaaaaa gagttgattt cccaactctt tcctaacttc
    20881 tactcttttt ccatcaaaaa atcataaatt tcttgcaccg tacccagcgc catcatttct
    20941 tggtctttaa cggtttgttt gagattttgg taaatttgac tttctcctat ctcccgcttt
    21001 ggcgcctctt tattgactgt catcacacca tcttttatcg tcacaaagcc tagttcttca
    21061 aatacttgaa tcatcttgac cagcaagatt tgttgaatat taagatatgc agccaaatct
    21121 ttcagcttgt agcgaatatc aaactctggg aactggtaaa tagtcttgta caatttggca
    21181 aactgatctc tagtcccata acctgtcaga taataggcct tgtcaatatc atttttgaaa
    21241 tagacagcag agaaatgctg ttcctgaaaa atggtcttca gctgagtaat actctctgga
    21301 atgtttttta cgacaacagc ttcactagcc gcaagatttg gcagttctcc aggaaaatcc
    21361 aagactggaa caccttctgg caagactgta ttttttccac gaatgttaaa aagttgaaca
    21421 ccttccactc gcgcatccac catcatcaac tggagggcag tttggccatt ccattggttg
    21481 acagacaatt taaccgctaa ctctagattc ttggtttgag aaaactctgt cgcccatctg
    21541 ccttgaccaa aggctaccac ttcaaaactc gcctcaccct tggaaatttt cagctttaga
    21601 tgggcattac ctgcccccat agtacgagca ctttcgacct gaaaattctt gatataaaaa
    21661 ataggtttct gattatccat tccaaaagga gctaaacgtt caaaactttt gaccgtttcc
    21721 aagctaagtg cctccaaatc caactcttca tctaggttta acttattctt tccaccagca
    21781 tctgcacctt tttcacgaac ataatcttcc aaaacctgag ataaatctga gagttgctca
    21841 acttccagcg tcatacccgc tgcacctgca tgacctccaa aggcgatgaa gaggtctcga
    21901 tggggatcca gagcttcaaa aatatcgacc gcttccacac tacgagcact gcccttggca
    21961 cgaccgtctt ctatattaag aacaatgact gtctgtccca attcttccaa taaacgacca
    22021 gccacgattc ctagaacccc aggattccag ccttccttgg ccaagacctg aaccttcttc
    22081 tcaggatcca ccatggtctt ggcttcttca tagatagact gaacgatttc cttgcgctct
    22141 tcgtttttct ggtgaatcat aagggcaatc tcatgcgctt cctcatcatc aaatccagtc
    22201 aacaaatcaa tggcaggatt gggatcatcc aagcggccca aggcattcaa acgaggagca
    22261 atctggaaac caaccgtttc ttctgttact tcgttggcag caatcccagc catgtccagc
    22321 atttcttgca gaccaatgcg ctgggtatga cccaacattt ccagaccata ttgaactaag
    22381 atacgatttt catccgtcag actcaccata tctgcaatag ttccaatagc gaccaaatca
    22441 agcaattcca cttgcacttc ttctaacagg gcacaagcca acttgaaagc aactccacaa
    22501 ccagccaaat atttaaaagg ataatccgca tctggatgtt caggatggac aatagcataa
    22561 gcatctggca gggtttcagg catggaatga tggtctgtca caatgacatc tactcccata
    22621 gactgagcca atgcaatagc ctcatgacca gcaaccccat tgtccaccgt cacaatcaag
    22681 gaaatccctt cttgctcgat aaagtattta taaacactag cattagggcc atagccatcg
    22741 gtaaaacgat ttggcaggta aactcggcac tcagcaccaa gttgttccaa actttccttc
    22801 acaatagaag ccgaagtcat gccatccgca tcgtagtctc cataaacgag aatattttcc
    22861 ctttcttcaa tagcctgacg aatccgctcc actgccttgt ccatatcatg gagcagataa
    22921 gcatcatgta agtcctccaa ggaaggttct aaaaacttct tcagactttc ttggtcctga
    22981 atccctctct caaacaataa ccgagccacc tcaggaccca gtccagcctt cttggctatc
    23041 tttgtaaaat ccgcatcttc tacctgcagg gcaaactgcc attcataagt aggtgttatc
    23101 aaaaagacat ccactctttc taagaattct attgcttcat tataacatga tttagacgtt
    23161 ttctctatcc agattgcttt tttataacat tttatagtat attgaaacta gaatagtaca
    23221 cctctacttc taaaatattg ttagaaatcg atttgactgt cccgatcgat ttgtcctgtt
    23281 cttatttcac tatagtgaat tttttcagat atggtttgac aagaacattc ttttattgta
    23341 gaatcgtgtt ataaaatcta acataaatga gttctctcat ggctttagta gaatttaaaa
    23401 acgtcgaaaa atattacgga gactaccacg cactccgcaa catcaatctc cgttttgaaa
    23461 aaggacaagt tgttgtcctg cttggacctt ctggctctgg gaagtccact cttatccgta
    23521 cgatcaatgg tttagaggct gttgacaaag gaagtctcct agtcaatggg caccaagttg
    23581 ctggtgccag ccagaaagat ttggtacctc ttcgcaagga agtcggcatg gtttttcaac
    23641 attttaacct ttatccacac aaaacagtgt tagaaaacgt gacacttgca cccattaaag
    23701 ttctaggaat tgataaaaaa gaagctgaaa aaaccgccca aaaatatctg gaatttgtaa
    23761 atatgtggga caagaaagat tcctatcccg ccatgctatc tggtggacaa aaacagcgga
    23821 tcgccatcgc tcgtggtctt gctatgcatc cggaactcct cctctttgat gaaccaacat
    23881 ctgctcttga tcctgagact atcggagatg ttctagcagt tatgcagaaa ctggcgcgtg
    23941 atgggatgaa catgatcatc gttacccacg aaatgggctt tgctcgagag gttgcggacc
    24001 gcattatctt tatggccgac ggagaagttt tagtagatac gacagatgtc gataactttt
    24061 ttgacaatcc aagcgaacct cgtgcccaac aattcctcag caaaattatc aaccacgaaa
    24121 gtgacaaagt caaataagga ggcgcctatg aaaaaaaaat tctttttatc agcattattg
    24181 attagccttt tcggccttgt tgctgccaaa ccagtccagg ctaatactag tatcgcagac
    24241 attcaaaaaa gaggcgaact ggttgtcggt gtcaaacaag acgttcccaa ttttggttac
    24301 aaagatccca agaccggtac ttattctggt atcgaaaccg acttggccaa aatggtagct
    24361 gatgaactca aggtcaagat tcactatgtg ccggttacag cacaaacccg cggccccctt
    24421 ctagacaatg aacaggtcga tatggatatc gcgaccttta ccatcacgga cgaacgcaaa
    24481 aaactctaca actttaccag tccctactac acagacgctt ctggattttt ggtcaataaa
    24541 tctgccaaaa tcaaaaagat tgaggaccta aacggcaaaa ccatcggagt cgcccaaggt
    24601 tctatcaccc aacgcctgat tactgaactg ggtaaaaaga aaggtctgaa gtttaaattc
    24661 gtcgaacttg gttcctaccc agaattgatt acttcccttc acgctcatcg tatcgatgcc
    24721 ttttccgttg accgctctat tctatctggc tacactagta aacgcacaga actactagat
    24781 gatagtttca agccatctga ctacggtatt gttaccaaga aatcaaatac agagctcaac
    24841 gactatcttg ataacttggt tactaaatgg agcaaggatg gtagtttgca gaaactttat
    24901 gaccgttaca agctcaaacc atctagtcat accgcagatt aaggaggata ccctatgaca
    24961 gatttatcat cttggacagc ctattttcag gattttggac aatttttcaa tggtttcctc
    25021 tttactcttg ccctagcgat tggatccttt atcctcgcca tggtcttagg aatcttcttt
    25081 ggtgccatgt caaccagtaa acgtccaatt ttacgcattt tagctcgcat cttcgtggaa
    25141 ttttaccaaa acactcccct cttggtgcag tttgttattg ttttttatgg cctacctctt
    25201 atcagtgacc acatcatcat gattccaatt tattggacag ccgttctctg cgtgggactc
    25261 tatcacggcg cttatatcgc tgaggttatt cgttcaggga ttcagtctat tcctagtggt
    25321 cagatggagg ccgccttgtc gcaaggtttt acctatatca gtgccatgcg cttgattatc
    25381 ttgcctcagg ccttccgcat cattctccct ccattgacca accaaattgt taacctcatc
    25441 aagaacacat ctactgtagc tatcatctct ggagtagact tgatgtttgt gactaagtct
    25501 tggtcggctc tcaacggaaa ctatatccca gcctttttag gtgctgctct tctctacttt
    25561 gccctatgct tccctgttgc ccagtttggt cgcaagatgg agcaagccaa taaaaaagcc
    25621 tattcacttt aggaggttac tatggaatct attttagaaa ttttaacccc agataaccta
    25681 gtctttatct ttaaaggatt tggcttgacc ctctatattt ctctgattgc catcatcctc
    25741 tctactatca tcggtaccgt gcttgccgtc atgcgaaatg gaaaaaatcc tatcttacgc
    25801 attatttcca gtatttatat cgagtttgtg cgcaacgttc ccaaccttct ctggattttt
    25861 actatctttt tggtgttcaa aatgaaatcc acaccagcag gtattacagc ctttactctc
    25921 tttacatcag cagccttggc tgagattatt cgaggcggtc tcaatgccgt agacaaggga
    25981 caatacgaag caggaatgtc acaaggcttc acctcagccc aaatcctcta ctacatcatt
    26041 ctcccacaag ccatccgcaa aatgctacca gccatcattt ctcagtttgt taccgtgatt
    26101 aaggatacca gtctcctcta ctctgttatc gccctacaag aactctttgg agccagccaa
    26161 attctcatgg gccgttattt cgaaccagag caggtcttca gtctttacat cctgattgcc
    26221 ctcatctact tcagctttaa cctagcgatt tctagcctgt ctcatatgct agccaaacgt
    26281 tggcaacaag ctgcagaata atactcttcg aaaatctctt caaaccacgt cagcttcacc
    26341 ttgccgtact caagtacagc ctgcggctag cttcctagtt tgctctttga ttttcattga
    26401 gtataaacag ccactctcca gttcaattgg agagtttttt gatgagagta gatatttata
    26461 gacctcaatt tgacaccata cattttctat gataaaatgt aacaaattca tttacaacaa
    26521 atcgaaatct aaatgaaatg gaattttcta tgaaatcagt caaaggacta ctctttatca
    26581 tagctagttt tatcttgact cttttgactt ggatgaacac ttctccccaa ttcatgattc
    26641 caggactagc tttaacaagc ctatctctga cttttatcct agccactcgt ctcccactac
    26701 tagaaagctg gtttcacggt ttggagaagg tctacaccgt ccacaaattc acagcctttc
    26761 tctcaatcat cctactaatc tttcataact ttagtatggg cggtttgtgg ggctctcgct
    26821 tagctgctca gtttggcaat cttgccatct atatctttgc cagcatcatc cttgtcgcct
    26881 atttaggcaa atacatccaa tacgaagctt ggcgatggat tcaccgcctg gtttacctag
    26941 cctatatttt aggactcttt cacatctaca tgataatggg caatcgtctc cttacattta
    27001 atcttctaag ttttcttgtt ggtagctatg cccttttagg cttactagct ggtttttata
    27061 tcatttttct atatcaaaag atttccttcc cctatctagg gaaaattacc catctcaaac
    27121 gcttaaatca cgatactaga gaaattcaaa tccatcttag cagacctttc aactatcaat
    27181 caggacaatt tgcctttcta aagattttcc aagaaggctt tgaaagtgct ccgcatccct
    27241 tttctatctc aggaggtcat ggtcaaactc tttactttac tgttaaaaat tcaggcgacc
    27301 ataccaagaa tatctatgat aatcttcaag ccggcagcaa agtaacccta gacagagctt
    27361 acggacacat gatcatagaa gaaggacgag aaaatcaggt ttggattgct ggaggtattg
    27421 ggatcacccc cttcatctct tacatccgtg aacatcctat tttagataaa caggttcact
    27481 tctactatag cttccgtgga gatgaaaatg cagtctacct agatttactc cgtaactatg
    27541 ctcagaaaaa tcctaatttt gaactccatc taatcgacag tacgaaagac ggctatctta
    27601 attttgaaca aaaaaagtgc ccgaacatgc aaccgtctat atgtgtggtc ctatttctat
    27661 gatgaaggca cttgccaaac agattaagaa acaaaatcca aaaacagagc ttatttacga
    27721 aggattcaag ttcaaataag taatcatact ctcctgggat ttcccaggag agttttttat
    27781 agccaaatga aataagacct gaacgatgga attttggcat tcaaatcaat tgataagaat
    27841 attttatagt ggagtgaaat aggatacgaa caaattgatt aggaaaatca aatgaattta
    27901 tagaaatctt ttagcagtta tgttgtccta ttctagtttc gaaacgctat agaagcagca
    27961 ttgtgctagt ctagattcag tttactatac taaaacgagt agcttgaaat caaaaaaccc
    28021 accctcacag gcaggtttta tctgtattat tcagctagat tatgctttac cttctgaacc
    28081 gaatacgtcg atacgttctt caaccgatgc ttggatagct tttacaccgt cagccaagaa
    28141 tttacgtggg tcgaagagtt ttttcttgtc gtattctgct tcgtttgctt cgtagtcacg
    28201 agcaaattta cgagttgcgt tagcgaatgc gatttggcat tctgtgttaa cgttaacttt
    28261 ggcaacacca agtttgatag ctgcttggat ttgctcatca ggaatacctg atccaccgtg
    28321 caatacgatt gggaatcctg gaagagcttc tgtcaatttt tgcaagtggt caaggtcaag
    28381 accttcccag tttactgggt aagggccgtg gatgttaccg ataccagctg ccaagaagtc
    28441 gataccagtt tcaaccattg ctttagcgtc ttcgattgga gccaattcac ctttaccgat
    28501 gattccgtct tcttcaccac cgatagtacc aacttcagct tctactgaga tacctttagc
    28561 gtgtgctttt tcaacaactt ctttagccaa tttaaggttt tcttcaactg gaaggtgtga
    28621 accgtcaaac atgattgaag tataaccaac ttcgatacac tcaagtgcat cttcgtagtg
    28681 accgtggtca aggtggatag ctactggtac agtgataccc attgattcaa caaggttagc
    28741 gatcaagttg cgagcaactt tgtaaccacc catgtattta gcagcaccca ttgaagtttg
    28801 gatcaaaact ggagcttttt tagcttctgc tgcgcgcaag atagcttgag tccactcaag
    28861 gttgtttgtg ttaaatccac caactgcata accgttgtca cgggctgctt ggacaaattt
    28921 ttctgctgaa acgattgcca ttttatcagg cctcctgtat atttttatgg gtcatcccat
    28981 ttacattgtt cattttatca ctttttgcca aaaaaatcta gtttttcccg cagtttcgat
    29041 tgattttctt ctaactccat ctatgtaaac cctttctctc cctagtcttg gacgactttt
    29101 ggaaaatcta taaagaaggt taaacgattc tcctccatct cgaaacgata agctaatttt
    29161 tcatgttcta atagactctt aaccacaaag agccccatac cagacccctt gaccttgcga
    29221 ctggcattgt cagaaaaaga ctgggctagt ttttcttgtt cctctgagct acagctattt
    29281 tcgataaaaa gttctccttc tctttctcca attcgaacta agccacctgg aacagagtgc
    29341 ttaatggcat tgctgatgag attagaaaga atcaacttca taactgatgg gtttagataa
    29401 gcctgctgat gggtcaaact attgtctatc tggagctctc tttccttggc tagcaaggca
    29461 taatctttga ccagattttg cgtcatctgg aggaggtcaa ttgtttccct atcatctcgc
    29521 aattcctgca cagaagagag ggaaagtatc tgcagaacat ggtgattgag ttcatccaca
    29581 atccccaagg caactcccag atactggtct ctattcttat aacgaccgat attctctctc
    29641 atattttcga ttaggatttt caaactagcc agcggtgttt tcaattcatg agaagctcct
    29701 cgtaggaatt cgaccttcat cttctccagc tggagaatgg cttcattctt ttcatgcaag
    29761 tccgcaataa cagtcaagag atgctggtag aggctattga tttgttcctt gagattgcct
    29821 atctcatcct tagaatccac gcgcaatcgc acttgggaat ccaggtccat catccgacgg
    29881 gtcacccgct tgatttccaa aatcggtgca acaatagtcc gagcgtagat gtaggccacc
    29941 aagagggaaa tcagaaagga ggccagcaag gtatagggaa gaaattggag actgatttgc
    30001 tccgcttcct tttgtaaatc catggaagct agaaactgga gaatcatagt accaccgtct
    30061 tgcgttttca cctcgcgctc ctcaataaag agagaggttg tctggcggtc tgtgtccaga
    30121 ggaagactgt ccttgacttc taacttgtcc tcggtcatct cacctttgac ggtccccttg
    30181 atatcactag tctgggaata caagtctaac acttgctcga tactctgcct atctttccct
    30241 tctagggact gggcaatggc tgttgccttt tgaccaatgg tttcctgacg atgactcaga
    30301 taagtcgaag gaaaaagaaa ataaatagct aaatgaaggc agataaccag aacactaaat
    30361 atcgagaagg tatagataaa tatctttgta aataaacctg ttcgtttcat tttcgctcca
    30421 atttataacc aacattgcgc acagtgagga tacaatccaa gtctagcttt ttccgcaatt
    30481 ccttgatata aacatcaata acacggtcaa agggaacctc atctgtcgct ttccagacgg
    30541 catcgataat ctgagaccga gtcaaggccc ggccttcatt tttcactaga tagtccagaa
    30601 tttccaactc tttggcattg ataggcactt cttgacctgc gaggcttgca ctgtagcttt
    30661 caaagtccac cttggtatcc ttgtaagaaa agattcgtcc tgtatcgtag tagcgcttga
    30721 aaatcgcgtc caccctcact tttaagaggg agagggagaa aggtttttcc agatagccat
    30781 ctgccaaaga ggcaaaggca ctcatcttgt attcctcatc ctgaaaagct gtcaacatca
    30841 agacaggaac ctgactggtt ttacgaatct cagctaggac ttctaagccg ttaagcttgg
    30901 gcatctggat atccagtaaa accagggcca cctcatagct agaaaattgc tccagagctt
    30961 cctgaccgtc cgctgcctca atagtttcat agccacaatc cgtcaaataa tcactgaccc
    31021 cctcacggat catctcttca tcttctacaa ttaaaatttt catactttaa ctgctctcta
    31081 ttttttattt ttcttagaat aaatacctac tctattttct attatagtct cttgctggcc
    31141 ttttgtatgt aagcaactga ccactagata aaacgttgtg aaattccttt ctcataaatt
    31201 ccataacttt agtatattat atttaagcac taaagtacaa agaaagcaac tgaaagcaat
    31261 gattttcacc actgctttca gatttatttt gaattgttaa atagctattc ctatccacta
    31321 ttcttgaata gaaacacaag atgcaatctt tattccagac tcattttttt caaatttatt
    31381 caccatccag caagagctct tttggttgtt ttctaaggag attgcttgaa gcaagcgcca
    31441 taacgagaac cactagaacc aaggcaagga caaaaatgat gataaagtct gatgtctgaa
    31501 tggaaatgtc taggctcgac aaggtcttgc taaagccatc tacttctgca ccgccaccaa
    31561 ggttagaggc ttgagccgcc ttactagcct gtttggcaac acctgaagtc acattggcaa
    31621 ggacagtgtt tccaattgca cgggcagtgt aattagctag gaagtaagca gaaactagag
    31681 cagggatagc aatcaagata gattcggtga tgaattgacc caagatactt gcctgcttga
    31741 gaccaataga gaggaggatt cccacttcct tgcgacgggc attgatccaa agactgagca
    31801 agagggcaag gagaaggact gagaagctca agctacccca gaagaggagg ttggccatct
    31861 tgtacatacc agagatagat tgctcaagag ctgggtagtt agaggagctc ttgacgagtg
    31921 tgtagctctt ccagttgata ccactgatgc cattcaactc tttcataaca tcatccaagt
    31981 tcttgtctgc tgttacaaag aaggttgcgt ccccataaat ggctgtgtct tctgtgtatc
    32041 cataaagttt tgcagcagtg tgaatgtctg taatagctgt gttttcgtaa agttcttgtg
    32101 agtaggttac tgctgactta ttatgaccat caaagagtcc cttgattgtc acttcaactg
    32161 tttccttggc tcctttttca ttatctgcat cgtagatatt agagtccagt ttaaccttgt
    32221 cccctacttt ccagccgtgt ttggctgcca agtccttgtg caagaggatt ttatccttgt
    32281 cgtcgttggt taagtgctct ccttcgacta gtttataaga accagagaca aacttgtctt
    32341 ctttagagga gtcattgaca cctgtaatca tcaagctact tccaaaacgt ttggcacgat
    32401 cagcagtgag attcttcttg gtttctggcg tttcaatcag gtcatatcca gtcaaatctc
    32461 cgatagcgtt gatacgtttg acataagact caatggcctt gttttcggtg atttttttga
    32521 tgtcttcacc cttgatattc ccagcaccac gaggcgttcc ttggttgacg cgacgattga
    32581 tttgcatgga gaagctattg gtgatatttt taaaggtctc ctgagaagcc ttggcagtag
    32641 ctcccttgat tgacaagccg accaaactca agctcgccat aaggagaata atcaggaaga
    32701 tgacaatcga tttgaaaaac ttccttgtaa cataggcaaa tgcgttgtgt aacatagatt
    32761 ccctttctag attttgtttt aatcattcta tcaaaataag ctcaaattat ttactagtat
    32821 tgcgcgtttc agtcagtttc ttatccttta attcaagtgt aatatctgac gcttgtgcca
    32881 cttctttact gtgagttacg acaatcacac atttacctgt tttctgggca agtgatttga
    32941 gtagttcgac aatatctcca gcagttttag gatccagatt tcctgttggc tcatcagcta
    33001 gaataactgg agcttctgag accaaactgc gagcaatggc aacacgttgc tgttgaccac
    33061 ctgataactg gagaacattc cgcttaatct ggctttcatc caaaccaagc tcaagaagtg
    33121 tattcttgct tgcctttttg ttgaccaatt ggatattttc cagcggagaa agataatcta
    33181 tcaagttata attttgaaag accagggaaa tatggtgcat gcgatggtaa gaatagccct
    33241 tcttacgaat atcctctcct tgaaaaagga tagaaccttc aacaggacta tctagagcag
    33301 caagtaggga caagagtgtg gattttcctg ctcctgactc cccaataata ctgtaaaatt
    33361 ttccgggttc aaaattataa ttgatctgat ataggactgc ttcagcagta ttcttataac
    33421 ggtaggtaac atcttgtaat tgtaataaag tcatgatttc tccttcttaa ctaatagatg
    33481 ataaaatttc tttcggtgat tttctaaata agaataggaa acaaagggct acagataagc
    33541 aactaagcag aactagaaaa acataggatt ctgcaaaaga taagatgcta gttgataaac
    33601 tgcttgcttt ggctagtgta tcttgtaagc ttacctgatc tccacttgct agtagagttt
    33661 ggagtaggta agttgtgatt ccgtttcctg caacaaatgc tggaagcaaa gctccaagag
    33721 ataccaaaac tacctctaaa cagaattgta ggaagatcga gctcttgcct tttccaagtg
    33781 caagtaaaat ccccacttca tagacccgtt ctctcaacca gagagacaaa accagaatta
    33841 aggctccagc tcctgctatc aacatcccat aaaggaagat ggtcaggaag gtttggaaag
    33901 ttgcaactga gtctttgatt tgttcaaaag ccttgttttc cttttcgact tggtagcctt
    33961 gattttccaa ggccaagttt tctacctgct tcatgagtcc gtccatttcc ttaggatttt
    34021 ctacatagaa gcgtgctgca ctgacttgag cttcactatt gcccaaaagg gtttggctac
    34081 tttcataatc tgtaaagact tgattttcac tgaagtcaga agacaagcct gtgaatttct
    34141 cttgtttttt accagaaaag atgccgataa tctcaaactc tactgtttgt ccttttccag
    34201 attcagactg accagcatcc aagccaatct tgtcatgaag tgaaagaccg ttcttcttag
    34261 ccaattcttc gtggataagg attttcttgg aatccccttt ttgaaggtgt cgcccttctt
    34321 ttagattgaa agccgaactg gtaaaggtta catccttgga tgaatcctca agagccgtta
    34381 agctaaccaa gttattgtct gcagctgata aatcatcacg ctccacgctc tgctcgccag
    34441 tcactgcttc cttgtctttt agttttgcga ccgtctcaag ttcaggagag acattttcca
    34501 gccccttaat cttgcttaca gatgctaggt ctgacaactt gaatgtctga ccattctcta
    34561 tcttcttaat agaaaaagat gtattgagtg atttataaag attgctttct actgttttgt
    34621 tggacttcat cagagtcaaa caggctgaaa ttccggccaa taagaccaat aaaatcagaa
    34681 ataaaataaa acttctcagt cgctttctgc tgacataagc ccaagatctt tggattggat
    34741 tcatttgtca cctccatatt tgtaagacta ttataaaacc caaatatgaa atgtttatga
    34801 aatacgaaaa aaaaaa
//
LOCUS       DAVKBC010000018        34381 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVKBC010000018 DAVKBC010000000
VERSION     DAVKBC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.018"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            575..1027
                     /locus_tag="VWX64_001025"
     CDS             575..1027
                     /locus_tag="VWX64_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9190506.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1046..2383
                     /locus_tag="VWX64_001026"
     CDS             1046..2383
                     /locus_tag="VWX64_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU9190507.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSIQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2462..3346
                     /locus_tag="VWX64_001027"
     CDS             2462..3346
                     /locus_tag="VWX64_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9190508.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3346..4179
                     /locus_tag="VWX64_001028"
     CDS             3346..4179
                     /locus_tag="VWX64_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9190509.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4197..6290
                     /gene="nanB"
                     /locus_tag="VWX64_001029"
     CDS             4197..6290
                     /gene="nanB"
                     /locus_tag="VWX64_001029"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU9190510.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFENATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6303..7406
                     /locus_tag="VWX64_001030"
     CDS             6303..7406
                     /locus_tag="VWX64_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9190511.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7580..8278
                     /locus_tag="VWX64_001031"
     CDS             7580..8278
                     /locus_tag="VWX64_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU9190512.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8297..9814
                     /locus_tag="VWX64_001032"
     CDS             8297..9814
                     /locus_tag="VWX64_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9190513.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9939..11267
                     /locus_tag="VWX64_001033"
     CDS             9939..11267
                     /locus_tag="VWX64_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9190514.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11519..12385
                     /locus_tag="VWX64_001034"
     CDS             11519..12385
                     /locus_tag="VWX64_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9190515.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12401..13240
                     /locus_tag="VWX64_001035"
     CDS             12401..13240
                     /locus_tag="VWX64_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9190516.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13513..13965
                     /locus_tag="VWX64_001036"
     CDS             13513..13965
                     /locus_tag="VWX64_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9190517.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            14062..14406
                     /locus_tag="VWX64_001037"
     CDS             14062..14406
                     /locus_tag="VWX64_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190518.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIIRGIVTGLIGGHIKLGAY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGRILQIAVNVADVYGNFAYNIAAAWDA
                     HDKIPNNGRINF"
     gene            14691..15335
                     /locus_tag="VWX64_001038"
     CDS             14691..15335
                     /locus_tag="VWX64_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9190519.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15504..16421
                     /locus_tag="VWX64_001039"
     CDS             15504..16421
                     /locus_tag="VWX64_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU9190520.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16439..17323
                     /locus_tag="VWX64_001040"
     CDS             16439..17323
                     /locus_tag="VWX64_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9190521.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASMTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17339..18190)
                     /locus_tag="VWX64_001041"
     CDS             complement(17339..18190)
                     /locus_tag="VWX64_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU9190522.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18390..20447
                     /gene="pbp2b"
                     /locus_tag="VWX64_001042"
     CDS             18390..20447
                     /gene="pbp2b"
                     /locus_tag="VWX64_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU9190523.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20458..21054
                     /gene="recR"
                     /locus_tag="VWX64_001043"
     CDS             20458..21054
                     /gene="recR"
                     /locus_tag="VWX64_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU9190524.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21230..22273
                     /locus_tag="VWX64_001044"
     CDS             21230..22273
                     /locus_tag="VWX64_001044"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU9190525.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISRSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22357..23730
                     /locus_tag="VWX64_001045"
     CDS             22357..23730
                     /locus_tag="VWX64_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU9190526.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTTYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLVP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            23717..24328
                     /locus_tag="VWX64_001046"
     CDS             23717..24328
                     /locus_tag="VWX64_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9190527.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQMEQYLD"
     gene            24419..25123
                     /locus_tag="VWX64_001047"
     CDS             24419..25123
                     /locus_tag="VWX64_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU9190528.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTIYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGIFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25342..26715
                     /gene="ftsA"
                     /locus_tag="VWX64_001048"
     CDS             25342..26715
                     /gene="ftsA"
                     /locus_tag="VWX64_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU9190529.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRTGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26732..27991
                     /gene="ftsZ"
                     /locus_tag="VWX64_001049"
     CDS             26732..27991
                     /gene="ftsZ"
                     /locus_tag="VWX64_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU9190530.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27996..28667
                     /locus_tag="VWX64_001050"
     CDS             27996..28667
                     /locus_tag="VWX64_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU9190531.1"
                     /translation="MNVKENTELVFREVAEASLSANRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELMEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28677..29216
                     /locus_tag="VWX64_001051"
     CDS             28677..29216
                     /locus_tag="VWX64_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU9190532.1"
                     /translation="MSLKDRFDRFIDYFTENEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29216..29479
                     /locus_tag="VWX64_001052"
     CDS             29216..29479
                     /locus_tag="VWX64_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU9190533.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSIWVAIVLVRFLGENLVRFLAMIG"
     gene            29476..30261
                     /locus_tag="VWX64_001053"
     CDS             29476..30261
                     /locus_tag="VWX64_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU9190534.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30270..31004
                     /gene="divIVA"
                     /locus_tag="VWX64_001054"
     CDS             30270..31004
                     /gene="divIVA"
                     /locus_tag="VWX64_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001123193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU9190535.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVHDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DLLRPTATYLQTSDEAFKEVVSKVLGEPIPAPIEEEPIDMTRQFSQAEMAELQARIEV
                     ADKELAEFEAQIKQEVEAPTCSESSG"
     gene            31404..34196
                     /locus_tag="VWX64_001055"
     CDS             31404..34196
                     /locus_tag="VWX64_001055"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU9190536.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10579 a         6091 c         7474 g        10237 t
ORIGIN      
        1 ctaattgaaa acggtaacaa aactaattta gagaatgaaa tatagagtat ttctctctta
       61 aaagtttttg gtgaaacgag atgtagaaag gagatttagc caaagagtct attagtgcta
      121 gaataataga ttagaattat tttagaaaaa cgaagtgagc agcttataaa ttcaagtccc
      181 caaatagatt catactagta tcttttgcaa aaaataaagg gcgacttcct tcatgaatat
      241 caatttcatc tataaggaag gtagctaatt gaactaactt atttattctg tttgtcgcta
      301 gaaaaatcag acctccttgt gaagattgag gagatactta atgaaaatca aagaagaaac
      361 tagcaagcta gtagcagatt gcccaaaaca ccgctttgag gttgtagata agactgacct
      421 atataatcca aggtgaagcg actgtggttt gaagagattt tcaaagagta taggctagag
      481 agtagtgttt ttatgtcctt ctagtagaaa atgctagaca gaagaatggg gaacttggat
      541 aggaaaaata gattgagaaa ggaggttaga agagatgatt attacaaaaa ttagccgttt
      601 aggaacttat gtgggagtaa atccacattt tgcaacatta atagattttc tagaaaaaac
      661 aggactagaa aatttaacag aaggttcgat tgctatcgat ggtaatcgat tgtttgggaa
      721 ttgctttact tatctagcag atggtcaagc aggggctttc tttgaaacac accaaaaata
      781 tttggatatt catttagttt tggaaaacga agaagccatg gctgttacat cgccggaaaa
      841 tgtaagcgtt acccaagaat atgatgaaga gaaagatatt gaattataca cagggaaagt
      901 ggaacagttg gttcatttga gagctggtga atgcctcatc acttttccag aagatttaca
      961 tcaacccaag gttcgtataa atgatgaacc tgtgaaaaaa gttgtcttta aagttgcgat
     1021 ttcttaatgt agaaagagaa gaacgatgaa aaaaatgaga aagtttttat gtctagctgg
     1081 aattgcgcta gcggctgttg ccttggtagc ttgttcagga aaaaaagaag ctacaactag
     1141 tactgaacca ccaacagaat tatctggtga gattacaatg tggcactcct ttactcaagg
     1201 accccgttta gaaagtattc aaaaatcagc agatgctttc atgcaaaagc atccaaaaac
     1261 gaaaatcaag attgaaacat tttcttggaa tgacttctat actaaatgga ctacaggttt
     1321 agcaaatgga aatgtgccag atatcagtac agctcttcct aaccaagtaa tggaaatggt
     1381 caactcagat gctttggtgc cgctaaatga ttctatcaag cgtattggac aagataaatt
     1441 taacgaaact gccttaaatg aggcaaaaat cggagatgat tactactctg ttcctcttta
     1501 ttcacatgca caagtcatgt gggttagaac agatttgtta aaagaacata atattgaggt
     1561 tcctaaaact tgggatcaac tctatgaagc ttctaaaaaa ttgaaagaag ctggagttta
     1621 tggcttgtct gttccgtttg gaacaaatga cttaatggca acacgtttct tgaacttcta
     1681 cgtacgtagt ggtggaggaa gcctcttaac aaaagatctt aaagcagact tgacaagcca
     1741 acttgctcaa gatggtatta aatactgggt taaattgtat aaagaaatct cacctcaaga
     1801 ttctttgaat tttaatgtcc ttcaacaagc taccttgttc tatcaaggaa aaacagcatt
     1861 tgactttaac tctggcttcc atatcggagg aattaatgcc aacagtcctc aattgattga
     1921 ttcgattgat gcttatccta ttccaaaaat caaagagtct gataaagacc aaggaattga
     1981 aacctcaaac attccaatgg ttgtttggaa aaattcaaaa catccagaag ttgctaaagc
     2041 attcttagaa gcactttata atgaagaaga ctacgttaaa ttccttgatt caactccagt
     2101 aggtatgttg ccaactatta aggggattag cgattctgca gcctataaag aaaatgaaac
     2161 tcgtaagaag tttaaacatg ctgaagaagt aattactgaa gctgttaaaa aaggtactgc
     2221 tattggttat gaaaatggac caagtataca agctggtatg ttgactaacc aacacattat
     2281 tgaacaaatg ttccaagata tcattacaaa tggaacagat cctatgaaag cagcaaaaga
     2341 agcagaaaaa caattaaacg atttatttga ggctgttcag tagatgtaaa agactagaaa
     2401 ataggtgggc tagtgagctg aaaagctcta gcccaatttt gtaaaagaag ggagaaggag
     2461 aatggttaaa gaacgtaatt taactcgctg gatatttgtt ttgccagcta tgattatcgt
     2521 aggattactc tttgtttatc cgtttttctc gagtattttt tatagcttta ccaataagca
     2581 tttgattatg cctaattata aatttgttgg tttggctaac tataaagctg tgctatcaga
     2641 tcccaacttc tttaatgcgt tctttaattc aattaagtgg accattttct cattagttgg
     2701 tcaagtttta gtagggtttg tattggcttt agctcttcac agagtacgcc acttcaagaa
     2761 attatatagg accttattga ttgttccttg ggcatttcct accatcgtta ttgccttctc
     2821 ttggcagtgg attctaaacg gggtttatgg ctacttacct aatctaatcg taaaattagg
     2881 tttaatggaa catacacctg catttttgac agatagtaca tgggcattcc tatgtttggt
     2941 gtttatcaac atttggtttg gagcaccaat gattatggtt aatgtgcttt cagctttgca
     3001 aacagtacca gaagaacaat ttgaggctgc taagatagat ggtgcttcaa gttggcaggt
     3061 gttcaagttt atcgtctttc cacatattaa agtggttgta ggacttctag ttgttttgag
     3121 aactgtatgg atctttaata actttgacat tatctacctc attactggtg gtggaccagc
     3181 caatgctaca acgacgcttc caatttttgc ttacaacctg ggctggggaa ctaaattgtt
     3241 gggtcgtgct tcagcagtta cagtattgct ctttatcttc ttggtggcga tttgctttat
     3301 ctactttgct atcatcagta agtgggaaaa ggagggtaga aaataatgaa gaagaaatcc
     3361 agtatttatt tagatattct ctcacatgta cttttagttg gtgcgaccat cgttgcagtt
     3421 ttcccattgg tatggattat catatcttct gtcaaaggga aaggggaatt aactcagtat
     3481 ccaacacgat tttggcctga acagtttaca ttagattatt tcactcatgt tatcaacgat
     3541 ttgcacttca ttgataacat tcgaaacagt ttaatcattg ccttggctac aacccttatt
     3601 gcgattatta tttctgctat ggcagcctat ggtattgttc gattctttcc taaattggga
     3661 gcaatcatgt cgagactact cgtcattacc tacattttcc caccaatttt gttagcaatt
     3721 ccctattcaa ttgccattgc taaagttggg ttaacaaata gtttatttgg cttgatgatg
     3781 gtttatctat cttttagtgt tccatatgca gtttggctct tagttggatt tttccaaaca
     3841 gttccaattg gaattgaaga agcggctaga attgatggtg caaataaatt tgttacgttt
     3901 tataaagttg tgctaccgat tgtagcacca ggtattgtag caacagctat ttatacattt
     3961 atcaatgctt ggaatgaatt cctgtatgcc ttgattttga ttaacaatac aggaaagatg
     4021 acagtagcag tagcccttcg ttcacttaat ggttcagaaa tactagactg gggagatatg
     4081 atggcagcgt ctgttattgt agttcttcca tcaattattt tcttctctat catccaaaat
     4141 aagattgcaa gtggattatc agaaggatct gtgaagtaga cgaaagaagg aaaaaaatga
     4201 ataaaagagg tctttattca aaactaggaa tttctgttgt aggcattagt cttttaatgg
     4261 gagtccccac tttgattcat gcgaatgaat taaactatgg tcaactgtcc atatctccta
     4321 tttttcaagg aggctcatat caactgaaca ataagagtat agatatcagc cctttgttat
     4381 tagataaatt gtctggagag agtcagacag tagtaatgaa atttaaagca gataaaccaa
     4441 actctcttca agctttgttt ggcctatcta atagtaaagc aggctttaaa aataattact
     4501 tttcaatttt catgagagat tctggtgaga taggtgtaga aataagagac gcccaaaagg
     4561 gaataaatta tttattttct agaccagctt cattatgggg aaagcataaa ggacaggcag
     4621 ttgaaaatac actagtattt gtatctgatt ctaaagataa aacatacaca atgtatgtta
     4681 atggaataga agtgttctct gaaacagttg atacattttt gccaatttca aatataaatg
     4741 gtatagataa ggcaacacta ggagctgtta atcgtgaagg taaggaacat tacctcgcaa
     4801 aaggaagtat tgatgaaatc agtctattta acaaagcaat tagtgatcag gaagtttcaa
     4861 atattccctt gtcaaatcca tttcagttaa ttttccaatc aggagattct actcaagcta
     4921 actattttag aataccgaca ctatatacat taagtagtgg aagagttcta tcaagtattg
     4981 atgcacgtta tggtgggact catgattcta aaagtaagat taatattgcc acttcttata
     5041 gtgatgataa tgggaaaacg tggagtgagc caatttttgc tatgaagttt aatgactatg
     5101 aggagcagtt agtttactgg ccacgagata ataaattaaa gaatagtcaa attagtggaa
     5161 gtgcttcatt catagattca tccattgttg aagataaaaa atctgggaaa acgatattac
     5221 tagctgatgt tatgcctgcg ggtattggaa ataataatgc aaataaagcc gactcaggtt
     5281 ttaaagaaat aaatggtcat tattatttaa aactaaagaa gaatggagat aacgatttcc
     5341 gttatacagt tagagaaaat ggtgtcgttt atgatgaaac aactaataaa cctacaaatt
     5401 atactataaa tgataagtat gaagttttgg agggaggaaa gtctttaaca gtcgaacaat
     5461 attcggttga ttttgatagt ggctctttaa gagaaaaaca taatggaaaa caggtcccta
     5521 tgaatgtttt ctacaaagat tcgttattta aagtgactcc tactaattat atagcaatga
     5581 caactagtca gaatagagga gagagttggg aacaatttaa gttgttgcct ccgttcttag
     5641 gagaaaaaca taatggaact tacttatgtc ccggacaagg tttagcatta aaatcaagta
     5701 acagattgat ttttgcaaca tatactagtg gagaactaac ctatctcatt tctgatgata
     5761 gtggtcaaac atggaagaaa tcctcagctt caattccgtt tgaaaatgca acagcagaag
     5821 cacaaatggt tgaactgaga gatggtgtga ttagaacatt ctttagaacc actacaggta
     5881 agatagctta tatgactagt agagattctg gagaaacatg gtcggaagtt tcgtatattg
     5941 atggaatcca acaaacttca tatggcacac aagtatctgc aattaaatac tctcaattaa
     6001 ttgatggaaa agaagcagtc attttgagta caccaaattc tagaagtggc cgtaagggag
     6061 gtcaattagt tgtcggttta gtcaataaag aagatgatag tattgattgg aaataccact
     6121 atgatattga tttgccttcg tatggttatg cctattctgc gattacagaa ttgccaaatc
     6181 atcacatagg tgtactgttt gaaaaatatg attcgtggtc gagaaatgaa ttgcatttaa
     6241 gcaatgtagt tcagtatata gatttggaaa ttaatgattt aacaaaataa aggagaaaaa
     6301 acatggttaa atacggtgtt gttggagcag ggtattttgg agctgaattg gctcgctaca
     6361 tgcaaaagaa tgatggagca gagattactc ttctctatga tccagataat gcagaggcga
     6421 ttgcagaaga attgggagca aaagtagcaa gttccttaga tgagttggtt tctagcgatg
     6481 aagtagattg tgttatcgtc gcaactccaa ataatcttca taaggaaccg gttattaagg
     6541 ctgcacagca tggtaaaaat gttttctgtg aaaaaccaat tgcgctttct tatcaagatt
     6601 gtcgcgagat ggtagatgcg tgtaaagaaa acaatgtaac ctttatggca ggacatatta
     6661 tgaatttctt taatggtgtt catcatgcaa aagaactcat taatcaagga gttatcggag
     6721 acgttctata ttgtcataca gctcgtaatg gttgggaaga acaacaaccg tcagtatcat
     6781 ggaaaaaaat tcgtgaaaaa tcaggtggtc acttgtatca ccacatccat gaattggatt
     6841 gcgttcaatt ccttatgggg ggcatgcctg aaactgtaac catgacaggt ggaaatgtgg
     6901 cccatgaagg tgaacatttc ggtgatgaag atgatatgat ttttgtcaat atggaatttt
     6961 ctaataagcg ttttgctttg ttagaatggg gttcagctta tcgttggggt gaacattatg
     7021 tcttaatcca aggaagcaaa ggtgccatcc gcttagactt attcaactgt aaaggaactc
     7081 ttaagctaga tgggcaagaa agctatttct tgattcacga atcgcaagaa gaagatgatg
     7141 atcggactcg tatctatcat agtacagaga tggatggagc aattgcttat ggtaaaccag
     7201 gtaaacgtac tccattatgg ctatcatctg tcattgataa agaaatgcgc tatctgcatg
     7261 agattatgga aggagctcca gtatcagaag aatttgcaaa acttttgaca ggtgaagctg
     7321 ccctagaagc aattgctact gcagatgctt gtacccagtc tatgtttgaa gatcgcaaag
     7381 taaaattgtc agaaattgta aaataaattt tggtattctc ctatttatag gtcgacttgc
     7441 tcctctgaaa gtacttttag aggagctgtt tgactttgct agtttttgaa actgaaatct
     7501 attatactac aaactattga aagcgtttta attttaaggt ataataatct catagaaata
     7561 aagaaaagga ggaaagagga tgccacagat tagcaaagaa gccttgattg agcaaatcaa
     7621 agatggaatc atcgtttctt gtcaggctct tcctcatgaa ccgctttata cagaagcggg
     7681 aggggtgatt cccttgctgg tcaaagcggc tgagcaaggt ggagcagtcg gtatccgagc
     7741 aaacagtgtt cgcgatatca aggaaattaa ggaggtcact aaacttccaa tcattgggat
     7801 tatcaaacgt gattatccac ctcaggaacc cttcatcacg gctactatga aagaagttga
     7861 tgaattggca gaactggaca tcgaggtgat tgctctggat tgtaccaagc gtgaacgcta
     7921 cgatggtttg gaaattcaag agttcattcg tcaggttaag gagaaatatc ctaatcagct
     7981 tttgatggct gatactagta tcttcgaaga agggctagca gctgtagaag caggaattga
     8041 ctttgtcgga acaaccttat caggctacac atcctacagt ccaaaagtag acggtccaga
     8101 ttttgaattg attaagaaac tctgtgatgc cggtgtagat gtcattgcag aaggaaaaat
     8161 tcatacacca gaacaagcca aacaaatcct tgaatatgga gtgcgaggca tcgttgttgg
     8221 tggcgccatt actagaccaa aagagattac agaacgcttc gttgctagtc ttaaataaga
     8281 tgtgaggggg agttttatgt ttaaagtttt acaaaaagtt ggaaaagctt ttatgttacc
     8341 tatagctata cttcctgcag caggtctact tttggggatt ggtggtgcac tttcaaaccc
     8401 aaccacgata gcaacttatc caatactaga caatagtatt tttcaatcaa tattccaagt
     8461 aatgagctct gcaggagagg ttgtattcag taatttgtca ctacttctct gtgtgggatt
     8521 atgtattggc ttagcgaaac gagataaagg aaccgctgcg ttagcaggag taactggtta
     8581 cttagttatg actgcaacga tcaaagcttt agtaaaactt tttatggcag aaggatctgc
     8641 aattgatact ggagttattg gagcattagt tgtcggaata gttgccgtat atttgcacaa
     8701 ccgatataac aatattcaat taccttccgc tttaggattc tttggaggtt cacgcttcgt
     8761 tcctattgtt acatcgttct cttctatctt gattggcttt gtcttctttg ttatttggcc
     8821 acctttccaa caacttcttg tttctacagg tggatatatt tctcaggcgg gtccaattgg
     8881 aacttttcta tatggatttt taatgagact ttctggagca gtaggcttac atcatataat
     8941 ttaccctatg ttttggtata ctgaacttgg tggtgttgaa actgttgcag gacaaacagt
     9001 ggttggagct caaaaaatat tttttgctca attagccgat ctggcccatt ctggattatt
     9061 tacagaagga acaaggtttt ttgcaggtcg tttctcaaca atgatgttcg gtttaccggc
     9121 tgcctgttta gcgatgtacc atagtgttcc taaaaatcgt cgtaaaaaat acgcgggttt
     9181 gttttttgga gttgctttaa catcttttat taccggtatt acagaaccaa ttgaatttat
     9241 gtttctattc gtcagtccgg ttctatatgt tgttcacgca ttccttgatg gtgttagctt
     9301 ctttattgca gacgtcttaa atatttcaat aggaaacaca ttttcaggag gtgtaatcga
     9361 tttcacttta tttggaattt tgcaggggaa cgctaagacg aattgggttc ttcagattcc
     9421 atttggactt atttggagtg ttttgtatta tattattttt agatggttca ttactcaatt
     9481 caacgttcta acgccaggac gaggagaaga agtagattct aaagaaattt ctgaatccgc
     9541 agattcaact tcaaatactg cagattattt aaaacaggat agcctacaaa ttatcagagc
     9601 cttgggtgga tcaaataata tagaagatgt agatgcttgt gtgacacgtt tacgtgtagc
     9661 tgtaaaagaa gttaatcaag ttgataaagc acttttaaaa caaattggtg cagttgatgt
     9721 cttagaagtg aagggtggca ttcaagcaat ctatggagca aaagcaatct tatataaaaa
     9781 tagtattaat gaaattttag gtgtagatga ttaagtactt actgacttaa taaaaaacag
     9841 aggagagtga tggatgagta ggatgaaatg aaatcgcata caagaaataa agaactcatt
     9901 atccaagttg gatacgctta ttacatagga gaatacaaat gaaatttaga aaattagctt
     9961 gtacagtact tgcgggtgct gcggttcttg gtcttgctgc ttgtggcaat tctggcggaa
    10021 gtaaagatgc tgccaaatca ggtggtgacg gtgccaaaac agaaatcact tggtgggcat
    10081 tcccagtatt tacccaagaa aaaactggtg acggtgttgg aacttatgaa aaatcaatca
    10141 tcgaagcgtt tgaaaaagca aacccagata taaaagtgaa attggaaacc atcgacttca
    10201 agtcaggtcc tgaaaaaatc acaacagcca tcgaagcagg aacagctcca gacgtactct
    10261 ttgatgcacc aggacgtatc atccaatacg gtaaaaacgg taaattggct gagttgaatg
    10321 acctcttcac agatgaattt gttaaagatg tcaacaatga aaacatcgta caagcaagta
    10381 aagctggaga caaggcttat atgtatccga ttagttctgc cccattctac atggcaatga
    10441 acaagaaaat gttagaagat gctggagtag caaaccttgt aaaagaaggt tggacaactg
    10501 atgattttga aaaagtattg aaagcactta aagacaaggg ttacacacca ggttcattgt
    10561 tcagttctgg tcaaggggga gaccaaggaa cacgtgcctt tatctctaac ctttatagcg
    10621 gttctgtaac agatgaaaaa gttagcaaat atacaactga tgatcctaaa ttcgtcaaag
    10681 gtcttgaaaa agcaactagc tggattaaag acaatttgat caataatggt tcacaatttg
    10741 acggtggggc agatatccaa aactttgcca acggtcaaac atcttacaca atcctttggg
    10801 caccagctca aaatggtatc caagctaaac ttttagaagc aagtaaggta gaagtggtag
    10861 aagtaccatt cccatcagac gaaggtaagc cagctcttga atatcttgta aacgggtttg
    10921 cagtattcaa caataaagac gacaagaaag tcgctgcatc taagaaattc atccagttta
    10981 tcgcagatga caaagagtgg ggacctaaag acgtagttcg tacaggtgct ttcccagtcc
    11041 gtacttcatt tggaaaactt tatgaagaca aacgcatgga aacaatcagc ggctggactc
    11101 aatactactc accatactac aacactattg atggatttgc tgaaatgaga acactttggt
    11161 tcccaatgtt gcaatctgta tcaaatggtg acgaaaaacc agcagatgct ttgaaagcct
    11221 tcactgaaaa agcgaacgaa acaatcaaaa aagctatgaa acaatagtcc ttagttattc
    11281 tataaaaagt agttttttaa agaacctaag agtgtatacc cccttttccc tctacacaga
    11341 tagtgtaaga aaagggggct tttgtttaaa atgtaagaaa ctgtcacgaa attaaaatga
    11401 agttcttaca taagcgaacc ataaaaaatt tcattttgat tttaaaacag ttcaagaaag
    11461 tcaaaaaatt attctatttg aaagagaggt gccgactgtg aaagtcaata aaatccgtat
    11521 gcgggaaaca gtgatttcct atgctttcct agcaccagta ttattcttct ttgtcatctt
    11581 tgtgttggct ccgatggtga tgggcttcat tacaagtttc tttaactact caatgactaa
    11641 atttgagttt gtaggcttgg ataactatat ccgtatgttt aaagatcctg tctttacaaa
    11701 atctctgatt aacacagtta ttttggttat tggatctgta ccagttgttg ttctattctc
    11761 actctttgta gcatctcaga cctatcatca aaatgtcatt gccagatcct tctaccgttt
    11821 cgtcttcttc cttcctgttg taacgggtag tgttgccgtg acagttgttt ggaaatggat
    11881 ttatgaccca ctatcaggga ttctaaactt tgtccttaag tcaagccaca tcatcagcca
    11941 aaacatttct tggttgggag ataaaaactg ggcattgatg gcgattatga ttattctctt
    12001 gaccacttca gttggtcagc ccatcatcct ttatatcgct gccatgggga atattgacaa
    12061 ttcactggtt gaagcggcgc gtgttgatgg tgcaactgag tttcaagttt tttggaagat
    12121 taaatggcca agccttcttc caacaactct ttatattgca atcatcacaa caattaactc
    12181 attccagtgt ttcgccttga ttcagctttt gacatctggt ggtccaaact actcaacaag
    12241 taccttgatg tactaccttt acgaaaaagc cttccaattg acagaatacg gctatgccaa
    12301 cacaattggt gtcttcttgg cagtcatgat tgctatcgta agctttgttc aatttaaagt
    12361 acttggaaac gacgtagaat actaaagaaa ggagacagct atgcaatcta cagaaaaaaa
    12421 accattaaca gcctttactg ttatttcaac aatcattttg ctcttgttga ctgtgctgtt
    12481 catctttcca ttctactgga ttttgacagg ggcattcaaa tcacaacctg atacaattgt
    12541 tattcctcct cagtggttcc ctaaaatgcc aaccatggaa aacttccaac aactcatggt
    12601 gcagaaccct gccttgcaat ggatgtggaa ctcagtattt atctcattgg taaccatgtt
    12661 cttagtttgt gcaacctcat ctctagcagg ttatgtattg gctaaaaaac gtttctatgg
    12721 tcaacgcatt ctatttgcta tctttatcgc tgctatggcg cttccaaaac aagttgtcct
    12781 tgtaccattg gtacgtatcg tcaacttcat gggaatccac gatactctct gggcagttat
    12841 cttgcctttg attggatggc cattcggtgt cttcctcatg aaacagttca gtgaaaatat
    12901 ccctacagag ttgcttgaat cagctaaaat cgacggttgt ggtgagattc gtaccttctg
    12961 gagtgtagcc ttcccgattg tgaaaccagg gtttgcagcc cttgcaatct ttaccttcat
    13021 caatacttgg aatgactact tcatgcagtt ggtaatgttg acttcacgta acaatttgac
    13081 catctcactt ggggttgcga ccatgcaggc tgaaatggca accaactatg gtttgattat
    13141 ggcaggagct gcccttgctg ctgttccaat cgtcacagtc ttcctagtct tccaaaaatc
    13201 cttcacacag ggtattacta tgggagcggt caaaggataa tactctgcga aaatcgaatg
    13261 caaactacgt cagcttcacc ttgccatact taagtattgc ctgtggttag cttcctagtt
    13321 tgttcttcaa ttttcattga gtataggaaa atcaatctat caagatacag aagtatattt
    13381 tatagattta gagaatatag aagttataag tgtctacaaa atggagggta tgcagttact
    13441 ttatgaagtt ttgtcagaca cttataaact taagaatggt tttagttaac tatcagaaac
    13501 gaaggaaaga gtatgatttt tgacgatttg aaaaacatca ccttttacaa agggattcat
    13561 cccaatttag acaaggctat cgactatctc taccaacatc gtaaagattc attcgaatta
    13621 ggaaagtatg agattgatgg agataaagtc tttctagttg ttcaggaaaa tgtcctcaat
    13681 caagttgaga ataatcaatt tgaacaccat aagaactatg cagatttgca tttgctgata
    13741 gaagggcatg aatattcgag ctacggttca cgtatcaaag acgaggcagt agcattcgac
    13801 gaagcgagtg acattggctt tgttcattgt catgaacact acccactctt gttgggttat
    13861 cacaattttg cgattttctt cccaggtgag ccacatcagc caactggtta tgcaggcatg
    13921 gaagaaaagg ttcggaaata tctctttaaa attttgattg attaaaaata ggatgaattg
    13981 tttttttgta aagctttgac aatactctac catgaaattg atctttgtga ggtagagaaa
    14041 tgagaataaa atatttaaaa attggtatct tctaagcatg ctgcaagagc tagtttctta
    14101 gatggacagg gaattacagt tgatgagatg tcctggataa ttaggggcat tgtgactgga
    14161 ttgattggcg gacacataaa attaggtgct tatgcagcta agtatggtat tagtatagca
    14221 cgatcgatct taagtagggc agctgcaact gcagcagcaa gagtaggatt actgaccaag
    14281 atttctggaa ggattttaca aatagctgtg aatgtagctg atgtatatgg taattttgcc
    14341 tacaatattg ctgcagcttg ggatgcacat gataaaatcc ctaacaatgg tcgtataaac
    14401 ttttaaaatg cgagaatgaa agcactttgt attttttatt gtatatgtta gcttggacag
    14461 tgcttgcaat gataatccgt ggaggaataa atggatttga tgaacacact tggcgtaata
    14521 ttttagctag tgcgttgtcc tcgctatata tacattatat atccatagat aaaaatagaa
    14581 aaagtccaaa agaaaaaaga aaaaatagat ttgttcatgg tagggactta tgaaagcttt
    14641 actgacaaaa aagaaaacag tttacaaaga aaaatgatgg aggagcaaac atggcacaaa
    14701 aaggagtaag ccttatcaag gcagcatttg atacagataa ctttctcatg cgttttagtg
    14761 agaaggtctt ggacatcgtg acagccaatc ttctttttgt cgtctcttgt ttacccatcg
    14821 tgacgattgg agtggctaaa atcagcctct acgagaccat gttcgaagtt aagaagagca
    14881 gacgggtgcc tgtttttaaa atctatctaa gatctttcaa gcaaaatctg aaactaggtc
    14941 ttcagctggg tttaatggag ttaggaattg tgtttcttac cctttcagat ctctatcttt
    15001 tctggggtca aacagctctg cccttccaat tgctgaaagc catttgttta ggtattctga
    15061 tttttcttac tatcgtgatg ctggctagtt accctatcgc ggcacgttat gacctatctt
    15121 ggaaagaaat tcttcaaaaa ggattgatgt tggctagttt taactttcct tggttcttcc
    15181 tcatgttagc cattcttgtc ctcattgtga tggttcttta tctgtccgcc ttcagtctac
    15241 tcttaggtgg ctcagtcttc ctactttttg ggtttggact attggtcttt atccagactg
    15301 gattgatgga gaaaattttc gcaaaatacc aataggagct ttatttctga aactactttc
    15361 aaaggctcca aacgctattc tataagcgag aaactaaaat ctaagtgtct ataagatatt
    15421 gaaagccttt tcggtaaagt gtatactaaa gaagtaaaga aaaatctgct ttagcagaaa
    15481 ataaaaataa taggagaaaa tctatgtcag atttgaaaaa atacgaaggt gtcattccag
    15541 ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg cgtgccttgg
    15601 ttcaatactt cattgataaa ggtgttcaag gtctttatgt caatggttct tctggtgaat
    15661 gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg gcggtagcca
    15721 aaggtaaatt gaccattatt gcccatgttg cttgcaataa tactaaagat agtatggaac
    15781 ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca ccaatttatt
    15841 tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct gcagctccaa
    15901 acacagacta cgtgatttac aacattcctc aattggcagg ggttgctttg actccaagcc
    15961 tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct tctatgccag
    16021 ttcaagatat ccaaaccttt gtcagccttg gtggagaaga ccatatcgtc tttaatggtc
    16081 ctgatgagca gttcctagga ggacgcctca tgggggctag ggctggtatc ggtggtactt
    16141 atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat aaggacctag
    16201 aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc acttctgctc
    16261 atggaaatat gtacggtgtc atcaaagaag tcttgaaaat caatgaaggc ttgaatattg
    16321 gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt gtagaagcgg
    16381 ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atctaaaagg aggtatttat
    16441 gacatattac gttgcaattg atatcggtgg aaccaacatc aagtatggtt tggttgatca
    16501 agaggggcaa cttcttgaat cgcatgaaat gccaactgag gcgcataagg gtggacctca
    16561 tatcttacaa aagaccaaag atatcgtagc tagttattta gaaaaaggcc cagtagcagg
    16621 tgttgccata tcttctgctg ggatggtgga tccggataag ggtgagattt tctatgctgg
    16681 gccgcaaatc cctaactacg caggcaccca gttcaaaaag gaaatcgaag aaagctttac
    16741 tattccttgt gagattgaaa atgatgtcaa ctgtgcaggt cttgctgagg cagtatctgg
    16801 ttcaggcaag ggagcaagta tgacactttg cttgaccatt ggaaccggta tcggtggttg
    16861 tttgattatg gataggaaag tcttccatgg ttttagtaat tcagcctgtg aagtcgggta
    16921 tatgcatatg caggatggag cttttcagga tctcgcttct acaacagctt tagtgaaata
    16981 tgtagctgaa gcccatggag aagatgttga tcagtggaat ggccgacgta tctttaagga
    17041 agctactgaa ggaaacaaaa tctgcatgga aggcattgac cgtatggttg actatctagg
    17101 aaaaggtctg gcaaatattt gctacgttgc caatccagaa gtggttattc ttggtggtgg
    17161 tatcatgggg caagaggcta tcctcaaacc taagatccgc acagccttga aagaggcttt
    17221 ggtaccaagt ttagcagaaa aaacacgatt agaatttgcc catcaccaaa atacagcagg
    17281 gatgttgggt gcatattatc attttaagac aaaacaatcc tagtttggct cagccaaact
    17341 aggattttct tacacgtttt tgtctacgat agccgttgag ttttttattt tcccagtagc
    17401 tattaaagat tttttccttg ctttcgcgat tgatttccaa aaagtaggca taaatcaaat
    17461 cgataaagaa gagcatagga agttgagcgg atattcgttg gatataggag ggttggctgt
    17521 gggtggctac aagaacagtc tctgtatagg tctggctatc tttattggga acacttgtaa
    17581 agagtacagt ctttgccccc atctccttgg catctaatag actatctaaa atagaaggag
    17641 ttgagcctga aagtgagaag cccagtacta gacaattttc atccatgatg ctggttgtcc
    17701 aggcaaagcc gtcttggtct gtcaaagctt cgcagaccac acctagtcgc ataaaacgta
    17761 atttcatttc acgggcgacg aggccagaac tccctgttcc aaagaagtag atacgctcag
    17821 catcttcgat tagctgggca attcgctcta gttggatttc gtcaatcaag tcttgtgttt
    17881 gttccctcat attgctataa cttctgagga ctcgtttggt cagtggactg tgcttggaga
    17941 cttggttggc ttgattttct gcctgatgtt ggtattggaa aataaattct cggtagccag
    18001 taaagccaca ctttttagca aagcgggtca aagcagcttg agaaatatgt aatttttggg
    18061 tgacttgttg agaagataaa tcatctgtaa tcgtttcagc ttgcaaaaaa tagcgagcga
    18121 tttcttgctc taggtctgtc atttcttcaa aatgtgaatc aatgatagtt gcgatatctg
    18181 gtttgtccat agggaaagct cctttacatg agtcatactg gaagactaga tcagggaata
    18241 gtcacacttc attataacac ataatataag gatagataaa taaaaacgca tctctgtttt
    18301 aaaaacgaaa aaatcgaaaa agcttctctc ttttccataa ttttctactc aaattgtggt
    18361 acaattaaga gtaagatttt aagttagaaa tgagactgat ttgtatgaga aaatttaaca
    18421 gccattcgat tccgattcgg cttaatttat tgttttcaat cgtcatttta ctctttatga
    18481 ccattattgg tcgtttgttg tatatgcagg ttttgaacaa ggatttttac gaaaaaaagc
    18541 tagcctcagc tagtcagacc aagattacaa gcagttcagc ccgtggggaa atttatgatg
    18601 ctagtggaaa acctttggta gaaaatacgt taaagcaggt tgtttccttt acgcgtagca
    18661 ataaaatgac ggctacagac ttaaaagaaa cagctaaaaa gttactgact tatgtgagca
    18721 tcagttctcc aaatttgaca gaacgccagc tggcggatta ctatttggct gatcctgaaa
    18781 tctataaaaa aatagtggaa gctctcccaa gtgagaaacg cttggattca gatggcaatc
    18841 gtctatccga atcagaactg tataacaatg cggtcgatag tgtacaaacg agtcaactaa
    18901 attatacaga ggatgaaaag aaagaaatct atctttttag tcagttaaat gctgttggaa
    18961 actttgcgac aggaaccatt gcgacagatc ctctaaatga ttctcaggtg gctgttattg
    19021 cctctatttc aaaggagatg cctggcatta gtatttctac ttcttgggat agaaaggttt
    19081 tggaaacttc cctttcttct atagttggga gtgtatccag tgaaaaagct ggtctcccag
    19141 cggaagaagc agaagcctat cttaaaaaag gctattctct aaatgatcgt gtaggaacct
    19201 cctatttgga aaagcaatat gaagagacct tacaaggaaa acgctcggta aaagaaatcc
    19261 atctggataa atatggaaat atggaaagcg tggatacaat tgaggaaggt agtaagggaa
    19321 acaatatcaa actgaccatt gatttggcct tccaagatag cgtggatgct ttactgaaaa
    19381 gttatttcaa ttccgagcta gaaaatggtg gagccaagta ttctgaaggt gtctatgcag
    19441 tcgcccttaa cccaaaaaca ggtgcggttt tgtctatgtc agggattaaa catgacttga
    19501 aaacgggaga gttgacgcct gattccttgg gaacggtaac caatgtcttt gttccaggtt
    19561 cggttgtcaa ggcggcgacc atcagctcag gttgggaaaa tggagtcttg tcaggaaacc
    19621 agaccttgac agaccagtcc attgtcttcc aaggttcagc tcccatcaat tcttggtata
    19681 ctcaggctta cggttcattc cctatcacag cggtccaagc tctggagtat tcatcaaata
    19741 cctatatggt ccaaacagcc ttaggtctta tggggcaaac ctatcaaccc aatatgtttg
    19801 tcggcaccag caatctagag tctgctatgg agaaactgcg ttcaaccttt ggcgaatatg
    19861 gcttgggtac tgcgacagga attgacctac cagatgaatc tactggattt gttcccaaag
    19921 agtatagctt tgctaattac attactaatg cctttgggca gtttgataac tatacgccga
    19981 tgcagttggc tcagtatgta gcaactattg caaataatgg tgttcgtgtg gctcctcgta
    20041 ttgttgaagg catttatggt aataatgata agggaggact gggtgacttg attcagcaac
    20101 tgcaaccgac agagatgaat aaggtcaata tatccgactc cgatatgagc atcttgcacc
    20161 aaggttttta tcaggttgcc catggtacta gtggattgac aactggacgt gccttttcaa
    20221 atggtgcctt ggtatccatt agcggaaaaa caggtacagc cgaaagctat gtggcagatg
    20281 gtcagcaagc aaccaatacc aatgcggtgg cctatgcccc atctgataat ccccaaatcg
    20341 ctgtcgcagt ggtctttcct cataatacca atctaacaaa tggtgtagga ccttccattg
    20401 cgcgtgacat tatcaatctg tatcaaaaat accatccaat gaactagaaa ggaaattatg
    20461 ctttatccaa cacctattgc caagttgatt gacagttatt ctaagttacc aggtatcggg
    20521 attaagacgg ctacgcgtct ggccttttat acgattggga tgtctgctga tgatgtcaat
    20581 gaatttgcaa aaaatctcct ttctgctaag agagaattga catattgttc tatttgtgga
    20641 cgtttgacag acgacgatcc ttgttctatc tgtactgatc cgactcgtga ccagacaaca
    20701 attttagttc ttgaggatag tagagatgtg gcagccatgg aaaatatcca agaataccat
    20761 ggactctatc atgtccttca tggcctcatt tctcctatga atggtatcag tccggacgat
    20821 atcaatctca agagccttat gactcgtctt atggatagtg aggtttcaga agtgattgtg
    20881 gcgactaatg ctacagcgga tggtgaagcg acttccatgt atctttcacg tttgctcaag
    20941 ccggctggta tcaaggttac gcgtctagca cgaggtctcg ctgtgggagc ggacattgag
    21001 tatgcggacg aagtgacact cttacgagcg attgaaaatc ggacagagtt gtaagtgtag
    21061 gcaaatttac gaactccctt catttataaa aaatcaaaga ggctgaaaat cgttcctatc
    21121 ggcctctttt cgtatagtgt gatgagtagg atcaggttca agttttaaaa aaccaagcaa
    21181 atatgatata ctaaagagcg agtattctag tagaattagg acaaataata tgaaacaaac
    21241 gattattctt ttatatggtg gacggagtgc ggaacgcgaa gtctctgtcc tttcagctga
    21301 gagtgtcatg cgtgcggtca attacgaccg tttcacagtc aagactttct ttatcagtca
    21361 gtcaggtgac tttatcaaaa cgcaggaatt tagtcatgct ccggggcaag aagaccgtct
    21421 catgaccaat gaaaccattg attgggataa gaaagttgca ccaagtgcta tctacgaaga
    21481 aggtgcagtg gtctttccag tccttcacgg gccaatggga gaagatggct ctgttcaagg
    21541 attcttggaa gttttgaaaa tgccttacgt tggttgcaac attttgtcat caagtcttgc
    21601 catggataaa atcacgacta agcgtgttct ggaatctgct ggtattgccc aagttcctta
    21661 tgtggctatc gttgaaggcg atgatgtgac tgctaaaatc gctgaagtgg aagaaaaatt
    21721 ggcttatcca gtcttcacta agccgtcaaa catggggtct agtgtcggta tttctaggtc
    21781 tgaaaaccaa gaagaactcc gtcaagcctt aaaacttgcc ttccgatatg acagccgtgt
    21841 cttggttgag caaggagtga atgcccgtga aattgaggtt ggcctcttgg gtaactacga
    21901 tgtcaagagc acgctacctg gagaagttgt caaggacgtt gccttttatg actacgatgc
    21961 caagtatatt gataacaagg ttactatgga tattcctgcc aaaatcagtg atgatgtggt
    22021 ggctgtcatg cgtcaaaatg cagaaacagc cttccgtgcc attggtggcc ttggtctatc
    22081 tcgttgcgat ttcttctata cagataaggg agagattttt ctcaacgagc tcaataccat
    22141 gccaggtttt acccagtggt ctatgtaccc actactttgg gacaatatgg ggatcagcta
    22201 cccagaacta atcgagcgtt tggttgacct tgccaaggaa agttttgaca agcgcgaagc
    22261 gcatttgata taaaatgaaa gagagggtag aagccagaac catcactgca cggtgactag
    22321 agttctcgga cttcagccct ttttaaagga gtagaaatga aattaacaat ccatgaaatt
    22381 gcccaagttg ttggagccaa aaatgatatc agtatctttg aggacaccca gttagaaaaa
    22441 gctgagtttg atagtcgttt gattggaact ggagatttat ttgtgccact taaaggtgcg
    22501 cgtgatggcc atgactttat tgaaacagcc tttgaaaatg gtgcagcagt aaccttgtct
    22561 gagaaagagg tctcaaatca tccttacatt ctagtagatg atgttttgac agcctttcaa
    22621 tccctagcat cctactatct tgaaaaaacg actgttgatg tctttgctgt tacaggttca
    22681 aatggcaaga caacgactaa ggatatgttg gcgcatttac tgtcaacgac ctacaagacc
    22741 tacaaaacac aaggcaacta caataacgag attggccttc cctacacagt tctacacatg
    22801 cctgaaggaa cagaaaagtt ggttttggag atggggcagg accacttggg cgatattcat
    22861 ctcttgtctg aattggctcg tccaaaaaca gccatcgtga ccttggttgg agaagcccat
    22921 ttggcctttt tcaaagaccg ttcagagatt gctaagggaa aaatgcaaat tgcagacgga
    22981 atggcttcag gttccttgct tttagtgccg gctgacccta tcgtagagga ctatttgcca
    23041 actgataaaa aggtggtccg ttttgggcaa ggggcagagt tggaaatcac agacttggtt
    23101 gagcgtaagg acagtctgac ctttaaggct aatttcttgg aacaagccct tgatttgcca
    23161 gtgactggta agtacaatgc taccaatgct atgattgcat cctatgttgc cctacaagaa
    23221 ggagtttcag aggagcaaat tcatcaggcc ttccaaggtc ttgaattgac gcgtaatcgt
    23281 actgagtgga agaaagcagc caatggagca gatatcctgt cagacgtata taatgccaat
    23341 ccaactgcta tgaagctgat tttagagact ttctctgcca ttccagccaa tgaaggtggc
    23401 aagaaaattg cagtgttggc ggatatgaag gagcttggtg accagtctat tcaactccat
    23461 aaccagatga ttttgagcct ttctccagat gtgcttgata ccgttatttt ctatggagaa
    23521 gacattgctg aattagccca attggccagt caaatgttcc caattggcca cgtttactac
    23581 ttcaagaaaa cagaagacca agaccaattt gaagacctag tcaagcaggt caaggaaagc
    23641 ctcagtgcca atgatcaaat cttgctcaag ggctctaact ctatgaacct agccatgttg
    23701 gtagaaagtt tagaaaatga aaccaagtga ttttgttaag tatctgcaaa gaatgattgc
    23761 ccttacagat actggcttaa cctttacaaa ggatcctttt gaccgtgagc gctacgagga
    23821 cttgcgaagt ctgttatctg aaatgttgaa tcagggatca gacctggatg cagaagaagt
    23881 agcagaagtc ttgaaaccaa cttcagctta tgcgactccc ttaatggacg tccgtgcttg
    23941 gattgttgag gatgagaaga tttgtctggt taggggacaa ggagaggata gttgggcttt
    24001 gccaggtggc tttggtgaag tcggctattc tccaactgaa aatattctca aggaaattga
    24061 agaagaaacc ggttttaaag ccaaagttga aagactgcta gctgtttttg ataccaatcg
    24121 tttccaacta cagagcaaac aatatgcaaa gtttgttttt gaatgtaagc ttctcgatgg
    24181 acaattccaa gaaaatcaag aaatcgctga ccttcaattt tttgcaattg accaactgcc
    24241 gaatttatct gaaaaacgca ttaccaagga gcaaatcgag attctttggc aggtttatca
    24301 aggtcagatg gagcaatatc ttgactaaga agatgattat cgtatttcta aattcatttt
    24361 tcttaagtag catggtataa taaaatgcag gaaaattttg aattatgagg aagactagat
    24421 gaatttatgg gatattttct ttacgactca ggcaaccgag ccgcccaaat ttgacctttt
    24481 ttggtatgtt agcctattta cgctcttagc cttaaccatt tatacagccc atcgctatcg
    24541 tgaaaagaag gtttaccaac gatttttcca aatcttgcag actgttcagt taatccttct
    24601 ttatggttgg tactgggtca atcatatgcc actgtcagaa agcctaccct tttaccattg
    24661 ccgtatggct atgtttgtgg tactcttgct tcctggtcag tccaaatata aacaatactt
    24721 tgcattattg ggaatatttg ggacattagc agcctttgtt tatccagtgc cagatgctta
    24781 cccttttcca catatcacca ttttatcctt tatctttggt catttagcac tcttggggaa
    24841 ctctctagtt tatctattga gacagtataa tgcgcgattg ctggatgtga agggaatttt
    24901 tctcatgacc tttgctctaa atgccttgat ttttgtggtc aatttggtga caggcggcga
    24961 ttacggattt ttgacaaaac cgccattggt tggggatcac ggtctagtag ctaattattt
    25021 acttgtttca attgtgctgg tagctactat cagtttgact aagaaaatct tagaattctt
    25081 tttagctcaa gaagcagaaa aaatgattgc aaaggaagct taacacagag ctttcttttt
    25141 tgctcttaga gagtttttac aagcagctta taaaataaga atttctgaat agacaaactc
    25201 aaaaaatggc tgggaaattt aggaaaaaaa caagcacgat taaatttttt gtgttataat
    25261 attttgtgaa tagctatgcc tatgtttagc tatggaataa tacgaagtgc gaaacttgga
    25321 agatagagag gaagcgatgt aatggctaga gaaggctttt ttacaggtct agatattgga
    25381 acaagctctg tcaaggtgct tgtggccgag cagagaactg gtgaattaaa tgtaattggc
    25441 gtgagtaatg ccaaaagtaa aggtgtaaag gatggaatta ttgttgatat tgatgcagca
    25501 gcaactgcta tcaagtcagc catttcccaa gcggaagaaa aggcaggcat ttcgattaaa
    25561 tcagtaaatg tcggcttgcc tggtaatctt ttgcaggtag aaccaactca ggggatgatt
    25621 ccagtaacat ctgatactaa ggaaattacg gatcaagatg ttgaaaatgt tgtcaaatca
    25681 gctttgacaa agagtatgac acctgaccgt gaagtcatta cctttattcc tgaagaattt
    25741 attgtggatg gtttccaagg gattcgtgac ccacgtggca tgatgggggt tcgccttgaa
    25801 atgcgtggtt tgctttatac aggacctcgt actatcttgc acaatttgcg taagacggtt
    25861 gagcgtgcag gtgttcaggt tgaaaatgtt atcatttcac cactagcaat ggttcagtct
    25921 gttttgaacg aaggggaacg tgaatttggt gctacagtga ttgatatggg ggcaggtcaa
    25981 acgactgtcg ctacaatccg taatcaagaa ctccagttca cacatattct ccaagaaggt
    26041 ggagattatg taactaaaga tatctccaag gttttgaaaa cctctcgcaa attagcggaa
    26101 ggcttgaaac tgaattacgg ggaagcctat ccgcctcttg caagcaaaga aaccttccaa
    26161 gtagaggtta ttggagaagt agaagcagtc gaagtgacgg aagcctactt gtcagaaatt
    26221 atttctgcac gaatcaagca catccttgaa caaatcaagc aagaattaga tagaaggcgt
    26281 ctattggacc tccctggtgg tattgtctta atcggtggga atgccatttt accaggtatg
    26341 gttgagcttg ctcaggaagt ctttggcgtc cgtgtcaagc tttatgttcc aaatcaagtt
    26401 ggtatccgta atccagcctt tgcgcatgtg attagtttat cagaatttgc gggtcaatta
    26461 acagaagtta atcttttggc tcagggagcg ataaaaggtg agaatgactt aagtcatcag
    26521 ccaattagtt ttggtgggat gctgcaaaaa acagctcagt ttgtacaatc aacgcctgtt
    26581 caaccagctc ctgctccaga agtagagccg gtggcgccta cagaaccaat ggcggatttc
    26641 caacaagctt cacaaaataa accgaaatta gcagatcgtt tccgtggctt gatcggaagc
    26701 atgtttgacg aataaagagg aaaaataaat tatgacattt tcatttgata cagctgctgc
    26761 tcaaggggca gtgattaaag taattggtgt cggtggaggt ggtggcaatg ccatcaaccg
    26821 tatggtcgac gaaggtgtta caggcgtaga atttatcgca gcaaacacag atgtacaagc
    26881 attgagtagt acaaaagctg agactgttat tcagttggga cctaaattga ctcgtggttt
    26941 gggtgcagga ggtcaacctg aggttggtcg taaagccgct gaagaaagcg aagaaacact
    27001 gacggaagct attagtggtg ccgatatggt cttcatcact gctggtatgg gaggaggctc
    27061 tggaactgga gctgctcctg ttattgctcg tatcgccaaa gatttaggtg cgcttacagt
    27121 tggtgttgta acacgtccct ttggttttga aggaagtaag cgtggacaat ttgctgtaga
    27181 aggaatcaat caacttcgtg agcatgtaga cactctattg attatctcaa acaacaattt
    27241 gcttgaaatt gttgataaga aaacaccgct tttggaggct cttagcgaag cggataacgt
    27301 tcttcgtcaa ggtgttcaag ggattaccga tttgattacc aatccaggat tgattaacct
    27361 tgactttgcc gatgtgaaaa cggtaatggc aaacaaaggg aatgctctta tgggtattgg
    27421 tatcggtagt ggagaagaac gtgtggtaga agcggcacgt aaggcaatct attcaccact
    27481 tcttgaaaca actattgacg gtgctgagga tgttatcgtc aacgttactg gtggtcttga
    27541 cttaaccttg attgaggcag aagaggcttc acaaattgtg aaccaggcag caggtcaagg
    27601 agtgaacatc tggctcggta cttcaattga tgaaagtatg cgtgatgaaa ttcgtgtaac
    27661 agttgtcgca acgggtgttc gtcaagaccg cgtagaaaag gttgtggctc cacaagctag
    27721 atctgctact aactaccgtg agacagtgaa accagctcat tcacatggct ttgatcgtca
    27781 ttttgatatg gcagaaacag ctgaattgcc aaaacaaaat ccacgtcgtt tggaaccaac
    27841 tcaggcatct gcttttggtg attgggatct tcgccgtgaa tcgattgttc gtacaacaga
    27901 ttcagtcgtt tctccagtcg agcgctttga agccccaatt tcacaagatg aagatgaatt
    27961 ggatacacct ccatttttca aaaatcgtta agtaaatgaa tgtaaaagaa aatacagaac
    28021 ttgtttttcg agaagttgca gaggctagtc tgagtgctaa tcgagagagt ggttcggtct
    28081 ctgtcattgc agttaccaag tatgtagatg taccgacagc ggaagccttg cttccgctag
    28141 gtgttcatca tatcggtgaa aatcgtgtag ataagtttct ggaaaaatat gaagctttaa
    28201 aagatcgaga tgtgacttgg catttgattg gtaccttgca aagacgtaag gtgaaagatg
    28261 tcattcaata cgttgattat ttccatgcat tggactcagt aaagctagca ggggaaattc
    28321 aaaaaagaag tgaccgagtc atcaagtgtt tccttcaagt aaatatttct aaagaagaaa
    28381 gcaaacacgg tttttcgaga gaggaactga tggaaatctt gccagagtta gccagactag
    28441 ataagattga atatgttggt ttaatgacga tggcaccttt tgaggctagc agtgagcagt
    28501 tgaaagagat tttcaaggcg acccaagatt tacaaagaga aattcaagag aaacaaattc
    28561 caaatatgcc tatgaccgag ttaagtatgg gaatgagtcg tgattataaa gaagcgattc
    28621 aattcggttc cacttttgtt cgtataggta catcattttt taagtaggag agaaccatgt
    28681 ctttaaaaga tagattcgat agatttatag attattttac ggagaatgag gattcaagtc
    28741 tcccttatga aaaaagagat gagcctgtgt ttactccagt aaattcttca caggaaccgg
    28801 ctctcccaat gaatcaacct tcacagtcgg ctggtacaaa agagaacaat atcaccagac
    28861 ttcatgcaag acaacaggaa ttggcaaatc agagtcagcg tgcaacggat aaggtcatta
    28921 tagatgttcg ttatcctaga aaatatgagg atgcaacaga aattgttgat ttattggcag
    28981 gaaacgaaag tatcttgatt gattttcagt atatgacaga ggtgcaggct cgtcgttgtt
    29041 tggactattt ggatggagct tgtcatgttt tagctggaaa tttgaaaaag gtagcttcta
    29101 ccatgtattt gttgacacca gtgaatgtta ttgtaaatgt tgaagatatc cgtttaccag
    29161 atgaagatca acagggtgag ttcggttttg atatgaagcg aaatagagta cgataatgat
    29221 ttttttaatt cgtatgattt ataatgcagt ggatatttac tccctgattt tggtagcctt
    29281 cgctgtcatg tcttggtttc caggtgccta cgaatccagt ttaggtcgtt ggattgtagc
    29341 gttggtgaaa ccagtgcttg ctcccttgca acgcctgcct ttacagatag cgggtcttga
    29401 tttatctatt tgggtcgcga ttgttttggt tcgattttta ggagaaaacc tagtgcgttt
    29461 tctggcgatg ataggatgaa taaagggatt tatcagcatt tctccataga agatcgtcca
    29521 tttcttgaca agggaatgga atggataaag aaggtagaag atagctatgc tcctttttta
    29581 actcctttta tcaatcctca tcaggagaag ctattaaaga ttttggccaa aacctatggt
    29641 cttgcttgta gcagtagtgg ggaattcgtc tcgagtgagt atgttcgagt tttattatac
    29701 ccagattatt tccaaccaga gttttcagat tttgaaatat ctctccagga aattgtgtat
    29761 tccaataaat ttgaacattt aacgcatgct aagattttag ggacagtcat caatcaatta
    29821 gggattgaac ggaaactttt tggagatatc ctagtagatg aagaacgggc gcagattatg
    29881 attaatcagc agtttcttct tctctttcaa gatggactaa agaaaattgg tcgtatacct
    29941 gtttcgctgg aggaacgtcc tttcaccgag aaaatagata agctagaaca gtatcgagaa
    30001 ctggatttat ctgtgtctag ttttcgatta gatgttcttt tatcaaatgt tttgaaacta
    30061 tctaggaatc aagcaaacca gttgattgaa aagaaacttg tccaagtaaa ttatcatgtg
    30121 gtagacaaat cagattacac tgttcaagtt ggagacttga ttagtgtgag aaaatttggt
    30181 cgcttgagat tacttcaaga taagggacaa acgaaaaaag agaagaaaaa aataaccgtc
    30241 cagttattat taagtaagtg aggaatagaa tgccaattac atcattagaa ataaaggaca
    30301 agacttttgg aactcgattc agaggttttg atccagaaga agtcgatgaa tttttagata
    30361 ttgtggttca tgattacgaa gatcttgtgc gtgcgaatca tgataaaaat ttgcgtatta
    30421 agagtttaga agagcgtttg tcttactttg atgaaataaa agattcattg agccagtctg
    30481 tattgattgc tcaggataca gctgagagag tgaaacaggc ggcgcatgaa cgttcaaaca
    30541 atatcattca tcaagcagag caagatgcgc aacgcttgtt ggaagaagct aaatataagg
    30601 caaacgagat tcttcgtcaa gcaactgata atgctaagaa agtcgctgtt gaaacagaag
    30661 aattgaagaa caagagccgt gtcttccacc aacgtctcaa atctacaatt gagagtcagt
    30721 tggctattgt tgaatcttca gattgggaag atcttctccg tccaacagct acttatcttc
    30781 aaaccagtga tgaagccttt aaagaagtgg ttagcaaagt acttggagaa ccgattccag
    30841 ctccaattga agaagaacca attgatatga cacgtcagtt ctctcaagca gaaatggcag
    30901 agttacaagc tcgtattgag gtagccgata aagaattggc tgaatttgaa gctcagatta
    30961 aacaggaagt ggaagctcca acttgtagtg agtcctcagg ttgaagaaga gcctctgctc
    31021 atccagttgg cccaatgtat gaagaaccag aagtagctcc agtgcatccg acaggtccaa
    31081 caccagctac agaaactgtt gattcaatac cgggatttga agcaccgcaa gaatctgtta
    31141 caattttata agaaatattc tgagaacaat atcttatcct tatatttcca gcgagcagga
    31201 aatggtgtga gtcctgcatt ccctatcgat aagattatcc tctcaaacta tcaagtctga
    31261 atctagtaag atttgacgtt ccccacgtta cgggataaga gagagaaaga ctaaatcttt
    31321 ttccgaataa aggtggtacc acgattttcg tcctttttgg aagtcgtggt ttttaatttg
    31381 ttattattta taaaggagat accatgaaac tcaaagacac ccttaatctt gggaaaactg
    31441 aattcccaat gcgtgcaggc cttcctacca aagagccagt ttggcaaaag gaatgggaag
    31501 atgcaaaact ttatcaacgt cgtcaagaat tgaaccaagg aaaacctcat ttcaccttgc
    31561 atgatggccc tccatacgct aacggaaata tccacgttgg acatgctatg aacaagattt
    31621 caaaagatat cattgttcgt tctaagtcta tgtcaggatt ttacgcgcca tttattcctg
    31681 gttgggatac tcatggtctg ccaatcgagc aagtcttgtc aaaacaaggt gtcaaacgta
    31741 aagaaatgga cttggttgag tacttgaaac tttgccgtga gtacgctctt tctcaagtag
    31801 ataaacaacg tgaagatttt aaacgtttgg gtgtttctgg tgactgggaa aatccatatg
    31861 tgaccttgac tcctgactat gaagcagctc aaattcgtgt atttggtgag atggctaata
    31921 agggttatat ctaccgtggt gccaagccag tttactggtc atggtcatct gagtcagccc
    31981 ttgctgaagc agagattgaa taccatgact tggtttcaac ttccctttac tatgccaaca
    32041 aggtaaaaga tggcaaagga gttctagata cagatactta tatcgttgtc tggacaacga
    32101 ctccatttac catcacagct tctcgtggtt tgacggttgg tgcagatatt gattacgttt
    32161 tggttcaacc tgctggtgaa gctcgtaagt ttgtcgttgc tgctgaatta ttgactagct
    32221 tgtctgagaa atttggctgg gctgatgttc aagttttgga aacttaccgt ggccaagaac
    32281 ttaaccacat cgtaacagaa cacccatggg atacagctgt agaagagttg gtaattcttg
    32341 gtgaccacgt tacgactgac tctggtacag gtattgtcca tacagcccct ggttttggtg
    32401 aggacgacta caatgttggt attgctaata atcttgaagt cgcagtgact gttgatgaac
    32461 gtggtatcat gatgaagaat gctggtcctg agtttgaagg tcaattctat gaaaaggtag
    32521 ttccaactgt tattgaaaaa cttggtaacc tccttcttgc ccaagaagaa atctctcact
    32581 catatccatt tgactggcgt actaagaaac caatcatctg gcgtgcagtt ccacaatggt
    32641 ttgcctcagt ttctaaattc cgtcaagaaa tcttggacga aattgaaaaa gtgaaattcc
    32701 actcagaatg gggtaaagtc cgtctttaca atatgatccg tgaccgtggt gactgggtta
    32761 tctctcgtca acgtgcttgg ggtgttccac ttccaatctt ctatgcagaa gacggtacag
    32821 ctatcatggt agctgaaacg attgaacacg tagctcaact ttttgaagaa catggttcaa
    32881 gcatttggtg ggaacgtgat gccaaagatc tcttgccaga aggatttact catccaggtt
    32941 caccaaacgg cgagttcaaa aaagaaactg atatcatgga cgtttggttt gactcaggtt
    33001 catcatggaa tggagtggtg gtaaaccgtc ctgaattgac ttacccagcc gacctttacc
    33061 tagaaggttc tgaccaatac cgtggttggt ttaactcatc acttatcaca tctgttgcca
    33121 accatggcgt agcaccttac aaacaaatct tgtcacaagg ttttgccctt gatggtaaag
    33181 gtgagaagat gtctaaatct cttggaaata ccattgctcc aagcgatgtt gaaaaacaat
    33241 tcggtgctga aatcttgcgt ctctgggtaa caagtgttga ctcaagcaat gacgtgcgta
    33301 tctctatgga tattttgagc caagtttctg aaacttaccg taagattcgt aacactcttc
    33361 gtttcttgat tgccaataca tctgacttta acccagctca agatacagtc gcttacgatg
    33421 agcttcgttc agttgataag tacatgacga ttcgctttaa ccagcttgtc aagaccattc
    33481 gtgatgccta tgcagacttt gaattcttga cgatctacaa ggccttggtg aactttatca
    33541 acgttgactt gtcagccttc taccttgatt ttgccaaaga tgttgtttac attgaaggtg
    33601 ccaaatcact ggaacgccgt caaatgcaga ctgtcttcta tgacattctt gtcaaaatca
    33661 ccaaactctt gacaccaatc cttcctcaca ctgcggaaga aatttggtca tatcttgagt
    33721 ttgaaacaga agacttcgtc caattgtcag aattaccaga ggctcaaact tttgctaatc
    33781 aagaagaaat cttggataca tgggcagcct tcatggactt ccgtggacaa gctcaaaaag
    33841 ccttggaaga agctcgtaat gcaaaagtaa tcggtaaatc acttgaagca cacttgacag
    33901 tttatccaaa cgaagttgtg aaaactctac tcgaagcagt aaacagcaat gtggctcaac
    33961 ttttgatcgt gtcagacttg accatcgcag aaggaccagc tccagaagct gcccttagct
    34021 tcgaagatgt agccttcaca gttgaacgcg ctgcaggtga agtatgtgac cgttgccgtc
    34081 gtattgaccc aacaacagca gaacgtagct accaggcagt tatctgtgac cactgtgcaa
    34141 gcatcgtaga agaaaacttt gcggaagcag tcgcagaagg atttgaagag aaataagatt
    34201 gaaaagtcta ggcaaaattc aatttgagaa gaaaagacaa ctaattttat agtctattaa
    34261 acgcattgta tcacgttttt gaacacctga tatgatgcgt tttttattta ttttaaaaat
    34321 ttgcgaggta tgacttttta tactcaacaa gaatcaaaga gaaacttagc aagctaacag
    34381 t
//
LOCUS       DAVKBC010000019        33933 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVKBC010000019 DAVKBC010000000
VERSION     DAVKBC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33933
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.019"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            109..705
                     /locus_tag="VWX64_001056"
                     /pseudo
     CDS             109..705
                     /locus_tag="VWX64_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            781..1230
                     /locus_tag="VWX64_001057"
     CDS             781..1230
                     /locus_tag="VWX64_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9190537.1"
                     /translation="MCTILVSIYYKIGLSSSGVYKAVADGEMTVGLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVL
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            1243..2334
                     /locus_tag="VWX64_001058"
     CDS             1243..2334
                     /locus_tag="VWX64_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190538.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLGLMQIAQYADRKPDKLSGGQQQRVTLACVLAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEELQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            2324..3969
                     /locus_tag="VWX64_001059"
                     /pseudo
     CDS             2324..3969
                     /locus_tag="VWX64_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(4072..4764)
                     /locus_tag="VWX64_001060"
     CDS             complement(4072..4764)
                     /locus_tag="VWX64_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9190539.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLISGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(5008..6345)
                     /locus_tag="VWX64_001061"
     CDS             complement(5008..6345)
                     /locus_tag="VWX64_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU9190540.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(6355..6621)
                     /locus_tag="VWX64_001062"
     CDS             complement(6355..6621)
                     /locus_tag="VWX64_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU9190541.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(6886..7272)
                     /gene="rplQ"
                     /locus_tag="VWX64_001063"
     CDS             complement(6886..7272)
                     /gene="rplQ"
                     /locus_tag="VWX64_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU9190542.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(7284..8219)
                     /locus_tag="VWX64_001064"
     CDS             complement(7284..8219)
                     /locus_tag="VWX64_001064"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU9190543.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNLDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(8262..8645)
                     /gene="rpsK"
                     /locus_tag="VWX64_001065"
     CDS             complement(8262..8645)
                     /gene="rpsK"
                     /locus_tag="VWX64_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU9190544.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(8663..9028)
                     /gene="rpsM"
                     /locus_tag="VWX64_001066"
     CDS             complement(8663..9028)
                     /gene="rpsM"
                     /locus_tag="VWX64_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU9190545.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(9046..9162)
                     /gene="rpmJ"
                     /locus_tag="VWX64_001067"
     CDS             complement(9046..9162)
                     /gene="rpmJ"
                     /locus_tag="VWX64_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU9190546.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(9187..9405)
                     /gene="infA"
                     /locus_tag="VWX64_001068"
     CDS             complement(9187..9405)
                     /gene="infA"
                     /locus_tag="VWX64_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU9190547.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(9522..10160)
                     /locus_tag="VWX64_001069"
     CDS             complement(9522..10160)
                     /locus_tag="VWX64_001069"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU9190548.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(10311..11621)
                     /gene="secY"
                     /locus_tag="VWX64_001070"
     CDS             complement(10311..11621)
                     /gene="secY"
                     /locus_tag="VWX64_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU9190549.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(11634..12074)
                     /gene="rplO"
                     /locus_tag="VWX64_001071"
     CDS             complement(11634..12074)
                     /gene="rplO"
                     /locus_tag="VWX64_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU9190550.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(12219..12443)
                     /gene="rpmD"
                     /locus_tag="VWX64_001072"
     CDS             complement(12219..12443)
                     /gene="rpmD"
                     /locus_tag="VWX64_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU9190551.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(12415..12909)
                     /gene="rpsE"
                     /locus_tag="VWX64_001073"
     CDS             complement(12415..12909)
                     /gene="rpsE"
                     /locus_tag="VWX64_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU9190552.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(12927..13283)
                     /gene="rplR"
                     /locus_tag="VWX64_001074"
     CDS             complement(12927..13283)
                     /gene="rplR"
                     /locus_tag="VWX64_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU9190553.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(13367..13903)
                     /gene="rplF"
                     /locus_tag="VWX64_001075"
     CDS             complement(13367..13903)
                     /gene="rplF"
                     /locus_tag="VWX64_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU9190554.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(14095..14493)
                     /gene="rpsH"
                     /locus_tag="VWX64_001076"
     CDS             complement(14095..14493)
                     /gene="rpsH"
                     /locus_tag="VWX64_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU9190555.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(14778..15047)
                     /gene="rpsN"
                     /locus_tag="VWX64_001077"
     CDS             complement(14778..15047)
                     /gene="rpsN"
                     /locus_tag="VWX64_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU9190556.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(15065..15607)
                     /gene="rplE"
                     /locus_tag="VWX64_001078"
     CDS             complement(15065..15607)
                     /gene="rplE"
                     /locus_tag="VWX64_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU9190557.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(15631..15936)
                     /gene="rplX"
                     /locus_tag="VWX64_001079"
     CDS             complement(15631..15936)
                     /gene="rplX"
                     /locus_tag="VWX64_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU9190558.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(16014..16382)
                     /gene="rplN"
                     /locus_tag="VWX64_001080"
     CDS             complement(16014..16382)
                     /gene="rplN"
                     /locus_tag="VWX64_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU9190559.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(16408..16668)
                     /gene="rpsQ"
                     /locus_tag="VWX64_001081"
     CDS             complement(16408..16668)
                     /gene="rpsQ"
                     /locus_tag="VWX64_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU9190560.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(16693..16899)
                     /locus_tag="VWX64_001082"
     CDS             complement(16693..16899)
                     /locus_tag="VWX64_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU9190561.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(16909..17322)
                     /gene="rplP"
                     /locus_tag="VWX64_001083"
     CDS             complement(16909..17322)
                     /gene="rplP"
                     /locus_tag="VWX64_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU9190562.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(17326..17979)
                     /gene="rpsC"
                     /locus_tag="VWX64_001084"
     CDS             complement(17326..17979)
                     /gene="rpsC"
                     /locus_tag="VWX64_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU9190563.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(17992..18336)
                     /gene="rplV"
                     /locus_tag="VWX64_001085"
     CDS             complement(17992..18336)
                     /gene="rplV"
                     /locus_tag="VWX64_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU9190564.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(18348..18629)
                     /gene="rpsS"
                     /locus_tag="VWX64_001086"
     CDS             complement(18348..18629)
                     /gene="rpsS"
                     /locus_tag="VWX64_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU9190565.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(18733..19566)
                     /gene="rplB"
                     /locus_tag="VWX64_001087"
     CDS             complement(18733..19566)
                     /gene="rplB"
                     /locus_tag="VWX64_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU9190566.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(19584..19880)
                     /locus_tag="VWX64_001088"
     CDS             complement(19584..19880)
                     /locus_tag="VWX64_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU9190567.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(19880..20503)
                     /gene="rplD"
                     /locus_tag="VWX64_001089"
     CDS             complement(19880..20503)
                     /gene="rplD"
                     /locus_tag="VWX64_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU9190568.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(20528..21154)
                     /gene="rplC"
                     /locus_tag="VWX64_001090"
     CDS             complement(20528..21154)
                     /gene="rplC"
                     /locus_tag="VWX64_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU9190569.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(21371..21679)
                     /gene="rpsJ"
                     /locus_tag="VWX64_001091"
     CDS             complement(21371..21679)
                     /gene="rpsJ"
                     /locus_tag="VWX64_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU9190570.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(21945..22562)
                     /locus_tag="VWX64_001092"
     CDS             complement(21945..22562)
                     /locus_tag="VWX64_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU9190571.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(22559..23149)
                     /gene="nrdG"
                     /locus_tag="VWX64_001093"
     CDS             complement(22559..23149)
                     /gene="nrdG"
                     /locus_tag="VWX64_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU9190572.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGILYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            complement(23142..23648)
                     /locus_tag="VWX64_001094"
     CDS             complement(23142..23648)
                     /locus_tag="VWX64_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190573.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            complement(23692..23832)
                     /locus_tag="VWX64_001095"
     CDS             complement(23692..23832)
                     /locus_tag="VWX64_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190574.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(23844..26051)
                     /gene="nrdD"
                     /locus_tag="VWX64_001096"
     CDS             complement(23844..26051)
                     /gene="nrdD"
                     /locus_tag="VWX64_001096"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU9190575.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(26171..27709)
                     /locus_tag="VWX64_001097"
     CDS             complement(26171..27709)
                     /locus_tag="VWX64_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU9190576.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLQVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVEVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(27967..29499)
                     /gene="cls"
                     /locus_tag="VWX64_001098"
     CDS             complement(27967..29499)
                     /gene="cls"
                     /locus_tag="VWX64_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU9190577.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGINLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(29645..30163)
                     /locus_tag="VWX64_001099"
     CDS             complement(29645..30163)
                     /locus_tag="VWX64_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU9190578.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDG
                     DRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDM
                     DRDPSDQIVLTK"
     gene            complement(30160..31410)
                     /locus_tag="VWX64_001100"
     CDS             complement(30160..31410)
                     /locus_tag="VWX64_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9190579.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(31717..32022)
                     /locus_tag="VWX64_001101"
     CDS             complement(31717..32022)
                     /locus_tag="VWX64_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU9190580.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(32038..32457)
                     /gene="ruvX"
                     /locus_tag="VWX64_001102"
     CDS             complement(32038..32457)
                     /gene="ruvX"
                     /locus_tag="VWX64_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU9190581.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(32461..32727)
                     /locus_tag="VWX64_001103"
     CDS             complement(32461..32727)
                     /locus_tag="VWX64_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU9190582.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(32814..33383)
                     /locus_tag="VWX64_001104"
     CDS             complement(32814..33383)
                     /locus_tag="VWX64_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU9190583.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSNYISDRLANGATEQ"
     gene            complement(33449..33847)
                     /gene="spx"
                     /locus_tag="VWX64_001105"
     CDS             complement(33449..33847)
                     /gene="spx"
                     /locus_tag="VWX64_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU9190584.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT         9673 a         7512 c         6201 g        10547 t
ORIGIN      
        1 caaagtgtac tgttatagat tcaatacact atagaataga attgtaggtt ttaaaaacgc
       61 ttacattgtt ttaaaataaa cttaaataac acaacggagg tatccatcat gaaaaagaaa
      121 tggatgtatt atgctgcttg ttcttctaat gaatctgccg atgacagttc atctgataaa
      181 ggagacggtg gttcgctagt cgtttattga ccaaactcag aaggcttaat tggagcaact
      241 attcctgcct ttgaagaaaa atatggtatc aaaatagaac tgattcaagc tggtactgga
      301 gaacttttca aaaaactaga gtcagaaaaa gaagttcctg tagctgatgt tatctttggt
      361 ggttcttata cacaatatgc tacccacgga gaactctttg aaaactatat ttcaaaagaa
      421 aatgataatg ttatcaaaga atatcaaaac acaactggct tctctactcc ttatacacta
      481 gatggtagtg ttttaatcgt ccaccctgat ttaactaaag gcatgaacat cgaaggatat
      541 agcgaccttc tcaaacctga actaaaagga aaaatcgcaa ctgctgaccc agcaaactct
      601 tctagcgcct ttgctcaatt aacaaatatg ctacaagctc aaggtggtta caaagatgat
      661 aaggcttggt cttatgtaaa agatcttttc acacttattg atggtatagt aaaatgaaat
      721 aagaacaaga caaattaatc aggacagtca aatcgatttc taacaatgtt ttagaagtag
      781 atgtgtacta ttctagtttc aatatactat aaaatcggtt taagttcatc tggtgtctat
      841 aaagcagtcg ctgatggaga aatgactgtt ggtctctctt atgaagatcc agcagttaaa
      901 ctcttaaatg acggagctaa cattaaggta gtctatccaa aagaaggaac cgtcttccta
      961 cctgctagtg ctgctatcgt taaaaaatct aaaaatatgg aaaatgccaa gaaatttatc
     1021 gattttatta tctctcaaga agtacaagat acacttggta caaccactac taaccgtcct
     1081 gttcttaaaa atgctaaaac aagcgaaaac atgaaaccaa ttgacaaaat caaaacactc
     1141 actgaagatt atgattatgt catcaagaat aaatcagata tcgttaagaa atacaacgaa
     1201 gtctttacag atatccaatc taaacagtaa aagaggttca ctatgagtga gatcgaaatt
     1261 attaacgcca aaaaaatcta ccacgatgtc cctgttattg agaatttgaa cattacaatt
     1321 ccaaaaggaa gtctctttac ccttcttgga gcttcaggat gtgggaaaac gacccttctt
     1381 cgtatgattg caggtttcaa cagtatcaaa gatggagaat tttacttcga tgatacaaaa
     1441 atcaataata tggaacccag caaacgcaat atcgggctgg ttttccaaaa ctacgctatt
     1501 ttcccacatt tgactgtccg agacaacgtt gcttttggtc ttatgcaaaa gaaggttcca
     1561 aaagaagaat tgattcaaca gaccaacaag tatcttggac tcatgcaaat tgctcaatat
     1621 gcggatcgaa agcccgataa actcagtggt ggacaacaac aacgtgtcac cttggcatgc
     1681 gtcttagcgg ttaatccaag tgttctcctc atggacgagc cacttagtaa tctggaggcc
     1741 aaacttcgct tggatatgcg tcaagccatc cgagaaatcc aacacgaagt gggaattaca
     1801 actgtttatg taacccacga ccaagaagaa gccatggcta tttcagacca aattgctgtt
     1861 atgaaagatg gggtgatcca acaaatcggc cgaccaaaag aactctatca taaaccagct
     1921 aatgagtttg tggcaacctt tatcggacgc acaaatatta tccctgccaa tcttgaaaaa
     1981 cggagcgacg gcgcttatat cgtcttttca gatggctatg cccttcgaat gctagctctt
     2041 gatcaggttg aggagcaagc tattcatgta agcattcgtc ccgaagagtt tatcaaagat
     2101 gaatctggag atattgaagg aactattagc gatagcgtct atcttggact aaatacggag
     2161 tatttcattg agacaggttt tgcctcaaaa attcaagtta gtgaagaatc aacttttgaa
     2221 gaagaactac aaaaaggcaa tcgtattcgt ctacgaatca atacgcaaaa attaaacatc
     2281 ttttctgcag atggttccca aaacctgata aaaggagtca accatggaac gtaaaaaact
     2341 aaatatttgg acagcctcct ctttcttcat ctttcttacc tatcttgtct ttctcgttta
     2401 tcctatcgtt accgtgctca agtaagcact tatacatgaa ggataattct cactagctaa
     2461 ttttgtcact ttctttagta aagcctacta ctctgagaca ctagtcaaca gtttcagggt
     2521 ttccattacc gctactgtca cttccttagt tgtaggaacc ctattagctt atctcttctc
     2581 tatgtatgac ttcaagggga agaaatttct acaaatattg attatcattg cttccatgtc
     2641 aactcctttc gtaggagcct actcctggat tctcttgctg ggacgaaatg aggtcatcac
     2701 taaatttttg acaaatgccc tttatcttcc agctatcgat atttatggat tcaaaggaat
     2761 tatacttgtc tttacactgc aactattccc actggtattt ctatatgttg ctggaacaat
     2821 gaacagtatt gacaattctc tacttgaagc agctgaaagc atggggtcct tcggatttaa
     2881 acctatcgta acggttgttt tacctctcct agttccaacc ttactagcag ctccttgctt
     2941 gtatttatga gagcattctc agactttgga acgcctatgt tgattggcga aggatatcgg
     3001 actttccctg tcctgattta tacccaattt attagcgagg ttggaggaaa ttctgctttt
     3061 gcaattatgg cgattatcat tgccttggca attttcctta tccaaaaaca cattgcaaac
     3121 cgctacagtt tcagcatgaa tctgctccat ccaattgagc ctaaaaaaac tacaaaagga
     3181 aaaatggctg ccatttatgc aacagtctac ggaattatct ttatctctgt tttacctcaa
     3241 atctacttaa tttatacctc tttcctaaaa acatcaggta tggtatttgt taaaggttat
     3301 tctccaaaca gttacaaggt agctttcaat cgtatgggat ctgctatttt caataccatt
     3361 cgtatccctt tgattgcctt agttctagtt gttctattta cgacatttat ctcctaccta
     3421 gccgttagaa aacggaattt gtttacaaac ttaattgaca gcctcagtat ggtaccttat
     3481 attgtaccag gaaccgttct agggattgcc ttcatttctt ccttcaatac tggtctattt
     3541 ggaagtggat ttcttatgat tacagggact gctttcatct tgattatgtc tctatctgtc
     3601 agaagattac cgtatactat tcgctcatct gttgctagct tacaacaaat agcaccaagt
     3661 attgaagaag ctgctgaaag cttaggaagt agtcgtctca atacctttgc taagattaca
     3721 actccaatga tgctatctgg tatcatttct ggagccatct tatcttgggt cacaatgatt
     3781 tcaaaactct ctacttctat cctcctctac aatgtcaaaa caagaacaat gactgtagct
     3841 atttatacag aggttctcag aggaaattac ggtgtagccg cagccttgtc aactatcctg
     3901 actgttctaa cagtaggttc cttgctcttg tttatgaaaa tctctaaaag caatagcatt
     3961 acactttagt tttccacatc aaaaacagcc gaaaggagta ccctcggctg ttttttctta
     4021 tcttgatatt cttatcaaat ccctagctca tggcaagcaa gtctagactg attaaataga
     4081 gccttcttcc atcttctcac gtcctagctc tcggtaacta cggtcaccga caacttcaac
     4141 cctaaactga ccgtcctcat attcaagaat cgtcacgcta ccattatcta gaccatgcgg
     4201 atgcatgcca ctaatcagat aaacaatggt tccaatagtc attccatggc tgacaacaag
     4261 ggcgttacct ccaccttgat cttccatttc ttttgcaatc atttcaaagc cttccttgat
     4321 tcggccactg agtttttccc agccttcagc ccaaccagct gtatcgacct ctaccaagcc
     4381 ctcagccagt tcagcataag acaattggtg aacgtggtcc acattaaaga tacgaggaat
     4441 aatgcccatg aaaagatcgc catcataggc tccatcaaaa ctaccgaaac accattctct
     4501 gatacgcttg tccatgcgat aagggatttt cccctgcaag ccaagttctt caaggataat
     4561 tcccatggtc tgaatggtac gaccagaatc actcgaataa gcgcgctcaa actgtagatc
     4621 agattctcgc aaaccgattc ctaactcttg aatccctcgt tcaccttcag cagttaaggg
     4681 agtatcgctc caaccttgcg cgcgaccaat cgtgttaaac atggtcttgc catgacgtac
     4741 caaatacaat cgtactttta ccattttccg tcctccgttt gcttctatta tatcatgaat
     4801 gataaaataa aagccaccca tacaggcgac ttttgaagga gattattatg aaaaagttta
     4861 ggagttcatt aaataaagat attagatgaa aatcaaattc aaactaattc agtgttatct
     4921 gtttcaaata atattaggag gtctttattt aatgattata gtatacacat ctaatcttaa
     4981 atagaactta aaatttctcc tattttctta atttttaaaa ctatgaattg gtgctgggat
     5041 ttgtccaccg cgagagatga agtcgacaga cgaagcccca ttaaccttca taacgggtgc
     5101 agttcctaat agaccaccaa actcaatcat atcgccttct cttcctttgg gaatgatacg
     5161 aacagctgtt gttttcatgt tgataacacc gattgctgct tcatccgcaa tcatagccgc
     5221 aatagtttca gcaggcgtat cttctgggat ggcaatcata tccaatccaa cagaacagat
     5281 agccgtcata gcttctagtt tttctaaatt aagagagcca ttttgcactg cagcaatcat
     5341 tccttcatcc tcagaaacag ggataaaggc accagataga ccaccgacct ggttacaggc
     5401 catcactcca ccctttttaa cttggtcgtt caagagggcc aaggcagctg tcgttccatg
     5461 cgtgccaact gtttctagcc ccatttcctc aaggacacgt gccacagagt ctccaaccgc
     5521 aggggttggt gccaaactca agtccacaat accaaactcc acacccagtc tctcactggc
     5581 catttgacca accaattgac cgatacgagt gattttaaag gcagttttct taactgtttc
     5641 ggctactaca tcaaagctct gtccacgaac tttttccaaa gcacgtttca ccacaccagg
     5701 accagaaact ccgacattga tgataacatc tgcttcccca acaccatgaa aggcacccgc
     5761 cataaatgga ttgtcctcaa cagcattagc gaatacaacc aacttggccg ctcccatatc
     5821 tgaaagattt gccgtttcct tgataattcg tcccatatct gccacagccg tcatattaat
     5881 accagacttg gttgagccga tattgactga cgagcagacc ttatccgtct cagtcaaagc
     5941 gcgaggaatg gaattgatga gaatctcatc tcccttttga taaccttttt gtactaaggc
     6001 agaaaaacca ccaataaagt ccacaccaat ctctttcgca gccttatcaa gcgcttttgc
     6061 cagaaccacg tagtccgtcg catctgtcgc tgccccaatc agagaaatag gtgtcaccga
     6121 tacacgctta ttaacgatag gaattcccaa ctcagccgca atttcatcac caacagctac
     6181 taaattagcc gcctttgtcg taattttttg atagattttc tccgcagcac gattgatatc
     6241 tggatcgata cagtccaaaa gagaaatccc catggtaatg gttctaatat cgaagttttg
     6301 ctcctcaatc atggcgatgg tttcagtaac ttgtctaata tccatgatga cctcctagat
     6361 attatacata gcttcgaaaa tcgctgcact ctgaatattg atttttacat tcaaagtttg
     6421 cccaaaagct tcaaattcat tacgaagata ggtaaaatct tgcttttcat cactagatac
     6481 aacagccatc atcgtaaaat attcatccaa gacagtttga gagatatcgt caatattcaa
     6541 tcctaattct gcaattttac cagaaacacc tgcaacaatt ccagatttat ctttaccaac
     6601 aacagttata atggctttca taagtaaact ccaattcttc ttaaaataag aaaccttaac
     6661 attaaacagg attcttttca aatagtatag cataattcta acgaaaatac tcaaaaacgc
     6721 ctgcttacga agttgttctt aagaaaaaaa caatttcgta aacaagcgtc tactatccca
     6781 acttatgatg agtgttcccg ctaggaccga aatcctagcg gtagaccaga gctagactaa
     6841 gagcacaaga ctccatcatc ataacactca acaaaattga tgattttata ctaattcgat
     6901 gatcgccatt ggcgctgcat caccacgacg tggttcagtt ttaaggatac gagtgtatcc
     6961 accgttacgt tcagcataac gaggtgcgat ttctgagaac aatttttgaa gtgctgtagt
     7021 agaagtgtac ttatcagttg cttcatcata gttttcagat gcgatttcat tacgtacgaa
     7081 agcagctgct tgacgacgtg catgcaaatc accacgttta cctagagtaa tcattttttc
     7141 aacagtttta cggatttctt tagcacgagc ttcagttgtc acgattgatt cgttgatcaa
     7201 aaggtcagtt gtcaaatcgc gaagcattgc tttacgttgt gagctagtgc gtcctagttt
     7261 acggtaagcc atgtattcct cctttattta tcttttaatc caagacccaa atcaatgagt
     7321 ttgagtttca cttcttccaa actcttgcgt ccaagatttc gtactttcat catctctgct
     7381 tcagattttt ctgtcaaatc atgcacagta ttgataccgg cacgttttaa acagttgtat
     7441 gaacgcacag acaagtccag ttcctcaatc gtacgatcta aaatacggtc gtcagattca
     7501 gtatcagctt ctttcatcac ttcagttgac ttagcaatct cagtaagatt tgtaaacaaa
     7561 tcaagatgtt ctgtcaaaat acgtgctgaa agccctaaag catcttctgg aataattgtt
     7621 ccatttgtca agatttcaag ggttaatttg tcgaaaccat cattgctacc tacacgagca
     7681 ggttccactt gatagttgac ttttgtaact ggtgtataaa tagaatctac agcaagtgtt
     7741 ccaactggtg cattatcctt tttattttca tcagcaggta catatccacg accactgtta
     7801 acagtcatag tcgcttttag agaagaacct tcaccaattg taaagagata atgatctaga
     7861 tttacaattt caatatcgct atctgtcaaa atgtcaccag ctgttacttc agcaggacct
     7921 tcaacatcca gttcgatgat tttttcgtct tcaacgtacg atttcactgc aattccttta
     7981 atgttcagaa tgatttgcat cacgtcttca cgaacacctg gaactgtgtc aaactcatgt
     8041 aacacaccat caatgttgat agatgtcaca gctgctcctg gtagagaagc tagaagtaca
     8101 cgacgaagag agttaccaag agttgtaccg tagccacgtt caagtggttc gattacaaac
     8161 ttgccataat ctttattttc atcaattttt gttatatttg gtttttcaaa ctcgatcatt
     8221 tagttactcc ctcttaaacg aaaagcagtg taatgcgatg attatacacg gcgacgtttt
     8281 ggaggacgag caccattgtg tggcactgga gtcacatcac gaattgctgt tacttcaaga
     8341 ccagcggcag caagcgcacg aatagctgac tcacgaccag aacctggacc ttttacagta
     8401 acttcaactg atttaagacc gtgttcttgt gcagatttag cagcagcttc agaagccatt
     8461 tgagcagcga atggtgtaga tttacgagaa cctttgaaac caagagcacc agctgatgac
     8521 caagcaattg cattaccatg cacatcagta atcataacaa tagtgttatt aaatgtagcg
     8581 tgaatatgag caataccaga ttcgatattc tttttcacac gacgtttacg tgttggttta
     8641 gccaagactt ttacctccta tattattttt tcttaccagc aatcgcaaca gctttacctt
     8701 tacgagtgcg ggcgttgttt ttagtgtttt gtccacggac aggaagtcca cgacggtgac
     8761 ggataccacg gtatgaaccg atttccatca aacgtttgat gttcaagttt acttcacgac
     8821 gaaggtcacc ttcaactttg attgcatcca cttcacgacg gatagcatct tcttgatctg
     8881 atgtaagatc acgtacacga acatcttctg agattccagc agcagccaaa attttcttag
     8941 atgttgcaag tccgatacca taaacataag tcaatgagat tactacgcgt ttgtcatttg
     9001 gaatatcaac tccagcaata cgagccatgt tttctccttt ctatcttatc cttgacgttg
     9061 tttgtgtttt ggatttgctg ggcaaattac cataacacga ccattacgac gaataacttt
     9121 acagtattcg caaattggtt tgaccgatgg tcttactttc atttcttatc cctccaagtt
     9181 tttcgattat ttaaagcggt aagtgatacg tccacgtgtc aagtcatatg gactcatttc
     9241 gacagtaaca cgatctcccg ctaaaatacg aatatagttt ttacgaattt taccagaaac
     9301 tgttgctaaa atctgatgtc cattttcaag ttcaaccgta aacattgcat tcggcattgt
     9361 atcaactact ttgccttcaa cttcaatcac atcgtctttt gccacgcaaa agcacctcca
     9421 taaatttcga ttcgatgcct ctagacacag agacaacaat tataagtcag actatctcag
     9481 tataacattt gtagcgaatt tttgcaagta tgaaaaacgc tttatttcaa atttgtcaat
     9541 actttttcaa tatctgagaa gacatcattg atatcttgat taccttcgat gtcatgaacc
     9601 aaacctttgg cacggtagtg agcaatgatt ggttctcctt gagcaatatt aacatccaaa
     9661 cgacgtttta ctgtctcagg cttatcatct tcacgttggt agtaatcttc ttctttatag
     9721 tcaactggtg ggttaaagac cttgtggaaa gtttctccag ttacgcggtg gatgatacgg
     9781 ccactcaaac gttccaagag gctgtcaggg ttcacttcaa tattgataac accttctagt
     9841 tcaatgccaa gttcagccaa tgttttgtcc aaggcatgag cttgttcaat tgtacgtggg
     9901 taaccatcca ataagaatcc tgtttcttta atatcatctt gtgaaaggcg ttcttttacg
     9961 attccatttg taacttcgtc aggaaccaat tcacccttgt caatatatga cttagcaaga
    10021 acacccattt cagtttgatt tgccattgca gcgcggaaca tatcacctgt tgagatatgt
    10081 gcaacatgga attgttctac gatttttgct gcttgagttc ccttacctgc accaggtaag
    10141 cccataatca aaagattcat gatttgatct ccttatttta tttttaaata gaagcaaaaa
    10201 gtcttttcac ccctatttaa aaacaaaata gaagagggga gatccaactc ttacaaatgt
    10261 cagagtttaa acctccactc cctcagcatt tactgattca gtaaatactt ttattctgtt
    10321 ctgtccatga aaccaacata cttacgtttc aataggtaac cttccaattg cttgattcct
    10381 tcgatacctg tagagataat gatcaagaga cttgttccac caaaggcaac aacatcagaa
    10441 agaccaaata catctttagc tgcaatcggt aaaatggaaa tcacaccaag gaagagggaa
    10501 ccaacagttg caagacgacg aagaagttta gacatatatt cttctgtacc tttaccagga
    10561 cgaactccat ggatataggc accactcttt tgtaggctct ctgctgcttt ttcaggatta
    10621 atctgtacaa acgtatagaa gaatgtaaag agaataatca acaaagcata catggcaata
    10681 ccagttggag aagtagttgc caacatctct tgtgctaccc ttacccaagc ccaatcatga
    10741 cctgtggcac tcaaaaactg aagaatagcc gcaggcgctg cagtaatcga actggcaaag
    10801 ataacaggga taactccagc agggtttacc tttaacggaa ggtaagagct agatggagca
    10861 ccttgtgcaa ccttagtata ttggattgga attttgtatt ctgcttgttg aacataagtt
    10921 gtaaagtaaa taatcaacaa tacagtaata atcaaaatga ttacgaaaat gatagatgaa
    10981 gtgatacggc tacttgggac gttcacaaag tagtccacat agatgccctg aatcatctct
    11041 ggaattgagg aaacaatccc ggcaaagata atcatggaaa caccgtttcc gtatccctta
    11101 tctgtaattt gctcacccaa ccaagtgaca atcatactac cagctgttaa gatgatacca
    11161 atcgtcagaa aaacttgtgg agttaaagca gttttaatca attgagctcc agccaaggta
    11221 ttaaaaccag ctgtaatccc gatagattgc acaaaagcga gaactagagc aatataacga
    11281 gtagcttgat tcaattttct tcgacctact tccccttgtt taccccactc tacaaacttg
    11341 ggtaaaatat ccatttgcaa gagttggaca acaatagaag cggtgatata gggactaact
    11401 cctagggcaa aaatcgaaaa gttttttagg gcattccccg acaccaagct caacatgttt
    11461 aagaaggata atccacttaa agcattcaag ctattggcat tcacaccagg aactgtaatg
    11521 ctagttccga tacgaaagac caaaacgata aaaattgtaa ataaaatttt tgatcgaacc
    11581 tgcttgactt taagagcttc tcttaataat ttaaaaaaca taggtcacct ctcttagatg
    11641 acttctactg aaccaccttt agcagtgata gcttcttcag ctgatttaga gaatttagct
    11701 gctttcacag tcaatttctt agtcaactca ccgttaccaa gaattttaat acctgacttt
    11761 tcagctttaa caattcctgc ttcgataaga acaactggag ttacttcagc accatcttca
    11821 aagacgttca attggtcaag gttcacaatt gcgtattctt tagcgttgat gttagtgaat
    11881 ccacgttttg gaagacgacg gaacaatgga gtttgtccac cttcaaaacc aaggcgaact
    11941 ccgccaccgc tacgagcttt ttgacctttt tgaccacgac cagatgtttt accgttacct
    12001 gatgaagtac cacgaccaac gcggttacgt actttacgag aaccttctgc aggtttcaat
    12061 tcatgaagtt tcatttttat tttctcctct tttgtaaaat gctagcgccg ataagggaga
    12121 aaaggttgtc tcccccatca actcgcctat acgatgtcat catagatgac tatatctagt
    12181 tttaggggat ggtacagtgc acatccccta aaacttcatt agtttacttc ttcaactgtt
    12241 actaagtgag atactgctgt gatcatacca cggatagcag cgttatcttc tttaataaca
    12301 gagctgttca atttgccaag tccaagtgct acaacagttt tacgttgtga tggaatgcgt
    12361 ccgattggag acttagtcaa agtaatttta atttgagcca ttttatcccc tttcttatgc
    12421 caaatcagaa actgaaatac cacgaagggc agcaatttct tcagcgcgtt tcaattgttt
    12481 caaaccttca acagttgcac gaacaatgtt gattggagtg ttagaaccaa gtgatttaga
    12541 tgtaatatct gccacacctg ccaattccac aacggcacga actgcaccac cagcggcaac
    12601 tccagaacct tctacagcag gtttcaacaa tactttagct ccaccgaatt ctgaaagaac
    12661 ttcgtgtggg attgttgttc caaccatagg aacttcgatc aagtttttct tagcatcatc
    12721 tactgcttta cggattgctt ctggaacttc ttgagcttta ccagtaccaa atcctacgcg
    12781 accattgtgg tcaccaacaa caacaagagc tgcgaaacga agacgacgtc cacctttaac
    12841 aacttttgta acacggttga cagcaactac gcgttcttct aattcaactg cattgtcttt
    12901 aaatgccatt ttctagtgtc ctcctattag aatttcaatc cgttttcacg agctgcatca
    12961 gccaaagctt tcacacgtcc gtgatataga tatccaccgc ggtcgaacac cacttctgaa
    13021 atacctttag cgtttgcacg ttctgcaacg agtttaccga cagcaacggc ttgttcagtt
    13081 ttagttcctt ttgaaacttc tttatcaaga gttgaagcac ttgcgagcgt tacacccgct
    13141 acgtcatcaa tcacttgagc gtagatgcct gtattagaac ggaatacgtt caaacgtggg
    13201 cgatcagcag ttccagagag ttttccgcga acgcgacggt ggcgtttttg gcggagtttg
    13261 tttttatctg gttttgaaat cacagttttc acctctttag ttttaaatcg tgtgctatgc
    13321 acaaagttgg aaaataggtt ggtggttgat gatcaaccac tcaacattat ttacctgttt
    13381 taccttcttt acggcgaacg aattcaccaa cgtaacggat acctttacct ttatatggtt
    13441 ctggtgaacg aaggctacgt acgtaagcag ctgtttgacc aactacttct tttgaaattc
    13501 cgctaacaac gattgttgtt gggtttggaa gttcaaaagt aattccttct ggagcttcaa
    13561 cttcgtctgg atgagattta ccaacagcca aaacaagttt agatccttga agctgtgcac
    13621 ggtaaccaac cccacgcatt tcaagttctt tcttgaatcc ttctgataca ccaacaacca
    13681 tgttgttcaa aagggcacga gtagttccgt ggatagtttt catttctttt gaatcgtttg
    13741 gacggtgaag agttatttca gtaccttcca cacggatttc aatatctttt gagaactcac
    13801 gagtaagttc tcctttaggt ccttttacag ttacaacgtt gtcattgtta gcgagttcaa
    13861 caccagcagg caacacgata actttattac caatacgtga catgtttatt ttctcctgtt
    13921 aaattgtcag gccagaacgg ccagttttca cggggttcag atacttattt agttcaagag
    13981 ctgaactgaa cacgctctaa gaactgtgca aaatagataa gttggcttgt ttgtaaacaa
    14041 acttctccaa cttcctaatt ttgctttgtt ctttacgagc tttgtatctt gattttacca
    14101 aacgtaagcg ataacctcac caccaacatt cttttggcgt gcttctttat cagtaagcaa
    14161 accttcagaa gttgaaagga tggcaattcc aagtccgtta agaacttttg gaaggtcttc
    14221 acgttttttg tagacacgaa gtcctggttt agaaacacgt ttcaagttag tgataacttt
    14281 ctcaccattt ggtccgtatt taagaaatac acggatgacg ccttgtttgt catcttcaat
    14341 gatttcaacg ttttttacaa aaccttcgcg tttaaggatt tcagcaatcc cttttttgat
    14401 gtttgatgca ggtacttcaa gtacttcgtg tttagcttgg ttagcattac gaatacgagt
    14461 taggaagtct gcgattgggt cagtcataac cattttgttt ttctcctctt actagtagtt
    14521 tgcaagttgc acttgctagt taatacatga tacaaagagc gtaacagcac gagcaaaaat
    14581 agacaattta atgcagaagc aatgctccaa agcaaattgg tctttttttc caaagctgta
    14641 gctcgtgttc aaattggcaa gcccaattga acccgggcta aactctgtgt gaaaaagata
    14701 aactttccta gaaactttag tttcttcgtc aagtttccta tttttacttg gagttttgac
    14761 gctcttgata tcttaaatta ccaagatgct tttgttacac caggaatttg acctttatgc
    14821 gcaagttcgc gaaaagcgat acgactcaga ccaaatttgc ggtaaactga atgtgggcgc
    14881 cccgtaactc tacaacgatt atgtaaacga gtcggtgagg cgttgcgagg taatttagat
    14941 aaaccttcgt agtcccctgc cgcctttaat gcagcacgtt tttcagcata acggtcaaca
    15001 attttttggc gtttagcctc tctagctacc attgattttt tagccattag atttacctcc
    15061 tatattattt tgcaaaaggc attccaaggc ctgtaagcaa tgcacgtgac tcttcgtcag
    15121 tgttagcagt tgttacgata acgatgtcaa gaccacgagt tttgtcaacg tcatcgaagt
    15181 tgatttctgg gaagattaat tgttctttca caccaagtgt gtagttcccg cgtccatcaa
    15241 atgattttgt tggaacaccg tggaagtcac gtacacgtgg aagtgaaact gataccaatt
    15301 tatccaagaa ttcgtacata cgttcaccac gaagggtaac ttttgcaccg atcgcaacac
    15361 cttcacgaag acggaagccg gcgattgatt ttttagcttt agtgataagt ggtttttgac
    15421 ctgagataag tgccaattct tcagcagctt tttcaaggct tttagcgttt gatacagctt
    15481 caccaacacc catgttcaaa acaatcttat ctactttagg cacagccatc actgatgagt
    15541 agttgaattg ttctgtcaaa gcaggaacta cttcattaag atatttttct tttaaacgat
    15601 ttgccattat acttctcctt tccttcgtga ttaatcaagc acttcgcctg attttttgtt
    15661 gtagcgaact tttttaccgt ctacaaattt gtaaccaaca cgaccagcta caccattttt
    15721 gtccaaaact tgaacatttg atacgtggat agctgcttct ttctcgatga taccaccttg
    15781 aggaagctcg ttagttggac gttggtgttt cttaacaatg ttaacacctt caacgataac
    15841 tttgtttact tttggaaggg cagtaaggac aacagcttct gttcccttat ctttaccagc
    15901 gattacgcga actttgtcgc ctttttttac aaacattagg tttctccttg atttttctta
    15961 cgcccataag ggcaccctag cttgaagcta ggggactagt ttgttcctaa aaattaaagt
    16021 acttctggag caagtgacac gatcttcatg aaaccacctt cacgcaattc acgtgcaact
    16081 gggccaaaga tacgtgttcc gcgaggagtt ttgtcttcac ggatgataac tgctgcgttt
    16141 tcgtcaaatt tgatgtatga accatcagca cgacgagcac ctgatttagt acgaacgata
    16201 actgctttaa caacgtcacc ttttttaacc gcaccaccag gagtagcttg ttttacagat
    16261 gccacgataa catcaccgat gtttgcaaat ttacgtcctg aaccaccaag aactttgata
    16321 gtcaagattt cgcgagcacc gctgttgtct gcgactttca aacgagtttc tgtttgaatc
    16381 atttcagttt tctcctttca ggtttgatta gatgatgacc gcttcttcaa caacttctac
    16441 aagacggaaa cgttttgtag ctgaaagcgg gcgagtttcc atgatacgta cgatatcacc
    16501 ttctttggca acattgtttt catcatgagc tttgtatttt ttagagtagt taatacgttt
    16561 accatagact gggtggttac gttttgtttc aactacaact gtgattgtct tgtccatttt
    16621 gtcagataca acacgtccaa caagaacttt acgattattg cgttccattg aaatttctcc
    16681 ttccctagtc tattatttcg cttcagattg aactgttttg atacgagcga tttgtttttt
    16741 aacttctttc aagcgagctg tttgttccaa ttgaccagta gcagcttgga aacgaagttc
    16801 aaacaattct tttttcaatt cgttttcgcg cttcgcgagt tcttcttgag aaagaccacg
    16861 aagttcttta acaaattctt ttacttcatt aagtttcatg ccttctcctt attctgcttc
    16921 acgttttacg aatttacatt taactggcaa tttgtggcta gcaagtcgaa gcgcttcacg
    16981 tgcaatctct tcagatacac cagcgatttc gaacatcact ttaccacgtt taactggtgc
    17041 tacccaacct tcaggtgccc ctttaccaga tcccatacgc acaccgatag ctttagcagt
    17101 gtatgatttg tgtgggaaga ttttaatcca aactttacca ccacgtttca tgtaacgagt
    17161 catggcgata cgagcagctt cgatttggcg gttagtgatc cagtggctag ttgtagcttg
    17221 aagaccgtat tcaccgaatg ctacttcttt tccacctttt gcttcaccgc gcatttttcc
    17281 acggaattca cgacggtgtt taacacgttt aggtactaac attggttatt tacctccttt
    17341 agtgttttta cgagctggaa gaacttcacc acggtagatc catactttaa caccaagttt
    17401 accgtatgta gtatctgctt cttcccaagc gtaatcgata tctgcacgaa gtgtgtgaag
    17461 cggaacagtt ccttcagagt agccttcagc acgggcgata tctgcaccgt tcaaacgacc
    17521 tgatacttga gttttgattc ctttagctcc agcacgcatt gcacgttgga ttgcttgttt
    17581 ttgtgcacga cggaaagcaa cacgttgctc caattgacga gcaattcctt cacctacaag
    17641 gtgagcatcc aaatcaggtt gtttgatttc gatgatgttg atgtgtactt gttttccagt
    17701 caatttgtta agttttgcac ggagtgcatc aacgttagca ccacctttac cgataaccat
    17761 acctggttta gcagtgtgaa gtgaaacgtt aactttgttt actgcgcgtt cgatttcaat
    17821 agttgaaact gctgcgtcag caagttcttt ttgaacgaat ttacggattg caagatcttc
    17881 atgaaggtaa tccgcgtatt ctttttcagc ataccatttg gcatcccaat cacggatgat
    17941 gccgacacgc ataccaattg gatgtacttt ttgacccacg attttacctc cttatttttc
    18001 tgcaacagct acagtgatgt gagctgtacg tttgttgatt ggtgaagctg aacctttcgc
    18061 acgtggacgg aaacgtttca tagttggtcc ttcgtttgcg aatgcttcag atactaccaa
    18121 gttagcttta tccaaaccaa agttgttttc agcgttagct acagctgagt tcaaaacttt
    18181 caagatgatt tcagcagctt tgtttggagt gaatgtcaag attgcgattg catcggctac
    18241 gcttttacca cggatgttat caagaacaag acgtgattta cgaggtgaaa cacgtactgt
    18301 acgagccatt gctttagctg aagtaatttc tgccatttat gttctcctta ttttctacgt
    18361 gttttcttgt cgtctgcagc gtgacctttg taagtacgag ttggtgcaaa ttcaccaagt
    18421 ttgtggccta ccatgtcttc ttggatgtaa acaggtacgt gtttacgtcc gtcataaact
    18481 gcaatagtgt aaccaatgaa acttgggaag atcgttgatc gacgtgacca agttttaata
    18541 acttttttct tttcgtcgtt agcttgagct tcaacttttt tcatcaaatg ctcatcgacg
    18601 aaaggtcctt ttttaagact gcgtcccatt tttatatttt ctcctttaaa tgttgtacca
    18661 cagcggcttg cactcctatg gagcgctacc gagctggcgg atttactagt tgcttaagcg
    18721 actagtttaa tattatttct cgttgcgacg acgaacgata agtttgtcag atttcgcttt
    18781 cttgttacga gttttaagac caagagcagg tttgccccat ggagtagatg gtgctttacg
    18841 accaactggt gctttacctt caccaccacc gtgtgggtga tcgttagggt tcattacaga
    18901 accacgaact gttgggcgga tacctttcca acggctacgt cctgctttac caaggtttac
    18961 aagtccatgt tgttcgtttc cgacaacacc aactgtagca cggcaagttc caagaatcat
    19021 acgaacttca cctgattgaa gacgaacaag aacatattta ccttcagaac ccaatacttg
    19081 agcagatgca ccagcagcac gtaccaattc accaccacga cctggtttca actcgatgtt
    19141 gtgaatcaaa gtaccaactg ggatgttagc aagtggaaga gcgtttccga ctttgatatc
    19201 tgcttctgga cctgaaacga tacgttgacc tacttcaaga ccttttggag cgatgatgta
    19261 tgctttcaca ccgtcagtgt agtgtacaag agcgatgttt gcagaacggt ttggatcgta
    19321 ctcgattgtt ttaacaactg cttcaacgtt gtctttatta cgtttgaagt caaccaaacg
    19381 gtagaaacgt ttgtgtccac caccttggtg acgaactgtg atacgaccgt tgttgttacg
    19441 accagccttg ctcttcaatg caacaagcaa tgatttttca ggagtgcttg ttgtgatttc
    19501 agcgaaatcc aaagaagtca tattacggcg accgtttgtt gttggtttat aaacacgaat
    19561 tcccacgata tttcctcctt agattattca gcttcagcag caaacaactc gattgcttta
    19621 gaatcagctg taagtgtgat gatagctttt ttagttttgt tagtaaaacc agtgtaacgt
    19681 ccaacacgtt tagcttttgg ttttacgttg attgtgttaa cattggcaac tttaacacct
    19741 tcgaaagcag cttcaacagc ttgcttgatc aaaagtttgt gtgcacgagt gtcaacttca
    19801 aatacatatt tccctgcttc aagttgagcc attgagcttt cagtgatgac aggttttttg
    19861 ataacatcat acaaattcat tatgcaagaa cctcctcgat tttagagata gctgcttgtg
    19921 tgacaagaag tttgtcgcta tttgcgatgt caagaacact tgcagttgta gcagttgcaa
    19981 ctttcacgtt tggaaggtta cgagctgaaa gagctgcgaa ttcatttcct tcttcaagga
    20041 taacaagaac tttagaatcg atgctcaatg ctgcaagaac ttttgcaaat tcagcagttt
    20101 ttggagctgt aaatgaaaga gcgtctacag ctacgaattt gttttcagca actttttcag
    20161 agtaaactga tttaagagct aggcgacgaa ctttttgtgg aagtttgtag ccgtatgaac
    20221 gtggagttgg tccgaagaca acaccaccac cacgccattg tggtgagcgg atagaacctt
    20281 gacgagcacg tccagttcct ttttgacgcc acggtttgcg tccaccacct gatactgcag
    20341 agcggttttt aacagcgtgt gttccttgac gaaggcttgc gcgttggctg atgattacat
    20401 caaacacaac tgattcattt ggttcgatac caaatactgc atcgttaaga acaacttggc
    20461 cagcttcttt accagtttgg tcaaataatg ttacgtttgc cattgtgact gatttcccct
    20521 ttctttatta tttaccagct ttaactgctg atttgatagt gataagagat ttcttagcac
    20581 ctggtacgtt acctttgata aggataacgt tcttttctgg aacaacttgt acaacttcaa
    20641 gattttgaat tgttacgcgg tcaccaccca tacgtcctgc aaggttttta cctttgaata
    20701 cgcggttagg tgcaacaggc cccatagaac ctggacgacg gtggtaacga gaaccgtgag
    20761 ccattggtcc acgtgattgt ccgtggcgtt tgataacacc ttggaaacct ttacctttag
    20821 aagtaccagt tacatcaaca acatctccag ctgcgaatgt ttcaactgtg atttcagcgc
    20881 caacttccaa gccttcaacg tttttgaatt cacgaatgaa gcgcttagga gccgtgttag
    20941 ctttcgctac atgtccttta gcaggtttgt tgctcaatac ttcgcgtttg tcatcgaaac
    21001 caacttggat agcgttgtat ccgtctgttt caacagtttt aacttgaaga acaacgtttg
    21061 gagttgcttc aataactgtt acagggatca attcgccagc ttcagtgaag atttgagtca
    21121 ttcccacttt tttccctaag attccttttg tcatgagaaa atagttcctt ttctatattt
    21181 tttattcaaa aagtttttaa cgagcgtttt ttatgctcaa gtctaagata caaagggcgt
    21241 caaactcaaa gtgaaaatag gaaactaacg cagtgtctaa cggacaatag gaagtttatc
    21301 tttttcacac cgagtttagt ccgtgttcaa ttagattgaa acaccagcct ctgctctttt
    21361 atattttaga ttaaagtttg atttctacgt ttacaccact tggaagatcc aatttcatca
    21421 aggcatcaac tgttttttga gttgggttaa cgatatcgat caaacgtttg tgtgtacgca
    21481 tttcaaattg ttcgcgagag tctttgtatt tgtgagtcgc acgaatgatt gtgtagaggc
    21541 tacgttcagt tggaagtggg attggacccg caacttgtgc acctgtacga gtagctgatt
    21601 ctacgatttt tgcagccgct gtgtcaagcg tacggtgttc gtaagctttc aaacggatac
    21661 ggattttttt gtttgccatc tttttctcct tttcgtctat ttaagataat aggctagctc
    21721 cacaagaaaa ccgacacggt gttgcgtggc aatgcaaccg agcgtgtcgc aacctcttgt
    21781 atcaaaacta aggctgtaat ttacagcacc ataatagaat aacacaaatc ccctgcgatt
    21841 gcaagggatt tgttaggttt tttcgttttt ttgggatgaa actgttttcc tactttttct
    21901 tcctaaaatt agggattttc ttctatattt cttctataca taagttaagt cctcttgaca
    21961 tcaaatttat cttctgattg atccactaag atatccgcct tagactcagt ttctttatag
    22021 tatcgcagat actgctcccg tctcatctga tggctagcca atataaagga tgcatcacga
    22081 tttctcacag tcgtatctct agcaaggcgt cgctttaatt cggtctcctc atccgtgtag
    22141 aaacagatgg ttttttcaaa gagttccttg ggtagaaagc caacagacat cccttcgaca
    22201 atcaaaattg gtttggctcc agacaagacc tcactagcct tccaaggttc ttcaattgtc
    22261 aagacatcca tacccgcctg caaggcaagg atatctctct gcaaactctc cagttcatgc
    22321 gccactggca gactggctgt caccttttga ttcggcgcgt ccttgggtac taccagatgg
    22381 cgtcctgagg tgatataagg atctgtctct agcaaattta ctgtagtaga atctaaagct
    22441 tggtacaatt cctgtgcaaa ggttgattta cctgaagctc catgaccgta tattcccagt
    22501 gtcctgactt tccccgtctc gatctctgag actagttggt ctactaagtc ctttttcttc
    22561 attctctctt cacctgttca tagctttctt ttccgtcatt gagcttgtcc caaatcacta
    22621 cttgcccact tttgagcgat ttttgcacat cgataattcg ttggttagac gaacctcgaa
    22681 actggagcat aagatttctc ttagttcgat catatcttcc atcgacaaga atgtcaatca
    22741 gtgacaagag ttccagttta tctggagttt ccaacatcat ttcttcccaa gtgtagccgg
    22801 tccaggacca aatgtccttg tctggcaatt cctttcggat gcgtttaact agaggcaaga
    22861 gaatgccagt attaagaaaa ggctcccctc ccagcaaagt caagccttga acatagggtt
    22921 gggcaaggtc tgccataatc tgctcttcta attctgctgt atagagaatg ccagcattaa
    22981 aagaccaagt cgcaacatta taacatccct cgcagtgaaa catacagcct gatacataga
    23041 gagagttacg cacgccttcg ccatcaacaa agttaaaggc cttgtagtca atgatacgac
    23101 cttgactaag ttcctcgctt ttccattctt gtggttttgg attattcatt cgctacctct
    23161 atccaataac gctcgactcc attgtgagca tcctcaaata ttccaccatt tgctagaatg
    23221 actgctctgc tagcaggatt attcacgcta caggtcacca gagctttctt gatgttcttt
    23281 tccttagcaa cttgcaagcc ctgacggaga gtctcttttg cataaccctt gcctctttca
    23341 gatggacgga tggagtagcc aatgtgccca ccttcttcta gtagaaagtt actgaggcgc
    23401 aaccggagat taagaaatcc aactgcttga cctttctcag aaaaagccac taactgaatt
    23461 gcaggaaccc atccttcagg cagattaatc cccatttcct gttcctgatt gctttccaac
    23521 cactcttcat acacaaaatt ctctgtatcc caaaatcctc catcatgggc tgattggctc
    23581 ttttcaaact ctgtcatcat atctaaaaca gctttcttat ccgctaatct tggtctgcgt
    23641 aattccatcc ttacctccca ctatgagaaa agcgagagct ggctctcact tttatttttt
    23701 cttgttcttg tttaaaaatt gttctctgaa gctaagcaag cgttctttct taccagctcc
    23761 acctttagag tgtttctcgt gataacgggt cacttgtgcg cgccccttat cgtctagttg
    23821 atattttccc atttcatttc tttctaattt gttacttgat gcccagctat tttaatcgtt
    23881 gaaccattca tatgtttgac acgcgcagcg atttccttgt gacgcccgtt gaccatcggt
    23941 cttgcttgag gattacctag gtagccacaa gttcgcttca ccacatctac tgttttaggg
    24001 tcgctattgc cacagtttgg acaagcaaac cctctctcag ttggttcaaa atccccttca
    24061 aagtcacact tgtagcaacg gtcaatcgga gtattggtgc ctagatagcc tacacggtca
    24121 taagcataat cccagacagc ttccaaggcc tttggatttt gctgaaggac tggatactca
    24181 caataatgga tgaaaccacc tgacgcacct gcttctggat agactttctc aaagtccaat
    24241 ttttcaaacg gtgttggatt tttacgaaca tcgtagtgga aagagttggt gtagtattcc
    24301 ttgtctgtga tatcaggaat agagccaaac ttgtctatat ctagtcggca gaaacggtct
    24361 gtcagacttt cggatggtgt tgagtagata gagaaatggt agccatattg gtctgaccac
    24421 tcttctacac ggcgtttcat atcgtgaatg atgtctagcg tgaattcctt agcatctgga
    24481 ttactttccc agctgttacc aaagaaaact gtcgctactt catacaagcc gatatagccc
    24541 agcgaaacgg tcgcacgacg attcttaaag agctggtcaa cactttcttc tttacctaga
    24601 cgatggccaa aagcaccgta ctgataaagg ataggagcat tcgctggtgt cgcctcttta
    24661 gtgcgttcga cacggtaaac aagagcatct tctgcgatat tcattcgctc gttgaagatt
    24721 tcccagaact tattcatatc accttcagac tcaagagcaa tacgaggcag attaaccgtc
    24781 acaacaccca gattcatgcg acctgaattg acttctacac cattttcatc cttccatcct
    24841 tggaggaaag aacggcaacc cataggcacc ttgaaggatc ctgtcaagtc aacaatctta
    24901 tcgtaagata aaacatctgg atacatccgt ttggttgcac actcaagagc caactgcttg
    24961 atgtcgtagt tgggagttcc ttcctctaaa ttaaggcctc ttttcagagt gaaaataagt
    25021 ttaggaaaga tagccgtacg gtgttctgaa ccaagaccct tgatgcgaat gtttaaaata
    25081 gctttttgaa tttctcgttc aaaacgactg gttcccagac caaaacctag cgaagtaaaa
    25141 ggtgtttgtc catttgaagt gaagagagta ttgatttcat actcaagaga ttgcatggca
    25201 tcgtaaatgt ccttttgcgt tttcttccaa gcgtaatctt cccgtttttc aggcaatacc
    25261 cactcttctg catctttgag atgtttttga tagttcttct ctgcataagg cgccaaaatt
    25321 tcatcgatac ggtcagctga acagccaccg tactggctag aagcaacgtt ggcaatgatt
    25381 tgagaaatct gtgctgtcgc agtctggata gacttgggac tctctacctc tgcatttcca
    25441 atcttaaaac cattttccaa cataccctta aaatcaatca aacagcagtt ggtcataggg
    25501 gtatagggac tgtagtccaa atcgtgatag tggatatccc ccttttggtg ggcattggct
    25561 acgtgcttag gaagcatttg cagtccgatt gatttcccaa caatccctgc tgtcaaatca
    25621 cgctgagtgt taaagacatc actgtcttta ttagcatttt cattgacaac tgtctggtct
    25681 ttgttgagaa gtttatgaat actaaagttg atatccgtcg cttttgagcg ctcaaaatcc
    25741 ctctgtgtcc gataagtaat atactcctca gccagcgcat attctttggc ttcaaggagt
    25801 tcatgttcta cgatattttg aatttcgtaa atcttaattc cctgtggaaa gcgactatga
    25861 atttctgtaa taattctctc agtcagatca ttgaggcgtt tttcaaccag gggtgtcaca
    25921 tccataacct tgtcagctgc cttgtggaga gccttgtcaa tcttgtccac atcaaataca
    25981 acacgtctcc catctcgttt ctcgacgaag agagttggca aaattgtaat tttttcttct
    26041 agtgcaatca tatgcatgct cttttctaaa atgttctttc taaaaagtat tataccactc
    26101 taaaaagaaa aatcaatatc ttgtgttaaa aatcttaaaa tttttaaaaa tacacaagat
    26161 attgatttgg ttatttaatt ttatagactt taaactctga gtaatcagtc tttacttgtt
    26221 ggtaattttc ttttaagagt gtttccactt cagaccagac ttccaccttg tcatttacca
    26281 caatcacctt aggttgtttt tctttcaagt cattaagtaa cttattacga ttttcctcag
    26341 ttgctgtata gtgcaacggg gacaaaatcg ccgatggcga caagcgctca ctcttacgat
    26401 aaagagtcgc agtatcatcc catgcataga tagcatcttc cgtatttgtc tcctctttta
    26461 ccaaatcagc aagacgatta cgttcttgat aaggtactgg ataaaggaca aacttcatca
    26521 aaaaaggaac agacaaaaga tagacaaacc caaaaacttg cagatataga tttcctttga
    26581 agaaacgact ccataggcta actggcgttt ctcttcggct tcttctagca ctacgccccc
    26641 tctgttgact cttaatattg gttaccaata aaagtaggaa aacagggaag acgaccatca
    26701 aataagaagc gtgcagaggc tcttgtgaaa agaaaagtaa aatcaaacct aaaattacca
    26761 caagacttgc aggaaccgaa atgacgtata gtttaaaggg tttggattga aagagaccta
    26821 aaaagataca aaccacaaat cccaaaccaa gggacaacaa gccataaaaa aacatattct
    26881 ctaaaatttt agaagtaaaa tcaaagcgaa tactgtcaat aggataacga ataccactaa
    26941 tcgcatcccc aaaacttcct gttgcagcac tatagtaggc agttggataa aagacaagtg
    27001 aaaaacctaa agccactgca agaaactgat aaaacccatg cgcaaagcgt ctatgcccaa
    27061 ggttaaagac caacaagcct aaactcacta cagcaataaa caggagcgat gataagggag
    27121 caaagaaaaa tccgcctgcc aaagctagcc caatccgtac aaatccctta tcatggcttg
    27181 gattgcttag gtaagccgca actaaactaa aggctgcgaa taagaaagga agcgctaaaa
    27241 gagtcgcata gcctccacca aaagcaagac ctgtaactag catgtaaaaa atagtcacca
    27301 gatgtccagc ttggtctcct tgctctgtca aggtgtccgc tgatctaaaa aggaaaaatc
    27361 ctcctgctac caaggctaac cactcaaaga tggcaaagaa aaatccgccc tgactcacgt
    27421 aagtcagcaa ataataaagc aaaccttgac ttccataata gtcgctgtaa atcttccctg
    27481 tctgatgaag cgcccaacct gcataaaaat cctgcacttc ttgtgcactc attaagtcga
    27541 gtaatagcgg tactcctaga gttatccccg ttacaagcgt actccatagt aaaattttca
    27601 ccaaaggaag acgacttgat tcacgatgat gcgattcttg ttcgatttgg tattctagag
    27661 gttcacgatt ctccttatga acttcttcta ctctaccata cacactcata tcgtttctcc
    27721 tgttcaattt atctgtctta gtatatcaaa aagtcctagg attgtcagct tgcgatggct
    27781 gtttgagtga ttttttgcat agtttcacaa aggtttcaat ttcccgaaag cggtgtaaat
    27841 gtgtctgttt gaactcaatc atatcattca cttcttcctt agttagcatg aattcccctc
    27901 ctctttcttt ctattcgtaa aagacaagaa aaataggtct ggtttgtatc ctaagttcta
    27961 gatttcttat aagatagggg cgaatagctg ggcgatttct tttacaagct tttgatacca
    28021 gctcgttttg atagaatgag gatagacttc ctgagaatct gcaaatatat ttcgaaaatc
    28081 tcgggcgatt tcccttatag aaggagtttt atagagtaag actgcatttt cataatggtg
    28141 taccaagctc cggtagtcga gattgattgt ccccaccacc gcaaaatctt cgtctaccaa
    28201 catctgctta ctatgaataa aacctggact atactcataa atccgaacac cagcagaaag
    28261 aaggtcggga taagctcctc tcgtgactaa ctgaatgaac ttcttatctg gtatgtaagg
    28321 ggtgataatt cgaacatcga cccctctcat agctgcattt ttgattgtct ctgttaaatc
    28381 ataatctata atcaaataag gtgtcgtaat atagaccgat tctgttgctt gattgattaa
    28441 actctgataa acttttttcc ctacctgcgc tcgaaaaatt ggcttgggtc cacttccgta
    28501 tggaatggtt aaaccgtcac tcgggataga atgattttct aaatgatatt gatcaaaatc
    28561 actaatttct cctcgattaa tgtaccaagt ggtcaaaaat aagcgtgtca gagcttttac
    28621 tgctagtccg tctaagcgaa ttccactatc cttccaataa ccaaatctct cgacgtggtt
    28681 aatgtactca tctgccagat tgatcccacc agtataggct atctgaccat caacaatcaa
    28741 tatttttcta tgatctctgt tattataagc cactgtcaaa cgaggaataa ctttattgaa
    28801 tttatgggcc tcgatgccca gctgacgaag tcgatgtgca taatctcctg ttaaagtagc
    28861 catacagccg atatcatcat agagcatctt aacctctaca ccctgagcta ccttttgctc
    28921 tagtatatct agtatgcgat tccacatcaa accttcttct ataatgtaat attccaagaa
    28981 aataaatttc tcagcctttt taagatcttc taccatcttt ttccacatag cttctccgtt
    29041 aggaaaaaat gtagaggcag tttgatcata gatgtcagca ttggtatcca tactcaataa
    29101 ggacttgatg actccataag ctgccttgtc actttctttt aatttctctt ttagtagctg
    29161 gctatttgct tcttggaaat gcatagagcc tagcttcttc agttgtttga tttctttttt
    29221 ggacaatcgc ctttcaccaa acatcagata gagcaaggga ccaaatactg gcacaaaggc
    29281 tactaacaac caggttacct tattctcagg agtcgtatta cggttgacta tcgaaatgat
    29341 tgtgatgata ctcagtagaa tgaggacagt aatccataaa atgggagcca tgcgtcctaa
    29401 ataaagaaag agaccaaaaa caagacaaag ttcaagtagc ataatcgaaa gactaaagcc
    29461 atacttggac atcaataatt gaaatttcct atatttcata tcccctcctt gatagtttga
    29521 atgctaaaaa caagtaattg atactagtat aacgcaggta ttcggtagaa ggcaagtatt
    29581 tatgattatt ttctaggtaa aagtaaaaag gctgaaaaat ccagcccttt ctacttgcat
    29641 agtcttattt agttaaaacg atttggtccg atgggtctct atccatatca tctacgacga
    29701 tttgattacc gtttacagtg taaattttga catcatcgcc aataatcatg cgttgatttg
    29761 ctgaatcaaa tgtaacctgt ttgactttct gatccccgtc agattcgagc tcagtccatg
    29821 taccagtcgt tccagttacc actaaagtga tacggtctcc gtcatcctga ccagtataag
    29881 tcccatcaat atcggtcggt tgagcaacag gttggttttg tactggagcc gcttgatttt
    29941 ggttacctcc tgcatttgca gtattggtat tctgttgagc aggctgttga acctgttgag
    30001 ctctttgtga acaagctact aagagactaa aacttgctag agaagcaaga gaaagtgtga
    30061 atctttttaa tttcatgatg aatttccttt ctgctaccaa tttagagaaa ttttctctaa
    30121 ccagcaattc ccctagtata acaagttcaa acaagggggt caatttatct gctcacggtc
    30181 cagcaggtag ccccgtactt ctgagataaa atagagagac cctgtaacga acagcaaatc
    30241 ctgagcatct gctctttctt caaaatcgct gataaattct cggtaagaag aaactatatc
    30301 gtaacctgtc acatcccttt cgtccaaagc cccctgatag tcaaagccgg tcaccttgag
    30361 ttccacctga ggcaattttt cagtcaggta acctaacatc ccttgataat ccttccgttt
    30421 caaggctcca aaaaggattt gaggacgata accttcctgc tctttttctt tgataaactc
    30481 aaccaagcga gtcaaggcag ggaggttatg agcaccatcc aagtaaatct gtgggcgaat
    30541 acgctccaag cgaccagccc aatgggtctg ttccaaggcc tttcttacag cctgttcatc
    30601 aacagcttcc tttccttctc ccataaaaag aagaaaagtt tgcaacgcca aggctgcatt
    30661 ctcctgctga tagactcctt ctaagcctat gttcagctgt gaaagattta gtaaagagct
    30721 tgaaaaatca ccattcagca ttaaaaaatc ttgacctgcc tgataaaggt taacagctaa
    30781 agattcggct tttttctgac agacaagcct agcttctgga ggcaatttcg caatcactgc
    30841 cttcttacca gccttgaaaa taccagcttt ctgctctgca attgcttcta gactatcacc
    30901 caaggtttct tgatggtcaa gcccaatgga ggtgatgaca gcaagctctc cagttaccac
    30961 attggtcgtg tcaagtaagc caccaattcc cacttctaat aaaaccaaat ccacctcctg
    31021 ctccctaaaa taaagaaaag caaccaaggt cagcaattca aaaaaggaca actggtcagg
    31081 agtttgcaga agcgttttct ccatctcctt gacctgatca gccaaacgga taaagtctgc
    31141 gtctgctata ggttgcccat taatgcaaat tcggtcattg atggatacga tatgagggga
    31201 ggtaaaggtc gcaacttttt tgccatgccc cataaataat tccctcataa aagcaatggt
    31261 agatcctttc ccattagtcc ctgttacgtg gataataggg taagactgct caggatttcc
    31321 taacaaatcc accgcttgct gtattcggcc caaacctgat cgaaaattca aaccaatccg
    31381 actatgaagc cattcttcta cttcaaacat acacatctcc ttgacaaaag tccaatcaat
    31441 tatcgcatta aagtatagtt actaataaaa acaaggccag gattttcgtc ccgacctctt
    31501 acctggttag ctaataacta gctactatga atgtgaacgt gggctaaaaa tatccactag
    31561 atgttccaac tcttctcaat ttctaggagt tggggtaaaa atgttcactg gacgttccaa
    31621 ctcttcccca tttctgggag ttgggctgat acagtctctc agactacctg cgtttctaat
    31681 ttctagcgca gggctaaaaa cgtcccccgg acgtttttac tcctccataa agctgttgaa
    31741 gacttcttca atcatgttcc attcgtcttc tgagtcttct gggattggtt gcaattcgcc
    31801 ttctgttcca tcttcgtttt cgatgaatga gtaagcttgg atttcaactt gtccgtcttc
    31861 gtcttcttct gcgttaactg gtactagaag aacatagttt ttaccaaatt cttcttttcc
    31921 atcaattgtc aaaaggattt caaacaaggt ttcatttcct tgctcatcta ctagtgtgat
    31981 tagttcacgt tcttcgtggt cgtggttatg atcgtgtgac atagcctctc ctttatatta
    32041 aaattttcta tctaaataat tttgtaaaat cagctgagct gctaacttat caatgacttt
    32101 cttgcgctta ttgcgactga tatctgcttg ttcaatcaac atgcgctcag cagccactgt
    32161 tgtcaagcgt tcatcctgat agtctactgg taaaccaaaa aactcttcta gctttgctcc
    32221 gtaggcttga ctagcttcta cgcgcggtcc acttgtattg ttcatgtttt taggcaagcc
    32281 cactacaaat cgttccacct tgtaagtatc aaccaattcc ttaacgcggt caaaaccaaa
    32341 ttggccttgt tcttcattta tctggatgat ttcaagccct tgagctgtaa aaccaagcgg
    32401 atcgctaatc gccaccccta ccgtttttga accgacgtcc aatcccataa ttctcatagg
    32461 ttatagatcg actccttgtc ctttgaggta gtagcgaacc aattcctcaa cgatttcatc
    32521 acgctcatac ttacggattt gatttcgtgc attattataa cgaggaacgt aggcagggtc
    32581 tccactcaat acgtaaccta cgatttggtt aattgggttg taacccttat cgttcaacga
    32641 agcataaaca tctgtcaaag tttcgctaat ttctttttta ttggaatcgt ccaatttaaa
    32701 acgtactgtt tcttcagtaa atcccattct aacaccctct ttccttagaa tagtaccatt
    32761 atagcataat tccttacctt ctacaattca ggcagtctat ttatttggat tttctactgt
    32821 tctgtcgcac catttgccaa tctgtctgaa atatagttgc ttggttcatt tttcaaaaga
    32881 ttttccaaac caatattctt cagatgttcc aactgggaag ccttcttgac atccagaact
    32941 tgaaaatcaa aactagtcgt tgtttgaagt tccgttgcgc tcaatagttt tgtttcaagt
    33001 ttgaaaccta ccaatttacg agcttcaatg atagacttat ccttctcctc cgcttcaaga
    33061 agagcttttt gagtttcttc cactccatgt tggtcaatat aagtcttcaa ctcatcagaa
    33121 actggacgtt tttgttgaat cgttaagctc aaaaaagtct tgtccttgta tgtaatggtt
    33181 tgagtttgct ggctaccatc atctgacttg ggcaagacca aagtcttagt tacaactgta
    33241 ttcttctcag cattttcaat aactggcaat gccgactgaa gcgtatcttt ttctgttttt
    33301 gtagctggtc cagtttcttt tttctgtccg caaccaacca ggacaaaaag gaaagctaga
    33361 ctaacaagaa ctattttttt catttctttc ttctttcttt ttgaaattaa aatagaataa
    33421 gactgggaag tgctcccagc cttgatgttt atagagctgc acgcaaacgt gcttctgcat
    33481 tttctacatt acggacagag cgtggtagga aggcacgaat atcgtcttcc ttgtagccaa
    33541 cttgcaggcg tttttcatct acaaggattg ggctctttaa aattctcggt gtttccataa
    33601 tcagattgag aacttcattg acactcaaat cttcaatatc cactccaagg gctttggcat
    33661 agcgattttt agacgaaacg atgctggcta ttccgttatc tgttttggtt agaatatcca
    33721 gtaattcttc tctcgtaatt ccttctttac caaggttttg ttctttataa cttaactggt
    33781 gggcattgag ccaggttttt gcttttttac agctagtaca acttgagact gtataaattt
    33841 taatcatgta cctacccctt tcgctacatg ttactatcag tttagtctat tataccataa
    33901 aaaacatccg acttgcgacc tatttttaat ttt
//
LOCUS       DAVKBC010000020        32000 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVKBC010000020 DAVKBC010000000
VERSION     DAVKBC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32000
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.020"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..261)
                     /locus_tag="VWX64_001106"
     CDS             complement(<1..261)
                     /locus_tag="VWX64_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9190585.1"
                     /translation="MQDNYTTKGKHLTIDSRSLIERWKKEGKSNREIASLLGKAPQTI
                     HTKIKRRTVRKCLGKGRFKEVYSADYAQQSYENNRKHSVKRSS"
     gene            complement(706..1104)
                     /locus_tag="VWX64_001107"
     CDS             complement(706..1104)
                     /locus_tag="VWX64_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190586.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            complement(1432..1914)
                     /gene="greA"
                     /locus_tag="VWX64_001108"
     CDS             complement(1432..1914)
                     /gene="greA"
                     /locus_tag="VWX64_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU9190587.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(1985..3640)
                     /gene="mltG"
                     /locus_tag="VWX64_001109"
     CDS             complement(1985..3640)
                     /gene="mltG"
                     /locus_tag="VWX64_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU9190588.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLIKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(3721..4215)
                     /locus_tag="VWX64_001110"
     CDS             complement(3721..4215)
                     /locus_tag="VWX64_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190589.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(4212..4676)
                     /locus_tag="VWX64_001111"
     CDS             complement(4212..4676)
                     /locus_tag="VWX64_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190590.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEETLLYVTSQGYSMIWFNPFYLEEQ"
     gene            complement(4686..6020)
                     /locus_tag="VWX64_001112"
     CDS             complement(4686..6020)
                     /locus_tag="VWX64_001112"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU9190591.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(6031..6648)
                     /locus_tag="VWX64_001113"
     CDS             complement(6031..6648)
                     /locus_tag="VWX64_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9190592.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(6696..9800)
                     /locus_tag="VWX64_001114"
     CDS             complement(6696..9800)
                     /locus_tag="VWX64_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9190593.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINRQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADTNLFAFTVTEYLDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKVLPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDVDLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQKLGQFELKDGTLQARKSLAYSLAHLFEGRDRDRVSFSQEFQNLAQ
                     DLTHPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFL
                     TSQVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADSHQIYVT
                     SYATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENH
                     LGELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVY
                     KNELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMED
                     YQGASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPA
                     KERQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHR
                     MGQEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGIS
                     EAST"
     gene            complement(9893..11059)
                     /locus_tag="VWX64_001115"
     CDS             complement(9893..11059)
                     /locus_tag="VWX64_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9190594.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHSRINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(11067..12161)
                     /locus_tag="VWX64_001116"
     CDS             complement(11067..12161)
                     /locus_tag="VWX64_001116"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9190595.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDRADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(12318..14000)
                     /locus_tag="VWX64_001117"
                     /pseudo
     CDS             complement(12318..14000)
                     /locus_tag="VWX64_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768988.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(14172..16130)
                     /locus_tag="VWX64_001118"
     CDS             complement(14172..16130)
                     /locus_tag="VWX64_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9190596.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAVDKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(16333..17955)
                     /locus_tag="VWX64_001119"
     CDS             complement(16333..17955)
                     /locus_tag="VWX64_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9190597.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTTKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            18061..19506
                     /locus_tag="VWX64_001120"
     CDS             18061..19506
                     /locus_tag="VWX64_001120"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU9190598.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLCLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(19552..19746)
                     /locus_tag="VWX64_001121"
     CDS             complement(19552..19746)
                     /locus_tag="VWX64_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9190599.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(19847..20455)
                     /locus_tag="VWX64_001122"
     CDS             complement(19847..20455)
                     /locus_tag="VWX64_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU9190600.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDHL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            complement(20480..20992)
                     /locus_tag="VWX64_001123"
     CDS             complement(20480..20992)
                     /locus_tag="VWX64_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU9190601.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(21078..22013)
                     /locus_tag="VWX64_001124"
     CDS             complement(21078..22013)
                     /locus_tag="VWX64_001124"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU9190602.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(22084..22383)
                     /locus_tag="VWX64_001125"
     CDS             complement(22084..22383)
                     /locus_tag="VWX64_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU9190603.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(22373..23122)
                     /locus_tag="VWX64_001126"
     CDS             complement(22373..23122)
                     /locus_tag="VWX64_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU9190604.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(23176..23535)
                     /locus_tag="VWX64_001127"
     CDS             complement(23176..23535)
                     /locus_tag="VWX64_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU9190605.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(23537..24937)
                     /locus_tag="VWX64_001128"
     CDS             complement(23537..24937)
                     /locus_tag="VWX64_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU9190606.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(25232..25471)
                     /locus_tag="VWX64_001129"
     CDS             complement(25232..25471)
                     /locus_tag="VWX64_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU9190607.1"
                     /translation="MAQQHRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(25503..25973)
                     /gene="ssbA"
                     /locus_tag="VWX64_001130"
     CDS             complement(25503..25973)
                     /gene="ssbA"
                     /locus_tag="VWX64_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU9190608.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(25985..26275)
                     /locus_tag="VWX64_001131"
     CDS             complement(25985..26275)
                     /locus_tag="VWX64_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU9190609.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(26428..27774)
                     /gene="asnS"
                     /locus_tag="VWX64_001132"
     CDS             complement(26428..27774)
                     /gene="asnS"
                     /locus_tag="VWX64_001132"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU9190610.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     DMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(27790..28155)
                     /locus_tag="VWX64_001133"
     CDS             complement(27790..28155)
                     /locus_tag="VWX64_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9190611.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLTFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(28148..29335)
                     /locus_tag="VWX64_001134"
     CDS             complement(28148..29335)
                     /locus_tag="VWX64_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9190612.1"
                     /translation="MKLSNRVLEMEESVTLATGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSSSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(29332..29820)
                     /locus_tag="VWX64_001135"
     CDS             complement(29332..29820)
                     /locus_tag="VWX64_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU9190613.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            30141..30689
                     /locus_tag="VWX64_001136"
     CDS             30141..30689
                     /locus_tag="VWX64_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9190614.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(30967..31695)
                     /gene="yaaA"
                     /locus_tag="VWX64_001137"
     CDS             complement(30967..31695)
                     /gene="yaaA"
                     /locus_tag="VWX64_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU9190615.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(31774..31938)
                     /locus_tag="VWX64_001138"
     CDS             complement(31774..31938)
                     /locus_tag="VWX64_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU9190616.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
BASE COUNT         9261 a         7147 c         5920 g         9672 t
ORIGIN      
        1 gcttgatctc ttgaccgagt gcttgcgatt attttcataa gactgttgag catagtcggc
       61 agaataaacc tctttgaagc gcccttttcc aagacatttt cggactgtcc tacgcttgat
      121 tttagtgtgg atagtttgag gagcttttcc aagtagagag gcaatttctc tatttgattt
      181 tccttctttt ttccatcttt cgattaagct acggctatcg attgtcaaat gtttaccttt
      241 tgtagtataa ttgtcttgca tttctgtgcc tttcttgtgt ttgtggttga acaacaagta
      301 taacacagag gtgttttctt atgcctacaa gagctttcat tatttccatt ttcttttgga
      361 tttcactcta ttctgaaaaa cttgtgtata tttactgaag ctagcaagtc ttacctgtaa
      421 atttaatgaa agcaacacaa aatccgagag gggaatctcg gattaataga tagagagttt
      481 ttagtttaaa taaattgttt aaaatatcaa caacatcact tcttttctta acctgataag
      541 tcttgattcc taattttggg gctacgatta tattgtcctc aatatcgtct agaaagacac
      601 aatttctagg ttataactgg tatttatcga tagttactca tatacatcag tccacctcca
      661 tacttatgtg cgagcctctc tttgtattat acctccatac tcaccttaca gattcttttg
      721 gtaataatat ctttgcctaa tgtagagata gtcttgcaaa gaaaaaactt ccttgtagcc
      781 atgtttctga taaaagtccg gtgcctggaa ctggtaagta ttgacaaagg caaaacaaca
      841 atttcgattc ttagcttcac tttctgcctg ttgcaatagt tttgaaccga ttccttgtcc
      901 tcgcagttcc tcttttacaa acaaatactc gatttctagc caatttccaa aagtctctgc
      961 tatcaaacct gccaggagat tgcccttttc atcttcgaca taaagattaa gtggctcact
     1021 ttcagcctct tctctttttg aacggttata aacacgaatc agattcccta tttcttgcga
     1081 tttatgtgat tccttatttt ccaatctaaa gtatagtgaa atgaaataaa acatgcgcaa
     1141 atcgattaag gaatttaatc taatttctaa caatgtctta gaaatcaaag tgtactattt
     1201 taacttcaat gcactataca tctaatactc aataaaaatc aaagagcaaa ctaggaaact
     1261 agccgcaggt tgctcaaaac actgttttga ggttgtagat gaaactgacg aagtcagtaa
     1321 ccatacatac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag agtagcaaaa
     1381 tggaaaaagg agtgagtgaa gcacatcgcc tccccactcc tttttctgtt tttaggctgt
     1441 tttttcaacc ttcaagattt ttacatcata gctaccaaca ggcgtttcaa tggttgctgt
     1501 atcacctgtt ttcttgccaa tcaaggcctg cccaattggg ctttcatttg aaaccttacc
     1561 tgcaaaggca tccgcaccag ctgaacctac gataatataa acttcttctt cgtcctcacc
     1621 aatttcttgg atggtgactg ttttaccaat cgctacttcg tcctgggcaa ctgcgtcgct
     1681 attgacgatt tcagcatagc ggatttttgt ttctaagcta gagatttgtc cttcgacaaa
     1741 ggcttgttca tccttagctg cttcgtactc actgttttct gaaaggtcac cgtatgaacg
     1801 ggcaatctta atgcgttcta ccacttctgg tcgacgaacc aatttcaatt cttctaattc
     1861 tttttcaagt ttttcctttt cctcaagggt cataggatat gttttttctg ccatttttct
     1921 caactttctt ctgataatat tttctaaaga aaattatgtg aagtatcaca taattttagt
     1981 ttgtttagtt taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg tcttcttgat
     2041 tgttagcata gtagaccttg ccttctgtga catctgctac aaagtagagg ttatcgctct
     2101 tagtttgatt gatgcttgac tcaatcgcat ccagacttgg actatcgact ggaccaggca
     2161 tgagacctac atttttataa acattataag gtgaatcaat gttggtatca atcgcaacat
     2221 cctcagctag actgatattt tgccccagtt ttccttgggc atacaagatt gcaatattac
     2281 tttgaagtgg catatcacga ttcaaacgat tgtagaatac acctgcaatg agcttacgat
     2341 cttctgtctt ggcaccttct ttttcgacca aggaagcaat ggtcaacaac tcattgacag
     2401 tcaagttttt agatttgata gtactatagt aaggagatag gttcttatcc atagcagcta
     2461 acatctcatc aatcaagctc tcaatagttg tgctttcctt gatagagtat gtagctggga
     2521 aaaggtatcc ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa ctttccagta
     2581 aagtaggata tttcgctact gcttgactga taaacgtctc atcttgaact ttagccaaga
     2641 aagcctccgc tgtcaaagac tctttgaagt caccttgcaa ttgacccaca gtttgagcaa
     2701 tctgatccaa ggtataacct tctggaattg tcaaagtcgc aagtacaggt tcttgcggtt
     2761 catctgttcc acctttttgc aactctttga gtaagtcttc tgtactcata ctcttttgca
     2821 aattgtagta acctgctttc aagtcggtat aatttttata cttggcataa aaactaaaaa
     2881 tcagaccatg ctttatcaaa ccagcttttt caagcgtcgt accgatttct tgaacgtttg
     2941 aaccttctgg aattccaacc gtcacatatt tcttagaatt agcatcgata ggtaataagg
     3001 aatctagcac gtactggtaa ccaaagtaac cacctgctga gagcaaggca aggaatacaa
     3061 ggaatgaaat cacaaaagct ttcacatgtg acttcttctc tttcttaggc ttaacgggtt
     3121 ttgctccttc tctacggcta cgacgtgatg tatctctgat gatatccact gtttctgtag
     3181 caggcgtagg tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc gtataggaaa
     3241 cagctaccct tgttggggtt tcattgtatt ctctttcaag tttcttaggt ctaacaggac
     3301 ctggacctgg tcttgatcca ctttcttccg ctggagaaga aggtacatct tgacttggat
     3361 gacttggaac accaggagtt tctctttgaa tctcatctgc tggagaagct ggtacacctt
     3421 gacttgggtg agtaggcacg gtaggagctt ttctcataat ctcctctacc gttgacaagg
     3481 aatcagccat gagttcttca gctgaaggtt catttgcagg agtgcgaact actgcctcat
     3541 cttctttcag aacttcatca tagcctttta ctttttctaa atctctcaga atctgctctt
     3601 taaagcttaa tttctcttct tctcttgact tttcactcaa aagtttttcc tccttgttga
     3661 taatccataa tattatatct taaaagtcca aaaaaagcaa tctatgatac ttttcctaac
     3721 ttattttttc atttcccaga ccatatcata ccatgtttcc cctgcaaagg ttgactggga
     3781 ctggccttcg ttgacaaatc catgtttttc ataataggcg atgagatagt catgacaggt
     3841 tagattaatg ccatctctct catcttcaag agcaacttct ttcaaggctg tcagcaattt
     3901 ctgacccagt ccgagtccct gtgcctcctt ggcaatagac agacaggtca cagagatata
     3961 accaccaggc tcatgactat agtcttttat ttcttctgta aaagactggt cttgcagatg
     4021 gcggtgcagg ccaactggtc cttcgatata acccatgatt cttccttctt tttcagcaac
     4081 cagaaaagag gtctgaattt ctctcaaatg tgcttcaaag acagaaggag gaatggcttc
     4141 ttcgaccgaa aaattttcaa attcaagttc aacaatccga tccaaatctt ctaatcttgc
     4201 ttgtctgatt ttcattgttc ctccagataa aagggattaa accaaatcat actatagccc
     4261 tggctagtta catagagcaa agtttcttct tcatcaacaa aaccgttcat ttcaaaatag
     4321 gaaagcagct catcaggact ctccaaacga atccctttgt aatccagctc aactgccacc
     4381 tctttcaagg ctgcaagaag aagtgttccc aggccctgtc tctgatggtc agactcgatg
     4441 actaaagaat gtacttttag acattgcgga ttgtctgact ggggacttga taaaatatag
     4501 cctaaaagtt gattttcatc cctagctaga agaaaggtat ccgcacactt acggatactt
     4561 tcttctaaaa tatgggaaag ttgctgcttt tcagctggaa aagacgaggt ctgaagtgcc
     4621 cctatctcag gcaaatcaaa cttgcttgcc tgaatgatct taattggaat ttccatggga
     4681 acatcctatt gaacattgct tgtcaagtta gacaagagac gctcaaatga gtattcatag
     4741 gtttggatgt ctcctgctcc cataaagacg taaacagcat tgtcatggtc taggagtgga
     4801 gaaacatttt caacagtaat cacttggtgt tttttgttga ttttattggc taggtcttct
     4861 accttaacgt caccatgatc tacttcacga gccgagccat aaatttgcgc tagataaaca
     4921 gcatctgctt ggtttaaagc atgggcaaag tcgtccaaca gggcaatggt tcttgtaaag
     4981 gtatgcggtt gaaagactgc tacaatttcc ttgcttgggt atttctgacg agccgcatcc
     5041 aaggtcgcaa taatttctgt tggatgatgg gcaaagtcat caataatcac tgtatcattg
     5101 acaattttct cagtgaaacg acgtttaaca ccggcaaatg ttttcaagtg ctcacgcacc
     5161 aagttcaaat caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc attcatgata
     5221 ttgtgacgac caaaggttgg aatgtggaat tgccccaagt tttgtccacg gaaatgaacg
     5281 gtgaaggttg aaccagttgt tgaacgaaga agatcactag ctacaaagtc attgccttca
     5341 gcttcaaaac cataataata aattggtgca tcagacgtaa tcttacgcaa ttcagcatct
     5401 tcaccataga caaaaagacc cttggtaatt tgtttggcat agtcgttaaa ggcattgaaa
     5461 acatcctcga gacttgtgaa ataatctgga tggtcaaagt caatgttggt gataatagag
     5521 tattctgggt ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa gacaaaatat
     5581 ttggcattgg ccgaaccacg acctgtccca tctccaatca agaagctggt atctgtaatg
     5641 tgagacaaga catgagacaa catacctgtc gttgaagttt ttccatgtgc tcctgctact
     5701 cccatgctaa caaagtcacg cataaagcta cctagaaact catggtaacg tttgtagctg
     5761 ataccatttt ggtccgcata ggcaatttcg acgttgttat ctggacgaaa ggcatttcca
     5821 gcgataattt ccatatcacc gtctagattc ttttcatcaa aaggaagaat ggtaattcct
     5881 gcctgctcaa gaccgcgttg ggtaaagtag tacttttcaa catctgatcc ctgaaccttg
     5941 tgccccatct ggtgcaacat caaggccaag gcactcatcc ctgatccctt aattccgata
     6001 aaatgatatg tctttgacat gttttctccc ctattctgtc attctggtca gattcaactc
     6061 ttgggcaacc cgacgttctt gttctgtttg tttacttttt ttattgtaga tttggctctt
     6121 ctttagaaaa tcataattgt ttttctttgg agcaggtgct gacacttctt cattcttggt
     6181 agggatagaa tgaacttctt ccgccaagat ataatgagac tgggtcaatt tttggctata
     6241 tttgacaaat tcaccaggat tttccttttg gaaaggagtt gtcggttgat tgccctgtct
     6301 aactagactg ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta ggtagttagc
     6361 agagcgtttc tttttcaagt ccgcacgcgc ttcttcacgc gccacctccg catagctctt
     6421 tccttctttt ttaaccccta aaggagcctt tttaggtttt tcgacttgct tttcaatcgg
     6481 ttttactggt ttttcttcag caataggagc ccattctaaa taatttttat ctcgatactc
     6541 acccttgata ttactgatca gatcagactc atcatagaga ttcatgactg gcatttcagt
     6601 caacatgacc tcgtcatctg acaccaatgg aaatcgttct tgtttcattt tctatttcct
     6661 ttcaacactt cattatagcg tattgtcttg atttttcaag tgctggcttc agaaattccc
     6721 aaaatttctc taatttctgc tagggtcaga ctaccacgtg actctgtgcc gtccaatact
     6781 tgtgacacca gatgtttctt ttgttcttgg agttcctgaa ttttttcttc aatggttccc
     6841 ttggtcacca agcgatagac ctcaaccgtt tcttcctgac ccatccgatg ggcacggcca
     6901 atggcttgcg cttccaccgc aggattccac caaaggtcaa ccaagatcac tgtatctgca
     6961 cctgtcaggt tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc atctctttct
     7021 ccttggttaa aggccttggt catgtcttgt ctttccttgg ctggggttga acccgtaatt
     7081 ttaaaggaag tcaggcccaa gtctggcagt tcttgttcaa ttttttccaa cattcccttg
     7141 aactgagaga aaatcaagac acggtgtccg ccgtctgcca cctgtaccag taggtctcgg
     7201 agactatcta gtttgccgct ggctccctga taatcttcca taaacagggc aggagtgtca
     7261 catatttgac gcaagcgcat caaaccagat aaaatttcca cacgacttcg ctgaaattcc
     7321 tgttctgaca cttgagccag atggtctcgc atctgttgta actgggcaag gtaaatagcc
     7381 ttttgctggt cttccagttc atttttataa accacctcaa tcaagtctgg caattcagtc
     7441 agaacttctt ctttcttgcg tcgcatcacg aaaggcttga taaactgagc cactcgctct
     7501 gctggcaatt tcataaattc tttcttgctt ggcaaaagtc cgggcatgac gatttggaaa
     7561 atagaccaca actcacccag atggttttca atcggagttc ctgacaaggc aaagaccgac
     7621 ggcaccacaa attgtctcaa ggtctgggca atcttggtct gggcattttt catgacctga
     7681 gcttcatcta agaaaaggaa gtcaaaggcc atcccctgat aaagctcact gtcctgacgg
     7741 aaggtggcat agctagtcac atagatttga tggctatcgg caagaatctc ctcacgactt
     7801 gctttcaaac catgaacaac agccacatcc aactgtgggg caaatttctg aaactcatcc
     7861 gcccagttgt aaatcaaacc cgacggagcg agaatcaaga ctcgactttc ttttgtcact
     7921 tgactagtca aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc atcagccaaa
     7981 atcccaccaa aaccataatg atggagcatc tgcaaccagc caattccctt ttcctgataa
     8041 tctcgcaagt cagccttgac ctgagttgct tgcaaaggaa agtcctctgg atgcgtcaaa
     8101 tcctgggcca gattctggaa ttcttgtgaa aaagaaacac ggtctcggtc tcgcccttca
     8161 aagagatgag ctaaactgta ggccaaggat ttccgagcct gcaaggtccc atcttttaat
     8221 tcaaattgcc ccagtttctg taaattttgg cgaattttct tggtttcttc atcgaaaaag
     8281 taaacttgat tagacgaatc aatataaaaa tcctgattgg caaccaaggc ctgcatggct
     8341 tggtcgattt cctcctgggc aatatcttga aaatcaaact ggatttccaa gagacctccc
     8401 ttggaggcaa tctgcacctg aggactcgct aggctataaa gctcttctag tttatctgat
     8461 aggtcaacat gcccgagttt ttcaaagact ggaatgatat catgaaaaaa atgatagaca
     8521 gactctgctt ttaaggcctg acgccaagat tgaaaatcgg cttcaaagcc cgcagccaaa
     8581 cagacttgga aaattctttc ttctaagtcc acgtcacttg aaaatggtaa ttcttctagc
     8641 tcttgtcggc tagatacctg tctatttcca taatcaaact gaatttctaa acgaatccga
     8701 ttatcttctt ccctgtcaaa gtaaaaagag ggcgcaaaag ttttgatttg tagacgttct
     8761 ggagctgaaa cggtgcccat ctggataaaa agagtcagac aggaggccaa tttgtctcga
     8821 tcactgctat caaattgcag gtatttcttt ccttgttgac ccacaggtaa cactttaatt
     8881 tccttgagaa gacgcatctg ctggtctgtt aaaaaataaa cctgaccttt atggaaaagt
     8941 actgctccct gataaaagac attgacccta ggactctcac tgatttccat ttcaaaatag
     9001 tccaagtatt ctgttactgt aaaggcaaat agattggtat cagcatgcat atcctgaaaa
     9061 agcagggttt ggtagctatc cacttgatgg tcaaattgaa aatggggcaa ggccatcagt
     9121 aaattcacac cctgctcaaa aaaggtcaga gggaaaaaga ggtgccgacc ttggttttgg
     9181 aaaaagaggt ctggaaccag cccttcctcc gttagtccgt gcaagaaagt caaaagttct
     9241 tggctggcat catcaaaggc ttcccaagaa agagactcct cataaatctt gccaatcata
     9301 tacgactttc tctgctcgac aatccttaaa aaaagtggaa tatcccgaat gacatagtat
     9361 ttttgtctat tgatttggcc gattctcaga gtccacaaga tatgattggt tcctgcttcc
     9421 acctgaccca cagctgataa ctcataggcg cattctgatt tcggagataa aattcgattc
     9481 aaaaacttgc cacccaaggt caccttggtt tcaacggcct ctttttcttc atgaccttct
     9541 tccagactcc acaagatttc ctgaccacgc tcatcatttt tcagaaaatg ctctagcgct
     9601 gccaaatgca cacagtagcc cctcttttga aaagaatcac aggcacaaaa aaccaaatca
     9661 tcctctaaac tatagcgcag ttcttcttct gcaacgcgag cgtagagccg attgttcttt
     9721 tccttgatga tatcaacctt accagtttca taaagggcaa caccttcgat acgaactttc
     9781 cccggaatca atttagccat attttcacct ttaccttatc tgtttattat accatatttt
     9841 cgcctatgaa aatagccttc taggaagact tttctcctag aaggctggat ttttaacgtt
     9901 tggcaaaagt agccacaatc cgctgacaga cttcttgcaa cagagatttg ggcatagcta
     9961 tattgatgcg ggaatggaga cttccttcct ctccaaaatc caaaccacgg ttgaggataa
    10021 ccttggcttc atttctcaac aactcttgca atgtttcatc agtcaggtca taggctgaaa
    10081 agtcaagcca aatcaagtag gtaccttgcg gtttcatgac cttgatttta gtctcttttc
    10141 caaatagatc caccacataa ttgatgtggt cttcaaagac ttgcttgagt tcctctagcc
    10201 aatctttacc gtatctatag gcagcttctg tcgccaaata acccaagcct gaaatttcat
    10261 gctgattatt ggccaacagg cgtttctgga aagctagtct caacttagga ttttcaatga
    10321 ctgcatagga attttttgtt ccagcaatat taaatgtttt agtggcactg ctcaagacga
    10381 tagcaaaatt tttgaaggca ggattgatgg tattgaaaga ctggtgtttg tgaccaaaga
    10441 gggtcaaatc ttggtgaatc tcatccgaaa ctaacaaaac accgtgtttt tggcagagtt
    10501 ggccaatctt ctccaacact tctttttccc aaacacgtcc accaggattg tgagggttgc
    10561 aaagaatata gagtttaacc tcctcttcca ccaaatcctt ttcaagttgg tcaaagtcaa
    10621 tctcaaacag accatccttt tccactaagg aattagtaat caatctacga ttattcaact
    10681 tgacactgcg agcaaagggt gggtagacag gcgtgttaat taaaaccgcc tcgccttctt
    10741 ttgtaaaggt ttgaatagct gttgagatgg ctggtaccac accctcgata aagacaagag
    10801 cctctttgtc aaagttgtaa ccgtattgtg tagcttccca cttttgaact tccttaatta
    10861 agtcttcact ggcataggta taaccataaa ccagttggtc tgcgtaagtt tgcacggctt
    10921 ggcggatttc aggcaagacc acaaagtcca tatccgctat ccaagctggt agaacttcac
    10981 tatccgtttc tgtttctttc catttatagg tatggtgccc taaacggttg ggcaggcttg
    11041 taaaatcata ttttcccatc tttgtcttat ccttctaagg cttggcgcaa atctgcaatc
    11101 aaatctctag catcctcaat cccaatagac aaacgcaaga ggtcatctgt caaaccataa
    11161 gaatggcgta cttctgctgg aatatcagca tgagtttgag tcgttggata agtaataaga
    11221 ctttccactc cgcccaaact ttccgcaaaa gagaagacct tgagactgtt caaaatatga
    11281 ggaatgcgtg tttcatcggc tactttaaag gaaatcatgc ctccacgacc agtgtagaga
    11341 acttccttaa ctgctggaga atccttcaaa aaggcaacca cttcttgggc gttagctgtt
    11401 gagcgctcca tacgaagaga caaggtcttg agaccacgaa gcaactggta gctgtcaaat
    11461 ggagacaaga ctgcccctgt tgtattgaga ttgtaaaaaa gcttctcgta tagttctaaa
    11521 ctattggtca caaccactcc agccaagaca tcattgtggc ctgctagata cttggttgct
    11581 gaatggagaa cgatatctgc tctatcttca atcggacgtt ggtagatagg gctatagaag
    11641 gtattgtcca ccaccacttt ggcaccctta gcatgagcca attttgctag tttttcgata
    11701 tcaaattcca acatcaaggg attggttggg gtttcgatat agagaacatc cacatccttt
    11761 tctaactcgg caatcaactc ttcttctgta ttggcatagg taaaatggaa acgaccttcc
    11821 tgctccactt ggttaaacca gcgaaaagaa ccaccgtaaa gatcacgcac tgccaagacc
    11881 ttacttccta ctggaaagac gctaaaggcc agtacaatag ctgacatccc tgagctagtc
    11941 gctaaggcat agtctgctga ctcaatagcc gccaagactt cctcagcctt actacgagtt
    12001 ggatttttag tgcgcgtata gtcaaaccca gtagatcgac caaactctgg atgctgatag
    12061 gtcgttgaaa aatgaagcgg tgtcaccaat gcacctgtcg cttcatctga cttaataccc
    12121 gcctgggcca aaattgtgtt aatgtgtaat tccttgctca tacaatacct ccaaatctat
    12181 agtaactatt gtaccactta ttttcatcaa ctcattttct tcttttcaag agctagttat
    12241 agtttcaaac tatataaaaa gggagttttt cctgctccct ttaatagact ataaaatggt
    12301 gaatctcaaa agacacttca ctctatcatt tgctcctgca caaaacgagc ataacgctca
    12361 tgattttcca gtagttcctt atgagttcct gagccagtga ttttcccctc ctctaagaag
    12421 aaaatacaat ccacatcttt taccgttgac aaactatgcg ctataatcac aaccgtcttc
    12481 tcctttaata cagaatagag gctactgata atcgcatact cagaatccgc atcaagatta
    12541 gcagtggctt catcaaatat aagaatttca gcatctttta agtaggttct agctatttga
    12601 agtctttggc tttgcccccc tgacaagaat cgtccgcgtt caccaacttc agtatctagt
    12661 ccctctttca tggagcgaat ctcatcacct agtgatacta agtctagcac tttcatcaat
    12721 tcatcatcag ttactaagcg attcaaaccg agacaaagat tgtcacgaat actgccagat
    12781 aagactgcat tattttgtga aacccaagcg attttacttc tccattcttt taagttaaaa
    12841 tcatatatac ttgattgctc cattagaata tctcctgaaa gcggtttata aaaccgctct
    12901 aacaaacgca caatcgttga ttttcctgat ccagatggtc caacaaaagc aattttttgc
    12961 cccttgaaaa ttgaacaagt aatatccttt aagacaggtc gattttcatc ataaccaaaa
    13021 tagacatggt taaaattcaa cccttgtcct gataccgatt ttcctcactc aaatttttct
    13081 ttaggaactg caagcaagtt ctccagtgca acttaagatc ccttgctcct agaataaaca
    13141 gttacaaaat tagctatatt actaatagga ttaagtaatt gaaagaggta aatcaaaaac
    13201 gaaaccaagg ttcccacaga tatatatcct gcgctgaccc gataactccc ataggttagc
    13261 atcacagcta tagtcgcaaa gataaataag agagcaaacg gggtctcaaa agaagtaacc
    13321 ctatctgatt tcagtgaatt gttttgtacc ctttcaatac aattatccaa aacattctgt
    13381 acacttttct ctgcttggtt agtcttaatt aattcatgtt cttgaatctt ttcagtcaat
    13441 tgccctgtta aaaatccgat ttccttctgt aaacgacgac tatacttttc actgatattg
    13501 gaaaggggca agataataaa catcatacaa ggaagagtga tgaataaaag tagagaaaga
    13561 ttccaatcaa gactaaataa gactacaatg gaaccaagta ccataactaa actcagaata
    13621 atatttggga aagtcgtaat taaaaactca cgaatgacac tcatgtcatt gacaatggca
    13681 gaagtcaact ccccactttg gctcttatca aagaaggatt tctctgcata aatcaacccc
    13741 tatatcactt ttttcctgat ttttgctatc tttttttcac ccgattgact aaacagatag
    13801 taaccaatag aagaaaacaa ggcttgacca ataaaaatca aaaacgattg aaatactttg
    13861 gaacctatat tttcaataga actcccatct attaaacctt ttaagataag gggaagcaac
    13921 aaagcaagta gactagacag aacaaggaag aaactcccca taatcacctt agtatctact
    13981 cttaataatt ttaatttcat aaatactcct tataatattt caacggataa agtcaggaat
    14041 aactcaattt gaggataaaa tctaataaat cttcctataa caaaacgcat aacatctagg
    14101 attttatata cctgatatta tgcgttttta agcacaaaga cttcttacac aaacttatct
    14161 acaattagat tttatttgac atgttttgcc aattcttctt gggctttttt attggattct
    14221 tctttttctt tcaaccattt ttctctggct tttgcatatt cgtctgttgt gacaatctta
    14281 tcttgtactt tgaggtattt atatgattca accccttttg taccggttaa accataggca
    14341 gcagcaaatg gtacggttct tctcaatgat ggtgttcccc cacgcgaaac acttggaaga
    14401 actaaagaac tatcaatcaa ccaagcttga atatcagcat atttctcata acgtttggct
    14461 ggatcttgct ctttattagc ttcttccaac atttgagtat agacatccag cccaacttcc
    14521 ttagccttgt cattggcttc tccaggctct agtccaagat tttgtagaac tcctccacta
    14581 ttagtattaa aaatatcgag ataggttgac gggtcttgat aatcaggtcc ccaaccgcca
    14641 tgatataaat catagtcttt ctgagcagct gtttgagcaa agtagcctga actgtcaaac
    14701 tcatctgatg ttaattgctg aatgtcaatc actacattat cagaacctaa aacagattca
    14761 attgattgtt tgatagaact aactccttgt atgcctactt tatctgttac ttccacagtc
    14821 ttatccaagt ggattgggaa ttgaacaccc tttgcttcga gttctttctt agcttccgca
    14881 aacttagcct tggctttctc aggattgtag taagggtctt gaccatccgc aaagttgata
    14941 ccttgccatt ccttaccata gttgaccatc ttagaggcta caacttcacc aaagtctttt
    15001 cccttgatac tgacaaagtt tggaggaacc actaggttac gcaaaatctt tgttgcacct
    15061 tctttccctt cagactgagc cccataagat gttctgtcaa aagcaaaatt gatagcctga
    15121 cggaagtttt tattgagaac tgcttcctga gtcgatttct tttcaatgtc acttgtttta
    15181 gaagtataat tgtaagactt cctatctagg ttaaaattaa agaaatatga agttgaattt
    15241 tgcatactat agatgatatt gtttttgtat ttttctttaa tcccttcata gctggagctg
    15301 ttaggaaaaa gacgagccgt agtataagca ccagctgtaa aattacgttc cagtgattct
    15361 tgatcgctac catcatagta ggtcaatttc acatcgtcta caaagacatt cttagcatcc
    15421 cagtaattag ggtttttctt atattcaata gcagattttg agacaagtgc tttcatcaag
    15481 aaaggtccat tgtacaaaat actagatgga tccgccttcc caaaatcatc cccttttgat
    15541 ttcaggaaat ctgcattaac aggaaaaagt atcgttgcaa gtgtttttga attccagtaa
    15601 agttctggtt taaccaaagt atattgaacc gtttggtcat caagtgcctt gacaccgaca
    15661 gttgaaaagt cgcttgtttt accagtgata tagtcatcca aaccagcaac agagtcctgc
    15721 actagataca aggcttctga ttttttatca actgcatatt gcaaacctgt cacaaaatcc
    15781 tgggcagtta caggcgcata ttcttctccc tcagaagtaa accacttggc atccttacga
    15841 agtttgtagg tataggtcaa accgtcctga gaaacagtcc aatcctctgc taatgatgga
    15901 ataatattcc catattggtc attttctaat aacccgtcta ccaaatttgc aacaatatcg
    15961 gatgttgctg cgcggttttc tgctagatag ttcaagctag atggatcact tgaataaaca
    16021 tagttgtagg tttttgacgc cgtgctagaa tttccacacg cgctcaataa aactcctgta
    16081 cccaggacaa gacctgccaa ggttagatat ttgctcttag actttttcat ttccagaacc
    16141 tcctgcttta aatatttgtt ttattataca acgtttggtt tgtttagtca attgtttttc
    16201 caaaaaatcg aaaaaaacct cattttctat ttttgaaaga taattttagc tatttttacg
    16261 ctaaaaaagg aataagtttc aagttctcct aaaagattgt tcaacttatt ccttttattt
    16321 ataaatgcta ccttacgaaa gcttaaattt tgctcgcagg cgatctgctt gggcttttcc
    16381 tattacctta tctaataaat aggtacgcag actcataacc atataaagtc caccccccat
    16441 ggcaccgaca agagctacat aaaagaagct ccacaaacgt ccacttggtt ggaagaaaaa
    16501 tcctaacagc cactggatgg ttcctattaa cagaaacatg actagggtca gcaaactgat
    16561 taaaatggtt cgcttcaaaa tcaccttgcg cttgacacca gttactttac aaatatcccg
    16621 atacatcaag acgttaggaa tgatgagagc aatggttgtt gaaatcaaag gaccataact
    16681 gtggaagagg gcgatggtag gtagttgcaa gactagcttg gcaatagaac catagataaa
    16741 atagagaacg gccttgcggt tgcggaacat ggcctgaagc attggagaca agaccatgta
    16801 caagcctaaa ataatagact gcaaaactgc aaagacaaat aagcccagag ccaaactatc
    16861 tggcttacca tagaagaccg tataaagagg ttctcctacc ataaccactc caaccgttgc
    16921 tggtagcaag aacataaaga gtagggtgag actgtcctga acgagacgag aagctgcttt
    16981 caagtccccc ttgacatagt tttccgtcaa aagtggcaaa ccaacactcc caatcgaaac
    17041 ccctacagaa atcaaaatca tcgtgatttt attaggattg gctgagaaat aagaaaacat
    17101 gacaaccaag tcctcattgc tgtagttggt aaaccagctc atactattga taaaggtcag
    17161 ctgatccaaa atctggaaga gctggatggc agaccctgtc aggataaaag gaatggcttc
    17221 cttagtggta tcaaccaaga gacgcttact gttaatctta tctcctgttt caaagactct
    17281 tttgagtgaa ccttcttggg caaggaaata aatcaagact gcaaaactgg ctaccatacc
    17341 gacaaaggca gcaaaggttg attgggtaac ggctgctaga taatctcctg aaccgagctt
    17401 cataatgata aaggttgcta ggagcatcca gataacacga atgacctgct cagcaatttg
    17461 gctcatggca tagggtttga ggttattcat cccttggaaa aatcctcgga taacactcat
    17521 agacgggaaa atcaagactc cccaagccaa gctttgcatg attgggatca agtctttgcc
    17581 cacgccagac aagtctgcta gccaaggagc aaagacatac aagactaaag caaaaaccag
    17641 gcctagtcct gtcataaagc ctaagaagct ccgaatcagg gcaaagctat gctcttcttc
    17701 tcgcatggta ttatacttgg caacttgctt ggccaccgca actggaatcc ccgctgttga
    17761 aaccaacaag aaccaagcat agatattgta acccatggta aagagaccat ttgccttagc
    17821 tgcataagcc cccatccaga tgtaccaagg gataatataa acagccccga gtaggcgact
    17881 gataaagtta ctagccgtta gccaagcagt cccccgtaac atctgggcct gctggtgatt
    17941 gttttcgtgc gacatagatt cctcattcaa ttttgatagc taggaaaaac tccttatctt
    18001 ccattataaa cttttccttg ttacttgtaa atttacgact ttcggtttac aatagaaagt
    18061 atgattaaga ttgaaaccgt attagatatt ttaaagaaag atggcctttt tcgagaaatt
    18121 attgaccaag gtcattacca ctacaactac agcaaagtta tttttgatag catcagctac
    18181 gacagccgaa aagtaacaga agacactctt tttttcgcaa aaggcgctgc ctttaaaaaa
    18241 gaataccttc tttctgctat aacacaagga ttagcttggt atgtagctga aaaggactac
    18301 gaagtcggta tccctgtcat cattgtgaac gatataaaga aagccatgag tttgattgcc
    18361 atggagttct atggtaatcc acaggaaaaa ctcaaactcc ttgcctttac tggtactaag
    18421 ggtaagacaa cagcagccta tttcgcctat aacatcttat ctcaagggca tagacctgct
    18481 atgttgtcga ccatgaacac aactcttgat ggcgagactt tctttaagtc agcgttgaca
    18541 acccctgaga gtattgacct ctttgacatg atgaatcagg ctgtgcaaaa tgaccgtacc
    18601 cacctcatca tggaagtctc cagtcaagcc tatctggtca aacgtgtcta tggtctaacc
    18661 tttgatgtgg gagttttcct aaatatcagc ccagaccata tcggcccgat tgaacaccct
    18721 agctttgaag actatttcta ccacaagcgt ctcttgatgg aaaatagccg agcagtcatc
    18781 attaacagtg acatggacca cttctcagtc ttgaaagaac aggttgaaga tcaagaccat
    18841 gatttctatg gtagccaatt tgataaccaa atcgagaatt ccaaagcctt tagcttttca
    18901 gctacgggta aactcgctgg agattatgat atccaactca ttggcaactt caaccaagaa
    18961 aatgcagttg ctgctggact tgcttgtctc tgtctcggag caagtcttga ggacatcaaa
    19021 aaaggcatcg ctgcaacccg cgttcctggt cgtatggaag tcctcactca gaaaaatgga
    19081 gccaaggtct tcatcgacta tgcccacaat ggggatagtc tgaaaaaact catcaatgtg
    19141 gttgaaactc atcaaaccgg aaagattgct ctggttctgg gatcaacagg aaacaaggga
    19201 gaaagtcgtc gtaaggactt tggcctcctc ctcaatcaac accctgagat tcaagtcttt
    19261 ctgactgctg atgaccctaa ctatgaagac ccaatggcca ttgcagatga aattagtagc
    19321 tacatcaatc atcctgttga aaagattgcg gatcgccaag aagccatcaa ggcggcaatg
    19381 gctatcacaa atcacgaatt agatgcagtt attattgcgg gtaagggagc cgattgttac
    19441 caaatcatcc agggcaagaa agaatcctac ccaggagata cagccgtcgc agaaaattat
    19501 ttataagaat agaaaaaatc aagggaaaat gaaacccttg attttttcct attatttagt
    19561 aaaaacgttt ttcaaacctt caacggcacc ttctacagca ccttttgcgt cttctacaac
    19621 gtcttttgcc ttagcaactg ttttttcaac agctccttca agttctgtct tgctgtctcc
    19681 agtaacttta ccaaaacctt ctttgacagc gcctgttgct tgttccaatt tgttttcaag
    19741 tgacatatga ttgtctcctt tagtttattc cgatatgtgt taccggttac atatagttta
    19801 taccgaatac taaggaaagt caaacaatgt gctcagaaac aagaaatcac gctaagtaga
    19861 aagttaatct ctccttatca aaatcgatag ccaactcata ctttctatct tcattttgca
    19921 caatatagcc taagacaacc aaactgtcca caaagatatc acgacatttc tgcataaggt
    19981 ggtctttttt gagaaatttc aacaaaaaag ccgtcatata cttgagtgca tactcaggat
    20041 taacatctcc taaaatgtca tagagctcct gctgtttttc tgtcaaagga tactgctgtt
    20101 tgaccttgta aaaataattg gacagggtca ttttaatgcg cgcaaagtcc gtcttttcaa
    20161 ctaaaatagc tgcattgatt tgattgcgca attccgtctc aaaactctgc tccaacaagg
    20221 cttgatagac cggactagct tctctgacaa aaatctcttg atccagttca agactatcaa
    20281 gtgattcaag cgtaggaaaa ttgaggtaat agcgcttatt ttcacgtaga atcaagcctg
    20341 cctttatata ctcttccatg agtttatcaa ctgcaacatc tggaaattga gccttaattt
    20401 cccgtagaat cacatcctca tactggtcca gatagcggat caattctcca aaaatggctg
    20461 tctcgtcaaa cgagatggat taaaaatctg aatcatgaag attcctttct ttacattgta
    20521 acagaggcga tgctgccaac tgactaggat tggtaccagc ttggttcaga ggaacaggca
    20581 gacctagttc tatgtaatac tccctccaaa aatcactaat ctcctgctcc ccatctccaa
    20641 atttcatagg aatagtttca aaaataggta ggatttctgc tatatactgg gagcagtaga
    20701 aaccagctgc atctggatag aaagaagcat tgtagggtgc tccaagatgt ttgcaagctc
    20761 tttccttcac cgactggata tccatttctg ggtaaacata gaggtcgtat aaatgattgg
    20821 actcaaagaa gtctgccggt tcttgacaga caacaccagc ctgtccacta gcatgataaa
    20881 tcatcccatc caaataaatg gcaacatggc tatagttacc tgtggaagtc tggatggcct
    20941 gtcccatgtc tgacccatct ctcacaaaaa tcaaatcgcc attttctaac atacttcact
    21001 cctagaaaaa aggagccgaa actcctttcg atataaggca aactagactt tccgattttg
    21061 agctgacacc caaaatctta cgcattaaag ctttcagtca attgaggtac cacttgtttc
    21121 ttacgtgaaa cggcaccagc aaggaaggca tgattgtttt caagtttgaa gttgaaagcc
    21181 gcttcgacct tgtccatatt ggcaccaaga gccaagattt ctgagtttga gttgacgata
    21241 tctgtaatca tcaagacaaa gtcagagtag ccgtttgatt cgttggcagc ttgcattgca
    21301 gcttcaattt ctgcttggcg ttccaaaact tcagcgatgt caactgtgtt cacttgggca
    21361 acacggacat tatttccgtt gagttcaaaa gtcttagcat cgatgtcaat caattcttca
    21421 gcagatttgc tagccaagtt ggtaccagct ttcaacattg ccaaaccata ttcttccaag
    21481 ttcacaccag ccaattcagc caattcagga gcaatgattt tatctgttgg gtgtgttgtt
    21541 ggtgatttca aaagaagggt atctgaaatc aaacctgaaa gcatcaaacc tgcaatctct
    21601 ttaggcacag ctacaccatg ttctttgaac atacggtaaa cgattgaaga cgctgatcca
    21661 actggctcca aacgcatgta aagtgggctt gcagtttcaa agttagccac acggtggtgg
    21721 tctacaacac cgtaaacttc tacttcagcg atatctgata cagattgttg gaattcattg
    21781 tggtcagtca agataacttg ctctgccccc tctgctttgg cagaagtgat aacacgtggt
    21841 gcttccacac caaaatagtt caagacaaag gctgtttctt catttggagt tccaagggca
    21901 acagcttccg tatccaaacc gtaagcttct tttgcaaggt aggcaaaagc tacagatgat
    21961 ccgatggcat ctgagtctgg attttggtga ccaaatacta gaatcttgga catgataata
    22021 cctcattttg tttattttct ttattgtagc atttttttcg ctttttgaca aaggtaagag
    22081 gagtcaaagg actccccacg attcttcaaa ataactgagt aaatttctat cttgattttc
    22141 agataaaaat tcttccttct gtggcctctt cttacgcttg agaagagctt cagccgacat
    22201 ggcttcttcc ttactggcaa aaccttgagc atagataagt ttgactggca agcgtgctcg
    22261 tgtatatttg gctcccttcc cactattgtg gatagcgagg cgtcttctca tatcagtcgt
    22321 atagcctata tagtaggatc catcacgaca ctccagaacg tacatataag ccttatgatc
    22381 cataataaat ctcttcgatt tcgggcgtat aagagccatc atcattgtgg acaatcaaag
    22441 gaggtaagac cttaaagcca cttgttgagc catccttgat cgcctcaatc aaaagcatat
    22501 tggcttcctt ttctcttttt ggataaacaa actgcaggcg cttaggggct agattatgtc
    22561 gttttaacgt atccaaaata tccagaagtc gatcaggacg atgaaccatg gccaaacgcc
    22621 cattagactt gagaatactc tgggcactat gacagatttc ttccaaatta gtcgtgattt
    22681 cgtgtcgagc caagagataa tgttcactct cgttcagatt agaataagga tccaccttga
    22741 aatagggtgg attacacaaa atcatatcca ccttactccc ctgaatgtga gcaggcatat
    22801 ttttcaaatc atcgcagatg acctgcattt gctcctctaa tccattcaaa cggacagagc
    22861 gttcagccat atccgccaaa cgctcctgaa tctcaacaga caatatctgt gcttgagtac
    22921 gagtgctagc aaaaagcccc actgctccat tcccagcaca gaaatccaca atcaacccct
    22981 tcttaggaaa acgtggaaat cgtgataaga gaacactatc caccgaatag ctaaaaacct
    23041 ctctattttg aatgattttg atatctgtcg aaaagagctg gttaatgcgc tctcctgatt
    23101 ttaataattg ttcttcttcc atggtcctat tatagcaaat ttatattaac attacaaaaa
    23161 atataaaact ctaaactact tcttcttttt taaatggtgc agggcttctc cagtccagat
    23221 tggtagcatt cgtcgaaagg gagcaaaacc gtagttaaag cggtcgcttg aaaagcgtct
    23281 ccgtctagga aactggtact tttcttcctc caaagtgcgg atagaaagac tggctttccc
    23341 cgtaaattca tctaaatcca ctacctgaac ttgaacctct tcatcgactt tcaaggtttc
    23401 atgaatattt tcaataaatc ctgtccgaat ttctgaaatg tgaatcagcc ccgtatcacc
    23461 cgtctctaac tcaacaaagg caccgtaggg ctgaatccct gtaatacgcc cctttagctt
    23521 atcaccgatt ttcaccttag tcctcgattt caatagtttc aattacaaca tcttcaactg
    23581 gcttgtccat agctcctgtc tcaacagcag caatgacatc caagacagcg taagatgctt
    23641 catcagctaa ctgaccaaaa accgtgtgac ggcggtctag gtgaggtgtc ccaccttgat
    23701 tggcatagat ttctgcaatc ggttctggcc aaccaccacg agtaatttct ttcttagaat
    23761 aaggtaggtg ttggttttgc acgataaaga actggctgcc gttggtattt ggaccagcat
    23821 ttgccatgga aagagcacca cggatattgt aaagctcttc tgagaattca tcctcaaaag
    23881 attcgccgta gattgactcg ccacccatac cagttccagt tgggtctcca ccttggatca
    23941 taaagtcctt gataatacgg tggaaaatga caccatcata gtagccatct tttgaaagag
    24001 atacaaagtt agccactgtt ttaggagcat gttcagggaa aagcttgata cgtaagtctc
    24061 cgtgattggt cttaatagtc gcaagaggac cttctactgt ttcaatgtct acttgtggaa
    24121 aatgcaattc tttttctacc ataccaaata cttctaaggc atcaaaaatg ccatcttctt
    24181 ctaatgtttt tgtaatataa tctgcttttt ctttgatttt atcatgagaa attcccatgg
    24241 caacgctgat tccagcataa tcaaagagtt ccaagtcatt gagaccatct ccaaaaacca
    24301 tgaccttctc tggtttcaag ccaaggtgtt ccacaacctt ttccaccccc gtcgctttgg
    24361 agcctgaaat cggcacaata tcagacgaat gttgatgcca acgaaccatg cgaagtttgt
    24421 ctgagagact gtcaggcaag tgcaagtcat ctcccttatc ttcaaaagtc cacatctgat
    24481 agatatcttc tttttcatgg aaatcgggat ctacatctaa gtcgggataa attggattga
    24541 tagcttcact catcatatcg gtgcgagtcg acaacttggc atcatgactc ccaaccaagc
    24601 catactcaat tccttcttgc ttagcccaag agatatactc ctcaacatat gacttttcaa
    24661 tctgatgctg ataaatgacc tgaccttttt tatcttcgat ataagcccca ttcaaagtta
    24721 caaaaaagtc aggcttgaga tcacgaatct ctggaacaac accaaaaatg ccacgtccag
    24781 aggcgattcc tgttaaaatt cctttttcac gcaactgttt aaaaacagtg ggaattgtag
    24841 ttggaataaa ccctgtcttt gaattccgca atgtatcatc aatatcaaaa aagacaatct
    24901 tgatcttctt tgccttgtat cttaatttcg cgtccatctc actacctctt tcaatctaac
    24961 tctttccatt atatcataaa gtaggcaaat cccctatttt caaaaagttt atcattttta
    25021 ttttaatttc ttggatgaga aaaaagacat atttatgaaa aagctccatc gtgcttttaa
    25081 tgtgttctct tgttttcaaa ctcgtaaaaa gggagccact gagcctaact cgctctctca
    25141 tttcaaagct tgtgaaaaaa gacccgttgg ggtcttaatt cgctttcttg ttttcaagct
    25201 catgaaaaag agacccaacc gggtcttttc tttaatcttc gtttacgaaa ggcatcaaag
    25261 ccattacgcg agcgcgtttg atagctgttg ttactttacg ttggttttta gctgaagttc
    25321 ctgttacacg acgaggaagg attttcccac gttctgaaac gaaacggcta agaagctcag
    25381 tatctttgta atcaacatat tcaattttgt ttgctgcgat gtaatcaact tttttacggc
    25441 gtttgaatcc gccacgatgt tgttgagcca tgttttttct cctttataag tttagttgtc
    25501 cattagaatg gtaaatcatc atctgaaata tccaatgggt ttgttgctcc aaatggattt
    25561 tcattacgtg aaaagtctgg tactgaattt gtaggtgctg aatagtttgc agttggtgca
    25621 gagtaagctc cacctgtgtg accctcacgc acactacggc tttccaacat ttggaaattc
    25681 tcagccacga cctctgtcac gtagacacgt tgtccttgct ggttatcgta actacgagtc
    25741 tggatacgac ctgtcacccc gataagtgag ccttttttag cccagttagc aagattttca
    25801 gcctgttggc gccacataac gacattaata aaatcagcct cacgttcacc attttgactc
    25861 ttaaatgtac ggtttactgc aagagtaaaa gtcgcaactg ctacatttga tggggtataa
    25921 cgcaactcag cgtcacgtgt catacgccct acaagtacaa cattgttaat catagtttac
    25981 cttcttacgc gtcaattttg acgatcatgt gacgaagaat gtcagcgttg attttggaaa
    26041 gacggtcaaa ctctttaaga gctgcatcgt catttgcttc aacgttaacg atgtggtaaa
    26101 gtccttcacg gaaatcttgg atttcgtatg caagacgacg tttttcccaa gtttttgatt
    26161 caacaacagt tgcaccgttg tcagtcaaaa tagagtcaaa acgtgctacc aaagcgtttt
    26221 tagcttcttc ttcaatgttt ggacgaatga tataaagaat ttcgtattta gccattgata
    26281 tgttcctcct tttggtctaa tgaccccaag actttgcaag gggtaagtga ggttcgctca
    26341 caataaacta ttatactaga aaaaattttt ttacgcaagt aaaaacacta gaattcgaaa
    26401 aaacgccaca tgggcgtttt cctgttctta tggtttgata cggtgcaaca tacgtgggaa
    26461 tggaatagct tcacggatat gttttgttcc tgctgcgaag gttaccatac gttcgatacc
    26521 gataccaaat cctccgtgtg gaactgtacc gtatttacga aggtcaaggt agaattcata
    26581 ttctgtacga tccatgtcaa gttcatccat cttagcgaca agggcatcgt aatcttcctc
    26641 acgcatagac ccaccgataa tttctccata gccttctgga gcaagcaagt ctgcacaaag
    26701 cacgcgctct ggatttccag gaactggttt catgtagaag gccttgatgg ctgctggata
    26761 gttcatgaca aatgttggca caccaaagtg gtttgaaatc caagtttcgt gtggtgaccc
    26821 aaagtcatca ccatgctcaa gatgctcgta gtcagcatct tcatcatttt catgctcttg
    26881 caagaggtca atggcttgat cgtaagtgat acgtttgaat ggctctgcaa tgtagcgttt
    26941 caagagttct gtatcacgtt ccaaggtttc caaggcttga ggcgcgcggt caagaacacc
    27001 ttgtagaaga gctttcacat aagcttcttg caagtcaagc gactcatcat gtgtcaagta
    27061 tgagtactca gcatccatca tccagaactc agtcaagtga cggcgtgttt ttgatttttc
    27121 agcacggaaa actggaccaa agtcaaagac acgaccaaga gccatagccc ctgcttctag
    27181 gtaaagctga cctgattggc tcaagtaggc tggcgttccg aagtagtcag tttcaaagag
    27241 ttctgtagaa tcttctgccg catttcctga aagaattggg ctgtcaaact tcataaaacc
    27301 attcttgtca aagaactcat aagttgcata gataatagcg ttacggattt gcaacacagc
    27361 tacttgctta cgagagcgta gccacaagtg acggttatcc atcaaaaagt ctgttccgtg
    27421 ttcttttggt gtgattgggt agtcttgaga ttcaccgatc acttcgatgt ctgtgatgtc
    27481 caactcatag ccaaatttag aacgttcgtc ctctttgaca atacctgtca cataaacaga
    27541 cgtttcttgg ctcaagcgtt tgataacatc aaacttctca agtcccactt cttcaccaaa
    27601 tttttcgaca aagtttggtt taaaagccac accttgaaag aaggctgttc catcacgcaa
    27661 ttgtaagaaa gcgattttcc cttttcctga tttgttggca acccaagcgc caatcgtcac
    27721 ttcctgacca acatagtctt ttacatcaat aatcgttaca cgttttgtca ttatttttcc
    27781 ttttcttttt tattctttat ggcaaaccac ctctatattg ttcccatcca ggtcaatcat
    27841 aaaagcagca taataaatcg gatgctcact tcgataacca ggaaccccat tgtctcgccc
    27901 acctgcctct aagccagcct cataacaagc ctgaacttct tccttatttt ctgctaaaaa
    27961 agcaaaatga acaggatctt gtgttccctg agtcagccaa aaatcaccac caggatgagg
    28021 gctgttcggg gatagaaaac taattagaga actagtctta aaagtcaatt tatagtccaa
    28081 aggagcgaga aaactcctat aaaatccttc tgaaatttgt aaatccttta ccttaatctc
    28141 aaaatgatca atcattctca ctacccataa atgctttcaa gcgttcgact gcttctttaa
    28201 gcgtgtctag gtctgtcgca tagctgaggc ggacattttc tggtgctcca aatccagctc
    28261 ctgttaccaa ggccacttcg gcttcttcta agatagcagt tgtaaagtct gtcacatccg
    28321 tgtagccttt catctccatg gcctttttga catttgggaa gagatagaag gccccttgtg
    28381 gtttgaccac ttcaaatcct ggcacctctg caaggagggg atagatggta ttaagacgtt
    28441 cctcaaaggc ctgacgcatg ctttctacag tatcttgctc acctgataga gcctcaactg
    28501 ctgcatattg ggctactgct gacggattcg aagttgtttg acctgcaatc ttggacatgg
    28561 cagcgataat gtctgcttct ccaacggcat aaccaatccg ccaaccagtc atggcatagg
    28621 ttttagacac accattgatg accactgttt gcttgcgaat cgcttccgat aggctagaaa
    28681 tcggtgtgaa ctcatgacca ttataaacca agcggccata gatatcatct gctaggatga
    28741 gaatatcatt ttctacagcc cagtttccaa ttgccaagag ttcctcacgg gtgtaaatca
    28801 tacctgtggg attagatgac gaattcagca ccaaaacctt ggtcttgtca gtgcgagctg
    28861 cttctaactg ctctacggtc accttaaagt gattgtcttc cttagcagaa acaaagacgg
    28921 gaacgccttc tgccatcttg acctgatctc catagctaac ccagtatggg gttgggatga
    28981 tgacttcatc acctggattg accacagcca taaagaaggt atagagagaa tatttggctc
    29041 ccgcagcgac tgtcacttga tttgacgcta cagaatagcc gtaaaagcgc tcaaagtagc
    29101 tattgaccac cgccttaagc tctggcagac ctgaggttac tgtataaaaa gaagcacgcc
    29161 catctcgaat cgatgcaatg gcggcatctt ggatattttt gggagtagtg aaatctggct
    29221 cacccaaggt tagagacaaa atatctctac cctcagcctt cagtgctttg gcacgggctc
    29281 cagtagccaa agtcacactt tcttccattt ctaaaacacg gttggatagt ttcataggcc
    29341 ctccttattg accaatgctc ctgtttcaaa atctactaga taaaaatcag atcctgactt
    29401 aacttcccag attggcttgt cttgataacg accaaaggtt atcttgtcaa tctcgccagc
    29461 tcccttttcc ttagaaaccg tttctgcttt ttcttgtgaa ataccctgat ttagctgata
    29521 aacgtaaatc ttatggtcat ctttaccaat caggacagca agcgcttctt gctgtttatt
    29581 acgaccaaga acgctgtaat aagattccaa gccattgtat aaatcaacct gatcagcctg
    29641 ctctaatcct gcatactgct gagctaattt ttctccttca cttttagctg tttgataggg
    29701 tttcatgcta agagaaacca tatacagaaa ggaagcactg ataaccacaa acaaaatcgt
    29761 catccctaga ccatactgcc acagtagatt attttttgct ttgttttgtc tttttttcac
    29821 tcgtctattt taccatctat taagctttat tacaagtgaa tataagaata ctcttcgaaa
    29881 atctcttcaa accacgtcag ctttatctgc aacctcaaag ctgtgctttg agcaaccaat
    29941 tctatttctc ccttcaaaca aaaccgattt tgaaagtgaa acagttctta ctttttcagt
    30001 cacaaatgac tagagtttcc gaaattttac aattttcaaa taaactctga gcaaatttct
    30061 tgcaagttct tttgttttgt tgtaatatat tttataacaa cgagagagtt ctcgaaattt
    30121 taagaaaaag gagacacatc atgtctaaaa aagtattatt tatcgtcgga tcactacgtc
    30181 aaggttcttt caaccaccaa atggcgctcg aagctgagaa agcacttgct ggtaaagcgg
    30241 aagttagcta ccttgattat tcagcccttc ctctcttcag ccaagatttg gaagttccaa
    30301 cacatccagc tgtagctgct gctcgtgaag cagttctcgt tgcggatgct atctggattt
    30361 tctctccagt ctacaacttc tctatccctg gtacagtgaa aaacttgctt gactggctat
    30421 ctcgtgccct tgacttgtct gatacacgtg gcgtttctgc ccttcaagac aagtttgtca
    30481 cagtatcatc tgtagccaat gcagggcacg atcaactttt cgctatctac aaagacctct
    30541 tgccatttat ccgtacacaa ggcgttggtg atttcactgc tgcacgtgtt aatgactctg
    30601 cctgggcaga cggaaaattg gttcttgaag aaacagtcct aaactcactt gaaaaacaag
    30661 ctcaagactt ggtcgaagct atcaagtaac taacactcaa taaaaatcaa aaagcaaact
    30721 aggaagctag ccgcaagctg ctcaaagcac tgctttgagg ttgtagatag aactgacgaa
    30781 gtcagtgaca tatatacggt aaggcgacgc tgacgtggct tgaagagatt ttcgaagagt
    30841 ataacataat aaaagcgaac aagactactt ttctgacact cagaagacta gcttgttcgc
    30901 tttttttctc atttataaac taaaacagct gatgatacat attgccaaat acaaaatatc
    30961 tgatttctat acttccttta caaaaaccaa tccctgtggt tgtgacaaat cttctcggta
    31021 aacaaatcca gcaaagttca agcgacgtgc ttcccccaca gtttgtactt gattttctat
    31081 taaagctgtt agaaaggccc cgcgcgcttt cttggagata gttgagtgaa tcttcagctg
    31141 accgcctcta tcctccatga atttgaaggt caccatcttt gctctgattt ccttagaaaa
    31201 tacagtctca aactctgatg acaagagaga gaaaatcact tcttccttct tcagagcttc
    31261 atcatagact gccttccaat ggctcttcaa agtcttacca gcgactttta atttcatcaa
    31321 aaaatccaaa cggtgaggag ccatgggtga caaggctgga acaacaccgt acaaagccga
    31381 ggtaatgaag acatgatttt caagataatc ttgttccgcc tcggtcagct tatctctctt
    31441 aatgttgcgg tacataagcc catcaaaaag tttcaaggct ggatagtgtt gagcagtttg
    31501 ccttttcaaa gcttggatat tttgaaattc ttccgccgct ttctcagccg ataccttgta
    31561 gaaactctcc aattgactgg cagaatagag agccaaggca tcaagcacgg tctgactttc
    31621 tggttttaaa ggaattgcct cgatacttgg caagtctgtg ttcatttctt ttgctgttgg
    31681 gattaaaatt ttcatattga tagtgtagca tattttttag ccacaaccaa gaaattcatt
    31741 tgaaaaacct cggtttgacc gaggtttttc tatttatttg ggccatccta accagacagc
    31801 cacgagaaca agggctgtgc cagctaaact tgttaagata gataagaatt tatctttttt
    31861 ctccttgaac tgagaaaaac ctatcttcaa agcgagcagt ccgagtagca ttgaagcaac
    31921 catcaaataa aaacccattt ctttgtcctc cattaggctt aatttacctt attataacat
    31981 atatttatta aataaacctt
//
LOCUS       DAVKBC010000021        31877 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVKBC010000021 DAVKBC010000000
VERSION     DAVKBC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31877
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.021"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(107..265)
                     /locus_tag="VWX64_001139"
     CDS             complement(107..265)
                     /locus_tag="VWX64_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU9190617.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEEILVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(336..782)
                     /locus_tag="VWX64_001140"
                     /pseudo
     CDS             complement(336..782)
                     /locus_tag="VWX64_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(858..1070)
                     /locus_tag="VWX64_001141"
     CDS             complement(858..1070)
                     /locus_tag="VWX64_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9190618.1"
                     /translation="MTQLLLHADETSYRVLESDSQLTYYWTFLSGKAENQAITLYHHD
                     QRRSGLVVQEFLGDYSGYVHCNMLRQ"
     gene            complement(1079..1384)
                     /locus_tag="VWX64_001142"
     CDS             complement(1079..1384)
                     /locus_tag="VWX64_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HEU9190619.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(1371..1565)
                     /locus_tag="VWX64_001143"
     CDS             complement(1371..1565)
                     /locus_tag="VWX64_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9190620.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
     gene            complement(1762..2085)
                     /gene="tnpB"
                     /locus_tag="VWX64_001144"
     CDS             complement(1762..2085)
                     /gene="tnpB"
                     /locus_tag="VWX64_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU9190621.1"
                     /translation="MTIHLSILGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLTWLSTEKDIKALTSEQVDWLMKGFS
                     ITPKI"
     gene            complement(2069..2251)
                     /locus_tag="VWX64_001145"
                     /pseudo
     CDS             complement(2069..2251)
                     /locus_tag="VWX64_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2555..4117)
                     /gene="guaA"
                     /locus_tag="VWX64_001146"
     CDS             complement(2555..4117)
                     /gene="guaA"
                     /locus_tag="VWX64_001146"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU9190622.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4259..4957
                     /locus_tag="VWX64_001147"
     CDS             4259..4957
                     /locus_tag="VWX64_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9190623.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKYGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(5000..5898)
                     /locus_tag="VWX64_001148"
                     /pseudo
     CDS             complement(5000..5898)
                     /locus_tag="VWX64_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
     gene            complement(5907..6842)
                     /locus_tag="VWX64_001149"
     CDS             complement(5907..6842)
                     /locus_tag="VWX64_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU9190624.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6839..7564)
                     /locus_tag="VWX64_001150"
     CDS             complement(6839..7564)
                     /locus_tag="VWX64_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU9190625.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESIEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7648..8283)
                     /locus_tag="VWX64_001151"
     CDS             complement(7648..8283)
                     /locus_tag="VWX64_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU9190626.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8285..9112)
                     /locus_tag="VWX64_001152"
     CDS             complement(8285..9112)
                     /locus_tag="VWX64_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9190627.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINTLFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9134..10199)
                     /locus_tag="VWX64_001153"
                     /pseudo
     CDS             complement(9134..10199)
                     /locus_tag="VWX64_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813133.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10712..11323
                     /locus_tag="VWX64_001154"
     CDS             10712..11323
                     /locus_tag="VWX64_001154"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9190628.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11368..12096
                     /gene="rlmB"
                     /locus_tag="VWX64_001155"
     CDS             11368..12096
                     /gene="rlmB"
                     /locus_tag="VWX64_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU9190629.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12134..13045)
                     /gene="trxB"
                     /locus_tag="VWX64_001156"
     CDS             complement(12134..13045)
                     /gene="trxB"
                     /locus_tag="VWX64_001156"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU9190630.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13111..13335)
                     /locus_tag="VWX64_001157"
     CDS             complement(13111..13335)
                     /locus_tag="VWX64_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU9190631.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13413..14156)
                     /locus_tag="VWX64_001158"
     CDS             complement(13413..14156)
                     /locus_tag="VWX64_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9190632.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMPFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFTSYKRTYI"
     gene            complement(14156..14956)
                     /locus_tag="VWX64_001159"
     CDS             complement(14156..14956)
                     /locus_tag="VWX64_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9190633.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15114..15470)
                     /locus_tag="VWX64_001160"
     CDS             complement(15114..15470)
                     /locus_tag="VWX64_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU9190634.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15464..15994)
                     /locus_tag="VWX64_001161"
     CDS             complement(15464..15994)
                     /locus_tag="VWX64_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU9190635.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGESQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(15994..16488)
                     /locus_tag="VWX64_001162"
     CDS             complement(15994..16488)
                     /locus_tag="VWX64_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190636.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16623..17069
                     /locus_tag="VWX64_001163"
     CDS             16623..17069
                     /locus_tag="VWX64_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU9190637.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            17066..17713
                     /locus_tag="VWX64_001164"
     CDS             17066..17713
                     /locus_tag="VWX64_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU9190638.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWILMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(17734..18315)
                     /gene="pdxT"
                     /locus_tag="VWX64_001165"
     CDS             complement(17734..18315)
                     /gene="pdxT"
                     /locus_tag="VWX64_001165"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU9190639.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESYLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18316..19191)
                     /gene="pdxS"
                     /locus_tag="VWX64_001166"
     CDS             complement(18316..19191)
                     /gene="pdxS"
                     /locus_tag="VWX64_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU9190640.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19343..20722)
                     /locus_tag="VWX64_001167"
     CDS             complement(19343..20722)
                     /locus_tag="VWX64_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU9190641.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            21016..21939
                     /locus_tag="VWX64_001168"
     CDS             21016..21939
                     /locus_tag="VWX64_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU9190642.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVNGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21999..22604
                     /locus_tag="VWX64_001169"
     CDS             21999..22604
                     /locus_tag="VWX64_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9190643.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22623..23867
                     /locus_tag="VWX64_001170"
     CDS             22623..23867
                     /locus_tag="VWX64_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9190644.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGINAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24090..24347)
                     /locus_tag="VWX64_001171"
     CDS             complement(24090..24347)
                     /locus_tag="VWX64_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU9190645.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24389..26425)
                     /locus_tag="VWX64_001172"
     CDS             complement(24389..26425)
                     /locus_tag="VWX64_001172"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU9190646.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26685..27602)
                     /gene="glyQ"
                     /locus_tag="VWX64_001173"
     CDS             complement(26685..27602)
                     /gene="glyQ"
                     /locus_tag="VWX64_001173"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU9190647.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISNQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(27797..28558)
                     /locus_tag="VWX64_001174"
     CDS             complement(27797..28558)
                     /locus_tag="VWX64_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9190648.1"
                     /translation="MENLYLVKDDSQLAAFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSNFNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICTQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWLSFLIVDKLVENLG
                     SVQAVFDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28831..29673)
                     /locus_tag="VWX64_001175"
     CDS             complement(28831..29673)
                     /locus_tag="VWX64_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU9190649.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29787..31178)
                     /locus_tag="VWX64_001176"
     CDS             complement(29787..31178)
                     /locus_tag="VWX64_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU9190650.1"
                     /translation="MDKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKKHFRKGQAEVIAYYPIQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31413..31793)
                     /locus_tag="VWX64_001177"
     CDS             complement(31413..31793)
                     /locus_tag="VWX64_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU9190651.1"
                     /translation="MTCQFIRDMLDLPAKNVTILEGSDIHVLPSMPYSAQDFYTSIDD
                     VLAELDNGTQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKHIAP
                     VYAIAIVDSNYFSDDLAFHSFIVK"
BASE COUNT         9409 a         7118 c         5731 g         9619 t
ORIGIN      
        1 atgatatggg attttcatat aataaattgt aaccgcccaa taacgaagta tattgaaaaa
       61 tctccagact agagaactca cggatagttc ctaatctgga gatttcttat ttgcactttt
      121 cttgtacaac tttagtccat ggtaaatagg cctctaaaac ctctttgttt acgagaattt
      181 cctcgtttgg aagacattct agaagatagg atagatattt ctcactattt agttgatgac
      241 gtttagctgt ttccaataag ctcataataa tagctcttgc tttagctcct tcaaaacttt
      301 gagaaaataa ccaccctcgc ttttttaaac tgagctcagg ctaaaagagt ccactggact
      361 cttttactcc gtcccataac caatgactta atggcgcgtt cagctagatt attggaaagg
      421 accagatgtc cgtctttcaa aatagtctta aaggtttctt catacttgag gctgtattca
      481 attgcccttc ctagttttga acccgataaa actgactgac gccggcacca agcaaagaaa
      541 tcttccatta ggggttggag ctcttcttga cgtttctgta gtcgttcatc agctgacaat
      601 gtctcccagt ctctttccaa ggcaaataac tgatcacaat aggctaatcc tttagctcct
      661 aaggatgatt tatccgcttg cttgggggtc gcttcaaaaa acttccttct cacatgtacc
      721 caacatccaa caagttcagc ttcttccagt tgacgataag cttctagcgg ttcgcagttt
      781 accaagctta gcgtcgcctt gctcctaagc cttggactgc tatcgcatag gcagaactag
      841 aggactaaag ttctaagtta ctgccgcaac atattacaat gcacatagcc agaataatct
      901 cctaggaatt cttgtactac taaaccactc cgacgctgat catggtggta cagcgtgatt
      961 gcttgattct cagctttccc agacaaaaaa gtccaatagt aagtcaactg actatcactc
     1021 tctagaaccc tataagaagt ttcatccgca tgaagtaaga gctgagtcaa tagtctcgtt
     1081 ataaaggggc tttaggaata ggagctttca cgattttatc actcggattt ttatcactgc
     1141 atgcttggca tttgtaagcg tgttggatat gatctatgcg ttttaattgc gcaggaataa
     1201 agactaattc ttgtcgttga agggttgctc caatctcttt tagatctccc tgacaatcag
     1261 agcaaatgct ctcttctact tgatgatgaa cttcttctga atcaaattgg gcaagaagag
     1321 cttggcgttt ccctttagat ttcttacgtt tgtaggtaat ttcctctgtt tcaactggga
     1381 acatctccat cttcctcaga tggagactct tcctcaaaaa ggttgagttg tccagagggg
     1441 caaacacttt tctcagagga ttttccatag agcttttgag tcagataagc cacttgttca
     1501 cgcagaaggg caagttcatt ggtgagacta tcaattgtag cactctgttg ttgaatgatt
     1561 ttcaatcttc ttccatgagc ttccctctct gttttctaac tttattatac taaaaagaaa
     1621 gtcctcattt caatagaaat cacgactttc tgatggattt atagtaaaat gaaataagaa
     1681 caggacaaat cgatcaggac agtaaaatcg atttctaaca atgttttaga agcagaggtg
     1741 tactattcta gtttcaatct actatatttt tggagtgata gaaaagccct tcataagcca
     1801 gtctacttgt tcagatgtga gagctttgat atccttttct gtacttagcc aagtcagtct
     1861 gccgttctca aagcgtttat atagtagcca aaatccttga ccatcccagt aaaggacttt
     1921 aaagcggtct ttacgtccac cacaaaagag aaagacttga ccggagaaag gatccaattc
     1981 aaagtgggtt ttaaccagat aagccagtga atcgattcct tgtctcatat ccgttttccc
     2041 acacacgaga tagacctgcc ctaggataga tagatgaatt gtcatagagc aacaccttat
     2101 ccaaaagctg ttctaccatt tcgagattga gagattgaaa aaaacttact tcaagcttgc
     2161 caatacgaat tttaagcaga atatcatttc tctttttaga atcaaaacga cgagattgtg
     2221 gaatctctac aggaacaata ggttgtggca ttaaaatatc ctccaatagt tttactttac
     2281 taatagtata caggaggagc tccatgaatg atagatacct tgttatgacg cgcttactat
     2341 attagaaagt tggctctcta attaaattaa ttctcattat atatatcaaa agaccgcagc
     2401 ttgaaaacta cggtctaatt ttttgtccaa atgtaaacca cttggaacta ttattcaatt
     2461 tattcttttt agtaaatgtt cccgttttaa tcccagttac agtttttaat cctctgtaac
     2521 cgttgatttt acaaagcttt taattttttt gcgattattc ccactcaact gttgcaggtg
     2581 gtttacttgt aatatcgtag acgatacggt taacatgatc cacttcattt acgatacgta
     2641 ctgagatttt ttgaagtact tcccatggaa ttttggcaaa atcagcagtc ataccatcga
     2701 tagaagtgat agcacggatt gcaatcgtgt agtcatacgt acgaccgtca cccataacgc
     2761 cgactgaacg aacgcctgtg ttaacagtga agtattgcca aatatcgcgg tcaagtccag
     2821 ctttagcgat ttcttcacga agaatagcgt ctgattcacg aacggtttca agtttctctt
     2881 cagtgatttc acccatgaca cggatagcaa gtcctggtcc tgggaatggt tggcgccata
     2941 cgatatggtc tggcatacca agctctgtac caagagcacg aacttcatcc ttgtaaagag
     3001 tattgagtgg ttcaatcaat tcaaactgca tatcttctgg aagaccaccc acgttgtggt
     3061 gtgacttgat agtttgagct gtatccgtac cagactcgat aacatctgta tataaagtac
     3121 cttgagcaag gaatttcaca tctttgagct tgcttgcttc gtcatcgaat acatagacaa
     3181 actcgttacc gatgatttta cgtttttgtt cagggtcaga aacgccagca agtttgtcaa
     3241 ggaaacgttt agcagcgtct gctttgacga tattcaaacc aaacttacca ccgagcatgt
     3301 ccataacttg atcagcttcg cctttacgaa gaagaccgtg gtctacgaag atacagatca
     3361 attgatcgcc aatcgctttt tggagaagaa ccccaacgac agatgagtca acaccacctg
     3421 atagaccaag aaggacacgt ttatcaccga cggtttcacg aatttttttg atctgcatgt
     3481 caatgaaatt atccattgac cagtcacctt tagccttaca aatgttaagg gcaaagttac
     3541 gaaggatatc atttccgtat acagaatgac gaacttctgg gtggaattgg ataccgtaaa
     3601 tgtgtttatc tgggttttcg atggctgcgt atgggcagtc agctgatgta cctgtacgaa
     3661 caaagtcagc aggaatctca gtaaccgcat caccatggct catcaaaaca gtctgttcat
     3721 caggtgttga ttcaaaaagc gctgatggtg tgtgagttag ggttgattga ccgtattcac
     3781 gatttccagc atcacctgca ggaacaactt ttcctccaag tttatgggtc aataactgca
     3841 taccataaca gattcccaaa attggaattc ctagttcgaa gatttctggg tcaatgtcaa
     3901 atgaaccatc ttcatataca gaatttggac cacctgatag aataattcct acaggattga
     3961 cttcacgaac ttcagcagct gaaattttat ggctttttag ttctgaaaaa acaccaatct
     4021 cacggatacg gcgtgaaatc agctggttgt actggctacc atagtccaat acgatgattt
     4081 tttctacatc ttgcaaatca gttgaaatgt tgctcatctt tttcctttct caaaagaaat
     4141 atcttttctc aatattctat cacaaataag ggcgaattac caactaaaca aggcgaagtt
     4201 tgactttttc tagtttattg gggtacaata gagaaaagat agaaatgaag tgaaaaatat
     4261 gctacctgct tatatgaaaa tccatgatca gataaaaaag gatattgacg agcaccgttg
     4321 ggctattggt gagaggcttc ccagtgaaag agatttagct gagcagtttg cggtcagtcg
     4381 catgaccctc cgccaagccg tatctctatt agtcgaagaa ggcgtcttag agcgccgtgt
     4441 aggaagcggc acctttgttt ccagtactcg agtacaagaa aagatgcgag ggacaaccag
     4501 ttttactgaa attgtcaaat cccaaggtaa agttccctct agccagctca tttcctacaa
     4561 aaaaaccatt cccaatgagc aagaagttgc caagctagga atttttccaa cggacaatat
     4621 tatccgaatg gagcgggtcc gctatgccga ccaagttccc ctagtttatg aagttgcttc
     4681 tattcctgaa aaattcatta aggactttaa aaaagaagaa atcaccagtc atttcttcca
     4741 aaccttgcaa aaatatggct atcgtatcgg caaatctcaa cagaccatct atgctcgcct
     4801 tgctaaagaa aagattgccc actatttgga agttgaaaaa ggacatgcta ttcttggatt
     4861 gacccaggtt tcctacctag aagatggtac tgcttttgaa tacgtaaaaa gtcaatatgt
     4921 aggcgaacgc tttgaatttt atcttgaaaa taattagatt accacgcaaa aactctctgt
     4981 cacagacaaa gagtcttttt tatttttcta agaataaatc tttcaaagaa atcaaagtta
     5041 cagcaaacaa tatcattgcc ataccaataa aatcaatggg ataaaattgt tcattcatta
     5101 ttaagaaggc aaagaaaacc gccgatattg gctcaattga agccaacaag cttgacttga
     5161 ccggtcctat cagactggct cctttaagga aagctgtata ggcaaagaca gtcccgataa
     5221 ggataatgcc tgcaaacgca aggagaaaat caagactagt cgggatatcg gcctgtagaa
     5281 tccctgtaaa aggaagggcg accaaacctg ctatgaccat tcccacacca atgaccaagc
     5341 tgctccccca ctttttaatc aaggctatgg gtaaaatgat atacaaagca taagtcaagg
     5401 cagaaaagag accccagaac agaccagcag gtgtcatgga taactggtcc aactgcccat
     5461 gtgttgcgat caggaaggtt cctccgatgg cgaatatgat ggaaactatc tctcccagtg
     5521 tcggtgccac cctatccttg atacagcgct ataaattaaa attccgacag gacaaacata
     5581 ctgaagcacc gtcgctgttc ccgcattggt ctcctgaata gcagacagat aggcgaattg
     5641 gttgagaaaa agaccaatca gagcaaaaat aagaagagac agcaaactct ttctatcctt
     5701 taaaaagacc agtattttat cctttgcagt agcataagcc aagagcatga gaattccacc
     5761 agcgattaaa agacgcaagt tggtcaagac cagagccgaa attccgtgtg ccattaggta
     5821 ttggccactc gttcctgaca acccccaagc aataccagcc acaactgtta gtaaagtccc
     5881 ttttaaacta tttgacatgt ctctccttac tcttctttgc gaatcaagtt catcacttga
     5941 ttgcggtcta atatccattg agctctctcg tccttttcat aggtacgatt cgataggaaa
     6001 atagtggctt cttgcttctg acgattccac atgataaagg tacctgtata gcccgtatgg
     6061 tctagccaat ctccttccaa attccatgct aaagaacgtt ccttgtcatc caaaggagaa
     6121 aaattttgat ttaagtctct tgcaaaatca tctgctaaat agtgttctaa aaagatttgt
     6181 aaatccttta tagtcgaaaa taaaccagca ctcccagcat gtctacccag gagacgagcc
     6241 ttgggatcat gcactatgcc tgcctctaca cctctaactg ttggaacagc aagctcaact
     6301 ggcccaaact tggtttccgt cattccccaa ggtttccaga cttgatcctt taaaatcaca
     6361 tccaaatctt gattaaaaat tctttccaaa ataaagccca acagcaaaaa atggacatcc
     6421 gaataaagaa aggctggctg acttcgtctg ttgagatgaa acatcgcttc ctttaattca
     6481 ggggctgtta aaagatcacg attaggaata aaaggatcaa ggtctgttgc atgagtcaag
     6541 agctggcgaa tagtgatgtc tggataatca ctctcaggta aaaaatctat taccagtcta
     6601 tcaatatcta attgacctat ttcccacaag aaggtacaaa ctgtgccaac cccaacaacc
     6661 ttgctgacac tagctaggtc ataaactagt cctgcctcag tctgcaagcc atgctctggg
     6721 tcactctggc ctaaatagaa ctctgtccat tgattgtcct taaaatacgc aaaagaggct
     6781 ccgggataaa tccctgcctc gatttgttct tctatttttt taataatctt ggtccacttc
     6841 atacttcttc aaaccacaat tcaacattat ttctatcttt accaaggaag aatttttcag
     6901 acttaggaat aaaatattca atagactcaa acttctggcg aagacttgct atgtctaatt
     6961 cattgaccaa gaacttgagc atagataagt cccaggtaac cgtattgtcc acagtcaaat
     7021 cctgcccctg agctggaata aaatcaaggg atgccccaat ttcagatgat tccaagaaac
     7081 tttcgatatc agttgggaga tgtaattcca tagaaatctc aaatttactt aaagaaattg
     7141 atgccaaatc tgtttgaaat tcaggctttt ctcctacttc tactagactt gctctgtcat
     7201 cttccgcatg aatcaaaatc aaatcatctt ctggtgagaa aatttcaaaa gcgtagccat
     7261 tttgaccttt atataatcga tgaatcgaat ctgttttaga taagattcct tcaatttcta
     7321 agggattttc caccttgaca atcaatctag ctagtttttt tcttccctct accttacgag
     7381 tacgcatact gggagcttct tctaaaacca gcttttcaag acccgtttgg tcacctagtg
     7441 acagaaaggc cgattcttct aacaaggcct tcattccaag ggtttcaata taaaatgttt
     7501 catttaattt tctattatta gcttttaaag taggaataat ccgtacaatc tgatttacat
     7561 tcataaattc ctccgtcact ttttatttta aaggatttta gaatttttta caagatatta
     7621 tgctcaaatt taacattatt tagctattta gtaaagatag tctttcaagg cttttgacaa
     7681 agcctgataa ccagcaatac tgaggtgcag tccatcagtt gtatattctt ttttgagttg
     7741 gcctgcttgg tctgtcaaac aatcaaatac tggcacaaat tccacctgca tataggcaga
     7801 tgcaagctct tgataggctt gattccagtt ctgaattttt tcattcgagc ggatatagac
     7861 tgcctgctgg tactcctctc cctcattgac aggcaaaatg gaaagcaatt taatctctgt
     7921 caatggataa tcgcgagcaa cggattgaat gatagcttcg agattattga gagcctcatt
     7981 cacaggaaca tcctttccga tatcatttgt cccaatcaga agaaaaattt tatctactgc
     8041 tccaccatat agatgagcat caaggttctc tagtaacagt cctgtctgat agccacgaat
     8101 tcctcgattg acaatcgtct ttgaagtccc aaatagctcc tgtagaggat aatactcgac
     8161 aatggaatcc ccaataaaaa gaatgtttgg ttctacaaca gaaatgtgat ttaggtgacg
     8221 atacttggtt tgaatttttt cttgttcctt taggagccaa ttttctaata actgtactgc
     8281 cacttcattc tcctttttct aaccagtttt ccaagacttg ataaactcct ccttggctgt
     8341 tggctggtgc tagagcagtc gccacagctt tggctttctc atcagcattt tccatcgcat
     8401 aggcaattcc agccatttca agcatttcaa catcattttc actatcacca aaagccatga
     8461 tttcttggga tttcaagtcc cagcgcttga gtaattcctc caagccccat gctttatgaa
     8521 tcccagcttg gaggatatca atgcaaccat agccactgga tacagctcgg acacggccat
     8581 caaagagagt attgatttct tccaaaaccg aactcaaacg ttcctcacca acaaccatgc
     8641 tcatcttgag cacaccacca aagaggtcag atgttaattc atccacaaat tgcatccgtt
     8701 ggtagaattt ttcaatcatt tctggagtca taaaactttc aagatctgta aaaatcgtac
     8761 cttccttgac aaaatcaccc ttcatccccg ttacaacaaa ctggtcctga cacgctcgac
     8821 ccttgaaatg agccaaagcc ttgttgacaa tggcgtcatc ccatgtctga gcctgaatca
     8881 attcattgtt ttcaaaaata cgagcgccat tagcaacaac cagaaccact cgatccacca
     8941 agggactcag tagttgtctc atgcggtgaa tttcattgcc cgtcgcaatg acaaaacgaa
     9001 tgcccctttg atccaactga tctaaaatct tttccaatcg tgggagatca agctgacctc
     9061 tagcatccag caaggtccca tccatatctg tcgcaattac cttaatcatc atttactttc
     9121 ctctggattc aaactaatac cacttcaatc ccacatgttc attcatttct ttataggctg
     9181 tatcaattcg ttccttagtc gcttcatcta actggtcacg atgactgcca tcctctataa
     9241 aatcttccaa aatataagtt tggtaatgat acaagggata tccttctggt gaaaaggttc
     9301 cctttggtgt tcgattgacc caagtaggat gatctttagc tgttccgata gttgtttttc
     9361 catcattctt cttgatggtg acatccatga gaacaccacg ttcagtccac ttagcattct
     9421 cttcatctcc catagattca attcgttgat tggaaatgaa gttccccatt gaatagataa
     9481 tgagtttctt atctccatct ttttcaaccg tttcagatgg ctcaacaacg tgaggatgcc
     9541 ctccaaagat aatatccgct ccccaatcga tcatcttgtg ataaagagct ttttgttctt
     9601 cagttggttc caatcgatac tcaacaccca tctgaggcat gataatggtg atatctgctt
     9661 ccttctctgc ccgttcaact tcagccttca tcttatcttc gtttaaatct aaaagataac
     9721 gattatagtc ttcctgagaa atatactgct caattccatt gaaaccatag gaataggctg
     9781 acaatgcaac cttgatacca ttcacttcct taatgaccag cggaacctga tcacgtggtt
     9841 cgtgcgtata aactccgatt ggagtgattc cagctttctc aataatatcg gccgttgaaa
     9901 taactccctc aatttgcgaa tccaaaatat gattatgagc taaatccagc acatgataac
     9961 ctgcctcctt aatagcatcc ataacttcag caggagcatt aaagagagga taacccgcta
    10021 aataatgatc cttattaatg gtttcttcaa aatcaccaat agctaaatct gcttgcttag
    10081 tccacttgct tgagccaagg agtcacatac tcaaaatttt catgaaagtc ataggtaccg
    10141 tcttcttttt tagctgaaaa gaaaagtcca tcgtggtaga gcaaatcccc gtgggccata
    10201 attctggcag ttttttcctc ttcctactcc tgagactttt gcttagtccc ctcttgagaa
    10261 atagtatctc gtttttgact agtcaaggga ttccttggaa gctttcaaac aacaagacca
    10321 agcccattga taaaccaact gctagcaaga gtatcgccac aaatccctta ttgctccact
    10381 tgcgataact cctaaaaagt ttaccaagcc cttcataaaa cgaaaagcta aaccaccctg
    10441 atttcgattt tgtcttcttt gtatcttcgt tctccctact ttcttatgca agccttttct
    10501 ttttattata tcacagataa gtatttcttt cacaattgaa ttgaacttcc catctatttt
    10561 ctataaatcc taaatgccat aatgctttca attcttgtca ttttgtgata tcatgtagag
    10621 gaaatgaact aatccacagt ggcttattcc aagtatacca cttgggcttt ggcagtagct
    10681 aactgcacta aacataatat aaggagagaa aatgtctgca atagaacgta ttacaaaagc
    10741 tgctcactta attgatatga acgatattat ccgtgaaggg aatcctactc tacgcacggt
    10801 tgctgaggaa gtcactttcc ccctatctga ccaggaaatc atcctaggcg aaaagatgat
    10861 gcaattcctt aaacattccc aagatcctgt catggctgaa aaaatgggac tccgcggtgg
    10921 tgttggactg gctgctcccc agttagatat ctcaaaacgc attatcgctg ttttggtacc
    10981 taatattgtt gaagaaggcg aaactccaca ggaagcctac gatttggaag ccattatgta
    11041 caatccaaaa atcgtctctc actctgttca agatgctgct cttggcgaag gagaaggttg
    11101 cctgtctgtt gaccgtaacg tgcctggcta tgttgttcgc catgcccgcg ttactgttga
    11161 ctactttgac aaagatggag aaaaacaccg tatcaaactc aaaggctaca actccattgt
    11221 tgttcagcat gaaattgacc acattaacgg tatcatgttt tacgatcgca tcaatgaaaa
    11281 agacccattt gcagttaaag atggtttact gattcttgaa taaagaaaat cccgttgcaa
    11341 gacggggttt tgtgttataa tagaggcatg aaaacaaatg atattgtcta tggtgtccac
    11401 gccgttaccg aagccctcct tgcaaataca ggaaacaaac tctacctcca agaagatctc
    11461 cgaggtaaga atgttgagaa agtcaaggaa ctagctacag aaaagaaggt gtccatttct
    11521 tggacatcaa aaaaatctct ctctgagatt actgaaggtg ctgttcatca aggttttgtt
    11581 ctacgagtgt ctgaatttgc ctatagcgag ctagattaca tccttgcaaa aacacgccaa
    11641 gaagaaaatc cacttctatt gattctagat ggtctaaccg atccccataa tctgggttct
    11701 atcttgcgaa cagccgatgc gaccaatgtt tcaggtgtca tcattcccaa gcaccgtgct
    11761 gtcggagtaa ctcctgtcgt tgccaaaaca gccacaggtg ctattgaaca cgttccaatt
    11821 gcccgagtga ccaacctcag tcaaacctta gataaactca aggatgaagg tttctggacc
    11881 tttggaacgg atatgaacgg tactccttgc cacaagtgga atacaaaagg gaaaatcgcc
    11941 ctcatcattg gaaatgaagg aaaaggtatc tctagcaaca tcaaaaaaca agtcgatgag
    12001 atgattacca ttccgatgaa tggacatgtt caaagcctta atgccagtgt tgctgcggcc
    12061 attctcatgt acgaagtttt ccgaaataga ctataaaaag tttccagtca tctgattgga
    12121 aactttttta taattaacta tgttctgtaa tgaatttata ggcttcttga ccagcgatag
    12181 ctccatctcc aaccgctgtt gttacttggc gaaggtcttt caagcgaaca tctccaactg
    12241 caaagatacc gtcgactgca gttttcatgt ggttatctgt cacaatccat cctgcctgat
    12301 cttggatatt caattcttta acaaaatcgc taagagggtc caatccaaca tagataaaga
    12361 caccaccgaa gacttgttct gtcacttgac ctgttttcac attttcaaat acgactgatt
    12421 ctactcggtt ttcacccttg atttccctta ctacagaatc ccagataaag ctgatttttt
    12481 cattcgcaaa ggcgcgatct tgtaaaacct tttgggcacg aagttggtca cgacggtgaa
    12541 caatggtaac agtcttagca aaacgagtca agaagagggc ttcttcaaca gctgaatctc
    12601 caccaccaac taccaataaa tcttggtcac ggaagaaagc accatcacac acagcacagt
    12661 aagaaacacc acgactgttc agttcttctt ctccaggtac tcccaaagga cggtgtttag
    12721 aaccagttgc tacgataact gtacgtgttt catatgtttg gtcatcagtc atcactttct
    12781 taaaatcacc atggtcttcg acattttcaa cataaccata aatgtgctca acaccaagat
    12841 tttcaagtgg ttcaaacatc ttttcagcca attcaggtcc actaatatta gcgtatcctg
    12901 ggtaattttc gatatcagat gtattattca tctgaccacc tggcagacca ccttcaatca
    12961 aagctacttt tagattgctt cgagcagcat acaaggccgc agtcatccct gcaggtccag
    13021 caccgataat aatagtatcg tacatataga ttccttcttt cttgttgtaa ctatctttat
    13081 tctaactctt tcttgtcaat cacgcaagga ttatgccttg aaaacaagaa ttaaactcat
    13141 aaccgcaaag gataatactg ggacaaccaa gactccaatc ataatcatat catagagatg
    13201 ggcttggcga gccttggctg tcttatcaac tcccgacatg gctctcagac caatccaaat
    13261 ccctaaaaaa atcagaacaa ggatggtggt caagatcaaa ctctcgaaat ataaagaaaa
    13321 tagttgcagt agcatgattt ctctcatttc tatctttttt aaagagtaaa ctcagctagt
    13381 ccaactaact gagttttcct ttatctatta tatcaaatat aagtccgttt gtaactagtg
    13441 aagaattctt ttgtccgctc ttctttaggg gtgtggataa tctcatccgg agttccagac
    13501 tcgatgattt tccccttatc taagaagaga attttatccg caacttgggc tacaaagggc
    13561 atgtcatgac tgaccaaaat catggtctga cctgacttag cagcatctgc aatagacttt
    13621 tctacttcac cgaccaattc tgggtcaagg gctgaagttg gttcgtctaa gagcaaaaca
    13681 tctggtttca tagcaagcgc acgcgctagg gcaacccgtt gcttctgtcc acctgataaa
    13741 tggcgaggat aatggttttc acggtccgaa agcccaacct tagccaactc ttccttggca
    13801 atcttagtcg cttcttggtc agataatttc ttgacaacaa ccaagccttc tttcacatta
    13861 tcaagtgctg ttcggcgttc aaataaatta aactgttgga aaaccataga caacttacgg
    13921 cgtagggcaa ggatttcttc ttgagtgatt ttagaaaaat caactgaaaa accatcaatc
    13981 tgaatagagc cactgtcagg tgtttcaaga taattgagac tgcgaagaaa ggttgatttt
    14041 ccagctcctg aagaaccaat caaggctaca acttcccctt tttgaatatc caagttcaga
    14101 tgatccaaga cagtctgtcc tgaaaaggat ttgcttaaat tcgaaatctt aatcattaac
    14161 gaaggtctcc tttcacatct gtttgcactg tatcaggtgc agaaatagcc atttttctct
    14221 cgatgaaacg accgaggctt tcaattccga tattgactac ccaataaaca agggcaacag
    14281 agatgaagcg ttcaaaatag cgataatcag ctccacctag aatctgagct tgggcaaaga
    14341 cttccacaac acccgcacta aaagctagag atgttccctt ggtcaaaccg atgagggaat
    14401 taatcaaggt tggagtagct accaccgctg cattaggaat aatcactcgt cgataaactt
    14461 gcgctcgggt catacccaga ctgcgcgccg cctcaatctc accaggatta actgagagaa
    14521 tggctgcacg aatggtttca ctagcataag ctgcctcatt aaaggcaaaa gcgacaatcg
    14581 caaaagctgc agctggaatc gcattgatat tgagaccagt tccccattgc tgattgaggg
    14641 ctttcaaagc caaagggatt ccgtagtagg tcaacatgag ttgcaccaaa atcggtgtcc
    14701 cttttaagaa actaacaaag aaggcctgca agggatataa aatcttgaca cgattgatct
    14761 tcacaatggc aaaaagaagc gccaaaacca agccaaaaag ggcaccgcca attgtcaaca
    14821 taattgttgt tggaagttgt tggacaattc tagggattcc atcaaagacc gaacgtaggc
    14881 taaacagctt gccatccgga atcaattgca tcaagttttg gtaccaatct gatgctaaaa
    14941 tcgttgtaac attcataaaa acatcctctt ctgataatga ttcattctac catgcttctg
    15001 ccgtcaatga aattatttgc tacggtcaga tacagacttt gtctacctac tagtttatca
    15061 tactttgaaa cagggaagtt atatatttta tctatcaaag agatagataa aaactatttc
    15121 agtcccagtt cttcataaga ttttcgataa ccgatttgct taacagttcc attttctact
    15181 aaaatgggcc gttttaacaa cataccgtca cttgctagca actcagccgc ttcttggttt
    15241 gacaaacttc ctaccttatc ttttagccct aattcacggt atttgatacc actggtgttg
    15301 aaaaattgct tcaattcaaa tcctgaggtt tctagccaat tcaaaatgac ttcttggcta
    15361 ggtgtttctt ccacgatatg gacggcttta tagtccacac ctaattgatt taattcttgt
    15421 tttgcttttt tacaagttga acatttgggg tattcgataa attctaacat gtgcttctcc
    15481 ttctattgtt tctatcttta aaatctactc cttcatgctc caagagccaa gctttctttt
    15541 ccactcctgc agcataacct gtcagacgct tgcctgctcc caacacacga tgacaaggta
    15601 ctaggataga ccaaggattg cgtcccactg ctccaccaat tgcttgagca gaagccactt
    15661 gcaggtcttg agcaatttgt ccataggtca ctgtctgacc ataaggaatt ccctgtaaat
    15721 aggaccaaac tctcttttca aaattcgttc caattggcgc caagagcaag ttggataaat
    15781 cctgagactc gcctttaaag taatcatcta agcaagcaat aactgggtct aaaataggat
    15841 gactaacaac ttcttctatc gtttcatctc ctagtcccct ctcaaaatgc ttctgctcct
    15901 gaacccaaat tccatacaaa taatggtcat cagctacaag tgatagaata ccaattggtg
    15961 aggagtagag tatttttaca tacttctttt gcattatttc tttaattttt gataggccaa
    16021 gcgttcgcca tctactggca ccttaccaac ttgtttaaaa ccaagttttt caaaaatatg
    16081 ttgcataacc ttgttttcag catgcgtatc tgagcgaaaa tcaagataat caaaaccttc
    16141 aatcaagccc tctaagaagg tttgagcaac tccttttccc tgcacatctg ctgccacagc
    16201 aatacggtga aagactagat actctgactc tccagcttgc cagtttccct cataaatagc
    16261 ttcataggcc tcctctggac tcttggtcac agcagcatag gctagcagtt ctccctcttc
    16321 caaggctacg taggcttgcc ctgagatgat atcatcgata ataacatctg catttggata
    16381 gccattttgc cactggtcac taccagcatc tgctaaacat tttttggcat cctccatcac
    16441 ctgcatgatg gcatctactt catttggaaa agctaaacga atttccatct tttttcctca
    16501 tttctgacta gtttctccca tcatagcata atttaagtat ttctacaagc agttaaaact
    16561 tgactttgtg tttttgttat tttataatct agttatcaaa actatataaa aaggagttga
    16621 aaatgaaaac taccttttcc tacccaaaat gggcagaaat tccaaacatt gacctctatc
    16681 tggaccaggt tttgctctat gtcaatcagg tctgcgcccc tatctctcct aataaagaca
    16741 agggcctaac agcatctatg gtcaacaatt atgtgaaaaa tggttacctg acaaagcctg
    16801 acaaaaaaaa ataccaacgc caacagattg cccgtttgat tgctatcaca accctcaagt
    16861 ctgtattttc tattcaagaa atagcccaga cacttaatac tctacaaact caagcaagtt
    16921 cagaccaact ctacgatgct tttgtggact atatgaacca aggaattgac ccagctaacc
    16981 ctattatcca aaccagctgc caaaccgtta aactctatca tcaaactcta gacttaatcg
    17041 atcatactca agaggaggta atccaatgaa cactagtctt aaactcagca aacaactcag
    17101 ttttggagag gagattgcta atagcgtgac ccatgctgtg ggtgcagtca tcatgcttat
    17161 cttgctgcct atttcatcca tctatagtta tgaagcacac ggatttttat cctctatcgg
    17221 cgtttccatt ttcgtcatca gtctctttct catgttccta tcatccacca tttatcactc
    17281 tatggcctat ggttcgaccc acaaatatgt tttgcgaatc attgaccatt ctatgattta
    17341 cgttgccatt gccggctcat acacgcccgt tgtcttgacc ttgatgaata actggtttgg
    17401 ctatctgatt attgtcatcc aatggggaac gaccatcttt ggtattctct ataaaatctt
    17461 tgctaaaaag gtcaatgaga aatttagcct tgctctttac ctgattatgg gctggttggt
    17521 tctggctatc attcctgcca ttatcagtca aacgacaccc gttttctgga ttctcatggt
    17581 aactggcgga ctctgttata cagttggagc tggattttat gccaagaaaa aaccttattt
    17641 ccacatgatt tggcatctct ttatcctagc tgcgtccgta ctccaataca tcgctattgt
    17701 ttattacatg taaaaaagtt gagaaattca atctcaactt ttttctttac acatattgat
    17761 aaagtactgg tgcaagcgca catcatcagt caattctgga tgaaaagaac ttaccaacat
    17821 atttttttct tgggctgcaa caatttgatt gttcactgtt gctagaattt ctacaccctc
    17881 accaacacta ctgataatcg gaccacggat aaaggtcatt ggaatcttgc caactccctt
    17941 acattctgct tccgtgtaga aacttcctaa ttggcgccca taagcattac gctcgaccac
    18001 catatccata gttcctagat aactctcttt ctgagaagtg atttccttag ccagcaaaat
    18061 taagcccgca caggtcccaa acactggtaa gccagataga atggcttctc ggatgggaag
    18121 tagcatgttc tggtcacgta agagcttgcc catggttgta gactcaccac caggcaaaat
    18181 caaacccgac aagtcactct gatcttgctg aaaatcatct agatttctga gttctacact
    18241 ctcgacacct aattgatcta gcacttttgc atgttctgca aaggcccctt gcaaggccaa
    18301 tattccgatt ttcatctatt ttcctcgttc agccatgaga atttggattt cattttcatt
    18361 aataccaacc atggcttctc ctaaatcttc agagatttga gctaggattt gaggattacg
    18421 gaagttagtc acagccttaa caatggcact cgctcgttta acaggatctc ctgacttgaa
    18481 aatacctgaa ccgacaaaga ccccctctgc ccctaattgc atcattaacg cagcatctgc
    18541 tggcgttgca acacctccag cagcgaaatt tacaactggc aattttccat gttcatgaac
    18601 atattggacc aattctacag ggacttgcaa atccttggca gcaacataaa gctcgtcctc
    18661 acgtaagttt tgaatgcggc gaatttcctg attcatcata cgcatatgac gaacagcttg
    18721 gacgatatcc cctgtccctg gttctccttt ggtacgaatc atggaagcac cttcagcgat
    18781 acgacgcaag gcttcaccca aatccttagc accacagaca aaaggaactt ggaattcttt
    18841 cttgtccaca tggaaacggt catcagctgg agatagaact tcactctcgt cgatataatc
    18901 aatttcaata gcctctaaaa tctgagcttc aacaaaatgc ccgattctga ccttagccat
    18961 tactggaata ctaaccgctt cttggatttc cttaatcatc tttgggtcgc tcatgcggga
    19021 aactcctcca gctgcacgaa tatcagccgg aattcgttcc aaggccatca cagctgccgc
    19081 accagcagct tctgcgatac gagcctgttc aggattctgc acatccataa taacaccacc
    19141 cttgagcatc tgtgccaagt ttttatttag ttcataacga ttttcagtca tttgttttat
    19201 cctcatcatt tgtattggta gctacctttt cattttaagt cagaacagaa tgaagcacaa
    19261 gataaaaaaa ctataattgt atggggacag attggctaaa aactatctga ccttaactta
    19321 aggccagata gctcattcat ttttattttt cagccgtaag ggcagccatt gtgatgtagt
    19381 tgtatggttt attgaagtgt ggcaagaaga agaggtctgt caatgccaat ttatcaattg
    19441 tcacatgctc ttggatagca agtgagaaca tgtggattcc catgctaatt gcaatatcat
    19501 gtgaaaccat ttgggcacca agaatttcac ggctatcttt gtcaaagaca atcttaattg
    19561 ctacttcatg gttgtcatgt ttcatgaatt ctggtttttg aagatcgtta aagcctgttt
    19621 cagttgcgtt gtaaccagca gctttcgctt tttcaagagt caaaccagtt gaaaccatgt
    19681 gaagaccgta gattgagata ccatttgaac cttgaacacc gattccttcc aattcatgtc
    19741 cacaagcgtt gtaggcacca acgataccag tgcgaacagc atttgaagca agagcgatat
    19801 agcttgtatc tttacgagca ttgtcataaa cagtcgcaca gtcaccaaca gcgtaaacgc
    19861 ctgggataga tgtttcttgt ttcttgtcta caaggaaggc accgttgcgg aagagttcga
    19921 tcttaccatc agcaagggct gtgtttggac ggaaaccaac tgcaaggata accatatcca
    19981 cgtcaaagct ttctttgtca gtaatcaagc gttcaacttt accatcacct tcgattgctt
    20041 taacagtttg acctagagcc aagcggatgt tgtgatcttc caagttcttc gccatcattt
    20101 gtgtgaagtc tttgtcatag taaccgttca agacagtatc aacgatatca acaaggacaa
    20161 cttcttttcc aagacgttca aaggcttcag caagttcaac accgatgtaa ccaccaccaa
    20221 caacggcgat acggtcgagg tgttggctct tgtcagaaag tttattgata acttcttcag
    20281 cattttggta caatttcacg aattgtacgt tttcaagagt tgctttaaat tcgcggtttc
    20341 ctttaacaat ttcaacacct tcgattggtg gcaagattgg tgtagaacct gtagcgaaaa
    20401 tcaatttttc gtatgattct ttgtgctctt ttccttcaac ttccgctgta actactttgt
    20461 tatcatagtc gattgaaaga acaggtgagt tcatgtaaac tttagcacct ttagcttcca
    20521 atttttcttt atcagaatag aacaagcctt cagcaccgtc aatttgttca ccaatccaaa
    20581 gagccattcc acatcctagg aaagagatgt tagagttttg gtcaaataca acaatttcgt
    20641 tctcatttcc aaaattatcc aacatggtat tgatacatgc tgtaccagcg tggttagcac
    20701 cgactacaac gattttactc ataaaaattt cctgccttca ttctaaattt accttactag
    20761 tataccattt accgttagcg tttacaaggg gggtactatt atttcagcat tttttatcaa
    20821 aaataattcc ccatttatcc tgttttcaag cctcatgaat tttatgagca tatttcttga
    20881 ctttttccaa attttgtttg tgaaaattct aactttatgg tattctaata acatgaaaat
    20941 aaaatgtaag ggcttcaatt tagataatta ttttatatta caacttattt tctataagag
    21001 aaaggagttg gtagcttgac tcttcgttca cattctgaac ggctaatggg gactactatc
    21061 actatttcat tagtggatga gcaagccgat atctttctcc aaaaatcctt tgacttgctc
    21121 aaagagcttg aataccgctt caacgccaat agtcaagaat ctgagttgat ggaaatcaat
    21181 tatcaagcag gaatatcccc cgtcacggtt catccagacc tgtttgagct gatttcactt
    21241 gggttagagc atagcctagc gctctctagc cacctcaata tcagcattgg tcccttaatt
    21301 caaacctggc gtatcggttt ttcagatgcc aaggtcgccc agcctcaaga aattgaatcg
    21361 gtgctgcctc taatcaatcc tcatggtatc gagttagatt cttctacttc tactgtgttt
    21421 ttaaaacaga aaggaatgaa gatcgatcta ggttgtttag ccaaaggata cagtgcggat
    21481 aaggttgccc aatttcttag gaaagagggg gtgacttctg ccttgatcaa tctgggaggg
    21541 aatatcctga ccattggaaa aaatcaggca agaggggata acccatggca aatcgggatt
    21601 caagacccag ccaatcctag gggaaatcat ttaatgacca tccctgttgt caataaatct
    21661 gtcgtgactt caggcattta tgaacgtcac ctgaccgtca atggacaaga ttaccatcac
    21721 atttttgaca gtcaaacagg atatcctgtt gaaacggaac tagcgagtct aacaatcatc
    21781 tctgataaat cagtcgatgg cgaaatctgg acgactcgac tctttggaga aagacctgct
    21841 tctatcctct ggcaagtcga aagtttggag ggcatcgaag tcatcctcat cgataaagaa
    21901 ggccacctaa gctgttcttc aggaattcct actctataga gacaactgtt tcaatggaat
    21961 tttaaaattg tattatgtaa aaagagaaag gaaatctcat gttaaaactt attgctattg
    22021 ttggaacaaa ttcaaaacgt tctacaaacc gtcaattgct tcaatacatg caaaaacact
    22081 ttgctgacaa agctgaaatt gaacttgttg aaatcaaggc cattcctgtc ttcaacaaac
    22141 cagctgacaa gcaagtacct gctgaaatat tggaaattgc tgctaaaatc gaagaggcag
    22201 atggcgttat tatcggtact cctgagtatg atcactctat tccagctgtt ttgatgagcg
    22261 ctcttgcttg gttgtcttat ggtatttacc cacttttgaa caaaccaatc atgattacag
    22321 gtgcttctta cggtacgctt ggttcatctc gtgcccaatt gcaacttcgt caaatcttga
    22381 atgctcctga aatcaaggca aatgttcttc cagatgaatt cttgctctca cactctcttc
    22441 aagcatttaa cccaagtggc gacttggttg accttgatgt tatcaagaaa ttggatgcca
    22501 tctttgatga cttccgtatc tttgtaaaaa tcacagaaaa attacgtaat gcacaagaat
    22561 tacttcgcaa agatgctgaa gactttgact gggaaaattt gtaagatagg agaccaaaaa
    22621 gaatgaaatt tgttggactt gttggatcaa actacgatca atcatataac cgtaagctct
    22681 tggaatttat ccgccgctac ttcaaactca aatttgaatt agaagttctt gaaattgacg
    22741 aagttccaat gtttaaccaa gatgaaaaat gggatgaaag tttccaatta cgttatttat
    22801 ataacaaaat tactcgtgca gatggtgtta tcattgctac tcctgagcac aaccacacta
    22861 tctcagcttc actcaaatct gtacttgaat ggctttcata cgaagttcat ccatttgaaa
    22921 acaagcctgt tatgattgtg ggtgcatcat actatgacca aggaacatca cgtgctcaag
    22981 ttcaccttcg taaaatcctt gatgctccag gtattaatgc ctacacgctt ccaggtaacg
    23041 aattccttct tggtaaagct aaggaagctt ttgataacaa cggaaatatc accaacgaag
    23101 gcactgttaa attccttgaa acttgcttag ataactttgt taaatacgta ggagtcgttt
    23161 cgaaattgaa aaaaccaaaa ccaatcgaat cagaagactt ggattgtgga aaaccaatcg
    23221 ctacaaccat cacagaagtt gaccctgacg atccagaatg ggtagaaaaa gttgcagcaa
    23281 tcactggtgc tgtttctggt gatacctatg tcaaattgga ccacggtatc ctaacagtta
    23341 accaaattga tatgttcttg aaagctatgc catttgaatt gacatacgct gatgacaaca
    23401 accaattcct ctactacaac aacgctcacc aagatccaga cactatgttc gctaaacgtg
    23461 taccacctca atcaggtagc cgtatgtcga ctgttcatgg ttctcttcca ccagcacgta
    23521 tgaagaacgt agagtgggtt atcggaacac ttcgcaacgg aaaccaagaa tacgtccgta
    23581 cgatcgttcc aggttctcct gcaggtgtta tcaacactca caactaccaa gcaatgtact
    23641 atcctgatgg atcatacgct ggtatcaatg aaatcgtctt taacttccaa ccatggcttg
    23701 actggtacct aaaagagact ggtcaacgtt tggtgggtgg tagcggacca tttgctcctg
    23761 ctgccggagg tcatggagac gccgatgcta cttctggcgc ttctgattca ggggatgctg
    23821 gaggccacgg tggtgacgca gacgctacag ccggtgcaag ttactaatga tagtttttag
    23881 gaaccattat ggttcctttt ttagcgaaaa aagactagca aacacaaact gctagtctct
    23941 ttgttatcgt ttcatctatc cttgttaaaa gaaagaatac ttatactcaa tgaaaatcaa
    24001 agagcaaact aggaagctag ccgcaggctg tacttaagta cggcaaggtg aagctgacgt
    24061 ggtttgaatt tgattttcga agagtattat tatgaatttg ggtcatcaag actacggcca
    24121 tgtaatcctt tttcacgttg tacttggcgt agtttttctg gtgtaacatc gtttccttct
    24181 tcgtccacaa ttttgattcc ttcaatgtgg tgacgaacag cgcggcgata accttcgatg
    24241 tactcctcac gtagtttggc ttgttccact ttttcttctg gtgttaaacc ttctgttttt
    24301 ttctttttag caagctcatt gatacgagca atttttttcg gatccatttc ttctcctttg
    24361 taataagata aagtccgttt atcaaatttt atttagtgtt aatttggtta aaacaagcaa
    24421 acttagctgc tttcttggtt agttgtgaca agattgccaa acgattttga cggacagcct
    24481 gatcttcagc cattaccata gtattttcaa agaaagcatc aatgactggg ctaagcgcaa
    24541 agagttgttt caattgctga cttgcaggtc ctgataaaac gagtgtttct actgcttctg
    24601 ccaaagcttt ttcttggtca ttctcaaata gtgctgaatc aactgtagca accccttctg
    24661 ccttctcagc caggttaaag gcacgagaaa gtgattcaac agatggttta aaatcttctt
    24721 ccttgcttac ttctacgaga gcacttgctg cttccaacat atctgccaca acaaagtttg
    24781 aacctgcaag aactgcttcc ttgatatctt ttggagtaga gcccatcatc ttatcaacac
    24841 gagccttgat aaagtccata acctctgctt tattttcata agtcaaactg tcaaatttca
    24901 atgcataaag gctatcaatc agctcatcca tagcaatgtg ccaaccaaag gcatccaaga
    24961 tacgaaccac accttgagtt gcacgacgaa gggcataagg gtcattagaa cctgatggaa
    25021 tcaatcctac tgagaagaaa ctcaaaatcg tatccaattt gtctgcaatg gctagaactg
    25081 caccgacctt gctctctgga agttctcctt cagctgatgt aggcatgtag tgttcacgaa
    25141 tagcagctgc caccgctgga gtttcaccag caagaagggt gtatttttca cccataattc
    25201 cttggagttc gtcaaattca ccaaccatac ctgtcaacaa gtcaaacttg taaatggctg
    25261 ctgcacgagc aaggtcaact gtttcatcca ctgacaaacc agctttttct gccaaaagta
    25321 cagtgatttg acccgtacga atcatgtgtt cacgaaggga accaatcttc tcatggaagg
    25381 tgacattgtt taatttttca acaagatctg aaatcaccaa tttttggtct tcacgccaga
    25441 agaattctcc gtcttccaag cgggctacca agactttttc atttcctttg atgacatttt
    25501 tcaaacgctc tgcgtttccg ttacgaacag aaatgaagtt tggcaagagt tttccatctt
    25561 gatcacgaac aacaaagtaa cgctggtgtt ccttcataga agttaccaag acttcttctg
    25621 gaacttcaag gtatttagca tcaaaacttc ccatgaaggc agttgggtat tcaaccaaat
    25681 tcaagacttc attcagcaaa tccgcatcaa tttcgatacg tacaccatgt tttgcctcaa
    25741 ttttcttgat ttggtcaaca atcatttgct cacgttcaca tggatctgcg attacaaact
    25801 gcttacgaag gtcttcttca tagctcaatg ctgactgaat tttggtttct ttccccaaga
    25861 aacgatggcc acggctcaca cgacctccct tgatatcaag gaaatccaag tcaaactctt
    25921 gctcatccaa gagaacagtt aaagtgtgaa cagggcggat gtattcaaag ctgtttccag
    25981 cccagtgcat gctgacaggg aaagtcaatg acttcaagac atctacaaca ccaggaacaa
    26041 tggcttcaac tgcttgacca acttcttcct tagtgacata gacatattct tcacccttga
    26101 tttcacggaa ttcgatatct tcaacagtca agccttttcc acggacaaat ccttgagctg
    26161 ctttggtgaa gtttccatca ctatccaagg caattttctt tgctggtccc ttgaaatctt
    26221 ctgtcaaatc agactgtttg tctgataaac cagtcacacg aacagccaaa cgacgtggtg
    26281 ttgagaaggt ttgaatggct tcaaaagaca ggcggttttc cttgaggaag gctgccattt
    26341 tttcgcctag ttgtttttca cttggtgtga caacataggc tggtaattct tcaagaccga
    26401 gttctactaa taagtttttt gtcatgtttt ttcctttaca ttttcttcaa tcttttttga
    26461 tatgcacctt aggtactggg gacgtcgcta actaactctg tgagtctgta tggaaatcca
    26521 atgctaaatt tatcaagatt tccaacaatc tcatcaaagt ggatttagct gactgatttt
    26581 tgaacctaag gtttcaaaaa tccccacata acagtacggc ggtgcatatc cctctagcaa
    26641 gtcttcgact tgcctctaac gattttagag tacagtatta ctcactattc tgcgtcttct
    26701 gctaaaagtt taactcgtgt ttcttcatcc aaaagtgggt aacctaggcg tttgcgttct
    26761 gcaacaaagg ttttggctac aacacgggcc aagttacgga tacgagcgat atagcctgca
    26821 cgctctgtta cagatacggc accacgcgcg tcaagcagat taaaggtatg tgaacatttg
    26881 agaacatagt cataggcagg gtgtaccaag ccttcttcta atgcacgacc agcttctttt
    26941 tcaaacttat caaagttttc aagcaacatt tcttggttcg aaatttcaaa tgaatatttt
    27001 gagtgctcat actcaggctg gataaagatt tctccgtatt ttacaccatc agcccactcg
    27061 atatcataga cagagtctac ttcttgaatg taagaagcca agcgctccaa accataggta
    27121 acttccgcag tcacagggcc agttgccaat ccaccgactt gttggaaata agtgaactga
    27181 gtgatttcca ttccgtcaag ccaaacttcc caaccaagac cagctgaacc agttgatggg
    27241 ttttcccagt tgtcctcaac aaaacgaata tcgtgctcca aaggattgat tcccaatttt
    27301 tccaaagact caaggtaaag ttcttggata tttgatggag aaggcttcat gaccacctgg
    27361 aattggtggt gttggtagag acggttaggg ttttccccat aacgaccgtc agcaggacga
    27421 cgtgatggct ctacataagc tgcattccat ggctcaggtc cgatagcacg aaggaaagtg
    27481 taaggactca ttgttcccgc acctttttca ttatcataag cctgcataag catacaacct
    27541 tggtcattcc aaaattgttg caaagtcaaa ataatttctt gaaatgttaa tttcttagac
    27601 attgaatact ccttaataaa aaataatttc ttgcgacacg agtctgcctc gtcgattata
    27661 cgaggcaaga cgagttagta ctgcgtctag ctcaggcact ctagtgctga gcgtggagca
    27721 gcccgactgt aaggaggtct ctgccactga tgcagtgaaa tgttaatttc ttagacattg
    27781 tttactcctt tagtttttat atttcttttt caattaattt ctgctgaaca aaccaatcta
    27841 acaagggaaa agttttttct gtatttgccc atagatgata agaatcaaag accgcttgta
    27901 cactacctaa attttctacc aacttatcta ctatcaaaaa actgagccaa tattcataaa
    27961 aaatacttgc atagttctta tcataagtcg aagaaccaaa atcattcaat gaatgccaac
    28021 catacttctt ctgaaaaagt tctactagag attgagtaca aattttttcc gcttgaaatt
    28081 cctcttctgt caagaaatac ttgcgactaa tatattcaac catcccctct tcgaaccaga
    28141 tataagagtc ataaccatca aaatcatcta aaaaatgctc cgaccaatga gctaactcat
    28201 gtcctacaat ctgtaagagg aaattttcag ataaagaatg atagtgactt tctattgctt
    28261 gagtttgctg agaacactcg tagtccatca attgatacaa atacaactct ttccaaacag
    28321 ctaaatcagg cgtcataacc attcgtctat tatttgtata ggctggaaca gcgctttccc
    28381 taataatctg tgtagcagca ttaaaatttg accaaataac ggcttgcggt aaatcacaga
    28441 ctgcaagttc attctttaaa aaagattgat aatctttcaa cttttcagta tttcttacta
    28501 caaaatcacg aaatgcagct agttgactat cgtcttttac aagataaagg ttttccacgt
    28561 ctctcctttc tttcacacaa tagactgaat aagcaaaaga accacatctg acaatcctag
    28621 gttgatttaa cctaggggcg tcagaaacgc ggttccaccc taatttatta cttcattgtt
    28681 tttgaaaata ctacagaaag cgccagctca ttattttgcc ctacttggct cccactgtcc
    28741 caagctcgct tgaagaacgc cataagactc tctttcctgc tgactattat atcaaaaatt
    28801 agaataatgt acaattcttt ttatgatttt ctagaaatcc acatcatcaa ctcgtggagc
    28861 acccgattga acagcaatcg tttttaaggt ttctctctcc tcatgactca gttcaattcc
    28921 aaaacaatca agattagctt gaatacgaga ggttgtgaca gattttggaa gtggtaaaaa
    28981 tccttctgcc aagctccagg ccaaggctat ctgagcaacc gattttccgt gatttgctgc
    29041 tatttcttgg acttgcttgc tatcaaacag ttctccttgt ccaaaaggcc cccaagcttc
    29101 caataaaatt cccttttcac gacagtaagc tacgacttga tcttgataca cacctggcgc
    29161 caagcgaact tgattgaccg caggaacgat agttgcagtt tcaagcaagg catccaaatg
    29221 atggggaaga aaattgctaa cgccgatagc acggattttc ccttcttgat agaggtcttc
    29281 catcgctctc caaacttccg cattgcgagt tttccatgcg tcattttctc tgagcggttt
    29341 tgggttcggc caatgaatca aatacaaatc caaataatcc aagcccagtt tttctataga
    29401 tttttccaaa gcttgacgag tttgctcata ggtttgctga ctattccaaa gcttggtagt
    29461 tacgaacatt tcttcacgtg gaactccgct atctttgatt gcttgaccaa cactttcttc
    29521 attctgataa atcgccgccg tatcaatatg acgataacca gccttcaagg cttctaacac
    29581 tgcacgatag gcttcttctc catccttagc cttaaaagtt ccaaatccca atactggaat
    29641 ttctactcca ttatttaatt gataggtatt catatgcttc tccttctatt ttattcatca
    29701 attatagcat aaaacatttt ttaagtagta ctatcttctg taaaaaataa gtctgtcaaa
    29761 tatctaacag acctattttt tcttgcttat tcatcacgac tatagtacag ctcatgagct
    29821 tttaggcgag tattgagcat ctctggtatg gtcacaaagg tataaccttg atttttcaaa
    29881 tactcaatga cccttggcaa ggcattgact gtcggactgt gaatatcatg catcaaaacg
    29941 atagagccgt tagctacttg atgctgaatt tctgtcaaaa tagatgcttc atttttactc
    30001 ttccagtcca gactatccac atcccacatg ataaagctca aatccaagct attgcgaata
    30061 tcatctgtaa tagcaccata aggtggacgc atgagtttag aactagaacc cagcacttta
    30121 gttagcacat cctcagtatc agtaatctgc tttttagctt catcaagaga gagttgcgag
    30181 agaatcggat ggctccaact atggtttcca acaacatgac cttcagattt tatcctcttc
    30241 accaagtcct cattcccaga aacatttttc ccaagcacaa agaaagtcgc tttaatatca
    30301 tatttagcta gggtctctaa tacctgcggg gtcgttgctg gatttggacc atcatcaaag
    30361 gttagagcga caactttttg atgtttctta tcaaagtaag attggtacaa ggccgcatct
    30421 ttttcgagta agtacgaaga ttggataaca tcaaagaaag cagatactgg caaggctatc
    30481 tcttctaaat tttcaaccac aggacttgga taaaggataa tctgactatc cttgtaatca
    30541 aaattccatg cagacaagtc ttggtcagag aagtttttta caatctgctc actctggtct
    30601 tgctctattt ttttatcctc tatgaaggag gtcaactctt ttatcagctg ttccttagcc
    30661 ttactagcat ctgaaaacag ttggtcaagt gtaaaaggtt gcccatcttc tgttaagtga
    30721 acctttccta gactggtctt ttcagtctct tcaatcttaa aagcaactaa atcatagatt
    30781 tgtttggtca cattacgatt aacgactccc tttaaacctg actcttcttg ctctgtatag
    30841 tagaaaacaa gattgtcctt actttctagc ttgtccttaa catcttgatt tatcagctcc
    30901 ctaacagagg aaatcacttt ctccccttgg atagggtaat aggcaatcac ttcggcttgc
    30961 cccttacgaa aatgcttctt ctgatttccc tcactcaatt gatcatcttt ctcttttttg
    31021 agcgattcaa tcttttgctc aaaacttttt tgctggtaga tcttaaaagc aataaatccg
    31081 cctaataggc aaatagaaat tgctaaaata ccaatcaaag ccaataatac atgtctcgtt
    31141 ttcccgtgtc tgccacgtcc cagtctactt ttatccatat ttatatcata acaaatttga
    31201 gaaataattt caatgataca atttggcaat ccacaattcc tctagcaagc caaagcatct
    31261 tacatcaact ccaacatccg tatctgtaga gattatgtag ttttctatct atggaatttc
    31321 tagtggattg aaactagaat agtagaccta tacttctaaa acattgttag aaatcgattt
    31381 gactgtcctg ttcgatttgt cctgttttta tttcatttta ctataaaact atgaaaagct
    31441 aggtcatctg agaagtaatt actatcgaca attgcgatag cgtatactgg tgcgatgtgt
    31501 ttgtagctct ggtgggtatc accttcacgt tgacggattt tttcaaggtt ttgattaacc
    31561 tgactgcaca gataagccca taggcgattg atgaaaaaat tttgatgatg aacctgaatt
    31621 tcgatgataa cttgggttcc attatctaac tccgccaaga cgtcgtctat actagtatag
    31681 aaatcctgcg ctgagtaggg catggaaggc aagacatgaa tatcgcttcc ctccaaaatg
    31741 gtcacatttt ttgctggcaa gtccagcata tcgcgaataa attgacaagt cattggtcgg
    31801 gctaatgccc ggatgtctta gaatcatcct tttcctcctt ctatagtgaa ttgaaataag
    31861 atgtgaacaa ctctatc
//
LOCUS       DAVKBC010000022        31012 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVKBC010000022 DAVKBC010000000
VERSION     DAVKBC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.022"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(1..683)
                     /locus_tag="VWX64_001178"
                     /pseudo
     CDS             complement(1..683)
                     /locus_tag="VWX64_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1057..3024)
                     /gene="tkt"
                     /locus_tag="VWX64_001179"
     CDS             complement(1057..3024)
                     /gene="tkt"
                     /locus_tag="VWX64_001179"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9190652.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAVLPTFLGGSADLAHSNMTYIKADGLQD
                     KYNPLNRNIQFGVREFVMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQELP
                     VTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQATWHHALTSTTT
                     PTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELVL
                     QGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVIG
                     IDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            complement(3061..3756)
                     /locus_tag="VWX64_001180"
     CDS             complement(3061..3756)
                     /locus_tag="VWX64_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU9190653.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKATIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            complement(3767..4852)
                     /locus_tag="VWX64_001181"
     CDS             complement(3767..4852)
                     /locus_tag="VWX64_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEU9190654.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIVGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILRKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            complement(4878..5189)
                     /locus_tag="VWX64_001182"
     CDS             complement(4878..5189)
                     /locus_tag="VWX64_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU9190655.1"
                     /translation="MKIVGVAACTMGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            complement(5217..5666)
                     /locus_tag="VWX64_001183"
     CDS             complement(5217..5666)
                     /locus_tag="VWX64_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9190656.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            complement(5644..6072)
                     /locus_tag="VWX64_001184"
     CDS             complement(5644..6072)
                     /locus_tag="VWX64_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9190657.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKPPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            complement(6065..7528)
                     /locus_tag="VWX64_001185"
     CDS             complement(6065..7528)
                     /locus_tag="VWX64_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU9190658.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKG
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFRMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCTDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFSELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSAFLTEGDKQRLQAKIQEINYE"
     gene            complement(8057..10393)
                     /locus_tag="VWX64_001186"
     CDS             complement(8057..10393)
                     /locus_tag="VWX64_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU9190659.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            10526..11275
                     /locus_tag="VWX64_001187"
     CDS             10526..11275
                     /locus_tag="VWX64_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU9190660.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTNKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            complement(11568..12182)
                     /locus_tag="VWX64_001188"
     CDS             complement(11568..12182)
                     /locus_tag="VWX64_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU9190661.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(12917..13186)
                     /gene="rpsO"
                     /locus_tag="VWX64_001189"
     CDS             complement(12917..13186)
                     /gene="rpsO"
                     /locus_tag="VWX64_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU9190662.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            complement(13327..13956)
                     /locus_tag="VWX64_001190"
     CDS             complement(13327..13956)
                     /locus_tag="VWX64_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU9190663.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            14812..14952
                     /locus_tag="VWX64_001191"
     CDS             14812..14952
                     /locus_tag="VWX64_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU9190664.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            14959..15135
                     /locus_tag="VWX64_001192"
     CDS             14959..15135
                     /locus_tag="VWX64_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU9190665.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            15193..17136
                     /gene="thrS"
                     /locus_tag="VWX64_001193"
     CDS             15193..17136
                     /gene="thrS"
                     /locus_tag="VWX64_001193"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU9190666.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAHEIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(17185..18159)
                     /locus_tag="VWX64_001194"
     CDS             complement(17185..18159)
                     /locus_tag="VWX64_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9190667.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(18152..18829)
                     /locus_tag="VWX64_001195"
     CDS             complement(18152..18829)
                     /locus_tag="VWX64_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9190668.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            18985..20058
                     /locus_tag="VWX64_001196"
     CDS             18985..20058
                     /locus_tag="VWX64_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU9190669.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            complement(20149..20451)
                     /locus_tag="VWX64_001197"
     CDS             complement(20149..20451)
                     /locus_tag="VWX64_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190670.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(20520..20957)
                     /locus_tag="VWX64_001198"
     CDS             complement(20520..20957)
                     /locus_tag="VWX64_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU9190671.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            complement(21033..21875)
                     /locus_tag="VWX64_001199"
     CDS             complement(21033..21875)
                     /locus_tag="VWX64_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU9190672.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRHGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDGKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21987..22637
                     /locus_tag="VWX64_001200"
     CDS             21987..22637
                     /locus_tag="VWX64_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU9190673.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNIDIAKQLYVEKIN"
     gene            22814..23491
                     /locus_tag="VWX64_001201"
     CDS             22814..23491
                     /locus_tag="VWX64_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU9190674.1"
                     /translation="MVVGIAIASGYLNSRLDKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKATIITYPVTFLIYTFAIKKWKASQE
                     GSPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIE
                     GNSNKEY"
     gene            23593..24006
                     /locus_tag="VWX64_001202"
     CDS             23593..24006
                     /locus_tag="VWX64_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190675.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFECLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            24080..24441
                     /locus_tag="VWX64_001203"
                     /pseudo
     CDS             24080..24441
                     /locus_tag="VWX64_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014307.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(24480..24923)
                     /locus_tag="VWX64_001204"
     CDS             complement(24480..24923)
                     /locus_tag="VWX64_001204"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU9190676.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDVEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(24953..27175)
                     /locus_tag="VWX64_001205"
     CDS             complement(24953..27175)
                     /locus_tag="VWX64_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU9190677.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVYFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMIELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            28169..28798
                     /locus_tag="VWX64_001206"
     CDS             28169..28798
                     /locus_tag="VWX64_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9190678.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(28921..30813)
                     /gene="pepO"
                     /locus_tag="VWX64_001207"
     CDS             complement(28921..30813)
                     /gene="pepO"
                     /locus_tag="VWX64_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU9190679.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         9217 a         7007 c         5650 g         9138 t
ORIGIN      
        1 aatccgacga taagcataat ttcccttgtg ttcgataaaa atggattgaa tttcagcttt
       61 aagctcttgg tccttatctg gtttatctag ctgtttcaag tgatagtagt aggtcgaacg
      121 agctagttta atggctttta gaagaagatc taacgaaaac tcagtcatta attcttgaac
      181 aatttctgtc tttcttcttt ctctttttcc tccttcaatc ggagttctct taactttttt
      241 aggatggcat tctccgctct caggtactca ttttctgctt gaagacgttc tagttctgtc
      301 ctctcttcag gtctcttttt tggcttacgt cccattttag gtactctccc tcttgttttc
      361 tcaacaatag tatacccgtt tttcctgtat tgtgctagcc agttaagaag tatcgtacga
      421 cttgggagac cgtattcaag agaaactcta tctttagtcc agccttcatg tcagacttta
      481 ttactcattt cttgttttaa atcaggagaa tagtaacgat ttttcccttt tttgacgaac
      541 tctattccgt aacgatcaat caatttaatc atgtacctaa gattagaatt atttatccca
      601 aatttatttg aaagcttctc taagctatat ccttgttttc taagttcata gatctgaact
      661 ttatcatcat aagttaattt cataataaaa acaccccaaa agttagattt tttctgtcta
      721 acttttgggg tgcagttcat catttcaaca tcctatacta tgagtttttt aattttagag
      781 accttctctc tagctttcaa aaaacttaca atatcctaag tcaatctgtg gatgctgtgt
      841 ttattgatta aagaaactat ctagatcagt agcaaagtga ttagcgtact tcgcaaccgt
      901 ttcagggtat actctattgt gtatactatc tactataact ttcgtagata aattattaca
      961 ttctcattat agtttttaaa taaccaatca tctgattagt gtctatcact acatctgcta
     1021 gtctgacaac agctgtatct tcattgtaat tggtttctat agggacttaa cttgagcaac
     1081 gatattctct accgtaaatc cataattatc aatcacagtc tgagctgggg cagacgcacc
     1141 gaagatgtca ataccgatga ccgcgccatc caaaccaaca tacttgtacc aactttgggt
     1201 cgctgccatt tcaatggcca cacgacgacg agtcttagat ggtaaaatgt cttccttgta
     1261 ggtagcatct tgagcatcaa atagttcggt tgagggcata gataccacac gtactttacc
     1321 accttgtaaa accaattcct tagcagcttt gatagctaga ttgacctcag atcctgtagc
     1381 aatgataata gtatcaaatc ccggggtatc atacacgacg taggctcctt tagcgacctt
     1441 accaaagtct gtcccttctt caactaccaa gttttgacgg gttaagacaa tgacagttgg
     1501 agtggtggta ctggtcaagg catgatgcca agtcgcttga gtttcacggg catccgctgg
     1561 acggataaca gtcaagtttg gcattgagcg taaacctgcc aaatgttcaa ctggttcatg
     1621 agttggacca tcttcaccaa cggcaattga atcatgggta aagacataag ttacaggcaa
     1681 ctcctgaatg gctgatagcc gaatagcagc tttgacgtag tcagagaaaa caaagaaggt
     1741 tccgccataa actcgtaaac caccatgaag agccattcca ttgaggattg ttcccatgac
     1801 aaattcacgt accccaaact gaatattgcg gtttaatgga ttatatttat cttgtaagcc
     1861 atctgccttg atgtaggtca tgttggagtg agctaagtct gccgatccac ctaagaaggt
     1921 tggtaaaact gctgctgtat taatagcatc ttgggacgaa ttacgagttg cttgagagaa
     1981 gccattctca tagacaggga agtctttttc agtaatggtt acaggggatt ttccagctac
     2041 aatagcgtca atctcactag caacttcggg ataagcaacc ttgtaatcag acaccaaact
     2101 agcccaagca tcgtatgcct cctgaccacg atccgctaca tttgtcttga aatcagaata
     2161 tacttcctct ggtacttcaa atggatcgta atcccatccc aaaaacttac gagttgctcc
     2221 tgtttcttct gctcctagtg gtgcaccatg aacagcattt gtaccacttt tattgggtga
     2281 gccgtaacca attaccgttt tcacttcaat caaactcggc ttaccagaaa acttggccgt
     2341 ctcaattgct gtagaaattg ctgctaaatc tgttccatct tctaccagaa ctgtatgcca
     2401 accataagca tcgtaacggg cgcgaacatt ttcagagaaa gtatctttgg tctcaccatc
     2461 caagcagata tcgttggagt cgtagaggac gataagctta tctaaagctt gatgacctgc
     2521 ataagaagcc gcctccgcag acactccttc catgaagtca ccgtctccag cgataacata
     2581 agtataatgg tcaaaaatag gaaaaccatc tttgttgtac ttagcagcta aaaaacgctc
     2641 tgcttgggcg aaaccaacgg cagtagaaat cccctgacca agcggaccag atgtcgcatc
     2701 cacaccagac gtatgcgtca cttcaggatg accaggtgtc ttagatcccc attgccggaa
     2761 atttttaatc tcgtccatgg atacatcctt ataccctgtt aaatgcaaga gagcatacag
     2821 tagcattgat ccatgacccg cagacaagat aaagcgatct cggttaatcc agtttggctg
     2881 ctcaggtgta attctaaggt gctttgtaaa taggctataa gccattggcg cagcacccat
     2941 gacgattccc gggtgaccag aattagattt gttaatagca tctacgccaa gaaaacgaat
     3001 ggcgttaact gattgtagtg acatatattc ctcctaacta ataaatttct tctcaaacca
     3061 ttatttgatt ggcattgttt ttccggtcat ttcttcgtaa tctctagaac agatatccca
     3121 ggctttggca atatcgtcat ccaaaccaaa taatccactg cgacctataa cataaatatc
     3181 tggtcctgcc acatcaattt gtttgaaagt cttacgactc gaagaaccat ccatctcaat
     3241 gatgtagtga taaccattct gaactctaag ctgacggagt tcttggattt tatacaaggt
     3301 agactccaaa aagcgttgtc ctgcaaaacc tggatctaca gtcataatag ttgctttgtc
     3361 aagtaaatca atgtagggaa agattgtaga aacaggtgtt tcaggattaa ggacaacacc
     3421 agcctttaga cctgcatcat gaattttatc aatcaaacga aaagcaagac cattcagaac
     3481 ttcagcatga atacaaatat actcacattg taaatcgaga acttgatcta cccaaaaggt
     3541 tgggtctgtg accatcagat gaactgataa aggtgtgtca ctaatttttt gaacttcttg
     3601 aatgaaccaa ggagacaagg taatattggg aacaaaatgg ccatccataa tatcgatatg
     3661 ataagatgct actttatcat tcaaaaaagt aatctgctct ttgaatttgt ccaaatccat
     3721 ggtcatcaaa gatggtgaaa attcaattct tgacatcgtt accctcttac aaaatttcaa
     3781 tatctgacaa atcaatctct tcttcaacag tcataactgg ttctgtatgt tttattggtt
     3841 ttctcaaaat cgcgtagaca agtcctgtga ctacaatgtt ggctaacaaa gcacaaatac
     3901 cagctactgg acgagtcatg gttggtaaca taagcactcc accaaatggc acggcagaat
     3961 cagcacccat tgtcaaagaa acagcaccac caacagcacc accgatacct gttgcaatga
     4021 gacctggaac caagttattc ataacaatcg gaattacacc ttcaacaata ttgacaatcc
     4081 ccataggaac agccgatttc aatgtttcga tttcctcttg agtatagata ttttttttga
     4141 gtaatttcgc gataaaatag gccaatccaa atccaactgg tgtagcagta ttcaccaatt
     4201 gcaaagcagt caatggttct ttcacacctt cagcctgtaa agtcaacaca aacgcataga
     4261 ctgttttatt aagtgggcca ccaaagtcaa cagcactgag aactccaata actgccccca
     4321 tcaaaccatt tgaagcactt cccaagcttt gtaataagct cgtcaaccag ttggtaaagg
     4381 ctgcgatagg cgccccaata atataaatca taatcaaact acttaccaaa gaggctacaa
     4441 aaggaataat caaggttggc attaaacctt taatccagtt tggtactttg acctttttaa
     4501 taatcgcttg aaccaagaaa ccaactatat aacctcccaa gataccaccg ataaaccctg
     4561 aaccaacaga attggcaatt agaccaacaa caaaacctgg tgcaatccct ggcttaccag
     4621 caatcgagta agacaaacct gtagcaataa caactggcaa gagaccaagg gctttaccac
     4681 ccatagttgc taaagcatcc cagatagtga attttcctgc tacaagagcg tcaggaacac
     4741 caccccccat tgctaaacca atggcaacta agaatcctgc accacaaaca attggaatca
     4801 tataggaaat ggctgtcaat aagtgacctt ttaagtttaa gtgtttcaac atatattttc
     4861 tccttaaata ttttcagtta tttcgtaaca atctcaacag ctttagcaat cagtttattg
     4921 ggagatttga ctgccacttc tgttggaacc ttgataatct ttttaccctc aaagcgttcc
     4981 ataccagaaa tcttaacatc aactgctaaa ataactacat ccgctgcatc aatctgctct
     5041 tgactcaatt cattttctac ccctattgtc ccctgagtct caacatgaat cacatgtcca
     5101 gctacctttg cggcattctc taatttttcc tgtgcaatat aagtgtgggc aattcccata
     5161 gtacaagctg caacaccaac aattttcata cggataccct ccaaaatttt ttcttattaa
     5221 caaaaagctg caatcacatc atcagatgtc tgagcccgaa ctaatttggc aacaacttcg
     5281 tcattaccaa gttttcgagc aaagagtgat aaggtcttca aatgctccct agcagcttct
     5341 gtatcatcac caactgcaaa gagtacaatt actttgaccc ctttcccatc aatggtctcc
     5401 caaggaatct cattgtgatt tatagctatg actacccccg ccttctccac agcagaactc
     5461 ttgctatggg gaatagcaat ataattccca ataccggtct gtccttctgc ctctctctga
     5521 taaagacctt cgataaattg gtctctatca gacacataac ccgtctcaac caatagttga
     5581 gctaatgcct caaaaacctc ttctttgctc tgcatctgta aatccgtctg gatcagactc
     5641 acattaagaa tatctttgat ttccatatat tatctcccgt aattcttctt ttgttaactg
     5701 ttttaattga tttatgaatg attcatctgc tagtcttctc atcaatgttt taatacatga
     5761 cttgtcctgt gatactgcaa tggccaaacc gataataagg tcaacacact ggatatcctt
     5821 cgaccattct ctgataggtg gttttaatct agtaatcact aagacatgat gttgaaagtt
     5881 tccttcacaa tgtggtagaa gaacaccttt agcaacctct atacttccct gtctctcacg
     5941 gtaatataga agctcttcta ttttttctgt atcttcagaa acaagaaggc tgatttgatt
     6001 tgctaattct ttgtaggctt cttgacgatt ttgaacagat atatccataa ggacaagcga
     6061 aagattattc atagtttatc tcctgaattt ttgcttgaag acgttgttta tcaccctcgg
     6121 ttagaaaagc actaactagg acaaacggga cacttgctgg ttcctgcaaa gctaccgtcg
     6181 tcacaatgaa atctaaatct ggatatagat ttatcagctc atctaattga tgataagcaa
     6241 ctacatcaat aatatccaat tcagaaaatt gcttttctaa tcgtgctcgt aaaagctctg
     6301 aagttccgac acctgatgta cacatcacta ctgtttttag aggacgtgct cgcttttctt
     6361 gaaaccgtgc aaaatataag actagaaaac caatctcgtc cagactcaag gacgcaaaac
     6421 caaatactag actcacttct ttagaaatag ttgttaactc tttaaccaga ttaggatagg
     6481 ttaaaagaat ttgtgataaa agactattct taatctgtac tctattatct aatctcctca
     6541 gtaagggact gatatgactc gccaagtcaa caaagtcagg atctgtcgtt tcaatctctc
     6601 tattgtccgt acacatacgg ctaaaatagt aatgagtgac atctaaaact cgctgagaaa
     6661 aaggaagctt cccggaagaa aatggttttt gcaatctcga agatacaacg tattgataaa
     6721 gatagtcaat ctcaactgca tcaaccttca tcctaaaata ttgttcaatt tcttgaataa
     6781 ttttttgaca gacactgtaa attttctcat caacaatagt aggttttgaa ggtgctacaa
     6841 catgaatact agtactacga cgattcctac tgataaaaat atacaggtga gagaaaatat
     6901 ttatattata tggataggga atgtttaccc ccaattctct ctcaagtgta atcagtaatc
     6961 ccaaacaaaa gtgagcaagt tctccgtcaa gaggctgaac cttattctgt gtaatttgct
     7021 ctaaatccaa ctgattaaac attggcagta gatttagaat ggctgaacga atttgagcct
     7081 catccccatc aataaaaagc tttcgttgtc tcatttttaa atctaaccca taaattgcta
     7141 gactctcttg taatatctga cgatctttta gtactactga ctcgcttacg tagaattcct
     7201 ctcctaaatc ataaatagaa tgtggcttag gagcagtcaa caagagacgt tctagtaatt
     7261 tttcacgcct tacttcagga tcaaaagcct ctgtaaaatt cccatcaacg tccacgaggg
     7321 aacttcttgg atttaatttg aaacctctgc ctttttcaga taaaatgaat gcttctaccg
     7381 gacaatcttt gttgattccc ttgacaaggc gataaaccgt tttatcagag caatttaatt
     7441 tttctcccaa tactttagca gatatataat ccttactatc tcgcaaaagg agcaacaacg
     7501 tttccatttg ttcttgtttt ctagacacga tacacctcct ttatgattcc attatatcgc
     7561 tttcaaaaaa taatatactt cgcattttgt cctttgcaat ggacattttt gtttttatca
     7621 aaaatatgat atcaaataga acagaacctc actatgccaa aatcatttta ccttttcttc
     7681 ataacatcta ttttagttga aatatttaag ttgcttttcg tatttgataa gaaataaacc
     7741 aaacgatttt ctaataaata acactatgtt ccatttaaca atagatagca tcttcatttt
     7801 caaactacca acttatccga ccatttgttc tagcaataga agagagttaa aattacttca
     7861 atctgtcgct ttctctttct tacatcaaac ttcaaatagt ctaactacag atatttgaat
     7921 ctattacctc aatccaagca ggcttgagaa tcactcttgg gttcaccgat agatgatcgg
     7981 cacgtaggcc ttgcacatca gatctacgat agatccatcg tataaaaaac tgcaatccac
     8041 agattgcagt ctttctttat tttctagctt gatagcgact agtcaggatg aaaatcactg
     8101 taaagaccaa catcatgaca ccataaacag gcaacgtttg ttctgtcaag gttgaaattt
     8161 caagcagttt ttggattctt gggaagagag ctgtggctag gaagcctcct actgaccaga
     8221 caatcaagag gactcgccat agagtgaatg gcatgcaggc tctaaatacg gataagaaac
     8281 caattgaccc caagagataa tagaggagag ttgagatttc taactcagac caaccttgac
     8341 tcgttccaaa gattttcaca aaaagaacgc taaacacgac catgagggca cttggtaggg
     8401 cacgaagcat ggatcttctg aggaagtttg gctcgacagg tttgatattt cgctcaaaag
     8461 tcaaaacgaa tggtgggaaa ccttccacaa actggtcaat catggtaatc tggattggaa
     8521 tgaaggggaa aatcaagatc cattcagacc gacctagtaa agcactggcg atacagataa
     8581 ctgcgagcaa gaatgagtag atggtcttta tcaagaaaat cggagcgatg tgggcaatgt
     8641 tattgaccac acgacgacct tcaaaaagaa tctcaggaac atcattaaag tctgagttca
     8701 agagaaccag gttggcaatc tgacgggttg ctggatcccc ctccgccatt acgatagaac
     8761 aatccgcctc acgaagagcc aggatatcat taactccatc cccagtcata gctgttgtat
     8821 gacccgcttt tttcagcgtt tggataatga gtttcttttg atgaggggaa acacgtccga
     8881 aaatagctgt ctcctccgcc atggccatca attcctcatc ggtgattttt gagcaatcta
     8941 catagctgtg atagtccgca aaaccagcct tctgggcaat gctggacacc gtaactggat
     9001 tgtcaccaga gataatcttg agtcccacct cctgagaacg gagatagtcc agcgtctctg
     9061 ctgctccctc tcgaatgggg tccaagattt ccagcaaggc tagagcctga atatcagatg
     9121 gtttctgtgg tttgtgatgg tctaatttct cctgactgag agctaagacc aagacacgtg
     9181 atcctctctc caaggcctcc ctggcttctg ggacttcaga atccagcaac atctcaggtg
     9241 cccctaagaa aactgtcccc aagccttcta actccatagc cccccacttg cggtcgctgg
     9301 agaagggaag attggaaatc ataggataag caacatctcc cacaaaacgc tggcgaatgg
     9361 cttgggcagt tggattctta tcctcactat gggccatata gctggtcagg atgctggcaa
     9421 cagcctcttc accgtaagtt tccgtcagtg gaagaacagc ctccacctgc atctttcctt
     9481 gggtgatggt gcccgtcttg tccagacaga gcatatccac gcgcgccaag gtctcaacag
     9541 agtacatctc ctgcaccaag acctttttca agcccaactt aatcactgca gtcaagagcg
     9601 aagtaatggt caaaagggca attcccttag gcaacattcc caaaagagct gtcgacgagt
     9661 ttacaacgga tgacttgaga ggcaggcctt ttaaaagcaa ggcttccagc aagagagcca
     9721 gaccaaaggg aatgataatc ttcccagtaa aaccagccaa cttgtccagc gatttcatga
     9781 tacgggagtt gatgggttta acggtcttag cctcaagcat gagtttggca gcatagttgt
     9841 ctgcaccgac atggtgaact tgagataaaa ctgacccact ggctaggaaa cttcctgaca
     9901 aaagtaagcc gtcaacttcc ttttgcacca aatcactttc tcccgttaac atggcttcat
     9961 tgacttccgc aaagccttcc aaaaccaagg catcactagg aatctgctct cctgcagaca
    10021 aacgaatgac atctcctagc actaattctt caggattaag agcaacttcc tgaccatcac
    10081 ggatggtttt gaccttttcc ttggtcatga gattgagctt gtccaccatg tgtttggctc
    10141 gtagctcggt cacaatccca gaaaaagcgt taaagcagat aacagcaaag aagaccagat
    10201 tgctccaagc ctgcacaaag gcaagggcca aagcaatggc aaagttcaaa gcgttaaaaa
    10261 gggtaaagac atttcgttta acgatttgcc aagtgctggt actggctgat gcggtaaagt
    10321 cattgaccaa accctcagcc tgtctttcct tgatttctct ttgggttaat cccataatct
    10381 tatttttatc cataaattct attatatcat tttttttaac agaattctaa tttcatccca
    10441 aatatgcatc tagtcaaggg aaaagtttgc cagccctcct ttgataaggt ataataataa
    10501 caagaaaaca atcgaaggag atcgcatgtt ttatacttat ttgcgtggat tagttgtatt
    10561 gctcttatgg tccatcaatg gcaatgctca ctatcataat actaataaaa ttcctaatca
    10621 agatgaaaat tatattttag ttgcgcctca ccgtacctgg tgggatcctg tttatatggc
    10681 ctttgcgacc aagccaaaac agttcatctt tatggcaaaa aaagaactct ttaccaaccg
    10741 tatctttggt tggtggattc gtatgtgtgg cgcctttccc atcgaccgtg aaaatcccag
    10801 cgcctcagcc atcaaatatc ctatcaacgt tctcaaaaaa agtgaccgct ctctcatcat
    10861 gtttccaagt ggtagccgcc actcaaacga tgtcaagggg ggcgcagcac tgattgccaa
    10921 aatggccaag gtccgtatca tgccggttac ctacaccggt cccatgactt tgaagggctt
    10981 gattagccgt gaacgtgtcg atatgaactt tggaaatcca atcgatatct cagatatcaa
    11041 gaaaatgaat gatgaaggca ttgaaacagt cgccaatcgt attcaaacag aattccaacg
    11101 tctggacgaa gaaacgaaac aatggcacaa tgataaaaaa ccaaatccac tctggtggtt
    11161 tatccgcatc cctgccctca tccttgctat tatcctcgct atcctaacca tcatctttag
    11221 ctttatcgca agcttcatct ggaacccaga taagaaaaga gaagaacttg catagaagaa
    11281 atgaaccttg gccaaacagc taaggttttc atttatatag tagattggaa ctagaatagt
    11341 acacctctac ttctaaaaca tttttagaaa tcgatttgac tgtcctgatc gattttgtcc
    11401 tattcttatt tcattttact atatttataa gaatccccta atcaaatcaa aagccactct
    11461 acaatagagt aactttaaga ttgtccattt atactcaatg aaaaagccct ctgaaaatca
    11521 gagagctgat ttgagctcag gctaaaatcc tagtgaaaca aaaaaatcta cacgatcaga
    11581 aaagtctcta tcgtgccatt ttcatacatg atgtatagtc caagtagaat gaatactaag
    11641 ggcacaatga ttcgctcgta tttttcaatt gtctcgaata ttaacggaat agaggataac
    11701 accctactaa tctcgcaaaa gataattatg ccgattacaa acacaagcaa ggccacgagg
    11761 gtctgtgacc aatctaacga agcaaaataa ggtatataga tacctaaatt atctccgcca
    11821 gacgcaattg tcagcaatgt aactgtccaa aacagttgat ttgccttgct ttgttctaat
    11881 ctttcaataa tttcttcctc ttcttcttcc gcatcttctc caacaattgc aaagcgaatc
    11941 cctaaataga tagggattaa accaagcaat ccaaccatcc attcttcagg cacgaaatta
    12001 acgacataag cagcaactaa actcgcccct acaagtaagc ctgtgcctag atattgcccc
    12061 gcataaatat gccatttctg tttattctgt gatagctgtg caaataaaat aattaaaata
    12121 attaaataat cgatactggt ggaaatataa acaccaatag cagatatgat tgtctgtccc
    12181 ataaaaaaaa cctcctgtat tagtcagtaa taaatcagca gattttagga gagcacagac
    12241 acattaattt agctatcgct agtgggtaat gtcgaacgta ggaaagcatt ttactcctcc
    12301 tcaaaacgta gttacaaagt aatttctaac tggaattcag tgactacttc catgtaaagt
    12361 ataacatact atactttact ttgtaaagag tgggctcttc tagggggctt gcatacagct
    12421 actcggcttg aaaagccgag taactgcgca cctttatggt gtaattagct gataccgttt
    12481 gaggtttttg tagtctccaa aattgttacc gataaaacct caataaaaaa gccctctgaa
    12541 gtcagagagc tgatttgagc ccgggctaaa atcccagtga aaaagatgaa actccttgtg
    12601 ctcatcgaac actgtgtcat ttccctattt tcatacggat ttttgacgcc cttagcatca
    12661 tgattcttgc tagataaatc gtttatagac taggcgacga ggcgaagatc gtacgaaact
    12721 ttcagtgaaa caaaaaaaat ctccccgaag ggagaaaagc tggtttattt taccttacag
    12781 tgctaggaac cgtaaccaaa gattatactt gagtatatcg aggtaaggtg acaacgcaaa
    12841 aaagctaccc aatttagagt agcttcatta tcaagatatg ctcaattgaa cacggcctaa
    12901 gcacttgtat cttgaattag cgacgaagtc ctagagagtt gatcaactca cggtaacggt
    12961 taacgtcgtt tttacgcaag tatgcaagca agttacgacg gcgaccgatt tttttcatca
    13021 atccacggta agtagcgtgg tcttttttgt gttgtttgat gtgttcgtta aggtggttga
    13081 tttcccaagt aaggacagca acttgaacct ctactgaacc tgtatcacct tcgtgacgtg
    13141 catattgtgc aatgatttca ttttttttct cttttgagat tgccatgatg tttctccttt
    13201 ttatttggct tcatccgagt gacaggttgg catgcctgta accaagaaga agttatttgt
    13261 ctttacgaca atccctattt taccaagatt taaattttct gtcaaacatt aatactctca
    13321 tagttattat ttttcaagta aagagatacg ttcttttata tgatgacctt tttcaagttc
    13381 atctaccaat ccaatagcat aatctgcata actaatctgg cttattcctt tttcattagt
    13441 agtaaaaatt tctcctgcta gaatgtagtt tcctgttttt tcaccatcgg gaataaaatc
    13501 tacagcagga ctgacaaaag tccagttgag attatttttt gtacgaagaa gatccaattc
    13561 atccgcttga tcttttgcta gtgacttaaa ttcttcagga aaatcagacg tatctaaaag
    13621 tcgtgtcgtt tttgtttcat ctatataaag acttcctgct ccccctacaa ctagaaaacg
    13681 tgtctgtgtt ccagcaagaa gctgattaaa tagttcgatt gatttgctgt ggagcggtag
    13741 cgtatctggt gtataagcac caaacgctga aataacagca tcaaatccag taagatcatc
    13801 ttttgtcaac tcaaataaat cttttttaat aatagactca gcttgacttt tgttttcaga
    13861 acgaacaata gccgttactt catgtcctcg tttgactgct tcttcaacaa ttgctttccc
    13921 cgcttgtcca tttgctgcaa taactgctag tttcattttt tatacctctc ttgttgtaat
    13981 tattttagtt acaacaattg tgacactttt aataatcaat gtcaatagtc ttgcttaatt
    14041 attatcaaaa tatttctacc aagaaaacta accatgattc tagtgaaaaa aatcttcttt
    14101 gtcaacaaat ttactttctt gttttaaata tgctataata atcatagcaa gagatctaag
    14161 ttgtctgttt ttttaaaacg aggtgattat catgcgtaga ttctattccc atctccccta
    14221 ctatctggtc atattattct tttattggcc actttatgag ttgttcttgc tagttgtttc
    14281 tgaccccctt acactatata aacaatcttc tcttctttac acctctggta atcttgattg
    14341 tatcgttact ctatagctac cgtttccgtt tctcactttg atggttagtt ggtaacggac
    14401 tgctctttta ctttactatc ataacctttg gtgagtttat actaatttac ttgctaatct
    14461 atgaaacagt tgctctggtc ggcatggatt ctggtattag catcaagcat attctacaaa
    14521 aaatgaaaaa caaaaaactt tcacaaaatc cttgaaaaat ctcacaatca tgctataata
    14581 atccatagag acaagtcact tagtcccttt ctactagaga gtgcgtggtt gctggaaacg
    14641 cataggaagt ctaaactgat actactcttg agttttttat gaaaacataa aacggtggcc
    14701 acgttagagc caatcagagg tgtccctctc ttttgaggta cataaatgaa ggtggaacca
    14761 cgttgcgacg tcctttcgag gatgtcgcat ttttttatta ggatactaat tatggagttg
    14821 caagaattag tggagcgcag ttgggcaatc cgacaagctt atcacgaact ggaagttaag
    14881 catcatgatt tcaagtggac ggtagaagaa gacctcttgg ctttatctaa tgatattgga
    14941 aatttccaat gactggtgat gacaaagcaa ggacgctact atgatgaaac accctacaca
    15001 ctggaacaaa aactttcaga aaatatctgg tggctattag aactttctca acgtttggat
    15061 atagacattc tgacggaaat ggaaaacttc ctctctgata aagaaaagca attgaacgtt
    15121 aggactcgga agtagtctgc tgataaaaaa tcaatgctta gaaactatga aataataaaa
    15181 aaggagaaca tcatgattaa cattactttc ccagatggcg ctgttcgtga attcgaatct
    15241 ggcgtaacaa cttttgaaat tgcccaatct atcagcaatt ccctagctaa aaaagccttg
    15301 gctggtaaat tcaacggcaa actcatcgac actactcgcg ctatcactga agatggaagc
    15361 atcgaaattg tgacacctga tcacgaagat gcccttccaa tcttgcgtca ctcagcagct
    15421 cacttgttcg cccaagcagc tcgtcgtctt ttcccagaca ttcacttggg agttggtcca
    15481 gccatcgaag atggtttcta ctacgatact gacaacacag ctggtcaaat ctctaacgaa
    15541 gaccttcctc gtatcgaaga agaaatgcaa aaaatcgtca aagaaaactt cccatctatt
    15601 cgtgaagaag tgactaaaga cgaggcacat gaaatcttca aaaatgaccc ttacaagttg
    15661 gaattgattg aagaacactc agaagacgaa ggcggtttga ctatctatcg tcagggtgaa
    15721 tatgtagacc tctgccgtgg acctcacgtt ccatcaacag gtcgtatcca aatcttccac
    15781 cttctccatg tagctggtgc gtactggcgt ggaaacagcg acaacgctat gatgcaacgt
    15841 atctacggta cagcttggtt tgacaagaaa gacttgaaaa actaccttca aatgcgtgaa
    15901 gaagctaagg aacgtgacca ccgtaaactt ggtaaagagc ttgacctctt tatgatttca
    15961 caagaagtgg gacaaggttt gccattctgg ttaccaaatg gtgcgactat ccgtcgtgaa
    16021 ttggaacgct acatcgtaaa caaagagttg gcttctggct accaacacgt ctacactcca
    16081 ccacttgctt ctgttgagct ttacaagact tctggtcact gggatcatta ccaagaagac
    16141 atgttcccaa ccatggacat gggtgacggg gaagaatttg tccttcgtcc aatgaactgt
    16201 ccgcaccaca tccaagtttt taaacaccat gttcactctt accgtgaatt gccaatccgt
    16261 atcgctgaaa tcggtatgat gcaccgttac gaaaaatctg gtgccctcac tggccttcaa
    16321 cgtgtacgtg aaatgtcact caacgacggt cacctattcg ttactccaga acaaatccaa
    16381 gaagaattcc aacgtgccct tcagttgatt atcgatgttt atgaagactt caacttgact
    16441 gactaccgct tccgcctctc tcttcgtgac cctcaagata ctcataagta ctttgataac
    16501 gatgagatgt gggaaaatgc ccaaaccatg cttcgtgcag ctcttgatga aatgggcgtg
    16561 gactactttg aagccgaagg tgaagcagcc ttctacggac caaaattgga tatccagatt
    16621 aaaactgccc ttggaaaaga agaaaccctt tctactatcc aacttgattt cttgttgcca
    16681 gaacgcttcg acctcaaata catcggagct gatggcgaag atcaccgtcc agtcatgatc
    16741 caccgtgggg ttatctcaac tatggaacgc ttcacagcta tcttgattga gaactacaag
    16801 ggggccttcc caacatggct ggcaccacac caagtaaccc tcatcccagt atctaacgaa
    16861 aaacacgtgg actacgcttg ggaagtggcc aagaaactcc gtgaccgcgg tgtccgtgca
    16921 gacgtagatg agcgcaatga aaaaatgcag ttcaagattc gtgcttcaca aaccagcaag
    16981 attccttacc aattaattgt tggagacaaa gaaatggaag acgaaacagt caacgttcgt
    17041 cgctacggcc aaaaagaaac acaaactgtc tcagttgata attttgttca agctatccta
    17101 gctgatatcg ccaacaaatc acgcgttgag aaataagagt ctagcataaa agcctccaat
    17161 ctggaggctt tttctcatct atttttactc aaggactaag ttcacttgag caaactgaat
    17221 ccgcactgtc gttccttttc cgacctcaga ctcgatacga atctggtgcc ccagttcttc
    17281 agaaattttc ttagatagat aaaggccaag tccagaggac tgctgggtca aacggccatt
    17341 gtatcctgaa aagccacgtt caaatactcg gaggacatca ctgtttttta tcccgattcc
    17401 cgtatctttg atacaaagct cttggtcatc catataaatc tccagaccac cttccttggt
    17461 gtacttgaga ctgtttgaga tgatttgctc aataaccact agcagccact ttttatccgt
    17521 cacgatttct ttatcaaggt catgtagatt gacatttaag cctttttgaa taaagaaaag
    17581 agcatattta cgaattattt ccttgaccaa gtcctcaatt tgaacctgct ttaagagcaa
    17641 atcatcatgg aaactttcta aacgcaggta ctgtaaaact aggttggtat aggagtcgat
    17701 tttgaaaatt tcctgttcta gctgctgctt cagttggcgg tcgaccactt ctgcaactaa
    17761 gagttgactg gctgcaatgg gggtctttat ctgatggacc cacaaggtat agtaatccag
    17821 caaatccgtc agttttcttt ctgcttttga cctctgctga tagagttcca tctcacgcgc
    17881 ttctaatttt tctgctaaag ctatttccaa aggagacttg gcttccctct ctccatagag
    17941 aagttcctgg cgatagacct gcgtttccac caatatgtcc caagtgaaaa ataagatggt
    18001 tacaaagcaa cacaagaaga aaaagtagag gaagtaaatt cctagactgg caaataaaaa
    18061 ctgaaagagt aagacaagaa atgccaaaga aagcagatag ataaaaagac gactacggga
    18121 gcgcagatag gctagaaaaa attgtttcca atcaagcatg cttcaatccg taccctattc
    18181 ctttcttggt ctcgataaat cctaccaatc cctgctcctc caacttttta cgcaaacgag
    18241 ccacattgac agagagggta ttatcatcaa tgaaaaagtc actgttccaa agttcccgca
    18301 tcaggtcgtc acgtgctacg atgttgcctg catgctcaaa taacacgcgt aaaatctgga
    18361 attcattctt ggtcaaattc aagacttgcc cttgataatg taaatccatg gatttggtat
    18421 tgaggataac accagcatat tccagcaaac tctcatcacg cccaaactca taggaacgac
    18481 gcaacaagcc ctgaacctta gctaaaagaa cctgctggtc aaaaggcttg gtcacaaagt
    18541 catccgcccc catattgatt gccatgacaa tatccatagc ctggtctctc gaagaaagaa
    18601 acatgatagg taccttggaa atcttgcgga tttcctgaca ccagtgataa ccattaaaca
    18661 agggcaaacc aatatccatg aggaccagat gaggttccga ctgaacaaat agactcaaaa
    18721 cttccataaa gtcttctacc aggaccactt caaatcccca ttcagagagc attttcccaa
    18781 tctgttgacg aatgacctga tcatcttcta ttaataaaat cttgtgcatg cgcttctcct
    18841 tttccattat tataacagat ttttccatgc tagatggtct gaaactgaat ttgaaatagc
    18901 ctgtttttag ccagtacaaa caggctatgc tactagctaa tttgagggaa atttgctaag
    18961 ataaataaaa agaaaggagc tcttatggcc aatatttttg actatctgaa agatgtcgca
    19021 tatgattctt attacgacct tcccttgaat gagttagaca ttctaacctt aatagaaatc
    19081 acctacctct cctttgataa tctggtctcc acacttcctc aacgtctttt agatctagca
    19141 cctcaggttc caagagatcc caccatgctt actagcaaaa atcgccttca attattagat
    19201 gaattggctc aacacaagcg cttcaaaaat tgcaaactct cccattttat caacgacatc
    19261 gaccctgaac tgcaaaagca atttgcggct atgacttatc gtgtcagcct cgatacctat
    19321 ctgattgtct ttcgtgggac agatgacagt atcattggct ggaaggaaga tttccacctg
    19381 acctatatga aggaaattcc tgctcaaaag cacgcccttc gctatttaaa gaactttttt
    19441 gcccatcatc ctaagcaaaa ggttattcta gctgggcatt ccaagggagg aaatctcgct
    19501 atctatgctg ctagccaaat tgagcaaagt ttgcaaaatc agatcacagc agtttataca
    19561 tttgatgcac ctggtctcca tcaagaattg acacagactg cgggttatca aaggataatg
    19621 gatagaagca agatattcat tccacaaggt tccattatcg gtatgatgct ggaaattcct
    19681 gctcaccaaa tcatcgttca gagtactgcc ctgggtggca tcgcccagca cgataccttt
    19741 agttggcaga ttgaggacaa gcacttcgtc caactggata agaccaacag tgatagccag
    19801 caagtagaca caacctttaa agaatgggtg gccacagtcc ctgacgaaga acttcagctc
    19861 tacttcgacc tcttctttgg cactattctt gatgctggta ttagctctat caatgacttg
    19921 gcttccttaa aggcgcttga atacattcat catctctttg tccaagctca atccctcact
    19981 ccagaagaaa gagaaacctt gggtcgcctt acccagttat tgattgatac tcgttaccag
    20041 gcatggaaaa atagataata ctcttgaaaa ttaaatgtat acaaaacaaa agacctagaa
    20101 tacatacttt catgtgcatt ctaagtcttt ttaaatagaa tctaatagtc aataaaaatc
    20161 aaagagcatt gagagataat ggggcttgga acgtccctct cgcttcaaca aaatgacccc
    20221 attatagatt aaaaagatgc cacttagaaa aagcaaaaaa ggaagtaaga caaaggtaaa
    20281 tacataaaaa gctaactgaa cattctcgta tccattttta taaaaaaggt aggatagata
    20341 aaaataactt gaaatgaggg ataataaaaa taatactgga ttccacaaac ttctattatc
    20401 cttccaaaat gacactataa aggctaatac aatttctata acgagataca tttcttactc
    20461 ctttaatagc tacattttat cataattatc caaagaaaaa aagagggcat ttatccctct
    20521 taatccttca tctgactctc tgcatcggcc acgacttttt ctagactggt ctgaccaagt
    20581 tctgcctcca tagtcaactg aattctctcc aatttttgat ccaaaacatc atgaatatga
    20641 gctcctacag ggcaatttgg attcggattg tcatggaaac tgaagagttg acctgtctta
    20701 ccaagacatt cgaccgcctg ataaacatct aaaagactaa tatccttaag gtccttgaca
    20761 atctctgttc cgcccgttcc acgcgctact gaaatcagct ctgccttctt caactgggac
    20821 aagatctttc tgataatgac aggattgacc ccgacactag cagccagaaa atcactggtc
    20881 accttgcttt ccttcccctc gagggcaatg attatcagca tatgagtcgc aatggtaaat
    20941 ctacttggaa tttgcatcct cttctccttt ttacgaggct accctgcctc tactcttctt
    21001 tttctattat tatacccttt ttagttgtaa tgtcaatcgt taccactttt caaccagtcg
    21061 tctaactccc gatcgcaacc ctctttctga gccaattctc tcaaaaattc ctgatgatga
    21121 gtatggtgga tcccattgac cagactttca tagtaaacct caaaataggg aagtctcagg
    21181 tctttagcca gctgcaattc agctgccaca tcgtagtcta cccgtcggaa gtccatatct
    21241 accaggccct tgccatcaaa ctccaaaatc atatactggg cccgcaagtc cttccgtagc
    21301 tgagcgtcca aaaagaaagg ttggccaatc gaacccggat tgacaatcaa ttgcccacca
    21361 gtcccgtgac gaagcaactg ctggtgaata tgtccataaa cagcaatatc acagggagga
    21421 tgagtcacca agcggtcaaa atcctcttgt ttgccagtat gaatcaactc tcgcccccag
    21481 ttcttatcag gcagatgatg gctaattccc actgtcaaat ccccaaactg acgatgaatt
    21541 tgaagaggtt gattgtggag cacttcaatt tcttctaggg aaatttcctc taaaacatac
    21601 tggcactggc gcaagagata gcgttgacta gggcgagtac tatccaattc cttacggaca
    21661 ccatgccaaa gactgtcttc ccagtttccc aaaactctag ccgtaatcgg tagttgatcc
    21721 aacaagtcca aaatccttct acgtcctgtc cctggcatga gaatatctcc caaaagccag
    21781 tattcatcca ctcctagctg ctgagcatct gccaaaacag cctccaaggc ggtggtattt
    21841 ccatgaatat ctgaaagaag agctattttc gtcatatcca tctcctcgtt ttttctcttg
    21901 caataagtat aacataaaaa gtcacagcta gagaaatcta gctttttttg atatactaga
    21961 taaagatatt agacaagagg aaacgaatga ccccaaacaa agaagactat ctaaaatgta
    22021 tttatgaaat tggcatagac ctgcataaga ttaccaacaa ggaaattgcg gctcgcatgc
    22081 aagtctctcc ccctgccgta actgaaatga tcaaacgaat gaaaagtgaa aatctcatcc
    22141 taaaggacaa ggaatgtggc tatctactga ctgacctcgg tctcaaactg gtctctgagc
    22201 tctatcgtaa gcaccgcttg attgaagttt ttctagttca tcatttagac tatacaagtg
    22261 accagattca cgaggaagct gaggtcttgg aacacactgt ctctgacctg ttcgtggaaa
    22321 gactagataa actgctaggt ttccctaaaa cctgccccca cggaggaact attcctgcca
    22381 agggagaact cctcgttgaa atcaataacc tcccactagc tgatatcaag gaagctggcg
    22441 cctaccgcct gactcgggtg cacgatagtt ttgacattct ccattatctg gacaagcact
    22501 cacttcacat cggtgaccag ctccaagtca agcagtttga tggcttcagc aataccttca
    22561 ctatcctcag taacgacgag gatttacaag tgaatataga cattgcaaaa caactctatg
    22621 tcgagaaaat caactaattt ctcaagtccc ctaccaaccc tgaaagtttt attttcaggg
    22681 ttttatttct atcatttgat tttactttca tttggtggta gagtatttga aaaaaagaaa
    22741 ggtagtttaa cctatgaaaa aatcactaaa aatttttgct acatctaaat gatttgacct
    22801 cttcggggtt gctttggtcg ttgggattgc gattgcatct ggttatctca actcacgcct
    22861 cgataaattt gtagactggg gactatggac agctcttgta ccctttggat tgatttccgt
    22921 aaccaacgtt gggatttcca tgttgtccac tcgtttcacg gggaaattaa gcaaatgggg
    22981 aaattacttt ggtattgtta ataccatttt gtccggtgct attgattata tccttggaaa
    23041 taaggcgacc atcattacct atcccgtcac cttcctcatt tatacctttg ctataaagaa
    23101 atggaaagct tcgcaagaag gcagccccaa ccaaatgagc caaaaacagg taaaattggc
    23161 ggccatcatc atttccatca tcgccttcct ctttgccttt gtaaccaact atatcggata
    23221 tgggggcaag atgaatctcc ttgcctacgt aacaactatt gcctttgcac tgtccctcat
    23281 tgccaatgct ttgaatgcat tgaaactaac aactcagtgg ggcttttggt tgatttacaa
    23341 tttcgttcag ctgacaaaag ctggtattca aggaaacttc gccaatatcg gtaaatacat
    23401 cttttatatc ctcaatgcaa tcggagcttt atttgtctgg aatgatgaag aagttagata
    23461 catagaagga aactcaaata aagaatacta gccaacttaa gagaatctcc cttctgctat
    23521 ttttatcatt ttagttgtaa ctcccattct tttggagtag aatgaagtta gataaaagag
    23581 gaaggtcttg tcatgaaaaa actctataga atccatttta tagcaattgc agttattgat
    23641 ttgctactat ttgcattttt tatcactaga ctcgagacat cttttgagtg cctcttgctc
    23701 tctggtttaa ttttcttcct tgctcaagga ctcctgctat ttctcttggt cgtccgactc
    23761 aaacatcaat tcgctgagat ttatcctcaa atcaataaaa agattcgctt ctactattta
    23821 ggggttctca ccattgattt tctatttttt gttctcttag ccttcattag ttctcagcgt
    23881 ttttcatctc ttatgccaat tatcactgct tgccattcta ctttttatta tatgacagct
    23941 gactacctag gagaaaacta tccagacttt tacgacaaac acatctcttt atgggagtgt
    24001 ctctaaggaa aaggaggttt tagcatgaaa aaaaatcatc ttcatcaaaa ccattcaact
    24061 ccttgtcatt gatggaatca tgctggcatt tttgacattt aaaaaggggg gcttacttgg
    24121 gactggattt tgatttatag cggttggctc attttctttc atcctgtgct attgacctat
    24181 ctttcaaacc aactttgtga ccactttagt caactctatt cccagattag accgagattc
    24241 tggcgttttg ctttacaaat tctcctatgg gatagcctga tgattctctc cttggtgtct
    24301 ttaagtgata ttccactttt ccttcaggga actctcctca tcctaggaca tctcatccct
    24361 tcctatcgca tctgccaaag cctgaaaaga gacttccccc aagcatatca agaaccgatt
    24421 tctttttgga gtattttatg atcgatgaga aagaccaagc cgactgggct tggtctttct
    24481 tatctctttt tagtatctag gataatggta acaggtccgt tattaaccag ctcaacctgc
    24541 atatctgctc caaagatacc tgtctgaacg ggcacttctt gcgctaattt ttgattgaaa
    24601 gcatcataga agtctgatgc catatcaggt ttagctgccc ctgtaaaggc tggacgattg
    24661 cctttcttag tatccgcaaa gagggtaaac tgagaaatag agaggatttc tccttcaata
    24721 tctttgacag acaggttcat cttgccttct acgtctgaaa aaatccgcat attgaccagt
    24781 tttctcacag catagtccaa atcttcctct tggtcctctg gtccaacacc aaccagcaat
    24841 aaaagtccct gattgatttt tccctgaatc tggccttcta tactcacttg ggctttttta
    24901 acccgttgga taatgatttt cataatagcc tttctagtaa gagctaggac aactagccgt
    24961 tggtccgttt gacagagtaa acttctggca cactcttaat tttatcgaca accgtggtca
    25021 gtgtagagag gttggcaata ccgaaggaca catggatatt agcaaacttc atatccttgg
    25081 ttggttgggc attgaccgtt gaaatattct tggttgtatt tgaaagaact tgcagtacat
    25141 cgttcaacag tcctgtacgg ttgagaccgt agatatcgat atgggccata tactccttat
    25201 ttgagctaga gtactggtct tcccattcca catcaaggag acgttgctcg tagttttctt
    25261 gggcacgcag gttcatacag tccacacggt gaatagccac accacgaccc ttggtaatgt
    25321 agccaacaat atcgtcacca ggcacggggt tacaacactt agcaatccgc actaggagac
    25381 cagaagcacc ttcaataacc actcccccct catgcttgac cttgagagtt tctttatttt
    25441 caaccttgac ctcgccacct ttgacaagct cctctgcctc agccttggcc ttggcacgct
    25501 cttcctcacg gcgttctttt tcagtcagac ggttaaagac ggtaatcgca ccgatttccc
    25561 caaaaccaat ggccgcaaag agggagtctt ctgtcttgta actggtcttt tgcagaactt
    25621 gatccatgtg gcgcttgtcc ataaatttat ttgccacata gccattttct tggaactgag
    25681 ccatcagcat ctcacgaccc ttgttgacag acaattcctt atcttggttt ttaaagaact
    25741 ggcgaatctt attgcgcgcc ttgctagtct tgaccatatt gagccagtca cggctaggtc
    25801 caaaggagtt cgggttggcg ataatttcaa cctgatcccc tgtctttaac ttggttgtca
    25861 gtggaaccat gcggccattg accttggcac cagttgcttt ttcaccgacc ttggtatgga
    25921 tttcgtaggc aaaatcaatc ggtcctgaat ctttgggaag agaacggaca gctccatctg
    25981 gggtaaaaac gtaaatctcc tcagccagat agttttcctt aacagagtcc acaaattcct
    26041 tagcatcatc agcctggtct tggagctcta tcatctcctt gatccagttc attccaatag
    26101 ctgattcctt gctgttaact tgccccttta tacctttctt ataagcccag tgagccgcaa
    26161 ccccgtactc agccacctcg tgcatttcct tggttcgaat ctggaattca atcggccctt
    26221 ttggtccata aacagtcgta tggatagact gataaccatt ggccttgcgg ttggcgatat
    26281 agtctttgaa gcgacctggc atcggtttcc aaaattcatg cacgtaacca agcatggcat
    26341 aaacatcact ttgggtatct aaaatacaac gaatagcaat cagatcatag atttcctcaa
    26401 accgttttct cttgtcctgc attttgcgga aaattgagta aatatgcttg ggacgaccat
    26461 aaatcttccc tttcaagtga cgttctgtcg tatactcctc taattttgtg actacctcat
    26521 ccaccaaggc ctcacgctcc ctgcgctttt ccttcatcat atgggtaatc ttgtaaaact
    26581 ccgttggatt gagataacgg aaagacaagt cttctaattc ccatttgaca ctggaaatcc
    26641 ccaaacgatg ggcaagcggg gcatagattt ccatggtttc tttggaaata cgctcctgct
    26701 tgtcttttcg aagatgtttc agggtccgca tattgtgcaa gcggtcagac agtttgacca
    26761 aaataacgcg gatgtcctca gacatggcca tgagcatctt gcgatgattt tccgctaatt
    26821 gctcctcgat cgatttgtac tcgaccttgc caagcttggt aactccgtca acaatcatcc
    26881 gcacatcagg accaaactct ctttccaaat cgtccaaggt cgcatctgta tcttccacca
    26941 catcatgcaa gaatccacaa gctactgtta cagcatccag ctttagctta gctaaaatac
    27001 ctgccacttg gatagggtga atgatataag gctcgcctga tttgcgatat tgaccactgt
    27061 ggcattcaac agcatagacc aaggccttat ggacaaaata aacatcctct tccgttaaat
    27121 attctttggt taaagcgaca acttcttcgc ctgttaaatt cacttctttc ggcatctcta
    27181 ctctccaatt cttcctacca ttttatcact tttttaagaa tatgaaaact agattggaac
    27241 agaataagaa aaaaataatt caaaattgct tgataattct gaattattgg cccataatat
    27301 actacgaagt tagattttaa acttaggtga tagaaggaga gatagaagaa cggaaaccat
    27361 attgtaaccc aaagactttc tgatttcccc aattccattg aagatacgaa agataaacgg
    27421 tggaactcgt atcacataca ctggtacctt gactggattt tggaattaat actcaatgaa
    27481 aatcaaagag caaactagga aactagccgc aggttgctca aagcactgct ttgaggttgt
    27541 agataagact gacaaagtca gtcacatata tacggcaagg cgacgttgac gcggtttgaa
    27601 gagatttttg aagagtataa aaatcctcaa gatactttct tctatccttt agtttataag
    27661 gagaatacct atgaaaaaaa ctgctatttc tatctttgct ctcctaatgt taggagtttg
    27721 ctgcctgttc ctattcagcc agcaaagcta taaaaaactc gttcaatact atgctaacga
    27781 ccagaacctg cccagtagga taacttatag tgaatatagc gacaaatgag aagccaacta
    27841 cggtagcact ctaaacatca cgtctatcaa acaagctaat gacggagttt atgcaaccta
    27901 tgaagggcaa ttgacacctt tccaatattg ataaattgat aaccagcctg tcttcatcta
    27961 gtcatgctgg tttttaagtt cattttaaat ccttacctat tctccctaac tgtgctatac
    28021 ttaatttata ctcaatgaaa atcaaagagc aaactagaaa gctagccgca ggctgttcaa
    28081 agcactgctt tgaggttgca gataaagttg acgcggtttg aagagatttt cgaagagtat
    28141 tagtacattc tttgagattg gagctagtat gaaaatccat aaaaccgtga atcctgttgc
    28201 ctatgaaaat acctattatc tagaaggcga aaagcacctc atcgtcgtcg atcctggtag
    28261 tcattgggaa gccattcgtc agacaatcga gaagatcaac aaaccgatct gtgctattct
    28321 cttgacccac gcccattatg accatatcat gagtctggac ttggttcgcg agacgtttgg
    28381 caatcctcct gtctatatcg cagagagcga agccagctgg ctctacactc ctgtcgataa
    28441 tctctccggt ctccctcgcc acgatgatat ggcagatgtg gtcacaaaac ctgcagaaca
    28501 cacctttgtc tttcacgaag aataccaact agaggaattt cgttttaagg ttctaccgac
    28561 cccagggcac tctatcggtg gtgtttccct agtctttcct gatgctcacc tagtcttgac
    28621 gggagatgct ctattccgcg aaactatcgg acggaccgac cttccgactg gtagcatgga
    28681 gcaactcctt catagtatcc agacccaact cttcacccta ccaaactacg atgtctatcc
    28741 aggacatggt ccagctacta ctatcgctca cgaaaaggcc ttcaatccct ttttctagca
    28801 agatgatgac aatcgaaatt taagtaaact atccagcaaa tctttctatt acaaaaggca
    28861 tcctatcaag gttttcacac gtgattggat gccttttttc tgatgactag attttttgta
    28921 ttaccaaata atcacgcgct cctctggtga acgccacatt ccgtctcctt ctttgacatc
    28981 ataggttgta aagaaatcgt cgaagtttgg tacttgcaca ttgacacgga gtttggctgg
    29041 tgcgtgcaca tcgacgctag ccaaaagttt cataaattct ggtcgacctt tcatgcgcca
    29101 gatgcgaccg aagttgtaga agaactcttc tgctgagaag tctgcttctc tcttagctgc
    29161 ttcaagcgct gctgcgattc ctcccaagtc agccacgttt tctgatacag tcaatttacc
    29221 gttaatggtt gctccataag aatcctgtcc atcaaattgg tcaatgactt tttgtgtttt
    29281 ctccttgaag gcagcatagt cgctctctgt ccaccaatcc ttgaggctac cattttcgtc
    29341 aaaggaagcc ccgttagtat caaaggcgtg ggaaatttca tgggcaatca ctgccccaat
    29401 accaccgtag ttagcagaag atgactgatg caagtcatag aaaggcgcct gtaaaatggc
    29461 cgctggaaag acaatcaggt tcttctgagg attgtagtag gcattgacca tatgagcagg
    29521 catgccccat tccttataat ctacaggctg gttccactta ctccaactgt gcttgatttc
    29581 cacacgcgca aaggctagag cattctcaaa aagactggca gtttcattca ctaccttatc
    29641 cttgtaacgt gcaggcaatt cttctggata gccaatataa ggtttgatca cattgagctt
    29701 cacgatagcc tgtttacagg tttctggagt gagccagtca ttcttaagca gacgctcctt
    29761 ataaacatca atcatggttg ccactttttt ctccacatcc gccttggctt ctggagagaa
    29821 cttctcacgg gcgtaccaaa gacccagggc ttgcttgaaa ggttcttgtg ctagatgata
    29881 agctgctttg accttatctt ttgcctctgg aactccagaa agggcacggc tgtaggcacc
    29941 agacaaaaca cggatatcct ctgttaaata gctggttgaa agattgacaa cactcaaaat
    30001 caaggttgct ttaaggagag accaggcttc ctcactgtag aattgctctg ctgcttgcca
    30061 gaaacgttcc tcgtctacaa taaccttgtc tggtaattgc ccaataactg ctttgaagaa
    30121 gtcatccaaa ggtagggcag gcgcgaattt cttgaaatct tcgtaagaat atggatgata
    30181 gagtttagca tattctgaac tttcttcatt agagagcacc actgtcgcaa ctcggcggtc
    30241 caattcaagt cttttttcta gcaagtcttc aatttcttca tcagagaaat cataagcctt
    30301 gaggagattt gcgctgcttt ctttccaaag agtcaagagc tcttcgcgct gaggatgttc
    30361 ttctgcatag taggtcgtat ctggcaagat tgtgcttgga gcgctagccc atagaacatt
    30421 gattctagca tccataaagt ctggcgatac accaaaagga aggaagtttg gttttcctgc
    30481 aagctcaaac tctgctagtt tagctgtaaa atccgcaaaa gtctccaatt cttggaattc
    30541 tttaaggagt ggtaagacag gtgtgatacc gtcagcttct ctcttgtcaa aatcacgaac
    30601 taggcggtgg tatttgacaa agttttccaa gatagcatcc tcaggcactt cttcacctgc
    30661 taaccacttg tctgttgtcg ccagcatcag gtcttcaatt tcctggtcta aatcaacaaa
    30721 acctcctgtt tgagacttat ctgctgggat ttcagctgtc tgttgccatt ctccattgat
    30781 agcatcataa aaatcatctt gataacgtgt catcttgttc tcgctttcat ttgtatttgc
    30841 atttatctta acaaaaatca ctagggaatg caattaataa ccatttaact attatttttt
    30901 agctattata aaaaatcttt ccatgataaa acgcataatt ccaagttttt tacacttgat
    30961 actatgcgtt ttataattta gaaatttatc ctgaaagtta tctttagaat ct
//
LOCUS       DAVKBC010000023        29926 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVKBC010000023 DAVKBC010000000
VERSION     DAVKBC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.023"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            167..823
                     /locus_tag="VWX64_001208"
     CDS             167..823
                     /locus_tag="VWX64_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU9190680.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            813..1136
                     /locus_tag="VWX64_001209"
     CDS             813..1136
                     /locus_tag="VWX64_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU9190681.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1240..2070
                     /locus_tag="VWX64_001210"
     CDS             1240..2070
                     /locus_tag="VWX64_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9190682.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2224..3078
                     /locus_tag="VWX64_001211"
     CDS             2224..3078
                     /locus_tag="VWX64_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9190683.1"
                     /translation="MKIKKWLGLVALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3178..4551
                     /locus_tag="VWX64_001212"
     CDS             3178..4551
                     /locus_tag="VWX64_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU9190684.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4544..5605
                     /locus_tag="VWX64_001213"
     CDS             4544..5605
                     /locus_tag="VWX64_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU9190685.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5607..6299
                     /locus_tag="VWX64_001214"
     CDS             5607..6299
                     /locus_tag="VWX64_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190686.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6329..6898)
                     /locus_tag="VWX64_001215"
     CDS             complement(6329..6898)
                     /locus_tag="VWX64_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9190687.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLAYEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7033..7647
                     /locus_tag="VWX64_001216"
     CDS             7033..7647
                     /locus_tag="VWX64_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9190688.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7649..9295
                     /locus_tag="VWX64_001217"
     CDS             7649..9295
                     /locus_tag="VWX64_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9190689.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYYAIDNTRGHTPMAVTVTSPFDTEIFHMGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9307..10593
                     /locus_tag="VWX64_001218"
     CDS             9307..10593
                     /locus_tag="VWX64_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9190690.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10645..11178
                     /locus_tag="VWX64_001219"
     CDS             10645..11178
                     /locus_tag="VWX64_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190691.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11256..11726
                     /gene="nrdI"
                     /locus_tag="VWX64_001220"
     CDS             11256..11726
                     /gene="nrdI"
                     /locus_tag="VWX64_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU9190692.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12019..13281)
                     /locus_tag="VWX64_001221"
     CDS             complement(12019..13281)
                     /locus_tag="VWX64_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU9190693.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13591..14049)
                     /locus_tag="VWX64_001222"
     CDS             complement(13591..14049)
                     /locus_tag="VWX64_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU9190694.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14046..14486)
                     /locus_tag="VWX64_001223"
     CDS             complement(14046..14486)
                     /locus_tag="VWX64_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9190695.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14842..16791
                     /gene="mutL"
                     /locus_tag="VWX64_001224"
     CDS             14842..16791
                     /gene="mutL"
                     /locus_tag="VWX64_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU9190696.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17116..17583)
                     /locus_tag="VWX64_001225"
     CDS             complement(17116..17583)
                     /locus_tag="VWX64_001225"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU9190697.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17584..18789)
                     /locus_tag="VWX64_001226"
     CDS             complement(17584..18789)
                     /locus_tag="VWX64_001226"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU9190698.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18809..19444)
                     /gene="ribE"
                     /locus_tag="VWX64_001227"
     CDS             complement(18809..19444)
                     /gene="ribE"
                     /locus_tag="VWX64_001227"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU9190699.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19429..20529)
                     /gene="ribD"
                     /locus_tag="VWX64_001228"
     CDS             complement(19429..20529)
                     /gene="ribD"
                     /locus_tag="VWX64_001228"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU9190700.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20663..20777)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            20934..21527
                     /gene="ruvA"
                     /locus_tag="VWX64_001229"
     CDS             20934..21527
                     /gene="ruvA"
                     /locus_tag="VWX64_001229"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU9190701.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21537..22100
                     /locus_tag="VWX64_001230"
     CDS             21537..22100
                     /locus_tag="VWX64_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU9190702.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22097..22774
                     /locus_tag="VWX64_001231"
     CDS             22097..22774
                     /locus_tag="VWX64_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9190703.1"
                     /translation="MMSNKNKGILIFVILYTVLFVFDGVKLLASLMPFAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(22929..23960)
                     /locus_tag="VWX64_001232"
     CDS             complement(22929..23960)
                     /locus_tag="VWX64_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU9190704.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKHLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(24215..24898)
                     /locus_tag="VWX64_001233"
     CDS             complement(24215..24898)
                     /locus_tag="VWX64_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU9190705.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24910..25854)
                     /locus_tag="VWX64_001234"
     CDS             complement(24910..25854)
                     /locus_tag="VWX64_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU9190706.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            25986..28817
                     /gene="uvrA"
                     /locus_tag="VWX64_001235"
     CDS             25986..28817
                     /gene="uvrA"
                     /locus_tag="VWX64_001235"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU9190707.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHG"
     gene            28810..29871
                     /locus_tag="VWX64_001236"
     CDS             28810..29871
                     /locus_tag="VWX64_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9190708.1"
                     /translation="MDKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         8564 a         5799 c         6630 g         8933 t
ORIGIN      
        1 gtgttttgag ctgacttcat cagttctatc tgcaacctca aaacagtgtt ttgagcaacc
       61 tgcggctagt ttcctagttt gctctttgat tttcattgag tattattaag acaatatgag
      121 gagaaagatg aaagaaaaag gattttagga gggggcgcag gcagccatgc caacggctct
      181 tggctatgtc agtatcggcc tggcctgtgg gactatcggt gcgccctatg tgacacctgt
      241 tgagatgggc ttgatgagtc tctttgttta tgctgggagt gcccagtttg ccatgttggc
      301 actgattgtg gttcaagctc ctgtggcagc tattgctatg acggtttttc taatcaactt
      361 gcgtctcttt ttgttgagtt tacacgcatc gacttatttc cgtcatacca gtctttggta
      421 caatatcggt atgtctagta tcttgacaga tgagacctat ggcgttttga tgggtgaatt
      481 ggcccataca gacaaggtaa atcctatgtg gatgcacgga aacaatctta acagctatgt
      541 ggcttggttt gtggggacag tagtcggaac ggctctgggt ggcctgctac caaatccaga
      601 aatctttggc ttggattttg ccctggttgg gatgtttatt ggtatttttg cttcgcaatt
      661 tcagattatg caaagacgga ttcctgtccg caatctgctc attatcctag cagttgttgc
      721 ggtgtccttc tttttgctct tgacagtggt gtctcagtca ctagctgttc tgtttgcgac
      781 gctacttggt tgtagcatgg gggtggtttt agatggtcag taagtatctt ttattagcag
      841 ttattttctc tggcttggtg acttggattc tccgtatgat tcccttcatc ttagtcaagt
      901 ataagggctt gcctgcaatc gttgagcgtt ttttgaagtt cttgcccgtt tccattatct
      961 ttgccttgat tctttcaagc gtagtgacag gtaaggttgg gagccttcct caaattaaat
     1021 ggctagactt cttagccgtc tttccaacag cttgggtagc ctttcgctac cgcaatctag
     1081 tcggaacagt tctctttgga gtggtcttga ttgccatctt gcgtttggtc ttttaaatta
     1141 cccataaaaa aaacttatca cagagataga tatcatataa tggcgtaaat gctctttttc
     1201 tgttaagatt ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac
     1261 tcatctcttg ctgccctagg acttgttgct gcaggtgtgc ttgcggcttg ctcagggggt
     1321 gctaagaaag aaggagaagc agctagcaag aaagaaatca tcgttgcaac caatggatca
     1381 ccaaggccat ttatctatga agaaaatggc gaattgactg gttacgagat tgaagtcgtt
     1441 cgcgctatct ttaaagattc tgacaaatat gatgtcaagt ttgaaaagac agaatggtca
     1501 ggtgtctttg ctggtcttga cgctgaccgt tacaatatgg ctgtcaacaa tcttagctac
     1561 actaaagaac gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc
     1621 cttgtcgtga agaaagatga ctctagtatc aagtctctcg atgatatcgg tggaaaatcg
     1681 acggaagtcg ttcaagccac tacatcagct aagcagttag aagcatacaa cgctgaacac
     1741 acggacaacc caactatcct taactatact aaggcagatt tccaacaaat catggtacgt
     1801 ttgagcgatg gacaatttga ctataagatt tttgataaaa tcggtgttga aacagttatc
     1861 aagaaccaag gtttggacaa cttgaaagtt atcgaacttc caagcgacca acaaccgtac
     1921 gtttacccac ttcttgctca aggtcaagat gagttgaaat catttgtaga caaacgcatt
     1981 aaagaactct acaaagacgg aacgcttgaa aaattgtcta aacaattctt cggagatact
     2041 tatctaccag cagaggctga tattaaataa tttcttgaaa tcatccattc tgagtaagat
     2101 gggtgatttc tcagttttta gggatatagt tttaaactat atatctgatt atctaataac
     2161 aatttgtgaa atcaaacaaa ttgtgagata ctagtacggt attattttta aggagaaaga
     2221 atcatgaaaa tcaaaaaatg gcttggccta gtagcccttg ctacagtcgc aggtttggct
     2281 cttgcagctt gcggaaactc agaaaagaaa gcagacaatg caacaactat caaaatcgca
     2341 actgttaacc gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga attggttaaa
     2401 aaagacggaa ttaccttgga atttacagag ttcacagact actcacaacc aaacaaagca
     2461 actgctgatg gcgaagtaga tttgaacgct ttccaacact ataacttctt gaacaactgg
     2521 aacaaagaaa acggaaaaga ccttgtagcg attgcagata cttacatctc tccaatccgc
     2581 ctttactcag gtttgaatgg aagtgccaac aagtacacta aagtagaaga catcccagca
     2641 aacggagaaa tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt
     2701 caatcagctg gcttgattaa attggatgtt tctggaactg ctcttgcaac agttgccaac
     2761 atcaaagaaa atccaaagaa cttgaaaatc actgaattgg acgctagcca aacagctcgt
     2821 tcattgtcat cagttgacgc tgccgttgta aacaatacct tcgttacaga agcaaaattg
     2881 gactacaaga aagcactttt caaagaacaa gctgatgaaa actcaaaaca atggtacaac
     2941 atcattgttg cgaaaaaaga ttgggaaaca tcacctaagg ctgatgctat caagaaagta
     3001 atcgcagctt accacacaga tgacgtgaaa aaagttatcg aagaatcatc agacggtttg
     3061 gatcaaccag tttggtaata agaaacaggg aggtgggaga gagaattcca cctcttgctt
     3121 ttgtatagag cacggagtgt aaagaagact attcgttcat agaaaggtag agagaatatg
     3181 gtttttccta gcgaacaaga acagattgaa aaatttgaaa aggatcatgt agcccagcat
     3241 tattttgagg ttttgcgtac cttgatttct aagaaatcag tctttgccca gcaggttgga
     3301 ctcaaggaag tcgcaaatta tctgggtgag attttcaagc gtgttggagc tgaagtggag
     3361 attgatgaga gctatacagc gccctttgtc atggcacatt tcaagagttc gcgtccagat
     3421 gccaagacct tgattttcta taaccactat gacactgtgc cagcggatgg ggatcaggtc
     3481 tggacagagg atccttttac gctttcggtc cgcaatggct tcatgtatgg gcgtggagtt
     3541 gatgacgaca agggtcatat cacagctcgc ttgagtgctt tgagaaaata tatgcagcac
     3601 catgatgatt tacctgtcaa tatcagcttt atcatggagg gagcggagga atcggcttca
     3661 acagacctag ataagtattt ggaaaagcat gcagacaaac tccgtggggc ggatttgttg
     3721 gtctgggaac aagggaccaa aaatgccttg gaacagctgg aaatttctgg tggcaataag
     3781 gggattgtga cctttgatgc caaggtaaaa agcgctgatg tggatatcca ctcgagttat
     3841 ggtggtgttg tggaatcagc tccttggtat ctcctccaag ccttacagtc tcttcgtgct
     3901 gcggatggcc gtatcttggt tgaaggcttg tacgaagaag tacaagagcc caatgaacga
     3961 gaaatggcct tgctagaaac ttatggtcaa cgaaacccag aggaagttag tcggatttat
     4021 ggattggagt tgcctctctt acaggaggag cggatggcct ttctaaaacg tttctttttc
     4081 gagccagcgc ttaatatcga aggaatccag tctggttatc aaggtcaggg tgttaagact
     4141 attttacctg cagaagccag tgccaagcta gaggttcgtc tggttccggg cctagaaccg
     4201 catgatgttc tggaaaaaat tcggaaacag ctagacaaaa atggctttga taaggtagaa
     4261 ttatactata ccttgggaga gatgagctat cgaagcgata tgagcgcacc agccattctc
     4321 aatgtgatcg agttggccaa gaaattctat ccacagggcg tttcagtctt gccgacgaca
     4381 gcggggacag gacctatgca tacggtcttt gatgccctag aggtaccaat ggttgcattc
     4441 ggtctaggaa atgccaatag ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat
     4501 tattacaccc atatcgaatt agtagaggag ctgattagaa gctatgagta gagatattat
     4561 caagttagat cagatcgatg tgacttttca ccaaaagaag agaaccatca cagcggttaa
     4621 ggatgtgacc attcacatcc aagaagggga tatctacgga atcgttggat attctggagc
     4681 agggaaatca acccttgtac gggtgattaa tctcttgcaa aaaccatctg cagggaaaat
     4741 taccattgac gacgatgtga tttttgatgg taaggtcacc ttgacggcag agcagttgcg
     4801 tcgtaaacgt caagatatcg ggatgatttt ccagcatttt aacctgatga gtcaaaagac
     4861 agcagaggag aatgtagcct ttgcccttaa acactctgga ctcagcaagg aagaaaagaa
     4921 ggctaaagta gctaagttgt tggacttggt tggtttggca gatcgtgctg aaaactaccc
     4981 ttcacaacta tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga
     5041 tccaaaaatc ttgatttcag acgagtcaac ttctgccctt gaccctaaga caaccaagca
     5101 gattttggcc ttgttgcaag atttgaacca aaaattagga ttgacagttg tcttgattac
     5161 gcatgaaatg cagattgtca aagacattgc caaccgtgtg gcggttatgc aggatgggca
     5221 tttgattgaa gagggaagtg tccttgaaat cttctcaaac cctaaacaac ctttgactca
     5281 agactttatc tcaacagcca caggtattga cgaagccatg gtcaaaatcg agaagcaaga
     5341 aatcgtggaa cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg ctggagcttc
     5401 aacagacgag ccacttttga atgaattgta caagcattac caagtaatgg ctaatattct
     5461 ctatgggaat atcgaaattc tcgatggtac tcctgttgga gaattggtgg tggtcttgtc
     5521 aggtgaaaaa gcagcgttgg caggtgccca agaagccatt cgtcaagcag gtgtacaact
     5581 aaaagtattg aagggagtac agtaagatgg aatcattgat tcaaacctat ttaccaaatg
     5641 tctataaaat gggttgggct ggtcaggcag gctggggaac ggctatctac ttaactcttt
     5701 atatgacagt tctttccttc attatcggag gcttcttggg gctagtggca ggtctctttc
     5761 tcgtcttgac agcgccaggt ggtgtcttgg agaataaagt cgtattctgg attttagaca
     5821 aaattacctc aatttttcgt gcggttccct ttatcatcct cttggcaatc ttgtcaccac
     5881 tttctcactt gattgttaaa acaagtatcg ggccaaatgc agcccttgtc ccactttctt
     5941 ttgcagtctt tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg
     6001 gtgtcattga ggcggctcaa gcgagcggag cgactttctg ggacatcgtg ggtgtttacc
     6061 tatcagaagg tcttccagat ttgatccgtg tgacgactgt gaccttgatt tcccttgttg
     6121 gggaaacagc tatggccggt gcggttggag ctggtggtat cggtaacgta gccatcgctt
     6181 atggatttaa ccgctacaat cacgatgtga ccatcttggc aaccatcatt atcattttga
     6241 ttatctttgc aatccaattc ttgggagatt tcttgactaa gaaattgagc cataaataaa
     6301 aaagagccgt gtggctcttt ttaactgatc agattttctg ggcaaatttt ttactcaagg
     6361 cttgtccaat caaggcaccc actagggctc cgatgacaat acttgcgata aatagaagga
     6421 cagttccagg gtttggagtg accatgatac ggtcgatata ttcttgggat tttcctcttg
     6481 ccagaagagt agccatatag gctttgggcg caatccacat aagcaagatt ggtcctgttg
     6541 tactaaaggc gaaaataatg aaagaaagga agttctttgt tttgtccttg tattttccta
     6601 aatgagctac ttcatatgct aggaggccac agataattcc aggaaggaag gaaccagcac
     6661 cgtgtttagt tcccaagaaa aagaaggcaa tgacaaggcc gatagtggta atggctccaa
     6721 agcgcggaac ttttgcgact aggatcatat agacgctacc gccgacaagg gcagtaaagg
     6781 caggcgcata aaacatgttt ccagtttggt caaagagatt gcccaaaagg acaccaatcc
     6841 ccatgcagag gaagtaaaga actgcaaaaa gcagtgtagt taagatagat tttttcatga
     6901 attgtctcct gataattttt tcacaattct cattgtacca cggtttggtg ggattgtaaa
     6961 tggatactag aagtttttga aaacgcttga aatatgatat aatggtttca tagttatttt
     7021 taggggaata tcatgggtag atttttagac tttgtcttta atcgtttctt tttagggatg
     7081 attgcgacag ccttcttttg gctattaact ttagcaggag ggattatcct tggtctagcg
     7141 ccggctagtg ccaccttgat gagcttatat gcagaacatg gttatagctt tcgggaatac
     7201 agtttgaagg aggcttggtc tctttacaag caaaattttg tctcaagcaa cctgattttc
     7261 tatagctttt taggtgtggg tctagttttg acctatggtt tgtatctctt ggtgcaattg
     7321 cctcatcaga ccattgttca tttgattgcg acccttttga atgtcctagt agttgccctg
     7381 atctttttgg cttatacagt atctttaaaa ttacaagttt attttgcctt gtcctatcga
     7441 aatagtctca aattatcctt gattggcatc tttatgagtc tagcagctgt ggccaaggtt
     7501 ctccttggga ctgtgctact tgtagcaatt ggttactata tgcctgccct gctatttttt
     7561 gtaggaattg ggatgtggca tttctttatc agtgatatgt tggaacctgt ctatgaaatc
     7621 atccatgaaa aattggcgac aaaatagaat gaagcagttt tggctacata cgcttctaag
     7681 aacctatagt tcagtgatga tcattatcat tgcgagtttt gcaatcttac tctcttacgc
     7741 tgactgggat tcacgtgaaa aggaagccca gagagtagcc cagcgtgtaa ctgctagaac
     7801 agtgagtgaa attgaatatt accatagaga gtcaacccag atagctcagg ctttagttga
     7861 aaatcaagct cgtatcgagg gaatctataa atactttagc cttagcatgc cagactattt
     7921 ttactggcaa ttagagcgga aagcttcgcc ttatatatca gtctctctgt atgaaaatgt
     7981 tgatgacctc tatgttcgaa atgattttgt aactggggtg gccattgctt ttcaagatta
     8041 caaggaagtc tatgtttcta ctaaagacaa acgtagtgga gaaaaaatca gggctgagga
     8101 tttcaaacca gcaggaaata gttttgccat tccagtgtca gatccagtgt cagatcaaga
     8161 cttaggagtg atttacatct ccttggatcc tgctgtttta tactatgcca ttgataatac
     8221 tagaggtcat actccgatgg cagtaacagt gacctcacct tttgatacgg agatttttca
     8281 tatgggtgag acagttgata aggagagtga aaattggcta gttggcttaa cttctcatgg
     8341 ttatcaggtt caggtggcag ttcccaaaaa ctttgtttta caaggaacgg tgaccagctc
     8401 tgctttgatt gtgggcttga gccttctctt tattgtcatt ctttatctga ctttgaggca
     8461 gacctttgct aattatcaaa agcaggtagt ggatttggtg gattccatcc aagctattgc
     8521 ccaaggacaa gaaggtcttc gcattgatac gcttgaaaag gatcaggaat tgctcctaat
     8581 cgcggagacg accaatgata tgttggatcg attggaaaag aatatccatg atatttacca
     8641 gttagaactc agtcaaaaag atgccaatat gcgggccttg caggcgcaaa tcaaccctca
     8701 cttcatgtat aatacgctgg agttcttgcg tatgtacgca gtcatgcaga gtcaagatga
     8761 gttggcagat atcatttatg aattcagtag tctcttgcgt aacaatattt ccgacgaaag
     8821 agagaccctc ctcaaacagg aattagaatt ttgccgtaaa tacagctatc tctgcatggt
     8881 tcgctatccc aagtccattg cctatggttt caagatagat ccagagttag agaatatgaa
     8941 gattcccaag tttaccttgc aaccgctggt agaaaactat ttcgcgcatg gtgttgacca
     9001 caggcggaca gataatgtga ttagcatcaa ggctcttaaa caggatgggt ttgtggaaat
     9061 tttggtggtc gataatggta gaggaatgtc ggctgaaaag ttggcaaata tccgagaaaa
     9121 attaagtcag aaatattttg aacaccaagc cagctacagt gatcaaaggc agtctatcgg
     9181 gattgtcaat gtacacgagc gttttgtgct ctattttgga gaccgctatg ccattactat
     9241 agagtctgca gagcaagccg gtgttcagta tcgtattaca attcaagatg agtagaaagg
     9301 gagaaaatgt ataaagtatt attagtagat gatgagtaca tggtgacaga aggtctgaag
     9361 cgtttgattc cctttgataa gtgggatatg gaggtcgtcg caacagccag tcatgccgat
     9421 gaagctctag aatatgttca ggaaaatcct gtcgatgtca tcatttccga tgtcaatatg
     9481 ccagacaaaa cagggcttga tatgattcgg gagatgaaag agatcttacc agatgctgcc
     9541 tatatcctgc tctcaggtta tcaggagttt gattatgtaa aaagagcaat gaaccttagt
     9601 gtggtggact atttggtcaa gcctgttgat aaggtagagc tgggaaatct gttggagaag
     9661 attgcaggtc agctcggcga gagagggaag aaaagtcaga ctcttagtca agaattagac
     9721 gaggctggat ttgttagtta tttaggggat aaggagaatt ggtggatagg tctatccaag
     9781 gaaaaacaag gttccttcac cattccctac tatgtcttgg gccaagactg gcagattttc
     9841 atttctgacc aacccctaga tggtttagtc gttacacctt ttgaagctcc ttatcaagaa
     9901 cactttgaac gctggaagct gaatgctgag aaaaccctct tttacggttc tgtaaatttg
     9961 cagcagtctg agagtctctt tgcctattac gaaccgattt atagggttat tattcaggga
    10021 aatctcaatc aaatcgtaga agagttaaat ctcttggaga aggtagttct tgaaaatacg
    10081 ccgcgtgttc cgattactaa acagcttttt attcagtttg tcatggatgt tttccattta
    10141 tttgaacatc tcaaagctga tgacctgaca gacatcgtca aaaccattca tgctattcaa
    10201 tccttcgatg aattggttcc ttatatcaag gaaactctga gcagcttttt cggtcaatac
    10261 cgtatgaatg aaaatgtggt cagtgtgctg gaagtcattg gtcgtgatta ccaaaaagag
    10321 ctttccctca aggatatcag taaggctctc tttatcaatc ctgtctatct agggcagttg
    10381 attaagcgtg aaaccgattc gacttttgca gagttactaa acaaacaacg tattaaggct
    10441 gcccaacaac ttttgctttc aactagtgac agcatcgaag atatttgtta tgctgttggt
    10501 tacagtaacc ttggatattt ctataaagtt ttccgaaaat tgtgcggaaa atcgccaaaa
    10561 gcctaccgaa aacaggtaga aactatacta taagatttgt attcctttac aaaaggtgct
    10621 ataatattat caggaggtcc tatcatgaaa aagaaaccaa tttatctatg ggtcttgcta
    10681 atcttgtctg cccttatttc agttccgtct ctgtttggaa ttgtgagtcc cttgcctagt
    10741 aaagaagccc ttcgtgctgc tcagaaacaa gttgcagggg tcaatgctca gcaattagaa
    10801 gaccagctta attataccta tagagtagca gaagcatctc attctatttt taatgttgct
    10861 ttgattgtgc tatctactat tttagtggtc gtagcgattg tcttccttgt tcgtaaaaat
    10921 ttgcaatatg caaactatac ttacgttggc tatgttttgt tagctattat tggttcgatt
    10981 tatggctatg ttggtttaca agacgctgtg cagttggttc aagatgagag catgcgtttg
    11041 acagtgagta ttggctcaaa agctgttagc attttctata tcgtcatcaa tgttctcttc
    11101 ctagcccttg tcttctataa gatgtggcga caacagaaag ccttggcaga agaagaggaa
    11161 acagaagagc ttacctaagt attgacaaaa aagaactatc aagatacaat cttggtagtt
    11221 gttttttgat tatagataaa atcatggagg tacatatgaa gacaatttct ttagtttata
    11281 ttagtttgag tggcaacact gaaagttttg tgacgcgctt gaaagactat ctcttgtccc
    11341 agtacaaagg gattgaggtt caaaagattc atatcaagga tttggtcaag gaaggcaaaa
    11401 atttctatga aatggaccat ccctatgtcg cttttttgcc gacctatctc gaaggtggga
    11461 atggcgtgga taacggagat gttgagattt tgacgacacc ggtgggagat tttattgcct
    11521 atggtaacaa tgctagtaag tgttttggtg tggttgggtc aggaaatcgt aactttaata
    11581 accaatactg cctaacagcc aagcaataca gtcaacgctt tggcttccct gtattggctg
    11641 actttgaaat gcgaggcatg ctggaagata tcaaacatgt cgcagctatt atcgcagatt
    11701 tgtatgagtt ggaaaaggag aattaatact caatgaaaat caaagagcaa actaggaagc
    11761 tagtcgcagg ttgctcaaag cacagctttg aggttgcaga tagagctgac gtggtttgaa
    11821 gagattctcg aatagtataa agttcttata agaggtggtt gaagttgttc aactgttttt
    11881 tgagtataaa cagtctttaa gaacgtaaaa aagcataagt tcaggtcttc aaaaccttgt
    11941 tcttatgctt tttatcatag aaatatttgc tgaattttct cttgaaatga aaccttatct
    12001 tcatctcgcg cttgtccctt accctgcttt tccgattgcg agtgcgtaga taaagaagat
    12061 ggcgaagcca aagaggaaaa tcaatcccgc aatggcaagg tgtttgagcc aagaaggaag
    12121 atttttgttt tcacgcgtta ccaaggcgta attcaaaaga gcaaagaaag gtgttgtcag
    12181 gaaagatcca atcatggcaa agcggagcat ggttgaaacc tgaccagcga agaacttgat
    12241 aatgacgata ccgatgatag cagtgatggt catccagatg ttcaaagatt tacgattgtc
    12301 ctctttttga ctgattagca gtcggagaga ttcctgatta acgcgagaat agccatcgat
    12361 aacagttata actgttccaa agatacagag gaaggcaata aaggtaatca agtaacggga
    12421 ccattcgcca agaacagagg catacatgcc cacgaattga gagatgtatt tggctgaagc
    12481 agcttcaacc gcctgccctg taggatattg aatcagtgct cccagtgcca caaagaagac
    12541 ggctaggata gctgttccaa tataaccagt gttaaagtca aacagagcgt cttctgtgtt
    12601 aaagttgacg gtctttctct tttcagctga ccaaagtgaa ttgatggctg aaatttcaat
    12661 aggagccggc atccatccta ggagggagac gatgaagggc agagctgcca tttgccaagg
    12721 tgtcttctcg acaaaatcag aactgtattc tggatgcttg accgccgcaa tgataactgc
    12781 aagaacagtc gcaatggtta aggcagacat aatccatttg accatgccgt ctaaaagttt
    12841 gtagcctcca aagagtagca tagcccaaat gattgcaacg agaatgaggg accactgagt
    12901 aatgctaagt ccaatcattg ggaaggcact ggcgatgata gctgagcaca gaatggcaac
    12961 accagccgtg ttgaccatag ccgaaaagac attgagaata aagaaaatcc agagatagag
    13021 ttttcctttt tcggcataac cttcaaccaa agtctttcca gtatcagctg tgtattcagc
    13081 accaaaacgg aaaaatggat atttaaagac attggctaag atgaccaaga gaagtagaga
    13141 ccaaccgtaa gaaccgccag cttgagttga ggatacaatg tgggaacctc caacagcggc
    13201 agttgccatt aggattccag gtcccattgc ttttagcttg cttgcccagg ttgattgatt
    13261 taaggaaata gcttgcgaca tgataaatac tcctttttga attttcagaa taatctgtat
    13321 attcaatcta tattctacaa aaaattttgg aaaaatgcaa gaatattttg aaaaaagata
    13381 gaaaatttac aaagaaaatc tgaaataact gttatgatat agcagattga aactagaata
    13441 gtacactttt gcttctaaaa cattgttaga aatcgatttg actgtcctga ttgatttatc
    13501 ctgttcttat ttcatttcac tatagtacgg tgcagcagga taaagcaaaa ccgagaagtt
    13561 tctttctcgg ttttgcttat tatgaggttc ctattttcta tgctccaaga gttgattgat
    13621 gtgatctact tttttagcct ctcttttata gagaatagcc cagatgatga gatagacaat
    13681 cgcaaactcg ataatgagct ggaggtagaa aatccagtgg aaggggaacc aaccagcaag
    13741 agttgctagt gggacaaagc cagccagcat aaggaagaaa tgagtcagag tggcacgaag
    13801 catgctccag tcacggctga ataagcggtt gccaaagttg aagagcatac cgatggctgc
    13861 ccagataagt gtgcagtaga gcaagaccag ggcaccgtga acctgatgct gatccatcac
    13921 ttggccgatg agagagtagg gatttagtgg tgcgtaggta tttggtgcat aaatgagtga
    13981 aaagaggatg gagaggatga ggccgataag aacaccggca gctgcatcgt gaaatacttg
    14041 ttttttcata gttctaattt ctccttgatg gtttttagat aacggcgtga agagtaggtg
    14101 aagctttcgt ttttcaagaa aatttctacc agaccgtttg gcgtgagctt gaggtgagag
    14161 atggaatcga tattgatgat ttctgattgg gaaatttgga taaaattggt tggcaagagt
    14221 ttaagaacct gatagagtcg caaatcaatg ctgtaggtct gactcgcggt ttctgctaga
    14281 accttccgat tctcgatata gaagcgctga atcttgccaa tctcaactag atagacctga
    14341 tcatcgattt ttcctttgat tttttctctt tggtccagat tttctgcgaa ctcgatgact
    14401 ttctggactt tttcggtttc ttgaggtgct tggacaatca gcttttcctc ctcgtaagtc
    14461 tcactaatct gtagttctac tttcatagtt ttctctcctt gtttttcata caaaattaat
    14521 ctcacttctt gtacaccttt attaatactc ttcaaaaatc tcttcaaacc acgtcagcgt
    14581 cgtcttgccg taggatagtt gttgactttg tcagttttat ctacaacctc aaaacagtgt
    14641 tttgagctgt ctgcgcctag ctttctagtt tgctctttga tttttattga gtataccact
    14701 attttactcc ctctggcaag gtactttgtc tatgtggagg gattgggctc ctatgtggtg
    14761 gagcttttct gttctttctg aaatatggta taatagcact aattaatttc taggaaaata
    14821 gatacagaaa ggggctgaaa gatgtctcat attattgaat tgccagagat gctggcaaac
    14881 caaatcgcag ctggggaggt cattgaacgt cctgccagtg tggttaaaga gttggtagaa
    14941 aatgccattg acgcgggctc tagtcagatt atcattgaga ttgaggaagc tggtctcaag
    15001 aaggttcaaa tcacggataa cggtcatgga attgcccacg atgaggtgga gttggccctg
    15061 cgtcgccatg cgaccagtaa gataaaaaat caagcagatc tctttcggat tcggacgctt
    15121 ggttttcgtg gtgaagcctt gccttctatt gcgtctgtta gtgtcttgac tctgttaacg
    15181 gcggtggatg gtgctagtca tggaaccaag ttagtcgcgc gtgggggtga agttgaggaa
    15241 gtcatcccag cgactagtcc tgtgggaacc aaggtttgtg tggaggatct ctttttcaac
    15301 acgcctgccc gtctcaagta tatgaagagc cagcaagcgg agttgtctca tatcattgat
    15361 attgtcaacc gtctgggctt ggcccatcct gagatttctt ttagcttgat tagtgatggc
    15421 aaggaaatga cgcggacagc agggactggt caattgcgcc aagcaatcgc agggatttac
    15481 ggtttggtca gtgccaagaa gatgattgaa attgagaact ctgacctaga tttcgaaatt
    15541 tcaggttttg tgtctttacc tgagttgact cgggctaacc gcaattatat cagcctcttc
    15601 atcaatggcc gttatatcaa gaacttcctg ctcaatcgtg ctattttgga tggtttcgga
    15661 agcaagctta tggttggacg ttttccactg gctgtcattc acatccatat cgacccttat
    15721 ctagcggatg tcaatgtgca tccaactaag caagaggtgc ggatttccaa ggaaaaagaa
    15781 ctgatgaccc tggtttcaga agctattgca aatagtctca aggaacaaac cttgattcca
    15841 gatgccttgg aaaatcttgc caaatcgacc gtgcgcaatc gtgagaaggt ggagcaaact
    15901 attctcccac tcaaagaaaa tacgctctac tatgagaaaa ctgagccgtc aagacctagt
    15961 caaactgaag tagctgatta tcaggtagaa ttgactgatg aagggcagga tttgaccctg
    16021 tttgccaagg aaaccttgga ccgattgacc aagccagcaa aactgcattt tgcagagaga
    16081 aagcctgcta actacgacca gctagaccat ccagagttag atcttgctag catcgataag
    16141 gcttatgaca aactggagcg agaagaagca tccagcttcc cagagttgga gtttttcgga
    16201 caaatgcacg ggacttatct ctttgcccaa gggcgagatg gactttacat catagatcag
    16261 cacgctgctc aggaacgggt caagtacgag gagtaccgtg aaagcattgg caatgttgac
    16321 cagagccagc agcaactcct agtgccctat atctttgaat ttcctgcgga tgatgccctg
    16381 cgtctcaagg aaagaatgcc tctcttagag gaagtgggcg tctttctagc agagtacgga
    16441 gaaaatcaat ttattctacg tgaacatcct atttggatgg cagaagaaga gattgaatca
    16501 ggcatctatg agatgtgcga catgctcctt ttgaccaagg aagtttctat caagaaatac
    16561 cgagcagagc tggctatcat gatgtcttgc aagcgatcta tcaaggccaa tcatcgtatt
    16621 gatgatcatt cagctagaca actcctctat cagctttctc aatgtgacaa tccctataac
    16681 tgtcctcacg gacgtcctgt tttggtgcat tttaccaagt cggatatgga aaagatgttc
    16741 cgacgtattc aggaaaatca caccagtctc cgtgagttgg ggaaatatta aaagtataaa
    16801 aaagtctggg aaaaattttc aaaatcagaa aaacgcataa aatcaggtgt tcaaaaacct
    16861 tgattttatg cgttttatca tagaaatatt tacttcatgt tttcctaatt cttttcgaaa
    16921 ctctttttaa accacgtcag ttttatcagt aatctcaaaa cagtgttttg agctaatttt
    16981 gccagttttg tctgtaacat cgaagttgtg tttgaccact ctgcgactgg tttcctagtt
    17041 tgctctatga ttttcacaga gtattaaatt gcgattttgc caagtttctt tattcgtcta
    17101 aaagtagagt ctgttctatg cgtctaatgt acgaattagg ttgaccattt caatagctcc
    17161 ttgtgcacac tcagaaccct tatttcctgc tttagtacca gctcgttcta tggcttgttc
    17221 aattgtatct gtcgttagca caccaaacat aacaggaatt tcgctattta aactgatttg
    17281 ggcgattcct ttagatacct cgctacatac ataatcataa tgacttgtat tccctctaat
    17341 gacagctccc aagcagataa ttgcatcata ttttttactt tttgccattt ttgatgcaat
    17401 cagtggtatt tcaaaagctc ctggaaccca ggctacctcg atatctttct cgtttacatt
    17461 ctctcttttg agattatcta gtgctccaga taataatttt gaagttataa attcattaaa
    17521 tctcgctaca acaataccta ttttaatatt gtttgctact aaattacctt cataagtgtt
    17581 catttatttt tcctccatat ttaaaatgtg acccattcga tttttctttg tttctaaata
    17641 aaaactatcg taaggattgg cttctatttc gattgatatt ctactggaaa tggtaattcc
    17701 atatttttct aactgttcaa ccttgtcagg attatttgtc agtaaatgaa gtgactgaag
    17761 tcccagatct ttaagcattt gtgctccaat atgatattct cttaaatcac cttcaaagcc
    17821 taatgcaaga ttggcatcaa gcgtatccat gccttgatct tgtaaatgat aggcttttaa
    17881 tttattgata agtccaattc ctcgtccctc ctgtcgcaag taaagtaaga cacccgaacc
    17941 attctcaaca atcattttca tagctttatc gaattgctgt ccacaatcgc aacgtaaaga
    18001 gcctaaaaca tctcctgtta aacattcgga gtggacccga cataatacat tggcttcatc
    18061 ctctatgttt cccataataa gagcaagatg atgttcccca tttagtttat ctatatagct
    18121 aattgctttg aaattaccgt atctagtagg catattgaca gttgaaactc gttctaccag
    18181 ctgatcatat acttttctat attcttgtaa ttctttgatg gtaattagtg gaatgttgtg
    18241 tttcttcgag aactgaatta aatcatctgt tctcatcatt ttgccatcat gattcattat
    18301 ttcacaacat aggccacact cttttagtcc agctaatttt aataaatcaa cagttgcttc
    18361 tgtgtgtcca tttctttcta gaacaccacc tttttttgca attaaaggaa acatgtgtcc
    18421 tggcctgcga aaatcagagg gtgttatatc ttcagctaca cacatacgtg cggtcagtcc
    18481 tctttcctcg gcagaaatac ctgtggtcgt ttctttataa tcaattgaaa ctgtaaaagc
    18541 agtcttatga ttatctgtat tgttttcaac cataggtgaa agcattaatt gattagctaa
    18601 actttcgctc ataggcatac aaattaatcc tttggcataa gtagccataa aattaacatt
    18661 ttctgttgta gctgcttgtg cagaacaaat taagtctcct tcattttctc tatccttgtc
    18721 gtctataaca agaacaagtc gtcccttctg caatgcttct aatgcttctt gtatttttcg
    18781 atattccatt gactgattat cctttctgct aaaatccatt ttgatataat agttccttcg
    18841 atatttctga ttttggagag ttatccatca gtttttgcac atatttacct aagatatcat
    18901 tttcaagatt tactgtactc ccgacttgtt tactcttaag aatggtttgt ttcaaggtat
    18961 gagggataac agatactgaa aagtttactt tggagacttt agcgacagtc agactaatgc
    19021 cgtcaattgt aatagatcct ttttcaacta ttaaatctaa aatttctttt tgtgtgttga
    19081 tttgatacca tacagcatta tcatcttttt ttattgacga gatttttcct gtaccatcaa
    19141 tgtgtcctgt aacgacgtga cccccaagtc gaccgttgac agataaggct ctttctagat
    19201 tcacctcact tccatgtttt aatagagtaa gagctgttcg actccatgtt tcattcatta
    19261 catcaactgt aaaggattga tgattgaaat gagtaactgt aagacagata ccatttactg
    19321 ctatactatc gcctaaatgg atatccgtta atatttttga ggctttaatt gatagtttac
    19381 aattacgaga gtctttctgt attctttcaa cttttccgat ttcttcaatt attcctgtga
    19441 acatggataa atcacttcac tttctatgag atagtcattt cctatttgag aaaaagcata
    19501 aggtttcaat ctaatagcgt catttggcaa agaaatgcct tcacctccga caggaaactt
    19561 ggcactgcct ccaaaaattt ttggtgcaat atatattttc agctcatcaa caatttgttg
    19621 ttccaaagca ctccaattca ttagactgcc cccctctaga actaggctat caatctgcat
    19681 gtttcctaga tgttgcatta aactcgataa gtctatatga ttgccttttt tctttatgga
    19741 aagtatttca cagccatgat tttgatatag cttcatttta tttttgtctt cagaggaagt
    19801 ggcaatgtaa gttttaatat catttgctgt ttttacgatt ttagaggtaa gaggagttcg
    19861 taaatgtgta tcgcatatga tacggatagg atttttccct tcctccaatc tacatgtcag
    19921 caaaggatcg tcttgaataa cagtattgac tcccaccata attgcactaa catagtgtcg
    19981 taactgatgc acatgctttc ttgcttcttc ttcagtaatc catttggatt gatttgtttt
    20041 agtggctatt tttccatcca ttgacattgc atatttcata aaaacatagg gtacatgctg
    20101 ggtaatatac tttctaaaac tttttattaa gttaagacac tcattttcta aaattccaac
    20161 agtaacttga agattatttt cctcaagtat ctttactcct tttccagata caataggatt
    20221 acagtctagg cttccaatga ctactcttgt aataccacta tcgattatag catctataca
    20281 gggaggtgtt ttcccgaagt gacaacaggg ttcaagtgtt acataaagcg tcgctccgac
    20341 aggggatttt ctacagtttt taagagcatt tctctcagca tgtgggccac caaaaaactc
    20401 atgataacct tgtccgataa tgtgattatc ttttacaata attgcgccaa ccataggatt
    20461 gggattgacg taaccagccc ctttttgtgc cagttttatt gctaatttca tatattttga
    20521 atcgctcatc tcactacctc caaaaaaata taccttgaat aggggactac tcaaggcata
    20581 caaaagaaaa cttatgcgat taacaaaaat gctctgaaat gacaagtaat catttcagag
    20641 cacgcaaaaa gcacaaatat acttttatct tctttcatcc agactatact gtcggctttg
    20701 gaatttcacc aaatcatgcc tttcggctcg tgggctatac caccggtagg gaattgcacc
    20761 ctgccctgaa gatagttatt caattacaga tgattatagt acttaatttt gaatatgtca
    20821 acagataaat acagattgtt tttgatatac tgtatttgtg ataatcgatt ctcgctcctc
    20881 ggataaagaa aatatgatat actagataaa cgaaataaga gagaaggaac actatgtacg
    20941 catatttaaa aggaatcatt accaaaatta ctgccaaata cattgttctt gaaaccaatg
    21001 gtattggtta tatcctgcat gtggccaatc cttatgccta ttcaggtcag gttaatcagg
    21061 aggatcagat ttatgtgcat caggttgtgc gtgaggacgc ccatttgctt tatggatttc
    21121 gctcagagga tgagaaaaag ctctttctta gtctgatttc ggtctctggg attggtcctg
    21181 tatcagctct tgctattatc gctgctgatg acaatgctgg cttggttcaa gccattgaaa
    21241 ccaagaacat cacctacttg accaagttcc ctaaaattgg caagaaaaca gcccagcaga
    21301 tggtgctgga cttggaaggc aaggtagtag ttgcaggaga tgaccttcct gccaaggtcg
    21361 cagtgcaagc aagtgctgaa aaccaagaat tggaagaagc tatggaagcc atgttggctc
    21421 tgggctacaa ggcaacagag ctcaagaaaa tcaagaaatt ctttgaagga acgacagata
    21481 cagctgagaa ctatatcaag tcggccctta aaatgttggt caaataggag cagagaatga
    21541 caaaacgttg ttcgtgggtc aagatgacca acccgctcta catcgcctat catgatgagg
    21601 agtggggtca gcccctccat gatgaccaag cattgtttga gttgttgtgt atggaaacct
    21661 atcaggcagg cctgtcttgg gaaacggtac tcaacaaacg ccaagctttc cgagaagcct
    21721 ttcatagcta tcaaattcac tcagtcgcag agatgactga cactgaattg gaagccatgc
    21781 tggagaatcc agctatcatt cgaaatagag ccaagatttt tgctacacgc gctaacgccc
    21841 aagcctttct acagttacag gcagagtacg gctcttttga tgcctatctt tggtcttttg
    21901 ttgaggggaa aactgtcgtt aacgatgttc ctgattatcg ccaagcccca gctaaaacac
    21961 ccttatctga gaaattagcc aaagatctca aaaaacgagg cttcaagttc acaggcccag
    22021 tcgccgtatt gtcttttcta caggctgcag ggctagttga tgaccacgag aatgattgtg
    22081 agtggaaagg tcttaaatga tgtctaacaa aaataaggga attctgattt ttgtgattct
    22141 ctatacagtc ctctttgtgt ttgatggcgt taaattgctg gcttctttaa tgccatttgc
    22201 cattgcaaat tatcttgttt atgtagtttt agctttatat ggctccttct tgttcaagga
    22261 tagattgatc caacaatgga aggagattag aaagactaaa agaaaattct tctttggagt
    22321 cttaacagga tggctctttc tcattctgat gactgttgtc tttgaatttg tatcagagat
    22381 gttgaagcag tttgtgggac tagatggaca aggtctaaat cagtctaata ttcaaagtac
    22441 ctttcaagaa caaccactac tgatagctgt ttttgcttgt gtcattggac ctctggtaga
    22501 agaattattt ttccgtcagg tcttattgca ttacttgcag gaacggttgt caggtttact
    22561 aagcattatt ctggtaggac ttgtttttgc tctgactcat atgcacagtt tggctctatc
    22621 agagtggatt ggtgcagttg gttacttagg tggaggcctt gccttttcta ttatttatgt
    22681 gaaagaaaaa gagaatatct actatcccct acttgttcac atgttaagca acagcctctc
    22741 cttaatcatt ttagctatca gtatagtaaa atgaaataag aacaggacaa atcgatcagg
    22801 acagtcaaat cgatttctaa caatgtttta gaagtagagg tgtactattc tagtttcaat
    22861 ttgctgtaat atgtgatgaa aatgccagta ataataccga gaaaaaagct gagaaacttt
    22921 tcccagcttt atttgttata gtcaaagcga atgacttgtt cctgtgcatc tacatgagca
    22981 tgaaccccaa agggtacaat tgctcttgga gttgcgtggc cgacattcag attatagaca
    23041 atcgggatat tgctgtcaat gatatccaat agtgcctctt tatagtcgtc atggaaagtt
    23101 tcatccatag gttttccgac caagagtcca ttgatgaccg cgaatatgcc agtgtccttt
    23161 aaagttagca acatcttttt gaagtcttct ggtttaggct tttcttcgct tgtttcgagc
    23221 aagaggattt tcccttccca gtctgacaag tcagggaaaa gtttgtattt ttggcagagt
    23281 tccgtgctat ctgcgtatcg agagttgtca aagatatcgt agagggattc gaggcaacca
    23341 ccgaggattt tcccctcgaa ctgagcactt ccttgcaaca agtcaaaacc tgtatttgta
    23401 tgactgacac gaggtgttcc cagggctgtg ggactaaaat cagttcgttc ctcataccaa
    23461 acgtcactag ggcggatttc tgaaattctt cccgtcttaa tcaattcttt aaagtagtga
    23521 aggctatagg ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa ggattgacca
    23581 taaaaagtct tgattcctaa tttatgcaac atgaggtggt tcatggttgt atccgagaag
    23641 ccaagaaaaa ttttttgctt gataaccttt tggagttggt cattttcaaa aagataaggt
    23701 agcaagcgat aggtatcgtc tccaccgatg gcacatagga tcatgtcgat gctatcatca
    23761 gaaaaggcat gaatcaaatc ctctgcacga gcttcaggat ggtccttgat aaagtctaat
    23821 ccttttaacg aatgggacaa aaagatggga ttgagtccca gatgcttgag acgttggata
    23881 cccaagtcca cttcgtgttt gacaaaatcc tctccgataa tgccactaga taaactaaca
    23941 ataccaatag tagaaaccat atctcatcct cctagaaata gattgagcct attttatcac
    24001 aaaatataag agaaagctat gtgggatttc agaagaatac ttttaatact cttcgaaaat
    24061 ctcttcaaac cacgtcagtt ttatttgcaa cctcaaagct gtgctttgag caacctgcag
    24121 ctagcttcct agtttgctct ttgattttca ttgagtataa ctcaaaaaag taagtgaaaa
    24181 agcaaccgca cctgcagttg cttttatcgt tttcttattc ttgatagcgt gttggtcctg
    24241 cacttgcact acggatattc aagcgtttct tgagatagaa gcgaagggct aggagggctg
    24301 ctccaataat agctagtggc aatggatcca gtactgggtt aaggctagct ggtaggaagc
    24361 ttgttgcaaa gaagacaagc aaccaaagga acatagaagc taggataact agtacagatt
    24421 tccagaaagg tggacgttga ctgcggtcca tatctggtcc atagtattgg taaacaaagt
    24481 agtacatcaa gtagaaggca aatccaccaa ccagtccaac taatagaaga gtaatcaatc
    24541 catagccgaa agcttgatct gccgcaaaga aggttgtgag ggcgctgaca agggcaaaga
    24601 ggctagtgat gaaaagagct gagtccataa tcatcagttt tggatcatca ttttcttttg
    24661 gatgctcttt ttcgtactgc tctttgacag tgaagctatg agcccaatga gttggtgcgc
    24721 cgtataggga acgggcagtt gtacctttag attgctcctc aaggatttgg ggaatgactt
    24781 cctcaaaaat agtctggatt tcagcgtctg ttttcccatc tttgatgaat tgttgggtag
    24841 caatgtggac aaactcttgg tttttcttag ttaatttttg tagatcaatt tgagacatag
    24901 gaactcctct tagaaccatt ttttatggat gagatagaga gtgagcgaga cactcatagc
    24961 aaaggcgata aagacgatta accagaaggc atttggctct ccgtttaggg ggatttcatt
    25021 atccttaaag ttcatcccgt aggcagaaaa gaccatggtt gggatggaca tgacgatggt
    25081 cacaagggcc aaggttttca tgatgttgtt ctggttgtta gaaatgatag aggcaaaggt
    25141 ctctgtcata gaatgcaaga cgtttccata aatatctgcc atctcgatgg cctgttgggt
    25201 ttcaatcagg gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga tattgctggt
    25261 tgaactggtc aatttcttaa tcacgcgctc atttgttttg agggaggcct tgaaatagac
    25321 gatagttttt tccaattcca tgagctcaat caattcttca ttacgagttg attgatgcag
    25381 ttgactttcg atttgttcac tcttgcggtc gattgaacga agggctgtta ggtaaagctc
    25441 tgcattgcga taaagaattt gaaagataaa acgtgaacgc atgaaggtat agaaattacg
    25501 caatcgacgg ttgataaaga catcaaggac aggtagtggt tccaaacacg tagtgataat
    25561 ggtttcctca gtgatgataa taccaagcgg gatggttacg tagtaggtgc ggttatttct
    25621 ttcctccgtg accggcacgt ctacgataat cagggtatac tcgtcttcaa tggtaatacg
    25681 agacatttct tccgcatcga gcggtgctcg aaggtcggca atatcaatat cgaaggtgtt
    25741 ggcgatttcg agtgattcat tttgagtcgg attgacgaga ttgatccaag tacccggttc
    25801 aagcgtatcg atctctttaa attcagttgt tgtagagaga aaaacttgtt tcatatccct
    25861 tatcctttct catttttcag attttttcac actgtactat tatactacaa aatcggcctt
    25921 ttgggtaata gaatctcact ttttttggta taatggtaag caataatgga ctagaaagaa
    25981 caaagatgca agataaaatt gtcattcatg gggcgcgtgc ccataattta aaaaatattg
    26041 atgtggagat tccgcgagac aagttggttg tcgtgactgg cttgtcaggt tcagggaagt
    26101 ccagtctggc ttttgatact ctctatgcgg agggacaacg tcgctatgta gagagtttgt
    26161 ccgcctacgc tcgtcagttc ttgggaaata tggaaaaacc agatgtagat gccattgatg
    26221 gtctcagccc agctatttcc atcgaccaga aaacgactag taaaaatcct cgctcgacgg
    26281 tgggaacgac gactgaaatc aatgactatc tgcgtctcct ctacgcacgt gtggggacgc
    26341 cttactgtat caacggacat ggagctatca aggcttcttc tgtggagcaa atcgttgata
    26401 aggttttgga gttacctgaa cgccagcgct tgcagatctt ggctcctgtc atccgcaaga
    26461 aaaaaggcca acataagagt gttatcgaga aggttcagaa agacgggtat gttcgtgttc
    26521 gtgtggatgg ggaagtctat gatgtgaccg aagtgccaga gttgtctaag agcaagcaac
    26581 acaatatcga tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt agtcgtctct
    26641 ttgattccat tgaggctgcc cttcgtattg cagaaggtta tgtcattatc gacaccatgg
    26701 acgattcgga gttgctcttc tctgagcatt atgcctgtcc agtttgtggt tttactgtcc
    26761 cagagttaga gcctcgtctc ttctctttca atgctccttt tggctcttgt agtgagtgtg
    26821 acggcttggg catcaagctg gaggtggata ctgatttggt agtgccagat gccagcaaaa
    26881 ccttacgtga gggagcgcta gcaccttgga atcctatctc atccaactac tatccaaaca
    26941 tgttagagca ggccatgaaa gtctttggag tggctatgga taagcctttt gaggacctgt
    27001 cagaagaaga taagaacttg attctctatg ggtcagatgg taaggaattc catttccact
    27061 atgagaatga atttggtggc gtgcgcgata tcgacattcc gtttgaggga gttatcaata
    27121 atatcaaacg tcgttaccat gaaaccaata gcgattacac tcgcactcag atgcgtctct
    27181 acatgaatga gctgacctgc ggaacctgtc aaggctatcg tctcaatgac caggccttgt
    27241 ctgtccgtgt gggcggccag caagggccac atattggaga aatctcagac ctgtctatcg
    27301 ctgaccactt ggacttggtg agccagttaa ctttgtctga aaatgaagcc atcattgctc
    27361 gtcccattct caaggaaatc aaggatcgtt tgaccttcct taataatgtg ggtcttaact
    27421 atctaaccct gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag cgcattcgtt
    27481 tggcaaccca gattggttcc aacctatcag gcgtcctcta tatcctagac gagccgtcaa
    27541 tcggtcttca ccagagggac aatgaccgcc tgattgccag tctgaaaaag atgcgtgact
    27601 tgggcaatac tcttatcgtg gtggaacacg acgaagatac catgcgtgag gctgattatc
    27661 tgattgacgt tggtcctggt gccggtgttt ttggtggtga gattgttgca gcaggtacac
    27721 ctaagcaagt ggctcgcaac agcaagtcta tcacaggtca gtacttgtca ggcaaacgtg
    27781 tcatcccagt accagaagag cgccgtgtcg gaaatggtcg ttttattgaa gtgataggag
    27841 cgcgtgagaa caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa tttatcgcag
    27901 tgacaggtgt gtcgggttca gggaaatcga ctctaatcaa cagcattctc aaaaaagcca
    27961 ttgcccagaa gctcaaccgt aattcagaca aacctggtaa gtttaagact attacaggga
    28021 ttgagcatgt cgaccgtttg attgatattg accagagccc tatcggacgg acgccgaggt
    28081 ctaacccagc tacctataca ggagtttttg atgatatacg tgaccttttt gctcagacaa
    28141 atgaagccaa gattcgaggc tacaagaagg ggcgcttcag tttcaacgtc aagggaggtc
    28201 gctgtgaagc ttgctcaggt gacgggatta tcaagattga gatgcacttc ttgccagatg
    28261 tttatgtggc ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc ctagaagttc
    28321 actacaagga aaagaatatt tcgcaggtct tggatatgac ggtcaacgat gcggtagaat
    28381 ttttccaaca cattccgaaa attcaacgca aactccagac catcaaggat gtaggtctag
    28441 gctatgtgac cttgggacag ccagctacca ccctttctgg gggagaagcc caacgtatga
    28501 agttagctag cgaactccac aaacgctcga caggaaaatc tttctacatt ctggatgagc
    28561 cgacgacagg gcttcataca gaggacattg ctcgcctgct caaggtttta gctcgctttg
    28621 tagacgatgg caatacagtc ctcgtcatcg agcacaatct ggatgttatc aagacggcag
    28681 accatatcat tgacttggga cctgagggcg gtgtcggtgg tggaaccatc atcgtaacag
    28741 gaactccaga agaagtagct gccaacgaag ccagctatac aggacactat ttgaaaggaa
    28801 agttacatca tggataaacg cgtacaagca tttctagcta aaatgcaaga aaaagaacta
    28861 gatggtatca tcatcaacaa tcttaaaaac gtctattatt tgactggttt ttggggctca
    28921 aacggaacag tctttatcag ccgtgaccgt caggtcttag tgacagactc tcgctatatc
    28981 atcgcagcta agcaagaaac cagtggtttt gagattgtgg ctgatcgtga tgaattggct
    29041 gtcattgcag gaattgttaa ggacatgggc ttgactcgta tcggttttga agatgagatt
    29101 tcagtgtctt attaccaccg tatgcaggca gcttttgcag gtttggactt gcttccacaa
    29161 actcagtttg tggaaggtct tcgtatgatt aaggatgagg cagagattgc agcgattcgc
    29221 aaggcttgtt ctatctcaga ccaagctttc cgcgatgcgc ttgactttat caaaccagga
    29281 aaaactgaaa ttgagattgc caacttcctt gatttccgca tgcgtgagtt gggagcatct
    29341 ggcttatctt ttgatacgat cctagctagc ggtatcaatt cttctaaacc ccatgcccat
    29401 ccaatgcaca aaccagtgga gttgggagaa gccattacca tggacttcgg ctgtctctat
    29461 gaccactatg tcagtgatat gacccggact atctatctag ggcatgttag cgatgagcag
    29521 gcagagattt acaatacggt tctaaaagct aaccaagcct tgattgacca agctaaggca
    29581 ggcttaggtt tccgtgactt tgacaaaatc cctcgtgata ttatcattga ggcaggttat
    29641 ggtgactact ttactcacgg cattggccac ggtattggtc tggatatcca tgaggaaccc
    29701 tactttagcc agacttctac agaaactatt aagacaggta tggccttgac cgatgaacca
    29761 ggtatctata tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct gattacagag
    29821 acaggttgtg aattattgac cctagctcca aaagagttga tagtcattta gttgtttgtc
    29881 aagaaaaaag tacgaaaatg acgaaaaaag tcaaaaaaaa ttaaaa
//
LOCUS       DAVKBC010000024        28443 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVKBC010000024 DAVKBC010000000
VERSION     DAVKBC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28443
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.024"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..279)
                     /locus_tag="VWX64_001237"
     CDS             complement(<1..279)
                     /locus_tag="VWX64_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9190709.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWRGRSAVLNQHIFKVVLDKI"
     gene            complement(313..1278)
                     /locus_tag="VWX64_001238"
     CDS             complement(313..1278)
                     /locus_tag="VWX64_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9190710.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1396..1809)
                     /locus_tag="VWX64_001239"
     CDS             complement(1396..1809)
                     /locus_tag="VWX64_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU9190711.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1806..2042)
                     /locus_tag="VWX64_001240"
     CDS             complement(1806..2042)
                     /locus_tag="VWX64_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU9190712.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            complement(2102..2503)
                     /locus_tag="VWX64_001241"
     CDS             complement(2102..2503)
                     /locus_tag="VWX64_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9190713.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            complement(2516..4009)
                     /locus_tag="VWX64_001242"
     CDS             complement(2516..4009)
                     /locus_tag="VWX64_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9190714.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            complement(4517..5236)
                     /locus_tag="VWX64_001243"
     CDS             complement(4517..5236)
                     /locus_tag="VWX64_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9190715.1"
                     /translation="MIAKPDNGVGAAATFKLETEDDINHFKQEWDHSTLYFFEKFVTS
                     SEICTFDGLVNKDGKIVFSTTFDYAYTPLDLMIYKMDNSYYVLKDMVPKLRKYGEAIV
                     KEFGMKERFFHIEFFREGDDYITIEYNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGE
                     EFPASEFEPQYCLATSRRANAHYVYSEENLLAKYSQQFKVKKIMPEAFAELQGDYFYM
                     LTTPSRQEMDQMIADFGQRQE"
     gene            complement(5254..5661)
                     /locus_tag="VWX64_001244"
     CDS             complement(5254..5661)
                     /locus_tag="VWX64_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoylphosphate synthase"
                     /protein_id="HEU9190716.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPINRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKQ"
     gene            complement(5719..6414)
                     /locus_tag="VWX64_001245"
     CDS             complement(5719..6414)
                     /locus_tag="VWX64_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU9190717.1"
                     /translation="MHIEHLSHWSGHLNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGLVQFFTLSSLDSESWLATWKNAHDQAEMHRAYERYVIEEAIPFI
                     KHKTGWFDGMMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYYNDDAI
                     YQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDQKQIPAW
                     FAEWGHDVAHDWE"
     gene            complement(6436..7260)
                     /locus_tag="VWX64_001246"
     CDS             complement(6436..7260)
                     /locus_tag="VWX64_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9190718.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(7397..8611)
                     /gene="thiI"
                     /locus_tag="VWX64_001247"
     CDS             complement(7397..8611)
                     /gene="thiI"
                     /locus_tag="VWX64_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU9190719.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGFVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(8620..9762)
                     /locus_tag="VWX64_001248"
     CDS             complement(8620..9762)
                     /locus_tag="VWX64_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9190720.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            9900..10328
                     /locus_tag="VWX64_001249"
     CDS             9900..10328
                     /locus_tag="VWX64_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190721.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKKDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            complement(10479..12704)
                     /locus_tag="VWX64_001250"
     CDS             complement(10479..12704)
                     /locus_tag="VWX64_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU9190722.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     INENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(12868..14820)
                     /locus_tag="VWX64_001251"
     CDS             complement(12868..14820)
                     /locus_tag="VWX64_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9190723.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIEEMIKSLTGHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALTELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLAISGDAEVYRAANGAK
                     VATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(14817..15728)
                     /gene="pfkB"
                     /locus_tag="VWX64_001252"
     CDS             complement(14817..15728)
                     /gene="pfkB"
                     /locus_tag="VWX64_001252"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU9190724.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNISNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVKLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(15725..16465)
                     /locus_tag="VWX64_001253"
     CDS             complement(15725..16465)
                     /locus_tag="VWX64_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9190725.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYLLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            16627..16714
                     /locus_tag="VWX64_001254"
     tRNA            16627..16714
                     /locus_tag="VWX64_001254"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16661..16663,aa:Ser,seq:gga)
     gene            complement(16884..17231)
                     /gene="ssrA"
                     /locus_tag="VWX64_001255"
     tmRNA           complement(16884..17231)
                     /gene="ssrA"
                     /locus_tag="VWX64_001255"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(17877..18986)
                     /locus_tag="VWX64_001256"
     CDS             complement(17877..18986)
                     /locus_tag="VWX64_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9190726.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            19089..20330
                     /locus_tag="VWX64_001257"
     CDS             19089..20330
                     /locus_tag="VWX64_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU9190727.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIEQI
                     GNQSSQSVQFTPDSKAIPAPLEARTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            complement(20561..21973)
                     /gene="sufB"
                     /locus_tag="VWX64_001258"
     CDS             complement(20561..21973)
                     /gene="sufB"
                     /locus_tag="VWX64_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU9190728.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(22027..22467)
                     /locus_tag="VWX64_001259"
     CDS             complement(22027..22467)
                     /locus_tag="VWX64_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU9190729.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(22454..23680)
                     /locus_tag="VWX64_001260"
     CDS             complement(22454..23680)
                     /locus_tag="VWX64_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9190730.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDRVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(23691..24953)
                     /gene="sufD"
                     /locus_tag="VWX64_001261"
     CDS             complement(23691..24953)
                     /gene="sufD"
                     /locus_tag="VWX64_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU9190731.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(24981..25751)
                     /gene="sufC"
                     /locus_tag="VWX64_001262"
     CDS             complement(24981..25751)
                     /gene="sufC"
                     /locus_tag="VWX64_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU9190732.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(25901..26095)
                     /locus_tag="VWX64_001263"
     CDS             complement(25901..26095)
                     /locus_tag="VWX64_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU9190733.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(26123..27778)
                     /gene="dnaX"
                     /locus_tag="VWX64_001264"
     CDS             complement(26123..27778)
                     /gene="dnaX"
                     /locus_tag="VWX64_001264"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU9190734.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(27778..28275)
                     /locus_tag="VWX64_001265"
     CDS             complement(27778..28275)
                     /locus_tag="VWX64_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU9190735.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
BASE COUNT         8497 a         6204 c         5166 g         8576 t
ORIGIN      
        1 tatcttatcc aaaaccactt taaaaatgtg ctgatttaac actgcggatc ttccacgcca
       61 ctgaaaaacc cctaatgtac ccgaccacga aataagaata tcaccagctt caacaatgta
      121 ttttttatca atcgtacccg aataataatt tatctctgtt gaagttttag tcagattctg
      181 tattctgata atctctttcc cttcagatga ccaatcttga ggtttaaaag catagccatt
      241 gataaaagta gccacttcac ctaatttcac tttcttcatg caaccacctc ctcggaatat
      301 cgggatttgc ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac
      361 catggcatag gccagggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc
      421 gataggcata cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg
      481 aaccttttgt atgccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat
      541 tccaagtctc tgggcttttc caactagcgt tacaaaaaga gcagggtgac tatcttttct
      601 gtcgttaaga taatttctta aatgaatttt cgtccgagcg tcaaaatata ctggtctctc
      661 cttctttcct ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt
      721 caactgtaca agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa
      781 atctctcaaa ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc
      841 cttcacattt tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata
      901 ttcctcttgc tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt
      961 tgccttacta caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt
     1021 tgtgagttgt gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctggta
     1081 ataacgaatt gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa
     1141 caggttatta ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact
     1201 ctctctcaac gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat
     1261 tgtaactttt gattccataa tttctcactt tcttattcat caataaaaag agacaatatc
     1321 agtttctgca ttacagaatt ctaatattgt ctgttcattt attttcttgt gctcattcaa
     1381 atccagcata ctaggttact ttttgacctt ttctctaaca gaatgttcag aaacccattt
     1441 ggagtagctt gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt
     1501 tactgcttct tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa
     1561 aacgaagaaa gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac
     1621 aaatagtatc gttgctttat caaaaattgt tggataaaga gacttcccaa agacaaattg
     1681 ttctggtaag ttcacaatca tatttaaggc agaagaacta actgtttgaa ttttctcatt
     1741 tggagaatac cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcagata
     1801 gattgtcatt tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct
     1861 aaatttaagt caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga
     1921 gtaaagataa tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata
     1981 ttaaattcac ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc
     2041 atctgatttc ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat
     2101 atcagccaaa atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt
     2161 tttggattgc caattgtgat ttactttcca aaaagactcc caagtaatct gatataattt
     2221 tttctttgta tcgctcattc ttttttaaga ccgtaattgt actaccaaca gctcccgata
     2281 atccataacc aactgttcct gcattagctc catcccatgc tatcagaata tcatctggga
     2341 gtgcttcagt catatttaaa ctttcagtga attttaaatt attattattt cttaaatcat
     2401 ctatttgaat ataacgttgg cttagagttg tttgttcagc aagtacagtg gctttcttgc
     2461 ctttttttag agataagact tcccccaact tcactttttt catacagcca cctccctact
     2521 tgagtaattt ttctaattca gccaagccag cttgaatttc tttttctaaa tcattgattt
     2581 tctttaagat gacctctgtt ggttcatact caactttttc atactcaatc tctttatatt
     2641 tattgataga caaatcataa tcattttcct ttatctcagc aactggaaca aagaaagatt
     2701 gatccgttct ctgacgttct gcttcttttt caagatgatg aaagcgttcg ataatatctg
     2761 gaatatcatt gtcgctaatc ggttgtcgct tatcatccaa acttaaacca tccgctttca
     2821 tatcgtaaaa ccagactttg tcagtaccac cattaccagt ttttgtaaag atgagaatgg
     2881 cagttgaaac tccagcataa ggcttgaaaa caccactagg cattgagatt acagcatcaa
     2941 gcttatgatt ctctacaatt tcctgacgaa ttcctttatg agctttagac gaaccaaaaa
     3001 ggacaccatc aggtacgata actgctgctc gtccacctgg ttttaaagtt cgcaagaaaa
     3061 gagaaagaaa gagtaattct gtttttttgg tttttacggt tgcaagaagg tcattagagg
     3121 ttgaattgta gtcaagtgag cccttaaaag gaggatttgc taaaaccaaa gtatatttat
     3181 cggcttcttc attatcttga gacagcgagt caaggtaact gatttgtgga ttttctactc
     3241 catgtagcat catgttcatc gccccaagtc tcaacatagt cgtatccgta tcatttccat
     3301 gaaacatctg attatgaaaa tgattgatat tatctgtatt ggtttcccat tcatctttct
     3361 tacgctttaa gtaacggcta gcagatacta agaagccagc agaacccata gcgggatctg
     3421 agatgatatc tttgatagtc ggttgcatca actcaaccat catatcgatg atgtgacgag
     3481 gtgtacggaa ctgtccattt ttacctgcgg tcgacaattt tgataacaga tattcataga
     3541 tatctccgat atcagtaata ctttgtttgt cattatcaaa atctacatct aatcccctag
     3601 ttggaaaaac atctaagata gaaattgcct tttgaagcgt agcaggttta tttatttgaa
     3661 aaatagcttc tcgcatatat cgtgaaaagg ctgtatcatc tgtatccccc ttgagatttt
     3721 taataaacgg aaaaatctcc tgagtcatta aacgataaac ttcctgagca tctcctatat
     3781 ttttaaaagt tgaccaacgg tattcaggtt tatcttttgg aaaaactccc tcataaggaa
     3841 tccctagaaa ttcagcatca ctttcacgtc caagctcgac actatccaaa tctttcataa
     3901 ataagagata agtcaactgt tcaatatttg ttaaaggatt tgcgtttcct tctgtccaaa
     3961 gaatttccca cagctgatcg attttatttt ttaattcgcc tgtaatcata tcttcccttt
     4021 tctttagttt ttaaaactta gtaatatcat tattttatca gatttcaaac aaagcttcaa
     4081 ttaactatat ctatgcgtca cctgaatatt ttatactctt cgaaaatctc ttcaaaccac
     4141 gtcagcttca ccttgccgta ggtatatgat actgactctg tcagttctat ccacaacctc
     4201 aaaacagtgt tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
     4261 gtattaatag acttgtttgg tatcctgaaa actatatcgt ataggtgtcg tcatggatcc
     4321 ttttagctga tttaaggata cgaaaacaca atactatgac tcaattgaaa tgttaaaatt
     4381 caatttctag ccacctaatc ctgcttcaaa tagttatcga acaagtttta tgatagctac
     4441 cttgttagga tgctcttatt ttttaccaga caaaacaaaa ggattaaggg agtgaatttc
     4501 cttaatccga tagttcttat tcttgacgtt gtccgaaatc agcaatcatc tgatccattt
     4561 cttgtcgact cggagttgtc agcatataaa agtaatctcc ttgaagttcc gcaaaagcct
     4621 ctggcatgat ttttttaacc ttgaactgct ggctatattt ggcaagtaag ttctcctcag
     4681 aatagacata gtgagcattt gcacgacgtg atgtagccaa acaatactga ggttcaaact
     4741 ctgacgctgg gaactcttct cctgcgacaa tggctgcata tccacgatag aggtccaagg
     4801 aatgagcaaa gttataaaca tcaatggtga aaccacctgc agggcggtta ttgtactcaa
     4861 tggtaatata atcgtccccc tcacggaaga actcaatatg gaaaaaccgt tctttcatac
     4921 caaattcctt aacaatcgct tccccatact tgcgtagttt gggaaccata tccttgagca
     4981 catagtagga attgtccatc ttataaatca tgagatcaag cggtgtatag gcgtagtcaa
     5041 aggttgttga gaaaacaatc tttccatcct tgttcacgag cccgtcaaag gtacagattt
     5101 cgctggaagt gacaaatttt tcaaagaaat aaagggttga atggtcccat tcttgcttga
     5161 agtgattgat atcgtcttct gtctcaagtt taaaggttgc ggctgctccc actccattat
     5221 caggtttggc aatcattgga agaccgattt ctttcactgc ttgataacag ctccaggtac
     5281 cacaggaaca cctgcttttt tgaaaagttt cttcatttca gacttatatt tcgtcttttt
     5341 gagatcctct ggtttggcac caaaaacatt gaattgttct ctgagtgttg cgtctagctc
     5401 aagccagtat tcattgtgag actcgatgcg gttaattgga ccatgtttat aaaagagaaa
     5461 agccactgca cgtttgactt catctatgtt ctcaagatta tcaacacgaa aatactcggt
     5521 caagctattg cgcaagggct catccaattg ctcgtaagac tcttgaccaa ttcccaagac
     5581 tgtgatgcct ttattagcta gttcgatggt aaactgttga aagttttgtg gatagtaggg
     5641 agaaataaca aggtaattca taggtaactc cttttataaa tagagattac cgaggaaata
     5701 aggcatttgt ttacgccatc attcccagtc gtgggcgaca tcatgtcccc attcagcaaa
     5761 ccaggctgga atttgtttct ggtcaaaggc ttctttgagc ttgtaaaagg atggcaaacc
     5821 atcttgttcc caggctccaa gccccgtaca cagcacaatc tctgcctgac ggtaacggtc
     5881 aataaaccag ccatcgtttt ggttccaaat ataatctact ggcgagtttt ggtaaatagc
     5941 atcatcgttg tagtaatcac cgacaaagaa acgtgcgtcg taaacaccac tgagagcaat
     6001 cactttagta aagacatctg gatgctggag gaagaaattg agtgcatgat aggctcccat
     6061 agagcaacct gtcgtcatca tgccatcaaa ccaacctgtc ttgtgcttga taaaaggaat
     6121 ggcctcctca atcacataac gttcgtaggc acggtgcatt tccgcttggt catgagcatt
     6181 tttccaagta gccaaccaac tctcactatc caaactagat agggtaaaga actggacaag
     6241 gccttcctcg ataaaggaag cacaggcatc aatcatgcca aaatcatagt attcgttgtg
     6301 actaccacct gatgaagcaa agaccacaac tggaatccca ccatgtccat aacggttaag
     6361 gtacatttca cggttaagat gaccactcca gtggctaaga tgttcaatat gcatttcgtt
     6421 ttttcctttc ttaacttacc atttttctgc aaaaaatctc agacaatctg gtagattttc
     6481 tgaccaaggg atttcactat ggatggcacc agactgaact tttagcacaa gattatccag
     6541 atgtactccc cctgctatca aatcatggta atagcaaagc gacgagtcga tataggcttg
     6601 tttgatattg ccatccatca aggtcttgtc tgtatcatct gcttcttctg ttcctacata
     6661 gatgaagatg cgctggtcag gcgatagttt ctggcactcg atatagcggt taaaggcttc
     6721 ttggtggagc cagtttgcag atgaaaaaac gcccaagcaa ccaatttggt cttggtattc
     6781 caaaccgata aactgggtaa tattgcctcc tagtgaggaa ccaatcatag ccgtatgctg
     6841 gcagtctgct tttgtacgat aggtctcatc gataaaaggc ttgaccacct ccatgacaaa
     6901 ctcagcatac tccacaccct taccaccaaa ctgctgctct gggataggag attcttggaa
     6961 cttccaagcc gcatactcat tcattcgccc cataccatca ttgtcaatag caacgacaat
     7021 catgcgactg atatccggat ttcgtttgat agctgggata atcttccatg aatatccaat
     7081 gaaagactct ttgctataaa aaacattttg cccgtcatga aagtatacaa caggatagga
     7141 acggtctgta tctttctcat aatctttagg aagaagaata cgtacacggc gctccttacc
     7201 tgtataagga accttgagtt tgtgttcttt catttttaga taaaagtagg attgattcat
     7261 tgtcagaaaa ctctctatat tcaaaatttt atatcattat atcatgaaaa tagaaaaaag
     7321 ttagtttttt acctgttttt agaaaaaaaa actaactttt tttactgatt ttcgctattc
     7381 ttttggattt tctgaattag agtagattat caatcaagtc atcaacttca tctttttcgg
     7441 cttgaggtgt gatttcagta atcatgattc cagccactgc tcgctcaacc aagccttcaa
     7501 catccatacg cgcttcgtac tgctccgcat tcttaatttt aggatttgtt tttggacgat
     7561 ctggtgcaaa aatggtacaa cagtcttcaa acggttggat tgaaatgtca aaggtatcga
     7621 tttcctgggc gatgtcaatg atttccaact tgtccatggt aaccacagga cgaatgatgg
     7681 gagtgttggt aacagcattg atagccttca tactttcaag ggtttggctg gctacttgac
     7741 ctagactttc cccattgatg ataacaaaac catttcgtac ctcacgaata cggtcagtaa
     7801 tccgcatcat aaagcgacga gttagagtca tcaaataagc ttctggcgct ttggctttga
     7861 tttcctcttg aatctctgtg aaaggcacct cgataaactg gatatttccg ccaaacttgg
     7921 tcaatttacg ggtcaagtcc tgcgctttct tgagggcacc aggactagta tatggtggac
     7981 tagcaaagtg aactgcctcg atatccaccc cacgcttaag agcaagataa cctgctacag
     8041 gtgagtcaat ccctcctgac aacatgagca tccctttacc tgaagttcca actggcaaac
     8101 caccagcccc acgaatggtt tcataagaaa gataggctgc ttcttcacga atctccacct
     8161 gaagattgat gtcaggactt ttcatttgaa cttgcacatt tggaatggct tcgaatacag
     8221 cccctccaag tgtttggttg agttcacgac tatcaagttc aaagttgtgg tcgctacgct
     8281 tgctagaaat cttaaaggtc ataccttcct tgtagatgtc ccgcataatc tcttggacag
     8341 aagacttcaa aacttctaca gatttttcaa ccttataaac aggagaaaag ttttgaattc
     8401 caaaaacttg tttgagagat tctgcaactg ctgtgtaatc agctccattg aggtaagcgt
     8461 gggcacggtc gcgatctgct gttaccttaa cttgggtata gatagacaaa acgtccgaaa
     8521 tattattacg aagtttattg atgaaacgca tacggttttt acccttggtt gacaactctc
     8581 cgtagcgaat cataatttct gaatactgca tgaatgctcc tatcttactt ttctagtttg
     8641 attgtaaatc aattttaact tggtcaaaaa ctgctcgacc tgactcatat cattttccaa
     8701 gtctaggcta agacgcacag ctgacttggc cttatctttg tccactccca tggcaatcaa
     8761 ggtaccggct ggttttcctg ccttagatga acaagctgag gttgttgaga tgaaaatatc
     8821 atagtcttca aaggcgtgaa cgatgacttc acctcgaaca cctttgattc caaaagtcag
     8881 aatatgaggt gcaaagtctt cctcatctga aaagacaaaa atatccggat agttcagaag
     8941 agcttggtga atcactgcct tcatctgccc agtcttgctc ctaaagatat ctagcttttc
     9001 catagataaa cggagagcct tggctgtcgc tgcaatccct gccacatttt cagttgtcga
     9061 acgataatct cgctcctggc caccacctgt aagaagaggt gtaatcttct tgccagattt
     9121 gatatagaca aagccaacac cacggacacc atgaaattta tgactcgaga aggtcgcgca
     9181 atccacccgt tctgtcagat acttttcagt cggaattttg gcaagcgcct gaaccgcatc
     9241 aacgtggaag gaaatagtcg gcttgtctgc caagaattct gaaatagcct caataggttg
     9301 gatagagccg atttcattgt tcacagccat gatggaaacg aggattgtat caggccgtat
     9361 caaacctgct aacgcctcaa catcgaccaa gcctttctta tcaactggag caaaatccac
     9421 ttcaaatcct tgacttttca accagagggc tgactctttg actgctggat gttcaatggc
     9481 tgaaacaatg atgtgcttgc caaactgagc tttttcaaag gccacaccct tgataaccca
     9541 gttatcccct tctgttccac cagaggtaaa gaagatttca tcgcttttct taccgattaa
     9601 atctgcaatc tgttggcgag aagcatctaa gattcgtgtt gcttggtctc ccaaacgatg
     9661 gagactagat gggtttccta aaatttttga agcgacctgc atataggttt caagggcttc
     9721 aggataaggc ttggtcgtcg ctgaattatc aaagtaaatc atgtttctca cgctttctaa
     9781 aatcactccc tctattgtat catgaaacgg agcttgcgac aagaaagggc aatttctctt
     9841 tttttaagat ttttttaaag aaacagagta taataaatca taatcaaagg agagaatgta
     9901 tgtctaacta tcgtagaact tcaaaaccga aaacagaaca tatcaaaaaa ggctttactg
     9961 tttttcaaaa aaccattact actatcggta gtatccttgg tttgattaca gcgggtatca
    10021 cgatcatgaa cgccttggat aataataata aaaatactaa aaaagaacct acgacaagcc
    10081 agacgacaac ctttgtcaaa gaaattcaaa aagaatcccc tcaggaaaat actactccaa
    10141 ataaggaaaa taacacttct caagaaaaaa cacaacaaga agaaacgcca aaatctagcg
    10201 tcaaggaaga gaaaaaaaaa gatcagaaaa cagcaactca ggactctact acacctgcta
    10261 caagtaaacc tgccactgaa aatgaaaaac agcccaatac tccaacttca gaaaataata
    10321 ctcaatgaaa atcaaagagc aaactaggaa gctagccgta ggcagtactt gagtacggca
    10381 aggcaaagct gacgtggttt gaagagattt gcgaagagta taaaagtaat caatagccag
    10441 taaaatagct ccttccaacc ttggaaagaa gctatttttt attgctgcaa tacttttctt
    10501 ggcttggtac cttcagctgg accaatgaca cctgccatct caagctcttc catgagacgg
    10561 gtcgcacggt taaatccaac tgacaaacga cgctgaatca tggatgcact ggctttctgt
    10621 gtttcgataa ccaaagactt agcttcttca aaaagcggat caccaccagc atctccatcc
    10681 gaaaattctc cttcattttc agaaacctca cctggatcaa aactctcatc gtagtctgca
    10741 tctgcctgag tcttgatgaa gttcacaatg cgctcaacat cgtcatccga gataaaggag
    10801 ccttggagac gaactggatg attttcatta atcggtttaa agagcatgtc tcctcgacca
    10861 agaagttttt ctgctccatt ttcatccaaa atcgtacggg agtctgttcc tgatgaaacc
    10921 gcaaatgcta cacgagatgg aacattggcc ttaatcaaac cagagatgac atcaacagat
    10981 ggacgctgag ttgcaagaat catgtggata cctgcagcac gcgccttctg cccaagacgg
    11041 atgatagcat cttccacttc cttgctggcc accatcatga ggtcagccaa ctcatccaca
    11101 atcacgacaa tgaatggtag cggaatttgc ttgtactcag actgggaatt gaactcttct
    11161 accttggcat taaaacctgc aatattccga actcccacct tggcaaagag ttcataacgg
    11221 ttttccattt catccacaac cttttgcaga gccttgctgg ctttgcgtgg attggtcacg
    11281 actggaatca agaggtgggg aatatcattg taaacagata actcaaccat cttgggatcg
    11341 accatcataa atttaacttg atctggtctc gccttcatga gaatgctagc aataatgccg
    11401 ttaactgcta ctgacttccc tgaacccgtt gaacctgcaa ctagcaagtg gggcatttta
    11461 gaaaggtcaa aagctcttgc ggttccatta acagccttcc ctaaaggaat ttccaagaaa
    11521 ttttctgctt tcgtttgcga ttgttcccat agttctcgga aagatacagt ggcaatatcg
    11581 gagttgggca cttcaattcc gattagagat ttcccaggga ttggtgcttc aattcggaca
    11641 tccttggcag ccaaggctag agcgaggtca tctgatagat tggaaatgcg gttgaccctt
    11701 acaccaacag ccggcttgac ttcatacttg gtcactgatg gcccaatttc ggcccgttca
    11761 actgttacct taataccaaa gctagcaaag gttgcttcta agattttgat attttctctg
    11821 acaattttct tctctttaga ctgatctttt ggtttatctg gtgcaaagag ttgtaagctt
    11881 ggaagtttgt attcaagggc ttctttggct gaaaaatcga cctgaacatc ttcgtcatct
    11941 gagtcatctt cctgttcagg gaatttaagt tcagcttgag gcaggatgat ttctggttcc
    12001 acccactttt cttctggaat aggtggaaga ttttgaacag cttcctctgt cagaatttca
    12061 cccgtttcca tatcaacagg aggcaaatcg agtaaggctt tttcagtctc ttcttgttct
    12121 aatctagcct ctttctcagc cttttggcga gctttttctt cttgtttgac aaagcgttcc
    12181 tcttttcgac gctcgtgccc ttcccaccat ttggcaaagc ctctactgaa aaattcagca
    12241 atatcgtaaa cagaccaagg gctgactagg agagaaccca ctaaaatcaa gatagaacca
    12301 ataaagtaag ttccgatatt tgaaaagaga aaggctgttg gaatataaag agcgaccccg
    12361 atcaagcccc ctccagcaaa gctagtcgtt cgaaaaccag tcagatctgt cacaacctga
    12421 gccatggtcc cttttagaac ggacttgtcc aaaccatatt tccaaaccaa gtaggcctca
    12481 aaaatcaaga gtaagccagc aaatatggtg aaaaagccag ataagagtcc ttcctgtttt
    12541 cgtatccact tgaaaaagaa gagatagatt aataggccga atatcgccag ataagctagg
    12601 ctacccacta gcaagcgaat taaattataa agggttatac ctgcagcccc taatttgaag
    12661 gctgcgaaaa tcaataaaat cgcaattcct aacgaaatca acattcgttg aatcgcttct
    12721 tttctttcca gttctgcttt agacggtctc cgtcttgttg tacttgtatt cttgtttgcc
    12781 attcttctat tataccatat ttcacaggca tttcgggaag agaaaaagac tgcaccaaac
    12841 ggtccaatct tttcattttt ctatttttta tgcttgtggt ttgcgtaggt aaccataaac
    12901 cacaccactt acgattgctc ctaccaagac agaaacgagg taaaggagag catttgaagt
    12961 aagggcgata acgaagattc ctccgtgtgg cgccatgagt ttgataccag taagaccaac
    13021 gagtccacct gctactgctg aaccaaggat gaagcttgga atcgcacgag ctgggtcagc
    13081 ggcaccaaat ggaatcgctc cctcagtgat aaatgacaag cccatgatga tgtttgtcaa
    13141 accagagtta cgttcttcct tagtaaattt atctttgaaa agaagagttg cgacaaagat
    13201 tgcaagtggt ggcaccattc ctccagccat aactgctgcc atggctacag aaccacctga
    13261 agaaacagtt gctgcaagcg tacctgtacc aaagacataa gctgctttat taactggtcc
    13321 acccatgtca acagccatca ttccaccaag gacgatacca agaaggacag ctgaacctcc
    13381 tccaagaccg cctaggaagt cattcatagc agtgttgatt gctgccattg ggatattcac
    13441 agctagcata acaaatcctg tcaagattgt tccaagaagt ggcaatagaa ggattgattt
    13501 agcaccttcg agtgaacgag gaactttaac gtatttcttg atggcaagaa ccaaggcacc
    13561 tgcgataaat ccaccaacaa gggcacctag gaaaccagat gagacacctg caagagttga
    13621 agttgcttca ccacctgcgg cataaggaat tttaccaaag gcaaaacctt ctttggcaat
    13681 agcaccagcc acgaaacctg ctaccaaacc tggtttttca gcaatagagt aggcaacata
    13741 acccgcaaag actggaagca tcaaaccaaa ggcagctcca ccaattttca tgaacataga
    13801 agctaactca tggtaagaac caagattgcc aaggttttca tttggaacac tcaaagcacc
    13861 gtcaatcaag aaggcaaggg caatcatgat accaccaccg ataacgaatg gtaacatttg
    13921 agatacacca ctcatcaagt gtttgtagaa ggcaccacca aggctttgtt tttcgttaga
    13981 ggctgttgcg actttggcac cattagcggc acggtagact tccgcatctc ctgaaatagc
    14041 caagttgatc aattcttctg tcttacggat accgtcagca actggacgat tgatcaaagg
    14101 tttgccatcg aaacgatcca tttcaacggc cttgtctgct gcaatgataa tagctttagc
    14161 cttacggata tcttctgcag ttagttgatt tccaacaccg ctagcaccgt tggtttcgac
    14221 cttgatacca acccccattt cagcagctac tttttgaagg gcttcttggg ccatgtaagt
    14281 gtgggcaata cctgttgtac aagctgtaac agctacgata aagtcaccag agtcattagc
    14341 aggtgcttga acaagttcct cagttttttc tgaagcttgg tcaaaaagtt cgataacttg
    14401 gtctgcagat gttgcttgac gaagtttgtc tgcaaaaccg tctttcatca agtattgaga
    14461 caattctgtc aatgctgcca agtgagtatc attggcacct tctggagctg caatcatgaa
    14521 gaagaggtca gttgcctgcc catccaaact ctcatagtca acacccttgt ttgacttagc
    14581 aaagagaact gtcgcttctt tgacagcagc gtttttgctg tgaggcatag cgattccatc
    14641 acccaaacca gtagaagtta aagcttcacg cgccaaaatg ccttctttaa aggtttcaaa
    14701 atctgtcaca taaccgtggc ctgttaggct tttaatcatc tcttcaatga cagcagtctt
    14761 ttcagttgcc tgcaaatcca gcaacatgac atcttttctc aataaatctt gaattttcat
    14821 cgtttttcta cctcaacttt tccatatgtt tctttaataa attccgccgt tgccaagtca
    14881 tctgagaagg tagttgccgt tccgcaagcc actccccatt tgaaggcttc tactgcgtct
    14941 tttgatttga caaattcacc tgtgaatcca gcaaccatag aatcaccagc tccaactgaa
    15001 tttttgactg ttcctttgat tggtttagcg aagtaagctc cctcagatgt gacaagaagg
    15061 gcaccatcac cagccataga gataataaca ttttgagcac ccttagccag taactcacga
    15121 gcgtatttct caatttcatc taaactttcg agtttaaccc caaaaatcgc tccaagttca
    15181 tgattatttg gttttacaag aagaggctgg taatccaaac tatcaattaa ggtctgtcct
    15241 tcaaagtcac agaccacttg cgcaccagtc tggcgcgtca aggaaatcaa atccttatag
    15301 ataacattgc ctagattttt agcacttgaa cctgcaaaga caactgtatc ttctgctgtc
    15361 agactagata aaatagcttt caattcttct agcttaaccg gttcaacagt tggacccgtt
    15421 ccgttgattt ctgtttcttg gtctgctttg attttaacat tgatacgagt atcttctgcc
    15481 acctggacaa aacgtgtctc gatttcttcc tctgctaaag tatctgtgat aaatttacca
    15541 gtaaagccac cgataaatcc cgtcgctgta tttgatatat tcaaacgttt caagacacgg
    15601 ctgacattga ttcctttccc accagcaaac ttatcatcac tgtccatacg atttacacta
    15661 ccaactttga cttggtccaa acgaacgata tagtcaatgg atggattgag tgtgactgta
    15721 taaatcatac ttctattacc tccgttttct ccttaataac ctgcaagagc tcatgccctt
    15781 gactagtgat aacgatagcg cgtttgagtg gggctacctt ggcaaagcaa gtttgtccaa
    15841 tttttgacga atccaccaag aggtaggtct gcttggcatt ctccaaaata gctcttttca
    15901 cagctccctc ctccatatca ggagtcgtat aatagccatc gtcaacacca ttcattccga
    15961 taaaggcacg gtcaaagtgc aattggttaa tctggttaag agcaacgccc ccgatactag
    16021 catctgtcgc cgtcttgacg tttcctccaa ccatgacagt tggaatctgc ttttcaacca
    16081 actgagcggc atggtgaatg gagttggtca caactgtaac attcttattg accaattcat
    16141 gaatcaaaaa agcagttgtt gttccagcat cgataaagat gacatctttt tctttaatga
    16201 gagaggctgc tttctgagcc agcaatttct tttcttgaag gtttttgaca gatttttctt
    16261 gaatggtttc ttcttcctgt aaggagtggg ggagttctgc tccaccatgc acacgacgaa
    16321 gcttattttc cgcttccaac tcatccaagt ctcttcgaac cgttgattct gacgtttcta
    16381 gcaaactaac taatttttct agagaaacta catgatgttg atttaactcc tctagaatca
    16441 gttgtttacg ttctgttttt aacactgaat cacctcctgt tatcgtttac actattcatt
    16501 ctaccatact ttatttcgaa gtcaagcatt ttttatcatt ttctttcaaa atctatcatt
    16561 tttcttattt ctagaatttt tattgcaaga taagagcctt tatggtagac tatttgagta
    16621 agtattggaa gattactcaa gaggcttaag aggccgtgtt ggaaacgcgg taggcgtgta
    16681 atagcgtgcg tgggttcgaa tcccatgtct tccgtcgaaa aaagattatt tttaggatgc
    16741 aacaaatgtt gtatcctttt ttaaaatagg gtctgtttgt gactcccttt ttagcaaaag
    16801 aatgcaaagg aataccaaag ataaaaataa aaaacgttga tttaacaacg ttttaccaag
    16861 gaatgcaaaa gaatgcaaag gaataatgga gccggtggga gtcgaaccca cgtccaaaca
    16921 cctgccaaca tatttgtcta caaccatagg ttatgtatta ttttaacagc ccctcgacac
    16981 ataactcaag tctagaaact gcgagtctat caatctctta tcaagccgct agacaaggct
    17041 taatcgtatc tcgctaataa taagacctgt cattgaacac gagcaatcca aatcgggtca
    17101 cgcctgctgg tttttaggca gctagagcgt aagaagtgtt attttttgca gttatattta
    17161 actgagcgtt tacgtcgcca cacgagtcgc aaaatatgcc tcataatgcc tgtcgaatcc
    17221 gtaacgaccc caaaagacaa taaaaccatt ataccttatc taactcaaaa atgcaaaaag
    17281 aaatcacata cctaaaaaag atactattcg agaaatttag caaactggaa gactaactac
    17341 aactttctca gtgcataact ttacgattgt aaatagagct tacgaaatcc aattaacaca
    17401 tacctaagat gaagctatct gttttgaaga aattcacgaa gagaattatt ctaaaatact
    17461 ttcagatgag aattttcgta ctctctttat tttaattcat ttgagtttaa aaactataaa
    17521 atcaatcctt atattattcg gactactttt cacttattgc accaaaatat agtaaaatga
    17581 aataagaata ggacgaatag atcaggacag tcaaatcgat ttctaacaat gttttagaat
    17641 tagaggtgta ctattctagt ttcaatatac tataaatagg tttcattcga actttaatag
    17701 actatgaaaa ccagtggaac ttaccctgac acggaattcc actggttttt tcgattttta
    17761 tcagattaac ttctactatt cttagctgtg aaaattagtt taagacttta acttattttc
    17821 agtcttctaa tctaaaggcc acttccagta aagaaaaatc agggttctcc tgacttttac
    17881 ttagctaatt ctctttctcg ttctttcatt attttatgat tttcatacaa acgggataag
    17941 aacttagaaa tttctttcaa gatagaatag gttggcactg cgacaatcat tccaactaca
    18001 ccataaatat tgcttgacaa caaaagtaaa actaaaatcg tgattggatg aaccttcata
    18061 acacttccta cgattcgagg atataagata ttgccatcta cctgctgaac aacaagcata
    18121 taaatcactg caatcagcag tctatgggga tcagtgaata tatttgcgat gatcatagga
    18181 atcaaaccaa tacttggccc cacataagga attaaattgg ctacaccaga aaaaatggca
    18241 aaaactaaag catattttaa accaataata ctatagccaa tataagctaa acaacctata
    18301 atgattgcgt caatcgaaac tccactaata tagcgagcaa tcgtcgcatt taaattcttt
    18361 aataagcctg caatatgcaa gcgatccctc tttagaatcg ttctttcaag catgggcaag
    18421 aatttatgtc catctaataa gaaataaacc aaaaaaactg gagtcataat caaaatcaaa
    18481 acagtactga taagagctga caagacgctc cccacactat ttgatacgct atttaggata
    18541 ttttgaagaa tatcaacata ggataagttt aactgctgaa ttgtagcttc tacatccaaa
    18601 ttctggagcg caggataatt agataagtct atgattaagt cttgtactcg actataaata
    18661 gtttgactag atataatcaa actagataac tgattaatca aaataggtaa gagatagaca
    18721 acacctatga ccattcccca gaccaaagta cacaaggtaa ttaaaatacc aagcaaacga
    18781 ttgagtttac agactttatt taagaaagta acaatagggt ttgtcaaata ataaagaaag
    18841 ccccctaata aaaatggaat cataattgta ttaagcacgc taacaaaagg gttaatcaaa
    18901 gaccccatct gtctccatag gtaaaagatg atggttaaga gtaaaatttc tgtggtccaa
    18961 aaaaataatt tatttctacg aaacatgagt tacctccctc actttatttt accatatttt
    19021 caaaaagctt aacagatgaa ttattaaagc aagaatattt tttttcttta tgatagaata
    19081 agactactat gaaaaaaata tttttaactt tgttaactgt ctctctttta gggggtgctt
    19141 ctactgctgt tgctcaagat tttaccattg ccgctaaaca tgcgattgct gttgaggcaa
    19201 atactggtaa aattctctat gagaaggatg caacgcaacc tgtcgaaatt gcttccataa
    19261 caaaattgat tactgtttat ctggtctatg aagctttgga aaacggaagt attaccctct
    19321 ccactcctgt agatatttct gattatcctt atcaattgac gacaaattct gaagccagta
    19381 atattcctat ggaggcccgt aattatactg tcgaagagtt gcttgaagca actctggtat
    19441 ctagtgccaa cagcgccgct attgccctag ctgagaaaat tgctggctca gaaaaagatt
    19501 tcgtcgatat gatgcgggca aaactcttgg aatggggaat tcaggatgcc actgttgtca
    19561 atacgacagg tcttaacaat gaaactctag gggataacat ttacccaggt tctaaaaaag
    19621 atgaggaaaa taagcttagt gcttatgatg tcgctatcgt tgctcgcaac ctcatcaaaa
    19681 aatacccaca agtcttagaa atcaccaaaa aaccttcttc tacttttgct gggatgacaa
    19741 tcacttcaac caactacatg ttagaaggta tgcctgctta ccgtggtggt tttgatgggc
    19801 taaaaacagg aacaacagat aaggctggag agtcttttgt tggtactact gtcgaaaaag
    19861 gcatgagagt catcacagtt gttttaaatg cagatcatca agacaataat ccttacgctc
    19921 gatttacagc tacatcttcc ctaatggatt atatttcttc tacatttaca cttcgcaaaa
    19981 tcgttcaaca aggcgatgcc tatcaagata gcaaagcccc tgtacaagat ggaaaagaag
    20041 atacagtaac tgcagtggct ccagaggata tctatctaat cgaacagatt gggaatcaat
    20101 cttcccaatc tgttcaattc acacctgatt ccaaagcaat cccagcacca cttgaagcta
    20161 gaacagtggt tggccatttg acttatgaag acaaggactt gattggtcaa ggttacatca
    20221 ccacagagcg ccctagtttc gaaatggtag cagacaagaa aattgaaaaa gccttcttct
    20281 taaaagtttg gtggaatcag tttgtccgct ttgttaacga gaaattataa aaaatcgcga
    20341 ttttaaaccg cgattttttg atacaagttc atcttcaaaa tccttgattt tgagtaaatc
    20401 taatactcaa aatcaaagaa caaactagga agctagccgc aggttgctca aaacactgtt
    20461 ttgaggttgt agatgaaact gacgaagtca gtaaccatac atacggtaag gcgatgctga
    20521 cgtggcttga agagattttc gaagagtata aaatcaaatt ttatccaact gatccctcca
    20581 tttcatagct aatcaagcgg ttcagctcaa ctgcgtattc cattggaagt tcttttgtaa
    20641 agggttctac aaatcccatg acaatcattt cagttgcctc agattctgac aatccacggc
    20701 tcatgagata atacaattgc tcttctgaaa tcttagatac tttggcttcg tgttccaaag
    20761 ccacttgcga gttgtgaatt tcattaaatg gaatagtatc tgatgctgac aagtcatcca
    20821 tgataatggt atcacattca atgtgggaaa cagatttctt agagttcttg ttaaaggtga
    20881 cttgtccacg gtagtcaacc tttcctccac ctttagcgat ggatttagac acaatagacg
    20941 agctggtatg tggagcattg tgaatcatct tagcacccgt gtcttggtgt tgccctgcat
    21001 tagcaaaggc gatagagagc atggtaccac gcgctccttc tccatcaagg taaacagatg
    21061 gatatttcat agtcgttttg gcacccaagt ttccatcaat ccactcaaca gtggcatcct
    21121 tttgagcctt agcacgcttt gttaccaagt tatagacgtt atcagaccag ttttggatag
    21181 ttgtataacg catataagct ccgtccaaag caaaaatttc tacaatggca gcgtgtaagc
    21241 tattgcttga atatgttggt gctgtacatc cttctacgta gtggacgctt gctccctcat
    21301 caacgataat caaggtacgt tcgaactgac ctatattttc gttattgata cggaaataag
    21361 tttgaagtgg aatatctacc ttgacacctt ttggcacgta gataaaagtt ccacccgacc
    21421 atactgctga gttgagggct gccaacttgt tatctgtcgg cggtaccaac ttcgcaaagt
    21481 attgtttaaa taagtctggg tattccttga gtgcggaatc tgtatctgta aagataatac
    21541 ctaatttttg gaactcttcc ttcatgttgt ggtaaaccac ttctgactcg tactgggcag
    21601 aagcccctgc taaataagca cgttcagctt ctggaatccc gatacgttca aaggtttctt
    21661 taatcttttc aggtacatca tcccaagaac gggctggttt gtcagatggt ttttggtagt
    21721 agattaagtc atcaaagtca atctctgaca agtctgctcc ccaagtttgc atgggcattt
    21781 ttttgaaggt ttcataagac ttcaaacgga actccaacat ccactcaggc tcacccttag
    21841 cagcagataa ttcacgaata acaccttcgt tgagtccttt tcctgtcgat aagacaggct
    21901 ctacatcgtc atggaaacca aatttatatt caccaaggtc aattggtttt ggttctactc
    21961 tttcttcagc catagtatcc tttctttctt catttctaat aattcataag acaaaagaaa
    22021 cttgtcttac tgtttttctt gattttcaat tgttttctta agggcattcc aagctagggt
    22081 tgcacacttg attctttgag ggaatttggc aacacctgac aagaatgccg cgtctccaag
    22141 ttggccttga cgctcatctt tttgcccttg aaccatttca gaaaaaatag tcgccagttc
    22201 taaaatttct tgtttggttt ttcctaaaac ggcatctgtc atcatactag cagaagcagt
    22261 tgaaatcgtg catcctgaat ttagaaaagc aatatcttcc aaacggtcct ctgcatcaaa
    22321 cttgacagag aggttgatga catccccaca agtcggattg ttgagactgg tttgctcagc
    22381 atcttctaac ttcccttggt gatgtggatt tttcgaatgg tctgctacca ctgccatata
    22441 aaggctatct agtttagaaa gtgccattga aaaactcctt tgtcttttgt agggcatcga
    22501 ctagtttgtc gcaatctgcc ttggtattgt agatataaaa acttgcacga gctgttgctg
    22561 ggacttccaa atactgaagc aagggttgcg cacaatggtg accagcacga acagccactc
    22621 cttcataatc cagagccgtc gcaagatcgt gaggatggag atcacctagg ttaaaggcaa
    22681 taacacccga acgttgagcc aaatcctgag aaccgtaaat ggtcaatccc tcaattgcct
    22741 gcagttttgg atagacgtac gcaatcaatt cctgttcatg agcttcaacg gcatccatac
    22801 caatcttttc cagataatca actgcagtcg caagtccaat agctcctgcc atatttggcg
    22861 ttccagcctc aaatttccaa ggcaattcct tccaactagc aaattgctcg tagacaaaat
    22921 caatcatctc gccgccaaat tctactggag acatttgctc aagatacttt tctttgccgt
    22981 aaaggacacc gataccagtc ggaccagcca tcttgtgacc cgaaaaggcg aaaaagtcca
    23041 gatccaagtc ctggacatca atcttcatat gaggtgtaga ttgagcacca tccactacca
    23101 taattgcccc aacttggtgg gctaattgag tgatttcctt gatcggattg accacaccaa
    23161 gaacattgga ggcatgagct agggaaacaa atttaacctt atcagtcaat ttagctcgca
    23221 aatcctccat atccaaggca ccgtctttaa gatagacata gacaagctct gctccagtct
    23281 ttcgacaagc ttcctgccat ggaatgatat tagaatggtg ttccattact gaaatcaaga
    23341 cccggtctcc ctcagcgaga atttcctcag caaagcgtgc cacccagtta aggctggttg
    23401 tcgttcctct ggtaaagaga acttcctttg tagagcctgc attaataaac ttacgaatgg
    23461 tttcacgagc agcttcataa gaagctgtcg ctcgttccgc taaggtatgg acaccacggt
    23521 gaacattggc attgtcctgc tcatagtaac tgttaatagc tttcagaact actagtggtt
    23581 tttgtgtcgt cgcagcattg tccagataga ccagaggttc atcattgaca atctgatcta
    23641 aaattggaaa atccttgcga atcgcttcta catctaacat aggcttcccc ttagcgtttt
    23701 gacaatttct cttcgatagt tgcaatcatt tcatcacgaa cttccttgac tggaatctcc
    23761 acgataacag atccaaggaa accacgaaca accaaacgct ctgcagttgc cttatccaat
    23821 ccacgactca tgaggtaata catgtcttct ggatcaactt gtccgataga cgctgcgtgt
    23881 cctgcagtga catcattttc atcaatcaaa agaattgggt tagcatctga acgcgcttgg
    23941 tctgaaagca tgagaacacg gctctcttgt tgcgcatctg ctcccttagc acccttgatg
    24001 atgtggccga taccattgaa agtcaaagtt gctttttcaa ggataacccc atgttgtagg
    24061 atatttccga tagagttgca gccatagtta gttacacgag tatcaatccc ttgtacctga
    24121 cgaccacttg aaagagctac aaccttgagg tcagcatggc taccattacc aatcaagtca
    24181 ctatcaaaat cagcaacgac atttccttcg ttcatgacac cgatagccca gtcaatactt
    24241 gcatcgttgc ctaatttacc acgacggcta atgtaggcag tgacgttttc acctagacgg
    24301 tcgatagcag caaacttgac ttgcgcacca gaacgtgcaa tcacttccac tgtgatattg
    24361 gcagttactt tgtcacttcc ttcaccgcgt gactctaaac gctccagata actaatctta
    24421 gaatttttac cagcgataat cataatatgc ttgttaaacg gcacattgct atcgctatct
    24481 tggtagaaaa ttccttcaat tggctctgtg atttctacgt tatctggaat atagagtaca
    24541 gcaccactgt taaagtaagc tgtgtggtaa gccgccaact tgtcatcatc atacttaaca
    24601 gatgacatga agaattcttc gatcagctct ggaatttctt ctaaagctga gtgaaagtct
    24661 gtgaagacaa caccctgttc agctaactca actggagttt gttcgaaaac agtttgagtt
    24721 cctacttgca ccaacttcaa gtgatgatct aaagctgtga aatctggaac atttgctgat
    24781 ggctcatttt ctgtaatcgt tccatcaccc agattccaac ggtggaattt gacacgctca
    24841 ataactggta attccaaagt ctcaatcttg tcaaaagctt tttgacggag atcagccaac
    24901 cagcttggtt cagcgtgcat ttctgaaaaa agtttaatat tttctctagt catttacttc
    24961 tcctaaaaga tacgagggaa ttacaattct tccttgtagt cgtagccaag ttcttcagct
    25021 agttttgcgt atccttcacg ttccaaacgc gcagccaatt ctggaccacc agaaaggaca
    25081 acacgacctt ccatcatcac gtgtaccaca tcaggtgtga tatagttcaa aagacgttgg
    25141 tagtgagtga tgatcatagc accaaaacct tcaccacgca tggcattgac acctttagac
    25201 acaactttaa gagcgtcaat atcaagacct gagtcaatct cgtccaaaag agcaaatgtt
    25261 ggctccaaca tcaaaagttg aagaatttca ttgcgttttt tctcaccacc agagaagcct
    25321 tcgttgaggt aacgctctgc catttcttct ttcatgttga gcaattccat tttttcatct
    25381 agcttagtaa taaactcacg aactgaaatc ttctcatcat cttctttacc cgcattcata
    25441 gcggcacgaa gaaactcagc attggtaatt ccagggattt ctgatgggta ttgcatagca
    25501 aggaaaagtc ccatacgcgc acgctcatcc acttccaact caaggatgtt tacgccatca
    25561 aacaaaactt cacctttagt tacttcatag tttggatttc ccatgatagc ggcagaaaga
    25621 gtcgatttac ctgtaccatt tggtcccatg atagcggcaa tttctcctgt tttcagggtc
    25681 aggttaaccc cttttaaaat ttcttttcct tcaatctcaa cgtgaagatc tttgatctct
    25741 attactgaca tgatagttcc tttctttttc aaaactttta cagtacttac tagaaaaacg
    25801 tctgatttcc ccagaaatag agcaaaaatt ctataaatat acttttctag tataacaaaa
    25861 aaaagcctaa aaggctttga ttttgtctgg aagctgaggg ctagtctttc ctattaaaat
    25921 gctgatcgat gacatcaaca attttaccca tcacataact gactcggaaa tttctaaaga
    25981 gtaaaattgc ccaaaaggct gccataatat agcggccagt catccaggct tcattgaaaa
    26041 aataggtctc agcagctgta aatagcgcca taataataaa ttgttgttta ttcataaact
    26101 tattgtatca tgaaatcttt ctttagtctt cctctacctt cactttatca gccaaaaatt
    26161 caaatccttc tggaatcagg ctttcttcta cttctttttc agtttgagaa gatttggctt
    26221 tggctgaaaa ggctgcgcga acttctttcc attcctccat ggaaatagct aaaatctcag
    26281 gtgaaaaacc tgccgcctga ctgaggatat taccaaacat ggtattgaga ttgtctcgtt
    26341 tcatagtttg accagcattg aagttagact caaaagcaag aatagcatgg tgttcattgg
    26401 cagcaaccgg ttgagaacca actagcagag ccttgtccgg cccacctaga ctttcaatta
    26461 cctctcccca ggcattctgc aaacgaatta gattttgacg tgctaaatca ggattttcga
    26521 cggcctcttg taagatagat tgcactttat tgcgatcgac acgatagact gttttgcccg
    26581 tagctggtcg actaggagct ggtgcaactt gtttaggaac cgcacctgca ttagaaagct
    26641 cttgtttgag acgggcaact tcctgtctca gcgtagcaat ttcattttca accgctcctg
    26701 atagagctgg ttcgggcttg atttccgcca aacggacggt catcatttca gcataaatct
    26761 tgggctgcaa actagactta atatctgcta aattcactgt tgctaagcga atcatttcaa
    26821 acagattttt ttgaggaagt gccaaatttt ctacaaagac tgaactatga tgagtatttt
    26881 ctccccctgt ttgaacaatt aacaagtctc ttaaatagtg caaaagatcg gtcacaaaac
    26941 gagtcatgct cttaccattg tcaaaaagaa gattcaagca agacaaagct ttgggaacat
    27001 cctgttgaga caaggccgcc acataatcat ccaaggctga taggctaatg gtgccagtaa
    27061 tttcttcaga gatagcagtc gtcagctcat ttccctgtgt caaactcagg gcttgatcca
    27121 aaatagacaa ggcgtcccgc attccacctt ccgcccgtct ggcaatgatt tccacagcct
    27181 ctggttcaga actgatattt tctttttcta agatatagtg aatatgttcc ttaatatcct
    27241 gtgtcttaat tgatttaaac tcaaaacgtt gcacacggga tagaatagta gcaggaatct
    27301 tgtgcaattc agtagtggcc aaaataaaga ctacattctg tgttggttct tccagcgtct
    27361 ttaggagggc attaaaagcc cctgtagaca gcatgtgaac ctcatctatg atataaacct
    27421 tataacgagc aaggctaggc gcataggtag atttatcacg aatttcgcga atttcatcta
    27481 ccccattatt agaagctgca tccatttcaa tgacatcttc taaactaccg tccgtcactg
    27541 cttgacaaat atagcagtta ttgcaaggtt cgccacccac ttgattggga cagttcatag
    27601 ccttggcaaa gattttagca acactggttt ttcccgttcc acgaggacca gaaaaaagat
    27661 aagcgtgact tattttctct tgctccaccg cttgtttaag agtcttagcc acaacttctt
    27721 gaccaactaa ctgggagaag ttttgacttc tatattttcg ataaagtgct tgatacatta
    27781 agatttttcc tcaaacatcg taaagtccca tgctgtcttt tcaagcaaaa tagcgacaaa
    27841 ttgttccaaa taatctcgat ccatagcatc gtaatcctca atctctgaag aatccagatc
    27901 cagaactcca agtaactgac cattcttcat catcggcacc acaatttcac ttttagctag
    27961 actatcacaa gaaatatagt tgagataggt cgtcacatct ccaacaataa cagtttcctg
    28021 aaagtgagct gcctcaccac aaacaccctt gcctagtgca atacggatgc aggaaacacc
    28081 tccttggaag gggcctaaaa ccaattcctt tccatcgaac aaataaaagc ctgcaaatac
    28141 ggtattagga aaacgtgatt ttatgagagc actggcgttg gaaagattag ccaaaacatt
    28201 ggtttcgcct tccaatagga aggacaattc ttcatttaac atttgataac gtgattgttt
    28261 ttctgatttt aacatagaac tattatatca aaaaaggagt agagacaaaa gaaaaatccc
    28321 ttgtttagta aacaaaggat tttgggctct ataatatttg tagtgggtaa atcccctatg
    28381 gatattatgg agcctatttt tgtgtagaaa aaaagtccca tatgacctat aatgaaaagc
    28441 gat
//
LOCUS       DAVKBC010000025        27145 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVKBC010000025 DAVKBC010000000
VERSION     DAVKBC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27145
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.025"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(432..512)
                     /locus_tag="VWX64_001266"
                     /pseudo
     CDS             complement(432..512)
                     /locus_tag="VWX64_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            628..1521
                     /locus_tag="VWX64_001267"
     CDS             628..1521
                     /locus_tag="VWX64_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190736.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            1518..2717
                     /locus_tag="VWX64_001268"
     CDS             1518..2717
                     /locus_tag="VWX64_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190737.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMTKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(3070..3837)
                     /locus_tag="VWX64_001269"
     CDS             complement(3070..3837)
                     /locus_tag="VWX64_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190738.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(3854..4549)
                     /locus_tag="VWX64_001270"
     CDS             complement(3854..4549)
                     /locus_tag="VWX64_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190739.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(4554..4919)
                     /locus_tag="VWX64_001271"
     CDS             complement(4554..4919)
                     /locus_tag="VWX64_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9190740.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            5059..5532
                     /gene="nrdR"
                     /locus_tag="VWX64_001272"
     CDS             5059..5532
                     /gene="nrdR"
                     /locus_tag="VWX64_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU9190741.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            5533..6702
                     /locus_tag="VWX64_001273"
     CDS             5533..6702
                     /locus_tag="VWX64_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU9190742.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            6703..7599
                     /gene="dnaI"
                     /locus_tag="VWX64_001274"
     CDS             6703..7599
                     /gene="dnaI"
                     /locus_tag="VWX64_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU9190743.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKFSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            7596..8309
                     /locus_tag="VWX64_001275"
     CDS             7596..8309
                     /locus_tag="VWX64_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU9190744.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            8323..9633
                     /gene="der"
                     /locus_tag="VWX64_001276"
     CDS             8323..9633
                     /gene="der"
                     /locus_tag="VWX64_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU9190745.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRR"
     gene            9724..10059
                     /locus_tag="VWX64_001277"
     CDS             9724..10059
                     /locus_tag="VWX64_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190746.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            10199..10534
                     /locus_tag="VWX64_001278"
     CDS             10199..10534
                     /locus_tag="VWX64_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190747.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     SLFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            10719..11510
                     /locus_tag="VWX64_001279"
     CDS             10719..11510
                     /locus_tag="VWX64_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190748.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIVTYFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFFKIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            11503..12144
                     /locus_tag="VWX64_001280"
     CDS             11503..12144
                     /locus_tag="VWX64_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190749.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            12148..12798
                     /locus_tag="VWX64_001281"
     CDS             12148..12798
                     /locus_tag="VWX64_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9190750.1"
                     /translation="MKLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            12809..13096
                     /locus_tag="VWX64_001282"
     CDS             12809..13096
                     /locus_tag="VWX64_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190751.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWIAFFFLPWGSPILGGKIDLFS
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFILFAILPILGN"
     gene            13242..15755
                     /gene="secA"
                     /locus_tag="VWX64_001283"
     CDS             13242..15755
                     /gene="secA"
                     /locus_tag="VWX64_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU9190752.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            15836..16867
                     /locus_tag="VWX64_001284"
     CDS             15836..16867
                     /locus_tag="VWX64_001284"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9190753.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            16869..17900
                     /locus_tag="VWX64_001285"
     CDS             16869..17900
                     /locus_tag="VWX64_001285"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9190754.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            17939..18307
                     /locus_tag="VWX64_001286"
     CDS             17939..18307
                     /locus_tag="VWX64_001286"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU9190755.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            18297..19400
                     /locus_tag="VWX64_001287"
     CDS             18297..19400
                     /locus_tag="VWX64_001287"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU9190756.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            19419..21434
                     /gene="recG"
                     /locus_tag="VWX64_001288"
     CDS             19419..21434
                     /gene="recG"
                     /locus_tag="VWX64_001288"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU9190757.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            21750..22730
                     /locus_tag="VWX64_001289"
     CDS             21750..22730
                     /locus_tag="VWX64_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU9190758.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFYDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            23490..23717
                     /locus_tag="VWX64_001290"
     CDS             23490..23717
                     /locus_tag="VWX64_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190759.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            24005..26887
                     /gene="nanA"
                     /locus_tag="VWX64_001291"
     CDS             24005..26887
                     /gene="nanA"
                     /locus_tag="VWX64_001291"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU9190760.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGVIG
                     LEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESM
                     HNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTK
                     EDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         8200 a         4956 c         6065 g         7924 t
ORIGIN      
        1 gatttgactg tcccgatcta tttgtcctgt ttttatttca ttttattata taatccttag
       61 aaaacatatc ggacaagcgg ttgaattctg ttccgtccat tagtagataa aggattactc
      121 cttcttgaaa tgacagatga acttgtttct tataaaaatg ttgtctgaaa ctattcgctt
      181 ttttccagaa attttagagg aagaaaactt tatgaggaaa aaggagttac tcaaataaca
      241 attcaggatt aaaaatagac agttgaggag cggaaggtat aaattaagtt tgctactgta
      301 taatggattt atcactaata ctcttcgaaa atctcttcaa accacgtcag cttcgccttg
      361 ccgtagatat agttactgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag
      421 ctgacttcgt cagttttatc tgcaacctca aagctgtact ttgagcagcc tacggctagc
      481 ttcctagttt gctctttgct tttcattgag tataaaagtg ctccaggcca tattttacac
      541 agcaatagtc ttctaaaaat ggacaaaaac attgtaaagg ctatcaaaaa ggagtataat
      601 gagtgcaaga aatttcggag gtgaaagatg ctagaagtaa gaagtctaga gaaaagtttt
      661 ggctccaagc aagttttgtt tggtattgac tttcaagcgc gaccaggtcg tattttggga
      721 ctagtcggaa aaaatggtgc tggaaaaaca acgattttcc atagtatttt gaaattccta
      781 gaatatcagg gagaaatcgg tctggatggt caggatattc gtcaggagac ctatgctcgg
      841 attggttatc tgcctgaaga acgcagtctc atgcctaaat tgacagttct tgaacaagtt
      901 cgctacttgg cgactctaaa aggcatggat gccaaagaag tcaaagaaaa actccctcaa
      961 tggatgaaga ggttggaagt gaaaggaaag ctgacagata aaatcaagag tctgtcaaaa
     1021 ggaaatcagc agaagattca gctcattatt actctgattc atgaaccaga cctgattatc
     1081 ttggatgagc cttttagtgg attggaccca gttaatacag aattgctcaa acaagtcatt
     1141 tttcaggaaa aagagcgcgg agcaaccatt atcttttctg accatgtcat gaccaatgtt
     1201 gaggaacttt gtgacgatat tctgatgatc cgagatggcc gtgtggtctt gcacggacca
     1261 gttcaggatg tccgcaatca atacgggaaa acgcgtctct ttgtttcaag tgaacgaagc
     1321 aaggaagaat tggaaaatct tcctcatgtc aaacaggtga gcttgaccaa acaaggcagt
     1381 tggaaattga ttttggagga tgagagcgct ggaagggaac tcttcccaat cttgactcaa
     1441 ggtcaatata tcgcaacatt tgaccaacaa gcgccaacta tcgatgaaat ctttaaacta
     1501 gaatcaggag tggaagtatg agaaatatgt gggttgtaat caaggaaacc tatcttcgac
     1561 atgtcgagtc atggagtttc ttctttatgg tgatttcgcc gttcctcttt ttaggaatct
     1621 ctgtaggaat tgggcatctc caaggttctt ctatgactaa aaataataaa gtggcagtag
     1681 tgacaacagt gccatctgta gcagaaggac tgaagaatgt aaatggtgtt aacttcgact
     1741 ataaagatga agcaagtgcc aaagaagcaa ttaaagaaga aaaattaaaa ggttatttga
     1801 ccattgatca agaagatagt gttctaaagg cagtttatca tggcgaaaca tcgcttgaaa
     1861 atggaattaa atttgaggtt acaggtacac tcaatgaact gcaaaatcag cttaatcgtt
     1921 caactgcttc cttgtctcaa gagcaggaaa aacgcttagc gcagacaatt caattcacag
     1981 aaaagattga tgaagccaag gaaaataaaa agtttattca aacaattgca gcaggtgcct
     2041 taggattctt tctttatatg attctgatta cctatgcggg tgtaacagct caggaagttg
     2101 ccagtgaaaa aggcaccaaa attatggaag tcgtcttttc tagcataagg gcaagtcact
     2161 atttctatgc gcggatgatg gctctgtttc tagtgatttt aacgcatatt gggatctatg
     2221 ttgtaggtgg tctggctgcc gttttgctct ttaaagattt gccattcttg gctcagtctg
     2281 gtattttgga tcacttggga gatgctatct cactgaatac cttgctcttt attttgatca
     2341 gtcttttcat gtacgtagtc ttggcagcct tcctaggatc tatggtttct cgtcctgagg
     2401 actcagggaa agccttgtcg cctttgatga ttttgattat gggtggtttt tttggagtga
     2461 cagctctagg tgcagctggt gacaatctcc tcttgaagat tggttcttat attcccttta
     2521 tttcgacctt ctttatgccg tttcgaacga ttaatggcta tgcggaggga gcggaagcat
     2581 ggatttcact tgctattaca gtgatttttg cggtggtagc aacaggattt atcggacgca
     2641 tgtatgctag tctcgttctt caaacggatg atttagggat ttggaaaacc tttaaacgtg
     2701 ccttatctta taaatagaag agccttgcga aagcgaggtt tttaaaggtg aaaagggtgg
     2761 aatcacgaac ctaattatgt acacattatg taaacaggtt gcttgaaaac tcaattgtat
     2821 agtgaactga atctggaata ggataatatt acttctaaaa cattcttata aattgatttg
     2881 aattccaaaa tcccatcgtt ccgttcttat ttcattttgc gatatagcga aaggaaataa
     2941 gtcaactcac aaaaaacgca taatatcaag gatttttaac acttgatact atgcgttttc
     3001 taattttaaa gactttttgc ctggtctctt ttgttctatg agtatgttac atatctaggt
     3061 aaaaattatt taaagcaaat taaccttatt tctcaagatg tagtaggttc cgagataaaa
     3121 gatagctatg aatatgagtt ctttaacaat ggctatacct gctcccatat agaaatggtc
     3181 attgagtcct accagtgaat tgacatagaa attagaacta agattgaaga aaagttcaat
     3241 aaatccaatg acgatttgga taccaatgta ggctgcaaca gcgagtgctg tacggtattc
     3301 attgaaaagc tgtccaatgg aaatagccag gtagatgcag aggattcctg aaatggtatt
     3361 tagtaggaag gatatacctg taagaaagat ctgagggaga tgtgtttcta caaatgtaat
     3421 cacataagaa agaggaatcc attctggagc tgttaaagcc agaataataa cagcacttag
     3481 agccaataca gcggtgctaa tcaatgacca gataaaggca ccgattagtt tggctgtgat
     3541 gatatggtgt tcagaaactg gcaaggtcaa agtcagatag ccttgtcggt cgtagacact
     3601 acctttgaag cgtttaataa tcaagaaaat ggttgaaatc gcaagtgtaa gcatcaagcc
     3661 accaaagact gtagctagaa aaagtagcat agtagcctga ctttcttggt aaggtagatt
     3721 tttaaagcct tgtgtctgta ttccgatgag ggcagaaagg actagcacgg ctgcgtagag
     3781 ggctaaatac cacttgttaa catttttaaa ttcgtagtga actaaattcc aaaacataaa
     3841 taatctcctt tgcttaggcc ttaaattcct gacggaagag ttggtcaatg gattcacctg
     3901 actcgtagcg aatatcatct acatttcctt gacggacgac ttttccgtct tttaggaaga
     3961 caatttcatc caagattggc tcgatatcag aaatcaagtg ggtagaaatc aaaacggtag
     4021 aagttggtga gtagttgttg ataatggtat tgaggatata agcacgggct gctggatcca
     4081 ccccaccaat gggttcatcc aaaacataga gacgagcatc acggctcata accaaaatca
     4141 gttgaacctt ttctttgttt ccttttgata gtttcttgag acgactattt tcatcaatgc
     4201 ccaggtctgc aagtagatga tgagcgcgtt caagattgaa atctttatag aaggtcttga
     4261 agtaggttag ggcttctttg accttcattt gctcattgag ataggtcgta tcaggcaaat
     4321 aagctacaac ggccttggtt gctgggcttg ggtccatgtc gttgatgagg acacgtcctt
     4381 gatctggttg taagaggcca ttaattagtt taatcagggt tgtttttcct gagccgtttg
     4441 gcccaagaag gccgacaatt tttccagctg gaatgtcaag agaaacattt tcaagggctg
     4501 gtgttgctcc atatgatttg gatacatttt caaatgctag taatgacata ggcttaaact
     4561 cctttaatat aatcactgac tacgcctggt agttcttctt tttcatagcc aaaatgggtc
     4621 atggaggaaa cgaagtgttc caattcttct tctgataatt gtttgcgtga ctgagcgatt
     4681 agctccttat ccttagtcac aaatcgtcca gttgttcgct tgctgtagac aaatccttct
     4741 cgttcaaggt ctgataaggc tctttggatg gtattgggat tgacaccagc ctcgctagct
     4801 agctccctca cggttggaag ttgttgattg ggttccagtg tatgggaaac aatctgaagc
     4861 ttgattttct ccataatctg taaatagatg ggttttttgt tgtcaaatgt ccaggacatc
     4921 ttagtctcct ttctcttatt cttttgtctt aattaaataa tacaacaaaa caaaaaactt
     4981 gtcaagcaaa aagaagaatt gttttgggaa tcgcttaaaa aatggtataa tgaaaagaaa
     5041 acgataagga gggaaaggat gcgttgtcca aaatgtgggg ctaccaagtc aagtgttatc
     5101 gatagtcgcc aagcagaaga agggaacacc attcgtagaa gacgagagtg cgacgagtgc
     5161 caacaccgtt ttacaaccta cgaacgagta gaagaaagaa ccttagtggt tgttaaaaaa
     5221 gatggcacac gggaacaatt ctccagagat aaaatcttta atgggattat ccgctcagcc
     5281 cagaaacgtc ctgtgtcaag tgatgaaatc aacatggtag tcaatcgtat cgaacagaaa
     5341 ctccgtggtc gaaatgaaaa tgaaattcaa agtgaggaca ttggttcact cgtcatggag
     5401 gagttggctg aattggacga gattacctat gtacgttttg ctagtgtcta tcgtagtttt
     5461 aaggatgtca gtgagttaga gagcttgctc caacaaatca cccagtcctc taaaaagaaa
     5521 aaggaaagat aaatgaagcc aattgaccgt ttttcttatc taaagaataa tcgggtgtcg
     5581 caagatacct catctctggt acagtgctac ctcccgatta tcggtcagga ggcactgagc
     5641 ctttatcttt atacaatcag tttttgggat aatggtagaa aggaatatct tttttcaagt
     5701 atcctcaatc atctcaactt tgggatggat agactgataa aatcattgaa aatcttatct
     5761 gcttttaatc tcttgaccct ctatcaaaag ggggatgttt atcagctagc cctccatgct
     5821 cctctatcta gtcaagactt cttggagcat cctgtttatc gcagactctt agagaaaaag
     5881 attggcgact ctgctgtgga ggatttgaaa gttgaaagtg ctgatggtga agaaatacct
     5941 gtctcactca atcaagtctt tccagaattg gcagaactag gcagtcaaga agaccttggt
     6001 ctcaagaaga aagtggccaa tgattttgac ttggaacatt ttcgccagct gatggctcga
     6061 gatggacttc gttttgcgga tgagcagtcc gatgtcttaa acctctttgc tattgccgag
     6121 gagaagaaat ggacttggtt tgaaacctat caattggcca agtcaacagc tgtttctcag
     6181 gttatttcaa ccaaacgcat gcgtgaaaaa attgctcaaa aaccagtttc ctctgacttt
     6241 agtcttaagg aaacaaccat tatcaaagaa gccaaaagta aaactgccct gcagttcttg
     6301 gcagaaatca agcaaacacg caagggaacc attacccaaa cagaaagaga actcttgcaa
     6361 cagatggctg gcttgggctt gctggacgaa gtcatcaata tcattctttt attgaccttt
     6421 aataaggtcg attcggcaaa tatcaatgag aaatatgcca tgaaggtagc caatgactat
     6481 gcctatcaaa agattcattc ggcagaaaag gcagtcttgc gcatccgtga gcgaggacag
     6541 aaagcaaaaa cacaaaaaca gaatcagact gccccagtaa aaaccaatgt tcctaaatgg
     6601 agtaatcctg aatataagaa tgaaaccagc gaggaaactc gtctggaact agaacgtaag
     6661 aagcaagaac tattagctcg attagaaaaa ggaggagatt agatggaaag tgtcggagac
     6721 gtactcaaac gtcaacccag ccgtttttat tatcaagatt tggtccagaa aatcatgaag
     6781 gaccctgatg ttgcggcttt tatccagcaa gaatccttga ctccagagga attaaatcgc
     6841 agtatctcca agtttaatca gtacatcacc gagcgtgaca agtttctccg tggggatacg
     6901 gattatattg ccaaaggcta caagccgatt ttggttaaga atcatggcta tgcagatgtt
     6961 tcatatgaag aaactcctga gctaatcgcg gctgaaaaag aagcggctat taagaaccgt
     7021 ctcaagttaa tcaatctacc agccagtctc aagaaagcta gtttggctca agttgacttg
     7081 gatgatttgg ggcgcttacc agtttttgaa aagctactag ccttcgtgga gcaatatcca
     7141 gctattcgaa aaggtcttta cttatatgga gactttggtg tgggtaaaag tttcatggtg
     7201 gcggccttag ctcatgattt atcagaaaaa cgtggtgttt catcaactct cctccactat
     7261 cctagctttg tcattgatgt caaaaatgct atcagtgatg gcaatgttaa gaccttggtg
     7321 gatgagatta agttttctga agtcctgatt ttagatgata ttggtgccga gcaatccacc
     7381 gcttgggtgc gtgatgaaat cctgcaggtc attctccaat atcggatgca ggaaaattta
     7441 ccgacctttt tcacctctaa cttcaacttt gaagatttgg agaagcattt cgctaaaggg
     7501 aaaaatggaa atgacgaaac ctgggaagcc agacgtgtca tggaacgcat ccgttatttg
     7561 gctgaggaga ctcgtttaga aggagtaaac cgtcgatgac agaaaccatt aaattgatga
     7621 aggctcatac ttcagtgcgc aggtttaaag agcaagaaat tccccaagta gacttaaatg
     7681 agattttgac agcagcccag atggcatcat cttggaagaa tttccaatcc tactctgtga
     7741 ttgtggtacg aagtcaagag aagaaagatg ccttgtatga attggtacct caagaagcca
     7801 ttcgccagtc tgctgttttc cttctctttg tcggagattt gaaccgagca gaaaagggag
     7861 cccgacttca taccgacacc ttccaacccc aaggtgtgga aggtctcttg attagttcgg
     7921 tcgatgcagc tcttgctgga caaaacgcct tgttggcagc tgaaagcttg ggctatggtg
     7981 gtgtgattat cggtttggtt cgatacaagt ctgaagaagt ggcagagctc tttaacctac
     8041 ctgactacac ctattctgtc tttgggatgg cactgggtgt gccaaatcaa catcatgata
     8101 tgaaaccgag actgccacta gagaatgttg tctttgagga agaataccaa gaacagtcaa
     8161 ctgaggcaat ccaagcttat gaccgtgttc aggctgacta tgctggggcg cgtgcgacca
     8221 caagctggag tcagcgtcta gcagaacagt ttggtcaagc tgaaccaagc tcaactagaa
     8281 aaaatcttga acagaagaaa ttattgtaga aagtgagaaa ttatggccct accaactatt
     8341 gccattgtag gacgtcccaa tgttgggaaa tcaaccctat ttaatcggat cgctggtgag
     8401 cgaatctcca ttgtagaaga tgtcgaagga gtgacacgtg accgtattta tgcaacgggt
     8461 gagtggctca atcgttcttt tagcatgatt gatacaggag gaattgatga tgtcgatgct
     8521 cctttcatgg aacaaatcaa gcaccaggca gaaattgcca tggaagaagc agatgttatc
     8581 gtttttgtcg tgtctggtaa ggaaggaatt actgatgcag acgaatacgt agctcgtaag
     8641 ctttataaga cccacaaacc agttatcctc gcagtcaaca aggtggacaa ccctgagatg
     8701 cgaaatgata tctatgattt ctatgccctc ggtttgggtg aaccactgcc tatctcatct
     8761 gtccatggta tcggtacagg ggatgtacta gatgcgattg tggaaaacct tccaaatgaa
     8821 tatgaagaag aaaatccaga tgtcattaag tttagcttga ttggtcgtcc taacgttgga
     8881 aaatcaagct tgattaatgc tatcttggga gaagaccgtg tcattgccag tcctgttgct
     8941 ggaacaactc gtgacgctat tgatacccac tttacagata cagatggtca agagtttacc
     9001 atgattgata cggctggtat gcgtaagtct ggtaaggttt atgaaaatac tgagaagtac
     9061 tctgtcatgc gtgccatgcg tgctattgac cgttcagatg tggtcttaat ggtcatcaat
     9121 gcggaagagg ggattcgtga atacgacaaa cgtatcgctg gatttgctca tgaagctggt
     9181 aaagggatga ttatcgtggt caacaagtgg gatacgcttg aaaaagataa ccacactatg
     9241 aaaaactggg aagaagatat ccgtgagcag ttccaatacc tgccttacgc accgattatc
     9301 tttgtatcag ctttaaccaa gcaacgtctc cacaaacttc ctgagatgat taagcaaatc
     9361 agcgaaagtc aaaatacacg tattccatca gctgtcttga acgatgtcat catggatgcc
     9421 attgccatca acccaacacc gacagacaaa ggaaaacgtc tcaagatttt ctatgcgacc
     9481 caagtggcaa ccaaaccacc aacctttgtc atctttgtca atgaagaaga actcatgcac
     9541 ttttcttacc tgcgtttctt ggaaaatcaa atccgcaagg cctttgtttt tgagggaaca
     9601 ccgattcatc tcatcgcaag aaaacgcaga taaaaaagta gaatctggaa tgacagttcc
     9661 ggattttttt gatataataa aataatagaa aacgctatca aaagaaggag ggtgatgtcg
     9721 gtgatggaac atttgtttaa attcttactt ttagcaccgt acttttattt tgataactgg
     9781 attgagaagg ccaacagaaa tagtaagttt tttccaattt tttattattt ttactggttt
     9841 tacatcccct tctattctct ttttagcctt gcttggacag ttgtttcagt tctgtttttc
     9901 aataccgtct tgagaaatgt gacagatatc aagttatggg gcatttggtt tctttttatt
     9961 ctgctagcta ttggtatgaa ttggttaact tattcctgtt tcaaagaaat gtttcgcttg
    10021 agacaggaac tagggaagtc taagggtgga aggcattgat ttatatcggt ttctatttgt
    10081 aggaggtggc ttatggtacc tctaaaatca tttattacac gctattccaa ggtttatatt
    10141 ggtaataaca tttaatagaa cgaaactaaa gaaaacaatt taaaaaagga ggcttgtgat
    10201 ggaacacttg tttaaaatga taatcttatt accctgtttt tactttttca gctggattga
    10261 caaggataat agagaaagta aatttttccc aattttttac tatttttact ggatttacat
    10321 caccctctat tctcttttta gccttgcttg gacagttttt tcagttctgt ttttcaatat
    10381 cgtcttgaga aatttgacag atatcaagtt atggggtatt tggctattat tactacttat
    10441 cgcttttgct agtgactggt tagactatat ctgtttcaaa aaaatgcttg acttgagacg
    10501 ggaactaggg aagtctaaag gcggaaggca ttgatttata ctcttcgaaa atctcttcaa
    10561 accacgtcaa cgtcgccttg gattatatat gtaactgact tcgtcagtct tatctacaac
    10621 ctcaaagcag tgctttgagc aacttgcggc tagtttccta gtttgctctt tgattttcat
    10681 tgagtattat attactttct atttgtagga ggtggcttat gaagattcct ctcttaactt
    10741 tggcaaggca taaatttgtt tatgtcttgc ttactttgct ttttcttgct ttggtttatc
    10801 gtgatgtttt gatgacttat ttcttttttg atattcatgc gcccgatcta gctaaattcg
    10861 atggacaagc aattaaaaat gacttattaa aatcagcatt agattttcgt attctccagt
    10921 tcaatctagg tttttatcaa tcatttatta ttccaatcat cattgttttg ctaggttttc
    10981 aatatattga gctgaaaaat aaagttttac gattgagtat tggaagagaa gtgagttatc
    11041 aagggttaaa aagaaagttg actttgcaag ttgcaagtat cccttgtttg atatatttag
    11101 tgactgtgct gataattgca attgtaacct atttctttgg gactttttct cctcttggat
    11161 ggaattctct attttctgat gggagtagtt tacaaaggct cctagatgga gagataacaa
    11221 gctatttgtt ctttacttgt gtcctactaa tcggtatttt catcaatgca gtctattttt
    11281 ttaaaatagt tgattattta ggaaatgtga ctcgttcggc aatcacctat ttgatgtttc
    11341 tttggcttgg ttctatgctg ctctatagtg ccttgcctta ctatatggtt cctatgacga
    11401 gtttgatgca agctagctat ggggatgtaa gtttgatgaa actctttact ccttatatcc
    11461 tttatattgt cccttacatg gtgcttgaaa aatatgaaga taatgtttaa gaattttaac
    11521 aatattttgc taaagagaaa gattgtttta ctacttcgta tagttctgat gatgattttg
    11581 ataaaccatc tattgtcaac agcggttcaa aagcaggatg ctgttatctt tttcaagaga
    11641 gaattgattt caattttttc ctataatgac tattctgaag tgaatttaga aatccccaaa
    11701 ctcttgttaa acctttcgct tttcatggta ggatggctct ctgtcatttt acttgaaagt
    11761 gatttggcag accattacca tcacttgatt cgctatcaat caagctcctt tttcgattat
    11821 acaaggaaac gattggttgt catttctaaa ttttttactc aagatttact tgtctggttc
    11881 cttggtttac ttccgctagg aattcatttc aaaacagtcg cacttttctt tttacttgct
    11941 cagttaatga tgttgtactt actactgtct tatctgatag cactgattag tgcgggcgct
    12001 ggtttttcct tttttctcta ttttttagca tttgtgggac aagaatggat gatggatcat
    12061 attgtaacag tgtatttact actcttaagc ttattagtta tgttgattgt tagtcgcttg
    12121 gaagagaaat ttaagaaagg ataaacgatg aaacttgaaa ttataaatgg acagaaaatt
    12181 tatgggaaaa gacctatttt aaatcagttg aatttggtgt ttcaatcagg aaaaatttat
    12241 ggacttaaag gtgataatgg atctggcaag acggttcttt taaaggtact tgctggttat
    12301 attaagcttg acaaaggaaa agttcttcaa gatggtaaag tttacgggat aaaaaatcat
    12361 tatattcagg atgcaggaat tttaattgaa aaagtcgagt ttttatctca tttatccctg
    12421 agagaaaatt tggaactgtt aaggtatttt tcatctaaag ttacggaaaa aagaattgcc
    12481 tattggattc aatactatga tttacaggaa tttgaagacg ttgaataccg gcatttatcc
    12541 ttgggaacaa agcaaaaaat ggccttgatt caagccttta tttcctctcc ttctatactc
    12601 tttctcgatg aacctatgaa tgctttggat gagaagagtg tgaggttaac caaacaggtc
    12661 attttatctt acctgaaaaa agaaaatggt ctggttatcc tgacgtcgca catatcggaa
    12721 gatatttcag acctttgtac agatgtatta gttgtcgaaa atggacatat acaatatgta
    12781 aaggatatac aatcctagga gatggcttat ggcacatcta aaatcattta ttacacgcta
    12841 ttccaaggtt tatattggtt tagttctgtt gatctggatt gctttcttct ttcttccttg
    12901 gggcagtccg attctggggg ggaagattga cctcttcagc atacagaaag tcttgctagt
    12961 ttttggcatt ctgtccattt tgatggcctt gctgtccaag aaagtcagtc tctttgtttt
    13021 tggattgatc tgctgtcttt ctctttggat taacttattt atcctatttg ctattttgcc
    13081 gattcttggc aattaaagta tcataaaagt cagagaggtt agcttggaaa ctaacctctt
    13141 tttccttttc aaaatgggga ttcttccttg aaaataatca gtaattgtgc taaaattaaa
    13201 ggaacattct aaaatattcg gaatttaaag taaggaaaaa catggctaat attttaaaaa
    13261 caattatcga aaatgataaa ggagaaatcc gtcgtctgga aaagatggct gacaaggttt
    13321 tcaaatacga agaccaaatg gctgctttga ctgacgacca actaaaagca aaaacagttg
    13381 aatttaagga acgttatcaa aatggagaat cactggattc attgctttac gaagcatttg
    13441 cggttgtccg tgaaggtgcc aaacgtgtcc taggtctctt cccttataag gttcaggtca
    13501 tgggggggat tgttcttcac catggtgacg tgccagagat gcgtacaggg gaagggaaaa
    13561 ccttgactgc gaccatgccg gtatacctca atgccctttc aggtaaaggg gttcacgtag
    13621 ttacggttaa tgaatacctg tcagaacgtg acgcgactga gatgggtgaa ttgtactctt
    13681 ggcttggttt gtcagtaggg attaacttgg ctaccaaatc tccaatggag aaaaaagaag
    13741 cctatgagtg tgatattact tactcaacta actcagaaat cggatttgac taccttcgtg
    13801 acaacatggt cgttcgcgct gaaaacatgg tacaacgtcc gcttaactat gccttggtcg
    13861 atgaggttga ctctatcttg attgacgagg ctcgtacacc tttgattgta tcaggtgcca
    13921 atgcggttga aaccagtcag ttgtatcaca tggcagacca ctatgtaaaa tctttgaaca
    13981 aagatgacta catcatcgat gtgcagtcta agactattgg tttgtctgat tcagggattg
    14041 acagggctga aagctacttc aaacttgaaa acctctatga catcgaaaac gtggctttga
    14101 cccactttat cgataacgcc cttcgtgcca actacatcat gcttctcgat attgactatg
    14161 tggtgagcga agagcaagaa atcttgattg tcgaccaatt tacaggtcgt accatggaag
    14221 gtcgtcgtta ttctgatgga ttgcaccaag ctattgaagc caaagaaggt gtgccaatcc
    14281 aggatgaaac caagacatct gcctcaatca cgtaccaaaa ccttttccgt atgtacaaga
    14341 aattgtctgg tatgacgggt acaggtaaga ctgaggaaga agaattccgt gaaatctaca
    14401 acattcgtgt tattccaatc ccaacaaacc gtcctgttca acgtattgac cactcagacc
    14461 ttctttatgc aagtatcgaa tctaagttta aagcggttgt cgaagacgtt aaggctcgtt
    14521 accaaaaggg tcaacctgtc ttggttggta cagtagcggt tgaaactagt gactacattt
    14581 ctaagaaatt ggttgcagct ggtgttcctc acgaagtctt gaatgccaaa aaccactata
    14641 gagaagccca aatcatcatg aatgctggtc aacgtggtgc cgttaccatc gcaaccaaca
    14701 tggcgggtcg tggtaccgac atcaagcttg gtgaaggtgt tcgtgaactt ggaggacttt
    14761 gtgttattgg tacagaacgt catgaaagtc gtcgtatcga taaccagctt cgtggacgtt
    14821 caggtcgtca aggagatcca ggtgagtcac aattctacct atctcttgaa gatgatttga
    14881 tgaaacgttt tggttctgaa cgcttgaagg gaatctttga acgtctcaac atgtctgaag
    14941 aggcgattga gtctcgcatg ttgacgcgtc aggttgaagc agctcagaaa cgtgtcgaag
    15001 gaaataacta cgatacccgt aaacaagtcc ttcaatacga cgatgtcatg cgtgaacaac
    15061 gtgagattat ctatactcaa cgttatgatg tcattactgc agaccgtgac ttggcacctg
    15121 aaattcaggc aatgatcaaa cgcacgattg gtcgtgtcgt tgacggtcat gcgcgtgcta
    15181 aacaagatga gaaactagag gcaattttga acttcgctaa gtataacttg cttcctgaag
    15241 attctattac gatggaagac ttgtcaggct tgtctgataa ggccatcaag gaagagcttt
    15301 tccaacgtgc cttgaaggtt tacgatagtc aggtttcaaa actacgcgat gaagaagcag
    15361 ttaaagaatt ccaaaaagtt ttgattctac gagtggtgga taacaagtgg acagatcata
    15421 tcgatgccct tgatcaattg cgtaacgcgg ttggacttcg tggctatgct cagaacaacc
    15481 ctgttgttga gtatcaggca gaaggtttcc gtatgtttaa tgatatgatt ggttcgattg
    15541 agtttgatgt gacacgcttg atgatgaaag cacaaattca tgaacaagaa agaccacagg
    15601 cagaacgtca tatcagtaca acagcgactc gcaatatcgc tgctcaccaa gcaagtatgc
    15661 cagaagattt ggatttgagc cagattggac gcaatgaact ttgcccatgt ggttctggta
    15721 agaaatttaa aaactgtcac ggtaaaagac aataaaatga gatagtttag aggcggatat
    15781 cttgtgaaaa gtaaattttt actgggtatc cgtttgcttt ataaggagat gagttatggt
    15841 atttacagca aaaagctcta aaataaatat agaagaagtt cgtgccttgt caaaattaga
    15901 aggtcaggct ttggagagga aatcacagcg agatcaagag ctagaagcca ttatacgtgg
    15961 agaagaccag cgaattctct tggtaatcgg gccatgctca tctgacaacg aagaagctgt
    16021 ccttgaatac gctaagcgtt tggcagtcct acaagaagaa gtggcagatc gtatctttat
    16081 ggttatgcgt gtttatactg ccaaaccccg taccaacgga gatggctata agggcttgat
    16141 tcaccagcct aacgcgacag aagcgcctag tcttatcaat ggaatcaaag ccgttcgcca
    16201 tcttcactat cgtgtcatca cagaaacagg gatgacaact gctgatgaaa tgctttatcc
    16261 tgaaaacctt ccgcttgtag atgatttgat ttcttacatg gcagttggtg cccgttcagt
    16321 tgaagaccag caacaccgct ttgtggcaag tggggcagga ttttctactg gttttaaaaa
    16381 tccaacctct ggaaatctca atgtcatgtt taatgggatt tatgctgctc aaaacaaaca
    16441 aagtttcctt ttcttaggaa aagaagtaga aacaactggg aacccgcttt cacacgctat
    16501 tcttcgtggt gctcttaatg agtatggaaa aaatattccc aactactatt atgacaattt
    16561 aattgatacc attgcccagt atgagaaaat gggcttggaa aatcctttta tcatcattga
    16621 taccaatcat gacaattctg gtaagcagta tattgaacag atccgaattg tccgccagac
    16681 cttgattaac cgtgcttgga atgaaaaaat taagcagttc gttcgtggtt ttatgattga
    16741 gtcttatctg gaagatggtc gacaaaatga gccagaagta tttggtaagt ctatcacaga
    16801 cccttgcctg ggttgggata acacagaagc tcttgtcaga gaaatttaca aaacgttagg
    16861 agaataagat ggcatttatt gaaaaaggtc aagaaatcga tatggaagtc atcaaggctg
    16921 aaacccaatt gtctgcggaa gccttgagac tcaaggaaag ccgtgacagg gaattggcag
    16981 atattatttc aggggaagat gaccgtattc tcttggtgat tggtccttgc tcttctgata
    17041 atgaagaggc ggtcttggaa tatgctcgcc gtttatctgc cttgcaaaag aaggtagcgg
    17101 ataagatttt catggtcatg cgcgtgtata ctgctaagcc tcgtaccaat ggagacggct
    17161 ataaaggatt agttcaccag ccagatactt ctaaggctcc aagcctgatt aatggcttgc
    17221 aggctgtgcg ccagttgcac taccgcgtga ttacagagac tggtttgaca acggcagatg
    17281 agatgcttta tccgtcaaat ctgatcttgg tggatgactt ggtcagctac catgccgttg
    17341 gagctcgttc tgtggaagac caagagcacc gctttgtggc ttctgggatt gatgcaccag
    17401 tagggatgaa aaatccaacc tcaggaaatt tgggtgttat gtttaacgcc atctatgctg
    17461 ctcaaaacaa gcaaaccttc ctttatcatg ggcaggaagt tgagacatca ggtaatcctt
    17521 tggcccatgt tatcctccgt ggagcagtca acgagtatgg caattatatg ccgaattact
    17581 actatgaaaa tctactccaa gccattgaac gctatgaaac catgggactt gaaaatcctt
    17641 ttatcctcat tgacaccaac catgataact caggcaagca atatatggag cagattcgaa
    17701 ttgttcgcca gaccttgcag aatcgtgatt ggaatgagaa aattaaaaag acggttcgag
    17761 gatttatgat tgaatcttac ctagcagatg gtcgtcaaaa ccaaccagag atctttggtt
    17821 gctctattac tgacccttgc ctaggttggg aaaatacaga ggccttggta gaagagattt
    17881 atgttacctt gacaaaataa gtgaaaagga tggagttggg gaatctcaac tccttttgat
    17941 gagaatgata gttggacacg gaattgacat cgaagaattg gcttcgatag aaagcgcagt
    18001 tacacgacat gaaggatttg ctaagcgtgt actgaccgct caggaaatgg agcgcttcac
    18061 cagtctcaaa ggacgcaggc aaatagaata tttagctggt cgctggtcgg ctaaggaggc
    18121 cttttccaag gctatgggaa cgggcattag caagctcggt tttcaggatt tggaagtctt
    18181 gaacaatgaa cgtggggcgc cttattttag tcaggcacca ttttcaggaa agatttggct
    18241 gtctatcagc cacaccgatc agtttgtgac agccagtgtc attttggagg aaaatcatga
    18301 aagctagtcc acatagacca accaaggctc tgattcatct gggagctatt cgacaaaata
    18361 ttcagcaaat gggggctcat atccctcaag gaacgctcaa gttggctgtg gttaaggcca
    18421 atgcttatgg tcatggagct gttgccgttg ccaaggcaat tcaagatgat gttgatggct
    18481 tttgcgtttc caatatcgat gaagccattg aactcagaca agctggactc agcaagccaa
    18541 tcctcatttt aggagtttct gaaatcgaag ctgttgctct agctaaagaa tatgacttca
    18601 ccttgacagt ggctggactg gagtggattc aagcactctt agataaggaa gtggacctaa
    18661 ctggattgac agtccacctc aagattgatt cagggatggg acggattggt tttagagagg
    18721 caagtgaggt tgagcaggct caagatttgc tccaacaaca cggtgtttgt gttgaaggaa
    18781 tctttaccca ctttgctact gctgatgagg aatcagatga ctattttaat gcccagttag
    18841 aacggtttaa aactatttta gctagtatga aggaagttcc agagctggtt catgctagca
    18901 attctgcaac gactctttgg catgtagaga ctattttcaa tgcggttcgt atgggagatg
    18961 ccatgtatgg cctcaatcca agtggagcgg tcttggattt gccttatgat ttgataccgg
    19021 ccttgacctt ggagtctgct ctggttcatg tcaagacagt tccagctgga gcttgcatgg
    19081 gctatggagc aacttatcaa gcggatagcg agcaagtcat cgcgaccgtg ccaatcgggt
    19141 atgcagatgg atggacaaga gacatgcaaa atttctctgt cttggtagat ggccaagctt
    19201 gcccaattgt cggcagggtt tcgatggacc aaatcactat tcgattgcct aagctttatc
    19261 cgctaggaac caaggtaacc ttgattggct ccaatgggga taaggaaatc actgcaactc
    19321 aggtagcgac ctaccgcgta accattaact atgaggtggt ttgcctcctc agcgaccgta
    19381 ttccgagaga atattattag aaaagaaagg agtggagcat gaatctacat caacccttgc
    19441 atgtcttgcc tggtgtggga ccaaagtcag cagaaaaata cgccaaacta ggaattgaaa
    19501 acttgcaaga tctcttgctc tactttcctt tccgttatga agacttcaaa accaagcagg
    19561 tgctggagct ggaagacggt gagaaggcag ttctttctgg tcaggtagtg actcctgcta
    19621 gtgtccagta ttatggtttc aagcgcaatc gcctgcgttt tagtctcaag cagggagagg
    19681 tcgtttttgc ggtgaatttc tttaaccagc cctatctggc tgataaaata gagttgggag
    19741 caacccttgc tgtctttgga aaatgggacc gcgctaaggc tagtctgact gggatgaagg
    19801 ttctggctca ggtagaagat gacctccagc ctgtctatcg tctggctcag ggaatcagtc
    19861 aggccagtct ggtcaaggtc atcaagacgg cttttgatca gggactggac ctcttgatag
    19921 aagaaaatct gccccagtct ttactagaca aatacaaact catgtcccgt tgtcaggcag
    19981 tccgtgctat gcattttcca aagtatttgg cagaatacaa gcaggctctt cgccgtataa
    20041 agtttgagga actcttttat ttccaaatgc agctgcagat gctcaagtct gaaaatagag
    20101 ttcagggaag tggtctggtt ctgaattggt ctcaggaaaa agtgacagca gttaaagtaa
    20161 gtcttccttt tgccctgacc caagctcagg aaaagagttt gcaggaaatt ttaactgata
    20221 tgaagtccga ccaccacatg aatcgtctcc tacaagggga tgtggggagt ggaaaaacgg
    20281 tagtcgctgg cttggccatg tttgcggcag tgacagcagg ttatcaggct gccctaatgg
    20341 taccaacaga aatcctcgca gagcaacact ttgagagttt acagaacctt tttcccaatt
    20401 tgaaactggc tctcttgaca ggttccttga aagctgcaga aaagagagaa gtcttggaga
    20461 ccattgccaa gggtgaggct gatttgatta taggaactca cgctctgata caagatgggg
    20521 tggagtatgc tcgtcttggt ttgattatta tcgatgagca gcaccgtttt ggtgtagggc
    20581 aaaggcgtat tttacgggaa aaaggtgaca atccagatgt cctcatgatg acggcgactc
    20641 ccattccacg gacgcttgcc atcacagcct ttggagatat ggatgtttcc attatcgacc
    20701 agatgccagc aggtcggaag cctattgtga cgcgctggat caaacatgag caactacctc
    20761 aggtcttgac ttggttagag ggggaaattc aaaaaggttc ccaagtctat gtcatctctc
    20821 ctttgattga agaatcagaa gctctagatt tgaaaaatgc cattgcctta tcagaggagt
    20881 tgacgactca ttttgcaggc aaggcagagg tggctcttct acatggtagg atgaagagtg
    20941 acgaaaaaga ccagatcatg caggatttca aggagagaaa gacggatatt ctggtttcga
    21001 cgacggttat tgaggttggg gtcaacgttc ccaatgcgac tgtcatgatt atcatggatg
    21061 ccgatcgctt cggtctcagt caacttcacc agcttagagg tcgtgtcggt cggggggaca
    21121 agcagtccta cgctgttctc gttgctaatc ccaagacgga ttctgggaaa gaccgcatgc
    21181 gtatcatgac agaaacgacc aatggatttg tccttgcgga ggaagatttg aaaatgcgtg
    21241 gttctggtga gatttttgga accagacagt caggacttcc agagttccaa gtggctgata
    21301 ttatcgaaga ttttccgatt ttagaagaag caagaaaggt tgctagctac attagttcta
    21361 tagaagcttg gcaagaagat ccagagtggc gcatgattgc ccttcatctg gaaaagaaag
    21421 aacatctgga ttaagctttc tctaaggaaa acttaagcta gtttttaggt ttggctctta
    21481 tactaaagtc atcaaaaaga aacgaggact ctcatatgac agtaacgatt aaagtaaatt
    21541 accaaaccac tttccaaaag aaggaagcaa aaaactagta taaacagaag agagagcgaa
    21601 atgctctttt tcgtttctaa aactactttc agcccatcat cctaaaagta aagaatctaa
    21661 attcactttc tatttatcct tctttcttgc attgattaca tagatatgct acagttgtgg
    21721 taacgattac aaaataaaag gagcatgcta tgaaaaatcc agctttgcta gaagaaatta
    21781 agacctatag aggaagggat gaggttccgg aagactttga tgctttctgg gatggggaag
    21841 tgaaaaatgt ttccacgctt ccatcctacc acttggagga aagagatttc cacattcctc
    21901 aagtcaagtg ctatgagtta acatttgaag gaagcaagga aggaaaggtc tatgcacgca
    21961 ttgttcttcc aaagagtgag gagaaggttc cattaatctt ccattttcat ggttatatgg
    22021 gacgtggctg ggactgggcc gacatgctgg gcttcaccgt agctggttac ggtgttgttt
    22081 ccatggatgt gcggggccag tcaggttact cacaagacgg cttgcgttct cctttaggaa
    22141 ataccgtgaa ggggcatatt atccgtggtg ctgtggaagg tcgggaccac ctcttttata
    22201 aggatgttta tctggatatt taccagttgg tcgaaattgt tgctagtctg tctcaggttg
    22261 atgagaagcg tctttctagc tatggtgcct cacaaggagg ggctctagcc ctagttgcag
    22321 cagcgctcaa tcctcgaatt cagaaaacag ttgccattta tcccttcttg tcagacttca
    22381 gacgggtgat tgagattggt aatactagcg aggcttacga cgaacttttc cgttatttca
    22441 agttttacga ccccttccat gaaacagagg aggaaatcat ggcgaccctt gcctatatcg
    22501 atgtcaaaaa tcttgcccat cgtatccaag gtgaggttaa gatgattacg ggcttggacg
    22561 acgatgtttg ctatcccatt acccagtttg cgatttataa tcgtctgacc tgcgataaaa
    22621 cctatcgtat catgcctgag tatgctcacg aagccatgaa tgtatttgtt aatgaccaag
    22681 tctacaactg gctctgtgga agtgagattc cttttaaata tctaaaataa ggagtcgact
    22741 ctaagcacaa aatcttaaaa attacaaaca cgcatagtat caggggatta agaaaacttg
    22801 atactatgcg ttttatcata gaaatatagt aaaatgaaac aagaacagga caaatcgatc
    22861 aggacagtca aatcgatttc taacaatgtt ttagaagtag atgtgtacta ttctagtttc
    22921 aatctattat atttatagaa ttttttgttg ctagatttgt caaattgctt aaaataattt
    22981 ttttcagaaa gcaaaagccg atacctatcg agtagggtag ttcttgctat cgtcaggctt
    23041 gtctgtaagt gttaatactt ttcaaaaatc tcttcaaacc acgtcagctt cgccttgccg
    23101 tatatatgtt actgacttcg tcagttctat ctgccacctc aaaacggtgt tttgagcatc
    23161 atgcggctag cttcttagtt tgctctttga ttttcattga gtataaaaac agatgagttt
    23221 ctgttttctt tttatggact ataaatgttc agctgaaact actttcaagg acattattat
    23281 ataaaagaat tttttgaaac taaaatctac tatattacac tatattgaaa gcgttttaaa
    23341 aatgaggtat aataaattta ctaacgctta taaaaagtga tagaatctat ctttatgtat
    23401 atttaaagat agattgctgt aaaaatagta gtagctatgc gaaataacag atagagagaa
    23461 gggattgaag cttagaaaag gggaataata tgatatttaa ggcattcaag acaaaaaagc
    23521 agagaaaaag acaagttgaa ctacttttga cagttttttt cgacagtttt ctgattgatt
    23581 tatttcttca cttatttggg attgtcccct ttaagctgga taagattctg attgtgagct
    23641 tgattatatt tcccattatt tctacaagta tttatgctta tgaaaagcta tttgaaaaag
    23701 tgttcgataa ggattgagca ggaagtatgg tgtaaatagc ataggctgat gtccatcatt
    23761 tgcttataaa gagatatttt agtttaattg cagcggtgtc ctggtagata aactagattg
    23821 gcaggagtct gattggagaa aggagagggg aaatttggca ccaatttgag atagtttgtt
    23881 tagttcattt ttgtcattta aatgaactgt agtaaaagaa agttaataaa agacaaacta
    23941 agtgcatttt ctggagtaaa tgtcttattt cagaaatcgg gatatagata tagagaggat
    24001 cagtatgaat cggagtgttc aagaacgtaa gtgtcgttat agcattagga aactatcggt
    24061 aggagcggtt tctatgattg taggagcagt ggtatttgga acgtctcctg ttttagctca
    24121 agaaggggca agtgagcaac ctctggcaaa tgaaactcaa ctttcggggg agagctcaac
    24181 cctaactgat acagaaaaga gccagccttc ttcagagact gaactttctg gcaataagca
    24241 agaacaagaa aggaaagata agcaagaaga aaaaattcca agagattact atgcacgaga
    24301 tttggaaaat gtcgaaacag tgatagaaaa agaagatgtt gaaaccaatg cttcaaatgg
    24361 tcagagagtt gatttatcaa gtgaactaga taaactaaag aaacttgaaa acgcaacagt
    24421 tcacatggag tttaagccag atgccaaggc cccagcattc tataatctct tttctgtgtc
    24481 aagtgctact aaaaaagatg agtacttcac tatggcagtt tacaataata ctgctactct
    24541 agaggggcgt ggttcggatg ggaaacagtt ttacaataat tacaacgatg cacccttaaa
    24601 agttaaacca ggtcagtgga attctgtgac tttcacagtt gaaaaaccga cagcagaact
    24661 acctaaaggc cgagtgcgcc tctacgtaaa cggggtatta tctcgaacaa gtctgagatc
    24721 tggcaatttc attaaagata tgccagatgt aacgcatgtg caaatcggag caaccaagcg
    24781 tgccaacaat acggtttggg ggtcaaatct acagattcgg aatctcactg tgtataatcg
    24841 tgctttaaca ccagaagagg tacaaaaacg tagtcaactt tttaaacgct cagatttaga
    24901 aaaaaaacta cctgaaggag cggctttaac agagaaaacg gacatattcg aaagcgggcg
    24961 taacggtaaa ccaaataaag atggaatcaa gagttatcgt attccagcac ttctcaagac
    25021 agataaagga actttgatcg caggtgcaga tgaacgccgt ctccattcga gtgactgggg
    25081 tgatatcggt atggtcatca gacgtagtga agataatggt aaaacttggg gtgaccgagt
    25141 aaccattacc aacttacgtg acaatccaaa agcttctgac ccatcgatcg gttcaccagt
    25201 gaatatcgat atggtgttgg ttcaagatcc tgaaaccaaa cgaatctttt ctatctatga
    25261 catgttccca gaagggaagg gaatctttgg aatgtcttca caaaaagaag aagcctacaa
    25321 aaaaatcgat ggaaaaacct atcaaatcct ctatcgtgaa ggagaaaagg gagcttatac
    25381 cattcgagaa aatggtactg tctatacacc agatggtaag gcgacagact atcgcgttgt
    25441 tgtagatcct gttaaaccag cctatagcga caagggtgat ctatacaagg gtaaccaatt
    25501 actaggcaat atctacttca caacaaacaa aacttctcca tttagaattg ccaaggatag
    25561 ctatctatgg atgtcctaca gtgatgacga cgggaagaca tggtcagcgc ctcaagatat
    25621 tactccgatg gtcaaagccg attggatgaa attcttgggt gtaggtcctg gaacaggaat
    25681 tgtacttcgg aatgggcctc acaagggacg gattttgata ccggtttata cgactaataa
    25741 tgtatctcac ttaaatggct cgcaatcttc tcgtgtcatc tattcagatg atcatggaaa
    25801 aacttggcat gctggagaag cggtcaacga taaccgtcag gtagacggtc aaaagatcca
    25861 ctcttctacg atgaacaatg aacgtgcgca aaatacagaa tcaacggtgg tacaactaaa
    25921 caatggagat gttaaactct ttatgcgtgg tttgactgga gatcttcagg ttgctacaag
    25981 taaagacgga ggagtgactt gggagaagga tatcaaacgt tatccacagg ttaaagatgt
    26041 ctatgttcaa atgtctgcta tccatacgat gcacgaagga aaagaataca tcatcctcag
    26101 taatgcaggt ggaccgaaac gtgaaaatgg gatggtccac ttggcacgtg tcgaagaaaa
    26161 tggtgagttg acttggctca aacacaatcc aattcaaaaa ggagagtttg cctataattc
    26221 gctccaagaa ttaggaaatg gggagtatgg tatcttgtat gaacatactg aaaaaggaca
    26281 aaatgcctat accctatcat ttagaaaatt taattgggac tttttgagca aagatctgat
    26341 ttctcctacc gaagcgaaag tgaagcgaac tagagagatg ggcaaaggag ttattggctt
    26401 ggagttcgac tcagaagtat tggtcaacaa ggctccaacc cttcaattgg caaatggtaa
    26461 aacagcgact ttcctaactc agtatgatag caagaccttg ttgtttgcag tagataagga
    26521 agatatcgga caggaaatta ttggtatagc taaaggaagc atcgaaagta tgcataatct
    26581 tcctgtaaat ctagcaggtg ccagagttcc tggcggagta aatggtagca aagcagcggt
    26641 gcatgaagtt ccagaattta cagggggagt taatggtaca gagccagctg ttcatgaaat
    26701 cgcagagtat aagggatctg attcgcttgt aactcttact acaaaagaag attatactta
    26761 caaagctcct cttgctcagc aggcacttcc tgaaacagga aacaaggaga gtgacctcct
    26821 agcttcacta ggactaacag ctttcttcct tggtctgttt acgctaggga aaaagagaga
    26881 acaataagag aagaattcta aacatttgat tttgtaaaaa tagaaggaga tagcaggttt
    26941 tcaagcctgc tatctttttt tgatgacatt caggctgata cgaaatcata agaggtctga
    27001 aactactttc agagtagtct gttctataaa atatagtaga ttgaaataag atgtgaacaa
    27061 ctctatcagg aaagtcaaat taatttatag aaaaatttta gcagtcaagg tgtactgtta
    27121 tagattcaat atattatgtg actat
//
LOCUS       DAVKBC010000026        26101 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVKBC010000026 DAVKBC010000000
VERSION     DAVKBC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.026"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(178..1848)
                     /locus_tag="VWX64_001292"
     CDS             complement(178..1848)
                     /locus_tag="VWX64_001292"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU9190761.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            2078..2767
                     /gene="coaB"
                     /locus_tag="VWX64_001293"
     CDS             2078..2767
                     /gene="coaB"
                     /locus_tag="VWX64_001293"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU9190762.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISTDQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2779..3330
                     /gene="coaC"
                     /locus_tag="VWX64_001294"
     CDS             2779..3330
                     /gene="coaC"
                     /locus_tag="VWX64_001294"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU9190763.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLITPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            3314..3877
                     /locus_tag="VWX64_001295"
     CDS             3314..3877
                     /locus_tag="VWX64_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9190764.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            4159..4686
                     /locus_tag="VWX64_001296"
     CDS             4159..4686
                     /locus_tag="VWX64_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9190765.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            4698..5213
                     /locus_tag="VWX64_001297"
     CDS             4698..5213
                     /locus_tag="VWX64_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU9190766.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(5210..5677)
                     /locus_tag="VWX64_001298"
     CDS             complement(5210..5677)
                     /locus_tag="VWX64_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9190767.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(5751..6239)
                     /locus_tag="VWX64_001299"
     CDS             complement(5751..6239)
                     /locus_tag="VWX64_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190768.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            complement(6205..6768)
                     /locus_tag="VWX64_001300"
     CDS             complement(6205..6768)
                     /locus_tag="VWX64_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190769.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLVLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            complement(6778..8766)
                     /gene="uvrB"
                     /locus_tag="VWX64_001301"
     CDS             complement(6778..8766)
                     /gene="uvrB"
                     /locus_tag="VWX64_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU9190770.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(8843..9796)
                     /locus_tag="VWX64_001302"
     CDS             complement(8843..9796)
                     /locus_tag="VWX64_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9190771.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            9966..12131
                     /locus_tag="VWX64_001303"
     CDS             9966..12131
                     /locus_tag="VWX64_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9190772.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            12131..12871
                     /locus_tag="VWX64_001304"
     CDS             12131..12871
                     /locus_tag="VWX64_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9190773.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            13020..14507
                     /locus_tag="VWX64_001305"
     CDS             13020..14507
                     /locus_tag="VWX64_001305"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU9190774.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDLEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPPHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(14551..15840)
                     /gene="ftsY"
                     /locus_tag="VWX64_001306"
     CDS             complement(14551..15840)
                     /gene="ftsY"
                     /locus_tag="VWX64_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU9190775.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTIEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(15844..16662)
                     /locus_tag="VWX64_001307"
     CDS             complement(15844..16662)
                     /locus_tag="VWX64_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9190776.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYADVARLYEKTE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGINQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(16662..17456)
                     /locus_tag="VWX64_001308"
     CDS             complement(16662..17456)
                     /locus_tag="VWX64_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9190777.1"
                     /translation="MTIKLVATDMDGTFLDENGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYI
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            complement(17453..20992)
                     /gene="smc"
                     /locus_tag="VWX64_001309"
     CDS             complement(17453..20992)
                     /gene="smc"
                     /locus_tag="VWX64_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU9190778.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQTQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEVALKTLQDEMARLTESLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDRYEEVHNRLDFLNSQRDDILSAKNLLLETITKMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(20983..21681)
                     /locus_tag="VWX64_001310"
     CDS             complement(20983..21681)
                     /locus_tag="VWX64_001310"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU9190779.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(21864..21935)
                     /locus_tag="VWX64_001311"
     tRNA            complement(21864..21935)
                     /locus_tag="VWX64_001311"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21900..21902),aa:Arg,seq:ccg)
     gene            complement(21999..22985)
                     /locus_tag="VWX64_001312"
     CDS             complement(21999..22985)
                     /locus_tag="VWX64_001312"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU9190780.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            complement(23160..24476)
                     /locus_tag="VWX64_001313"
     CDS             complement(23160..24476)
                     /locus_tag="VWX64_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU9190781.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            complement(24463..25722)
                     /locus_tag="VWX64_001314"
                     /pseudo
     CDS             complement(24463..25722)
                     /locus_tag="VWX64_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
BASE COUNT         7595 a         5813 c         4686 g         8007 t
ORIGIN      
        1 ttgaggttgt ggatagaact gacagagtca gtatcatatt acctacggca aggtgaagct
       61 gacgtagttt gaaaagattt tcgaagagta taaatcttat tgatgaactg cttgcagtct
      121 gagaaaaaat gagcttggat attatttcca aactcactta aagtcaattt caatccacta
      181 gaacaagcct agtacagttc catcgctttc aacatccatg ttgagagctg ctggacgttt
      241 tggaagacct ggcatggtca taacatcacc agttaaggca acgatgaagc ctgcacctaa
      301 ttttggtacc aattcacgaa tggtaatttc aaagttttct ggtgctccaa gcgcatttgg
      361 attgtctgag aaactgtatt gagttttagc catacaaatt ggcaatttgt cccaaccgtt
      421 ttgaacgatt tgagcaattt gtgtttgagc tttcttctca aagttcactt tgctaccacg
      481 atagatttca gtgacaattt tttcaatctt ttcttggaca gaaaggtcat tatcgtacaa
      541 acgtttatag ttagctggat tttcagcaat tgtcttaaca actgtttcgg caagtgctac
      601 tccaccttct gctccatcag cccagacact agccaattca actggtacat cgattgaggc
      661 acagagttct tttaaggctg caatttcagc ttctgtatca gatacaaatt cgttaatagc
      721 tacaactgct ggaataccga acttacggat attttcaacg tggcgtttca agttagcaaa
      781 acctgcacga actgcctcta cattttcttc agtcagagcg tctttagcca caccaccatt
      841 catcttaagg gcacgaaggg ttgcgacaat aacaactgca tctggagatg ttggcaagtt
      901 tggtgtcttg atatcaagga atttctcagc accaaggtcc gcaccaaaac cagcttcagt
      961 aacagtgtaa tcagccaagt gaagggctgt tgtcgtcgcc aaaacagagt tacagccatg
     1021 agcgatattg gcaaatggac caccgtgtac aaaggcaggt gtaccgtaaa ttgtctgaac
     1081 caagtttggc ttaatagcat ccttcaaaat caaagccaag gcaccctcaa cctgcaaatc
     1141 acctacagaa acaggcgtac ggtcatagcg ataaccaata acgatattcg ccaaacgacg
     1201 tttcaagtcc tcgatgtccg ttgccaagca aagaattgcc atgatttctg aagcaactgt
     1261 aatatcaaaa ccatcctcac gtggaatacc gtttagagga ccaccaagac caacagtcac
     1321 atggcggagc gcacggtcgt tcaagtccac aacgcgtttc cagaggatac gacgttgatc
     1381 aattcccagc tcattccctt ggtgcaagtg gttgtcaatc aaggcagaaa gggcattgtt
     1441 ggcagttgta atagcatgca tatctccagt aaagtggagg ttgatgtctt ccattggcag
     1501 aacttgtgca tacccaccac cagcagcacc acccttgatc cccatgactg gaccaagaga
     1561 cggttcgcgg atagcaatca tggttttctt gccaatcttg ttcaaggcat ccgcaagacc
     1621 aatggtaagc gtcgactttc cttcacctgc aggtgttggg ttgatggcag taaccaagat
     1681 caatttaccg actggattgc tctcaactgc acgaatttta tcaaagctga gtttagcctt
     1741 gtactttccg tacaactcca aatcgtcgta agaaatacca agtttctcta caacatcaac
     1801 aattggcttc aactcaatac tctgtgcgat ttcaatatct gttttcattc aaaattcctc
     1861 taacctctta tatgataatt cattatatca caaaacaaga tttttaacat cctaaaactc
     1921 tctaaacgtt cgtaaatatc tctgttttta agacttttag agtcctttct taaatttttt
     1981 atggctttat agtttgaaac tataataaat cttcgttttt accaaaaatt tatcactttc
     2041 attttactta ccgcttattt ttgtgtacaa tagtgctatg aaaattttag ttacatcggg
     2101 cggtaccagt gaagctatcg atagcgtccg ctctatcact aaccattcta caggtcactt
     2161 ggggaaaatt atcacagaga ctttgctttt tgcagggcat gaagtttgtt taattacgac
     2221 aaaacgagct ctgaagccag agcctcatcc taacctaagt attcgagaaa ttaccaatac
     2281 caaggacctt ctaatagaaa tgcaagaacg tgttcaggat tatcaggtct tgatccactc
     2341 aatggctgtt tctgactaca ctcctgttta tatgacaggg cttgaggaag ttcaggctag
     2401 ctccaatcta aaagaatttt taagcaagca gaatcatcag gccaagattt cttcaactga
     2461 tgaggttcag gttttgttcc ttaaaaagac acccaaaatc atatccctag tcaaggaatg
     2521 gaatcctact attcatctga ttggtttcaa actgctggtt gatgttaccg aagatcatct
     2581 ggttgacatt gcacgaaaaa gtcttatcaa gaatcaagca gatttaatca tcgcgaatga
     2641 cctgactcaa atttcaacag atcagcaccg agctatattt gttgagaaaa atcagcttca
     2701 aacagtccag actaaagaag aaattgcaga actcctcctt gaaaaaattc aagcctatca
     2761 ttcttagaaa ggaaaactat ggcaaacatt ctcttggctg taacgggttc aatcgcctct
     2821 tataagtcgg cagatttagt cagttctcta aaaaaacaag gccatcaagt cactgtctta
     2881 atgactcagg ctgctacaga gtttatccaa cctttgacac tacaggtact ctcacagaat
     2941 cctgtccact tggatgtcat gaaggaaccc tatcctgatc aggtcaatca tatcgaactt
     3001 ggaaaaaaag cagatttatt tatcgtggta cctgcaactg ctaacactat tgcaaaacta
     3061 gctcacggat ttgcggacaa catggtaacc agtacagctc tagccctacc aagtcatatt
     3121 cccaaactaa taactcctgc tatgaataca aaaatgtatg accatccagt aactcagaat
     3181 aatctgaaaa cattagaaac ctacggctat cagctgattg ctcctaagga atccctacta
     3241 gcttgtggag accacggacg aggagcttta gctgacctca caattatttt agaaagaata
     3301 aaggaaacta tcgatgaaaa aacgctctaa tattgcaccc attgctatct tttttgctac
     3361 catgctcgtg atacactttc tgagctcact tatctttaac ctttttccat ttccaatcaa
     3421 accgaccatt gttcatattc ctgtcattat tgccagcatt atttatggtc cacgagttgg
     3481 ggttacactt ggatttttga tgggattact tagcttgacg gttaacacga ttacgattct
     3541 accgacaagc tacctcttct ctcccttcgt accaaacgga aacatctact cagctatcat
     3601 tgccattgtc ccacgtattt tgattggttt aactccttac ttagtctata aactgatgaa
     3661 aaacaagact ggtctgattt tagctggggc ccttggttcc ttgacaaata ctatctttgt
     3721 ccttggagga atcttcttcc tatttggaaa tgtttataat ggaaatatcc aacttcttct
     3781 ggcaaccgtt atctcaacaa attcaattgc tgaattggtc atttctgcaa ttctaaccct
     3841 agccattgtt ccacgactac aaaccttgaa aaaataaaaa caatctccgc tttcaaacct
     3901 gaaggtggag attttgctct atacagtttc tttttaatga aatctttact atagtaaaac
     3961 gaaataagaa caggacaaat cgatcaggac agccaaatcg atttctaaca atgttttaga
     4021 agtagaggtg gactattcta gtttcaatct actataactt ttaactaaaa aatgatctat
     4081 aaacccaagt aaattcttgc tttattgtct ggtttattgt accatactag tgtatatgca
     4141 gttaaaaagg agattcttgt gaatacacgg aaaaagacac aatttatgac aatgacagcc
     4201 cttttaacgg ctattgcgat tttgattcca attgttatgc ctttcaagat tgtcattcca
     4261 cctgcttcct atactttggg gagccacatc gctattttta tagccatgtt cttgtcgccc
     4321 ttgatggcag tttttgtcat cctagcctct agttttggat ttttgatggc tggctatccc
     4381 atggttatcg tttttcgggc tttttcccat atatcttttg gtgctttagg agctctttac
     4441 ctacaaaaat tccccgatac cctagataaa ccaaaatctt cctgggtttt caactttgtt
     4501 ttggctgttg ttcatgccct tgctgaagta ttagcctgtg tcctttttta cgcaacttcg
     4561 ggtaccaatg tagaaaacat gttctatgtt ctatttgtac tagttggatt tggcacaatt
     4621 atccatagta tggtagacta tacattagca ctagctgtct ataaagtgct tcgaaaacgc
     4681 cgttaaaagg aaaagctatg acaaaagatc gcaaacaagc cctgctccaa ctcttgaaag
     4741 aagctcctaa agcccttaat ggccaaagtt tggcggaaca ttttcatgtc acacgtcagg
     4801 tcattgtgca ggacattgca attttgagag ccgatggcgc tcctatccta tccaccaatc
     4861 gtggctacat ctataagcaa attgatacca atccttatgt tcacaaactt ttcaaagtga
     4921 aacatgaagt tgaagaaatc ggtcaggaac tccttgctat tgtcgataat ggcgggcatg
     4981 tccagaatac cttgattgac catcccgttt atggagaaat tgaaaccttg cttaaactgt
     5041 cttgtcgcag agatgtgcaa cattttctag aacaagtcga gcattctgac tttagacctc
     5101 tatctgaatt gacagatggc atccattacc acctagtcga agccgaaaca caacaagacc
     5161 tccactatat cgaggaggcc ttggatcagc taggttattt agtaaaagac tagaagattt
     5221 tcttttccca atcgtcttct gtacggcgag gatagaaaaa ctctgacttg tcgggagctt
     5281 ccatcatttc catcaatggt agcatatcat aggccagatt taagtttgga atctggtctt
     5341 tttgcaccca agaaacttct ccctcttctg aagattgaag ggtaccagag aactcagtcg
     5401 ccttataaca aatgacaata tagcgcccac ctgtatctag tggccaattt ttaatgccga
     5461 caagttgagg attttggata gtcaaccctg tttcttcgta gatttcacga atgacagact
     5521 ccgcaaaagc ctcatcattt tctacatgac ctccaggaaa ggcataacca gaccagcgat
     5581 tgttttcagg ggcgcgatac tgcatcacca cgcgctgagt ttcgaggtct tcaatcagac
     5641 agatatttgt taaaattgtt aattgggaac gggacataaa tttactcgct ttctaattta
     5701 ttaaattttc agacttacta ccagagatat tatcttttac ttttttaaaa ttatttagaa
     5761 tagaacacca ttcgtttttc ctttataggc tttccaagtt caagtatttt ttcttgtcca
     5821 tcaaaagtaa aacccatttt ttgatagaaa gcaatggcgc gcttgttatc tttcaatacc
     5881 cataagaaaa tttcagaaaa atgattaaga gcagtcaaag ctgctttcat taacttttgt
     5941 gcgatacctt ttccataata gtcttttaaa acatataaag caataatttc accagcttga
     6001 atagtctcat cacgaaaatt gccataactg ataaaaccaa ccaccttcac gccatccatc
     6061 gcaatcaatg tattttctgg atacttttga ctaaagaatc gacatctttc taatgtcatt
     6121 gtatcctgaa attccgcagg caaaaggtca tcataagact ctctccacgt ttgccagtga
     6181 acgagggatt tgccttctat ctcttcagga gtttccattg atttgataat aaccgtcatt
     6241 tattttctcc cagtcttctc tcaaaatacc atatttaata ctatcaaaat atttaccttg
     6301 ataataacga acttttggaa tatgagcttc ttttttcatt cttaattttt cagcaagttt
     6361 catcatacca atatttcctg accaagttgt caaaaccaga tgctccaact ccaagtaatc
     6421 ctgaaacgtc ctatctatcc actgcaacat agcaactttc ccaataccag tgttccagaa
     6481 ttttttatca taaataccaa ttcccaattc catccatctt gtttctttac atacccaata
     6541 acgcgaaaca gtcccaacta gtttatcatc aacaaaaata ccaaggcgat ttgagttgct
     6601 taaaatggat tctgattttt gtagttcgaa ttctttaaaa tttgaaaaat actgataatc
     6661 atcataatag ggagcatcat actgtttcca aactggatta agttgtgaat aagccatttc
     6721 ccataaagac atcaaatctt ctctctttaa ctttcttaaa taaatcatac tattccccta
     6781 atccaaggcc ttgacttcca acatcatatc acggatctga gccgccagtt caaagtcaag
     6841 cacttcgacg gcttcttgca tttgtttttc tagtttcttg acgagttctt tgcgctcttg
     6901 tttgttgagg ctattgatgt cgacttcctt gtcctcttcc ttagcaactg ccttggtcac
     6961 ggcaatcagg tcacggattt ctttcttgat tgtctgtggt acgataccat gctcttcatt
     7021 ataggccatc tgaattttcc gacggcgggc agtttcatcg atagcacgtt gcatagactg
     7081 ggtaaccgtg tctgcataca tgatgacatg gccttcactg ttacgagcag cacgtccaat
     7141 agtctggatg agtccacgtt cgttgcgaag gaaaccttcc ttgtcagcat cgagaatagc
     7201 tacgaggctc acttcaggaa cgtcaattcc ttcacggagc aggttaattc cgaccaagac
     7261 atcaaagaca cccaagcgca ggtcacggat aatctccgtc cgttccaagg tcttgatatc
     7321 cgagtgcatg tacttgacct tgatacccat ttccttgaag tagtcggtca aatcctctgc
     7381 cattttcttg gtcaaagttg tgataaaggt acgctcattt ttttcaacgc gggcattgat
     7441 ttcacccaag aggtcatcaa tctgtcccat agtcggacgg acttccacct ctggatccaa
     7501 gagtcccgtt ggacgaatga tttgctcaat cactgtctcg gtctgttcat tttcatagtc
     7561 accaggtgtc gctgaaacgt aaacaatctg atgaacgtga ctctcaaact cctcccgacg
     7621 gagaggacga ttgtccaaag cagacggcaa acggaaacca taattaacca gcatttcttt
     7681 acgcgaacgg tctccattgt acatgccctt gatttgccct atggtcatat gactctcgtc
     7741 aatcataatc aagaaatcat ctgggaagaa gtcgagaagc gtataaggag gctctccttc
     7801 gctccgtcca tccatgtggc gagaataatt ttcaacccca ttggtatagc ccatctcacg
     7861 caacatttcg atatcatact ctgtccgctg tttcaaacgc tgggcttcaa gcagtttacc
     7921 ttccttttca aagacagcta attgttcttc caactcggcc tgaatctttg caatggcaac
     7981 ttccatgtgg tcgtcattgg tcacaaagtg tgtcgctggg aaaatcgcta aatgatccac
     8041 ttctcccaac acctgacctg tcagagcctc aacttcacga atacggtcaa tttcgtctcc
     8101 aaaaaattct actcgaaagg catgttcatc tcgggaagct gggaaaatct ctaccacatc
     8161 cccacgaacg cgaaatcttc cgcgttggaa atcaatatca ttgcgttcaa actgaatatc
     8221 gaccaagtca ttcaagagtt tatcacgaga aatctctaga ccaggacgga gactaacgac
     8281 actatcagcg tattccttgg gcgaacccaa accatagata caagagactg aggccacgac
     8341 aataacatca ttacgctcca aaagggctga ggtagctgag tggcgaagct tgtcaatctc
     8401 gtcattgaca gaactatcct tctcaatata ggtatcgcta gaagggacat aggcctctgg
     8461 ctggtaataa tcatagtagg atacgaaata ctcaactgca ttttcaggga aaaattcctt
     8521 aaactcccca tagagctgac cagccagagt tttattgtgg gcaataacca gagttggttt
     8581 attgacttta gaaatgacct gactcatagt atacgtcttc cctgttccag tcgcccccat
     8641 cagaatctga gctttttctc ccccctcaat gttatccacc aactgctcga tagcttgggg
     8701 ttgatctcct gatggttgat attttgatac tagtttaaat tgattatctg taatgtgatt
     8761 gatcataaga atcctctctc catgtgctat tcctatttta gcatacttat agtattttca
     8821 cgaagaaaag gatggaccga agtcacatcc tttcattttc tttctttaat ttattagcaa
     8881 gatagacaat cagcagtagt aataccagac ttgtcataat ggaaccttct atgccaaaag
     8941 aaccacctga tagccaatct tgattgcctt gtggtaaaaa ggtcatcaga gacgttcctg
     9001 acggttgacc actaactaaa atcccaaaga gattaccctg agcaaaattc caagcaccat
     9061 gaatacctgc aacaccccaa actgtatcag ttttgagaag gtaaagagcc atggcaactc
     9121 cgaataaaaa gagatttact agagatagag gggtgaggcc agaattgccc atatgaagca
     9181 gggtaaagaa caggctagat ataagaatag ctagttttag attggttctt gaggccaatt
     9241 gaggaagtag ccaagcacgg gccaccactt cttctgctgt cccctgtaaa atccaaaatg
     9301 ggatagtaaa gacgacaaag gcaagagaat aaggattcaa gtgaatggat tccaaacgat
     9361 attgacctaa gaccaccaaa cctaacaagg tcagaagaaa aagtgccaga cctagactaa
     9421 atcctttcag aagattgctg aggaaattct ctctataaaa tcccaaggtt cgaataggtc
     9481 ttttctcaac ttttcttgtc catctgaaca cagtgttaag aataaaacca aaggccagta
     9541 atcctaaaat taaacgaaag tcacttgttt tatccgtcaa gctctgatgc aaggtctgca
     9601 agtagcttgc aagattttga ccagcctctc caaaatttct agcaagtccg atgagagcta
     9661 acaagccaat accatacaaa gtaaaagcca caaactctcc tatgaagaca aaaacaaagg
     9721 ctaacaaggg gcttgtgtaa atgtttaaac tcatttttga agcttggaag tctttaaata
     9781 ttcttttgtt cttcatatcc ccgtcctctt ttcttctata tatactatta ttatagcact
     9841 ttttaatagc aattcaaaga aaggaaaaaa tcaatgttat attttctgac acgaaaaata
     9901 taaaaatttg ccttttttta ctttttctga tataatgaga gaatattcgg aaaaggagac
     9961 taaaaatgaa gaaaaaattt ctagcatttt tgctaatttt attcccaatt ttctcattag
    10021 gtattgccaa agcagaaacg attaagattg tttctgatac cgcctatgca ccttttgagt
    10081 ttaaagattc agatcaaact tataaaggaa ttgatgttga cattattaac aaagtcgctg
    10141 agattaaagg ctggaacatt cagatgtcct atcctggatt tgacgcagca gtcaatgcgg
    10201 ttcaagctgg gcaagccgac gctatcatgg cagggatgac aaagactaaa gaacgtgaaa
    10261 aagtcttcac catgtctgat acttactatg atacaaaagt tgtcattgct actacaaagt
    10321 cacacaaaat tagcaagtac gaccaattaa ctggcaaaac cgttggtgtt aaaaacggaa
    10381 ctgccgctca acgtttcctt gaaacaatca aagataaata cggctttact attaaaacat
    10441 ttgacactgg ggatttaatg aacaacagct tgagtgctgg tgccatcgat gccatgatgg
    10501 atgacaaacc tgttatcgaa tatgccatta accaaggtca agacctccat attgaaatgg
    10561 atggtgaagc tgtaggaagt tttgctttcg gtgtgaaaaa aggaagtaaa tacgaacacc
    10621 tggttactga atttaaccaa gccttggctg aaatgaaaaa agatggtagt cttgataaaa
    10681 ttatcaagaa atggactgct tcatcatctt cagcagtgcc aactacaacc actctcgcag
    10741 gattaaaagc tattcctgtt aaggctaaat atatcattgc cagcgattct tcttttgcac
    10801 cttttgtttt ccaaaattca agcaaccaat acactggtat tgatatggaa ttgattaagg
    10861 caatcgctaa agaccaaggt tttgaaattg aaatcaccaa ccctggtttt gatgctgcta
    10921 tcagtgctgt ccaagctggt caagccgatg gtatcattgc tggtatgtct gtcacagatg
    10981 ctcgtaaggc aacttttgac ttctcagaat catactacac tgctaatacc attcttggtg
    11041 tcaaagaatc aagcaatatt gcttcttatg aagatctaaa aggaaagaca gtcggtgtta
    11101 aaaacggaac tgcttctcaa accttcctaa cagaaaatca aagcaaatac ggttacaaaa
    11161 tcaaaacctt tgctgatggt tcttcaatgt atgacagttt aaacactggt gccattgatg
    11221 ccgttatgga tgatgaacct gttctcaaat attctatcag ccaaggtcaa aaattgaaaa
    11281 ctccaatctc tggaactcca atcggtgaaa cagcctttgc cgttaaaaaa ggagcaaatc
    11341 cagaactgat tgaaatgttc aacaacggac ttgcaaacct taaagcaaac ggtgaattcc
    11401 aaaagattct tgacaaatac ctagctagcg aatcttcaac tgcttcaaca agtactgttg
    11461 acgaaacaac gctctggggc ttgcttcaaa acaactacaa acaactcctt agcggtcttg
    11521 gtatcactct tgctctagct cttatctcat ttgctattgc cattgtcatc ggaattatct
    11581 tcggtatgtt tagcgttagc ccatacaaat ctcttcgcgt catctctgag attttcgttg
    11641 acgttattcg tggtattcca ttgatgattc ttgcagcctt catcttctgg ggaattccaa
    11701 acttcatcga gtctatcaca ggccaacaaa gcccaattaa cgactttgta gctggaacaa
    11761 ttgccctctc actcaatgcg gctgcttata tcgctgaaat cgttcgtggt ggtattcagg
    11821 ccgttccagt tggccaaatg gaagccagcc gaagcttggg tatctcttat ggaaaaacca
    11881 tgcgtaagat tatcttgcca caagcaacta aattgatgtt gccaaacttt gtcaaccaat
    11941 tcgttatcgc tcttaaagat acaactatcg tatctgctat cggtttggtt gaactcttcc
    12001 aaactggtaa gattatcatt gctcgtaact accaaagttt caagatgtat gcaatccttg
    12061 ctatcttcta tcttgtaatt atcacacttt tgactagact agcgaaacgc ttagaaaaga
    12121 ggattcgtta atggcaaaat taaaaattga tgtaaatgat ttacacaagc actatggaaa
    12181 aaatgaagtc ctaaaaggaa ttacgactaa gttctatgaa ggagatgttg tttgtatcat
    12241 cggtccttca ggttctggta agtcaacttt cctccgtagc ctcaatcttt tagaagaagt
    12301 cactagcggt cacatcactg tgaacggcta tgatttaact gaaaaaacaa ccaatgttga
    12361 ccacgtccgt gaaaatatcg gcatggtatt ccaacacttc aacctcttcc ctcatatgtc
    12421 tgtattggac aacatcacct ttgctcctat tgagcacaag ttgatgacta aggaagaagc
    12481 tgaggaattg ggaatggagt tgcttgaaaa ggttggacta gcagataaag ctaatgccaa
    12541 tccagatagc ctatcaggtg gtcaaaaaca acgtgtggcc atcgctcgtg gcctagcaat
    12601 gaatccagac atcatgctct tcgatgaacc aacttctgcc cttgaccctg agatggttgg
    12661 agacgtactt aacgttatga aggaattggc tgagcaaggc atgaccatga ttatcgtaac
    12721 ccatgagatg ggatttgctc gtcaggttgc caaccgcgtt atctttactg cagatggcga
    12781 gttccttgaa gacggaacac ctgaccaaat ctttgataac ccacaacacc ctcgtctgaa
    12841 agagttctta gataaggtct taaacgtcta aactcaaact gtaaggattt ccttgcagtt
    12901 tttctacctc gtattggaat ttttgatttt tcggaaaatt atgttagaat taagtttatg
    12961 aaatgaggtt tcctcatacc tagcaagact aggaataaaa atagaaatta ggtagctaga
    13021 tgtcatctaa ggttattgtt acaattttcg gtgcgagtgg agacctggct aaacgcaagc
    13081 tctacccttc cctttttaga ctatataaat ccggcaatct ttccaagcac tttgccgtta
    13141 ttggaactgc ccgtagacct tggagtaagg aatattttga atctgtagtt gtcgagtcca
    13201 tccttgattt ggcagatagt accgagcaag cccaagaatt tgctagccac ttctactatc
    13261 aaagccatga tgtcaatgat ttggaacatt atattgcttt gcgtcaatta caagctgagc
    13321 ttaatgaaaa ataccaagct gaacacaata agctcttctt cttgtctatg gcacctcagt
    13381 tctttggaac cattgccaaa cacctcaaat ctgaaaacat tgtcgatggc aaaggttttg
    13441 agcgcttgat cgttgaaaaa ccatttggta cagattacgc aactgcaagc aagttgaatg
    13501 acgaactcct agcaacattt gacgaagaac aaattttccg tattgaccat tatcttggta
    13561 aggaaatgat ccaaagcatc tttgcagttc gctttgcaaa cttgattttt gaaaacgttt
    13621 ggaacaagga ttttatcgac aatgttcaaa ttacctttgc ggagcgcttg ggtgtagaag
    13681 aacgtggtgg ctactatgac caatccggtg ccctccgtga catggtccaa aaccacactc
    13741 tacaacttct ttcgctcctc gccatggaca aaccagcaag cttcacaaaa gacgagattc
    13801 gtgctgaaaa gattaaggtc tttaaaaacc tctatcatcc aactgatgaa gaactcaaag
    13861 aacactttat ccgtggacaa taccgctctg gtaagattga tggcatgaaa tacatctctt
    13921 atcgtagcga accaaatgtg aatccagaat caacaactga aacctttaca tctggtgcct
    13981 tctttgtaga cagcgatcga ttccgtggtg ttcctttctt tttccgtaca ggtaaacgac
    14041 tgactgaaaa aggaactcat gtcaacatcg tctttaaaca aatggattct atatttggag
    14101 aaccacttgc tccaaatatt ttgaccatct atattcaacc aacagaaggc ttctctctta
    14161 gcctaaatgg gaagcaagta ggagaagaat ttaacttggc tcctaactca cttgattatc
    14221 gtacagacgc gactgcaact ggtgcttctc cagaaccata cgagaaattg atttatgatg
    14281 tcctaaataa caactcaact aactttagcc actgggatga ggttggtgcg tcatggaagt
    14341 tgattgaccg tattgaagag ctctgggccg aaaatggtgc cccacctcat gactataaag
    14401 ctggaagcat gggacctcaa gccagctttg acctacttga aaaattcgat gccaaatgga
    14461 cttggcaacc agatatcgcc tatcgtcaag atggtcgttt cgaataaaaa aatcctgcaa
    14521 gtttgtacct tgcaggattt ttgcttctga ttagattaag ccttccaaga gacctttcat
    14581 aaagttttct gagttaaact ctccaatatc atcgattttt tcaccaaaac caatcaattt
    14641 tacaggaata ttgagttctt cacgaatggc tagaaccaca cctcctcgag cagttccatc
    14701 aatcttagtc aaaacaattc ccgttaaagg tgtgattttc gaaaattctt tggcctgtac
    14761 tagggcattt tgacctgttg atgcatcaag tgccaagaag gtttcatgtg gtgcttctgg
    14821 cacaacacgt ttgataatac gaccaatctt ttccaactca gccataaggt tatccttatt
    14881 ttgcagacga ccagcagtat caatcatgag aatatcgata ccttcagcca cggcacgttc
    14941 cataccatca aagaccacgc tggctggatc agctttttca ggtccagtta ctactggaac
    15001 atctactcgt cggccccatt cagctagctg agctactgca cccgcacgga aggtatctgc
    15061 tgcaaccagc atgaccttct taccagttcg tttgtagcgg tgggctagtt ttccaataga
    15121 agttgttttc ccaacaccat tcacaccaac aaagagcata actgtcaagt tatcttggaa
    15181 gtggatgctt tcatcgtagc taccatcctt ttcataaagc tcaaccaatt tctcaatgat
    15241 gacacgacga agtgcatcag gtttcttggc attttcaagc ttggcttcgt aacgtagttc
    15301 ctccgttaag ttagaagcga cttggacacc aacatcactc ataatcagca gttcttccag
    15361 ttcctcgaaa aattcttcgt caacagagcg gaagttagca aagaaggcgt tcaagcgagc
    15421 accgaagccc gtacgagtct tcttgagact gcggtcatat ttttcctgaa cagtttcttc
    15481 tgtttgaggc ctttctggtt caagaacttc agaattattt tcttctatag ttccttcgtg
    15541 ctcaagcttc tcttcctctg gtaattcttc tgagtttggt aattcttcta tttcttcttg
    15601 agaaacccct acagctggct ctgaatcctg actttcttca actgtgtctt ggatttcctc
    15661 ctcttggaac acagcttgtt caacaatttc aacctctgct tcttcctgag gaacttcctc
    15721 aacttctgtg aaggtaggat caacatcttc agacaaatca agattttcca gagcttcttt
    15781 tacaacttct tcgattttag gttcttcttt ttttccgaat agacggtcaa acaatcccat
    15841 atcttagttc tcctttagca catattcttc gatagcccag gcgacagctt cctcatcgtt
    15901 ggtcatcggc gttactacat ttgcggctgc ctttacttca ggaacagcgt tttgcatagc
    15961 aacaccaaga cctgcccatt caatcataga aaggtcattg gcctcgtcac cacaggccat
    16021 aacttggctt tggttgattc caagatggct gattagtttt gccaaacctg ttgctttatg
    16081 aacattcttt ggtgaccact ctagcaacat ttcacgtgat ttaaagattt catattggtc
    16141 aaacaattct ggagaaatct tctgaatggc tgcatccaag ggttcttgag caaaggcagt
    16201 cacgcatttg ttgtaggtca tttgactaga caggtcttca aagtcaactg gaacaaaagt
    16261 caaagctgga ttgaatttgg cataaagact ttcttggtcc gattggattt gataaactgt
    16321 tccttctgag atggcatcaa gtggcagtga taatttctct gttttctcat acaagcgtgc
    16381 cacatcagca tatgaaaaga ctgttttatc aaggatttca cctgtatttt tctgaaccaa
    16441 accaccatta aaagtaatgg tatactcatc ttcctgaccg tcagtcccta actcatggag
    16501 aaagaagtcc atggctttta agggacgacc agttgtcaat acgaccttga taccacgatc
    16561 acgcgcagct ttcaaagttg ccttggtgcg atccgtcagc cttttatcag tagtcagcaa
    16621 ggtaccgtcc aagtccaatg cgattaattt tatatctgcc attataagcc ctccatataa
    16681 gctataaccg actggtcctt atggtgacca atcacagtct ttgctaattc taaaatctct
    16741 ggtcgtgcat tttcaggagc tacaggatgt cccacaacct gcatcatatg taagtcatta
    16801 agattgtctc caaaagccat gacctgatcc attgtgatgc caagtttttt agctaattca
    16861 acaatagcta cacccttatc gacatagtcc agaacaatat caatagattc aaagccagtt
    16921 gtcatagcct tgacaccagg gacattatca ttgacccaag cttcaccagc ttctagcgtt
    16981 tcttctgtga agttggttgt aaatttgaaa atgtcatctg tgatatcttc caaactcgct
    17041 actttttgga tattttcatt ataatgctga ctcactttca aataggtctc atcaaccgta
    17101 tctagaacat atgaaccctt cttacccgtc aagagcagtt tattgatatc tatataaggt
    17161 gacgttttca gcttttcaaa agttgccaga taaaagtcac gagacatagt cgcttcatac
    17221 aagtcctgac cttgatactc taccaaactg ccattttccg cgatgaaaat aatgtcatca
    17281 cgaacaccag caaataattt ttccagagac agaaatcccc gacccgaagc caccgcaaag
    17341 taaatccctt tttccttgta ggaaaccaag agagacttga ggcggtccat atcaaagcgc
    17401 ccattctcat ctaggaaggt tccgtccata tccgttgcta ctagtttaat tgtcatcctt
    17461 caatactttc taaatctttt aacttaactg aaacaatctt tgaaacaccc gattcttgca
    17521 tggtcactcc atagatggaa tcggccgctg ccatggttcc cttacggtgg gttacgacga
    17581 taaactggct gtccttgtca aagcggttga ggtaatcccc aaaacgttta acattggctt
    17641 catccagcgc agcttccacc tcatccaaga tgacaaaagg aatggtcttg acacgaataa
    17701 tggagaaaag caaggcaaga gccgataggg ctttttcacc accactcatg aggttaagcg
    17761 actggatttt cttacctgga ggttgaacag aaatctccac accagctgtt aaaaggtcgc
    17821 cctcagtcaa tatcaagtct gcctgacctc cgccaaacat ctgcttgaag gtcactttaa
    17881 aggactcacg aatagcttca aaggttgatt taaagcgttc cttaacctca tcattcatct
    17941 ttgtaatggt ttcaaggagc agatttttcg ctgacaaaat atcatctcgc tgactattta
    18001 gaaagtccag acggttgtga acttcttcgt accggtcaat agcttctata ttgacaggac
    18061 ccagtgagcg aatagccttc tctaaatcct taacttcttg ctctgccaga ttgaggtttt
    18121 ccaattcatg cgctttttct agagcttcag tatagctaat ctggtactgg tctgttaatt
    18181 gactttgtag atggcgcaag cgctcgctga ccttttcttt cttagcttca gcacgtgttt
    18241 gcttgcgaat ccactcctca ttctgctggc gagcctgatc caaatgacta gcaatatcat
    18301 ccagctgacc ttctatatca tccaactcaa actgtttgcg aatcaaacct tgttggaggt
    18361 tcgttttctg agttttggat tcttccgcct gttgactgag caattctgta tcaaccttct
    18421 caagattgtc aaccttttct tgaagaaggc gctggatttc ctcttgttca aaatcaagat
    18481 tgtccaattc cttgcctaag cgttcaatat cagcaacttc ataacgtttt tgcccttgca
    18541 gttctgtctt aagcaaacga gcttgcgcta gctcttcctg caagttttga tagcgttctt
    18601 ggatggcatt tttattagac ttaatctctt caatctcagc ttccagattt tgcttgtcac
    18661 tggcgattgc agcaagacgc tcttggcatt tttccttatc cgcttgccaa tctccctcgg
    18721 aaagacgatc tatttcctct tcttggagtt tccaaagagt ttccagttct tcaacttgct
    18781 gactagtttg ctgataagcg agggacaagc cttgctcctg aatacgtgcc tgctctcctt
    18841 gagatttaat agcttctaat gactcggtca atctggccat ctcatcttgc aaggtcttca
    18901 aagccacttc ttctgaaccc aagcttgctt cttcttcagc aatttctttt tgtaattgct
    18961 ccagttctgg cttgatgaag atgctgttgt tctgacgatt ggctccacct gcataggaac
    19021 cacctgtacg aagctctgtc ccatccaatg tcaccatgcg aacctgataa cgaacttgtc
    19081 gagcagcttc acgcgcatgt tctacggtat caaagatagc cgtcgtagct agcaagttct
    19141 tgaaaatggc ttccagtcta gtatcaaaag tcaccaactc atctgccatc ccaaggaaac
    19201 ctgggcttac agcgatagca tcttggttct gactagaaat cgtacgcgcc ttaatagtgg
    19261 tcaaaggaag aaaggttgca cgaccggctc tgtttcgttt gaggaaatca atagctttgg
    19321 ttgccgactc ttcatcttct acgatgatat gctggctact tgcccctaag gcaatctcta
    19381 gggcagtttg ataataaaca tcaaaggtca gatgctcact gactgcacca ataatcccac
    19441 ctaggcgatc tttttcttgg agaacactct taacacctgc ataaaagttg ctatgatttc
    19501 tcaggatatt ttccaaactt tgagctctgg cctgcttgtt tttgagacta tccagacggt
    19561 caaagagttg agtttgttga gcttgatagg aagttttctg ctcctcttgc tccttggcaa
    19621 tagcttggta gtcagccaat aatttctgaa cctgctcctt ggcagtttca agctcttcct
    19681 tttgctgact agccttctct ttagctatag ctaattgctc tttcagcttt tctagttgat
    19741 ctgcttgttt ttgagaaagc tgacgactat tttccaactc attctcaata cgggtcaact
    19801 ggtttgagac atccgcttct tcttgtaaaa gagctacaaa gcgttcacgt aagagctcaa
    19861 tcatctgatc aggatcgtct gagaaagcca gcaattcagc ttctaaacga ttgagttttt
    19921 gattattttg gactagattt ccctctaaca gagctaaaga gctttcttta tcagactttt
    19981 ctttgctgag tgaatttctc ttatcctcca aagcagccaa acgggcttgt gcctcctgtt
    20041 gattcagggc cacttgctcg gactccagtt tcgatagggc taattttctt tctaaatcac
    20101 taatcagact agtcaagtcc atcaaactgc cttggtcttt ggccatttca gcctgtaaat
    20161 cttggcgttg ctttttaaga gtttgatttt cttcttctaa tttttcacgc ttttggtaat
    20221 aactcatcaa gagttcttga acctgagcca actcttcttc tgtcgactct agttctgcct
    20281 tattttcctt gatttgagca accagaacgt ctaaataaat agccttacgt tgtccttcca
    20341 agtctaaaaa cttacgggca ttctcagctt gcttctcaag aggcttgatt tgattatcca
    20401 actcgtagat aatgtcctct aagcggtcca gattatcctg agtttgttgc agtttactct
    20461 cagtttcttt tctacgagtc ttgtatttta aaactcctgc agcttcttca aaaatagccc
    20521 ggcgttcctc aggcttagaa ttaaaaatct cctcaacctt gccttgggaa atgatagaga
    20581 aggaatctcg tcccaatcca gtatccaaga agaggtcatg aatatcacgc agacggactt
    20641 tcttgccgtc aatcttgtat tcgctatctc cactacgata gatatggcgt tccaccctga
    20701 tttcttgacc tgcatccttg ataaatccgt catgattatc cagagtcaca actacagaag
    20761 cataattgag cggtttgcga ctttcggttc cagcaaagat gacatccggc atcttgcccc
    20821 cacggagact cttgacacta gactccccca aagcccaacg cagactttct gtaatattgg
    20881 actttccaga tccattgggt ccaacaactg ccgtcacacc ttggtcaaaa acgaccttgg
    20941 tcttatcagc aaaagacttg aacccctgaa tttcgatttc ctttaaatac atgaatccag
    21001 ccccttctca acggcatttt tggcagcttc ctgctctgct aatttcttag aacgaccttg
    21061 gccttgaccg atgctcttac cttcaacaag aacttctaca tcaaagacct tatcgtgagc
    21121 aggccctgtt tcagaaatca cctgataacg aatagccaca tcaccattga cctgaagcaa
    21181 ctcttggaga tgggttttat agtctgtaat catctcaaac tcgcctgctt caaccttagg
    21241 aatcatgact tgatagataa attccttgac cttggccaca tccttatcca aaagaagggc
    21301 accaagaaag gcttcaaagg catcaccaag aatggtgtca cgattgcgac caccagattt
    21361 ttcttcccct ttacccaact tgataaactg gtcaaactgg caatcacgcg caaaaccagc
    21421 taaactctcc tcacggacaa tcatagcacg gagttttgat aggtcacctt caggcttttt
    21481 aggatatttt ttatatagat attctgaaat caataactgt agaacagcgt ctcctaaaaa
    21541 ttccaagcgt tcattgtgtg aaatttttaa gaggcggtgc tcattggcat aactcgtatg
    21601 agtaaaggca gtttccagta aatttttgtc tgcaaattcg attgcaaaat gattctttag
    21661 tacagtttgt aattctttca taccaacctc tttctaactg ataatagtcc tttttattat
    21721 atcaaaaaaa gccccctgag tcactctaaa acgggactgg aaagcatttg ggaattcttt
    21781 agacagagat tctcagtttt agcgacaaat ttgggtcagg ataaagaaaa aagccctatt
    21841 aaaggctttt taggatgttt acatccaccc tgagggaatc gaacccccat ctcaagaacc
    21901 ggaatcttac gtgatatcca ttacactaag ggtggaaact tgttttatta taacagaaat
    21961 ttgctctaat aacaagtttt ttggtcaaag accccgtctt agtgggaagc atccccattc
    22021 cagatggagt ttttcacgat cacataatca acgtgtttaa ggtcagcaac ctgacgtcca
    22081 cctgcataag aaatagcact ttgaaggtct tgttccatct cagttaaagt gtcttgcaga
    22141 tgacctttag caggaagcaa gatacgtttg ccttccacat ttttgtaagc acctttttga
    22201 tattgtgagg ctgaaccata atattctttg aactgttcac catcgacttc aatcgttttc
    22261 cctggacttt caatgtgtcc tgcaaagagg gaaccaatca tgatcatgct agcaccgaag
    22321 cggatagact tagcaatatc accgtgagta cgaattcctc catcagcgat aatcggttta
    22381 cgcgcagcct tggcacacca gcgtagagca gccaactgcc aaccacctgt accaaaacca
    22441 gtcttaacct tggtgataca aaccttacca ggaccgattc cgaccttagt agcatccgca
    22501 ccagcatttt ccaattcacg cacagcttct ggtgttccca catttccagc aatgacaaag
    22561 gtatctggca attctttctt gatgtgttga atcatagaaa tcacgctatc cgcatgacca
    22621 tgagcaatat caatagtgat atactcagga gcatcagcct tgagctggct aacaaaatca
    22681 tactcataat ccttaacacc gacagagata gaagcaatga gcccttgatc gtgcattcgt
    22741 ttaataaaag gaatgcgtcc tgcctcatca aaacggtgca taatgtagaa gtaaccacct
    22801 ttagccagtt gctctgctac attttcatcc aaaatcgtct gcatattcgc tggcacaaca
    22861 ggtagtttaa aggtgtgatt tcctaaagtg acacttgtat ccgcttctgc acggctttta
    22921 atgacacatt tatttggaat caattgaata tcttcgtaat caaaaattgg aaattcattt
    22981 aacatatcga tgtctcgttt cttttgtaat gacctaccta tgctcttgca tcactacgcc
    23041 ttttccgacg tttccttaat ttattataaa ccaaagtaca gtttttgtca aattatttta
    23101 tgaattaaaa tatatcgttc gggttttact tgtgttaaaa ataaaagaaa gaggggaaat
    23161 tattttctcc ccacttcttc atcaataatc gctttaaaat tttcttctga attttccatc
    23221 attttacaaa atgtactata gaatgaggca ttctgaggga ttcgaataga ccacttcttc
    23281 aattgagctc catagccagc tacttttcct atttcactat ttactgactg ctccatacta
    23341 ggaaaaatca gtccagcctt ctcagctttt aaaatataag aataggaaat cagctggaat
    23401 aagtcctcac ggttgattcc tttttcagtc aattccagtt ttttatattt tgcatctaga
    23461 acaatctttc gttctctgtc ataaaaatct ggatatactt ttcgtttccc aacagaaaat
    23521 actgaaattc catccgtctt atccttattt ctgggatgta caaaaccttt tggcaacaag
    23581 gtgtaaacat actcttccca aagccaggca acatcaaaga gaataccata gattttttga
    23641 tcttgatacc ctaaaccgtg cttttcttgg tttaggatca tcagacaaag ttcttgtaag
    23701 tttctgtact cgtgaaagta tgcatgacgt ataggtttag attgatttcc ccgaataatc
    23761 ttagcacgat cagctagttt ataagagggc gttacacgca cgatttcaga tacgttttca
    23821 cgactagttg agagattatc tagtacccct tgaccaatgc ttttctgatt cttaatgtat
    23881 tcaatagtgt gacggaccaa ctgcatgagg ggattatcat aggtgaactc tctcgttgcg
    23941 taggcaatat ttcccgtgaa aggaagattt ttcttgagat ggtttcttac atcaatcact
    24001 cccttaacat gactgtcgtt atgagaaaat cgatgatatt ccttataaag accttttcga
    24061 atagcagctt gtagatactt gggaaagaga tacaccaaaa gttgataaag cctctcttca
    24121 cgagacaaag caacatctaa actagtgaga ttgatataaa gaaccttgtt taagagataa
    24181 tgcaaaaaat ggtcattact ctcatcagaa aatcgtgagg aaatcgttaa tctttcctga
    24241 ccatatccaa gaaaaccaat cacgttccct gtcttgattt tctgattgac tgtttcaaaa
    24301 atcttttggt ccttatccaa atcaggagta tgagtcaaat catttggaaa aatgaaaata
    24361 cgttcatctt gggatagact ttccaaggtt ctgtctaaaa gaagattgct tagtttagga
    24421 tattcttcaa caaatttttc tttaataatc ttgtgttgat tatcagtaat ccgcatcatc
    24481 gttttcatcg ccttcattgt catcagctac tgcctgatct ttttgctcat tatttgtcag
    24541 ttcaaatgct tttttcaaag tttccaaagt ttcaacctca tcataagaac ctcgcaagta
    24601 gtcttctagg agaggcttaa tataatcaga ccagagtaat tcatagtcaa aatctacatc
    24661 cttcaactta agaaaataac ttggtccaat atgataatga ctgtttaatt cctgaacatt
    24721 ttcgatagca gcgttcaagt ttcttagacg aatttttgct tcttctgcat ggatattcag
    24781 ctctttatcc aacatgccaa cttgaccctc ggcagtaact tcaacaaaac gaaaacgacg
    24841 acgcatagca aaatcaaagg tatccactga acgatcaatg tcattcatag ttccgatgat
    24901 gtagacattt tcggggatat agaacttttc atcagtttcg tgtagatttg catattgggt
    24961 agaaacactt cctttttcac cacgatagcc agggtcgata gagaaaaaga gttcgccaaa
    25021 aatcttagaa atctccccac gattgatttc atcgatgatg aagacgaatt tcttatcagt
    25081 atcaatttct gttggggaaa catagtcttt caaaccaaat ctctttctca atgtttctag
    25141 gacagttttt ccaccacttt tgtagtattc ttgcttatta taatttttat ctttatacaa
    25201 ctcgtaaaca tatttgctag gtagtgacca tcctggaaca ccactatcat aatttactga
    25261 caaattttgt ctactattaa cagataagta agatgttttt gttatatatt ctttttcttc
    25321 agcaacattt atatattcta agtaagaatc ccaagcctca tcaaaattat cttgtcctcc
    25381 aatcaattgg gtttcttttg ctttctgaca aaaatcttta aaaataccgt cctgtagcct
    25441 aaactcaata gctccatccc catttgatac tggtcttaaa ccttctacaa aatccgtata
    25501 atcataggat gggtgaaatt gtacaaatcc gatttggtct tcgttgccat ccgttaattc
    25561 tttggcaatt tctttagcaa gataagtctt tcctgtgcca ggagcaccac ggaggatgag
    25621 gtttttggat tgtaataaga tattcttata ctcgttgata ttttctgaca tgtttatctc
    25681 ttccttttct gattctctat aaaaactagt gaaattatca taaaactctt ttaaaatatc
    25741 gttaggttca gcagttgatt ccaactctaa gtccttgaca aagtatttat aatctaaatc
    25801 ttcatctcga ttattactat acctttttac tattttaaat tctgtgagtt taaatctctg
    25861 aaaaccacat cttatattta tccatgagtt atccatgtca ctcagccgat aaccaaagta
    25921 aggtgattta atatatccat taccactctt tggaccaaaa tgacctgtgt taagcatttc
    25981 aactttgtac agaataccct caatagtcag agcagggtaa atatgttcag ctccatctaa
    26041 tttttgagaa cgtttaattt ctatattttt tgaattatag atatttgctt gattcacaaa
    26101 t
//
LOCUS       DAVKBC010000027        26003 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVKBC010000027 DAVKBC010000000
VERSION     DAVKBC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26003
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.027"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(102..377)
                     /locus_tag="VWX64_001315"
     CDS             complement(102..377)
                     /locus_tag="VWX64_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU9190782.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(484..1323)
                     /locus_tag="VWX64_001316"
     CDS             complement(484..1323)
                     /locus_tag="VWX64_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9190783.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1465..2313
                     /locus_tag="VWX64_001317"
     CDS             1465..2313
                     /locus_tag="VWX64_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9190784.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILGWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2406..3323)
                     /locus_tag="VWX64_001318"
     CDS             complement(2406..3323)
                     /locus_tag="VWX64_001318"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU9190785.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3761..3966
                     /locus_tag="VWX64_001319"
                     /pseudo
     CDS             3761..3966
                     /locus_tag="VWX64_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4277..4570)
                     /gene="rpmA"
                     /locus_tag="VWX64_001320"
     CDS             complement(4277..4570)
                     /gene="rpmA"
                     /locus_tag="VWX64_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU9190786.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4587..4931)
                     /locus_tag="VWX64_001321"
     CDS             complement(4587..4931)
                     /locus_tag="VWX64_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU9190787.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4947..5261)
                     /gene="rplU"
                     /locus_tag="VWX64_001322"
     CDS             complement(4947..5261)
                     /gene="rplU"
                     /locus_tag="VWX64_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU9190788.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5298..5385)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5480..6079)
                     /locus_tag="VWX64_001323"
     CDS             complement(5480..6079)
                     /locus_tag="VWX64_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU9190789.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDIR
                     DKLLTLIAFMMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIGFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSVYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6550..6849
                     /locus_tag="VWX64_001324"
     CDS             6550..6849
                     /locus_tag="VWX64_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU9190790.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7069..8082
                     /locus_tag="VWX64_001325"
                     /pseudo
     CDS             7069..8082
                     /locus_tag="VWX64_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8398..9372)
                     /gene="pta"
                     /locus_tag="VWX64_001326"
     CDS             complement(8398..9372)
                     /gene="pta"
                     /locus_tag="VWX64_001326"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU9190791.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(9416..10312)
                     /locus_tag="VWX64_001327"
     CDS             complement(9416..10312)
                     /locus_tag="VWX64_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9190792.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(10309..11127)
                     /locus_tag="VWX64_001328"
     CDS             complement(10309..11127)
                     /locus_tag="VWX64_001328"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU9190793.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(11111..11782)
                     /locus_tag="VWX64_001329"
     CDS             complement(11111..11782)
                     /locus_tag="VWX64_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU9190794.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            11910..12479
                     /locus_tag="VWX64_001330"
     CDS             11910..12479
                     /locus_tag="VWX64_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU9190795.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            12592..13551
                     /locus_tag="VWX64_001331"
     CDS             12592..13551
                     /locus_tag="VWX64_001331"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9190796.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            13561..14676
                     /locus_tag="VWX64_001332"
     CDS             13561..14676
                     /locus_tag="VWX64_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9190797.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            14681..15028
                     /locus_tag="VWX64_001333"
     CDS             14681..15028
                     /locus_tag="VWX64_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU9190798.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            15036..15251
                     /locus_tag="VWX64_001334"
     CDS             15036..15251
                     /locus_tag="VWX64_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9190799.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            15334..15975
                     /locus_tag="VWX64_001335"
     CDS             15334..15975
                     /locus_tag="VWX64_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU9190800.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            15993..16682
                     /locus_tag="VWX64_001336"
     CDS             15993..16682
                     /locus_tag="VWX64_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9190801.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(16679..17359)
                     /gene="radC"
                     /locus_tag="VWX64_001337"
     CDS             complement(16679..17359)
                     /gene="radC"
                     /locus_tag="VWX64_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU9190802.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(17402..19693)
                     /gene="pcrA"
                     /locus_tag="VWX64_001338"
     CDS             complement(17402..19693)
                     /gene="pcrA"
                     /locus_tag="VWX64_001338"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU9190803.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(19884..20688)
                     /locus_tag="VWX64_001339"
     CDS             complement(join(19884..20318,20320..20688))
                     /locus_tag="VWX64_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU9190804.1"
                     /translation="MNDEASKQLTDTRFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGVTISR
                     TPLSSEATVMIDATEVQINRPKKQLANYSGKKKFHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKFKSLTVEDKTYNHA
                     LSKERSKVENIFAKVKTFKIFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            complement(21069..21929)
                     /locus_tag="VWX64_001340"
     CDS             complement(21069..21929)
                     /locus_tag="VWX64_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU9190805.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(21945..23222)
                     /locus_tag="VWX64_001341"
     CDS             complement(21945..23222)
                     /locus_tag="VWX64_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9190806.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(23215..23766)
                     /locus_tag="VWX64_001342"
     CDS             complement(23215..23766)
                     /locus_tag="VWX64_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190807.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(23782..25041)
                     /locus_tag="VWX64_001343"
     CDS             complement(23782..25041)
                     /locus_tag="VWX64_001343"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9190808.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         8001 a         5554 c         4604 g         7844 t
ORIGIN      
        1 gaacattcaa ctttttaact ctatttatta ctaaatttca taattaaaaa gcctactgac
       61 caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac agcgtcttta
      121 agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat ttctttacca
      181 gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt accaaaaccg
      241 atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa tacagcttca
      301 actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt agcgatcaaa
      361 tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac aaatataatc
      421 atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat tttatttatt
      481 tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt gagtttgaat
      541 aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta agctttcttt
      601 catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg ctacagcacg
      661 ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag ttccacgacc
      721 tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga tattgagaag
      781 ggagctcaac aagccagtta cacggccaat tcgtccacct ttgacaagat tttccaaagt
      841 tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag ataaaattgc
      901 ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga atttcagggc
      961 ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc tagcaccttg
     1021 gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa gaatctggcc
     1081 accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg gctgacttgt
     1141 tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt ctttcaaatc
     1201 cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg taatatctaa
     1261 ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct taatttttgt
     1321 catagtatca atctttctat tttaggattc agattggttt ccttacttct aattatatca
     1381 aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt tgatataatc
     1441 aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt taccatttta
     1501 ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca tcatctcttt
     1561 gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat ccctgtttcc
     1621 ctcatgaacc tgctgattaa tattcccctt ttcatcctag gttggaagat ctttggagcc
     1681 aaatccctct attctagttt actaggaacc ttagctttgt ccggctggtt agcttttttt
     1741 gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc ccttatagcg
     1801 ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac aactggcgga
     1861 actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg aaaactgctc
     1921 tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga tttgagattg
     1981 gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt gattggtgaa
     2041 ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca acttgctaag
     2101 gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg ctactatagt
     2161 aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt gaaaacgaag
     2221 gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc ccatgaaatc
     2281 ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg acctcaaaag
     2341 ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt tatttactca
     2401 agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc cactaattgg
     2461 tcaactgagt caaatttggt catatctcga atgcgatcaa gccaataaac catgacggtt
     2521 tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc ttcttctcca
     2581 tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct ttgaatctca
     2641 acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag cactaaattc
     2701 gctgtcggat aaccaattgt acgaccacga gcattaccat gaactaccat acctcttgat
     2761 ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa aatagcttga
     2821 cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac aatgataact
     2881 tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc aaatgtataa
     2941 tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc aaagaattct
     3001 tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc ttctacacct
     3061 tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa caaatctgga
     3121 tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac gataggcaat
     3181 aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc cttatgtatg
     3241 ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc tttttggttt
     3301 tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta tttctggaac
     3361 agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa aggcacttta
     3421 ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg taggacatct
     3481 tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc atactatgct
     3541 tatgtatgaa aaagcaatgc aactaactcc tgagaacttt aaattactaa ttggtgccga
     3601 aaaggtagaa tttagaatcg aggtacacct atggctgtaa aatttacaaa atgagacaac
     3661 ttgggcaaga tgtttgaaga atttcctaaa ctccctgatt tgaagcaagt cactttccct
     3721 gatgacaaag aaaaaagcca aagcaataaa gaaaaactag atgactgctt tccaacaact
     3781 cccatctagt gtgcttcaga ctgggctatt tttctttcca tctgttagct tggattctca
     3841 gaccgtttca gctaaagaat atcttttcct ttatcagaag gaacggctca agccattcag
     3901 acaagtgaag ggacgacaag ccaatatttg aaaccaggta gcagttctta tagtcaattg
     3961 aaataaaatc tgaagaaatc gagtaggaaa cttaaatcaa tttttagcag tgttctattc
     4021 cagattcata ctcaatgaaa attaaagtgc aaactaggaa gttagccgca ggctgtactt
     4081 gagtacggca aggtgaaact gacgtggttt gaatttgatt ttcgaagagt atcaatccac
     4141 tatacatatt aaaaagtatg ggtaccaaaa caaaaaaaca ggctctccga aaactcggaa
     4201 agccttattt taagctgttt ctagcttcct cacctttaca tttcaaggtt cgggataaaa
     4261 ggttcaatgg acctttttat ttagcgattg ggtaaacaga aacttgtttt ttatcgcgtc
     4321 ctttacgttc aaagcgtact acgccttcaa ctttagcgaa caaagtatcg tctccaccac
     4381 gaccaacgtt tacacctgga tagatgtgtg taccacgttg acggtaaagg attgatccac
     4441 ctgttacagt ttgtccgtca gctgctttag ctccaagacg tttcgcttgt gaatcacgtc
     4501 cgtttgatgt agaacctcca ccttttttgt gggcgaaaag ttgcaagttg ttaagagtca
     4561 tttttaacat aatgttttcc tccgtgttag ttttctgtga taactctggt ttggacgaac
     4621 tcagaagagt tctccgataa gtttgccata cctaagaaaa atgattcaaa gaataactgg
     4681 gtcatttctc tctggtgtga aggaagatct tttggtattt caaccatcag atagccacct
     4741 tcatcttcgt ttaattctag gattggttca tagcctgcaa atttctcaat agaattgata
     4801 aagttaatgg caagcgtaga aaccgatgca cacacgacat ctaagccgta ttcgccactc
     4861 tcggcgtgtc cagtaatttc cgcactcctc agctcgccat cttcggctct ctcaaagact
     4921 gcttgtatca tgtgttctcc ttaaaattaa gcgttaattg cgttgatgac aacttttgta
     4981 tatggttgac ggtgaccttg tttacggtgg ctaccttttt taggtttgta cttgtaagta
     5041 acaactttct tttgttttcc ttgtttttca acagttccaa ctacagtagc tccagcaaca
     5101 agtggagttc cgacaacagt gttttcacca ccaacaagaa caacttcgtt aaaagtaact
     5161 tcttgaccag cttcaacgtt caatttttca atgtaaactg cttgaccaac ttcaacttta
     5221 acttgttttc cgccagtttt gataattgcg tatgtgctca ttatgcacct cctatgattt
     5281 ttatgggttt ccccgatttt tttgtgaaga ctcgcctagc atcgtgggac aaaccactta
     5341 aacttgaata atcaagcaac gatgttcgtg cggttgcaca ggatcgtgca tagtcaactc
     5401 ttcaagtgta gcatatttcc tattttctta caagtaataa cacctaaaat caagcttttt
     5461 cttttacttt tttctgccac taggcaaaaa gcatactgag ataaaaaatg ctcatcataa
     5521 taggaacacc aagaatggtc ttttcatgat agaaaatcgt caaatagact gaaaagacaa
     5581 cgccaaggac aaaactacta agcaggctaa caaatatgaa cccttcacgc aaaaaaggag
     5641 tgtgcttagt tcggaaataa tctccaaaag ctagcattgt tcgtttgata ttccctgtca
     5701 taaaggcatt attgtaggca atacccgaaa cctcaccaaa agcagttgtc accagtccca
     5761 tacagaaggc caagggcggc actagataga tattatctac agtttgtggc acaaaaccaa
     5821 taattattga taggattgct aaaggaatca aggacagaat agattttttc acaattctca
     5881 atttttcctt ataaatcgtt aataaaaaga ctcccatcat aaacgctatt aaggttaaaa
     5941 gcttatccct aatatccgaa acattatttt gtatgagctc taccgaaaga aagacaacat
     6001 ttccagcttg tccagctaca agggtattcc cgcgaacaat aaaagtgtaa gcatccacat
     6061 atccagcaca aaacgtcaaa aaagtgctaa ccttttagac tgacgtgata tttttcttat
     6121 aggtaataac ctcattttcc ctcccattgt attttctctt agaaatattg taccattttc
     6181 tttctaaaaa atcgtaggct accatttaga ttttactatt agcataaaaa taataataga
     6241 caactattta tccaaaaata gatagaggta acatgtttgc aaacaaagca tacgaacctt
     6301 tagtaaaatc atttccatga aactagaata gagcccctct tagcaaaaat cattatttta
     6361 atttatttct aatcactcct tgacataaat aactctcacc aataaaagac tatgtcttaa
     6421 aaaaatggta taataaaatc aatacttggg cttgatggct atgctactaa taacaattag
     6481 gagagaaaat caggcacttg ttaacaacaa ggattatccc cttgagatga aaggaacttt
     6541 agaaatctta tgatgaacat gcaaaacatg atgcgtcaag cacaaaaact tcaaaaacaa
     6601 atggaacaaa gccaagctga acttgctgct atgcaatttg ttggcaaatc tgctcaagat
     6661 cttgtccaag caaccttaac tggcgataag aaagttgtca gcattgattt caatccagct
     6721 gtcgttgacc cagaagacct tgagactctt tctgatatga ccgttcaagc catcaactct
     6781 gctcttgaac aaatcgatga aactactaag aaaaaactgg gtgctttcgc tgggaaattg
     6841 ccattctaaa aacaaggagc tagaacaatg cttgtcgata acaaaggcta agaaaggtgc
     6901 aaaaattata aaaaacgcat agtatcaagc aacctaaaac tttgggctct ataatatttg
     6961 tagtgggtaa atcccctatg gatattatgg agcctatttt tgtgtagaaa aaaagtccca
     7021 tatgacctat aatgaaaagc gacaaaacaa ctcattagaa agaatcatat ggaacaatta
     7081 cattttatca caaaattact agacattaaa gaccctaata tccagatttt agacatcatc
     7141 aataaggata cacacaagga aatcatcgcc aaactggact atgaagctcc atcttgtcct
     7201 gagtgcggaa gtcaaatgaa gaaatatgac tttcaaaaac cttctaaaat tccttatctt
     7261 gaaacgactg gtatgcctac tagaattctc cttagaaagc gtcatttcaa gtgctatcac
     7321 tgttctaaaa tgatggtcgc tgagacttct atcgtcaaga agaatcatca aattccttgt
     7381 atcatcaacc aaaagattga tcagaagcta attgaaaaga cttctatgac cgacattgat
     7441 catcagttgt ctatttcaac ttcaactgtc attcgcaaga tcaatgattt tcactttgag
     7501 catgattttt cgcgtcttcc tgagattatg tcctaggacg ttgaaacagt ctggggagtg
     7561 actgtttcaa tcgggagata gagatgagct ttattgctca ggactttgat aagctcaata
     7621 tcataactgt tcttgagagc agaacacaag ccatcatccg aaatcccatg aatacaaggc
     7681 tatcaagcga tactgaaagc tcattcaaca agatagtcag aaactgagtg ataaacgatt
     7741 ttatcgccct acttttcgta tgcacttgac taataaagaa attctagata aacttttgag
     7801 ctattccgaa gacttgaaac accactataa tctctatcag ctcttgcttt tccacctctt
     7861 tttcagactc tgtttaaaac cttcctcaaa gataaagaga aaatcgtcaa cgcccttcaa
     7921 ttaccttatt ccaacgccaa actggaagcc accaataatc tcatcaaact tatcaagcac
     7981 aatgcctttg gttttcgaaa ctttgaaaac ttcaaaaaac ggatttttat cgctctgaac
     8041 atcaaaaaag aaaggacaaa atttgtcctt tctcgagctt agcttttctt caacccacta
     8101 cagttgacaa agagccagaa aacgcataat agcaggtgtc aagacactta atattatgcg
     8161 ttttctcatg aaaaaattct cttttcatac tcatttaaaa tcaaaaaggg aatttatcgt
     8221 tttacggaca tgtatattac agatttctat aggtcgtgta tagacaggat atcatcgctt
     8281 ggaagttttc ctttttgaca ccaatcagta atttagttct caggaattaa tggcagtgct
     8341 tttcgtacat agtttcataa ctacagtata gcatagtata tcgctttata gttttcacta
     8401 ttgatgaact gcttgagctg ctgtgatgag ggtcaacttg taaacatcat ctgcattaca
     8461 tccacgagaa agatcattaa ctggcttgtt taaaccttgc aaaacaggtc ctacagccgc
     8521 aaagccaccc aggcgttcag ccatcttgta accgatattt cctgcctcga tacctgggaa
     8581 gatgaagaca tttgcttgac cagctaccgt acttccagga gctttcagag ctgcagtttc
     8641 aggaacaaag gctgcatcaa attgcaactc accatcgatt tcaaggtcag gacgcaagtc
     8701 gtgagcaatt ttagttgctt caacgacctt atcaacgctt tcaccaaacc ctgagccttt
     8761 agtagaatag ctcaacatgg caattttagg ttcgatgcca aacatcttag ctgtgattgc
     8821 tgagttgatg gcaatttcag ccaaggcttc tgcatctgga ttgatgttaa tggcacagtc
     8881 tccaaatagg taacgttccg taccacgaac catgaggaag gctcctgaag tacgagttac
     8941 atttggacga gttttgatga tttgtagagc tggacgaact gttgaagctg ttgagtgaat
     9001 cgctcctgac accattccat caaccaagcc caagtaaacc aacatcacac caaagtagtt
     9061 gacatcttca accaaaacct tgcgtacatc ttcttcagtc attttgccct tgcgacgctc
     9121 caccaaggca gaaaccattt cttcaaattg aggataatgt tgagggtcga tgacctcata
     9181 accatccatg attccttcaa tttcaagata aattttaatt ttttcaggat ttccaagcaa
     9241 aacaggaatc acttctgttt cttttactaa gcgttttgtt gcttgaagaa tacgaggctc
     9301 ttccccttca gggagaacga tacgagcatt tttaccaaca aggttggctt tgagactttc
     9361 aaaaacttcc atgagttttc tcctttaaga taataattat actctgagac agtttttata
     9421 gagtattagt tgataactgg gtaataaggt tactgaaatc atccggcaag ggactttcta
     9481 actgcaagtc ttgctctaaa aatggatgat aaaaggatag gtaatggcaa tgcagagcct
     9541 gacgttgaat accatcttcc agactaccac catacaaatc atctcccagc aaaggaaaac
     9601 cgatatgaga aaaatggact cggatttgat gggttcgacc agtgtgcagg tgaatataga
     9661 ccaagtgaat atttccataa gaagctacaa tcttgtatga agtatgggca tactttccgc
     9721 ctttagccac tcgtctggta ataatggaat cttcatcacg cgcaatcgga gcaataattt
     9781 ccccttctgg ctccaaatgt ccatctccct taaccaaagc aaagtagcgt ttctcgatag
     9841 atttcttctg caactgcttg tctaatcgtg catgggcata accgtgcttg gcaaagagca
     9901 tcaagccaga agtgtcccta tctagtctgg taacaatgtg aacctgctga ttttcataat
     9961 tttgcttgac atagtaaccc ttgataaaat tggcaatggt attagagtga ttgacactag
    10021 gaatagaagc cactccatag ggtttattca agactagaaa gtggtcatcc tcatagagaa
    10081 tatctaatgg atgctcaata gcctccaagg tttcaaagcc ttcctcagcg ggaatgtaaa
    10141 tggtaacgta gtctccaacg tccaatagat acgttgcatt ttgcggttga ttattgacca
    10201 gaatagctcc acctcgaaac ttaatcttag ccagcaatcc cttagaaacc tcgtgctttt
    10261 ttaaaaaggt cttaaccttg acatgttcat ctgcgataaa ttcaaacctc attcatccac
    10321 ctcaccgata aaggcatcct taacacggtt ccagaaactg gtatggctag gagtcgcgac
    10381 aaagtgaatc ttatgatggt cgatttgata ctcaatacgc tcaatattac ggaaagaata
    10441 aacgctattg tcaaccgaaa tagtatgata atcgtttctt gttggaataa gttcaatctt
    10501 atccttctta ggcacaataa tggaagagcc cagtgttcga taaacacgat tattaaggct
    10561 ggcaatttcc gttaattgca aagcttcaat ggtagggtgt aaaacagcac cgccaagaga
    10621 cttgttatag gcagtactac cagtcggtgt cgaaactgtt agcccgtctc cacgaaaacg
    10681 ttcaaaggga acaccattta ttacaatatc tgccaccatg gttcgatcag acctgcggat
    10741 gctggcttcg ttgagtgctc tgaaaatctt aacttcacca ttttcaagaa agaccttcac
    10801 attcagaaca gggtaagaaa cccttgcccc agtatctagc tgcaaattag tcactagctt
    10861 gtccaactca aaatcacgat aatctgtata gaagcccaaa tgtccagtat gaagaccgat
    10921 aaagcggacc ttgtcaagct gattttcgta cttatgaaag gccgacaaga gcataccatc
    10981 cccgccaatg gaaatgacaa tatccggatt ggtatcattg agtataaact gatttctctt
    11041 caaacgatct cgcaattcat acaaaaccct ttgactctgc ggttttctat tggctatcag
    11101 atcaattcgt ttacctgtat tcttcatctg tatcgtcact gtttcctaca ccgtcattta
    11161 attttctact caaaggatca aaaagtgcct gggcttcttg gatatcatca cgaatttcac
    11221 ccatttcttc atccaactga tgggcgattc tagctgtaat ttccagtcgc ttcttaatct
    11281 catctgggaa atccccttgg tacttgtagt tgagagaatg ttctatcgtt gcccagaaat
    11341 tcatggccaa agtacgaatt tgaatttctg ccaaaatagt cttagctcca ttgatggtat
    11401 caaccgtata ttctactacc acatgatagg aacgatagcc tgatgctttt ctatgagtaa
    11461 tgtaatctcg ctcctgtatg attcgcatat cctgacgctt gtgcaaaata tccactactt
    11521 ccttgacgtc atctacaaac tgaaccatca cacgtaagcc agcaatatcc tgcaaatcgt
    11581 gttccaaggt cgcataagta atgccacgac gagccatttt ttctttgatg ctctcaattg
    11641 gcttgactcg accggtcaca aactcaattg gagaatgctt attttgctta cgatattgct
    11701 tacgaatacc acgaagttta atctttaact caccaacagc ttgaatgtaa ggatctagaa
    11761 attcttccca ttctaaggtc atatattctc ccttgttctc atattatccg tcaaaaatat
    11821 ctttgatttt ttctccagat tcatatacaa taaatacaat gcttattata ccataaatcc
    11881 gctttcaacg ataaaaaaag gtaagaaaaa tgaaacattt agaaattgaa ttgaaaacac
    11941 tattgaaaaa agatgaatac aatcgtctaa aagaccagtt cacaggtgtc actcctgttc
    12001 ttcaaacaaa ttactacata gacacgcctg attttgaact gcgagaaaag aaagtcgcta
    12061 tgcgcattcg aacctttgaa gactgggctg agttgacact caaagtcccg cagagtgttg
    12121 gaaacatgga atacaaccaa aaattgcaac taaaagatgc tgagaactat ctgagtaagg
    12181 aagaacttcc tcaaggacta gtactggatg aattggcgaa acatggtatc caaagtaaga
    12241 actggcaggt tcttggttgt ctaacaacgc ttcgctatga aatgaaaaca gctattggtc
    12301 tcatggcact ggatcagagc cgatactttg atatgacaga ttacgaattg gagcttgaag
    12361 tggaaaatca tgagcaaggc aaacaggatt tccgacaatt tttagagaaa aatcagattt
    12421 cctaccaaaa agctccttca aaattggttc gatttgtcaa aagtatgaaa aatagctgaa
    12481 ataatctcca ttttttggta aaatagaaaa gataaaaata cacaaaccct agttcatata
    12541 tgtaaggtaa atataactag gatttataaa gtttacagag gacggtctat aatgtcagat
    12601 agaaaaaaca tgaaactttt cgcacttaac tctaaccaag agattgcaca gaaaattgcc
    12661 caagctgttg gtgtcccact tggaaaacta tcatcacgtc aattttcaga cggagaaatc
    12721 caagtaaata tcgaagaaag tgtccgtggt tatgatgttt acatcatcca atcaacaagt
    12781 ttccctgtca acaaccacct aatggaactg ttaatcatgg tcgatgcttg tgtgcgtgca
    12841 agtgcccaca gtatcaacgt tgtccttcca tattttggct atgcacgtca agaccgcatt
    12901 gcttgtcctc gtgagccact tacagcaaaa ctagttgcaa atatgctggt taaggctgga
    12961 gttgatcgta tcctgactct tgatttacat gccgttcagg ttcaaggttt ttttgatatt
    13021 ccagtggata atcttttcac tgttccccta ttcgcaaaac attactgcga taaaggattg
    13081 cttggttcag atgttgttgt cgttagccct aaaaattcag gtgtcaaacg tgcgcgtagc
    13141 ctggctgaat atcttgatgc tcctatcgcc attatcgact accctcaaga cgatgcaact
    13201 cgtaacgaag gttatattat tggtgatgtt gaaggtaaga aagctatctt gattgatgat
    13261 attttaaata caggacgtac cttctctgaa gcttctaaaa tcgttgaacg tgaaggagct
    13321 acagaaattt atgctgtttc tagccacggt ctcttcgtcg agggagctgc tgagcttctt
    13381 gacaatacta atattaaaga aattcttgtg actgattcag tagcaacaaa agaaaaaact
    13441 cctaaaaatg tatgctacat cactgctagt gagttaattg gtgatgctat cgtccgtatt
    13501 cacgaaagaa aaccagtcag cccactcttt gcctacaata aaaagaaata aggtgattct
    13561 ttgatttatt tggacaatgc tgcaacgact cctatgtcag cagttgctat ttcagctatg
    13621 accaaggtta tgcaagaaac ccacggaaat ccttctagta ttcatggtca tggtcgtcaa
    13681 gctggcaaac tcttgcgaga agcccgtcag gaactagccc agttactaag gacaaaacct
    13741 caacatatct ttttcacttc tggtgggact gaaggcaata atactaccat cattggctac
    13801 tgtcttcgtc accaagaaca aggaaaacat atcatcacaa ctgccatcga gcaccatgct
    13861 gtccttgaaa caattgatta cttggttcaa cactttgggt ttgaagcaac cattatccag
    13921 ccagaaaatc aagaaatcac agcccagcaa attcaaaagg ctttacgtga cgatacgatt
    13981 ttggtttcta ctatgtttgc caataatgag acaggaaacc tacttcccat cgctgaaatt
    14041 ggccaaatac tcaagcaaca ccctgctgcc tatcatgttg atgcagttca ggctattggt
    14101 aaaatcccaa ttcattcaga agaattgggc attgattttc tcactgcttc tgcccacaaa
    14161 ttccatggtc ctaagggaat cggttttctc tacgcatcta gcatggactt tgattcctat
    14221 ctacatggcg gagatcagga acagaaaaaa cgtgcaggaa ctgaaaatct gcctgccatc
    14281 gtaggcatgg ttgcagccct aaaagaagac ctagaaaaac aagaagaaca ttttcaacat
    14341 gtacaaaatc tagaaactgc ctttctggca gagctggagg gcattcagta ttacttgaat
    14401 agaggaaaac atcatctccc ttatgttctc aatattggat ttcctggtca gaaaaatgac
    14461 ctcttactcc ttcggctaga tttagctgga atttcaatct ctactggctc agcctgtact
    14521 gcaggcgttg tccaatccag ccatgttctt aaagccatgt atggcgcaaa ttcagaacgc
    14581 ttgaaggaat cccttcgcat cagtttgtcg ccacaaaata ccgttgaaga cctacaaacc
    14641 ctcgcaaaaa ccttaaaaga aattatcgga ggttagccat atggcatttg aaaaaatcat
    14701 tcagttaaaa aattgtcgtt acgattacac tcttagccct tctgttaaaa aattcaccct
    14761 caaagataac accttttttg aaactaaggt tggtaactat gaactgactc gccttttgga
    14821 aaaagtgcca aacagcggtg aaggcttcca actcaaaatc atcattaaca aggaacttac
    14881 aggggctaaa atcaatatca ctgacaagtt tggccttcgt ctagttgata ttttcaaatc
    14941 agaagaccac catattcatc aggaaaaatt ctacttcctc atggatagct tggtagaacg
    15001 tggtgtcttt acaaaatcgg aaagatagag ccaaaatgtt tgaactgacc tataaggact
    15061 gctatcatgt agagcgtact ctcaagtatg aggatcatga ggctctcatg ttgactttgt
    15121 caggatgtgt aaccttacca gatacacttt atgtgacttc tctgactttt aggggcaaaa
    15181 aagtttatca ggggctggtc ggagacctct accgttttct atctcatgca gattttttac
    15241 atcaaaacta agatttttct tagttttttc ttatttttgt tgattttttc acaatgtttc
    15301 tataaaatag aagaatagaa aggttgtgat tttgtgaaag ataaacagtt tgctattcca
    15361 aaagctacag caaaaagact ctctctctac tatcgaattt ttaagagatt tcatgcagaa
    15421 aagattgaac gtgccaactc taagcaaatt gcagaggcta tcggtattga ttcagcgacc
    15481 gtacgtcgtg atttttccta ttttggtgaa cttggtcgtc gtggttttgg ctatgatgtc
    15541 aaaaaactaa tgacattttt tgccgatttg ctcaatgaca actctattac caatgtcatg
    15601 ctggttggta ttggaaatat gggccatgcc cttctccact accgcttcca cgaacgtaac
    15661 aagatgaaga ttatcatggc ctttgaccta gacgaccatc ctgaagtcgg tacccaaact
    15721 cctgacggga ttcccattta cgggatttct cagatcaagg ataaaatcaa ggatgctgat
    15781 gtgaagactg ctatcctaac tgttcccagc gtcaagtcac aagaggttgc taatctcttg
    15841 gttgatgctg gtgtgaaagg aattctcagt ttttcaccag tccatctgca tttaccaaaa
    15901 gacgtggtcg ttcagtatgt cgatttgaca agtgaactcc aaaccctcct ctacttcatg
    15961 cgaaaagagg attagaaagc gaaaatcatt ttatgaaaaa accagttatt gggattacag
    16021 gaaacgaaaa aactcatcca gatgatgaca tcatgatgag ctacgcagca aaaggctttg
    16081 ttgaaggcgt taaagatgct ggagggattc ccatcatcct accgattggt gatcaagaaa
    16141 tggcctgcca ctatatcagt ttgattgaca agctcatctt gacaggtggg caaaatgtcg
    16201 atccaaaatt ttatggcgaa cccaaaacca ttgatagtga tgactatcac cttcaaagag
    16261 atatcttcga actggccctc atcaaggaag ctattaaaca gaaaaagccc attttctctg
    16321 tctgccgtgg tacccaactc tttaacgttg ccatgggtgg aactttgtac caagatatcg
    16381 aagaccattg gcaggattct tctgttgagt acacaactca acgcttggta acagaaccag
    16441 ataccgttct ccaagaaatc tatggagaaa tctctcatat caactccttc caccaccaga
    16501 gcatcaagga cttagcacca aatttaaaag ttgtggctca tgatcctaaa gatggtatca
    16561 ttgaggctgt catgagtacg gatgatgtcg cctttctcgg tgtccaatgg catccagaac
    16621 ttctttttga aaatcgtccc aaagataaaa aactctttga ctatgtcgtt aatgaacttt
    16681 agattaaatc tgtcttttca cgataactaa agtaattaga atgagagaca atcaaatggt
    16741 ccaagagaac aatccccatc aattcgcagg cttctttaac aagtttagtg acatgatcat
    16801 cattttggct aggcgctacc gctcctgaag gatgattgtg gaccaagata agagaagtcg
    16861 ccatatgctt gattgcatag tgaagaatct ctcgcggttc agcgatacta cgagttacag
    16921 acccgataaa aatggtctgc tgatggatga tttgattttg agtattgaga tagagtgcca
    16981 ccaggtgctc ttgtttttta tcccctaatt cctgctgcat cttcttggcc aacttttgac
    17041 tgctgagaat actttccatt tcaagagtct cgtgtttgtg aatacgatgc cccagttcaa
    17101 tcatagcttg taattctatg gccttaacac gcccaatacc agacaaactc tgcaattcct
    17161 gcagggtcat ttttttcaaa tccgttaggc ttgaaagatt gttcaagact ttttgggcaa
    17221 tttcaaaaac gctagcttga cgtgttcctg tcctgagtaa aatagctagc aactcttggt
    17281 tactaagcgc ttcaactcct tccttggcca gcctttctct tggtaatagt gaatcttctt
    17341 ggaatgaaat actgtacata aaaatcctcc tcactttatt attcgtgaga aggatggaaa
    17401 attagatttt tttctcaatt ggagccacac tggctaaaag ttttttcaaa cctacttctg
    17461 ggaaattgat tttcaattcc tgcctagcac cgctacctga aacttccaga acggttccct
    17521 ctccccattt cttgtggaga gcaatatcac caatggacca atttgcctcg ctagatgctg
    17581 gttttgcgcc agctgtaaat tgaccaaatg gaagaccgct tgactggatt gattttgggg
    17641 cagcaccgcg tttacggtct tgaagagcct gagccaaact cataccttga ccaaaggaaa
    17701 tactaccact gctatatgat gccttaaagc ttgtatttgc aggacgagcc agaccttgat
    17761 actcaagcaa gtctgaactg atttcgttaa taaaacgagt cggacggtta taattggtac
    17821 gaccaaaaag caagcgtgag ttggcattgg tcagatagag aattttctct gcacgcgtga
    17881 tacctacata ggctagacgg cgctcttctt ctaattcatc tgaatcttca gtcgcacgac
    17941 taagtggaaa gacattttct tccatcccaa tcaaaaagac aactggaaat tcgagacctt
    18001 tggcagcatg cagggtcatc aaggtcactt ctgatgtctc ctgactacct gaatctgtgt
    18061 cggcaatcaa agccaagtca tttaagaaac gactcagttt gtccagacca gtttcctctt
    18121 ctgtcacatc cgtggtgtca tcaaagttct tcgtaacaga aagaaactct tcgatatttt
    18181 caacccgtgc cttgctttct agagtcgctt gggcgttaag aatatcgaca taacctgttt
    18241 tttctaggac ggactcaacc aactctgtaa tgcttaagtg gtctagctgc tcccgcaaat
    18301 caagcatcat attggcaaaa tcccagatag attgggctgc cttacccttg ataccagaca
    18361 acataatatt agcagaagca tccagcatag acatattttg caaatttgca aaatcacgga
    18421 ttttctcaac tgtacctaga ccaattccac gtttaggctc gttgataata cgctcaaaac
    18481 taatattgtc actcaaatta gcaataaggt tgagataagc aataatatcg cgaatttcct
    18541 tacggctgta gaatttggtt ccgccaacca tggtataagg aatgttagac ttgagcaggg
    18601 cttcctcaat tgtacgggac tgggcattag tccgatagag aactgcaaaa tccttatgaa
    18661 ggaagttttg actgcgacta agttcatcga tggttctggc tacaaataca gcctcatcca
    18721 gctcatcatc ggcacgatag taaacgattt gctccccatc agcgttttga gtccagagat
    18781 ttttaggacg gcgattttta ttatttttaa taacctcgtt ggccgcttgg agaatggttt
    18841 tggttgagcg gtaattttcc tccaacaaaa caaccttggc tttggggtaa tccttttcaa
    18901 agtccaagat attctgcata tcagcaccac gccaaccgta gatagactgg tccgcatccc
    18961 caaccacaca gatattttta aaacgggaag ccaagagttt gaccaattgg tactgagcgt
    19021 ggttggtatc ttggtactca tcaacgtgga tgtattggaa tttttgctgg tagtaggtca
    19081 aaacatcagg attttgatca aagagacgca aggtcagcat aatcaaatca tcaaagtcaa
    19141 cggattcaga ctgacgaagt tctttttgat aggctgtata acactgggcc acaatttgcg
    19201 tatacatatc gccagcttgg gcagcataag caacatcatc aatcaaatca ttcttagcat
    19261 tggaaatggt ccccaaaata gttcgttcat tccatttttt agggtccaag ttcaactgtt
    19321 tgagaatacg tttcatgagc gttcgctgtt caccaggatc cacaattgta aaattacgat
    19381 tgtagccaat atggtccgca tcgcgacgca aaatacgcac acacatggag tggaaggtcg
    19441 caatcagaca gtcctgagtc gctggattga ggctataagc acgctctttc atctcacgcg
    19501 cagccttgtt ggtaaaggta atggccaaga tattccaagg attgaccagc ttttcatcaa
    19561 tcaaataagc gatacggtgg gtcaaaacac gagtctttcc agaaccagcc cctgccatga
    19621 ttagcaaggg accttctgtc gtttgcaccg cctcagcctg acggtcattc attccattta
    19681 ataatgcgtt catcttctct tccttactct tgaagtcaat atttctatta tatcagaaat
    19741 cagggaaaat agaaacttta cggggagtag caaaatatag tggattgaaa ctagaatact
    19801 acactgtggg tttctaaaac actcgacttt tcacccaatt ttttcataaa ctagctcaat
    19861 acctcaatag acttcctgca aaactagaat cctagttcat gattgataat accagcactc
    19921 aaattcattc gtaatccgaa gcgtttacga tgatttcgat aggttgttga aaatatttta
    19981 aacgttttta ctttggcaaa gatgttctca accttgcttc tctccttaga tagcgcatgg
    20041 ttataggttt tatcttcaac tgttagcgac ttgaatttgc tggatttacg tggagtttgt
    20101 gcttgaggat atatcttcat gagcccttga taaccactgt cagccaagat tttaccagct
    20161 tgtccgatat ttctgcgact cattttgaac aacttcatat catgacaata gttcacagtg
    20221 atatccaaag aaacaattct cccttgactt gtgacaatcg cttgagcctt catagcgtga
    20281 aatttctttt taccagaata attcgctaat tgttttttta gggcgattga tttgtacttc
    20341 cgtcgcatca atcattaccg tggcctcaga actgagagga gttcttgaaa tcgtaacacc
    20401 actttgaaca agagttactt caacccattg gctccgacgg agtaagttgc tttcgtgaat
    20461 accaaaatca gccgcaattt cttcataagt gcggtattct cgcacatatt gaagagtggc
    20521 cataagaagg tcttctaggc ttaatttagg ttttcgtcca ccttttgcgt gtttaagttg
    20581 ataagctgtt tttaatacag ctaacatctc ttcaaaagtg gtacgctgaa caccaacaag
    20641 acgcttaaat cgtgtatcag ttaattgttt acttgcttca tcattcatag aactactata
    20701 ccatattttg tttcgcagga agtctaatct aaaaaaggta aatttaagat tggcaatacg
    20761 aacgttaaac agaattccat ttctcttttt agaatcaaaa cgacaatatt gtggaatctc
    20821 tacaggaaca ataaactgcg acactaaaat atcctccctt agttttactt tactaatagt
    20881 atataggagg agagccctga atcctagacc ctttgttatg atgcgcttac aaacagagtt
    20941 ggaaaaaatc ttaaaagcag aaaaacgcat gatatcagcc cctaacactt gatacaatgc
    21001 gttttattat gaaaagatct actggatttt ttatcaaaat aaacttccag tagtcttttc
    21061 actttttatt aataagttcc ttcttcacct tggctagtca agataacagg tccatctttc
    21121 gtaatgacaa attggtgttc atactgacat gacaatccac cgtcaatggt cttatgcgcc
    21181 caaccagttt tcatatctgt atcaatttcc caatcgcctg tattgatcat tggttcaatg
    21241 gttaagacca ttccttcacg aagacggagt ccacgacctg caataccata gttaggaacc
    21301 attggttctt cgtgcatagt tgggccaaca ccatgaccaa ccaaatcacg cactacaccg
    21361 taaccacgac tttcagcgta ttcttgaata gccgcaccga tatcaccgat acgatttcca
    21421 acaacagctt gctcaatacc cttgtacata gcttctttgg ttacatccat caagtttttg
    21481 acttcttcgg acggtgtacc aacagcataa gcccaacatg agtctgctaa accaccagaa
    21541 tagctctgag tgtatttttt catttgttca acattgttga agtttaattt tgagacattc
    21601 aggtcagatt tagcaatggg acctcccaaa accatatcaa ctttgagcaa atcaccatct
    21661 ttcaagatat aatgacgagg gaaagcgtga gccacttcat cgttaagaga gcaacaggta
    21721 gcataaggat agtccatcat ggcaccgtca accccaatct gaagtggaag gaaattttct
    21781 tctttacaac gacggcggac atattcttca acttcccaca tatctacgcc tggtttaatc
    21841 aaatcacgta agcctatatg aatacttgct agaaaatcac cagccttgtc catagcttcg
    21901 atttcacgag ctgattttaa tgttatcatc ttttctccta gtttctaatt aattttaaca
    21961 gtcacatttg cttttgaaac aatctggtga ccatgataaa tatcgtaatc aattatagct
    22021 gaccgtctcg tatgatgaat aatccgtgcc tgaatgcgca atatatcatc tatctgaaca
    22081 gcctgcaaaa agtagatcag catctgctcg ataatgagat tgcgaccact attaacaact
    22141 aaatcttggg tcatgtgggt cagaatttct gccaatacac cattagccaa aactccattt
    22201 ttttctagca taaagggttc cactgtaatg actacttcat catggtgata agagagcttt
    22261 tgtccaatct gctcagaaaa agttggtaga gccgaaactt gggaacggct catcttctcc
    22321 atgacatctc gtcgcgtcac aacgccaagc aaagtttgat tgcttcgaac aactggtacc
    22381 atttcaaagt cttctgcgat catccgttga ctcacattgg caatatttgt cgataatcca
    22441 accaaaaata gactacgaga cataacctta tcaattgtcg tgcttggtga tttatcacca
    22501 gcgtctctca tggttacaac gccaacaacg acctgatgtt gattgataac agggaaacgg
    22561 ctgctacgat tcttacgaac caagtccaaa taatctttaa ctgtatctgt ctctctcaga
    22621 aaaccatact catgactagg gcgataaagt ttctcaactg tcagaatatc agtcttgatt
    22681 tggacatttg acaaggcttt attgatcatg gtcgcgacgg taaaggtatc atgcttactt
    22741 cttagaacag gaatcccttt ttgattggcc agtttaagca catcatcatg aacctgaaat
    22801 ccccctgtaa ccagaactgc attttcattt tccaaggcta gcaactgaat acgggttcgg
    22861 tctccgacaa tcaagagccc cccatcatga aggtaagaca agatattttg ttcagtcatg
    22921 gcaccaattg aaaacttact aaactctctc tctaaacctt cttgcccagc cagaacctca
    22981 gaagaggtca cttctgcaat ttcagcaaac gttaatctct ctatagcaac tttctgggat
    23041 ttaacacgaa ttgttccact tctaggacgg gtctccacaa ttccacggtt ttcagcttct
    23101 ttaatagctc gataggctgt tccatcacta actcctagat gattcgaaat gctacgaaca
    23161 ctgacccttt tacctactgg taattcctcc aaatagctta gaatttcctg atgcttactc
    23221 attgaactct ccttttacat accgaaattc aagataatcc cgcatttttc ttgtgtaacg
    23281 atcacttccc ttaaactgac ggaacaaact aaatccagac ttaagagcaa ctctttggct
    23341 agcttcattt tcaaggtggg taatgataga taattgtttt aagccaaatt cctcaaaaga
    23401 aagctgacaa atttttctaa caacctctgt cataaatcct tgcgaccaag catcttttct
    23461 caaaaaatag ccaagctcag cttctttttt gatttcatct aacttctcaa atttaataga
    23521 accaatcatt tgttgatttt tctggtcaca aattgcccac actcccaaag gggacttcat
    23581 aaagtaattg gccagtgcat attgactttc ttccagactt gcctgcgttg ggaaaataaa
    23641 ttgaagattt tctggatttg aagctatctc gcggaagtcc tgactatcac taaaaaagaa
    23701 aggacgcaaa tacaagcgat ccgtttcaaa aaaagaaaac attgctaatt tggtccaaat
    23761 attcataaac acctctacgg tttaatcctc aacaagtcta atatccgctc ctaaattacg
    23821 taatttttcg ataatatcag aataaccacg taagataaac tcgatattgg taatttcagt
    23881 tttaccttca gccataagcc cagcaatgac tagtgcagcc ccagctctta agtcggtcgc
    23941 tttaacactg gccccacgta aatcacgtcc acccgtgtac aaaatatgac catttgttgt
    24001 cgaaatatcc gcatccatct ttgctagttc aaaaacatga tttacacgtt tttcgtaaat
    24061 cgtatcgaca attgtaccac gaccattcgc tcttagtaaa agaggggtaa gcggttgttg
    24121 caaatcagtt gcaaagcctg ggtaaggagc tgtcttaata ttgattgctt tcaaattaga
    24181 ctgttcctcg acaaaaatgc tgtcttcaga tacagtcatt ctcactccca tttcttccaa
    24241 cttagcaata aacccttcca ggtgttcgta aagaacatta tttatacgaa ttcctttacc
    24301 aactgcagca gctaaagata tatatgttcc agcttcaatg cggtctggaa tcacctgatg
    24361 acgtgtccca tgtaatcttt caacaccatc aataatgatg atattagttc ctgccccacg
    24421 gatatgggcg cccatattat tcaagagagt agctacatca ataatctcag gttcacgggc
    24481 tgcattttca ataatagtac gaccatttgc tttaaccgca gcaatcatcg tattaatcgt
    24541 tgctcccaca ctaaccgtat ccatgtaaat acttgcacca tgaagtcctg tatctttagc
    24601 agataacttc atgttatctc cctcgtagct agcagtggca cccatagctt caaacgcctt
    24661 aaggtgtaag tcaatcggac gaggaccaag atcacatcct cccggtagac caactgtcgc
    24721 ttcaccaaaa cggcctaaga ggctcccata aaaatagtaa gatgcacgaa gactgttaat
    24781 tttaccataa ggcattggaa tattttgaac acctcttggg tcaatctcca atacatcgtc
    24841 ataacgctta acagtagctc ccatcaattc catgatttcg acaagactgg ctacatccga
    24901 aatatctgga acgcaatcca aagtcaccac atcatcagcc aagataatag ctggaattaa
    24961 ggcaacgaca ctatttttag caccactaat agtgatttca ccttgcagtg gtaatccacc
    25021 attgataaca atttttctca ttctaagttt tcaatactct ttcaagattt ctaataaggt
    25081 cttcaaaata aagtatatca taaatttatc cttttttcca tccttttcaa ttttattgga
    25141 taaatcagag ttgacgagtt agtaactgaa ttactaatac tcaatgaaaa tcaaagatca
    25201 aactaggaaa ctagccgcag gttgctcaaa acactgtttt gaggttgtag atggaactga
    25261 cgtagtcagt atcctacaca tacgacaagg cgatattgac gtgatttgaa gagattttcg
    25321 aagagtataa tctttctcga atcgctattg cccctttttt atcccctaaa actgagtagg
    25381 agctaagact agatctctta tctaagtatc ggaatacggc tgttcaacta aattttagca
    25441 agaacttctc ccccttctct cagttcacag aagcgtttta tacataccgt cctatcagac
    25501 agataaccgt gactcaggat cacttctatc tgtcgttttc tctttatagt gatagacctc
    25561 acgggataag tcgtacatct ttcctcgtgt atacaagata taagggcgtt aaaaggttac
    25621 agtgaaaata gaaaatctta gtacgaattc aattactctc gtgatttacg catataggtt
    25681 acgactacct ttttggactt tagagtttga tgccctctta tccgctatat acgccttatt
    25741 atcacgttcc tgttcgtaga gccacgattt cgctatccct tcttctgaca attcttattt
    25801 ccagcgtcag acttaaaacg gtctatcccc agaccatttt aatccgctac ctcacgatag
    25861 tcaggcttgg gaatcgctat ttgactcgcc gagaactttg acatcagata tactataaca
    25921 aattgaaata agaatcaaac aatttaattt tgaaattcaa atcaatttat aacaatatag
    25981 ttgattgaaa ctagaatagt aca
//
LOCUS       DAVKBC010000028        24470 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVKBC010000028 DAVKBC010000000
VERSION     DAVKBC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24470
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.028"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(98..2356)
                     /locus_tag="VWX64_001344"
     CDS             complement(98..2356)
                     /locus_tag="VWX64_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9190809.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPNEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VWX64_001345"
     CDS             complement(2585..2815)
                     /locus_tag="VWX64_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU9190810.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VWX64_001346"
     CDS             3005..3688
                     /locus_tag="VWX64_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9190811.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQCS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEADYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VWX64_001347"
     CDS             3688..4422
                     /locus_tag="VWX64_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9190812.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VWX64_001348"
     CDS             4576..5433
                     /locus_tag="VWX64_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU9190813.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VWX64_001349"
     CDS             5575..6447
                     /locus_tag="VWX64_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU9190814.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VWX64_001350"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VWX64_001350"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU9190815.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VWX64_001351"
     CDS             7426..8637
                     /locus_tag="VWX64_001351"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU9190816.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VWX64_001352"
     CDS             8639..9181
                     /locus_tag="VWX64_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU9190817.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9197..10006
                     /locus_tag="VWX64_001353"
     CDS             9197..10006
                     /locus_tag="VWX64_001353"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9190818.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRTYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10503..11525
                     /locus_tag="VWX64_001354"
     CDS             10503..11525
                     /locus_tag="VWX64_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEU9190819.1"
                     /translation="MKESENDAPKLETPLREEPRLAPQTLLEASEVLENKREESKVGI
                     TEPAQDSPILAPVEETKEEAVTEKPTNTRSLTAEDLVKISKGELHLENDLIDESFYGE
                     KALDLEGDDYQDGIKNKDGKDYLGYNSHPLLADSDGDGLADGEDDNKKEWYVTDRDSL
                     LFMELAYRDDDYIEKILDHKNLFPSLYLDRQEHKLMHNELAPFWKMKKAYYTDSGLDA
                     FLFETKSDLPYLKDGTVHMLAIRGTRVNDAKDLSADFVLLGGNKLAQADDIRKVVGEL
                     AKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDFYNHVLRKVTTFSAPKVITSRTVW
                     DAKNGF"
     gene            11535..12110
                     /locus_tag="VWX64_001355"
     CDS             11535..12110
                     /locus_tag="VWX64_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU9190820.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            12135..12647
                     /locus_tag="VWX64_001356"
     CDS             12135..12647
                     /locus_tag="VWX64_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU9190821.1"
                     /translation="MSAQITINHKKARYFRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLIIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13301..14011
                     /gene="deoD"
                     /locus_tag="VWX64_001357"
     CDS             13301..14011
                     /gene="deoD"
                     /locus_tag="VWX64_001357"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9190822.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(14034..14558)
                     /locus_tag="VWX64_001358"
     CDS             complement(14034..14558)
                     /locus_tag="VWX64_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU9190823.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14611..14847)
                     /locus_tag="VWX64_001359"
     CDS             complement(14611..14847)
                     /locus_tag="VWX64_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU9190824.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14915..15835)
                     /locus_tag="VWX64_001360"
     CDS             complement(14915..15835)
                     /locus_tag="VWX64_001360"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU9190825.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            16025..16429
                     /locus_tag="VWX64_001361"
     CDS             16025..16429
                     /locus_tag="VWX64_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190826.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFICSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16645..17226
                     /locus_tag="VWX64_001362"
     CDS             16645..17226
                     /locus_tag="VWX64_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9190827.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            17223..18500
                     /locus_tag="VWX64_001363"
     CDS             17223..18500
                     /locus_tag="VWX64_001363"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU9190828.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18518..19180
                     /gene="deoC"
                     /locus_tag="VWX64_001364"
     CDS             18518..19180
                     /gene="deoC"
                     /locus_tag="VWX64_001364"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU9190829.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            19167..19556
                     /locus_tag="VWX64_001365"
     CDS             19167..19556
                     /locus_tag="VWX64_001365"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9190830.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19647..20699
                     /locus_tag="VWX64_001366"
     CDS             19647..20699
                     /locus_tag="VWX64_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU9190831.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20843..22378
                     /locus_tag="VWX64_001367"
     CDS             20843..22378
                     /locus_tag="VWX64_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190832.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22371..23429
                     /locus_tag="VWX64_001368"
     CDS             22371..23429
                     /locus_tag="VWX64_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190833.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23432..24388
                     /locus_tag="VWX64_001369"
     CDS             23432..24388
                     /locus_tag="VWX64_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190834.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         7127 a         4407 c         5578 g         7358 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgtttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttgaccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt cgtccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa tgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcgga ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcagt caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccac ttttatttgc
     3601 agcattttac tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggcatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag gttatctttg agggagtcga tattacggac
     3901 aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gattgaaaat attaccttgt cacctatcaa gaccaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa ccgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttgttgta taataaaagt gagagggaaa aaggatgaaa
     5581 gtgattaatc aaaccttact agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagtta tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagat
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctgcttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaaaga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa tcatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggagctt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 tagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctggg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca gaagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt gggtcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caaggtcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 taggacctac acaccagaat accgtgccac tgcccatgaa gtagctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccggattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagtggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagtaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttcttag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactggctcc tcaaacgctt ctggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtagg gataacagag ccagctcaag actcacctat tcttgctcct gtagaagaaa
    10681 ctaaagaaga agctgtgaca gaaaaaccaa caaatactcg ttctctaact gcagaagatt
    10741 tggtgaagat ttccaaaggg gaattgcatt tagaaaatga tttgattgat gaatctttct
    10801 atggtgaaaa agctcttgat ttggaagggg atgattacca ggatggcatc aaaaacaaag
    10861 atggtaagga ttatctagga tataacagtc atcccttgct agcagacagt gatggggatg
    10921 gtttggcaga tggggaagat gataataaga aagaatggta tgtcacagac cgtgattctc
    10981 ttctctttat ggagttagct tatcgagacg atgattatat tgagaaaatt ttagatcata
    11041 agaatctttt ccctagtctc tatcttgacc gtcaagaaca caaactcatg cacaatgaat
    11101 tggctccttt ctggaagatg aaaaaagcct actatacaga tagtggcttg gatgctttct
    11161 tatttgagac caagagcgac cttccttatc tcaaagatgg aacggtgcac atgttggcta
    11221 ttcgtggaac gcgagttaat gacgccaagg acttgagtgc agattttgtt ttattaggtg
    11281 gaaataaact agctcaagcg gatgatatcc gcaaggttgt tggggaatta gccaaggata
    11341 taagtattac taagttgtat atgacaggtc attctcttgg aggctaccta gctcagattg
    11401 cagcggttga agattaccaa aaatatcctg atttttataa ccatgtattg aggaaagtga
    11461 caactttcag tgctcctaaa gtcattactt ccagaactgt ttgggatgct aagaatggtt
    11521 tctgagatgt tggtttggaa agtcgtaaat tagctgttag tggaaaaatt aagcattatg
    11581 tggttgataa tgacaatgtt gtgactccct tgattcataa taatcgtgat attgttacat
    11641 ttacaggtaa ttcacgcttt aaacaccgtt ctcgtggcta ttttgaaagt ccaatgaatg
    11701 atattcctaa ctttaatatt ggtaaacaag ctaccttgga taaacatggt tatcgtgatc
    11761 cgaaattgga taaagtgcga ttctttaaga aacaggctct acctcaatct tctagtcaac
    11821 caagcgctga accaatggaa aatattgcct taggaaaaca ggttactcaa agttcgacag
    11881 ctttcggagg agatgctaga agagctgtgg atggcaaagt cgatggtaac tatggtcaca
    11941 attctgtcac tcatacaaac ttccaatcta agccttggtg gcaagtagat ttggctaaag
    12001 aagaaaccat tcgccaaatc aatatttaca accgaacaga cactgcccag gatagattgg
    12061 caaactttga tgtcattctt ttagacagtt ctggtaaaga aattgagtga aaacgtataa
    12121 tatctcctaa agatgtgtca gcacaaatta cgattaacca taaaaaagcg cgctattttc
    12181 ggattgagct agaaggctat aatgccctca gtcttgcaga agttgaagtt ttccgcttta
    12241 tagctacgaa tgctgaaacg gcgacacaag tttctaagcc agttcaacca atcagtcaga
    12301 ctcctgtgaa agataaaaca ttgataattc aacacagtgg agcttacatt gcccgctact
    12361 ccataacttg ggaagaagtt ccagtagata aagatggaaa ccaagttgtt cgtagtcatt
    12421 cttgggaagg aaacggtcgc aaccagactg caggttttgt cctcaacctc ccaatcaaag
    12481 aaaatatgag aaatctgcga gttaagattg agaaaaagac gggcctacta tggaatagat
    12541 ggcaaacaat ctatgaaaac agaccaattt tagctcaacc ccaccgtaaa attacccatt
    12601 ggggtacgac attgaattcc aaggtgagtg acgatgatgt cttgtaatct gatggtagaa
    12661 tgacagttag tttgtctagt ttataagaaa gtactacctg agcttgaata gaactcaggt
    12721 agctctctat gaaagaacaa aattaatact caatgaaaat caaagagcaa actaggaaac
    12781 tagccgcagg ttgctcaaag cactgctttg aggttgtaga taagactgac gaagtcagtc
    12841 acatatataa tccaaggcga cgttgacgtg gtttgaagag attttagaag agtataaaca
    12901 gaaaggtaga gcgcgtgttc taatttgaac acgagtagaa aacttttcta aaagcaaaaa
    12961 cgaaaggatg ggtaaactgt attcgctgaa ctgaatacgg gcgactctcc tctaaatcaa
    13021 aattaagaaa ggaattgacc ccaccctaaa agtagtggga aaaagatagt tggtctagcg
    13081 agcatcgctc actgcgccca actcctattt tcccttcgct ttttgatggg tttggtatct
    13141 ttctcaatat aaaatataaa ataaagaaag atagagcgtg tgttttgatt tgaacacgag
    13201 cggaaaactc ggaaaataga taatctgact gaaaaatcag gatttctcgt caggttccta
    13261 attttcagtc gttttcttct cgctctttgt atcataaatt atgtctatcc atattgctgc
    13321 tcagcagggt gaaattgctg ataaaattct tcttcctggg gatcctcttc gtgctaagtt
    13381 tattgcggag aatttccttg atgatgctgt ttgttttaac gaagtgcgta acatgtttgg
    13441 ttacactggt acttacaagg gtcactgtgt atctgtcatg ggaactggga tgggaatgcc
    13501 atctatttcg atttatgcgc gtgagttaat cgtagactac ggtgtgaaga aattgattcg
    13561 tgtgggaact gcaggttctt tgaatgaaga ggttcatgtt cgtgaattag ttttggcgca
    13621 ggcggctgca accaactcaa acatcgttcg taatgactgg ccacagtacg attttccaca
    13681 aattgctagc tttgatttgc ttgataaagc ttaccatatc gccaaaaaac ttggtatgac
    13741 tactcacgtt gggaacgttt tgtcatctga tgtcttttac tcaaattact ttgaaaagaa
    13801 tatcgagctt ggtaaatggg gagtcaaggc tgtggaaatg gaagcagcag ctctttacta
    13861 tcttgctgcc caataccatg ttgatgcgct agctatcatg accatctctg atagcttggt
    13921 caatccagac gaagacacaa ctgcagaaga acgtcaaaat accttcactg atatgatgaa
    13981 ggttggtttg gaaaccttga ttgcagaata attatagcca aaaaggaagc cctttatgaa
    14041 ttgtaggact tccttttctt atccagaaat tgatctagct ctctctgatt tcgaagaata
    14101 gtgactttat gtgaatattc ttggcaaagt ttttggtaat tttctttttg agttttgcta
    14161 cgcccatccc aaagaatcca tctgataaac tcccactcaa agcgttcagg gcaatctgcc
    14221 gccatacttt ctctgacttt tccacggtat ttaagataac gcttaaaggc tctaaagaga
    14281 caggtcaatg gcgaaaaatt gagaaagatg atttggtcag cttcttgcat tcgttcttgg
    14341 tagtagcacc aagaataatt accatcgatg acccaagctt tatgcttggt gagaaagttt
    14401 tttatctcgg ttaacatcca ttcgcagtca ctgtcttgcc aaccaggttg aaattggagt
    14461 gtgtccatgt gcagttttgg aatggagtag tagttagata acttttctgc tagagttgac
    14521 ttaccagaac cagaatatcc gataattgcg attttcattt tctacctttt cctatttgga
    14581 gacaaaaaaa cagcctctat ggactgtttc ttatttagca agtttagctg aaagacgagc
    14641 tttatcgcgg cttgctttgt ttttgtgaat caaaccttta gtttctgctt tatcgatagc
    14701 tgagctagca gcacggaaaa gttcttcaga tgggtttgct tcgaaagctt ttatagcagt
    14761 acgcatagct gatttttgag ctgagttctt ttcgttttgt ttaacgttca attcagcgcg
    14821 tttgatagct gatttaatgt ttgccaatgt tcttacctcc atatttacta actataccat
    14881 tatatatgaa aacttacgtt ttgacaaggg aaaattactt ttttaagtaa atttcatcga
    14941 tttcatggtt cttgctttta tgaagaatca cttctgcacg atttctggtt ggttcaatat
    15001 aattttgcag atttgtgaga ttgatactgg tccagacctg atgggcaaag gactccactt
    15061 ccccaatcgg catctgagta aaacgataat agtagctatc agggtcgttt tgggctaggc
    15121 tcagcatttt caagaaacgg tccagatacc aactttcaat atcatccact ccagcatcta
    15181 catagatgga aaagtcaaag aagtcagtga tatagagacg atcgttttgt ggattttgaa
    15241 agacattaat tccctcaaca attacaaaat cagcagcttt gacactttgt ttcttttcgg
    15301 gtacgatgtc gtaaacttca tgagaataga caggaatatc tacatcttgt ccatttttga
    15361 tgcggtccaa gaagttgaga agagcttcca tatcatagct ttcaggaaat cctttacgat
    15421 ttaaaatccc ctgctcaatc aaggtttgat tgggatagag aaaaccatca gttgtaacca
    15481 actcaaccgt agcatctgta aacgtacggg acagtaggat ttgaagtagg cgactggttg
    15541 tggattttcc aacggcaaca ctcccagaaa ccccaataat aaaaggttga gatttacttt
    15601 cacgttggag gaaaattcct tttgaaaagg ctaaatcttc cttagttcgc ttgtaaatct
    15661 gaatcagatg agccaagggg agatagatat ctgtaacgtc ttggagactg atttggtcat
    15721 taaaactctt gatagattcc aattcttctt ctgtcaaagg aggtgttgtc tttcgatgta
    15781 aagattgcca agtctggcgg ctgatttttt caaaatgtaa aaattcgttg gtcatttgtt
    15841 ttcccctaga tattttgtct atcataccat aaaaagctaa aaaaataaag cggtttcttg
    15901 aatgtggtaa gtcaatggta tatagtataa gtgatcaatt tattgatgaa ataggagata
    15961 gattctactg atttataagc ttataaaggg ggctttttag ttcacaactt ataggaggtg
    16021 tactatgaaa atcttaaaac gttacatatt ggaactctgt tttattttaa gttttgcttt
    16081 accttttata aaaggagcca atgcagataa tggtagatgc tttgtggaaa cctattacgg
    16141 ttttactttt ttgatggaac atgctattgt aacagctgtc tttatctgtt cgttcttaat
    16201 tgctttctta ctaaaaaaac gatgggcgaa atggattgct gctggtagtt attgcttttt
    16261 agtcctatgg attgcgacag agggttattt cttccgcatg tcactagaag atttgatacg
    16321 actttggaca agtttggaaa tcctgacaca aacgtatcag ttgggctttt atctaaacat
    16381 tttgttagga attttgttga taataaagta ttttaaggtt aagcaataga aataataatc
    16441 tgcctgatta tagatgataa actttttgtt tttatctgga ctgtgatatt tatagttcta
    16501 aatggtttat tatttataag tgttgaaaga gattgaagaa aatggcttcg tgactcgctt
    16561 tcttcggtct ttttcgtttt attatcaatt tgtaaacgat ttacaatttg agtcaaatta
    16621 tggtaaaata gtgtcatgag taaaatgtat tatgcagaaa atcctgacgc tgctcacgac
    16681 attcatgagt tgagagtaga gttgttggga caaaaaatga cctttttaac ggatgcgggt
    16741 gtttttagca agaaaatagt tgactttgga agtcaactat tgctcaagtg tcttgaggtc
    16801 aaccaaggag aaactgtcct tgatgtaggc tgtggttacg gacctttggg tttgtcctta
    16861 gctaaggctt atggagttca ggctactatg gttgatatca acactcgtgc cttggattta
    16921 gctcggagaa atgctgaaaa aaataatgca aaagcgacga ttttccagtc caacatctat
    16981 gaacaagttg aaggacattt tgatcatgtc atttccaatc ctcctatccg tgcgggcaag
    17041 caagtcgttc atgaaatcat tgagaaaagt aaagatttct tggaaactgg tggggatttg
    17101 acaatcgtca tccagaaaaa acaaggggct ccaagtgcta agtccaagat ggaggatgtg
    17161 tttggtaatt gtgaaatcct taaaaaagac aaaggatact atatccttag aagtgtgaaa
    17221 gaatgagagc agttgattta atccaaaaaa aacgagacgg tcaagaactg acttcaagtg
    17281 aaattgaatg gctgatagaa ggctatgtat caggaactgt tcctgattat cagatgtctg
    17341 cctttgctat ggctgtttat tttaaaggaa tgacgactcg agaaatctct gatttaacga
    17401 tgaatatggt taagactggg caagagtttg acctgtcagc cattgatggt gtgaaagttg
    17461 acaagcattc tactggtggt gtcggcgata aggtaacctt gattttagct cctcttgttg
    17521 ctagcttcgg tgtgcctgta gcaaaaatga gtggtcgtgg tcttggccat acaggcggaa
    17581 caattgataa attggagtcc attaggggct atcaagtaga acgtagtcaa gaggatttta
    17641 ttcgtcaggt tcaggatatt ggagtatctg tcattgggca atcagaccag ctggtcaaag
    17701 cagataagct tctctatgcc cttcgtgatg tgaccgcaac tgtcgacacg attcctttga
    17761 ttgcgagttc ggtgatgagc aagaaaatcg cggcaggggc ggatgctatt ttgctagacg
    17821 tgactgtcgg tgagggtgcc ttcatgaaga cggttgatga ggcgcgtgag ttggctcaaa
    17881 ctatggtaga tcttggtaag gttgttggac ggaagacagt agcagtgatt acggatatga
    17941 gccagcctct gggacgagcg attggaaatc gtctggaaat ccttgaagca ttggagattt
    18001 tgcaaggtca aggacgtcag gatattaccc actttatttg tgaattggct caaattatgc
    18061 ttggtttggc aaatgttaac aagactgttg aagaagttcg ccaacatctt gagaatggtc
    18121 aagcactggc taagtttgag gaaatggtgc aagcccaagg tggagacttg gaagacctct
    18181 atcgtcctgt aaatgtagct catgtggtgg aaatccctgc tcaggaaacg ggtgtcattt
    18241 cagctcttcc agctatggac tttggtcttt atgccatgag gttgggtgct ggtcgtgcag
    18301 ttaagtctga tgccttggac tatgaaacag gaattgtttt tgaaaagaag attggagact
    18361 ccgttcaaaa gggtgaaatt gttgcaaaag tatacacaaa tgaaaaaatt ccacctcaac
    18421 tagttacaga tttccaaaaa tgtgttaaaa taagtgatga agtgaaaaaa atccgtgaaa
    18481 ttgtagaaat catctcctaa atggagggaa aaccgaaatg aaattaaata aatatataga
    18541 tcatacgctt ttaaaacaag atgcaaagaa aaaacaaatt gatagtttgt tgtctgaggc
    18601 tagagagtat gactttgcca gtgtttgcgt taatccgacc tgggttgaac atgctaaaaa
    18661 aggacttgaa ggcacagatg ttaaggtttg cacagtagta ggtttccctt tgggagcaac
    18721 aacttcagcc gtgaaagcat ttgagacaaa agaagctatc caaaatggtg cagatgagat
    18781 tgatatggtg atcaatgttg gagctctcaa atcaggtaat ttagccttgg ttgagtcaga
    18841 tattcgcgca gtagtggaag caagtggtga taagttagtg aaagtcatta ttgaagcttg
    18901 ccttctgaca gaccaagaaa aaattgttgt ttgccaattg gcccaaaaag ctggggctga
    18961 ctttgttaaa acatctactg gtttttcaac tggtggtgct acgatagcag atgttacatt
    19021 aatgcgtgaa acagttggat ctgatatggg agtcaaggct gctggtggag ctcgttctta
    19081 tgcagatgct cttgcctttg tcgaagcagg tgcgacccgt atcggaacgt cagctggggt
    19141 agctatttta aaaggagaat tggcagatgg cgactactga gttgattgaa ctggcaattg
    19201 aaaccagcaa acatgcctat gtcccctatt ctcactttcc tatcggagca gttttagtag
    19261 ccaaagacgg aaatgtttac acgggagtga atatcgaaaa tgctagctat cctttgacca
    19321 attgcggtga gagaacagct atttttaagg ctatatctga aggccaaaga gaattttcag
    19381 aattgattgt ctatggtcaa actgaaaaac cgatttcacc atgtggtgct tgtcgccaag
    19441 taatggtcga attttttgaa caagatttaa aagtgacctt agtcgcaaaa gataaatcga
    19501 cggtcgagat gacggtcggg gagttacttc catattcttt tacagactta aattagtctg
    19561 agtcgctctt tgagtggcaa gggtctttgt gaccaatcaa tccatacttg caacatcgtt
    19621 gcacatctta tttaggaggt tcagtaatga acaagaaaca atggctaggt cttggcctag
    19681 ttgcagtggc agcagttgga cttgctgcat gtggtaaccg ctcttctcgt aacgcagctt
    19741 catcttctga tgtgaagaca aaagcagcaa tcgtcactga tactggtggt gttgatgaca
    19801 aatcattcaa ccaatcagct tgggaaggtt tgcaggcttg gggtaaagaa cacaatcttt
    19861 caaaagataa cggtttcact tacttccaat caacaagtga agctgactac gctaacaact
    19921 tgcaacaagc ggctggaagt tacaacctaa tctttggtgt tggttttgcc cttcacaatg
    19981 cagttgaaga agcagctaaa gaacacactg acttgaacta tgtcttgatt gatgatgtga
    20041 ttaaagacca aaagaatgtt gcgagcgtaa ctttcgctga taatgagtca ggttaccttg
    20101 caggtgtggc tgcagcaaaa acaactaaga caaaacaagt tggttttgta ggtggtatcg
    20161 aatctgaagt tatctctcgt tttgaagcag gattcaaggc tggtgttgcg tcagtagacc
    20221 catctatcaa agtccaagtt gactacgctg gttcatttgg tgatgcggct aaaggtaaaa
    20281 caattgcagc cgcacaatac gcagccggtg cagatattgt ttaccaagta gctggtggta
    20341 caggtgcagg tgtctttgca gaggcaaaat ctctcaacga aagccgtcct gaaaatgaaa
    20401 aagtttgggt tatcggtgtt gaccgtgacc aagaagcaga aggtaaatac acttctaaag
    20461 atggcaaaga atcaaacttt gttcttgtat ctactttgaa acaagttggt acaactgtaa
    20521 aagatatttc taacaaggca gaaaaaggag aattccctgg cggtcaagtg atcgtttact
    20581 cattgaagga taaaggggtt gacttggcag taacaaacct ttcagaagaa ggtaaaaaag
    20641 ctgtcgaaga tgcaaaagct aaaatccttg atggaagcgt aaaagttcct gaaaaataat
    20701 ggatggaagt catttcttag gaagcggcca agggccgctt ttttaagagt tgagacaaag
    20761 tcattttgtc tcagtaaagc ttgctactag acaaactagc aagttttatt gaaataaaat
    20821 aagactctga aaggaagagc acatggcaca cgaaaatgtc attgagatgc gtgatattac
    20881 caaggtgttt ggtggatttg ttgctaacga caaaatcaac ttgcacctac gaaaaggtga
    20941 aattcatgca cttttaggag aaaatggggc tggtaagtcc acgctaatga acatgttagc
    21001 agggcttctt gaaccaacta gtggtgaaat cgcggtcaac ggtcaagttg tcaatctcga
    21061 ctccccatct aaagcagcta gcttgggaat cgggatggtt caccagcact ttatgttggt
    21121 tgaagccttc acagtggctg aaaacatcat tttaggtagt gaattgacta aaaatggtgt
    21181 gctagatatc gctggagcta gcaaagaaat caaggctctt tctgaacgtt atggcttagc
    21241 tgttgaccct tctgccaagg tagcagatat ctcagttgga gcccaacaac gtgtagaaat
    21301 tttaaaaaca ctttatcggg gggctgatat ccttatcttt gacgaaccaa cggctgtttt
    21361 gactccatca gaaattgatg agttgatggc tattatgaaa aatcttgtca aagaaggaaa
    21421 atcaattatc ttgattaccc acaaattgga tgaaattcga gcagtttctg accgtgttac
    21481 agttatccgt cgtgggaaat caattgaaac cgttgaaatt gcaggggcta ccaatgctga
    21541 tttggcggaa atgatggtag gacgttctgt ttcctttaaa acagagaagc aagcctctaa
    21601 accaaaagaa gtggttttgt ctatcaaaga tttggtggtc aatgaaaacc gtggtgttcc
    21661 agctgttaaa aatctgtcct tggatgttcg tgctggagag attgttggta ttgcggggat
    21721 tgatggaaat ggtcagtctg aactgattca agccattaca ggtcttcgta aggttgaatc
    21781 tggtagcatt gagctaaaag gagattcaat tgtaggcttg cacccacgtc agattacaga
    21841 actaagtgtt gggcacgttc cagaagaccg tcaccgtgat ggcttgattt tggaaatgat
    21901 gatatctgaa aatattgccc ttcaaaccta ctataaagaa ccacatagta aaaatggaat
    21961 tttgaattat tcaaatatta cttcttatgc taaaaagctg atggaagagt ttgatgttcg
    22021 cgctgccagt gaattagttc ctgcagctgc actctcagga ggaaatcaac aaaaagcaat
    22081 tattgctcgt gaaattgatc gagatcctga tctccttatc gttagccagc caactcgtgg
    22141 gttggatgtc ggtgccattg agtatatcca caaacgcttg attgaagagc gtgataatgg
    22201 caaggctgtc cttgttgtca gctttgaatt ggatgagatt ttaaacgtct cagaccgtat
    22261 tgccgttatc cacgatggta agattcaagg tattgtatca ccagaaacaa ccaataaaca
    22321 agaacttggt gtcttgatgg ctggtggaaa cttgggaaag gagaagagtg atgtctaaaa
    22381 aattacaaca aatttcggtt cccttgattt ctgtatttct aggaatttta ctcggagcca
    22441 ttgtcatgtg gatcttcggt tatgatgcta tttggggcta cgaagaattg ttctatacag
    22501 cctttggcag tctgcgtggg attggagaaa tcttccgtgc tatgggtcct ctggtcttga
    22561 ttggtcttgg ttttgcggtt gccagtcgag ctggtttctt taacgtcgga cttcctggtc
    22621 aggctttggc aggttggatt ctcagtggtt ggtttgcgct gtcgcatcca gatatgcccc
    22681 gtcccttgat gattctagca accatcgtga ttgccttgat tgctggtggg attgtcggag
    22741 cgattccagg tattcttagg gcctatctag ggacgtcaga ggttattgta accatcatga
    22801 tgaactacat tgtcttgtat gtagggaatg cctttatcca tgctttccct aaagacttca
    22861 tgcaaagtac agattcgacc attcgtgttg gggctaatgc aacctatcag acaccttggt
    22921 tggctgagtt gactggtaac tcacggatga atattggtat tttctttgcc atcattgccg
    22981 ttgcagttat ttggttcatg ctcaagaaaa caactcttgg ttttgaaatc cgtgcagttg
    23041 gtcttaatcc acatgcttca gaatatgctg gtatttctgc caagcggact attatcctat
    23101 ctatgattat ttcaggtgcc ttggcaggtc ttggtggagc tgttgaaggt ttgggaacct
    23161 tccagaacgt ctatgttcaa ggttcgtcat tagctatcgg atttaacgga atggcggtta
    23221 gtttgcttgc ggccaactca ccaattggta tactctttgc agccttccta tttggcgttc
    23281 tccaagttgg ggctcctggt atgaatgcgg cgcaggtacc atctgagctt gtcagcattg
    23341 taacagcgtc tattatcttc tttgtcagtg ttcattacct tatcgaacgc tttgtcaaac
    23401 cgaaaaaaca agttaaagga ggtaagtaaa gatgtctatt ataaccttgc tccccctctt
    23461 ggtgtcttct atgctgattt actcagcacc tctcatcttt acaagtatcg gtggtgtttt
    23521 ctctgaacgt ggtggtgtgg taaacgttgg ccttgaagga attatggtta tgggtgcctt
    23581 ttctggagtt gtctttaacc ttgaatttgc agaacaattt ggagcagcaa ctccatggct
    23641 atccttgctt gtagcaggat tggttggtag tgttttctct atcatccacg cagcagcgac
    23701 ggttcatttc cgtgcagacc atgttgtcag cggtacggta ttgaacttga tggcgcctgc
    23761 cttggctgtt ttcttagtta aagttcttta taacaaagga caaaccgaca acctaagtca
    23821 aacttttgga cgctttgatt tcccagtctt ggcaaatatc ccagtgattg gtgatatctt
    23881 cttcaagtca actagtctac ttggttatct ggcgattgcc ttctcattcc ttgcttggtt
    23941 tattctcttt aagactcaat ttggtcttcg tctccgctct gtcggtgaac atcctcaagc
    24001 agcggatacc ttgggaatca acgtctacaa gatgagatat ttagggatta ttatttcagg
    24061 ttttctaggt ggaattggcg gagcgattta tgcgcaatca atctcagtta acttttcagt
    24121 gacaactatt gttggacctg gatttatcgc ccttgctgcg atgatctttg ggaaatggaa
    24181 tccaatcggt gctatgcttt ctagtctctt ctttggactt tcacaaagtt tggctgttat
    24241 cggttctcaa ttgccgttcc tacaaggagt gccagcggtt tatcttcaaa ttgcacctta
    24301 tgttttgaca attcttgtct tagcagcctt ctttggaaaa gcagtcgcac caaaagcaga
    24361 tggtatcaac tacatcaaat caaaataagc atacaaaaaa acgtcagtcc aatgactgaa
    24421 ctgcccccca aaagttagac agaaaaaatc taacttttgg ggtgttttta
//
LOCUS       DAVKBC010000029        24349 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVKBC010000029 DAVKBC010000000
VERSION     DAVKBC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24349
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.029"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            299..1291
                     /locus_tag="VWX64_001370"
     CDS             299..1291
                     /locus_tag="VWX64_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9190835.1"
                     /translation="MAMIEVSCLRKDFVKIIKEPGLKGAIRSFIHPEKQIFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQENRQDYVKDIGVV
                     FGQRTQLWWDLALQETYSVLKEIYDVPDAVFQKRMDFLNDVLDLKEFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVNQLKETFGKMKTLTFELRPGQNHVVSQFVGISDIH
                     VTRKELLLNIQYDSSRYQTADIIQKTLSDFAIRDLKMTDVNIEDIIRRFYRKEL"
     gene            1293..2111
                     /locus_tag="VWX64_001371"
     CDS             1293..2111
                     /locus_tag="VWX64_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU9190836.1"
                     /translation="MVKLWKRYKLFISAGMQELITYRVNFFLYRIGDVMGAFVAFYLW
                     RAVFSSSHQSLIRGFSLSDMTFYIIMSFVTNLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTEIGFRWLVFVSVGLPFLIIIIGLKLLSGQPILQISLMTLTYLLSLILA
                     FLINFFFNICFGFSAFVFKNLWGSNLLKNSLVAFMSGSLIPLSFFPKIIADILYFLPF
                     SSLIYTPVMIIVGKYNISQMIQAVLLQLFWLLVMIALSQIIWKRVQSHITIQGG"
     gene            2113..2897
                     /locus_tag="VWX64_001372"
                     /pseudo
     CDS             2113..2897
                     /locus_tag="VWX64_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            3024..3176
                     /locus_tag="VWX64_001373"
     CDS             3024..3176
                     /locus_tag="VWX64_001373"
                     /inference="COORDINATES: protein motif:HMM:NF012457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190837.1"
                     /translation="MLHHFDTPEALHSNGDFLNWEILATLFTMLSSVLKNLQKLIIRQ
                     LSMKLV"
     gene            3468..3692
                     /locus_tag="VWX64_001374"
     CDS             3468..3692
                     /locus_tag="VWX64_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU9190838.1"
                     /translation="MLEVAKALNDFLGISYYMSDWMQAFDGSTEFIHNGKGEKDSSKY
                     QINGAGRCEVPVYVPKTDWDWIIYPQGIYD"
     gene            3696..3842
                     /locus_tag="VWX64_001375"
     CDS             3696..3842
                     /locus_tag="VWX64_001375"
                     /inference="COORDINATES: protein motif:HMM:NF012457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU9190839.1"
                     /translation="MRVKRDYPNYKIYITENGLGYKDEFVDNTVYDDGRIDYDYVKKH
                     LEVI"
     gene            4112..4990
                     /locus_tag="VWX64_001376"
                     /pseudo
     CDS             4112..4990
                     /locus_tag="VWX64_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            5238..5462
                     /locus_tag="VWX64_001377"
     CDS             5238..5462
                     /locus_tag="VWX64_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9190840.1"
                     /translation="MYQRIRDLREDHDLTQKFVANLLSFSHTNYAKIKRGEVVLTADV
                     LVQLFKLYDVSTDYLLGLTDCPDRIKRKIK"
     gene            5867..7639
                     /locus_tag="VWX64_001378"
                     /pseudo
     CDS             5867..7639
                     /locus_tag="VWX64_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            7744..8331
                     /locus_tag="VWX64_001379"
     CDS             7744..8331
                     /locus_tag="VWX64_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEU9190841.1"
                     /translation="MGGNPPIKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADLIIIGGGNTEKYIATYVNQEFKNYIDHM
                     LNKGAKVIGFSAGALLLGEKVYVSPNDNSDHQIKIKDGLGLFSQFLISVYYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            8438..8842
                     /locus_tag="VWX64_001380"
                     /pseudo
     CDS             8438..8842
                     /locus_tag="VWX64_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918778.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
     gene            9036..9275
                     /locus_tag="VWX64_001381"
                     /pseudo
     CDS             9036..9275
                     /locus_tag="VWX64_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9419..10648
                     /locus_tag="VWX64_001382"
     CDS             9419..10648
                     /locus_tag="VWX64_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9190842.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            10668..13364
                     /gene="ppc"
                     /locus_tag="VWX64_001383"
     CDS             10668..13364
                     /gene="ppc"
                     /locus_tag="VWX64_001383"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU9190843.1"
                     /translation="MSLQKLENYSNKSVVKEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWHNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    13447..13664
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13777..14781
                     /locus_tag="VWX64_001384"
     CDS             13777..14781
                     /locus_tag="VWX64_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9190844.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGVKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            14850..15716
                     /locus_tag="VWX64_001385"
     CDS             14850..15716
                     /locus_tag="VWX64_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190845.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVT
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            15713..16471
                     /locus_tag="VWX64_001386"
     CDS             15713..16471
                     /locus_tag="VWX64_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190846.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            16561..18321
                     /gene="dnaG"
                     /locus_tag="VWX64_001387"
     CDS             16561..18321
                     /gene="dnaG"
                     /locus_tag="VWX64_001387"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU9190847.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDATKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGKLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            18324..19433
                     /gene="rpoD"
                     /locus_tag="VWX64_001388"
     CDS             18324..19433
                     /gene="rpoD"
                     /locus_tag="VWX64_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU9190848.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            19447..19776
                     /locus_tag="VWX64_001389"
     CDS             19447..19776
                     /locus_tag="VWX64_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9190849.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            19891..20934
                     /gene="cpoA"
                     /locus_tag="VWX64_001390"
     CDS             19891..20934
                     /gene="cpoA"
                     /locus_tag="VWX64_001390"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU9190850.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            20950..22275
                     /locus_tag="VWX64_001391"
     CDS             20950..22275
                     /locus_tag="VWX64_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU9190851.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            22306..22482
                     /locus_tag="VWX64_001392"
     CDS             22306..22482
                     /locus_tag="VWX64_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9190852.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            22541..22675
                     /locus_tag="VWX64_001393"
     CDS             22541..22675
                     /locus_tag="VWX64_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU9190853.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            22739..24049
                     /gene="obgE"
                     /locus_tag="VWX64_001394"
     CDS             22739..24049
                     /gene="obgE"
                     /locus_tag="VWX64_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU9190854.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            24059..24217
                     /locus_tag="VWX64_001395"
     CDS             24059..24217
                     /locus_tag="VWX64_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190855.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         7755 a         3923 c         5198 g         7473 t
ORIGIN      
        1 ttatccatta tggtgaaatt aaaaaaagtg atacctttta taacttagct atagttctag
       61 gtaactttaa aaagtaaatt tatatccatt tagaccaatt ttttactgtt tttataactg
      121 aaatatgtaa aggcccctta aaaaaatttt agtagtttat tttctgtgga tgtaaaacaa
      181 cattgtgagg ttattgtttt aagtgttcta ataattaaga ttaaaatagc tttatagtgg
      241 acaaaaactt ggatttgaac actgattacc atataaatag ataaaaggag agtaaagtat
      301 ggcaatgatt gaagtatctt gtcttcggaa agattttgtt aagataatta aagaacctgg
      361 cttaaaagga gccatacgtt cttttatcca tcccgaaaaa caaatttttg aagcggttaa
      421 ggatttatcg tttgaggttc caaagggaca aattttaggt tttattggtg ctaatggggc
      481 aggtaagtca acaacgatta aaatgttgac agggatttta aaaccgacat ctggtttttg
      541 tcgcattaat gggaagattc ctcaagaaaa tcgtcaggat tatgttaagg atattggtgt
      601 tgtttttggg caacgcaccc agctttggtg ggatttggct ttacaagaga catactcagt
      661 tttaaaagaa atttatgatg tccctgatgc agtatttcaa aaacgcatgg attttttaaa
      721 tgatgtttta gacttgaaag agtttattaa ggatcctgtt cggacactat cgttaggtca
      781 acgtatgaga gctgatattg cggcttcttt attgcataat cccaaagtcc tttttttaga
      841 tgagcccacc attggtttag atgtttctgt caaggataat attcgacgag cgatcacaca
      901 gattaatcaa gaagaagaga cgacaatact cttaaccact catgatttga gtgatattga
      961 acaattatgt gatcgtattt ttatgattga taagggacaa gagatttttg acggcactgt
     1021 aaatcaactg aaagaaactt ttggaaagat gaagaccctt acttttgaac tacgtccagg
     1081 tcaaaatcat gttgtctctc agtttgtagg gatttcggat attcatgtta cgcgaaaaga
     1141 gttgctacta aatattcaat atgatagctc gcgttatcaa acagctgata ttatccaaaa
     1201 aaccttgtct gattttgcca ttcgagattt aaagatgacc gatgtaaata ttgaagatat
     1261 tatccgtcgt ttctaccgaa aggagcttta agatggttaa attatggaaa cgctacaaac
     1321 tatttattag tgctggaatg caggaattga ttacttatcg tgtcaatttt tttctttacc
     1381 gaattgggga tgttatggga gcatttgttg ctttttactt atggagagcc gttttcagtt
     1441 cgtcgcatca atccttgatt cgaggattta gcttatctga tatgactttt tatatcatca
     1501 tgagttttgt gactaacttg ctaacaaaat cggatagctc atttatgatt ggcgaggaag
     1561 taaaggacgg ttcaattatt atgcggttgc ttcgtccggt tcattttgca gcttcttatc
     1621 ttttcacaga gattggattt aggtggttag tctttgttag tgttggcttg ccgtttttaa
     1681 tcataattat aggcttaaaa ctcttatccg gacaacctat cttgcaaatt tctctaatga
     1741 ccttgaccta tcttcttagc ttaatattgg cttttttgat taattttttc tttaatattt
     1801 gttttgggtt ttccgctttt gtttttaaaa atttgtgggg gtcaaatctt ctaaagaatt
     1861 ctttggttgc ctttatgtct ggtagtttga ttcctttgtc tttttttcca aaaatcattg
     1921 cggatatatt atatttttta ccattttcat ctttaattta tacgccagtg atgattattg
     1981 taggaaagta taacattagt caaatgattc aagctgtctt gctacaatta ttttggttgc
     2041 ttgttatgat tgctttgtcc caaattattt ggaaacgtgt acagtcccac attactattc
     2101 aaggaggtta gtatgaagaa atatcaacgt atgcacttga tttttatcag acaatacctc
     2161 aagcaaattg tggagtataa ggttgacttc gttgttggcg ttttaggcgt tttttaacgc
     2221 aagggttaaa cctgttattt cttaatatta tatttcaaaa catcccatca cttgatgggt
     2281 ggagttttca gcagattgcc tttatctatg gcttttccct aattcccaag ggaattgatc
     2341 atctcttttt tgataattta tgggctctag ggcaacgcct ggttcgtaag ggcgaatttg
     2401 ataaatacct gacaagaccc attaatcctt tatttcatat tctagtagaa acttttcaaa
     2461 ttgatgcttt aggtgaattg ttagtaggta tttcattact atcagcaacg gtaaccagct
     2521 tgacttggac ttggacaaag gtttttatct ttttaattag tatacctttt gccaccttga
     2581 tttatacttc cttaaaaatt gcaacagcca gcatagcttt ttggaccaaa caatctgggg
     2641 cagtgattta cattttttat atgttcaatg attttgcaaa atatccggtt gtcatctaca
     2701 attcattttt acgttggttg ataagtttta ttattccttt tgcttttaca gcctactacc
     2761 cagctagcta tttcttgaaa gataaggatg gattgtttaa tattggtgga ttaatcctta
     2821 tttcattaat atttttcacc atatcattaa aattatggaa caaaggtttg gatgcatatg
     2881 aaagttctgg atcatagctc ctaaagattt caatatctat agattataat tgttatggat
     2941 attgcaaaaa gtcaatgaaa aggagttgaa ttttatcata atttttttca gagtgttata
     3001 agcgtggcgt tgaattattt gtaatccttc atcattttga tactcccgaa gcattgcatt
     3061 ctaacggtga tttccttaat tgggaaatat tggccacgtt gttcactatg ctgagttctg
     3121 ttttaaagaa tttacagaag ttaattatta gacaactttc aatgaaattg gtctaatcgg
     3181 tgatggacaa tatcttgtta gtaaatttcc atcaggtatc aaatatgatc ttgtaaaagt
     3241 ttttcaatca caccatagca tgatgatttc ctaaactcgt gctgttaaac tgtttaaagg
     3301 tggtagtcac aagggtgaga ttagtgtggt tcatgctctt cagacaaaat aaccatttga
     3361 taaaaataac cctgatgatg ttcgtgcagt agaacttgaa gacctcatcc ataataaatt
     3421 catttttgat gcaacttatt taggtggtta ctcagagaaa ttgttaagtg ttagaagtag
     3481 ctaaagcttt gaatgacttc cttggtatta gctattacat gagtgactgg atgcaagcct
     3541 ttgatggatc aacagaattt attcataacg gtaaaggtga gaaagatagc tctaaatatc
     3601 aaattaatgg agctggacgt tgtgaagtac cagtttatgt acctaagaca gattgggact
     3661 ggattattta tcctcaaggt atatatgatt aaatcatgcg tgtaaaacgg gattatccaa
     3721 attataaaat ttatatcact gaaaatggtt tgggatataa agatgaattt gttgataaca
     3781 ctgtttatga tgatggtcgt atcgattatg attatgtgaa gaaacactta gaagtgattt
     3841 aagatgcgat tgcagatggt acaaatatta aaggggagtt tatttggtcg ttgatggatg
     3901 ttttcttatg ttcaaatggc taagaaaaat gttatagtct cttctatctg gactttgaga
     3961 cacaagaata ttactctaag aaagagtgcc tactagtaca accaagtagc agaatctcaa
     4021 cttattgaat agtatatata atttctaaca caagataaga gtgtgggttt aagacagacg
     4081 ctcttgtttg gtatcgggga ggaaaaatca aatagttatt gaattaaaaa atgagcgatt
     4141 gatagtgcag ttttcgtagt ttgacggtgc cttatcttct attaaagata aggatggtgt
     4201 agaataccta tggcaaggta atccagaata ttggagtgac caagcacaag ccctatttcc
     4261 aatttgtgta agtgtaagag atgattaagt tctcgtagaa ggggaatata ggaatattcc
     4321 tgtacgtgga ttagtaagaa aataaaattt tacatataag aagataggtg aatcgtcaat
     4381 ttcttttagc tataaatcta acgtgtagac tcttcaagaa tttccatatc acttagtttt
     4441 gaatataatt tatcgcttgt atgactctac aaaaactacg gaatatcagg taacgtttag
     4501 tgaagttgaa cgttctattc cttactttat ggaggtcacc caggatttaa ttgccctcta
     4561 gaaaataacg ataaatacga agattatcat ttagaatttt ctgaatatta aatatgtagc
     4621 attccaaaga gtttcccaga tactggatta cttgatttac aagatagaac cccttttctt
     4681 gaaaatcaaa atgaattaga tttggattat tctttgtttt cacacgatgc tattacccta
     4741 gatcaactaa agtcatgtag tgtcagttcg aaatctaaaa aagtaataag ggaattaagg
     4801 tggattttaa agattttcca catttaatta tttggtttac cactaatcaa agtccattta
     4861 tagccttaga gctatggagt ggattatcaa catcattaga ggaatcagat atattggaag
     4921 agaagcaggg gttacatttg tagaaccgag tcaaactagc attaaatcat tcgatattac
     4981 tattttgtaa attaaagtta gctgaacgga atctaaagat agggacttta gaaatttaca
     5041 aaaatccaat ataaaatttg tataatctaa tgtaaggtgg tctgaagtag tagtcaatct
     5101 agaatatatt caaaatagta ttgaaatatt tataaaaata attgttggtt ttaactaaac
     5161 aataattact gtcatattat gacaatttcc cagctttttt ctgaaagtga catatacttt
     5221 tcttaggaga aagctagatg taccaacgga taagagattt gagggaagat catgatctca
     5281 ctcaaaagtt tgttgcaaat ttactttcct tttctcatac aaactatgca aaaattaaga
     5341 gaggagaggt tgtcttaacg gcagatgttc ttgtgcagct ttttaaactc tatgacgtta
     5401 gtacggatta cttattagga ctaacagatt gtccagatag gataaagcgt aaaataaaat
     5461 agtctctcct tgatttgttc attgacaatt gaataaaccg aggtgggact tttttatttg
     5521 tcgagcaatt tagtgagata cgccgtgata ggagcgaaaa ttattagcta taaaatagag
     5581 tggttctcta tctgccatga ccacaaataa ggacaatgat acttctgaac gttcagactg
     5641 ctatcgtaaa aggacagcgg gtgagacgcc catgaatgat ctaaccagtc atacccacgg
     5701 aggaaattat agaatagcac gttatcagga ggaaaaattt tggaacaaac agttgtaaaa
     5761 tatagtctgc agttatcaat gcttaatttt ttatattcta atttatttga acgcggtaat
     5821 atagaatcaa aaggaggaat ttcaatttga aaaaaataat gttgaaataa taaaagctga
     5881 ttctttagtt cgacgtagag gtgtcaatgt agaaagacat ttaaaaagag ttgctgctta
     5941 ttgccgagtt agctctgata gcgaagatca gaagaacagc tatgaatctc aggtgagaca
     6001 ttataaagat tatatctctc agcggtcgga ttgggaacta gcaggtatct atgcagatga
     6061 ggggatttca ggaacacaag taggaaagag acaagatttt caacgattaa taaatgattg
     6121 tgtaaatgga gaaatagatt acattgtcac aaaagcaatt gctagatttg caaggaatac
     6181 tctagatact ttgaagtatg tcagaatgtt aaatgatatg caaattggag tatattttga
     6241 ggaagaaaac atagatatct taacaatgga tggagaattg cttctgacta ttctaagctc
     6301 cgttgcacaa caagaagtag aaaatacttc tgcccatgtg aaaaaaggat taaaaatgaa
     6361 gatggaacgt ggtgaattgg ttggctttca agggtgccta gggtatgatt atgatgtaga
     6421 aaccaagcag atttcaatta ataaaaaaga atccaaaatt gttcgttaca tttttgaaag
     6481 gtatctagaa ggtattggag gaaaagtaat tgcaagagaa cttgatgaac ttggttataa
     6541 atcgccaaga ggattagaac attggaatga tacaacagtt ctaggaatca taaagaatga
     6601 aaaatataaa ggtgatattt taataggaaa aacttttaca gttgacccaa taagcaagag
     6661 aaggttgagt aattttggag aagaagataa gtactatatc aaagataatc atgaacctat
     6721 aatatctaaa taagattttg aaaaagctca ggagataaga ctgcgtcgag caggaaataa
     6781 gaagactgct gcaaatgtaa atggcaagcg tgaacgctat tcaaaaatgt atgcttttag
     6841 tagcatgtta gaatgtggtt tttgtggttc aatattatct agaagaagtt gtcactgccg
     6901 ttcagattat cgcaaggttg tgtggcactg tgttacatcg ataaagaaag gaaagaaatt
     6961 ttgtaagcat agtaaaggat tagaaaagct cgctattgag ggggctttca tggaagctta
     7021 cagacaactc tatcattcaa atgaaaactt aatgacagac ttacttgaaa cgattgaatc
     7081 tgaattgaat gacaatagcc ttaacaagga actaaaaagg attacaaaca aacttcgaac
     7141 attactaaaa aaagaggaaa atcttgtaaa tctaaggctc gaagggaaaa ttagcgatac
     7201 catatacgat gaaaaataca atgaaatttc ttcagaaaaa gagtttctag cagaagagaa
     7261 ggtaaatatt gaaacaacct taaaatcaga aatcgatgta aagaaaagac taactgagtt
     7321 taagcacttg ctatcttcgc aaaaaatgct tacggagttt gatcgtgcag tttttgaaag
     7381 tattgttgag aaaattattg taggtggagt taatagcaac ggagaaattg atcctgcaat
     7441 gttaaccata atattcaaaa caggtgaaac tcaaaacaag gatggtaaac aatttaaaag
     7501 taaacgtaaa aatgctaaac tagaaacaga taaattgtgt cctcaaaaca gtgacgagga
     7561 taaaaaattg tattctcaag gaacagacaa cacacgtgga gtgtgtagtg ttgctggttc
     7621 gatcttagtc agtcaataaa atgatatgtt ttaaaaaaat tataatttcg aaacgtgaat
     7681 aaacttgttt aaactttatg tatctttaga aagtgtgata acttgaaaga acaaattttt
     7741 ttgatgggtg ggaatccccc aataaagaaa tatagtattg ttgataaaat tgtattatca
     7801 accaagatta aaagaattat catttttaca gtttttcgag aaaattggga accgtacatg
     7861 aaaaagtaca cggaagtttt tcaaagtcaa tttcctaatc taaacattga ttacttgctc
     7921 ctggacactg agcagattga tcttgatagc tatctagatg ctgatctaat tatcatcggt
     7981 ggtggaaata cggaaaaata tatagctact tatgtcaatc aggagttcaa aaattatatt
     8041 gatcatatgc ttaacaaagg ggcgaaagtt atagggtttt ctgcaggagc cctattatta
     8101 ggagaaaaag tctacgtctc acctaacgat aattcagatc atcagataaa gataaaagat
     8161 ggattaggac tctttagtca gtttttaatt agtgtctatt atgattcatg gaatgataaa
     8221 gcaaataagg atagagctga agaactcgtt aatgttccca taattccact aaatgatcat
     8281 tcatgtcttg tattagataa acttggaaac attattgaga aaattgacta gtttccatta
     8341 tctaaatctt gatttaggta actaaagtgt agacgaactg gataggttac tagtgaaaac
     8401 tgcaaaaagt gttgtgaaat gaatcggaga gtgcttgatg gattttagta gtaagatagc
     8461 cataaataca ggctggtcag atgataaaaa atattgtgtg acagatcaaa atcagcaaaa
     8521 atattttttg cgtgtttctg ataaggagaa gttagattct aaaaaatttg aatttgatat
     8581 gatggggaaa gtagcttctc ttggagttcc tatgtgtaaa ccaattagca ttgaactctg
     8641 cgatgacgaa gtacattctt tacacgaatg gatagacgga agagatgcaa tagatagcat
     8701 tttaacttat tcagaaaacc aacaatacac atatggtgta gaagcaggaa agatacttag
     8761 aaagattcat acaattcctg ctacagaagt ttgtgaagat tgggaaatct tttttaatct
     8821 aaaaattgat gataaaatct ccaacgaaat gatatggtaa gtccgaaacg ctcagtgtgt
     8881 aagcttgttg ctaaaagcgt aaaaaccttg gaacgaaagg aataatagac ttcctgcgaa
     8941 acaaaaatac aatacaataa aactatggat gatgaagcaa gtaaacaatt aagcgatagc
     9001 cgtttcaaga gccttgtagg tgttcagcgc acgagatgtt agctgtgtta aaaacagctt
     9061 atcaacgcaa cgtaaacgcg caaaaggtgg acgaaaaacc aaattaagcc tagacgatct
     9121 cctcatggta actattcaat acatgcgaga atagcgcact tatgaacaaa ttgcggctga
     9181 ttttggcatt cacgaaagca acataattag tcggaggtca atggattgaa gcaactctta
     9241 ttcaaaatgg ttttacgatt tcaaattctg ccttaattct gtaaaaacag taaaattcga
     9301 aggattgtaa ggtgagagtt tttttctttc tgaaaaaatg gtataatagc aatcaaaact
     9361 agaaaataaa acggaatttg gaacagattt gtctgtatcc tagtagagtg gtgatactat
     9421 gaagattagt aagaggcact tattaaatta ttccatcttg attccctact tgcttttatc
     9481 tattttgggc ttgattgtgg tctattcgac caccagtgct attttaattg aagaaggtaa
     9541 gagcgccttg cagttggttc gaaaccaagg aatcttttgg attgttagtt tgatactgat
     9601 tgccttaatt tataaattga gactagattt tttgagaaat gagcgactaa tcattttagt
     9661 tatattaata gaaatgcttt tattgttctt ggctcgtttt attggtattt ccgtaaacgg
     9721 ggcatacggt tggatttcgg ttgcaggagt aactattcag ccagctgagt acttaaaaat
     9781 cattattatt tggtatttag ctcaccgatt ctccaaacag caagaagaaa tagctactta
     9841 tgattttcaa gttttgactc aaaatcaatg gcttccccgt gcttttaatg attggcgatt
     9901 cgttctccta gttctgattg gaagtttggg aattttccct gatttaggaa atgcgactat
     9961 tttagtcttg gtttccttga ttatgtatac agttagtgga atcgcttatc gctggttttc
    10021 aaccattctg gcactcgtat ctgccacttc tgtctttgtc ttgaccacta tcagcctaat
    10081 cggtgttgag accttttcaa aaattccagt atttggctat gtagccaagc gctttagtgc
    10141 cttttttaat ccttttgccg atcgtgctga tgcaggtcac cagttagcta attcttattt
    10201 tgccatggtc aatggcggtt ggtttggtct aggtcttgga aactcgattg aaaaacgagg
    10261 ttatttgcca gaagctcata cagactttgt cttttctatc gtgattgaag aatttggctt
    10321 tgttggtgcc agtcttattt tagctctctt gtttttcatg attttgcgga ttatcttggt
    10381 cggtatccga gcggagaatc ctttcaatgc catggttgca ctcggtgtcg gagggatgat
    10441 gttggttcag gtatttgtca atatcggagg gatttcgggc ttgattccat ctacaggagt
    10501 gactttcccc ttcttatccc agggtggaaa tagtcttcta gtcttatcag tggcagtagc
    10561 ctttgtctta aatattgatg ccagtgaaaa acgcgctaag ttgtaccgag aattggaaaa
    10621 tcaaccaatg aaccttctgt tgaagtagga taaagaaagg atagtttatg tctcttcaaa
    10681 aattagaaaa ttatagtaat aaaagtgttg tgaaagaaga agtcttgatt ctaacagaat
    10741 tactggaaga tattactaaa aatatgcttg ccccagagac ctttgaaaaa ataatacagt
    10801 tgaaagaatt atcaacgcag gaagattatc aaggtctaaa ccgtctagtg actagcttat
    10861 caaatgatga aatggtctat atttcacgct atttctctat cttacctctt ttgattaata
    10921 tttcagagga tgtggattta gcttatgaaa tcaatcatca aaataatatt gatcaggact
    10981 atttaggtaa attatctaca acgattaaat tggtagcaga aaaggaaaat gccgttgaga
    11041 tcctagaaca cttgaatgtt gtccctgtgt tgacagccca tccaacacaa gtgcaacgca
    11101 aaagtatgtt ggatttaaca aatcatattc atagtctttt gcgtaaatac cgtgatgtta
    11161 agttggggtt aatcaataaa gataaatggc acaatgattt gcgtcgttac atcgaaatta
    11221 tcatgcagac agacatgatt cgtgagaaaa aattaaaagt gactaacgaa atcacgaatg
    11281 ctatggaata ttacaacagc tcctttttga aagctgtccc tcatttgacg acggagtata
    11341 agcgcttagc gcaagcgcat ggtctgaatt taaaacaggc taaaccaatc accatgggta
    11401 tgtggatagg tggtgaccgt gatggaaatc catttgttac agcaaagacc ttgaagcagt
    11461 ctgcactcac tcagtgtgaa gtcatcatga actactatga taaaaagatt taccaacttt
    11521 atcgtgaatt ttctctttca actagcattg tcaacgtcag caagcaagtc agagaaatgg
    11581 ctcgtcaatc caaggataac tcgatttacc gcgaaaaaga gctttaccgt cgtgccttgt
    11641 ttgatattca atcaaaaatt caggcaacta aaacctatct gattgaggat gaagaagttg
    11701 ggactcgtta tgaaaccgcc aatgatttct acaaggattt gattgccatt cgagattctc
    11761 tactagaaaa taagggtgag tccttgattt caggtgattt tgtggaatta ttgcaggcag
    11821 tagagatatt tggtttttac ttagcgtcaa ttgatatgcg acaagactct agcgtctatg
    11881 aagcctgtgt ggcagaactc ttgaaatcag caggaattca ttctcgttat agcgagttga
    11941 gcgaagaaga aaagtgtgac cttctcttga aagaattaga agaagatccc cgaattcttt
    12001 ctgcgactca cgcagaaaaa tcagaattat tagcaaaaga attagctatt tttaagacgg
    12061 ctcgtgtttt gaaagataag ttgggagatg atgtcatccg tcagaccatc atttcacatg
    12121 caaccagcct ttctgatatg ctagaattag ctattctgtt aaaagaagta ggactggtgg
    12181 atacggaaag ggcgcgtgtt cagattgttc ccctttttga aacaattgaa gacttggatc
    12241 attcagagga aacaatgaga aaatatcttt ctcttagcct tgccaaaaaa tggattgact
    12301 cacgaaataa ctaccaagaa atcatgcttg gctactctga cagtaataaa gatggcggtt
    12361 acttgtcatc atgttggacc ctctacaagg ctcaacaaca attgactgct attggagatg
    12421 aatttggcgt taaggttacc ttcttccatg gtcgtggtgg tactgtcggt cgtggtggtg
    12481 ggccaaccta tgaagccatt acatctcaac cgctcaagtc tatcaaggat cgtatccgct
    12541 tgacggagca gggtgaagta attgggaata aatacggtaa caaagacgcc gcttactata
    12601 accttgaaat gctagtatcg gcagctatta accgtatgat tactcagaag aagagcgata
    12661 ccaatacccc aaatcgttat gaagccatta tggatcaagt agtggaccgt agttacgata
    12721 tctaccgtga tttggtcttt ggtaatgagc atttctatga ttatttcttc gagtcaagtc
    12781 caatcaaggc tatttcaagt tttaatattg gttctcgtcc agccgctcgt aagactatta
    12841 ctgaaatcgg tggattgcgt gccatccctt gggtattctc atggtcacag agtcgtgtta
    12901 tgttccctgg atggtacggg gttggttcaa gcttcaagga atttatcaat aaaaatccag
    12961 agaatattgc tatcttacga gatatgtacc aaaattggcc tttcttccaa tcgcttcttt
    13021 caaatgttga tatggttttg tcaaaatcaa atatgaatat tgcttttgaa tatgctaaac
    13081 tttgtgaaga cgagcaagtt aaggccatct atgagactat tttaaatgaa tggcaagtta
    13141 ctaagaacgt tatcttggct attgaaggac atgacgaact cttagctgac aatccatatc
    13201 taaaagctag tctggattac cgtatgcctt actttaatat tctcaactat attcagttgg
    13261 agttgattaa acgccaacgt cgtggagaat tgtccagtga tcaagaacga ttgattcata
    13321 tcacgatcaa cggaattgcg acaggattgc gtaattcagg ttgataattt tcaagagtga
    13381 atgctaaaag tgaatatcaa aaaaattcta atagactatt gacaagtagt ttaaaaatga
    13441 tataatttaa ccattcagaa aagtaatcat acaaactttt tagagagtct gtggtagctg
    13501 aaaacagata agtggcgatg atgaaaattg ggctgaatgc tatttagaat ttgaaattat
    13561 aaaaattcgg taagcacacc ttacagtgca tctcgttatt gcgagactga gcgataggga
    13621 aattccctat aattgaggtg gtaccgcgca tcgacgtcct cacacaagtt ttttgtgtga
    13681 ggattttttt gatggaggtt agtatggaaa gaaaacgatg gcgtcgcttg tttagataag
    13741 tgaaatatgt taaaggaaat aaaaaggaga aacagaatga aaaataaacg tttaattgga
    13801 attattgctg cattagcagt cttagtagca ggaagcttga tttattcttc aatgaataaa
    13861 tcagaagctc agaataataa ggatgagaag aaaataacca agattggtgt gcttcaattt
    13921 gtgagccatc catcccttga tttgatttat aaagggatcc aagatggact tgcagaagaa
    13981 ggatataaag atgatcaagt taaaattgat tttatgaact cagaaggtga ccaaagtaag
    14041 gttgcgacaa tgagtaaaca attggttgca aatgggaatg accttgtggt tggtatcgca
    14101 acaccagcag cccaagggtt ggctagtgca acaaaagacc taccggttat catggccgct
    14161 attacagacc caattggtgc taacttggtt aaagatttga aaaaaccagg tggcaacgtt
    14221 acaggggtat ctgaccacaa tccagctcaa caacaagttg aactcatcaa ggctctgaca
    14281 ccgaatgtga aaacaatcgg agctctttac tcaagtagcg aagacaattc aaaaacacag
    14341 gtcgaagaat ttaaggctta tgctgaaaaa gcaggtctga cagtggaaac atttgcagtt
    14401 ccttcaacaa atgaaattgc ctcaactgtc actgttatga ctagcaaggt agatgctatt
    14461 tgggttccaa ttgataacac cattgcatca ggatttccaa cggttgtctc tagcaatcaa
    14521 agttctaaga aaccaattta tcccagtgcg acagctatgg tagaagtagg tggtttggca
    14581 tcagttgtaa ttgaccaaca tgaccttggt gtggcaacag gtaaaatgat tgtgcaagtc
    14641 ttgaaaggtg taaaaccagc cgatacccca gtcaatgtct tttcaactgg taagtcagtc
    14701 atcaataaaa aaatagcaca agaactaggt attactattc ctgagtctgt tctcaaagaa
    14761 gcaggacaag tcatcgaata aataaggtag ggaggaggag actcttccca ttttttaaaa
    14821 agatgaatat agaaaggatt aaataaaata tgattgtttc cattatttct caaggatttg
    14881 tctgggctat tctaggtctg ggaatcttta tgacatttag gattttaaac tttccagata
    14941 tgacgacaga aggttccttc cctcttgggg gagctgttac tgtcactttg ataaccaaag
    15001 gcgtgaaccc atttttagcg acacttgttg ctgtaggagc aggttgtttg gctggaatgg
    15061 cagcaggcct tctttataca aaagggaaga tcccaacctt gctctcaggg attttggtga
    15121 tgacttcttg tcactcaatc atgctcttga ttatgggacg tgcgaattta ggcctgcttg
    15181 gaaccaagca aattcaggat gttttgcctt ttgattcgga tttgaatcaa ctcttgacag
    15241 gtctcatctt tgtgagtatt gttattgctc tcatgctctt tttcttggac actaaactcg
    15301 gacaagccta tattgctaca ggggataatc ctgatatggc tagaagtttc gggattcata
    15361 ctggacgcat ggagctcatg ggcttggtct tatcaaatgg tgtgattgcc cttgcaggtg
    15421 ccctcattgc tcagcaagaa ggctatgccg atgtgtctcg agggatcggg gttatcgttg
    15481 tggggcttgc aagtttgatt attggagaag ttattttcaa gagtttgagc ttggcagagc
    15541 gtttggttac tatcgttgta ggttctatcg cttatcaatt tttagtgtgg gcagttatcg
    15601 cacttggctt taatacaagt taccttcgtt tatacagtgc tttgatttta gcagtctgcc
    15661 tcatgattcc aacatttaag caaacaatct tgaaaggagc caagttaagc aaatgacagc
    15721 aattgtagaa ttaaaaaatg caaccaaaat cgttaaaaat ggctttgatg aagaaaagat
    15781 tattttaaat gatgtttctt tagaaatttt tgaacgggac tttattacga ttttgggcgg
    15841 aaatggtgct ggaaaatcaa ccctctttaa cactatagca gggaccttat cactaactag
    15901 tggaactatc cgtattttag gtgaagatct cactaagttt tcacccgaga agcgtgccaa
    15961 gtacctgtct cgtgtcttcc aagatccaaa gatggggaca gctccccgta tgacggtcgc
    16021 tgaaaatctt ttaatcgcca agtttcgtgg tgaaaagcgt ggattgttac cacgacgctt
    16081 gactagctat aaggatgaat ttcaggcaac cattgaaaaa gtaggaaatg gtcttgagaa
    16141 acacttgaat acaccgattg agttcttatc aggtggacaa agacaggctt tgagtctctt
    16201 gatggcaacc ttgaagcgac ctgaattact cctgttagat gagcatactg ctgccctgga
    16261 tccaaagact agtgttgctt tgatggaatt gacagatgaa tttgttaaga aagatcagct
    16321 aacagccctt atgattactc atcatatgga agatgctctc aaatacggca atcgcttgat
    16381 tgtcatgaaa gaaggacgga ttatccaaga tttaaaccaa gaagaaaaag caaaaatgaa
    16441 aatctctgat tattatcaac tctttgaata aagtagggaa aatgagtgaa atggtttact
    16501 ttttttctga aataaagtat actatataaa gtaaactatg ataacatgga ggtattgtgt
    16561 atggttgaca aacaagtcat tgaagaaatc aaaaacaatg ccaacattgt ggaagtcata
    16621 ggagatgtga tttctttaca aaaggcagga cggaactatc tagggctctg tccttttcat
    16681 ggtgaaaaaa caccttcttt caacgttgta gaggataagc agttttacca ctgttttggt
    16741 tgtggtcgct caggtgatgt ctttaaattc atcgaggagt accaaggggt tacctttatg
    16801 gaggctgtcc aaatcttagg tcagcgtgtc gggattgagg ttgaaaaacc gctttatagt
    16861 gaacagaagc cagcctcgcc tcaccaagct ctttatgata tgcacgaaga tgcgactaaa
    16921 ttttaccatg ctattctcat gacaacgact atgggcgaag aggccagaaa ttacctttat
    16981 cagcggggtt tgacagatga agtgcttaaa catttttgga ttggtttagc acctccagaa
    17041 cgaaactatc tctatcaacg tttgtctgat cagtatcgtg aagaggattt actggattca
    17101 ggcctgtttt atctctcgga tgccaatcaa tttgtagaca cctttcacaa tcgcattatg
    17161 tttcccctga caaatgacca aggaaaggtc attgccttct caggtcgtat ctggcaaaaa
    17221 acggattcac aaacttctaa gtataaaaac agccgatcga ctgcaatttt taacaaaagt
    17281 tacgaattat atcatatgga tagggcaaaa aaatcttctg gaaaaactag tgagatttac
    17341 ctgatggaag gattcatgga tgttattgca gcctatcggg ctggaatcga aaatgctgtg
    17401 gcgtcgatgg gaacggcctt gagtcgagag catgttgagc atctgaaaag gttaaccaag
    17461 aaattggttc ttgtttacga tggagataag gctgggcaag ccgcgatatt gaaagcattg
    17521 gatgaaattg gtgatatgcc tgtgcaaatc gttagcatgc ctgataactt ggatcctgat
    17581 gagtatctac aaaaaaatgg tccagaagac ttggcctatc tattaacaaa aactcgtatt
    17641 agtccgattg agttctacat tcatcagtac aaacctgaaa acagtgaaaa tctgcaggct
    17701 cagattgagt ttattgaaaa aatagctccc ttgattgttc aagaaaagtc catcgctgct
    17761 caaaacagct atattcatat tttagctgac agtctggcgt cctttgatta tacccagatt
    17821 gagcagattg ttaatgagag tcgtcaggtg caaaggcaga atcgcatgga aagaatttcc
    17881 agaccgacgc caatcaccat gcctgtcacc aagcagttat cggctattat gagggcagaa
    17941 gcccatctac tctatcggat gatggaatcc cctcttgttt tgaacgatta ccgtttgcga
    18001 gaagactttg catttgctac acctgaattt caggtcttat atgacttgct tggccagtat
    18061 ggaaagcttc ctccagaagt tttagcagag cagacagagg aagttgaaag agcttggtac
    18121 caagttttag ctcaggattt gcctgctgag atatcgccgc aggaacttag tgaagtagag
    18181 atgactcgaa acaaggctct cttgaatcag gacaatatga gaatcaaaaa gaaggtgcag
    18241 gaagctagcc atgtaggaga tacagataca gccctagaag aattggaacg tttaatttcc
    18301 caaaagagaa gaatggagta ataatggcaa caaaacaaaa agaagtaaca acatttgacg
    18361 tacaggtagc agaatttatc cgtaatcata agcaaaaagg gacagcaaca gatgatgaaa
    18421 tcaatgcaag tctggttatt ccttttacct tggacgctga tgggattgaa gatctcttgc
    18481 aacggattca ggatgcaggc atttctatca cagataacga aggaaatcca agtgcgcgtg
    18541 ttcttagcaa tgaagaagaa ccagaactca gcgatgagga cttgattggg tcaacttctg
    18601 ctaaggtcaa tgaccctgtc cgtatgtact tgaaagaaat aggggtcgtt cctctcttga
    18661 ccaatgaaga ggagaaagag ttggcactgg ctgttgaagc tggcgatatc gaagccaaac
    18721 aacgtcttgc ggaagccaat cttcgtttgg ttgtttccat tgccaaacgc tatgtcggtc
    18781 gtggcatgca gttccttgac ttgattcaag aaggaaatat gggcttgatg aaggcggttg
    18841 acaagtttga ctattctaaa gggttcaagt tttcaactta tgcaacttgg tggattcgtc
    18901 aggctatcac tcgtgctatt gcggaccaag ctcgtaccat ccgtatccca gttcacatgg
    18961 ttgaaactat caataaattg gttcgtgaac agcggaatct ccttcaagaa ttggggcaag
    19021 atccgacacc agaacagatt gctgaacgaa tggatatgac acctgataag gttcgtgaaa
    19081 tcttgaagat tgcccaagaa ccagtatctc ttgaaactcc tatcggtgaa gaggacgata
    19141 gccaccttgg agactttatc gaagatgaag tgattgaaaa tccagtggat tatacgactc
    19201 gtatcgtctt gcgtgagcaa ttggatgaaa tcttagatac tcttacagac cgtgaagaaa
    19261 atgttctgcg tctacgtttt ggactagatg atggaaaaat gcgcacactt gaagatgtgg
    19321 ggaaagtctt taacgtaact cgtgagcgta tccgtcagat tgaagcaaag gctttgagaa
    19381 aactacgcca accaagccgc agcaaaccgc ttcgtgattt tattgaagac taagagtgag
    19441 gaaaatatgg cttatacaga agagcaaatt gaaaacatca aaacacggat tttaacagcc
    19501 ttggaagaag tcatcgaccc tgagttggga atcgatattg tcaatcttgg tttgatctat
    19561 gagattcgtt ttgacggtga cacagggcaa acagagattg acatgacttt gacaactatg
    19621 ggttgtccct tagcagacct tttgacagac cagatttatg atgctatgat agaggttcca
    19681 gaagtaacgg atactgaggt taaattagtc tggtatccag cctggacagt tgaaaaaatg
    19741 agtcgctatg cccgcattgc cctaggcatt aagtaaacat ataaaagcat gtgagagact
    19801 gttggaaaag cgaggaaatt tcccctcttt tcctctagtc tctcctttct tttgctgatt
    19861 ttattcaaag aaaatgatat aatagtagtt atggagaaaa agaaattacg catcaatatg
    19921 ttgagttcaa gtgagaaagt agcaggacag ggagtttcag gtgcttaccg tgaattagtt
    19981 cgtcttcttc accgtgctgc caaggaccaa ttgattgtta cagaaaatct tccgatcgag
    20041 gcagatgtga ctcactttca tacgattgat tttccctatt atttatcaac cttccaaaag
    20101 aaacgctcag ggagaaagat tggctatgtg catttcttgc cagctacact tgagggaagt
    20161 ttgaaaattc catttttctt aaagggaatt gtgaaacgct atgtattttc tttttacaac
    20221 cggatggagc acttggttgt ggtcaatcct atgtttattg aggatttggt agcagctggt
    20281 attccacgtg aaaaagtgac ctatattcct aactttgtca acaaggaaaa atggcatcct
    20341 ctaccacaag aagaggtagt cagactgcgc acagatcttg gtcttagtga caatcagttt
    20401 atcgtagtag gtgctgggca agttcagaaa cgtaaaggga ttgatgactt tatccgtctg
    20461 gctgaggaat tgcctcagat tacctttatc tgggctggtg gcttctcttt tggtggtatg
    20521 acagatggtt atgaacacta taagaaaatt atggaaaatc cccctaaaaa tttgattttt
    20581 ccaggcattg tatcgccaga gcggatgcgc gaattgtatg ctctagcgga tcttttcttg
    20641 ttgcctagtt acaatgagct ctttcctatg actattttag aagctgcgag ttgtgaggct
    20701 cctattatgt tgcgtgattt agatctctat aaggtgattt tggagggaaa ttatcgggcg
    20761 acagcgggta gagaagagat gaaagaggct attttggaat atcaagcaaa tcctgctgcc
    20821 ttaaaagatc tcaaagaaaa ggctaagaat atttccagag agtattctga agagcatctg
    20881 ttacaaatct ggttggactt ttatgagaaa caagccgctt tagggagaaa gtaaaaagtg
    20941 aggtaatcta tgcgaattgg tttatttaca gatacctatt ttcctcaggt ttctggtgtt
    21001 gcgaccagta ttcgaacctt gaaaacagaa cttgaaaagc agggacatgc tgtttttatc
    21061 tttacgacga cagataagga tgtcaatcgc tacgaagatt ggcaaattat ccgcattcca
    21121 agtgttcctt tctttgcttt taaggatcgt cgctttgcct accgaggttt tagcaaggca
    21181 cttgaaattg ctaaacagta tcagctagat attatccata ctcagacaga attttctctt
    21241 ggcctgttgg ggatttggat tgcgcgtgaa ttgaaaattc cagtcatcca tacctatcac
    21301 acccagtatg aagactatgt ccattatatt gctaagggga tgttgatccg accgagtatg
    21361 gtcaagtatc tggttagagg tttcctgcat gatgtggatg gggttatttg ccctagtgag
    21421 attgtccgtg acttgctatc tgattataag gtcaaggttg aaaaacgggt cattcctact
    21481 gggattgaat tagccaagtt tgagcgtccg gaaatcaagc aggaaaattt gaaagaactg
    21541 cgtagtaaac tagggattca agatggtgaa aagacgttgc ttagtctttc gagaatctcc
    21601 tatgaaaaaa atattcaagc agttttagca gcctttgctg atgttctgaa agaggaagac
    21661 aaggttaaac tggtagtagc tggggatggc ccttatctga atgacctcaa agagcaagcc
    21721 cagaacctag agattcaaga ctcagtcatc tttacaggga tgattgctcc tagtgagacg
    21781 gctctttact ataaagcggc ggatttcttc atttcggcat cgacaagcga aacgcaaggt
    21841 ttgacctact tggaaagctt agccagtgga acacctgtca ttgctcacgg aaatccttat
    21901 ttgaacaacc tcatcagtga taaaatgttt ggaaccttgt actatggaga acatgatttg
    21961 gctggtgcta ttttggaagc cctgattgca acaccagaca tgaacgagca taccttatca
    22021 gagaaattgt atgagatttc agctgagaac tttgggaaac gagtgcatga gttttatctg
    22081 gatgccatta tttcaaataa cttccagaaa gatttggcta aagatgatac ggtcagtcag
    22141 cgtatcttta agacagtttt gtatcttcag caacaggtgg ttgctgtacc tgtaaaagga
    22201 tctagacgca tgttgaaggc ttcaaaaaca cagttgatca gtatgagaga ctattggaaa
    22261 gaccatgaag aatagaaaga ggaacagcta tgaaaaaaac aattaatgag aagcggtcgt
    22321 gataaaaaga ttgcgggtgt ttgtgctggg gtggcccatt atctggatat ggatccgact
    22381 atcgttcaag tcatttgggg tgttcttact tgctgttacg gagctggaat tgtagcttac
    22441 attattttat ggattatcgc accagtagca actgactatt gaaaactagc tcaattcatg
    22501 ctaagataat agaaaataga atgtaacgaa ggagagaaaa atggcatttg gagataatgg
    22561 aaatcgtaaa aaaactatgt ttgagaaaat aaccttgttt atcgtgatta tcatgctagt
    22621 agcaagttta ttgggaattt ttgcaactgc aattggtgcc ctcagtaatc tataaaatag
    22681 attcaagaaa atttagtgac tgggatttcc cagccctttt ttaaagtgag aagaaataat
    22741 gagtatgttt ttagatacag ctaagattaa ggtcaaggct ggtaatggtg gcgatggtat
    22801 ggttgccttt cgtcgtgaaa aatatgtccc taatggaggc ccttggggtg gtgatggtgg
    22861 tcgtggaggc aatgtggtct tcgttgtaga cgaaggacta cgtaccttga tggatttccg
    22921 ctacaatcgt catttcaagg ctgattctgg tgaaaaaggg atgaccaaag ggatgcatgg
    22981 tcgtggtgct gaggacctta gagttcgagt accacaaggt acgactgttc gtgatgcgga
    23041 gactggcaag gttttaacag atttgattga acatgggcaa gaatttatcg ttgcccacgg
    23101 tggtcgtggt ggacgtggaa atattcgttt cgcgacacca aaaaatcctg caccggaaat
    23161 ctctgaaaat ggagaaccag gtcaggaacg tgagttacaa ttggaactaa aaatcttggc
    23221 agatgtcggt ttagtaggat tcccatctgt agggaagtca acacttttaa gtgttattac
    23281 ctcagctaag cctaaaattg gtgcctacca ctttaccact attgtaccaa atttaggtat
    23341 ggttcgcacc caatcaggtg aatcctttgc agtagccgac ttgccaggtt tgattgaagg
    23401 ggctagtcaa ggtgttggtt tgggaactca gttcctccgt cacatcgagc gtacacgtgt
    23461 tatccttcac atcattgata tgtcagctag cgaaggccgt gatccatatg aggattactt
    23521 agctatcaat aaagagctgg agtcttacaa tcttcgcctc atggagcgtc cacagattat
    23581 tgtagctaat aagatggaca tgcctgagag tcaggaaaat cttgaagaat ttaagaaaaa
    23641 attggctgaa aattatgatg aatttgaaga gttaccagct atcttcccaa tttctggatt
    23701 gaccaagcaa ggtctggcaa cacttttaga tgctacagct gaattgttag acaagacacc
    23761 agaatttttg ctctacgacg agtctgatat ggaagaagaa gcttactatg gatttgacga
    23821 agaagaaaaa gcctttgaaa ttagtcgtga tgacgatgcg acatgggtac tttctggtga
    23881 aaaactcatg aaactcttta atatgaccaa ctttgatcgt gatgaatctg tcatgaaatt
    23941 tgcccgtcag cttcgtggta tgggggttga tgaagccctt cgtgcgcgtg gagctaaaga
    24001 tggggatttg gtccgcattg gtaaatttga gtttgaattt gtagactagg agactggtat
    24061 gggagataaa ccgatatctt tccgagatgc ggatggtaat tttgtttccg ccgcagacgt
    24121 ttggaatgaa aagaaattgg aagaactatt taatcgtctc aatccaaatc gtgccttgag
    24181 attggcacga actaaaaagg aaaatccatc tcagtaaaga agctaaaaaa tcccgtgcct
    24241 catcagacac gggattttgt ggtacgacag gcatgtatag caaactgaat ctggaatagc
    24301 acagcatatc ttctaaaata tagtaaaatg aaatgagaac aggacaaat
//
LOCUS       DAVKBC010000030        23022 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVKBC010000030 DAVKBC010000000
VERSION     DAVKBC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23022
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.030"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            52..697
                     /locus_tag="VWX64_001396"
                     /pseudo
     CDS             52..697
                     /locus_tag="VWX64_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            694..912
                     /locus_tag="VWX64_001397"
     CDS             694..912
                     /locus_tag="VWX64_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190856.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(969..1253)
                     /locus_tag="VWX64_001398"
     CDS             complement(969..1253)
                     /locus_tag="VWX64_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU9190857.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(1307..2242)
                     /locus_tag="VWX64_001399"
     CDS             complement(1307..2242)
                     /locus_tag="VWX64_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU9190858.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            2346..2789
                     /locus_tag="VWX64_001400"
     CDS             2346..2789
                     /locus_tag="VWX64_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU9190859.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2905..3171
                     /locus_tag="VWX64_001401"
     CDS             2905..3171
                     /locus_tag="VWX64_001401"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU9190860.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            3168..3542
                     /gene="crcB"
                     /locus_tag="VWX64_001402"
     CDS             3168..3542
                     /gene="crcB"
                     /locus_tag="VWX64_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9190861.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDAVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3536..3865
                     /gene="crcB"
                     /locus_tag="VWX64_001403"
     CDS             3536..3865
                     /gene="crcB"
                     /locus_tag="VWX64_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9190862.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            3984..4331
                     /gene="rplS"
                     /locus_tag="VWX64_001404"
     CDS             3984..4331
                     /gene="rplS"
                     /locus_tag="VWX64_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU9190863.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            4373..4444
                     /locus_tag="VWX64_001405"
     tRNA            4373..4444
                     /locus_tag="VWX64_001405"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4406..4408,aa:Arg,seq:cct)
     gene            complement(4499..5305)
                     /gene="yidA"
                     /locus_tag="VWX64_001406"
     CDS             complement(4499..5305)
                     /gene="yidA"
                     /locus_tag="VWX64_001406"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU9190864.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETDTGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYTTKTNDESGVAHAIRTWVL"
     gene            complement(5318..6622)
                     /locus_tag="VWX64_001407"
     CDS             complement(5318..6622)
                     /locus_tag="VWX64_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU9190865.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQCNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            6694..7071
                     /locus_tag="VWX64_001408"
     CDS             6694..7071
                     /locus_tag="VWX64_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU9190866.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDRQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            7161..7493
                     /locus_tag="VWX64_001409"
     CDS             7161..7493
                     /locus_tag="VWX64_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU9190867.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILDRYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            7505..9076
                     /gene="ffh"
                     /locus_tag="VWX64_001410"
     CDS             7505..9076
                     /gene="ffh"
                     /locus_tag="VWX64_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU9190868.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKVLAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTSEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(9271..10554)
                     /locus_tag="VWX64_001411"
     CDS             complement(9271..10554)
                     /locus_tag="VWX64_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU9190869.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(10808..11521)
                     /gene="rsmG"
                     /locus_tag="VWX64_001412"
     CDS             complement(10808..11521)
                     /gene="rsmG"
                     /locus_tag="VWX64_001412"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU9190870.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            11615..12175
                     /locus_tag="VWX64_001413"
     CDS             11615..12175
                     /locus_tag="VWX64_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU9190871.1"
                     /translation="MTWIILGVIALIVVFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            12177..13076
                     /gene="htpX"
                     /locus_tag="VWX64_001414"
     CDS             12177..13076
                     /gene="htpX"
                     /locus_tag="VWX64_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU9190872.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRIFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINAPKKG
                     GGVQKLFYTHPPISERIERLKQM"
     gene            complement(13225..14784)
                     /locus_tag="VWX64_001415"
     CDS             complement(13225..14784)
                     /locus_tag="VWX64_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9190873.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIICRMTE
                     HGLKLVNLEDL"
     gene            complement(15023..15340)
                     /locus_tag="VWX64_001416"
     CDS             complement(15023..15340)
                     /locus_tag="VWX64_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU9190874.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYRPV
                     FEF"
     gene            15510..16052
                     /locus_tag="VWX64_001417"
     CDS             15510..16052
                     /locus_tag="VWX64_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU9190875.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16052..16681
                     /gene="nth"
                     /locus_tag="VWX64_001418"
     CDS             16052..16681
                     /gene="nth"
                     /locus_tag="VWX64_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU9190876.1"
                     /translation="MILSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVVFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            16892..17413
                     /gene="pyrR"
                     /locus_tag="VWX64_001419"
     CDS             16892..17413
                     /gene="pyrR"
                     /locus_tag="VWX64_001419"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU9190877.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            17432..18355
                     /locus_tag="VWX64_001420"
     CDS             17432..18355
                     /locus_tag="VWX64_001420"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU9190878.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQIPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFSGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            18405..19484
                     /gene="carA"
                     /locus_tag="VWX64_001421"
     CDS             18405..19484
                     /gene="carA"
                     /locus_tag="VWX64_001421"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU9190879.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            19797..22973
                     /gene="carB"
                     /locus_tag="VWX64_001422"
     CDS             19797..22973
                     /gene="carB"
                     /locus_tag="VWX64_001422"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU9190880.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELSVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAVVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         6688 a         4395 c         5160 g         6779 t
ORIGIN      
        1 aacgccttca aatcgttcta tagtaaaacg aaacaagaac agggcaaatc gatcaggaca
       61 gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatcta
      121 ctatatttcg tctgatgggc aaatcttata aagagattat agatctttta gactgtaatc
      181 aaacaacgat ttggcgaaat gtaaaaaaat atgaggagtt cggactcgac tctctccttc
      241 aagaaacacg tggtggtcgt aaccatgcat atatgacagt tgaggaagag aaagcctttc
      301 ttgcccgtca tttgaaggct acagaggcag gagaatttgt tacaattgat gccttatttc
      361 aggcttataa aaaggagtgt ggatgaacgc ctttttagaa gagctttcac aagcttatcc
      421 ttttattcgt tatggacaat gctatatggc ataaatcaag taccttaaat attccgacta
      481 atattgattt tacctttatt cctccataca caccagagat gaacccattg aacaagtgtg
      541 gaaagagatt cgtaaacgtg gatttaagaa taaagccttt cgaactttgg aagatatcat
      601 gaatcaactt caagatgtca tacaaggact ggagaaggag gtgataaagt ccatcgttaa
      661 tcggagatgg actagaatgc tttgtgaaag cagatgagta taagtcctcg ttttgaaacc
      721 ttagagcagg ccattgcctc caaagatttg gaaaaagtcc gagaagcttt taagaaaatg
      781 aattccactt ggaccatcaa tgaaagtgtg gttcgtgaca atagtacagc tcattatgga
      841 cgtgttgaaa cagctatttc cttcctgcct agtagcatgg aaaccgaacc tacagatgag
      901 tctggaacat gaaaacagca gttgatttca agaaacaaaa aagaacagcc gaaactgttc
      961 tcttatcatt atttgagacc gtattttttg ttgaaacgat ccacgcgtcc atctgcttga
     1021 gtgaactttt gacgtccagt gtagaatggg tgtgagtctg atgaaatttc cacacggatc
     1081 aatgggtaag tttcgccttc gaactcaact gtttcgttag agcgttttgt tgaaccgcta
     1141 aggaattggt aaccagtagt tgtgtccatg aagacaactg ggcgatattc tggatggata
     1201 tcttttttca ttttgcaata tttcctttct gccatggtct ctttgcgagc catagattgt
     1261 taccatacta gtctatcaga ttctgaaaag tttggcaagt attttatcag tttttaagca
     1321 agttttttaa cttttggtag atgatttcgt tttcttctag gctataggaa ttagcaccac
     1381 ttgctagagg gtggcctcca ccatcatgct ccttggcgat ttcattgata ggatggattt
     1441 tactgcgtaa gcgaactcgg tagtggccat cagcctgttc gacaaaaatt ccccagagac
     1501 tcactctgtc aatgcgtcca ggtgcaccga caatggctgc agtttcagca tcggttacat
     1561 tgtattgttt caagacttct tgactcagga taacgcgagc agcaccattt tcatccactt
     1621 ccagatggtc gtagatgtag ccttgcagtt tagcaatttt gtagctcata gtgtccattt
     1681 tgcgagtgag agccgcaaag tcaaagttat gttctctcaa ataagcagcc aggcgaagag
     1741 tccgtgcagt ggtagaaggg tagaggaagc gacctgtatc accgacaatt cctgcaaaga
     1801 gcaactcagc atcgcgatct gccaaggcta gttgggttgt ttgggcaaat agggtaatca
     1861 tctcgctagc gctacttgaa ctagtatcga cccaagacag gtcaccgtat acatcatcat
     1921 ttggatggtg gtcaatctta atgagaaaat caccttgact atagcgctta tcatcgatac
     1981 gagcagtatt agctgtatca cagacgatga caagtgcgcc ttggtaggct ctatcttcaa
     2041 caagatccat ctcagccatc caagtaagag ttggttcatc aaaaccgacg gctttgatgg
     2101 ttttttctgg gaaatgatgt tccagcaagg ctttcaatcc cacctgactt cccaaggcat
     2161 cagggtctgg tttcatatga cgatgaatga taatggtgtc gtattcttta attttttcta
     2221 aaatttgttg gcaaatctcc ataaataacc tcaattcttt ctcatttcat tgtagcacaa
     2281 gaatttttat ttttaaaatg aaaaagatgt gatataatgg agaaagataa attgaggagg
     2341 acgatatggc attagcaaaa attgtatttg ccagtatgac cggtaatacc gaagaaattg
     2401 cagatattgt agcagacaaa ttacgtgact tgggcttgga tgttgatgtt gatgaatgta
     2461 caactgttga cgcttcagac ttcttggaag cagacatcgc tatcgttgcg acctatactt
     2521 atggtgatgg tgaattgcca gatgagatga tggacttcta cgaagaccta gcagatctca
     2581 acttgaatgg caaaatctac ggagtggtcg gctcaggaga taccttctac gatgaattct
     2641 gtaaggctgt tgatgacttt gaccgtgtct ttgtgtcaac aggagcagaa aaaggttcag
     2701 agtgtgttaa agttgatctt tctgccgagg aagaagatat tgaacgcttg gaacaattcg
     2761 cagaagaatt ggctgctaaa gtaggataag cataaaagtg cgctgatgta atcaatcagt
     2821 gcatttttct tatcgagagt tgggatttta ctagcctaat tgatggcttt ttgatacaat
     2881 aattcaaata aaggaggaga ctgtatggat ttagatatta ttcgtcaaga aatcgatcaa
     2941 atcgacgacc aaattgtcaa actgttagaa gaacgaatgc atttagttga gggggtggtt
     3001 gcttataaga aagcttcagg taaaccgatt ttagatacta agagagaaga agttattttt
     3061 gaaaaggtta ggagtcgtgt agaggacaag cgctatcagg agactattgt agcgactttt
     3121 tcggacatac tcaaacgttc gcgtgattat caggatcaaa atatcaaatg aaaaaagaac
     3181 aattttatcc gctaggaatt tttctagctg ctatgttggg cggacttgtc cgatatctag
     3241 tttccacctg gttaccagcc agtccagact ttccttgggg cactctcttt gtcaactatc
     3301 tgggaatttt ctgcttgatt tttcttgtca agggctatct ggtctataag gggactagta
     3361 agggcttgat tttagcactg gggacgggtt tttgcggagg tttaacaacc ttttctagtc
     3421 tcatgcttga tgctgtgaaa ttactggata cagggcgtta tcttagtttg atactgtatt
     3481 tgcttttgag tatcggtgga ggcctgcttt tagcttacta tttggggagg aagaaatggt
     3541 aatcgtctat cttgcaatcg cctgtggctt gggagcactc gtacggtatt tcttttcccg
     3601 ctacaatcaa gcttctaaat tgccacttgg aacgctcata gctaatcttt taggttgttt
     3661 tttaattgga gtattctaca atcatgtaga gtctaaggaa gtatatgcta ttctagcaac
     3721 aggattttgt ggcggtttaa caactttttc gaccttgaat gacgaacttc aaagactgct
     3781 aagtgataag aaggtctttt attcttacct gactttgact tacataggtg gtttggttgc
     3841 gattttttta ggaattttgc tataaatttc tttacttttt tgtgaaaatt tggtagactg
     3901 tatcttgtgt gtgatggacg cacaaaaata cagtttatcc gctgaggaag tttcctcaag
     3961 attgacaaag ataggagaat aaaatgaatc cattaatcca aagcttgact gaaggtcaac
     4021 ttcgtacaga tatcccatca ttccgtcctg gtgacactgt tcgtgtacac gcgaaagttg
     4081 tcgaaggtaa ccgtgaacgt atccagattt ttgaaggtgt tgttatcgca cgtaaaggtg
     4141 ctggaatctc agaaaactac acagttcgta aaatctctaa cggtgtaggt gttgagcgta
     4201 tcttcccaat ccacactcca cgtgttgaaa aaatcgaagt tgttcgttac ggtaaagtac
     4261 gtcgtgcgaa attgtactac ttgcgtgctc ttcaaggtaa agcagctcgt atcaaagaaa
     4321 tccgtcgtta attcgactaa aaaactctgc ttttcagcag agtttttatc tagctccctt
     4381 agttcaatgg atataacaac tccctcctaa ggagtagttg caggttcgat tcctgcaggg
     4441 ggcagtaatt agacatcaaa aaccgctcag ctgagcggtt tttatctatt ctttcctttt
     4501 acagtaccca tgtacgaata gcatgggcaa cgccggattc gtcatttgtt ttggtggtgt
     4561 atttggcgat ttttttgatt tctggatttc cgttttccat gactacaggg ttgccaacga
     4621 cttccagcat ggcacggtca ttttcttcgt ctccgatagc catggtttca tctttggtta
     4681 atcctagttt ttcagctaag tgagtaatag ctgaaccctt gtctacattc tttttaagga
     4741 gttcgaggta gaaaggagca gatttgttga tagagtagtg ctcgtaaaat tcggctggta
     4801 ttttttcaat cgcagcatcg aggatttctg gttcatcgat gaacatacac ttgacaattt
     4861 ccttgccagc catttcttca ggagtgcggt agaagatagg catgctgacg agggttgatt
     4921 cgtgcacagt gtatgttccg atattgcgat tggcggtata gataccgtcc ttagtaatag
     4981 catgcatgtg aacaccaagc ttgcgactga gaaattccat atccagataa tcctcatagg
     5041 tcaaggattc gctgataatc tcatggccag tatcagtctc ttggacaagg gcaccattga
     5101 aggtcaccac atagtcacct tggtctctca actgcaagtc gtccagaagt ttggcaacac
     5161 ctgcgatggg gcggccagtt gcaatcacga ctttgacacc agcttctttg gcatcttgga
     5221 tggcagaaaa gacttcagga gtgatttcct tttggctgtt gactagggtt ccgtcaatat
     5281 cgacggcaat tagtttaata ctcataaaat tcctcttcta gtttttattt ggggtaaaat
     5341 gatcgttctc aatcaagtgt aaaaattgct gggtaatgct tgcaaagatg ctgttttggt
     5401 ccaacatttc ttttggaaaa taaaagcgat tatctccgtg gcgactgcca gcaagggatt
     5461 ggacgatagg agacaggcta gagagttcgg ccagttctcc atttttttgt aaaatctcaa
     5521 tctgtgtccg tgggttttca gattcgggac gatagatatc ataagggagg tcaaagttct
     5581 tatgaatggc agtgtagtag tcgggatcaa agccgatatc ctcaaccaat tttctcatgc
     5641 tagtaagttg atcttggtcc tcttgtgaaa aggtaatgga tttaaagacc ttgcggttga
     5701 caaagcgatg cgataaatct gcaagaatct tgtcaggact ggtcatccaa agctggaagt
     5761 aggtattcat cacgccatca tccagagcca gatagtcagt caaggtcaca tttttttcga
     5821 agaaaggcag gaggtgtgga gaagttcggg caaagaaatc cttgtcctca ggatagagtt
     5881 ccttggcgcg tttgagaaga ttctgtagga gaacttccat ggcgcgtgtt gcggggtgga
     5941 aataaacctg catgtacatc tggtagcgac tgaggacgta gtcttcgatg gcgtgcatgc
     6001 cattgcactg aaaggcgata ccattttcga taggacgaat gactcggagg attcgagtca
     6061 ggtcaaattc cccataggat gctcctgtaa aataggagtc acgcaagaga tagtccatgc
     6121 ggtccgcatc aatctggcta gaaatgagct gcacgacctg cttattagga taggtatggt
     6181 caatgacact ggccaccttt tctgggaaat caggtgccac ttgtagcagg acttggtgaa
     6241 tctctgtctc aggattttga ataatctcct gagtaatggc ttcatggtct gtatcaaaga
     6301 gattttcaaa agtatgggag taggcgccat gcccaaggtc gtgtaggaga gcagcggtca
     6361 tggtcaagag agactcggca ggattccatt cctcaggata tttttcttcg aaaatctctg
     6421 tgatgcgtcg tgcaatttca tagactccta gacagtgaga gaagcgactg tgttctccac
     6481 cgtggaaggt ataactggaa gttcccagtt gtttgatccg gcgcaaacgc tgaaattctt
     6541 ttgtattaat caagtcatag atgatttgat tattgacatg gatgtagttg tgaactgggt
     6601 cacggaatac tttttcgttc atatgaccat tatagcaaaa tcctgctctt tttggtaaaa
     6661 tagtaggaca agagacaaga aagaggactt gatgtgaaga ttcggatgcg aaatacgatt
     6721 cagtttgatg agcagttgga agtgattgac cagctttatg atgtggaagt gcatgaaaag
     6781 ggagattata gctatttact cttttataat gaggaaaagg aaaaagtagt tattaaattt
     6841 catggtcaag aactggtgat gagccgattt tctaatccca agaccattat gcgcttttta
     6901 aaggatagtg atagtttggc ctatattcct acccctatgg gcatgcagga atttatcatt
     6961 caaacgagcc gttatcaagt tgataggcaa aagattgagc tagcttatca actacaaaat
     7021 caagaggggc atccctttgc cagctatcaa ttggaaatta cttggggcta ggatctcgtt
     7081 tttctcaaat ctactttcta tcttcaagga ttggctccct agtgtggtag attaggctat
     7141 tttttggtat aataaaagtt atggaaatcg aaaaaaccaa tcgtatgaat gcgctctttg
     7201 aattttatgc ggcgcttttg acagataagc aaatgaatta tatagagctt tactacgctg
     7261 atgattacag tcttgctgag atagctgagg agtttggtgt tagtcgtcag gctgtctatg
     7321 acaatatcaa gcgaacagaa aagattctgg aagattatga gatgaaattg cacatgtact
     7381 cggactacat tgtccgtagt cagatttttg accaaatctt ggatcgctat cccaaggatg
     7441 attttctgca ggagcagata gaaattttaa caagcattga taatagagaa taagaggaag
     7501 aaaaatggca tttgaaagtt taacagaacg tttgcagaac gtctttaaaa atctacgtaa
     7561 aaaaggaaaa atctctgaat ctgatgtcca agaggcaacc aaagaaattc gcttggcctt
     7621 gctcgaggcc gacgttgcct tgcctgttgt aaaggacttt atcaagaaag ttcgtgagcg
     7681 tgcagtcggg catgaggtca ttgatacact taatcctgcg caacagatta ttaaaatcgt
     7741 tgatgaggaa ctgacagccg ttttaggttc tgatacggca gaaattatca agtcacctaa
     7801 gattccaacc atcatcatga tggttggttt acaaggggct ggtaaaacaa cctttgctgg
     7861 taaattggcc aacaaactca agaaagaaga aaatgctcgt cctttgatga ttgcggcgga
     7921 tatttatcgt ccagctgcca ttgaccagct taagaccttg ggacaacaga ttgatgtgcc
     7981 tgtctttgca cttggaacag aagtaccagc tgttgagatt gtacgtcaag gtttggagca
     8041 agcccaaact aatcataacg actatgtctt gattgatact gcgggtcgtt tgcagattga
     8101 tgagctcctc atgaatgagc ttcgtgatgt gaaagtattg gctcaaccaa atgaaatctt
     8161 gcttgtcgtt gatgctatga ttggtcagga agcagccaat gttgcgcgtg agtttaatgc
     8221 tcagttggaa gtgactgggg tcatccttac caagattgat ggtgatactc gtggtggtgc
     8281 tgctctgtct gttcgtcaca tcactggaaa accaatcaag ttcactggta caggtgaaaa
     8341 aattacagat atcgaaacct tccacccaga ccgtatgtct agccgtatcc ttggcatggg
     8401 ggatatgctc actttgattg agaaagcttc tcaggaatac gatgaacaaa aagcccttga
     8461 aatggctgag aagatgcgcg aaaacacctt tgattttaat gatttcatcg atcaattaga
     8521 tcaggtgcaa aatatggggc cgatggaaga cttgctcaag atgattccag gtatggccaa
     8581 caatccagca cttcaaaaca tgaaggtgga tgaacgccag attgctcgta aacgtgccat
     8641 tgtgtcttcg atgacatctg aagaacgtga aaacccagat ttgttaaatc caagccgtcg
     8701 ccgtcgtatt gctgctggtt ctggaaatac attcgtcgaa gtcaataaat tcatcaagga
     8761 ctttaaccag gctaaacagc tcatgcaggg tgttatgtct ggggatatga ataaaatgat
     8821 gaagcaaatg gggattaatc caaataacct tcctaaaaat atgccaaata tgggaggaat
     8881 ggatatgtct gcccttgaag gaatgatggg acaaggcggt atgcctgact tatcagctct
     8941 cggaggagca ggaatgccag atatgagcca gatgtttggt ggcggtttga aaggtaaaat
     9001 tggtgaattt gccatgaaac agtccatgaa acgtatggct aacaaaatga agaaagcgaa
     9061 gaagaaacgc aagtaagaca agagattgat gcaaatctca tttgatgaga aaataaagta
     9121 aaaatttcta tgataaaacg tacagtatca aggttttaga atatctgata ttatacgttt
     9181 tttgatttta ataattttgt taagacactt ttattatggt atacgaaaaa tccactcagc
     9241 tgtctgagtg gattaggtgt atttagactc ttagtcttta ttttcgtatg gcaagatcaa
     9301 gttcaagatg attcctgtca tggctgaaag ggcagtacct gaaagtgtaa ctggaccaag
     9361 tttaaggata gctcctccaa gtccaagaac caacatagca cttgcgatga tgaggtttcg
     9421 catttgagcg aaatcaacac gttctttaat caagactttc aaaccattgc tggcgataac
     9481 cccatagaga aggattgaca taccaccaag tacagcgttt ggaatagttg aaatcaaggc
     9541 agtgaattta ccaaggaagc tgagggcaat cgcgatgaag gcagcgttac ggataactga
     9601 gacagaagcg atacgagtca taccgataac ccctgtattt tctccgtaag ttgtattggc
     9661 tggtccacca aggaaggcag aaacagaagt tgcgataccg tcaccaataa gagtacggtg
     9721 aagacctggt tcttttaaga attgacggcc acagatttga cccaaaacag tatggtctcc
     9781 gatatgttca gaaattgtta cgatagcgat tggcaagata gcgatggctt ctggaccaaa
     9841 gtaaagattg tactctttaa aggcaccacc tgtgctaaat ggcaagtaga aaccaggaat
     9901 ttcgaaccag ttggctttaa gaactggtgt aaagtcaacc aagccaagag ttagtgcgaa
     9961 aaggtaacca ccgataatgg caaagaggaa tggaatgatt cgtaggaagc cttttccttt
    10021 tgtattgata aaggcagcaa ttaggaaagt aacaacggct accagagcat ttttccaatt
    10081 tccgtctgct acaagacctg cattggtaac agctgaacct gcaagtccaa gaccgataac
    10141 gatgatcata ggaccgataa tgattggtgg caagagttta tcaatccatt ttgttcctac
    10201 aaatcggatg ctggtagcaa caaggacata gaccaaacca gtcaagataa cccctgtttg
    10261 ggcagcagat acatcccccc ccatttcttt catagccagt gacatagctg tgataaaggc
    10321 aaatgaagaa cctagataaa ctggaacttt aaaaccagta gcaatcatgt agatgagtgt
    10381 tccaacacct gaagcaaaga gggcaacaga tacaggcatt cccaaaatca atggtaccaa
    10441 gatggtcgca ccaaacatgg cgaaaacgtg ttggaagcta aggagaattc cttttccatc
    10501 cgaaggacgt tggtcaacgt ctagtaacaa atcaacagtt gattcttgtt tcatataaac
    10561 ctcacttttg ggcatcagaa aagagcccat tattttacag caataggccc tcagagtaag
    10621 acttctctaa aatctagact ttaaagagtt tcaaatattt ttgcgtcttc gtcacctcac
    10681 gggatgacat taaaaacctt tgcttaggat agtatagcag aaaaaaatga ttttgtaaat
    10741 cattttttcc cgagcctaga aataaaagag cgaggctgat tttgtaaaca tttgtttact
    10801 aaaaaattta aagtgggcgt ttatttggca taccagcctt acgtggatat ttatttggtg
    10861 tttctttttt cttttctacc actgtgatat agcgcggatc tctattcggt agggcgtagc
    10921 tgagattgtc ttcgacctta ctaaaaagga gattgagggc attcttagct tctaataatt
    10981 cctcaggcgc attgctggcc ttgagtgcca atagtttgcc accaacctta aggtagggaa
    11041 tagtcaattc agataggacc tgcatacggg caaccgcacg agctgttaca aaatcatatt
    11101 gagcacggaa gttcttgtct tgggcaaaat cttcggcacg tccgtggtag aaatgaactc
    11161 cgttcaaatc cagttcttga gccaagagtt gtaggaagtt gatgcgctta ttgagtgaat
    11221 caataatggt cacatctaac tccggataga gaattttcat tggtagacta ggaaatcctg
    11281 ccccagcccc gatatcaaga agtttgatag tttcattggg aatcaaacct tgaagaatgg
    11341 gtgcaatcga atcgtaaaaa tgtttgagat aaacttcttc cttgtccgta atcgccgtca
    11401 aattaatctt ctcattccac tcgaccaaga gctcaaaata acgttcaaat tgttcttttt
    11461 gctggttcga aagtggaaga ttttgctcgg caagcaagtt gtaaaatgtt tctggtttca
    11521 tagttatttc cttctttagt atcatcttat tttaccacaa tcattaaaaa tttgatatac
    11581 tggtactaat ctaaaagtag aaaggactta tatcatgact tggattattc ttggagttat
    11641 cgctcttatt gttgtttttg tgattgttag ctataacggt ttggttaaaa atcgtatgca
    11701 aaccaaggag gcttggagtc agattgatgt tcagttgaaa cgtcgaaatg acctcttgcc
    11761 aaacttgatt gagactgtaa aaggttatgc caaatatgaa ggttctaccc ttgaaaaggt
    11821 ggcagaacta cgtaaccaag tggcggcagc gacttcacca gcagaagcta tgaaagccag
    11881 tgatgccctc actcgtcagg tttcaggtat ttttgcagtt gcagaaagct atccagattt
    11941 gaaagctagt gctaactttg ttaaattgca agaggagttg acaaatacag aaaataaaat
    12001 ttcttactct cgtcaactct ataacagtgt tgtcagcaac tacaatgtaa aattagaaac
    12061 tttcccgagc aatattatcg ctggaatgtt tggatttaaa gcggcagatt tccttcaaac
    12121 acctgaagag gaaaagtcgg ttcctaaagt tgattttagc ggtttaggtg actaagatgt
    12181 tgtttgatca aattgcaagc aataaacgaa aaacctggat tttgttgctg gtatttttcc
    12241 tactcttagc tcttgttggt tatgcggttg gttatctctt tataagatct ggacttggtg
    12301 gtttggttat cgcactgatt atcggcttta tctacgcttt gtctatgatt tttcaatcga
    12361 cagagattgt catgtccatg aatggagcgc gtgaggtgga tgagcaaacg gcaccagacc
    12421 tctaccatgt agtggaagat atggctctgg tcgctcagat tcctatgccc cgtattttca
    12481 tcattgatga tccagcctta aatgcctttg cgacaggttc taatcctcaa aatgcggctg
    12541 ttgctgcgac ttcaggtcta ctagctatca tgaatcgtga agaactagaa gctgttatgg
    12601 gacatgaagt cagtcatatt cgtaattatg atatccgtat ttcgactatt gcagttgccc
    12661 ttgctagtgc tatcaccatg ctttctagta tggcaggtcg tatgatgtgg tggggtggag
    12721 caggtcgcag acgaagtgat gatgaccgag atggaaatgg tcttgaaatc attatgctag
    12781 tggtttccct actagctatt gtactggcac ctctcgctgc aaccttggtt cagctcgcta
    12841 tttctcgtca gagggaattt ctggcagatg catctagtgt cgagctgact cgcaatcccc
    12901 agggaatgat taatgcccta gataagttgg acaatagcaa acctatgagt cgccacgtcg
    12961 atgatgctag cagtgccctt tatatcaatg ctcccaagaa aggtgggggg gtccaaaaac
    13021 tcttttatac ccacccacct atctcagaac ggattgaacg tttaaaacag atgtaaaatg
    13081 aaggctggaa aaaagtcttt aaaatctgaa aaatgcataa tatcaggtgt gaaaacttga
    13141 tattatgcgt tttactatgg gaagatttac ttctttttct cctaaaattg tgtttttgcc
    13201 ccacctatct gctatgttgc aaatttataa atcttctaaa ttaactagct tcaaaccgtg
    13261 ttctgtcatg cgacagatga tcgagcagac ttcttttaag aaacgacggt catgcgaaac
    13321 agtgatgaga ccgcctggat aggttgcaaa gagttttctg atttggggtt gagaagtggg
    13381 agaaaagttt cgtgtgggtt catccagcag gagaaagttt ggtttgcgca ggactagatc
    13441 caaaagcagg agttttccct gttgtccgcc agataaggag cgaatttgat gctgcatttc
    13501 tggataactg aaattgagac tggctaggtg agattgaatt ttctgaagtt cctctttttc
    13561 cccagttttg ctgatataag ctattggtga taaatccaat tgtagttttt tgtggtaatc
    13621 ttgtggcata aaaccaaggg aaatctctct tttatcattc agaagttgct ttaatttggc
    13681 taacagagtt gatttcccaa caccatttgg cccgataata ccgatttttt cttgcccacg
    13741 gacagttagt tgtagttttt gaaccaaaac tcggtcgtca atggacaaat tttctttttc
    13801 cagttggact aagactttag aagctggtaa tggttggata tctgaaaaga aaagttggat
    13861 ttgttcctct tcaagtggtt tttgagtcat ggactgagct gccttttcgt agcgtttttc
    13921 ttgtgagagg acagttttca tctttttagc caataggcga ccggcagtac tatctttggt
    13981 agctcgaagc gcagtttcta cattttgctt aactctccga tgtttttcca tggttttatc
    14041 gtaggctctt tggttgttag cagcttgctg actttgtttg gcaaaattag cctttctctg
    14101 ctcactatag ctatcatagt ctaaatgctc tactagcgtt tccgcttctt tacggtgttt
    14161 gaccagtcgc aagtgaacaa tagtgtctgc cgtttcagaa agaaagtctt catcatggga
    14221 aatgaaaata acggtttgcc tggtcttttg aatctggcct tttagccaat caactgtctc
    14281 aaggtctagg tcatttgaag gttcatctaa aaatagaatc tcaaagggtt tggctaactc
    14341 atggataagc tgaattttca aagcttctcc ccctgataga ttgccaatct cttggtcact
    14401 tgcgaaacga ttgctatcaa aatgcaattc ctccgccaaa cgatagagga tactgtagtc
    14461 taaatcaata gaatctaaaa agaagtagtc gtgtaaagtt ttctttttca gctcctcggg
    14521 aagtttttga ggaatgtagg ccagtgactg atagtcagat tggatgtttc ccttgatagt
    14581 gaaatcagac aaagcttccc ccattaaaat tttaagtaag gttgatttgc catttccttc
    14641 ttcaccaata atagcaacct tttccccgtc ttggatggtc atgcttaggt cagatacaag
    14701 atctcgtaaa tctttgtttt gtgtgatggt tagatgattg atttttatca tatgatttcc
    14761 ctttctagaa tgttcatagt gcataacaaa aagctctact ttacctagta gagcccaaag
    14821 tctatgtcaa aaaaactcta ttaacatgcc agaaaaagag cataaaagag cacacaaaaa
    14881 gagacaaaaa caagatctac taaataaagg ttctttattt gatagactta gttgttcatg
    14941 tctcccttac ctccgagtat tagtatcttt atattatacc tttaaggaaa ttttgtcaac
    15001 agaaaactgg aaattctatg ctctaaaatt caaaaacagg tctatagaga cttagtacgt
    15061 gtttgacatg ctcgtaatgg aatttatcat agtttcgcca agcagtgcgt gcttgatcgt
    15121 ttagttttag gctacccagt ccaatcagaa gactggtggg ttggtaaaat ttctcaagat
    15181 caattaagat actgttgttc aactgttccg tttttttgag ctcttgcata gtagtgttta
    15241 gcagctcttg tagtcgaata tcatctgccg taccctgttt acagttttgg tagcttttat
    15301 ttaacttgga taggagttga atgagtttct tgtcttccat gtgagcatcc tccttgatct
    15361 gatgtactct ttccctatag tatagcacta aaaaacaaaa ctgtcatagt aaatatgtta
    15421 aagttttgaa ttttaattac aaagtttggt gtgctgattt gtagcctttt catggtataa
    15481 tcaagagagt aaatctttat ggaggaagta tgaaattaaa tattcaagaa attcgtaagc
    15541 agtctgaagg tttgaacttt gaacaaacgt tagatttagt tgatgacctg cgtgcacgta
    15601 atcaagaaat tttagatgta aaagatatcc ttgcagttgg gaaagtacaa tatgaagacc
    15661 gtatgtattt cttagattat caactatctt ataccattgt tcttgcttcg agtcgcagta
    15721 tggagccagt tgagttagtt gaatcttatc cagtcacgga agttttcatg gaaggcgcaa
    15781 ctaaccagct agatcaagaa gttttagatg atgacttggt cttgcccatc gaaaatgggg
    15841 agcttgacct tgctgagagt gtatcagaca atatcctgct aaacattcct atcaaggtct
    15901 tgacggctga agaagaagct ggtcaaggat ttatctcagg aaatgactgg caaatcatga
    15961 cagaggaaga ataccaagct caaaaagcag taaagaaaga agaaaacagt ccttttgctg
    16021 gcttacaagg actatttgac ggagatgaat aatgatcttg tcaaaaaaac gagcacgaaa
    16081 ggtgctagaa gaaatcattg ccctcttccc agatgccaag cctagtcttg attttaccaa
    16141 tcattttgaa ctcctggttg cggtcatgtt atcagcccag acgacagatg cagcggtaaa
    16201 taaggccaca ccaggtctct ttgttgtctt tccaacaccc caagctatgt ctgtagcgac
    16261 agagagtgag attgcttcac atatttctcg cttgggattg tatcggaata aagctaaatt
    16321 ccttaaaaaa tgtgcccaac agttactaga cgattttgat ggtcaagtcc ctcagacacg
    16381 tgaagaattg gagagtttgg caggtgttgg tcgcaagaca gccaatgttg tcatgagtgt
    16441 aggatttggg attccagcct ttgcagtgga tactcatgtg gagcgtattt gcaaacacca
    16501 cgatattgtc aaaaaatcag cgacgccact tgaggtggaa aagcgggtca tggatatctt
    16561 gccgcctgag cagtggttag ctgcccatca ggccatgatt tattttggaa gagccatttg
    16621 ccatccaaaa aatccagagt gtgaccagta cccacaatta tatgatttta gcaatttgta
    16681 agatgctaca ttgaaacttt ttgcttgatt ttaagcatgc tttgtgctat agtaaatgat
    16741 aactaaatat tcctttaaac ctgtcccgtg aggcaggcaa ggagcgcgat aaagtagaag
    16801 ggtgaagtct atactgtgtg cagtagggct cgcttggcta taaatttcaa gtctccttgt
    16861 ttaaggagac ttttcttttt ggaggtttgt catgaaaaca aaagaagttg tagacgaatt
    16921 gaccgtcaaa cgagcgatta cgcgtattac ttatgagatt atcgaacgca acaaagattt
    16981 gaataagatc gtcttggctg gtattaaaac tcgtggtgtc tttattgccc accgaatcca
    17041 agaacgtttg aagcagttag aaaatctttc agttcctgtt gtggaattgg atactaaacc
    17101 tttccgtgat gatgttaaaa gtggagaaga tacttctttg gtttctgtcg atgtgacaga
    17161 ccgcgaagtt atcttggtgg atgatgtgct ctatacaggt cgtaccatcc gtgctgctat
    17221 tgataatatt gtcggtcatg gtcgtcctgc gcgtgtgagt ttagcagttc tagtcgatcg
    17281 tggacataga gaattgccaa tccgtccaga ttacgttgga aaaaatatcc caaccagtcg
    17341 ttctgaagaa atcatcgtag agatgacaga acttgatgac caagacagag ttctgattac
    17401 tgaagaagct tagaaagtta aaggagtagc catgtcagaa aatcaacaag cattgaacca
    17461 tgtggtgtcc atggaagacc tcactgttga tcaagtaatg aaattgatca agcgaggaat
    17521 tgagtttaaa aatggagccc agattcccta tgaagaccat ccgattgttt ccaatctctt
    17581 ctttgaggat tctacacgga cacataagtc ctttgaagtc gcagagatta aacttggatt
    17641 ggaacgactt gactttgatg tgaagactag ttcggttaat aagggtgaga cactttatga
    17701 caccattttg actctgtctg ctttaggagt ggatgtctgt gtgattcgcc atccagaggt
    17761 cgactactat agagaattga ttgctagtcc aacgattacg acttccatca tcaatggtgg
    17821 agatggttct ggccaacacc ctagccagag cttgcttgat ttgatgacca tttatgagga
    17881 atttggccac tttgagggtc ttaaagttgc tattgcaggt gacttggacc actcacgcgt
    17941 tgccaaatcc aatatgcaga ttttgaaacg cttgggagct gaactctttt tctctggacc
    18001 tgaggaatgg agaagtcaag agtttgcaga ctatggacag tttgtaacca ttgatgaaat
    18061 cattgatcag gttgatgtca tgatgtttct ccgtgtgcaa cacgaacgcc atgatagtgg
    18121 agctgtattt tcaaaagaag actaccatgc ccaacatggc ttgactcaag aacgttacga
    18181 tcgtttgaaa gaaacagcaa tcctcatgca cccagctcca atcaatcgtg atgtagaaat
    18241 agcagaccac ttggttgaag caccaaaatc acggattgtc caacaaatga ccaatggtgt
    18301 ctttgttcga atggcaatct tagaatccgt actagcgagt agaaacgcca actaaaacac
    18361 aagacgttaa aagacgccag tgagcgtcca cgagaggtga aaatatgaca aaaagaattc
    18421 tagtattaga agatggcaca gtttttgaag gcaaggcctt cggagcagat attgatgtaa
    18481 caggcgaaat cgtctttaat acagggatga ccggctacca agaatccatt acagaccagt
    18541 cttataatgg acaaatcttg acctttactt atcctttggt aggaaattat ggtattaatc
    18601 gtgatgatta tgaatccatt attccaactt gtaagggagt cgttgttttt gaagaagcgc
    18661 gtagagctag caactggcgc aaccaaatga ccttggatga atttttgaaa gccaagaaaa
    18721 ttccagggat ttcaggaatt gatacgcgtg ctcttaccaa gattatccgt aagcatggta
    18781 ctatgcgtgc aaccttgacc catgttgggg acagtatgga ccatgtgacg gaccagctcc
    18841 aagcaacagt tttaccgaca gacaatatca aacaggtttc tactaaaacg tcttatccag
    18901 ctccaggagt tggtttgagc gtggtgctag tggactttgg tctcaagcac tcaatcctac
    18961 gtgaactttc taaacgcaac tgtaacgtga cagttgttcc ttattcgaca acggctgaag
    19021 aaattctcca tctcaatcct gacggagtta tgttgtcaaa tggtccaggt aacccagaag
    19081 acgttccaca agcactcgac atgattcgcg gtgtacaagg aaaaattcca atctttggta
    19141 tttgtatggg acaccaactc tttgcaatgg caaacggggc taagacctat aagatgaagt
    19201 ttggccaccg tggattcaac catgcggtac gtgaaatcgc aacaggacga gtagacttca
    19261 ccagccagaa ccatggttat gcagtcagcc gcgaggattt gccagagcac ttgattatta
    19321 cccacgaaga aatcaatgac aagtcagtgg aaggtgtgcg ccacagatac caacctgctt
    19381 tctctgttca ataccaccca gatgcagctc ctgggccaca cgacgctagc tacttatttg
    19441 acgagtttat cgagatgatg gaagttttta aacaatcaaa ctaagaacga gtaaaagctc
    19501 gtcggagaat ttatgtaact gaacacggac ggaaagctca gaatttagag aaaccaactt
    19561 ggattgtcaa tccttccttg atttcctaaa aatcaatcgc tttctattcg tcctttgtat
    19621 cttatttaat gtcgccctga gaggctacga atagaaagga gaagggtgct ccgtatttgc
    19681 tgaactgaat acgggctacg gacggtgcta aaaagatagt tattcctaga actgacagtt
    19741 cttcgtcata actcctattt tagctttgtc cgcttgacgc ccttaatatc ttatatatgc
    19801 ctaaacgtac tgatattcaa aaaattatgg tgattggttc tggtccgatt attattggtc
    19861 aggctgctga gtttgactac gctgggaccc aggcttgctt gtcgttgaaa gaggaaggtt
    19921 atgaggttgt tttggttaac tcaaatcctg caaccatcat gacggacaag gaaattgctg
    19981 ataaggttta cattgaaccg attacacttg agtttgtgac acgtattctt cgtaaggaac
    20041 gtccagatgc cttgctacca acactcggtg gtcagacagg tctcaacatg gccatggaat
    20101 tgtctaaaaa tggtatctta gatgagctta gcgttgaact tctgggtact aaattgtctg
    20161 ccattgacca agcggaggac cgtgacctct ttaaacaatt gatggaagag cttgagcaac
    20221 ccattccaga atctgaaatt gttaacacag tagaagaagc agttgccttt gcagcgacaa
    20281 ttggctaccc agtcatcgtt cgtccagcct ttacccttgg tggtactggt ggtggtatgt
    20341 gtgccaacga gaaagaattg cgtgaaatca ctgaaaatgg tttgaaattg tcacctgtta
    20401 cccaatgttt gattgagcgt tcgattgccg gtttcaagga aattgaatac gaagtgatgc
    20461 gtgactcagc tgacaatgcc ttggttgttt gtaacatgga aaactttgac ccagttggga
    20521 ttcacacagg ggattccatt gtatttgccc ctgcgcaaac catgtcagac tatgaaaacc
    20581 aaatgcttcg tgatgcgagc ttgagcatta ttcgtgccct caagattgaa ggtggatgta
    20641 atgttcagct agctcttgat cctaacagct tcaagtatta tgttatcgaa gtaaaccctc
    20701 gtgtatcacg ttcgtcagcc cttgcttcta aagcgacagg atatccgatt gctaagttgg
    20761 ctgccaagat tgcagtaggt ttgaccttgg atgaggttat aaacccagtt acaggttcaa
    20821 cctatgccat gtttgaacca gcccttgact acgtagttgc taagattcca cgtttcccat
    20881 ttgacaagtt tgaaaagggt gaacgccgtc tcggtacaca aatgaaggcg actggagaag
    20941 tcatggcaat cggtcgtaac atcgaggaat ctcttctcaa ggcctgccgc tcccttgaaa
    21001 ttggggtgca ccacaatgaa atacctgaac ttgcagtagt ttctgatgat gccttgattg
    21061 aaaaggttgt caaagcccaa gatgaccgtc tcttctacgt atcagaagca attcgtcgtg
    21121 gctacacacc tgaagaaatt gcagagctta caaaaattga tatcttctat cttgataaac
    21181 tcttgcatat ctttgaaatt gagcaagaat tgggtgctca tccacaagat ctagaagttt
    21241 tgaaaacagc caaacttaat ggtttttcag accgtaagat tgctgaactc tggggaacga
    21301 ctgatgataa agttcgccaa cttcgcttgg aaaacaagat tgttccagtt tataagatgg
    21361 tagacacatg tgcggcagag ttcgactccg aaacgccata tttctattca acctatggtt
    21421 gggaaaatga atctatcaga tctgataaag aatctgtact tgtcctaggt tcaggtccaa
    21481 tccgtatcgg tcaaggggtt gagtttgact acgcaaccgt tcactctgtt aaggctatcc
    21541 aggcagctgg ttatgaagct atcatcatga actcaaaccc agagaccgtt tcaacagact
    21601 tctctgtatc agataagctt tactttgagc cattgacatt cgaagatgtt atgaacgtca
    21661 ttgacttgga acaaccaaag ggagttatcg ttcagttcgg tggtcaaaca gccatcaacc
    21721 ttgcggagcc attggcaaaa gcaggtgtga ccatccttgg tacacaggtt gctgacctag
    21781 accgtgccga agaccgtgac ctcttcgagc aagctctcaa agaattggat attccacagc
    21841 caccaggaca aacggctacc aatgaagaag aagcagctct tgcagctcgt aagattggct
    21901 tcccagttct tgtccgccca tcttatgtac ttggtggacg tgccatggaa atcgttgaaa
    21961 acgaagaaga tcttcgttct tacatgcgaa ctgctgttaa ggctagtcca gaccacccag
    22021 ttcttgtcga ctcttatatc gttgggcaag agtgcgaagt tgatgccatt tcagatggta
    22081 aaaatgtact cattcctggt atcatggagc atatcgaacg tgctggtgtc cactcaggtg
    22141 actcaatggc tgtttaccca ccacaaacct tgtcgcaaaa ggttcaggag accatcgcag
    22201 actacaccaa acgcttagca atcggtcttc actgccttgg aatgatgaac atccagtttg
    22261 ttatcaagga tgaaaaagtc tacgttattg aggtcaatcc acgtgccagc cgtaccgttc
    22321 cattcctatc taaggtaacc aatattccta tggctcaagt agcgaccaag ctcattcttg
    22381 gtcaaagttt atcagaactt ggctaccaaa atggacttta ccctgaaagc acccgtgttc
    22441 atatcaaggc acctgtcttc tcctttacca aactagctaa ggtagacagc ttgctcggtc
    22501 ctgaaatgaa gtcaacaggt gaagttatgg gttctgatgc tactttggaa aaagctctct
    22561 ataaagcctt tgaagcttct tatctacact tgccaacttt tggtaatgtc gtctttacca
    22621 tcgctgatga tgccaaagaa gaagccttga acttggctcg tcgtttccaa aacattggtt
    22681 atggaatcct tgcgacagaa gggacagcag ccttctttgc tagtcatggc ttgcaagccc
    22741 aacctgttgg taagattggt gatgacgata aggatatccc aagttttgta cgcaaaggaa
    22801 gaattcaagc tatcattaac acagtaggaa caaaacgaac tgctgacgaa gatggtgagc
    22861 aaattcgtcg ttcagccatt gaacacgggg tgcccctctt cacagcgcta gatacagcta
    22921 atgccatgct taaggtactt gaaagtcgta gctttgttac agaagcgatt taaatataaa
    22981 aataagatat agcagactga atttagaaca gtacacaggg at
//
LOCUS       DAVKBC010000031        22078 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVKBC010000031 DAVKBC010000000
VERSION     DAVKBC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22078
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.031"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(1..156)
                     /locus_tag="VWX64_001423"
                     /pseudo
     CDS             complement(1..156)
                     /locus_tag="VWX64_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(540..1736)
                     /gene="tuf"
                     /locus_tag="VWX64_001424"
     CDS             complement(540..1736)
                     /gene="tuf"
                     /locus_tag="VWX64_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9190881.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2647..3516)
                     /locus_tag="VWX64_001425"
     CDS             complement(2647..3516)
                     /locus_tag="VWX64_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9190882.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYTATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3739..4260)
                     /locus_tag="VWX64_001426"
     CDS             complement(3739..4260)
                     /locus_tag="VWX64_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9190883.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(4218..5324)
                     /locus_tag="VWX64_001427"
     CDS             complement(4218..5324)
                     /locus_tag="VWX64_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU9190884.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVRVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5435..5689)
                     /locus_tag="VWX64_001428"
     CDS             complement(5435..5689)
                     /locus_tag="VWX64_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190885.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(6029..6562)
                     /locus_tag="VWX64_001429"
     CDS             complement(6029..6562)
                     /locus_tag="VWX64_001429"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU9190886.1"
                     /translation="MTSFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVGGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLERFFKTR"
     gene            complement(6549..6764)
                     /locus_tag="VWX64_001430"
     CDS             complement(6549..6764)
                     /locus_tag="VWX64_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9190887.1"
                     /translation="MGKERREQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(6731..6874)
                     /locus_tag="VWX64_001431"
     CDS             complement(6731..6874)
                     /locus_tag="VWX64_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEU9190888.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            7108..8826
                     /locus_tag="VWX64_001432"
     CDS             7108..8826
                     /locus_tag="VWX64_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU9190889.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIETPFAVEVADVETEKASGLIEVIGEVVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8937..9284
                     /locus_tag="VWX64_001433"
     CDS             8937..9284
                     /locus_tag="VWX64_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9190890.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGALSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9562..10398)
                     /locus_tag="VWX64_001434"
     CDS             complement(9562..10398)
                     /locus_tag="VWX64_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9190891.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10411..11040)
                     /locus_tag="VWX64_001435"
     CDS             complement(10411..11040)
                     /locus_tag="VWX64_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9190892.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAESYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11050..11691)
                     /locus_tag="VWX64_001436"
     CDS             complement(11050..11691)
                     /locus_tag="VWX64_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9190893.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11837..13066)
                     /locus_tag="VWX64_001437"
     CDS             complement(11837..13066)
                     /locus_tag="VWX64_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU9190894.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLNTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13056..14222)
                     /locus_tag="VWX64_001438"
     CDS             complement(13056..14222)
                     /locus_tag="VWX64_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9190895.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14366..15379
                     /locus_tag="VWX64_001439"
     CDS             14366..15379
                     /locus_tag="VWX64_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU9190896.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15424..15843)
                     /locus_tag="VWX64_001440"
     CDS             complement(15424..15843)
                     /locus_tag="VWX64_001440"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU9190897.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15854..17260)
                     /gene="atpD"
                     /locus_tag="VWX64_001441"
     CDS             complement(15854..17260)
                     /gene="atpD"
                     /locus_tag="VWX64_001441"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU9190898.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17346..18224)
                     /locus_tag="VWX64_001442"
     CDS             complement(17346..18224)
                     /locus_tag="VWX64_001442"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU9190899.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLSDQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18240..19745)
                     /locus_tag="VWX64_001443"
     CDS             complement(18240..19745)
                     /locus_tag="VWX64_001443"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU9190900.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19760..20296)
                     /locus_tag="VWX64_001444"
     CDS             complement(19760..20296)
                     /locus_tag="VWX64_001444"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU9190901.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20296..20790)
                     /gene="atpF"
                     /locus_tag="VWX64_001445"
     CDS             complement(20296..20790)
                     /gene="atpF"
                     /locus_tag="VWX64_001445"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU9190902.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20804..21520)
                     /gene="atpB"
                     /locus_tag="VWX64_001446"
     CDS             complement(20804..21520)
                     /gene="atpB"
                     /locus_tag="VWX64_001446"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU9190903.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21555..21755)
                     /locus_tag="VWX64_001447"
     CDS             complement(21555..21755)
                     /locus_tag="VWX64_001447"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU9190904.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(21830..>22078)
                     /locus_tag="VWX64_001448"
     CDS             complement(21830..>22078)
                     /locus_tag="VWX64_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9190905.1"
                     /translation="YYAHPYASWERGTNENHNRLIRRWLPKGTKKMTPKEVAFIEKWI
                     NNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
BASE COUNT         6574 a         4749 c         4020 g         6735 t
ORIGIN      
        1 ttgtttgatt acagtctaaa agttctataa tctctttata agatttgccc atatcagacg
       61 aaatagaacg atttgaagac gtttatgata tttagctgta cgagagtctt ttaaaagtgt
      121 tttgatggtt tggatttctt ctttaattga tttcatatta ctattgtata atgctttttg
      181 attttagtct agtattatac tcttcgaaaa tctcttcaaa ccgcgtcagc ttcgccttgt
      241 cgtatagatg ttactgactt cgtcagttct atctacaacc taaaaacagt gttttgagca
      301 gtctgtagct aactttctat agtaaaatga aataagaaca agacaaatcg atcaggacag
      361 tcaaatcgat ttctaacaat gttttagaag taaatgtgta ctattctagt ttcaatatat
      421 tatagtttgc tctttgattt tcattgagta ttagttcaat atctaaaaaa agaaccttgc
      481 caagcaagat tcttttagtg tctgacttaa ataattgttc ttctgggaac taaatcgaat
      541 taagcttcga tttctgtaac catacctgaa ccaacagtac gtccaccctc acggatagag
      601 aatgtagtac cttgttctac ggcgattggg tgaatcaact caacgtcgat tgtcacgtta
      661 tcaccaggca ttaccatttc agtacctgct ggaagttcga ttgaacctgt aacgtcagta
      721 gtacggaagt agaattgtgg acggtagttg ttgaagaatg gagtgtgacg tccaccttct
      781 tctttagtaa ggatgtagac ttcacctttg aatttagtgt gtgggttgat tgaacctggt
      841 ttagcgataa cttgtccacg ttcgatttca tcacgttgaa caccacgaag aaggacacct
      901 acgttatctc cagcaagacc ttcgtcaagt tgtttacgga acatttcaac accagtaaca
      961 actgcttttt gagtttcttc tttgatacca acgatttcga tttcgtcgtt gactttaacg
     1021 ataccacggt cgatacgtcc tgaagcaact gtaccacgtc cagtgattga gaatacgtcc
     1081 tcgactggaa gaagcaatgg tttgtcagtg tcacgttctg gttctgggat atactcatca
     1141 actgtgttca tcaattccat aacgatgtct tcgtatttag agtcaccttc aagagcttta
     1201 agtgctgaac cttggataac tggaagatcg tcacctggga agtcgtattc tgacaatagg
     1261 tcacggattt ccatttcaac caattcaagc aattcttcgt cgtcaaccaa gtcaactttg
     1321 ttcatgaaga cgataaggtg tttaacacca acctgacgtg aaagaaggat gtgctcacga
     1381 gtttgtggca ttggtccgtc agttgaagct actacaagga tagctccgtc catttgagca
     1441 gcaccagtga tcatgttttt aacgtagtcc gcgtgtcctg gagcgtcgat gtgagcgtag
     1501 tgacgttttt cagtttcgta ctcaacgtgc gcagtgttga tagtgatacc gcgttcgcgt
     1561 tcttctggag cagcatcgat agacgcatag tctttaggtt ggttaactga tgaaggcaag
     1621 cgacgtgcca aaacagttgt gatagctgca gttagggtag ttttcccgtg gtcaacgtgt
     1681 ccgatagtac caatgttaac gtgtggttta ctacgatcgt atttttcttt tgccatttga
     1741 gtaaaagcct ccaataaaat atattttata gatagacagt aggcaataca gtctaacttt
     1801 ccttactatt ttatcaaatt tcagctaaat tgcaagtgtt ttacaacgtt tttgtgaatt
     1861 attcttgata aaaatttaac taactaatag aaagtactaa atagacttat ccttcaagga
     1921 gttttcagca ttatccatcc actcacttgc tgaaaatgta aacagtctct ggtttatata
     1981 gtaaaatgaa acaagaatag ggcaaatcga tcaggacagt caaatcgatt tctaacaatg
     2041 ttttagaagt tgaggtgtac tattctagtt tcaatctact atacaacctc aaaactgtgt
     2101 tttgaacaac ctgcggctag cttcttagtt tgccctttga ttttcattga gtataaaatt
     2161 gcagataaaa cgataacaat cataggactc agcagagtca atgtaggtcg aagaatagcc
     2221 ctcctaatcg cttattttat agcaaaatga aatagaaact gaacattttg ttgaggaagg
     2281 taaatcaatt cctcacaatg tttgagaaag aagggaggac tattccaact tcaacccact
     2341 ataaagcaga cttacaagat agggaaccca tctccgataa tatatagtag aatgaaaact
     2401 gcacaatttg attggagaat tcaaaccaat ttctaacaat gttttagaaa caagggtcta
     2461 ttatttcaac tgcaacctac tatagcccat tgaagctgga atagcccact gagacttcta
     2521 aaccactgct ggagaggagt ttgtttagag tttctttcat ttccctaaaa aatcaaaaag
     2581 agagaaccag tctgatcctc tcttacttat agatggtgct cactcaaatg ttaaaggagc
     2641 tatttcttag agataaagga atttgaatac agctactgcc gcaattgctg ctgcgatagg
     2701 tgctactact ggtacccaag aataccacca ttttgaatcg cctttatgct caccaagaac
     2761 tgattttgga aggaaagcat gaaggagacg tggtcccaag tcacgggctg ggttcaaggc
     2821 aggtcctgta ggtcctccaa gtgatgttac caaagccata acgaggaatc caagtgccaa
     2881 gtgagccaca gaaagtcctg aagcagtgtg tggagccacc tgtgctttaa tagccaagtc
     2941 agaaaaatca actgtttgtc ctgcttctat tgccttttgt ttcatgaatt gaagcacttc
     3001 agcaccaaag aagtttttag tcaaaccaag agctgcaaag aacaaaacaa atgaaccaac
     3061 aaactcatta atcaaaccat tgacagttgc tgtatagcga ctttcttttg taccatggtc
     3121 aatacttgaa atagttgaga aagttcccaa gatgttattt ggtttttcag ttttcaagta
     3181 gaatggacgg tatgttgcca caactaaggc ttggccaaag atagccccca agacttgcgc
     3241 gataatgtaa ggtaccactt gtgcccaagg gaaaagaccg ctaactgcaa gccctagagt
     3301 gaaagcaggg ttgatgtgat tcccagatac gttaccaaac atcaaggctg ggatcataac
     3361 ccccatacca taaccaacag cgatgacgat ccagccactt tggtgacctt tcgtaccttt
     3421 aagttcaacg ttggcaactg caccattccc aagaatgatc aaaatggcag ttcccaaaaa
     3481 ttcagtggca tacttcagtg cccatgtgaa atccatttgc tagattctcc ttaaaatttt
     3541 ttagatattc cttattttat caatttttac cctatttagc aactgatttc tggaaatatt
     3601 tttaaaaaaa taggattcat agtttcccag ttcaacgtac ttgtaagcgt ttttattctt
     3661 cacgaaagac ctcattctca aaaccaggaa aaagcccaca tctgtgatct tttccttgtt
     3721 cctagattct aaaatctatt atttttcatc ttcttttttc ttgaagaatc ctaatcctag
     3781 accagctaac aaggtcatga taccagcact agccaaggta gcattagctt ctgtacctgt
     3841 gtttggcaat tcctctctct tacctgtctc ataagtcgga acttctgggt ctggattcac
     3901 tggagtttca gtttttggag tacctggttc tggagttggt ttatctggtg ttgataaacg
     3961 gtcatacctt accgttattt ctttatcact agagtctgac gtaacttctt gtgattcaac
     4021 tgttggaata tctggatctt tgtacttgtc aatcttacca gatataacct cgtcccagtt
     4081 tcctgttgtc cattcaccgt aggttacaac tcccgtgacc ttgttctcag tttttgtacg
     4141 gcttaaggtt acaggttgaa caacatcttc ttttacattt tggttcgtaa ctttatcaac
     4201 gtaatgaatg atacgcgtta tagtcttcgt ctcagtagag gttgctgttt tgggaaccac
     4261 tgtttcctca acattctcac ggtagtaata gtcaactgtt gcaccgtctt ctggtacgca
     4321 tttgcaggag ttgctaccaa ggtgtatgtt gttttccttg tgataactcg gtcttctttg
     4381 tcctcagttg ttgttttccc ttcaatagtt tttgattctg tggtatactc agaacctatc
     4441 gctaaatcag cttttataac agactctgcc aacttctctt ggctaccttc tttatagtaa
     4501 ttggctgtta ctgtagcagt ggttggcgct tcgctttctc tataaactaa ggtcactgtt
     4561 ctaccttcgc ttacaatatt cccagttaaa cttgcagaat ttgtatctgc ttctttaaaa
     4621 gtataatatt ttccgtcagt agtagtcatg ctactgagtt ttttatctgt gacattatag
     4681 ctggtaccaa tcagttgttt tttattggta atgtaggttc cgtcactttc tttttctcca
     4741 attccagtat catttttcaa tgatagcaaa cgcccttgtt catcaacata gcgaactttc
     4801 acattttctg agattagttc tgccaattct gaggtttttt tctttttctt gatttcttcg
     4861 gttattttcc ctttctcttc ttcgggaata tttagttttg gaatgatttt ttcaacaacg
     4921 gttcgtgatg gttccacagt atcttggatg actgaaaagt cagctagaat tgggagatta
     4981 tactgaacac ggtgactttg agtgtttact cctactcttt cattattctc tgaaaatact
     5041 cgtacggtat aagaaacaac atcttttcct aatagaacat ccccagtaga gaaatagccg
     5101 ccttttccta gtttgctatc tccagagtcc acttctttcc taatcttatc agatagtttt
     5161 ttaccagtca gtacattcgt tcgcacaatc cctttgtcta cccctacaaa gtgggagaac
     5221 tttttgaact cttcagaacc agatctagcc caaccattat taagggcatt tgcttttgta
     5281 tttgtattct ctctcaaagg tttggcgatt agaattatat tcatcggcac ttagagttgc
     5341 tgctatatct gactcttgaa taccaacttc cttactacca tttctagcgg cagtatatgt
     5401 gtatttatct gtttctactt ctagctgatt atccttaaca tgataggtaa ttttctcctg
     5461 gtataagagt cttcagtagt ttatatgctc tgtcatcatc tttagcttta gaagcagctg
     5521 agtttagcca agttggggta ttaggagtat ctttatcagc ctgtttcaag acattattca
     5581 agtcatttgc taacctattg gttgtcctca ctgtgaaagt tttcttccag tctgaatcac
     5641 ttttattaga cttagatatg ctcatgaaat cctggtcaac attcaacaca atatcgcctt
     5701 gttttttagc atcttccgtt gcttctgctt caaattgatc atggagtttt tgttgctctg
     5761 gtgtatagtt tttttattta cacgatttaa tgtactattt tttattttag tattaagaac
     5821 tccattaata cgatttttaa actctgcttc aaaaaatccc ttaatttgtt ggtgcgcaag
     5881 ttcaacattc aaacctttct tatacaagtc ttcattctga acgatttcgg ctacacggtg
     5941 aatggtttga tcgtataccg tcttctctta accagcagta tccttagttt taatgactac
     6001 tcgataggtt cctttagaac cgttatagtc atctagtttt aaaaaagcgt tccaaacatt
     6061 caaaaatagt tggaacttcc cttaataaat ccgtcacttt ctttttcaag atagcccaag
     6121 cttgctcaat aggattcaaa tccggtgaat aaggtggtag aggtaagaaa aagtgtttat
     6181 cttggatgca gagttcatcc aaaatgttct tgggatgaaa actagcattg cccatgacaa
     6241 taacatgagg tgtcttcaaa gcaggtagga gttgcgtttt gaaccactcc acaaagaaat
     6301 cgcttgtcat gcttttcttg taaatcatgg gagctataaa ctctccgcct acttgtcctg
     6361 caacaattga agttcgctca aaacgacgtc cgctaatctt ttcatagact ttctcccctc
     6421 taggagcccc tgcataggga cgatataggt agcggtcgat tcctgtttca tcaatatata
     6481 cgattggtaa atcttttagg ttatccaaaa tatcaagaaa ctcagcgact ttctctgact
     6541 cttgttcctt aaagctcgtc atcttttttt aaagtgacct taatctgctt taaagctgcc
     6601 catactgaag gaacagcaca atcaaaatgt gccgcaattt cccgtaaaaa agcatctgga
     6661 tgagcctcta caaaggcttt caattcctct aaaggaatct ttcggttttt gacgactcgc
     6721 tttttcctct ctatgtgtcc ttgttcacgt ctttcttttc ccacgtgaag agagttctga
     6781 cgccaacacc aaaaaacttg gctgcctcga catgactgtg cccctctttg atggaatcta
     6841 atgctcgctg tttaaaatca gtactatatg ccatagcttt attataacat gtattttata
     6901 aactaagcta ctatatcaat gttttgttat gagaagactt acttttttta ctgaaattga
     6961 atttttcctc gcctcaacat catataaccc caaaattcaa tctgacctgg tttgaagaga
     7021 tgttcgaagc agataaggtt ttactaaaac taaaaaaaat gatataatca aactgattaa
     7081 atgttttaaa aataaaggag aatttgaatg tcttaccaag aaaattacca gaaatgggtt
     7141 gattttgtgg agcttcctga ctatcttcgt caagatttgg aaaatatgga cgaaaaaact
     7201 aaggaagatg ccttctatac aaatcttgaa tttggtactg caggtatgcg tggcttggtt
     7261 ggtgctggta caaaccgtat caacatctac gttgttcgcc aagctactga aggattggct
     7321 cgtttgattg agtcaaaagg tggaaacgag aaagaacgcg gtgtagcaat tgcctacgat
     7381 agccgtcact tctcacctga gtttgccttt gaatctgcgg cagttcttgc taaacacggc
     7441 atcaaatctt acgtatttga aagccttcgt ccaactccag aactatcatt tgcagttcgt
     7501 catctcaact gtttcgcagg tatcatggtc acagccagcc acaaccctgc tccatttaac
     7561 ggttacaagg tttacggtga agacggtgga caaatgcctc cacacgatgc ggacgctttg
     7621 actacttata tccgtgcaat cgaaacccca tttgcagttg aagttgctga tgtggaaact
     7681 gaaaaagctt ctggcttgat tgaagttatc ggcgaagttg ttgacataga ataccttaaa
     7741 gaggttaagg acataaacat caacccagcc ttgattgaag aatttggtaa agacatgaag
     7801 attgtctaca caccacttca tggtactggt gaaatgttgg ctcgtcgtgc tcttgcccaa
     7861 gcaggatttg actctgttca agttgttgaa gcgcaagcaa ctgctgaccc agacttctca
     7921 actgtaacat cgccaaaccc agaaagccaa gcagcctttg cccttgctga agaacttggt
     7981 cgtcaagttg gtgcagatgt tcttgtcgca actgacccag acgctgaccg tgttggtgtt
     8041 gaagttcttc aaaaagatgg tagctacctc aacctttcag gtaaccaaat cggtgctatc
     8101 atggctaaat acatcttgga agctcacaaa aacgctggaa ctcttcctga aaatgccgct
     8161 ctctgcaaat ctatcgtttc aactgacttg gtaacgaaga ttgctgaaag ctacggcgca
     8221 actatgttca acgtcttgac aggtttcaaa tttatcgctg aaaaaatcca agaattcgaa
     8281 gaaaaacaca accacaccta catgatggga tttgaagaaa gcttcggtta cttgattaaa
     8341 ccatttgtac gtgataaaga tgccatccaa gccgttcttg tcgttgctga acttgctgcc
     8401 tactaccgtt ctcgtggttt gacacttgct gacggtatcg aagaaatcta taaagaatat
     8461 ggctactacg cagaaaaaac aatctctgtt actctttcag gtgtcgatgg tgctgaacaa
     8521 atcaaagcga ttatggctaa attccgcaac aatgctccaa aagaatggaa cgcaacagct
     8581 atcactgtcg tagaagactt caaggcacaa actgctactg ttgctgacgg tactgttaca
     8641 aacttgacaa ctcctccaag tgatgtgttg aaatacacac ttgctgacgg ttcatggatt
     8701 gccgttcgcc cttcaggtac agaaccaaaa atcaagttct acattgcagt tgtaggggaa
     8761 accaacgaag aatcacaagc taagattgct aacatcgaag cagaaatcaa tgcatttgta
     8821 aaataaagac ctataaaaga tgagaccaac caacctcatc ttttttcgta tcaaatctaa
     8881 gcaattttag aaactttatg gcatactaga cttatcaatg aaagcgaggt aatctcatgg
     8941 aacaattttt agataacatc aaagaccttg aagtcactac agttgtgcgt gcgcaagaag
     9001 ctcttgataa aaaagaaact gcaaccttct ttatcggtcg caaaacttgc ccttactgcc
     9061 gtaaatttgc aggtgcattg tcaggtgtcg tagctgaaac caaagctcac atttacttca
     9121 tcaatagtga agaaccaagc caactcaatg atttgcaagc attccgctca cgctatggaa
     9181 tcccaactgt accaggtttt gttcatatta cagatggaca aatcaacgtc cgttgcgact
     9241 cttcaatgtc agcacaagaa atcaaagatt tcgcaggatt gtaaaaaatc agctaacaag
     9301 tcttaaaatc acaaaaacgc ataatgtaag gtgcaaaaac cttgatatta tgcgttttat
     9361 tgttcctaaa acagttacat cagtatttca ttacagaaca ttttaatttt ggaagtcaaa
     9421 tcaattttta acaatgtttt agaaatcaca gtgggctatt ccatattcaa ttatccagat
     9481 tcaatcgcta ttatcgtttt cctagattac aaaaaaacta cgttttgcta atcaaaacgc
     9541 agtttcagcc actattttat cttactgtcc ttcttttact tctttggttg ctacatcttc
     9601 tccaaaccat ttttggctga tttcttggaa cttgccgtcc ttgtaaagac tagaaaaagc
     9661 ttcatttatc ttcttaacca aggttgtatc ttccttacgg gctccaaccg caaaagcttc
     9721 tgtttctagt ccaactgtaa agacattata atcgtttaaa acaccttctg cttctaaata
     9781 atagtttgca tagacacggt caatcaatag accatcaatt cgatcgtttt tcaaatcaat
     9841 caaggcttca ttaaaggttt ggtattgatt cgcttcctta ttagcgacaa tattcttcaa
     9901 aatttctgga tttgcttcaa agtccgcata accagatgaa ccagcttgag ctcctaatgt
     9961 ctttccagtc atatcctttg cagtcgtgat accagatgat ttcttcgtaa ccaatacctg
    10021 ctcattcttc atatatgagt tactgaaagc caccttttca cggcgttcgt ctgtagcgga
    10081 atagccattc caaatcagat caatcgttcc ttttgtcaat tcagcttctt tcaaatccca
    10141 atcaatcggt tgccaattta ccgtgattcc gtatttttca aaaacagctg tagctaaatc
    10201 aatatcaaat cctgcataag aaccatcttt ctgagcaaat cccattggaa caaaagtact
    10261 atcaaatcca atagtaatag acttgttaga ctggtacttt gaccaattat ctccactagt
    10321 ttcgctagaa tttttcccac aagctactaa gaacaaagca gtcatcagac tgactaatac
    10381 aagcatccat tttttcatcc atttttcctc ctatttaggt tctactttca ataatacatc
    10441 tgcgatattt tcagcaaact gcaaatcatg ggtaaccaca atctgggtca tcccaagttc
    10501 cctattttgc aagattagct tctccacttc caaacgtaat tctggatcca gggcagaagt
    10561 tggttcatcg tagccaatga tttctgggtc aatcatcata gcacgcgcca aagccacccg
    10621 ctgcttttgc ccaccagata gtgagaaagg ataggactct gcgtgtcctc ctagtcctaa
    10681 ctgttccaag agtccactcg ccttcttctc agcctcttcc tgcttcattc ccatggtctt
    10741 cacaggcgat aaagtcaaat tttccagaac tgatagatga ggaaatagtt gaaaatcttg
    10801 gaagacaaat cccagtaggt tgcgcttctg caattcatcc agctctaaag gttgtccatt
    10861 ataaaagatt tgccctgaat caatggtttc aagacccgca agcatacgta aaagagtcgt
    10921 cttacctcca ccagaaggtc caacgatagc caggatttgc ttttcaggaa tacttagact
    10981 gaaatcagac aggatttgtt tgtctccaaa gactttattg atatttcgta attctaacat
    11041 agctgccccc tatctataat aactgtactt tttctcaact tttttggaaa taattgtcac
    11101 aatcccaatt aaaatcaagt aaatagctcc tgccaagaac ataggaacca gactagcatc
    11161 gcggttagca gctgttcgac tagccaagat aaggtctgaa attccgagag cgtagaccaa
    11221 agaagtatcc ttgaccaaac tcataacttc attaaagaca ctaggaagaa cgatcttggt
    11281 cacttggggc aagataatat agcgcactct gtcaaaaggg ctaaacttca agaccttggc
    11341 agcctcatac tgtcctcttg gaatagtgtc aattccccca cggaaaattt ctgcaaagta
    11401 agctgcatag ttgagaacaa aggcaataat agctgcagga aggcggtcta aacgaatccc
    11461 aatacttggg agcacataat agataaaaat cagttgcaag agtaaggggg ttcctcgcat
    11521 aacccagatg taaatgttaa tcagataatg gaggggcttc caatggactt gcaaggcaaa
    11581 ggcaatcaaa acgcccaacg gaatcgaaaa tagcaagacc agtgcaaaga cctgtacagt
    11641 cgtgctcgca ccattcagta aactcggtaa tatctcaaat aaataagaca tactgcacct
    11701 cctaaaagta attgttccta ttatagcatg aataaacaag attaccaagt atttttgtaa
    11761 aaagattcta ccatatacaa ataaaaaccg tagctatcaa aagagataaa ctacagttct
    11821 atatgtttaa acattcttac aatctctcaa acagttcttg catttgcaca tcatctggaa
    11881 ccagttttaa gtaagtgtga gcatggactt ttgcttcttc aaaatgtccc aattcacgca
    11941 agagatagat atagtgttcc agaaattctg gattgtcctt caaatctcct gtcaactctt
    12001 gataatgctc ataagcagta tccaaatcgt ccatttcttg ataagaacga gcaatcatcc
    12061 acttggtcaa aagattttct ggctcctcac tctgcaagtc tagaatatcc tcataacgct
    12121 cctgctccag ataaatagtg gctaaacgaa gcaagatttc ttctgtatcc tcagcgtctt
    12181 cttttgcagt aaggagataa ttttctgcac cactagcatc atgcaattca taagaaaatt
    12241 gtgaagcagc tagcaagagg cgagtttcaa agggattttt ctctaatcct tgcttagcga
    12301 tacgcagggc ttcttgaact tgatgttcct tatgtaaagc ctgactgtac ccatactcat
    12361 agccttcaaa gtcaggagaa atggtattaa gctgcttaaa gtagagggtg gctttttgat
    12421 attcttcttg atcaaaataa agactggcca actcaaaagc tgttaagtca tcgtattcta
    12481 actccagggc tttttctaaa aactcagtag ccgtttcaaa tttccctaac tgagcatagg
    12541 caaagccaat tcgttgatag gtggaaatgc ccgtttgctc ataaatcgag cgattatcta
    12601 actgggcata ggcttgaata gccgcttggt aattttccaa ctcactatcc aactctgcca
    12661 aacccaatat caagagagaa tcctctgagt aggtcaaggc ctccaataat ttctcacgtg
    12721 ccacatctgt caaaccttcc agctggtaaa ggtctgcctt cagagccaaa gacgagacat
    12781 accagtcact gtcagcttgg atttcctcaa gataggtaaa ggcttcttct atttgaccat
    12841 cctcgctagc aattgcagct agattaagat gaacctctgg aaaatcctct acaattttca
    12901 ggtaaatttc cttggcctga ggatagaaac caatcccttc aagataagtt gccaactcat
    12961 acagaagatc acttgaatca ttttctaaag ctttggcgaa ataatgctca gccttagtta
    13021 aatcttgctc ctccaaagcc tgtaacatct gttgactatt gttcactctt gacttcctca
    13081 ccctctaatt catatagacc actgactacc ttataccatt cgaaaatggc tgaaatgaca
    13141 accttagcag aggcataaac cggaatacca agtaaaactc cccagatacc aaacatagat
    13201 cctgaagtta acaaaacaaa gagaacatta atagggtgga tgtttaattg acttcccaaa
    13261 atcaatggag agacaaaacg gccttcaata gtttgttcta caataaagac aatcactact
    13321 ttcaaaagca tgactggacc agcaatcaaa cccaatacta gggcaggaag catggctaga
    13381 aagctaccaa gataagggac cagatttaaa ataccagcag taacccccag cgtaaccgca
    13441 tagcgtagac caataatctt gaagaagatg ataaacatta ctgctacaat aatagccact
    13501 gtcacttgcc ctcgaacata gttggacaac tgttgattca catctgatag aacttgtcca
    13561 acaggttcct tcaattttct tggaatgaat tgggtcaaat agttacgcaa gcctttccca
    13621 tcacgcaaga gataaaagag catgaaagga acgataatca aggcaacaat cacttgagaa
    13681 gctccgctaa taaaggcact cacccagttg actgcctgag atgaaacctt acttgccaaa
    13741 actgtagcct ggctagaaaa attggtcaaa acttgctcta attgaggtct gaaatcatct
    13801 ggcaggtgct gggctaccaa tccattaaca atcctatcta tatcttctaa gtaaacagga
    13861 acgtttcttg caaaggtcaa aacctgacgt tgcagatttg gaatggcgac tgccaagccc
    13921 caaatgataa agagagcgat gataacaaag acaatagtga tagctataac acgattaacc
    13981 ttatgcttct ccatccaatc aacaatagga ttcaacaaat aatataacaa accagacaaa
    14041 atgactggca acatcacaac tgctaaaaag tctaaaacag gtgaaaatag aaaactaatc
    14101 ttacttaaaa taaaaagatt caatcccaat aataaggtta ctaaaaatac cgtaattgcc
    14161 ttgttatcta aaaaccactt gaaaaaccaa gataggctaa aatgtttctc tttttgctcc
    14221 ataaatactt cctttctatt gttctctcat tataccattt ttgaaacaaa ataactcttt
    14281 tttaaagtgc ttacatctaa ttgaatgtct ttaatttgct tgtttttgtg atatactagt
    14341 cttatcttta cacagaggta tagtaatgaa agaaactgtt tattttggaa cttatacacg
    14401 tcgtacttct caagggattt acaaggcaga ctttgataca gaaactggtc agctttcaaa
    14461 tctagaactt tttgcagctg agccaagtcc aacctacctt gcctttgacc agcaccaaca
    14521 tttatacact gttggtagcc aagacgataa gggggggatt gcagcctatc aaactgacgg
    14581 gactgtgtta aatcatgttg ttgaagaagg agctccccac tgttatgttg ctgtcgatga
    14641 aaagcgtgat ttggtttacg cagccaacta tcacaaggga caagtccttg tttataaacg
    14701 ccaggaagat ggtagtcttc tacttagtga tatggatcaa cacagtggcc aaggtccaca
    14761 tgaaaatcaa gcttcccccc atgttcacta tacagattta acacctgacc actatctagt
    14821 gacctgcgac ttgggaactg accaagtcat cacctatgac ctcgatcaag aaggaaaatt
    14881 atctaagctc tatacctatc acagcaagcc aggagcaggc tcacgccata tcattttcca
    14941 taaccactat aaaatcgctt atctcatttg tgaactcaat agtactatcg aagttttaat
    15001 ctacgatggc gttggcgaat ttgaacgtat gcaggtcatt tcaactttac cggaagctta
    15061 cgaaggcttt aatggaaccg ctgctattca tctctctaaa gacggtaaat acctctacgc
    15121 ttctaaccgt ggccatgatt ctatcgcagt atataccatc cttgcggacg gtagcttaga
    15181 gttattagaa atcgttccaa cgcatggtca gactccacgt gattttgatt tgacacccga
    15241 ccaaaaattt ctcattgttg tccatcaaga ctctgacaat gcaactgtct ttaaacgtaa
    15301 ttgtgacaat ggtcgtctag cagaactctc caacgacttc catgttcccg aagcagtctg
    15361 catccgtttt gctccttaaa acaccataaa aaatgaactt ggtattttca agttcatttt
    15421 ttcttatagt ctatttccga cattaatacg gttaatggca cgttgcaaag caatcttagc
    15481 acgacgttct tggtcaatca aatgtttgtc ttgtgcttct tcaattgcac gttctgcacg
    15541 aagtttggca cgttctgcac gactgatatc gatatcacga gcacgttctg cagagtcagc
    15601 gacgattgta atcatatcat tggcaatttc aataacgcca ccgtttactg caatccagtt
    15661 cacgtgatct ttatcatcga tacgttttac ctttacttca tcaactgcta aaaccgcaat
    15721 catattttca tgtcgtggca agatccccat ctcaccatcc agagttcgaa ccgatacata
    15781 gctggcatgg tgatcataga cgagaccatc tggtgtcacg atctggacag ttaactgagc
    15841 cataggtcac ctcttaaaat cccatttttt cagcttttgc aatcacatct tcgatagaac
    15901 ctacaccacg gaaggcatct tctggcaagt ggtcgtattt accatcaagg atttccttaa
    15961 agccacgtac agtttcagca actggaacat aagaacctgg ctgaccagta aattgttccg
    16021 caacgttgaa gttttgtgac aagaagaact ggatacgacg ggcgcgagca accaaggtct
    16081 tttcttcatc agaaagctca tccataccaa ggatagcaat gatatcttgc aattcatggt
    16141 aacgttgaag gacacgtttt acttcagcag caactgcata gtgctcttct ccaacgattt
    16201 caggtgccaa ggcacgtgag cttgaagcaa gtgggtcaac ggctgggtag atacccaatt
    16261 gtaccaactt acgttccaag tttgttgttg aatccaagtg agcgaaggct gttgctggcg
    16321 ctgggtcagt atagtcatcc gctggcacat agatagcctg gatagaggtt acagaaccct
    16381 tcttggttga tgtgatacgt tcttgcaatt gacccatttc cgtagcaagt gttggttggt
    16441 aaccaacggc tgatggcata cgacccaaaa gggcagatac ttctgaacca gcctgagtga
    16501 aacggaagat attatcgata aagagaagca cgtcttggcc ttccacatca cggaagtatt
    16561 cagcgattgt caaaccagta agggcaacac gcatacgtgc tcctggtggc tcattcatct
    16621 gaccaaagac catggctgtt ttctcgataa cgcctgattc tttcatttcc cagtaaaggt
    16681 cattcccctc acgagtacgt tccccaacac cagcaaatac tgaaatacca ccgtgctctt
    16741 gggcaatgtt gtgaatcaat tcttggatta agacggtttt accaactccg gcaccaccga
    16801 aaagtccaac tttaccacct ttaaggtaag gggcaagaag gtcaataacc ttgatccctg
    16861 tttcaaggat ttcagaagag gtagacaact catcaaaagt tggagctttt ttatgaattg
    16921 gctgacgctc tgcgtcttct gtaaaaggag cttccaaatc aatggtatct cccaaaacgt
    16981 tgaagacacg tcccaaagtt tctttaccta ctggtacaga gattggacga cctgtgtcca
    17041 atacttccat tccacgagtc aacccatctg ttgattccat ggcgatagta cgaaccatac
    17101 catctcctaa ctccaaggct acttcaagga cgatttttgt ttttctttcg tcatttttgt
    17161 agacgacaag tgcattatta atctcaggaa gtttttcccc tgctgcaaac aaaacgtcta
    17221 caacgggacc gataacctga gcaattttac ctgaactcat ctccttctcc tattctatat
    17281 aagatactgt cggttcctag ctcaactagg tcctaagttc attttcatac gagctggact
    17341 agagcctatt ctaaggcact agcacctgct acgatttctg taatttcttg tgtaatagcc
    17401 gcctgtctgg cacggttata ctgaattgtc aaatcattga tgactttctt agcattatct
    17461 gtcgctgttt gcatggctgt catacccgca gcattctcag ctgtcttggc atcgataatg
    17521 gcaccgtaaa tcatactttc tgcaaactga ggcaacaact gctccagaat ttcttctcgg
    17581 ctggtttcca attcaaaagt caagctgtac tcttcatccg cttcatttgg atccaagtca
    17641 acaatcggaa gcatttgttc cacacgcatt tgactggtta gcgtattgac atggtggttg
    17701 tagcaaacat aaagctcatc aaagagttca ttttggtaca tttcaacagt ttttgaaata
    17761 atcttacgaa cttgatcaaa gctaggttgg tctgacaagc cacgtaattc ataaagtggt
    17821 tgaataccgc gagccttaaa gaaatcagct cccatcccac cgatacagat catttcaaaa
    17881 cctttaccgt ctgggtggta ttcttctttc aactccataa cagctttcaa aatagaggaa
    17941 ttataacctc caaccaaacc gcggtctgaa gtgataacga tatagcctgt cttcttcaca
    18001 gaacggctaa tcaacatcgg attagttgaa gcaccagctc cattaccatg aaggatatct
    18061 gtcaaaagtt tacgcacttt ctgagcgtaa acttggaagt tgcgagcagc ttcttcagag
    18121 cgacctagct tagcagccga taccatttgc atggcattag tgatttgact cgtatttttt
    18181 gttgaggcga tttttgtttt aatatcattt agagacactg ccatctgaca cctctattct
    18241 tattggaagc tagattgatt gagaaactct gtaatcgcag catccaagac tgcttcttct
    18301 ggcaagtctt ttgtatcacg aatggtttcc aaaatctctg gatgttgagc atcaaagaag
    18361 gcatggaact cttcctcgaa acgaacaata tcatctactg gaacagtatc caagaaacca
    18421 tgtgtcaaag cataaagaat ggttacttgt ttctcaacag gtaatggttt gtgaacaggt
    18481 tgtttcaaga cctcaacggt acgacgtcca cggttcaact tagcctgtgt tgctgcgtcc
    18541 aagtcagaac caaacttagt aaaggcttcc aactcacggt atgaagcaag gtcgatacga
    18601 agtgtaccag caaccttctt catggctttg atttgtgcag aaccacctac acgagataca
    18661 gatgaacccg catcgatggc tggacgaata cctgcattga agaggccatc gccaaggaag
    18721 atttgtccat cagtgataga aatcacgttg gttgcgatat aggctgagat atctcctgct
    18781 tgtgtctcga taaatggtag ggctgtaatt gatccaccac caagttcatc agaaacttta
    18841 gctgagcgct caagcaaacg gctgtggaga tagaaaacat cccctgggaa ggcttcacga
    18901 cctggaggac gacgaagcaa gagcgacagt tcacgataag ctactgcttg ttttgataga
    18961 tcatcgtata caatcaaaac atgcttacct tgatacataa attcttccgc catagcaacc
    19021 ccagcataag gagctaggaa gagcaatgga gatggttgtg aagcagaggc tgtcacaacg
    19081 attgtgtagt ccaaggcacc gtactgacga agtgtttcta cttgcgtacg aactgttgat
    19141 tctttttgtc caatcgcgac gtagatacag atcatatctt gatctttttg gttcaagatt
    19201 gtatcaatcg caatggttgt tttccctgtc tgacggtcac cgataatcaa ctcacgttga
    19261 ccacgaccaa tcggtacaag ggcgtcaata gctttcaaac cagtttgcaa tggttctgaa
    19321 acagacttac gttgcataac accaggagct ggtgcttcta ctggacgagt tttatcagtg
    19381 tggatttctc caagaccgtc aactggacga ccaagcggat ccacaacacg accaatcaga
    19441 ctttcaccta cagggacttc catgattttc cctgtacggc ggattgtatc gccttcacgg
    19501 atatctgtaa agtcacctag gatgataata ccaacgtctg ttgactccaa gttttgagcc
    19561 ataccataag agccgttttc aaaattcaac aactctccac tcatgacatt ttcaaggcca
    19621 tgagcacgcg cgataccgtc cccgatatag gttacaacac ctgtttcagt cacatcaaaa
    19681 ttgggtttga aattttcaat ttgttgctta attaaagcgc tgatttcttg tgcgttaatt
    19741 gccaaaagaa caccactttc tatttcaaat tttctttaac aactttaagt tgttgtttaa
    19801 tactcacatc aattgtcttg tgattggcaa aaatgacaaa accaccaatg agactttcat
    19861 cgatttgttc ttttacactc cttactttca gagacatttt tttctcaatc aaagggagca
    19921 aacgagtctt ctgttcatca gttagaggat gagcagacgt aatcgtcact tcaaatcgat
    19981 ttgtttcttt ttcaagtcgg ttcaagcaat ctacaagcac atcataaaaa agatttgctc
    20041 tgtgattgta ggccagaacc tggataaagt tttgtaataa aggcgacaca gaatcttgga
    20101 aaaaagcaat tgttttttcc ttatccgact cgtctactgc cacttgtttt aaaaaagaag
    20161 gcagacctgt tttttcaaca acttgcttga tttgagtcaa gtctgaaaag atacggtctt
    20221 cttctccttt ttcaagtacc aattggacaa aaggcatgct gtatttttca attaccttta
    20281 ctgttttctt gtccattaag cttctcctag ctgatcgata tactgatcaa tgagtgcttt
    20341 atgggcatga ctgtcaaggt tttgtgagat gattttacca gctaagctga tggtcaaatc
    20401 tgcgacctca cccttaacac tctgtaaagc ttctacttta ttttgagcaa tttcttgatt
    20461 ggctttttct tttaagtgtc ctgcttctag tttagcatct gctaagatat tagccttact
    20521 ttgctcagct gtttcctttg cattttcaat gattgtctta gcttctttac ggctaccagc
    20581 caattcatct tcgcgttttt gagccaatac ttctgctttt tgacgggctt cttcagctct
    20641 gtcaatatct gaagcaattt tttcagctct ttcttcgaaa atgcctgtaa tattagacca
    20701 tgcaaatttt ttaatcaaga ctagcaaaag aataaaagag ccagtgatta aaataaaatt
    20761 accaattaat tcacctactg ttacgtgcat cagttactcc tttctattcc tcttcaatat
    20821 taatcttatt ccctaaatac acagatgtca aaagagtaaa aacataagct tggatgcagg
    20881 aaataaagac agaaaatgca gtccaagcca aattagctcc aaaggctact ggataccaat
    20941 aaatagcttg gtgggaaaga agaagtaaca aactcgtcat gacctctcct gcaaagatat
    21001 tcccaaaaat ccgcaaagcc aaagataaga agtttgtaaa ttcttccaag atattcatcg
    21061 gtatgacaaa aacaggactc ataaaagatt ttatactttt tttaaatcca cgacgacgaa
    21121 cgctttctat atgtgtcaac aaaatgacaa gaaaagataa ggttaagtca tactgtaaat
    21181 tagcggttgg cgaactccac cagttagtcc catcgatcgt ttgaatcttt gtcattaagc
    21241 caaggttatt ggcaatcacc atgaaaagga ataaacaaag gaaaaagagt gagtaatctt
    21301 tcatgtagcg cgaaccaatg ttaggttctg taaatccaat aacaaagtca tagacatact
    21361 caagtacatt ttgctttcct ttgggtttca aggtcatatt gcggcttgcc caataaataa
    21421 agacaaaaat aactcccaca atcaacaaag tcatggctaa catagtcaga ttgaagataa
    21481 caggaccaat agagatgatt ggattaatac tttcttccat ctaaaatcct cccttttctt
    21541 ctcgttccat gtatttattt gataataaat gagaagacaa gagttacaaa gaaagttcct
    21601 tcaataaagg caacacctaa aaacatcaaa ctacgaaact cagaaagcat atctggttgg
    21661 cgagctactg atttaaacag tccattcatc aataaacctt caccgacaga tacgcccata
    21721 caggcaatac ataagcctaa aaatgttaaa ttcataacaa attctccttt aaaataaaat
    21781 ttacttactt agtgtagtcc taaaatttaa atttgtcaac ttttaaccgc tattggaagc
    21841 gtttaataaa aattatttcc attttgctaa atttcaagtt caagttagcc atccagaagt
    21901 cttctctggg tgacttgtag tccaagcatt ttttaggata gttgttaatc cacttttcga
    21961 tgaatgcgac ttctttggga gtcattttct tggttccctt aggtaaccat ctacgaatga
    22021 gcctgttgtg attctcatta gttccccttt cccaagaggc atagggatgt gcataata
//
LOCUS       DAVKBC010000032        22046 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVKBC010000032 DAVKBC010000000
VERSION     DAVKBC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.032"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(1..1224)
                     /locus_tag="VWX64_001449"
     CDS             complement(1..1224)
                     /locus_tag="VWX64_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU9190906.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1393..2715
                     /locus_tag="VWX64_001450"
     CDS             1393..2715
                     /locus_tag="VWX64_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9190907.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2717..4603
                     /locus_tag="VWX64_001451"
     CDS             2717..4603
                     /locus_tag="VWX64_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU9190908.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            4771..5115
                     /locus_tag="VWX64_001452"
     CDS             4771..5115
                     /locus_tag="VWX64_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9190909.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLVEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5125..6537
                     /gene="lacG"
                     /locus_tag="VWX64_001453"
     CDS             5125..6537
                     /gene="lacG"
                     /locus_tag="VWX64_001453"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU9190910.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6607..8286
                     /locus_tag="VWX64_001454"
     CDS             6607..8286
                     /locus_tag="VWX64_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9190911.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPHGKV
                     INDTSAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QPISFVLLSLMLVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(8411..9850)
                     /locus_tag="VWX64_001455"
     CDS             complement(8411..9850)
                     /locus_tag="VWX64_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9190912.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMNNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSIDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(9854..11203)
                     /gene="trkA"
                     /locus_tag="VWX64_001456"
     CDS             complement(9854..11203)
                     /gene="trkA"
                     /locus_tag="VWX64_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU9190913.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRITYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11391..12239
                     /locus_tag="VWX64_001457"
     CDS             11391..12239
                     /locus_tag="VWX64_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU9190914.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12254..12802
                     /locus_tag="VWX64_001458"
     CDS             12254..12802
                     /locus_tag="VWX64_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU9190915.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            12809..13156
                     /locus_tag="VWX64_001459"
     CDS             12809..13156
                     /locus_tag="VWX64_001459"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190916.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     SKHGFEVVDRTDEVSSKHGFEVVDETDEVSNHTYGKAKLTWFEEIFEEYKMMGKAGQL
                     VFFDVYRLVRQVS"
     gene            13258..14940
                     /locus_tag="VWX64_001460"
     CDS             13258..14940
                     /locus_tag="VWX64_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190917.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPELQSLFRLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEEQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            14925..15755
                     /locus_tag="VWX64_001461"
     CDS             14925..15755
                     /locus_tag="VWX64_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9190918.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            15948..16451
                     /locus_tag="VWX64_001462"
     CDS             15948..16451
                     /locus_tag="VWX64_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU9190919.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      16505..16739
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            16904..17467
                     /locus_tag="VWX64_001463"
     CDS             16904..17467
                     /locus_tag="VWX64_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9190920.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            17481..18107
                     /locus_tag="VWX64_001464"
     CDS             17481..18107
                     /locus_tag="VWX64_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9190921.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFQALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIEQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            18134..18523
                     /locus_tag="VWX64_001465"
     CDS             18134..18523
                     /locus_tag="VWX64_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU9190922.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDRISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            18528..18977
                     /locus_tag="VWX64_001466"
     CDS             18528..18977
                     /locus_tag="VWX64_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190923.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDWHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            19105..19692
                     /locus_tag="VWX64_001467"
     CDS             19105..19692
                     /locus_tag="VWX64_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU9190924.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            20082..21689
                     /locus_tag="VWX64_001468"
     CDS             20082..21689
                     /locus_tag="VWX64_001468"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU9190925.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         6571 a         3746 c         4857 g         6872 t
ORIGIN      
        1 ttaaggtgaa ataatatctt gtaatacatt gctatgttct atgaaaaaag cgacgatagc
       61 taatgcacaa gctcctatac ttccacgatg tttgttgtaa ggtaaaattt caatttctat
      121 attacgagta aagggaacga agtggagctg gtcttggatt ttatccctga cttcatgagt
      181 gaaaggttga taattaagca attgactgtt gatatagatt ttatcagcag gattgatgag
      241 gaggagattt gcaatagaag tggctaataa attgactcct ttatcaattt gttgacgtaa
      301 agcggagtcg cctaaattat aagccgttaa aagggtgtct aaatgaatgt ctttttcagt
      361 ctttacaagg ctttttagta cagttagttg ggaattttta aataataatt gggcgtgttt
      421 gattaaccaa gcatccgaaa tatatgtttg taaacaacct ttttttccac attcacaata
      481 ttgcccattc aattcgacaa tggtgtgtcc aatttctccg atataaggat ttttagaggc
      541 tcctattttt tcttttgtga aaaaggaagt gtaaatacct aatccagcgt gtaggaaaat
      601 aaagttatcg ggggtattgt gtggattaaa aaggtattgt cctatagcca tacaatcgat
      661 attatttttt acaataaaag gaaaattgaa tcttttaatt acatttaata aattaaaaga
      721 ttcccatatg gggttgtttg taatgatact tccggagtct ttgttataat gtccaggtat
      781 tgataagcca aatccaagta attttgtttc caaagggacg tactctatag ctgtttttat
      841 catattggta atggtggaat tgatttctga aataggataa tcttcattca aaatttctgt
      901 ctcgaaaaga gttttccctt gtaagtcaca tagactgaga aagataccta ggacgtttat
      961 ttcaatacct ccaacaacat acggaatatt atctgtgata gaaatagttt ttctacgtct
     1021 tccagatccg gaaaactcgc taaattcatc accagtttcg tatatgaggg actgttcgct
     1081 tagctctttt atgatgttag tcgttgttgc tggagtaagt cctgtttcat taacaatatc
     1141 tgtacgggat gttgctggat ttcgatatag aaactccagt atagtggctc tattttgtaa
     1201 aaaggctgat tgttttgtaa tcatttgttt cctcctttgg tttattttat attaaacata
     1261 agaaaaaatc aattaaaatt attattctat acaaagaaaa aaatattgta aaaacaacaa
     1321 aaaaatatat tgacaacgct ttctgttagt ggtatattta atttataaaa aataaaaaaa
     1381 ggagttccgg tgatgaacaa tattttagcg tttttagaaa caaaagtcgc tccgtttggt
     1441 gaaaaagttg gcaaccaacg gcatttgaaa gctattcgtg aaggatttat gatggcaatg
     1501 cctttgattt tagtcggctc tttatttctt attctaatca gttggcctca agaggatttt
     1561 acaaattggc tgaatagtgt tggattgcta agtatcttga caactatgaa tcagtcaaca
     1621 gtagcgatta tctccttggt cgcttgtttc ggtattgcct acaggttgtc ggaaggatat
     1681 ggtacagatg gtccgtcggc agggatcata gccttatcca gttttgtatt gatggcacct
     1741 cgtttttcga gtatggttta tgataaaaat ggggagcagg tcaagcagtt atttggcggc
     1801 gcaataccat tttctagcct gaatgcatct tctttgttta tggcgattac tattggattg
     1861 gttacagcag agatttatcg tatgtttatc cagcgcggaa ttacgataaa aatgccaagt
     1921 ggtgtcccag atgtggtaag taaatcattt tcagctcttt tacctggctt tactactttt
     1981 gttttgtggg ctctggtctt aaaaggtctt gaagcggcag gagttgcagg aggtctcaac
     2041 ggactcctag gtgcaattgt tggaacaccg cttaagttaa ttgcaggaac gcttccaggt
     2101 atgattctat gtgttattgt aaactcattc ttttggttct gtggagttaa tgggggacaa
     2161 gttttaaatg cttttgtaga tccagtttgg ttacaattta ctacagaaaa ccaagaagct
     2221 gtggctgcag gacaaacact ccaacacatt attacattac cgtttaaaga tttatttgta
     2281 tttattggtg gcggtggagc gactattggt cttgcgattt gtctcttcct atttagtaag
     2341 agtcgtgcga ataaaacatt aggtaagtta gctattatac cgtctatttt taatatcaat
     2401 acagctattc tatttacgtt tccaacagtt ttaaatccga ttatgctgat tccgtttatt
     2461 gctactccta caatcaatgc cttaattacc tatgtatcaa tggctgtagg attagtaccc
     2521 tacacaacag gtgtaatcct tccgtggaca atgccaccga tcataggagg cttccttgcg
     2581 acaggagcta gttggcgagg agctctatta caagttgttt tgattttggt ttctgtagca
     2641 atttattatc cattcttcaa aattgcagat aaacgcaatc ttgaaaaaga aaaagctact
     2701 gttggaggga aataagatgg ttatcagagt atttgatcag cagaaaaata cttattctag
     2761 ctttgcctta gaggaattaa gttactatat aaatcgggtc tttaagactg acatagaact
     2821 tgtcgaggag aaggaagcgg atatttttgt aggattagtc aataaagagg atagaaaaga
     2881 ccatgttctt atctcattag acaagggtaa ggggagaatt gagtctaata caattgtagg
     2941 tttacttatt ggaatttacc gaatgtttca tgaatttggg gttgtgtata ctagaccagg
     3001 gcgcggacat gactttgttc cagagttacg atttgaagat tttttagata aagagctatc
     3061 tatagatgaa acagccagtt actatcatag gggagtatgt atagagggag cagattcatt
     3121 tgaaaatata ctagatttca ttgattggct acctaagatt gggatgaaca gttttttcat
     3181 tcagtttgaa aatccctatt cttttttgaa acgttggtat gaacatgagt ttaatccata
     3241 cctaaataaa gaaaaattct caaatgaatt agtacaagaa ttgagtgata ggttggataa
     3301 agaattgcaa aaaagaggtc ttattcatca tcgtgttggt catggatgga caggtgaggt
     3361 tttaggttac tcttcaaaat ttggctggga atcaggtctt agtatttcag aggagaagaa
     3421 accgtatgtc gctgaaataa acgggaaacg agaattattt aatacggctc cgattttaac
     3481 cagtctggat ttttcaaatc cagatgtggc ggataagatg gtagaaatta tcaaggatta
     3541 tgccaagaaa agacctgatg ttaactactt acatgtatgg ttgtcggatg ctcgtaataa
     3601 tatttgtgaa tgcgaaaact gtagacaaga attggtttcg gatcagtata ttcgtattct
     3661 caatcaattg gatagggctt taacgagtga gggattagat acaaagattt gttttctgct
     3721 ttaccatgag ttgctatggg cgcctcagaa agaaaaatta gataatcctg aacgctttac
     3781 catgatgttt gcaccgatta caagaacatt tgaaatgagt tatgcagatg tagattttga
     3841 caattccata cctacgccta aaccttatct gcgtaataaa attatacttc cgaattctct
     3901 tgaggaaaat ttatcttatc tttttgagtg gcaaaaaaca tttaaaggag atagtttcgt
     3961 atatgactat cctttagggc gtgctcatta tggcgattta ggctatatga aaattagtca
     4021 aaccatttac agagatgtat cttatctttc taacctacat ttgaacggtt acatttcgtg
     4081 tcaagaatta cgtgccggat tccctcataa ttttcctaat tatgttatgg gggaaatgct
     4141 ctggaagaag acaagaagtt atgaagaatt gattgaagaa tacttttctg ctttgtatgg
     4201 gtcaaattgg cagtctgttg ttgaatattt agaaaaatta tccagttatt cctcatgtga
     4261 ttattttaat gcaattggca gtcgtcaaaa tgatgtttta gcgaatcatt attatatagc
     4321 ttacaatcta gctgataatt ttttgccaat tattgaggaa aatatttcta agttattaaa
     4381 tagtcaaaag gatgaatgga aacagctcag ttatcatcgt gaatatgttg ttaagatggc
     4441 gaaggcttta tatcttcaag caactggaaa aacaaggcaa gctcaagatg aatggagaaa
     4501 tgtgttgaat tatatccgtg ggcacgaact gctattccaa tctaatttgg atgtttatcg
     4561 tgtaattgaa gtagcaaaaa attacgctgg tttccactta taaatcataa gtatagaaaa
     4621 tgaaccaagg tattcagaga agattgatcc taaatattat gaaatttaag gatttttaag
     4681 atatttaggg tcaactttct atttatatcg tagcgaagtc attttaataa tgatgtgtaa
     4741 aagatggatc aagattgagg aggaagaaag atgaaatcaa aagaagaaat aaatatgctt
     4801 ggttttacaa ttgtcgctta cgcaggagat gcaaggtcag atttgatgga tgctttggcg
     4861 tttgcgagag atggatattt tgaacaggca agagaattgg ttgagtctgc aaacgactca
     4921 atagtgtctg cccatcgaga acagactaat ttattagtgg aggaggcatc tggagataat
     4981 tttgaagtga gttttatcat gattcatggt caagatacct tgatgacaac gatgctattg
     5041 tatgatcagg tcaagttttt tattgatgaa tatgaacgaa ttcgaaagat tgaagaacat
     5101 attggtttgc aatgaggatt agtcatggaa aatttacagg ttaaagcctt accgaaggag
     5161 tttttattag gagctgctac cgctgcttat caagtagagg gtgcaactag ggtagatggc
     5221 aaaggaacaa atatgtggga tgtttatttg caagaaaaca gtccgttctt accagatcca
     5281 gctagtgatt tttattatcg ttacgaagag gatatagctt tggcggcaga acatggtttg
     5341 caggctttgc gtttatctat ttcttgggtt cgtatatttc ctgatataga tggggagcct
     5401 aatatattag ctgttcgtta ttaccataga gtctttcagt cttgcttaaa acataatgtg
     5461 attccgtttg tttctttaca tcattttgat tcgcctcaga aaatgttaga aacaggggat
     5521 tggttgaata gagagaatat tgatcgtttc atacgatatg ctcgcttttg tttccaagaa
     5581 tttacagaag tcaagcattg gtttacaatc aatgaactga tgtctcttgc tgcaggtcaa
     5641 tatataggag gtcagtttcc tccaaatcat cattttcaat tatctgaagc aattcaagcg
     5701 aatcataata tgttgttggc gcatgctctt gcagtcctcg aatttcatca attaggaatt
     5761 gagggagaga taggttgtat tcatgcttta aagccaggct atcctattga tgggcaaaaa
     5821 gaaaatattt tagcagctaa acggtatgat gtttataata ataaatttct attagatgga
     5881 acttttttgg gctactacag tgatgacacg ctttttcact tgaatcaaat attggaagct
     5941 aataattcta gctttattat tgaagatggt gatttagaaa ttatgaaaag agctgcacct
     6001 cttaatacga tgtttgggat gaattattat cgttcagaat ttattcgtga atacaaaggt
     6061 gaaaatagac aagaatttaa ttcaacagga ataaaaggac agtcttcttt taaattaaat
     6121 gctctaggtg aatttgtaaa aaagcctggt attccgacaa cagattggga ttggaatatt
     6181 tatcctcaag ggttatttga tatgttgctt cgtatcaaag aagaatatcc tcaacatccg
     6241 gtcatttatt taactgaaaa tggtacagcc cttaaagagg ttaagccaga gggcgagaat
     6301 gatattattg atgacagtaa aagaatccgt tatattgagc aacatttaca caaagtttta
     6361 gaggctcgag ataggggagt caatattcaa ggctatttta tatggtcttt gcaagatcaa
     6421 ttttcttggg cgaatggcta caataagcga tatggtcttt tctttgttga ttatgaaaca
     6481 cagaagagat atattaagaa aagtgctctt tgggtaaaag gattaaaacg gaattaaggt
     6541 tagcgatttg actgatgttt aatatatttt aactatgagc ttaaattttt tacaggagga
     6601 gtttttatgg ataagttagt cgctgccatt gaaaagcaac aagggaaatt tgaaaaaatt
     6661 tctactaata attatatgat ggctattaaa gatggattta ttgctactat gcctttaatt
     6721 atgttttcaa gctttttgat gattattatt atgattccta aaaatttcgg agtagagtta
     6781 ccgagtccag ctattgcctg gatgaggaaa gtgtatatgc taaccatggg agttttgggt
     6841 attattgttt cagggacagt tgcaaagtca ttggctggaa atgttaacag aaaaatgcct
     6901 cacggaaagg taataaatga tacttctgca atgttggcag ccatatgtag ttatctggta
     6961 ttaactgtaa cgcttgtagt tgatgagaag acgggatcta caagtttgtc gacaaactat
     7021 ttaggatctc aaggattgat aacttcgttt gtcagtgcct ttattactgt aaatgtttac
     7081 cgattctgta ttaagcgaga cattactatt catttaccta aggaagttcc tggggctata
     7141 tcacaagctt ttagagatat ttttcctttt tcttttgttt tacttattag tggtttgtta
     7201 gatattgtat ctcggtttag tttagatgtt ccttttgccc aagtatttca acaactattg
     7261 actcctattt ttaagggggc agaatcatat cctgctatga tgttgatttg gtttatgtgt
     7321 gctttgcttt ggtttgttgg aattcatgga ccatctattg tcttacctgc tgttacagct
     7381 ttacaactga gcaatatgga agagaatgct caacttcttg caaatgggca gttcccttat
     7441 cattctttaa cacctaattt cggaaattat atcgctgcta ttggaggaac gggggctacc
     7501 tttgttgtac catttatttt gattttcttt atgcggtcta aacaattaaa atcggtaggt
     7561 aaagctacaa ttactcctgt tttatttgcg gtaaatgaac ctcttctatt tggtatgcct
     7621 gttattttga atccctatct ttttgtccct tttttgatga ctccaccagt gaatgtattt
     7681 ctaggaaagg tatttattga tttctttgga atgaatggat tttatatcca gttaccttgg
     7741 gcctttcctg gtcccttggg attgttaatt ggaacgaatt ttcaacctat ctcctttgtg
     7801 cttttatctt tgatgttagt tgtcgacata ttgatttatt tgccattctg tagagcgtat
     7861 gatagacagt tactgatgaa agaagatgtt gcaagctcaa atgatattat tttagaggag
     7921 gatacaagtg aaataatgcc tggtgagata gatgtaataa aaagtaagga gttgaaagta
     7981 ctggttcttt gtgcagggtc tggaacaagt gcgcaattag ccaatgcaat taacgagggc
     8041 gctcaattag cagaagttag agtgattgcg aattcaggag cgtacggagc tcattatgat
     8101 attatgggtg tttatgattt aattattctg gctccacaag ttcggagtta ttatagagag
     8161 atgaaggtgg atgcagaaag attaggtatt cagatagttg ctaccagagg aatggaatat
     8221 attcatttaa caaagagtcc aagtaaatcc ttacaatttg tattggagca ttaccaagct
     8281 gtgtagtaag tttttccatc ttttatttga gtaaggactt tgcttacaga caggcttgga
     8341 tttaaaaacg ttcccccttt ttaatataaa aatccctctt tcacaattgt aaaaagaggg
     8401 attttgtatt ttatctctta gaccaagttc tcttcataaa gagaaggagg attgggtaaa
     8461 tctccaagcg gcctgcaatc attgcaaagg agaggagaat ttttgagata ggactaaaga
     8521 ttgagaaact agaagtggtt cctagaatag gcccgatatt attgaaacag ctaaagacag
     8581 cgctggtcac gatcagaaaa tcattgctat ctatgctgac aataaagata agggatagca
     8641 aaatcatagc atagatgaca aagtacttga gaatcttatg ctgggtatct ttatcaatca
     8701 ccgtttgatt cacatggagg gtcaaaacac ggtggggcga taggattgac aaaatttggt
     8761 ttttggcaat ttttgaaagg atgaggcctc gaataatctt gagtccacct gcagttgatc
     8821 cagcagagcc accgattgtc atgaggaaga ggaggataaa ctgggagaag aggggccagt
     8881 tggtaatatc tccatatcca aaaccagttg ttgtaatgat gttggaaacc tggaagaagg
     8941 ccatttcaaa gctctttgaa aaccctgggt agaggtagag ggtgttgagg ctaatcaagc
     9001 ctgtagaaac cagcacgatg accaagtaag cccgaagctc ttcatctcca aagaaggcct
     9061 taacccgacg gagcataagg tagtagtaga gattgaaatt taccccaaaa accaaaactc
     9121 ctatactaac cagataggta atcagtgagc taccatagtg ggcaattcca tcgttataga
     9181 cggtaaatcc tccagttccc gctgtcccca tagcaatgac aaaactatcg tagagaggca
     9241 taccggctag ataatagatg atgacaaaga gggaaaagag ggctatgtaa aggagataga
     9301 ggatctgggc agtgtttttt aatttggata caaccttgcc aaaaacagga cctggaacct
     9361 cagccttcat cacctctagg tggctatttt tggcattgtt cataatagca agtgcaaaaa
     9421 caagcactcc catccctcca atcaagtggg taaaacttcg ccagaagagg agggaacggc
     9481 tgagaaccga aacgtcgttc aaaatacttg ctccagtagt tgtaaaccca gaactaattt
     9541 caaaaaaggc atcaataagg ctggggattt gcccagaaaa gacaaagggg agaccaccaa
     9601 agaaagacca aaggatccaa cagagggcaa cgatcaagac tccctccttg gcataaatcc
     9661 gttgattttt tggcttctgt aaactccctg aaccgcctaa caatacgaga atccctatgg
     9721 tcgaaaagag ggctgtaaag acttggctcg attcacggta atagacagcg atagccacag
     9781 gaaccaagag gagaacagct tcaatcaaaa gtaactttga aaggaggtaa cgaatcatac
     9841 ttttattcat ttcttacctc gcaatcaagt cataaatctt ggtgatgttt ggcaacaagg
     9901 ttgttactag gagcttgtct ccaacttcca acatatcctc cccagttggg aaaatagtct
     9961 tgccctttcg aataatggct gcaataagaa cccctttttt caatttcagt tgagaaagag
    10021 gtttggcagt cattttattg gcttccttga tatggaattg cagggtttcg atttggccat
    10081 tggctagatg gtgcatggct tgaaggtctg aatactgggc attaactcga ccacgaataa
    10141 agtgcataat cgtatctaca gcgatgcttt taggtgtgat gatacttgaa aaatcaggcg
    10201 cattgataat ctcgaggaga ctggtacgat tgaccttagt aatatttttc tgtacaccta
    10261 ccctgtcaag gaacatagat gtaatcagat tttcctcatc gactcctgtt agagtcgcaa
    10321 cggcatcata gtgttgagca ctttcttcca gcaggatatc ttttgcggtt ccatctcctt
    10381 gaacgatgta gagatttggg aatttctcgc taaagaagct ggcgatttca ggattgattt
    10441 caatgacttt tgtatcgata cgactatctt tgagaatacc aagtagataa taggtaattc
    10501 tacctgctcc aacgatgaga aggctcttca cggcgcgtga tttaaaataa ttatggaaga
    10561 gtatcatatc gacacggtta ccagtgacaa agattctatc tttatcctgt acagtcatgt
    10621 caccgcttgg aatgataatt tgatgatccc tctctatcgc acagacaatg acattaccaa
    10681 attttttacg aaaatcagaa atgggcattt ggcaaagacc gctggtggac ttgacgacaa
    10741 attccatgag gctaacgcgt ccaccagcaa agcgttcgac agacagggcg ttggggaagt
    10801 caatgatatt cgcgatagcg cgggcagcca agagctcagg attaacgata agagaaaaac
    10861 cgagaatatt cttttccttg aaataagagt tagaatattc agggttccgc acccgaacga
    10921 tagtttcttt agctcccatt ttcttggcta gaactgctgc aatcatgttg acttcatcgt
    10981 gctcagtcag ggcgataaag atatcacaat cttggacgct ggcttgctca agaatggcaa
    11041 aatcggcccc gttaccaagg ataccaatga tatcaaagcg actgacaata tgattgagaa
    11101 cagcttcgtc ttgctcaatc agcaaaacat catgcttttc tgcaaccaag gagcgacaga
    11161 gggcaaaacc aacttttccc cctccgacaa ggataatttt cataataaaa cctacttttt
    11221 catgatgtaa ctatcatacc ctttttcaag aaaaaatgca cctactagct aataacaaga
    11281 gcttttagtg aaaattcgct ataaggtaaa actataccct aaccaattga aatagctatt
    11341 agcgactttc tctgaaatat ggtatgataa aggatataca aggagataaa atgaataata
    11401 atttactggt attacaatca gactttggtc tggttgatgg tgcggtatcg gctatgattg
    11461 gagtggcttt agaagagtct ccaaccttaa aaatacatca cttgacgcac gatatcacgc
    11521 cttataatat ttttgagggg agctatcgtc tctttcagac ggtggattac tggcctgagg
    11581 gaacgacgtt tgtatcggtt gttgatccag gtgtcggttc gaaacgtaag agtgtagttg
    11641 ccaagactgc aaaaaatcaa tacattgtca cgccagataa tgggacgctt tcctttatca
    11701 agaaacacgt tggcattgta gccattcgtg agatttctga ggtggccaat aggcgtcaaa
    11761 acacagagca ttcttatacc ttccacggtc gtgatgtcta tgcctatact ggtgctaaac
    11821 tggccagtgg tcacattact tttgaggaag tagggccaga gctcagtgtg gaacagattg
    11881 tagagcttcc agtcgtagcg accatcatag aagatcatct ggtgaaggga gccattgata
    11941 ttctggatgt gcgtttcggt tcgctttgga cctctatcac acgggaagaa ttttacaagc
    12001 tggaaccaga atttggtgat cgttttgaag tgaccatcta tcatgctgat atgctggtct
    12061 atcaaaatca ggttgtctat ggcaaatcat ttgcagatgt gagaattggg caacccatcc
    12121 tttacatcaa ctctctctat cgtttaggtt tggctatcaa ccaaggttcc tttgccaagg
    12181 cctataatgt aggtgtcggt tcatcttgga ccattgaaat aaagaaaata gaaggataaa
    12241 ataggagaat agtatggaaa tcaaatttac aattaaacaa gttgttgctg tcggaattgg
    12301 cgctgccctc tttgtcgtca tcgggatgat caacattcca acccctgttc caaatacaag
    12361 catccagctt cagtatgcgg tacaagcgct actttctatt atttttggac cgattatcgg
    12421 tttgcttgtc gggttgattg gtcatgcaat caaggactct cttgttggtt atggtctatg
    12481 gtggacttgg attatcgcta gcggactctt tggtttagtt gtgggacttt ttagaaagta
    12541 cgttcgcgtg atcaatggtg tttttgactg gaaagatatt cttattttta acctcattca
    12601 actacttgca aatgcccttg tttggggtgt cttggcacca cttggagatg ttgtgattta
    12661 tcaagaagcg gcagaaaaag tatttgcaca agggattgtt gcgggaattg ccaatggtgt
    12721 atctgtagct attgcaggaa ctcttctctt acttgcctat gcaggaaccc aaactcgtgc
    12781 aggaagtttg aaaaaggact aatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    12841 cgcaggttgc tcaaaacagt gttttgagat tgtggataga actgacgaag tcagctcaaa
    12901 acatggtttt gaggttgtag atgaaactga cgaagtcagc tcaaaacatg gttttgaggt
    12961 tgtggataga actgacgaag tcagctcaaa acatggtttt gaggttgtag atgaaactga
    13021 cgaagtcagt aaccatacct acggcaaggc gaagctgacg tggtttgaag agattttcga
    13081 agagtataaa atgatgggga aggctgggca actagtcttt ttcgatgttt atagattagt
    13141 taggcaagta agctaggata ggaatctttt tggcgctaag attttaagag aagagactgc
    13201 aagaagggct tgatttatga taaaatagaa gtctaagaag cgaatgaaga gagtaagatg
    13261 aaagaagcta taattgagtg gaaggatttc tctttccggt atgaaacaca acaagaaccg
    13321 accttgcaag ggatagactt gaccatttac aagggagaga aagtcttaat tgttggacca
    13381 tctggatcag gtaaatctac cttgggtcag tgtttgaatg ggattattcc caatatttac
    13441 aagggtcaga catatggaga atttttgata aagggtcaag tagcctttga tatgagcatc
    13501 tatgataagt ctcatctggt tagcacagtt ttgcaggata cagatgggca gtttattggc
    13561 ttgtctgtgg cagaagattt ggcgtttgct ctggaaaatg atgtgacagc cctagatgag
    13621 atgaaaggtc gtgtttataa atgggctgaa aagctggacc ttcttccttt actggatcag
    13681 cgtcctcagg atttgtcagg tggacaaaag cagcgagtca gtctggctgg tgtcttgatt
    13741 gatgaaagtc cgattctctt gtttgatgag ccactcgcca atctagatcc caagtcaggt
    13801 caggatatta tcgaattgat tgaccagatt cataaggaag aggggacgac gactctgatt
    13861 atcgagcacc gtttggagga cgttctgcat cgccctgtgg atcggattgt cttgataaac
    13921 gatggtcgta tcctttttaa tgggagccct gaccagttgc ttgcgactga tttattgact
    13981 caaaatggaa ttcgagaacc cctttatcta accactctcc gtcaattagg tgtggactta
    14041 gtcaaggaag aacaattagc agatctggat aacttgtcta tctcaaaagg gcaagtccag
    14101 ttacagacgg aactggtaaa agaaacccca gaattgcagt cactctttag actagaggac
    14161 gtgtcttttt cttatgatga tagaccgatt ttaaaatccc tacatttaga tattaaaaag
    14221 ggtgaaaaga ttgctattgt cggaaaaaat ggagcaggga aatcaactct agccaaggct
    14281 ataagtagct ttattcagac ggaaggacgc tatctttggg aagaacagga tataaaaggc
    14341 gattctgttg cagagcgggc ggaacgagta ggctatgtgc tacaaaatcc taatcaaatg
    14401 atttcaacca atatgatttt tgatgaggtg gctctagggc tccgtttgcg aggtgtggat
    14461 gagaaggaaa ttgaaacgag agtctatgaa accttgaaaa tctgtggact ttatgaattc
    14521 cgtaattggc ctatttctgc cctgtcattt ggtcagaaaa aacgtgtcac cattgcttca
    14581 attttggtct taggagctga aattattctc ctagatgaac cgactgcagg tcaagatcag
    14641 aagaactata ctgagattat ggaatttctc gaagagttac atcaaaaagg gcataccatt
    14701 gtcatgatta cccatgatat gcaattgatg ctggattatt cagaccgggt ccttgtcatg
    14761 gtggatggag aattgattgc cgatactgtt ccagccagtc tgttgagcga tcctgagctg
    14821 ttagtaaaag ccaatctaaa agaaacctcc atctttaact tggctaagaa actagatgtg
    14881 gatccactgg atttaacggc attttacaaa gaaaggagag agggatgcaa gctaaattaa
    14941 tcggttacca gcatagagat actgtgattc atcgcttgtc aggagctggg aaacttctct
    15001 ttttcattct ggtatcattg gcggccatga ttagctatga taccagaatg ctcttgctga
    15061 ttgccatctt ttcagtcttt ctcctctatt tatcagaaat tcgctttaaa gatgtttcct
    15121 ttgtagccgt ttttgcgacg gtatttgccg ttttaaacgt tttgatggtc tatctctttt
    15181 ctcccgagta tggggttgga ctttatggag agagaagtgt gatttggcag ggaatcggtg
    15241 tctacactct aaccagccag gagctctttt atctgctaaa tttggccatt aagtatcttt
    15301 gcaccattcc tctggctatt atctttttga tgacaaccca tcctagtcag tttgcttcca
    15361 gtttaaatca aattggtgtg ccctataaga ttgcttattc tgtcagcctg accttgcgct
    15421 atattccaga tttgcaggaa gaattcttta ctatcaagat gtctcaggag gcgcgtggga
    15481 tggaattatc caagaaagct tctcttatgc aacgaatcaa aggcaatctg ctcattatta
    15541 cgcccttgat ttttagctcg ctagaacgca ttgataccat tgcgactgcc atggagcttc
    15601 gccgctttgg gaaagagaaa aaacgcacat ggtatagtta tcaggccttg aaaaaaggag
    15661 actatattac cttgctcttg gcaaccttgt ttttagtagt tagtttacta cttatcttgc
    15721 agaatcaggg acgattttac aacccttgga aatagcttga aaaaattgaa aaaatcaagt
    15781 catttctatt gacaatgatt ctgaaagtgt tatactaaga aagtagtttc gctgatttac
    15841 ttcaaacctg ttgtgaggta agttaacgat gccttaacca cgctgtttgc tgagcttgac
    15901 tccgggcagt gtggctattt ttttgcaatg gtgaaaggaa gcaagtcatg acaaatcaca
    15961 ttgtattatt tgaacctcaa attccacaaa atacaggcaa tatcgcgcgt acttgcgctg
    16021 cgaccaattc tcccctccac atcatcaagc ctatgggctt tcctattgat gaccgcaaga
    16081 tgaagcgggc tggattggat tactgggata agctagagat ttatttttac gagagtttag
    16141 aagatttcat atctcagatg aagggaaaac tctatctgat ttcgaaattc gcggaaaaaa
    16201 tctattctga ggtggattta tcgactgacg aggaccatta ttttctcttt ggacgtgaag
    16261 acaagggctt acctgaagat tttatgcgag aacatcctga gaaggctctc cgtattccca
    16321 tgaatgatga acatgtccgc agtctcaatg tgtctaatac cgtctgcatg attgtctatg
    16381 aggctcttcg ccagcagaac tttgcaggtc ttgagctcgt ccatacctat gaagtggata
    16441 aattgaaata aaaaatgaaa atgaacaaaa tgcttgcgct tgcaagcgtt ttttgttatg
    16501 ataaaagagt cttcagggca gggtgtgatt cccgaccggc ggtgacttta actaggaaat
    16561 gatcttttcc ttttatactt tgttgacaag ctttgcctaa ccagaagtta tgcctacagc
    16621 ttgtcgccta gtctaaaaga aaaatctcta tttctttctc tttaaagaag tccgcgagcg
    16681 caagctgatg tggtgagatt ccacaaccga cagtatagtc tggatgggag aagacgaaag
    16741 aatagctttg tctgttttga tagatttata gccggattgt aaccacttgc tttgtttttc
    16801 tttaatagag taagagggaa cttttgggat ataaaaagtg agaatagata gaggaatcct
    16861 ttccaacttc ttctgatttt atagaaaatt ggaggaacct gttatgacaa acacacgtcg
    16921 actttcgacc attgcaattc tatcagccat ctcatttgtg ctgatgtact ttgactttcc
    16981 gcttttacca gcggcatctt tcctcaagat cgaatttagt atcttgccag tccttgtggg
    17041 tctggtggtc atggatttgc ctgctgctct aggagtgctc ttgcttcgct cactcttgaa
    17101 gttgcttctt aacagccaag gagtgaatac ttacattggt ttgccgatga atatcgtagc
    17161 tttgggagtt tttgtcatcg tatttgcttt gatttggaaa aaggaacgga caacccttcg
    17221 tttcctacta ggctctctag ctggaactat tggtttaacc ttggccatgt tggttctcaa
    17281 ctatgtttat gctgttcctt tgtacgctaa gtttgctaac tttgatattg gaaaaatttt
    17341 gggactttcc aactacctaa tgaccatggt attacctttt aacttgattg aaggtgttat
    17401 cttttccgtt tcattctggt tgttgtacgt ccttttgaaa ccaaccttaa aacactatga
    17461 aagataaaca aacattttta atgaagggca gttttgccct tttacttttc gttattcttg
    17521 gctatatggt caaattttac cctgaaatgt tggtcaattt tgaccaatcg attcagactg
    17581 ccattcgagg agacttacca gattatttga ctattctttt tcaagccctc acacgtctga
    17641 ttgatatccc agtgattatc acttgggttg tcattacagc ttttgtcttt tatcgtaagc
    17701 gatggaagat agaaagtttc ttcatgctgg gaaatctggc tttggcaggt cttttaatcg
    17761 tgacctttaa aaatatctac cagcgcccac gaccagctat tttacatctg gtggaggaga
    17821 agggattttc cttcccaagt gggcattctc tagctgtaac gctgatggta gggactttga
    17881 ttgttattct tagtcagcgg attaaagatc aggtctggag aaaaatcgaa caaatcgtcc
    17941 ttggcctcta cctagtcagt gtgctggtat caagagtcta tctgggagtt cattacccat
    18001 cagacgtcct tgccagtctc tgtgtgggct tgggagtcct gtttatcgag tttccctttt
    18061 atgacaagct ccgcttccaa tggcgattta aaggcaaaca gaagtgagta tcgaattccc
    18121 ttgagagaaa gaaatgaaag tcaatatagc agatcttcat ccgactcaac tatatttatc
    18181 agaaaagaag ttgcaagata ttcagatgct ttaccagtcg gcagaaacaa tccaagtcga
    18241 tcgaatcagt attcttgcct ttggagattg tttgctgatt acagatgggc atcacagggc
    18301 ttatcaggct ttattggcag gtcgggatac gatttctgct gagtgggata gagatggtgg
    18361 tgatgaacta tatcatctct atgcgcaagc ttgcgaggaa agaaagattt actctgtttt
    18421 tgatttaaaa gatcgtatcc tagctcaaga tgggtatgaa gcaaaatggt ataactggtg
    18481 tgatggtttt aatcaagcag caactctttt gttgaaaagg tagtgcattg tgttttgttc
    18541 cttattataa ggtcaatcat tgtgaggaag cttttgcttg gtatcaggat gtgaacttgg
    18601 tttacctcgt agatggggtg aagcttcctt acagtcaagc gaccttggaa gccatgtatt
    18661 cctatttgga ttggcatggt gagctttttt ggattgaagt caaggagaag ggagaatggt
    18721 ttccaattgg ggatattaca ctatctcagg ataatctccc cattgtgatt gggaattccg
    18781 cttaccaaca tcgaggactt ggaaaaaaga ttctaagtgc tttgattgaa ttggctcgag
    18841 taaaaggatg gaaagaattg agagtcaagg aaatctacac ctacaatcat gcttctagga
    18901 ggtgtttcaa gtcgcttgga tttgtggaaa atggagcaac agaaaaagga aggagtttta
    18961 tattggaatt agtctaatcc tgccactttc tcccccttaa cctttgacta ttccgcaaaa
    19021 ttatcgtaaa ataaagagta aatgataaaa tgaggtcaga gtctgttcgc tctgacaata
    19081 gtagtataaa tgaggagaaa cgctttggaa ttagaagtat ttgctgggca agaaaaaagt
    19141 gaactatcta tgattgaggt agcgcgtgct atcttggaac ttcgtggtcg cgatcatgag
    19201 atgcatttta gcgatcttgt aaacgaaatt caaaactacc ttggaacatc aaacagcgat
    19261 atccgcgaag ctttgccttt gttctacaca gagttgaact ttgacggtag cttcatctca
    19321 cttggggaca acaaatgggg tcttcgttca tggtatggtg tggacgaaat cgacgaagaa
    19381 atcatcgctc ttgaagaaaa tgacgacgat gaagtagcac caaaagctaa gaaaaaacgt
    19441 gtcaatgcct ttatggatgg tgattcagat gccattgact acaatgcaga tgatccagaa
    19501 gacgaagatg catacgaagc agatccagct ctttcatacg atgatgaaaa tccagatgat
    19561 gaaaaaaatg aagtggaagc ttatgatgca gaaatcaacg aaatcgctcc agatgacttg
    19621 ggagaagatg tggatctcaa cgaagacgac gacgagtttt cagatgacga cgctgaaacc
    19681 agcgaggaat aagagttagc tattgacaat tatcctattt ttaggtatca tattgtttgg
    19741 gcacctcttt tagaggtcgg ggctccctag ttcttaggga gctatttttg ttttttcaag
    19801 aagttatctt cttgtatttt atactcaatg aaaatcaaag agcaagctag gaaactagcc
    19861 gtaggctgct caaaacactg ttttgaggtt gtagataaga ctgacaaagt caggaacaca
    19921 tatctacggc aaggcgacgt tgacgcggtt tgaagagatt ttcgaagagt attagttgtg
    19981 aatctggtgc agtcgtccca gattattctt attagtaggg tcttgttttc tatatcccct
    20041 cgtagttaac aagaccttga gcattttaga aagaggaatc tatgtctacg aaatatattt
    20101 ttgtaactgg tggtgtggta tcgtctattg ggaaagggat tgtggcagcg agtctaggcc
    20161 gtctcttgaa aaatcgtggt ctcaaagtaa ccattcaaaa gtttgaccct tatatcaata
    20221 ttgatccggg aaccatgagt ccttaccagc acggggaagt ttttgtgaca gatgacggag
    20281 ctgagacaga tttggacttg ggtcactatg aacgtttcat cgatatcaat ctcaacaaat
    20341 attccaacgt gacaactggg aaaatttaca gtgaagttct tcgtaaagaa cgccgtggag
    20401 aataccttgg ggcaactgtt caagtcattc ctcatatcac agatgctttg aaagaaaaaa
    20461 tcaagcgtgc cgctctaacg accgactctg atgtcattat cacagaggtt ggtggaacag
    20521 taggagatat cgagtccttg ccattcctag aggctcttcg tcagatgaag gcagatgtgg
    20581 gtgcggataa tgtcatgtat atccatacaa ccttgcttcc ttacctcaag gctgctggtg
    20641 aaatgaaaac caaaccaacc caacactctg tcaaagaatt gcgtggcttg ggaatccaac
    20701 caaatatgtt ggttattcgt acagaagagc cagctggtca aggaattaaa aataaactgg
    20761 cccagttctg tgatgtggca ccagaagccg ttatcgaatc gttggatgtt gaacaccttt
    20821 accaaattcc actgaacttg caggcacaag ggatggacca aattgtttgt gatcatttga
    20881 aattagacgc accagcagcg gatatgacag aatggtcagc catggtggac aaggtcatga
    20941 acctcaagaa acaagttaag atttcccttg ttggtaagta tgtggagttg caagatgcct
    21001 atatctcagt ggtcgaagcc ttgaaacact ctggctatgt caatgatgta gaagttaaaa
    21061 tcaattgggt caatgccaat gatgtgacag cagagaatgt agcagaactc ttgtctgatg
    21121 cggacgggat catcgtacca ggtggttttg gtcaacgtgg tacagaaggg aaaatccaag
    21181 ccatccgcta tgcgcgtgaa aatgatgttc caatgttggg agtctgcttg ggaatgcagt
    21241 tgacatgtat cgagtttgct cgtcacgttt taggtcttga aggtgccaat tctgcagagc
    21301 ttgcaccaga aacaaaatac cctatcattg atatcatgcg tgatcagatt gatattgagg
    21361 atatgggtgg aacccttcgt ttgggacttt atccgtctaa gttgaaacgt ggctctaagg
    21421 ctgctgctgc ttatcacaat caagaagtgg tgcaacgccg tcaccgtcac cgttatgagt
    21481 ttaataacgc cttccgtgag cagtttgagg cagcaggctt tgtcttttca ggagtttctc
    21541 cagacaatcg tttggtagaa atcgtggaaa ttcctgaaaa taaattcttt gtagcttgtc
    21601 agtatcaccc tgaactgtca agccgtccaa accgaccaga agaactctac actgcctttg
    21661 ttactgcagc ggttgagaac agcaattagc aaaatcagaa cctttgagaa aaatctcaga
    21721 ggttttttgc atacgatgat attgcagtat atctgaggta ggggtcctct gtatgtacct
    21781 gctaccgttg aaatcaatag cgactccctc ttgccctgtg ctagtgaatg gatttatcag
    21841 tatattgaaa tgaaataaaa tttgaacaaa ttaattcgga aagccaaatc aatttctagc
    21901 aaagttttag gaactggatt gtatagtgaa ttgaaataag atgtgaacat ctctatcaga
    21961 aaagtcaaat taatttatag aaatatttta gcagtcaaga tgtactgtta tagattcaat
    22021 acattatact tttttaattt aattca
//
LOCUS       DAVKBC010000033        20355 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVKBC010000033 DAVKBC010000000
VERSION     DAVKBC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.033"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(95..244)
                     /locus_tag="VWX64_001469"
                     /pseudo
     CDS             complement(95..244)
                     /locus_tag="VWX64_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(398..2029)
                     /gene="rlmD"
                     /locus_tag="VWX64_001470"
     CDS             complement(398..2029)
                     /gene="rlmD"
                     /locus_tag="VWX64_001470"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9190926.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2103..3077)
                     /locus_tag="VWX64_001471"
     CDS             complement(2103..3077)
                     /locus_tag="VWX64_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU9190927.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3151..3765)
                     /gene="pmp23"
                     /locus_tag="VWX64_001472"
     CDS             complement(3151..3765)
                     /gene="pmp23"
                     /locus_tag="VWX64_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU9190928.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3765..4739)
                     /locus_tag="VWX64_001473"
     CDS             complement(3765..4739)
                     /locus_tag="VWX64_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU9190929.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLAYKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4747..6003)
                     /locus_tag="VWX64_001474"
     CDS             complement(4747..6003)
                     /locus_tag="VWX64_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU9190930.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(6065..6496)
                     /locus_tag="VWX64_001475"
     CDS             complement(6065..6496)
                     /locus_tag="VWX64_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190931.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6498..7097)
                     /locus_tag="VWX64_001476"
     CDS             complement(6498..7097)
                     /locus_tag="VWX64_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU9190932.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7084..7923)
                     /gene="prmC"
                     /locus_tag="VWX64_001477"
     CDS             complement(7084..7923)
                     /gene="prmC"
                     /locus_tag="VWX64_001477"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU9190933.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLANENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(7923..9002)
                     /gene="prfA"
                     /locus_tag="VWX64_001478"
     CDS             complement(7923..9002)
                     /gene="prfA"
                     /locus_tag="VWX64_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU9190934.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(8999..9589)
                     /locus_tag="VWX64_001479"
     CDS             complement(8999..9589)
                     /locus_tag="VWX64_001479"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU9190935.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPCCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            9712..9894
                     /locus_tag="VWX64_001480"
     CDS             9712..9894
                     /locus_tag="VWX64_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU9190936.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10031..11404
                     /gene="mnmE"
                     /locus_tag="VWX64_001481"
     CDS             10031..11404
                     /gene="mnmE"
                     /locus_tag="VWX64_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU9190937.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11451..12386)
                     /gene="dapA"
                     /locus_tag="VWX64_001482"
     CDS             complement(11451..12386)
                     /gene="dapA"
                     /locus_tag="VWX64_001482"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU9190938.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDVKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12442..13518)
                     /locus_tag="VWX64_001483"
     CDS             complement(12442..13518)
                     /locus_tag="VWX64_001483"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU9190939.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDSEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(13860..13932)
                     /locus_tag="VWX64_001484"
     tRNA            complement(13860..13932)
                     /locus_tag="VWX64_001484"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13897..13899),aa:Thr,seq:ggt)
     gene            complement(14032..14541)
                     /locus_tag="VWX64_001485"
     CDS             complement(14032..14541)
                     /locus_tag="VWX64_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU9190940.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(14539..14635)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            14664..15095
                     /locus_tag="VWX64_001486"
     CDS             14664..15095
                     /locus_tag="VWX64_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU9190941.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15177..15554
                     /gene="mscL"
                     /locus_tag="VWX64_001487"
     CDS             15177..15554
                     /gene="mscL"
                     /locus_tag="VWX64_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU9190942.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(15596..16690)
                     /gene="hemH"
                     /locus_tag="VWX64_001488"
     CDS             complement(15596..16690)
                     /gene="hemH"
                     /locus_tag="VWX64_001488"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU9190943.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENIKMPYLIKKMLEKAGKLPKE"
     gene            16844..18067
                     /gene="pepT"
                     /locus_tag="VWX64_001489"
     CDS             16844..18067
                     /gene="pepT"
                     /locus_tag="VWX64_001489"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU9190944.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKKVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18103..18435)
                     /locus_tag="VWX64_001490"
     CDS             complement(18103..18435)
                     /locus_tag="VWX64_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190945.1"
                     /translation="MDALLDQLSANSKDKTALLESTKAILVLNHQIQSKASASEETSP
                     ARNAEANGDNTSAENQPNATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTT
                     GNQEKPVE"
     gene            complement(18440..18733)
                     /locus_tag="VWX64_001491"
     CDS             complement(18440..18733)
                     /locus_tag="VWX64_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190946.1"
                     /translation="MSKANQLLERIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHFYLESNNGSDADF"
     gene            18698..18919
                     /locus_tag="VWX64_001492"
     CDS             18698..18919
                     /locus_tag="VWX64_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190947.1"
                     /translation="MDSFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19056..19265)
                     /locus_tag="VWX64_001493"
                     /pseudo
     CDS             complement(19056..19265)
                     /locus_tag="VWX64_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad protein"
     gene            complement(19386..19528)
                     /locus_tag="VWX64_001494"
                     /pseudo
     CDS             complement(19386..19528)
                     /locus_tag="VWX64_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262445.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(19562..19702)
                     /locus_tag="VWX64_001495"
     CDS             complement(19562..19702)
                     /locus_tag="VWX64_001495"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU9190948.1"
                     /translation="MLEITLKSPYQFAHILFQSTIVPHGGHYHFIPESDLSAGELAAA
                     KV"
     gene            complement(19746..20306)
                     /locus_tag="VWX64_001496"
                     /pseudo
     CDS             complement(19746..20306)
                     /locus_tag="VWX64_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         5877 a         4270 c         3838 g         6370 t
ORIGIN      
        1 tatttatttt ttgagtttta aactttggta gaagtcttga actccttata tttacataac
       61 tatttgcctc tataactgtt atgacacgaa accaacaagc aagttcaagc acctccatat
      121 ctttattcaa atgaggacta agatattcac aaactttatc ataaacctct ttatcttttt
      181 tcataaaagg ggcatacaac ttagcaaatt tatcctaaaa ttttttgttg cctttatcaa
      241 tcatttcaac gctcctttaa atataaaaat gatcctatca atctttatat tgagcctatt
      301 ttctaattga taccttgcaa gaaaggaata atagctgttc ctataccaag taggaatgta
      361 ataaatgcag aaagtcatat actgtcattc ttttctatta aatcattttg aagtgtctca
      421 aagcatccat gatggcttct tctttttcag gtgtacactg tggaataatt tgtttatcct
      481 ttttagactt gttgtaatgt tctcgtaatt ctattccaca tttctttttt atctgtgcaa
      541 tatataatgt cgaaactttt aattcaaatt tattccaaac atattctttg atttgagcat
      601 atgttgcttt gctctccgca cttgtcaaat ccatctcatc cagctcaatt tcaacactta
      661 tgtgcttatc gacatcgagt ttggacaaaa gtgctaccgt ctcgacgtga tgcgtttgag
      721 gaaatagatc caccggctgg actttcttca attcatatcc caactcttgg tatagtttaa
      781 tatcacgcgc catggttgcg acattgcagg agatataggc gatgcgatcg gctcctgttt
      841 gggcgcttgc tttgataaag ctttctgtca agcccttgcg tggaggatca accaagataa
      901 cggttggttg aatcccatct ttaagccaat tcttcatagc attttcagct gtgtcacaga
      961 catagtgggc gtttgaaata ttgttcagct gagcattttt tttactattc tcaaccgctt
     1021 ctggaatcag ttcaacaccg tagacttctt tgacatgctt ggcgactgat aaaccaatgg
     1081 ttccaatacc agaataagca tcaataacca catcatcttt ttttaactct gcaaagtcaa
     1141 tggctgtttg atagagtttc tccgccattt cagtattgac ttggtaaaag gctgggccag
     1201 cgatttggaa gtcatttccc aacatctggt ccgtaatata gtcttgacca taaagagtgc
     1261 gccactcctt accaaaaatc gcattggtat tctggtcgtt gatattttgc atgacagaca
     1321 caatctctgg gaactgcttg ataacttgtt caatcaattg gtcaacacga aaaacttttg
     1381 gacgagttgt caccaaaacg accatgattt gtcctgaata gtgaccacga cgcaccacaa
     1441 gattccgaat caatccagac tgttcctttt cgtcataagg ttttaaatca aaacgacgga
     1501 gcaggtctcg aagagctact acgacttggt caatgacagg atcctggata aagaaatctt
     1561 caaggggcat gaggttgtgc gaattcttac ggaaaaatcc tgtttccaag acaccattca
     1621 ctcgacgaac gggcacctgc gccttattgc gatacttgac tggatgttcc ataccaagcg
     1681 tttcagcaac ttctacatct gcaattccag caatcttgta gagactgtcc ttgacttgct
     1741 tggttttaaa cttgagctgt tctggataag aaaggtgtcc taaatccgcg attcctgaac
     1801 gcaggtaagc caaatctaga tcttgattac ggtgtggtga ctggacaagg tatttttcaa
     1861 cttttccaaa gccaatcttt ttattgacct tgaggacacg catgagaatt ttttcactcg
     1921 gtaaagcatt ctctacaaaa aagaccaaac catctacctt ggcaactcct gccccttcat
     1981 gggtcaaatc aacaatttca acttctacaa tatcattttt ctttaacatt cttttctctt
     2041 tctattggcc gacaaaaaag acggcaacgt tacggttacc atccattata ccatgaaatt
     2101 tcttaagaac caaaactctt gaagaagttg acaagggctt gccagaggga gcttaagaag
     2161 ttaccaccgt cctctagcgc cttatccgca tcaaagttaa ggttgatatt tttaaaactg
     2221 tcgccagctt gtgatacgat gctttgttta aggtcattta aggttttagt gaaatctgca
     2281 ttgctgagga tatcactctt tgagagattc aaggcaaaat tgatgatgat attgatctgg
     2341 tttcctgtta tgacctgatc aagtttgtaa ttttttaagg tatcttcaac aatcttgcgg
     2401 atatcttctt ctgtcagatt tcccttgctt tctttagctt tggcgagtcc tgacttgata
     2461 tcagctaggg caacgtttaa tttattagca tcatagcctg atttgtcctt gttttcagca
     2521 ttgatatctg acaaagcctt tagctcttct tgagccaaat ctttattggc ttgcggcacc
     2581 ttggctccat tagcttctag cgaatagtag atcccagcca aagcactctc acctgtaact
     2641 ggaatgggtg ctgctacagt gattttggcg tgttccacac ccaaagttac ggctgcattt
     2701 cggtacatat cctgagttac cttagtgatg ttttcaggtg tttcaatctt gacctcaagt
     2761 ggcgatttgt cacctagctt ttgaatcttg gctgatgaat acaactgtaa gctagagtca
     2821 ttggccacat tcatgatttt agaataaaca tcaggtgtca tggtcttgag ttctttggta
     2881 tctgttgagg cattgtagcc cagtttttta agagtttgat ttttttggtc ttcagatagg
     2941 gaagaaccta ggacatattc aggttggaca taggtttcat cgataacttt ttgaacatct
     3001 gttgctgcat ggacgctatt catagctgtt actgcccaca agatcgcagc gctagtcaga
     3061 aagagtttct ttctcatagg gaatttcctc ctttacttct ttagagtaat atatctatct
     3121 taaagaaaac ttataacaaa aacacctggt ctagccagat gttgaaaaga gagtgaaaca
     3181 tttgatgatg taaaggttaa gtcgtacctg tctagaataa taatagtttc ctccatttac
     3241 atagagttca gcaccgtgaa aaatggaaat ggggtgaata taactataag tctttccagt
     3301 cctattacca agcaaggggg caacagtctc acgagagtac tgtttggcta gagccaaggt
     3361 attttccttg ccattttggg cgataaaatc gatataggca ggtccaaaat tataggcttg
     3421 aacagctgtc cagatatcta cacccttctt ctgcgccaga tagagattgc ctgtcagagt
     3481 ttgaatgcct tgccgaatgc tagaggcatt atcattgatg gtgttggtgg aaccacttgc
     3541 agactcacta gactgcataa catcgccttc ttttcctttt gtttcagtat aaatcatagc
     3601 aagcacaagc tcttcgtttg ctggggtgtc tttttcactc aatatttctc gcaccatggg
     3661 ttgataggtc atgacttgtt tgacatcttg atgaacgcgg taagctttat agccagcaaa
     3721 aaggaagact gctagtacaa gcactcttcg aattcgttta aacattattt actttggata
     3781 tcctcgatat ttttgattaa gatagagtag gttccatttt cgttttggat aaactcaaca
     3841 gactcggcgt cttgatagac gttattggga acgatgagct caattccatt tgataaggag
     3901 agtttttggt tttcaaattt ctttaattgg cgactggcat caatttcatc aaattgaaca
     3961 ggttctggta cggcttcttt gacttggtca ataaagctca aacgagccgt cagattgttg
     4021 tcaaaaaggt cattagccaa tttctcaggt gacaattcat tgctttcttc taggttgttg
     4081 aaaatagctg atttgacctt ggattgaaat tgaaaatcat ctgtgttaaa agattcagca
     4141 attctctggg ctgttttttc cagttccttg atagattttt taggagaaat cttaggagcg
     4201 acagcaagaa gattatctga aaaatagttc aaaaaagtcc cgttgtactt gattcgtttt
     4261 tcaatcaggt gatacttgcg actctgaaga ttgaccacca aggcctcgtc agcacccgtt
     4321 ccaaatccag gcaggttatt ctgagtcagc ttgattggat tatcaacttc tcctccgagg
     4381 tgggtcaagg tctcccgcag ggcaattcgc aagaaagcga aatgttctac accttcttta
     4441 gaaaattgaa caaaaatcaa gtcattggtc ttgagatttt cagaaatgct aaactcctct
     4501 ttccagagat tagccagcgt tactgatgtc tccaacaaat cgtctgtaat atgattgaag
     4561 aagggatttt cttcttcgaa aatcccagtc ttggcttcat ctgaatacac atgttcaatt
     4621 tttttacgta ggtattcttc gatttttgga gtaatattga gaaacttata tgctaagaac
     4681 agctcggtat catccggact gaactggtga ataatggctt tcttaatata aatgtccata
     4741 aaagttttag tcctcgtata atgggaaggc atctgtcaat tctttgactg cacttctcac
     4801 ttcttctaat acagcctcat tttctgaatt cttaagggtt ttaatgatga gttcagccac
     4861 tttgcgactt tcttcttcac caaatccacg tgcagtaata gctgctgctc cgatacgaat
     4921 cccacttgtc ttgaatggcg acaaggtttc gtaagggatt gaatttttat ttagggtaat
     4981 attgacttca tccagcaagt tttgagcaac ttttccgttt tctacaacct tagtcacatc
     5041 aacaaggaag agatggtttt cagttccacc tgaaataata cggaaatcag ggtcttgcaa
     5101 gaagacatct gccatagcct tgctgttctt aattacattg gcagcatatt ccttgaaggc
     5161 tggatccaaa acttctttga aggaaactgc cttagccgcc acaacatgct ctaaaggacc
     5221 gccctgaata cctgggaaaa tagctgaatt gattttttta gcaagttctt cgtcattggt
     5281 caaaatcaaa ccaccacgag gtccacgaag ggttttgtgg gtcgttgttg ttgtgatatg
     5341 agcgtatgga actgggcttg gatgaaggcc agccgcaacc aaaccagcga tatgggccat
     5401 gtccaccatg agcttcgcac cgacagcatc tgcgatttca cggaattttg aaaaatcgat
     5461 aatttgagaa tatgctgaag caccagctac aatcagtttt ggttttactt cttgggcttg
     5521 tttcaagata gcatcaaagt ctaagagttc cgtttcagga tcaacactat aagaaacaaa
     5581 gttgtaggtt tgaccagaga agctaacagg agccccatga gtcaaatgac cacctgatgc
     5641 caaatccatt cccataaccg tatcacctgg ctcaatcaag gacatgtaag ccgcacagtt
     5701 agcttggctt cctgaatgtg gttggacatt ggcaaattta gcaccgaaaa tttcttttgc
     5761 gcgttcaata gcaagagtct ctacaacgtc tactacatca gttccaccat aataacggcg
     5821 tcctgggtaa ccctcggcat atttatttgt caagatagac ccttgagctg ccataacagc
     5881 cttggaaact acgttttccg aagcaattaa ctcgatatta ttttgttggc gttcttcttc
     5941 tttggcaata gcattccaga gatcagcatc atatgcttta aaatcatctt tgtcaaaaat
     6001 cataggtctt ctcctttatt gtgtgactag tccattagtt tgattttaca ataagaaaat
     6061 caaactaaaa gatgcgaata aaccgtttct gcattttatc acaagtatag ccaacttttt
     6121 cataaaatgc atgagcaccc agacgatgat tggcagaatt taagcggata aacccataac
     6181 cacatctttt ggcttcttgt tccaaccctt gtagtaaact tttaccgata ccttgacctt
     6241 gcgcttgagg tgaaactgct aaagctaaga tattaaatcc tgctttggaa tagagtgatt
     6301 cgtaaacttc agcgtggaca tatccaagta agacatgatt agctgcatcc tcatagccaa
     6361 gtaggaaatg atgggaatcc tgagacagtc tagctagttg gctagccgtt tcctctggac
     6421 taaaagtata acccaaagcc tcttggttga tgtcacatat cgctttcaca tctgtttctt
     6481 gcaaatctct tagcatttca agcctcctca aaagaaatct ctggcaaccg agcaagaata
     6541 tcttctcgtt taattgcgcc ttggcgtaag attttcacct tgtctccaga caaatccaca
     6601 atagttgaat cctgtccagt tagaaaagca tcgtcttcca gacccagaac ctcttggtca
     6661 aaatccttca gaatttgttc aaaggttaca ccacttgcct gacctgagat attggcagac
     6721 ggcccaatca agggacctgt ctctcgaatt aaatccagtg tgatagggtg actgggcatc
     6781 cgaaatccaa tagttgcaag gtcagaattt acccaatagg gaactcggtc attggcttcg
     6841 agaataatgg tcaagggacc tggcaaaaag gtctctacaa gtttttgtag ataagctggc
     6901 tgattcttag aaaagtgcaa gatatcctct aaagaggcaa cattgagatt gagcgccttg
     6961 tctctaggac gacgtttgag ctggtaaaca tggtcaactg ctttttcgtc taaggccttg
     7021 gcaaaaagac cataaaccgt ctctgtaggc agaatgacag ctccaccatt ttccaactct
     7081 tgtctaatcc tgtccatcat caaccacgac catcctatct tgaccaaatt ggtccttgag
     7141 tgttcgaact tttttttcag gaagatgttt tctaaaaagt tcgggaacac tttgaccttg
     7201 cttgtatcca atttcaaggt aaatcttacc accatctttg agatagtctt ttgcatcttc
     7261 cgcaattcta cggtaaatag ctaggccatc ctcgtctgca aagagagcta gatgaggctc
     7321 cgaatacaag acattcaagc ctacctctga ctcatcttca cgagagatat agggtggatt
     7381 ggaaacaatt atatcatatt tttcagaaat ttctgtaaaa cagtcagatt ttttaaaaaa
     7441 tatttgaaga ttttgatttt tagcattttc gttagctaaa tctaaagcct cttgagaaac
     7501 atctgctgct gtcactgacc aatctggtct attttttgct agagcgagag caatagctcc
     7561 actacctgtt ccaatatcca gaactgaaag attcgtctca agattttcag ttagaataag
     7621 ctccactaac tcctctgttt ctggacgagg aatcaaaacc cgttcatcca cctttaaatg
     7681 cattccataa aaatctgcct gtccaatgat gtactgagct ggcttgtgag ctgctagttg
     7741 ctggtaaata tcttctacaa attgtttttc ttcctctgtt gtcacctcct gctggagggc
     7801 aaaaataaag tctgtaaaag atagattttt cagactacga tagacaaaag agaggctttc
     7861 cgcttcctct ccttgtctta tcaactcttc ttcaaaattt gaaaataatt gagctaattt
     7921 cattatttgt ttaattcttc tagtttttgt gtttggtcat aaagcaccaa ggcatccaca
     7981 acttcgtcca atttaccaga caaaatcgta tctagttttt ggagggtcaa gccgatacgg
     8041 tggtctgtga cacggttttg tgggaagtta taagttcgga tccgttctga acggtcacca
     8101 gtaccgattg tcgacttacg ctcagcgtct tgttcatcct gagcaatctg agcaaagtgg
     8161 tcagcgacgc gtgcacggat aatcttcata gccttctcgc ggttcttctg ctgggtacgt
     8221 tcttcctgca tctcaacctt gatattggtt ggcaagtgaa cgatacgaac ggcagtcgca
     8281 accttattga cgttctgtcc accagcacca gaggcgtgat agatgtcgac acgaaggtct
     8341 tttggatcaa tgtcgtattc aacctcttca acttctggca taacaagaac tgtcgctgtc
     8401 gaagtatgaa cacggccttg gctttctgtc acaggaacac gttgcacacg gtgggcacct
     8461 gattcatact taagcttaga gtatacagac tgacctgaaa ccatagcaac cacttcttta
     8521 aaaccaccga caccattcat agaggcttcc atgacttcaa agcgccaacc ttgggcttcc
     8581 gcatactttt ggtacatagt tagcaaatct ccagcgaaaa gtgccgcttc gtctccacca
     8641 gctgctccac ggatttcaag gatgatattc ttgtcatcgt ttggatcctt tggaaggagc
     8701 aaaattttca gtttttcttc atattcttct ttttcagcct tggcatcttt gagttcttgc
     8761 ttggccaatt cttccaagtc cgcatctccg cctgattcct taatcatctc ttcggcatcg
     8821 acgatatttt gaaggacttg tttatactca cggtaggcta ttacggtgtc acgatttgaa
     8881 gcttcttctt ttgaaagctc cataaaacgc ttggtgtctg aaacgacatc agggtcactc
     8941 agcaattctc ctagttcttc ataacggtct tctacagctt gtagttgatc atagatgttc
     9001 atttttcttc attctcctta ttgatttcag gggcaaaata atgtttacgg caaaccgaga
     9061 tataggtttc attaccacca atctggatct gttctccatc gtaaacgggc agtccatcct
     9121 gtgttcgcaa caccatggtc gcctttttct tgcaatactg acagatggtc ttgatttcgt
     9181 caatcttgtc cgctaaaagc aagagatatt tggaaccttc gaacaattca ttgcgaaagt
     9241 catttttcaa gccaaaagcc atgacgggta tgtctaactc gtccacaaca cgagctaggt
     9301 cgtaaacatg gtggcgttta agaaactggg cttcatcgac caaaacacag caaggttttt
     9361 ctggtaggtc tcggatatag ccaaagatat ccgttgtttc ctcaatcgca agggcagggc
     9421 gtttcatgcc aattcgactc gacacatagc caacaccgtc acgcgtatcc agagccgagg
     9481 tcataatgac aacacctttt ccttgctcct cgtagttata ggccactttg agaatctcaa
     9541 tcgttttacc agagttcatg gtcccataac gatagtacaa ctgtgccatg tttcttgctt
     9601 cacgtccatt tctaaatttt tgctacattc tagtatatca taattttctt aagctttaaa
     9661 cggcaaaatg tggtaaaatg gaagaaatca aaactagtgg aggaagctat tatgccattt
     9721 gtacgcatcg atttatttga aggacgcacg ctcgagcaaa agaaagctct tgctaaggaa
     9781 gtaacggaag cagttgtccg caacactgga gcccctcaat ctgctgtcca tgtcatcatc
     9841 aacgacatgc cagaaggaac ttacttccca caaggggaaa tgcgtactaa ataagctagc
     9901 ttaagcagaa ttgcttaggc tttttcaatc tccaagtagc attcattgaa gaaatatcct
     9961 aaatttgtta caatttgaaa agaaacttgg agaatttcca agaaaagagc tattaattaa
    10021 aggaaacatt atgattacac gtgaatttga taccatcgct gctatctcta ctccactagg
    10081 tgaaggagct attggtattg tccgcctgag cggaacagac agttttgcta ttgcgcaaaa
    10141 gatttttaaa ggaaaagact tgaacaaggt tgccagccac actctcaact acggtcacat
    10201 tattgatcct ctgactggta aagtcatgga cgaggttatg gttggggcta tgaagtctcc
    10261 aaagaccttc actcgtgagg atattatcga gattaacacc cacggtggga ttgcggtgac
    10321 caatgaaatt ctccagctag ctattcgtga aggggctcgg ttggcagaac ctggtgaatt
    10381 taccaaacgt gcttttttaa acggtcgcgt agacttgaca caggcagagg ctgtgatgga
    10441 tatcatccgt gccaagactg acaaggccat gaacattgcg gtcaaacaat tagacggctc
    10501 cctttctgac ctcattaaca atacccgtca agaaatcctc aatacacttg cccaagttga
    10561 ggtcaatatc gactatcctg aatatgatga tgttgaggaa gctactactg ccgttgtccg
    10621 tgagaagact atggagtttg agcaattgct aaccaagctc cttaggacag cacgtcgtgg
    10681 taaaatcctt cgtgaaggaa tttcaacggc tatcattgga cgtcccaacg ttgggaaatc
    10741 aagccttctc aacaacctct tgcgtgagga caaggctatc gtaaccgata tcgctgggac
    10801 aacacgagat gtcatcgaag agtacgtcaa catcaatggt gttcctctaa aattgattga
    10861 cacagctggt attcgtgaaa cggatgatat cgttgaacaa atcggtgttg agcgttcgaa
    10921 aaaagccctc aaggaagccg acttggttct actagtgcta aatgccagtg aaccactgac
    10981 tgcgcaagac agacaacttc ttgaaattag ccaagatacc aatcgcatta ttctacttaa
    11041 taaaaccgac ctgccagaaa cgattgaaac ttcgaaacta cctgaagacg ttatccgtat
    11101 ttcagtcctt aaaaaccaaa acatcgacaa gattgaagag cgaatcaaca acctcttctt
    11161 tgaaaatgct ggcttggtcg agcaagatgc tacttacttg tcaaacgccc gtcacatttc
    11221 cctgattgaa aaagcagttg aaagcctaca agccgttaat caaggtcttg agctggggat
    11281 gccagttgat ttgcttcaag ttgacttgac tcgtacttgg gaaatcctcg gagaaatcac
    11341 tggggatgct gctccagatg aactcatcac ccaactcttt agccaattct gtttaggaaa
    11401 ataagaaaaa tccatgatcc ttcattcggt catggatttt attgtcttta ttagtaatct
    11461 ggtcttaaga cccctgttac agttgcctta gttgcttcgt agtcgccatc tacgacaacc
    11521 ttgataatgc gtttgacatc ttcttctggt gctggaacaa gaggtagacg agtgggtcca
    11581 gcttcaaatc ccatatagtt aagaattgcc ttaactggag caggacttgg ataagagaag
    11641 agagcattaa ccttaggaat gaatttacgc tgaattgctg cggctttctt catatcgctt
    11701 tctgcaatgg cagtaaacat ctcgtgcatt tcatccccat ttgtatgaga ggcaacagaa
    11761 ataaccccat ccgccccaag gttcatggca tggaaagcat ctccatcctc acctgtataa
    11821 atcaagaact cttcaggctt gtgctcaatc aagtaagcca tattagccaa gctagtacat
    11881 tctttgacac cgataatatt tggatggtca gccaagcgaa gcatggtttc tggagtcaat
    11941 tcgacaacta cacgccctgg aatgttatag ataataattg gtaggtcaga agcatctgca
    12001 atagccttaa agtgctgata catcccttct tgagaaggtt tgttgtagta aggaacaata
    12061 gcaagcccag ctgcgaaacc accaaattcc gctacttctt tgacaaactc aatagagtca
    12121 cgcgtatcat tagtacctac acccgcaatc aaaggaacgc gtccattgac aaccttttgt
    12181 acagccgcaa acaactccaa ctcctcatcg tgggtcaaag ttggactctc agcagtcgtt
    12241 cctgcgagaa gaattccatc cgtatgatgg gccaataaat gctcaatcaa ggctggaata
    12301 gcatcaaagt taatggaacc atcctcatgg aagggggtaa taaaggctgt aatgatttta
    12361 cattctttta aatcttgata agacacgaaa acacctctct atttcaaaga aggagttcat
    12421 ctgaactcct aaacgatatg actattttaa ttcaaatttc aattcggctg ttggacgaac
    12481 caatccacgt tcatgaagag tttcagcaat ctgaactgag ttccaagcag cacctttgag
    12541 aaggttatct gaaacaaccc acatgtgaat tcctttttct gaatccaagt ctttacggat
    12601 acgaccaaca aaggtatcac gcgaaccaac tgcattgata gcttgaggat agatttgatg
    12661 agctacatca tcttcaagaa cagcacctgg gaaggctgcg atagctgctt ttacttcttc
    12721 gattggagcc acttcttttg tttcgatata aacagactca gagtgagctg acaagactgg
    12781 aatacgcaca catgttgcag atactgcaat gctatcatct tccataattt tcttagtttc
    12841 cttggtcatc ttcatctctt cgtacgtgta atcattatca gtgaaaacat caatttgtgg
    12901 aagagcgtta aaggcgatag gataatgttt cttgtcacca cctgaaggca agatttccgc
    12961 atgcaaatca cgtggtttca caccatcatt caagacttca cgaagttcac gttgtgtctc
    13021 aagaattgct cccataccag cacctgaaac ggcttgataa gttgaaacaa tgatacggtc
    13081 caagccccat ttttggcgaa ccggctcaag agccaccatc atttggattg ttgaacaatt
    13141 agggcaggca atgattccgt tgtgagcatc aagtgcatga gcattgacct ctggaacaac
    13201 caaaggaaca tctggatttt gacggaaata agatgtatta tctactacta ccacgccagc
    13261 ttttactgcg tatggtgcat acttagctga tgtagaacta cctgctgaaa agagagcaat
    13321 atcaactcct tcaaaagctg tttcagtcgt ttcttcaatt gtaatatctt gatctttaaa
    13381 tttcaatgac ttacctgctg aacgtgcaga agcaaggtaa cgaattttat cgattggaag
    13441 tgttgattct tccaacattt ttatcatctg agcaccgaca gcacctgtcg cgccgactac
    13501 agcaactgta tatcccataa ataacctctt tcggaatttt ctaaaaattt ctataataga
    13561 agtattatac tactttttcc atgaattgca aagctttttc atcatttttt ggaaaataaa
    13621 aatcccagtc gctagactag ggactaagag gcatcttcat gtgatgagca ggttcacaca
    13681 actcatcaag gtccgctcct gcgttatgac ctccttatgc tcaatagtag tccgaagact
    13741 acctatcgac tcatcgcata ttctatatta ctagagatac ttgattttgt caataagaaa
    13801 ttttttcgat cgagtataac aaaaaactct catattcaag agtttcccta tacatatcat
    13861 gctaattgcc gggattgaac cggcgacctc atccttacca tggatgcgct ctgccaactg
    13921 agctaaatca gcttacttaa gaagtatact atattcagaa aaacttgtca agtttcctta
    13981 gaaattttcc ataggaaaaa gccaggtaag aactacctag cttatcttct tctatttact
    14041 taaatcaatt cgacgaccaa ttttaccaat aataatcgcc ccaataatca atgaagcaaa
    14101 ttcaccgatt cctgttgtaa accaagtaag gaagaatggt aattctgcta caatatttaa
    14161 ctctgcagcg atagtaaaca tggaaattga aaagaggatt gaaaagaaga aatgatcttt
    14221 tcgaatcaat ccgttaaaga ggtaatcctt gctatatttt gcaaaaagcc aaacacctaa
    14281 actgaggaat actaaggttg aaccaccacc aacaaagaca tctagcagtc cgaagctaaa
    14341 gaaattagca atcatacaac cgatggtaac tccgatgatg tacttaggat tgtaaaaagc
    14401 cataaagttc atcatttctg aaatacgaaa ctgataagca ccatagctga tggcatttag
    14461 gggcggtgtg acagtcaaaa cgacgtagat agcagcgacg attgcaatat ctgcaacatc
    14521 acgaatagtt aattttttca tcttttctcc tttggcggtt atccgcgtgt aatatgcttg
    14581 gtgaaagaag ctaagcacca agggttgatt cattcaacct tactagtata gcacaatagc
    14641 ctgctttatg ctatacttaa agcatgaaaa aacctattca aaaatttttt aacaatgaaa
    14701 tcttagccta tctctttttt ggccttgcga caactctagt ttcgattctc tcacgactag
    14761 tcatttatca actaagtcat caggaactcc ttgctacggc cttggcaaat attatcggta
    14821 tcttatttgc ctttatcaca aatgatacga ttgtatttaa gcaaaaaaag aaaaatagac
    14881 ttatccgttt agtgaaattt tctcttgctc gcctttctac ttttctgtta gacttgtttt
    14941 taacttttct ctttgtaacc caatttcctc acatcatagg gcaattcgta actgaaaaca
    15001 ttgataagat aaatgctatt gaaacaataa ttgcacaaat attcattatt atcatcaatt
    15061 atatattgag caaggtctat atttttagaa aataatgctc catttatgag ccttttaatt
    15121 gccttctata atgatttagg atacaatgaa acacgaaaca ttgaaaggaa aacagtatgt
    15181 taaaaaatct aaaatcgttc ttgcttcgag gaaatgttat tgaccttgct gtcggtgttg
    15241 tcattgcctc tgcttttggt gctatcgtta cttcacttgt aaacgacatt atcactcctc
    15301 ttattttaaa tcccgctttg aaagctgcta aagtcgaacg tatcgctcaa ctttcttggc
    15361 atggagtcgg ctatggtaac tttttaagtg ctattatcaa ttttatcttt gtgggtaccg
    15421 ccctcttctt tattatcaag ggcattgaaa aagcacagaa actgactggc ataaagaaag
    15481 aaaaaactgc cgaaaaaaaa ccaaccgaat tggaagtcct tcaagaaata aaagctctcc
    15541 ttgagaaaaa ataatcgatt aaaaggatct agcgcaaagc taaatccttt tttctttact
    15601 ctttgggtaa cttgcctgct ttttcaagca tttttttgat aagataaggc atcttaatat
    15661 tctcccgccc ttttttctca atcagttttt tcacaaattc tggcatttgt aaatcttcag
    15721 attcagctaa aatgtttttc gtctcgtctg aaggaactaa ctcatcaaag gtctcttctt
    15781 ctgggagaaa ttccttaaac tcttgatttt cattgactct aactgtattg accaaagcat
    15841 caatcaaacg agaatctgta tttggcattg gtggacgatg gtagtttacc ccaaattcct
    15901 gacataaatc ataacattcc acatcattgt caaacaagac ctcaatatgc tcactgatga
    15961 aactaatagg tacaaaaata taatggtctg gatgttctgt ctgttctctg agatactcca
    16021 aaacatctgg tttaatccat ggaataccaa tatcactctc actctgccaa gtgttggtat
    16081 attgttctga actcaagccc agtttttcag cgactagctt gctattttcg aaaatttggt
    16141 ctatataagg atctccaaag tccaaggcaa aaataggcac actatgggct gaaaagatga
    16201 ctttaaagct gtcttgcttt acttcttctt ttaaaatctt agcaatttca tctgcccaat
    16261 agtttaagag cgcttcttcc tgataccagt ccttaatgac caaaaattga atttgtttgc
    16321 tttctaaaaa tttttcatag cccatgacag agtagaaaga atagtggggc tccaaaatca
    16381 agcaaataca ctgttcaatt ccgtctgctt ccatttgacc gatcacatct ggaataaagg
    16441 gactggaaaa cttattagca aagtagacac tgtattcatt ccccagccta gcttctacca
    16501 aggcaacctc ttgacgggta attttttgca gaggcgtgcc tccaattcgt acataattat
    16561 catagagagt ctgaatctcg tggtcttggg gtctcatccc acgacgaata tttgtgaaaa
    16621 aatcagctac accttcaaag gtaatctctt ctggtgaacc gaaggtcatc attaaaattg
    16681 cttttttcat gactgcttcc ttgtgatgtt tttatcaagt ttattttatc attaattcat
    16741 cgataagtaa acgctagcat agggacattc tcaatcttct gtcttttgtt tttctcttct
    16801 ttctatgata caatggaaaa aataaattca aaaggagttt tttatgactt atccaaatct
    16861 cttggaccgc ttcttaacct acgttaaggt caacacgcgc tctgatgaac actctactac
    16921 tactccaagt acacagagtc aggttgactt cgcaacaaat gtcctaattc ctgaaatgaa
    16981 acgtgttgga ctgcaaaatg tttactatct accgaatggt tttgctattg gaaccttgcc
    17041 agccaacgat ccgtctttaa cacgtaagat tggttttata tcgcacatgg atactgctga
    17101 ttttaatgct gaaggagtca atccacaggt aattgaaaac tacgatggtg gtgtgattga
    17161 actagggaat tctggtttca aactcgatcc agccgacttc aagagtcttg aaaaatatcc
    17221 aggacaaacg ctcatcacaa cagatggaac aaccttgcta ggtgctgatg acaagtcagg
    17281 aattgctgaa attatgacag ccattgaata tctaactgct catcctgaaa ttaagcactg
    17341 tgagattcgt gttggttttg gtccagatga agaaatcggt gttggtgcca ataaatttga
    17401 tgcagaagat tttgatgtgg attttgccta cactgttgat ggtggtccac taggtgaact
    17461 tcagtacgag actttctcag ccgctggtgc tgaattgcat ttccaaggcc gtaatgtcca
    17521 ccctggtact gccaaagggc agatggtcaa tgcccttcag ctagcaattg attttcataa
    17581 tcaacttcca gaaaatgacc gacctgagtt aactgaaggt taccaaggtt tttaccatct
    17641 aatggatgtg acaggtagtg ttgaggaggc gcgtgcaagc tacatcattc gtgattttga
    17701 aaaagatgcc tttgaagcgc gtaaagcatc catgcaatct atcgctgata agatgaatga
    17761 agaacttggg agcaaccgtg tcactctcaa cttgacagac cagtactaca atatgaaaaa
    17821 agtcattgaa aaagatatga ctccaattac cattgctaaa gccgttatgg aagatctagg
    17881 tatcacgcct attatcgaac caatccgggg tggaacagac ggctctaaga tttcctttat
    17941 gggaatccca actccgaata tctttgcagg tggcgaaaat atgcacggac gttttgaata
    18001 cgttagcctt cagactatgg aacgtgcagt tgataccatc attggcatcg tagcttataa
    18061 aggctaaaaa gacgaggtag ctcagctact tcgcctttct ttttattcta ctggtttttc
    18121 ttgatttcca gtagttgtag aagattctgt tgttttattt tctgaagttg attcagcagg
    18181 tttagaatct cttgtattgc ttggtttgtt ttcgtcgcta gcagtttcaa tgttagattc
    18241 tgcagttgcg tttggttggt tctcagcact ggtgttatca ccatttgctt cagcatttct
    18301 tgctggactt gtttcttcac ttgcgctagc ttttgactgg atttgatgat tcaaaactag
    18361 aatagctttt gtcgattcaa gtaaagctgt tttgtcttta ctattagcag aaagttgatc
    18421 taataatgca tccaccttat caaaagtccg catcagatcc attattactt tctaaataaa
    18481 agtgaagcga catgagaata tcgtagagtt tttgatagag tacaagtgtc tgaggatctt
    18541 gctcagcatt ttccttttct tgttgaaggg cgctagcgat acgagtcaag acatctttta
    18601 cctgactgtt tacttcatcc aagtctgcat cagccttgtt tgtggcagct tttagatttt
    18661 ctacttcttc tgccaaagat tgtctgattc cttcttcatg gattcgttcc aagagttgat
    18721 ttgccttgct caaaagactt tctacttctt ccttgctatc tgtcgcagat tattggttgc
    18781 tatctaccat gtactcctaa aacaggagag ttataatcca agattacaag gccttacaga
    18841 aataagaaat ccagataaga caatgttcgt ccaagacgct attcgcttcg cacagcagca
    18901 cggattcaat atgctttaat tttaaagttt aggtgtcaag acctcttttt agtgtgccca
    18961 aaatttagag aagtaatcaa tcaactaact tttatttttt tcaaactttc agtaaactga
    19021 cctaaagcta actcaatctg tctttgttcg ataggcttgt ctttgtagat gcttctgcta
    19081 tcagctagaa gttgatctac ttttgccaag actgccttct catcaaaagt tccaggttga
    19141 tagttggatt gcagggatgg aatcttgttt ttcaaagccg cttcatatcc cttagtttga
    19201 accttgatgt agtgattgtg gtcgccacga ggaatcacaa aaccttctga atcttcactt
    19261 ataattcgat tggcatcaaa accatgacca tcttcttcct catggtggac atgtagtgac
    19321 ggattactta atacagaact agaagaactt cctacctttt ccgtgttaga gtgtgatggg
    19381 ggattgttaa gagatgactt aggaatatag tgatagtgac cccatgtctt actatataag
    19441 catcacctgt atctctgaca atatcattag ggttaaagac ataaccatca tctgctgcag
    19501 aaacaccatt attcggtgtc accgacaaag attgactgag agctgtagta ttctctgata
    19561 attatacttt tgcagctgct aattcacctg ccgacaagtc actctcagga atgaaatgat
    19621 agtgaccacc atgtggtact atagtagatt gaaatagaat atgagcaaat tgataagggg
    19681 attttaaagt aatttctaac aatgatttag aaactatgat gtgctattct aaattcaact
    19741 cactatatat aaccatcatc ggtagtataa cgtccctgta attttgctac agatacttct
    19801 gcactagctc ctttatcgtc tttaccatgt tcttgttttt ggcgattgat ttcatctttt
    19861 attcgtacat tttctgcatg agcttgatct ttaaggtaaa cataatactt tccatctacc
    19921 ttaataatat atcctccctt aacctaactg acgatatctt gatctttcgg ctgatagttg
    19981 ggggctttca ttaatagctc ttcactaaag agcgcatcca aaggaacttt accattatag
    20041 cagtgataat gatcgccatg agaagttaca taaccttgat ctgtaatctt aataacaatt
    20101 tgttttgctt gaattccttc tttttgacta acctagtctg gagtcaaatt ttcagtcttc
    20161 ttagtgtctt tattactgtt tacatatgaa acacgatttt tatctgtatt ggcctgttag
    20221 ctatgttggt tcagagcata aacacacaga cttaaggaaa ggataacaac agatccagct
    20281 gctatatatt tctttttaaa tttcataatt acctcatttc tataattatt tatatgatgt
    20341 cttcattatt aaatg
//
LOCUS       DAVKBC010000034        20039 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVKBC010000034 DAVKBC010000000
VERSION     DAVKBC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.034"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            122..3223
                     /locus_tag="VWX64_001497"
     CDS             122..3223
                     /locus_tag="VWX64_001497"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU9190949.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDISLKLPRFNPARPAVEELRERAELGFVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKSEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3306..4313
                     /gene="pfkA"
                     /locus_tag="VWX64_001498"
     CDS             3306..4313
                     /gene="pfkA"
                     /locus_tag="VWX64_001498"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU9190950.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPRKADIELSSLNKSL
                     S"
     gene            4372..5877
                     /gene="pyk"
                     /locus_tag="VWX64_001499"
     CDS             4372..5877
                     /gene="pyk"
                     /locus_tag="VWX64_001499"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU9190951.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6561..6786)
                     /locus_tag="VWX64_001500"
                     /pseudo
     CDS             complement(6561..6786)
                     /locus_tag="VWX64_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7634..8506
                     /locus_tag="VWX64_001501"
     CDS             7634..8506
                     /locus_tag="VWX64_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU9190952.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8652..8996)
                     /locus_tag="VWX64_001502"
                     /pseudo
     CDS             complement(8652..8996)
                     /locus_tag="VWX64_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9139..9450
                     /locus_tag="VWX64_001503"
     CDS             9139..9450
                     /locus_tag="VWX64_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190953.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNVSDKETAEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9454..10170
                     /locus_tag="VWX64_001504"
     CDS             9454..10170
                     /locus_tag="VWX64_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9190954.1"
                     /translation="MKKYFIGCLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10300..11115)
                     /locus_tag="VWX64_001505"
     CDS             complement(10300..11115)
                     /locus_tag="VWX64_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU9190955.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11112..12017)
                     /locus_tag="VWX64_001506"
     CDS             complement(11112..12017)
                     /locus_tag="VWX64_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU9190956.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIISGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            complement(12347..12430)
                     /locus_tag="VWX64_001507"
                     /pseudo
     CDS             complement(12347..12430)
                     /locus_tag="VWX64_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            12474..14603
                     /locus_tag="VWX64_001508"
     CDS             12474..14603
                     /locus_tag="VWX64_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU9190957.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            14590..15039
                     /locus_tag="VWX64_001509"
     CDS             14590..15039
                     /locus_tag="VWX64_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU9190958.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            15098..15370
                     /locus_tag="VWX64_001510"
     CDS             15098..15370
                     /locus_tag="VWX64_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9190959.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(15724..15915)
                     /locus_tag="VWX64_001511"
     CDS             complement(15724..15915)
                     /locus_tag="VWX64_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190960.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            16343..17101
                     /locus_tag="VWX64_001512"
     CDS             16343..17101
                     /locus_tag="VWX64_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9190961.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            17103..19091
                     /locus_tag="VWX64_001513"
     CDS             17103..19091
                     /locus_tag="VWX64_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9190962.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(19133..19777)
                     /locus_tag="VWX64_001514"
     CDS             complement(19133..19777)
                     /locus_tag="VWX64_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU9190963.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(19749..>20039)
                     /locus_tag="VWX64_001515"
     CDS             complement(19749..>20039)
                     /locus_tag="VWX64_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9190964.1"
                     /translation="YYAHPYASWERGTNENHNRLIHRWLPKGTKKMTPKEVAFIEKWI
                     NNYPKKCLNYKSPREDFLMANLNLKFSVRNKSRNRFKFCRSFKYPARRCSWC"
BASE COUNT         6152 a         3642 c         4228 g         6017 t
ORIGIN      
        1 gatgacaaaa atacaaatga atagaaaata aattagtaag ctgatgaaat ttttctcaag
       61 agaagccatt tataggtgaa aatggtataa tatagtgaga aggatagagg agaagtgtaa
      121 attgatcgca caactagata caaaaacagt ctatagtttt atggaaagcg tcatttcgat
      181 cgaaaagtat gtgagagcag ctaaagaata cggctacact catttggcta tgatggatat
      241 tgacaatctt tatggcgctt tcgactttct agagattaca aaaaaatacg gcattcatcc
      301 tttgctaggg cttgaaatga cagtgtttgt agatgatcag gaagtgaatt tgcgcttttt
      361 agctctatct agtgtgggct atcagcagtt gatgaagctt tcgacagcca agatgcaggg
      421 ggagaaaact tggtcagtcc tgtcccagta cctggaggat atcgcggtca ttgtgcctta
      481 ttttgataga gttgagtcgt tagaactagg ctgtgattac tatatagggg tttatccaga
      541 aacactagca agcgaatttc atcatcctat cttacctctt tatcgggtca acgcttttga
      601 aagcagggat agagaagttc ttcaagtttt aacagcgatt aaagaaaatc taccgctcag
      661 agaagttccc ttgcgttcga gacaagatgt ctttatatca gcaagttctt tagagaaact
      721 attccaagag cgttttccgc aagctttgga caatttagaa aagcttattt caggcatttc
      781 ttacgacttg gatattagtc tgaaactgcc tcgttttaat ccagctagac cagcagtaga
      841 ggagttgaga gagcgtgctg aactggggtt tgttcagaag gggttgacta gtaaagaata
      901 tcaagataga ctagaccaag aattgtctgt tattcatgat atgggctttg atgattattt
      961 cttggttgtt tgggatttgt tgcgttttgg acgatcgaat ggctattata tgggaatggg
     1021 aaggggttct gcagtaggca gtttggtttc ttatgcctta gacatcacgg ggattgaccc
     1081 agtagagaaa aatctgattt ttgaacgctt tcttaatcgt gaacgctata ccatgcctga
     1141 tattgatatt gatatcccag atatttatcg tccagatttt atcagatatg ttggtaataa
     1201 atatggtagt aaacatgcgg cacaaatcgt tactttttca acctttggag ccaagcaagc
     1261 tcttcgagat gtcttgaaac gctttggtgt gccagagtat gaattatctg caattactaa
     1321 gaaaatcagt tttcgtgaca atcttaagtc ggcctatgag ggcaatctcc agtttcgtca
     1381 gcaaatcaat agtaagttag aataccaaaa agcttttgag attgcttgca agatagaggg
     1441 ctatccaagg caaacctctg tccatgcggc tggtgttgta attagtgacc aagatttaac
     1501 caactacatt cctctaaagt atggtgatga aattccactg actcagtatg atgctcatgg
     1561 agttgaggct agcggacttt tgaagatgga ctttctggga ctacgaaatt tgacctttgt
     1621 ccagaagatg caagagttgc ttgctgaaac agaaggtatt caccttaaaa ttgaagaaat
     1681 agatttggaa gacaaagaaa cgttagattt atttgcctct ggaaatacaa aaggtatctt
     1741 tcaatttgag caacctggtg ccattcgctt gctcaaacgt gttcaaccag tctgttttga
     1801 agatgtcgta gcaactactt ctctaaatcg accaggtgca agtgactaca tcaataattt
     1861 tgtggcaagg aagcatgggc aggaagaagt gactgttcta gattcagctc tggaggatat
     1921 tttggctcca acttatggca ttatgctcta tcaggagcag gttatgcagg ttgctcagcg
     1981 atttgctgga tttagtcttg ggaaggccga tattttgcgt cgagctatgg gtaaaaagga
     2041 tgcctctgct atgcatgaga tgagggcttc ctttattcaa ggctccatag aagcaggcca
     2101 tactgcggaa aaatcagagc aggtttttga tgttatggag aagtttgcag gttatggatt
     2161 taatagatct catgcctacg cctactcagc cttggccttc cagttggctt atttcaaaac
     2221 gcattatcca gccatttttt atcaggtcat gttaaattat tccaacagtg attacttaat
     2281 agatgcactt gaagcaggtt ttgaagtagc ctctctatcc atcaatacta ttccctatca
     2341 cgataaaatt gccaacaagt ctatctatat aggtttgaaa tcgattaagg ggctcagcaa
     2401 ggacttggcg ctttggatta ttgaacatag accttattct aacattgaag attttatagc
     2461 taaattacct gagaattatc tgaaacttcc tctgctagaa cctttggtaa aagttggtct
     2521 tttcgattca tttgaaaaaa atcgtcaaaa agtatttaat aacttagcta atctatttga
     2581 atttgtgaaa gagttgggaa gtttgtttgg agatgctatt tatagttggc aggaatcgga
     2641 agattggacg gaacaagaaa aattttatat ggaacaagag cttttaggga taggtgtcag
     2701 caaacatcca ctacaagcta ttgcaagtaa ggctatttac ccgattaccc caatcggaaa
     2761 tttgtcagaa aatagctatg ctattatttt ggttgaagtt cagaaaataa aagtgattcg
     2821 taccaaaaag ggtgaaaata tggccttctt acaggcagat gatagtaaga aaaaattgga
     2881 tgtcactctc ttttcagact tatatcgtca ggttggacag gaaataaaag agggagcctt
     2941 ctactatgta aaaggaaaaa tacaatcacg tgatggccgt ttgcaaatga ttgcacaaga
     3001 aataagagaa gcagttgctg aacgcttttg gatacaggtg aaaaatcatg aatcggatca
     3061 agaaatttca cgtattttag aacaatttaa aggcccaatc ccagtcatca tccggtatga
     3121 agaggaacag aaaaccatcg tttctcccca tcattttgta gctaaatcca atgaattaga
     3181 ggagaaattg aatgaaatcg ttatgaaaac gatttatcgc taaaaatacg gaaaatagaa
     3241 gaattttaaa atcaaatgtg atataatcaa gaagaatgtt aaaagaaaaa ggagcataaa
     3301 ccaatatgaa acgtattgct gttttgacta gtggcggaga cgcacctggt atgaacgctg
     3361 ctatccgtgc agttgttcgt caagcaattt cagaaggaat ggaagtgttt ggtatctatg
     3421 acggatatgc tggtatggtt gccggtgaaa ttcatcccct agatgcagct tcagtaggag
     3481 acatcatttc tcgtggtggt acttttcttc actcagctcg ttacccagag ttcgctcaac
     3541 ttgaagggca acttaaaggg attgagcaat tgaaaaaaca cggaattgaa ggtgtagttg
     3601 ttatcggtgg tgacggatct taccacggcg ctatgcgttt gactgaacat ggcttcccag
     3661 ctattggtct tccaggtaca atcgataacg atatcgttgg tactgacttt acaatcggtt
     3721 ttgacacagc ggttactact gccatggacg ctatcgataa gattcgtgat acatcatcaa
     3781 gtcaccgtcg tacttttgta atcgaagtta tgggacgtaa cgctggtgat atcgctcttt
     3841 gggctggtat tgcaactggt gctgatgaaa tcatcatccc tgaagcaggc ttcaagatgg
     3901 aagatatcgt agcaagcatc aaagctggtt atgaatgtgg taaaaaacac aatatcatcg
     3961 tcttagctga aggtgtgatg tcagcggctg aatttggtca aaaacttaaa gaagctggag
     4021 atacaagcga ccttcgtgta acagaacttg gacatattca acgtggtggt tctccaactg
     4081 cgcgtgaccg tgttttggcg tcacgtatgg gtgcacatgc tgttaaactt cttaaagaag
     4141 gtatcggtgg tgttgcggtt ggtattcgta acgaaaaaat ggttgaaaat ccaattcttg
     4201 gtactgcaga agaaggggca ttgtttagcc ttactgcaga aggtaagatt gtggttaaca
     4261 acccacgcaa agccgatatt gagctatcta gcttgaataa gagcttgtca taatttacaa
     4321 tttagttaat aagaccaaaa aggtcatata tataaaggag tcacaaaaat catgaacaaa
     4381 cgtgtaaaaa tcgttgcaac tttgggtcct gcggtagaaa tccgtggtgg taaaaaattc
     4441 ggtgaggacg gatactgggg tgaaaaactt gatgttgaag cttcagctaa aaacattgct
     4501 aaattgattg aagctggtgc taacacattc cgattcaact tctcacacgg cgaccaccaa
     4561 gaacaaggtg agcgtatggc aactgttaaa cttgcggaaa aaattgcagg taaaaaagtt
     4621 ggtttccttc ttgatacaaa aggacctgaa atccgtacag aattgttcga aggtgaagct
     4681 aaagaatatt catacaaaac tggtgaaaaa attcgtgttg caactaaaca aggaatcaaa
     4741 tcaactcgtg aagtgattgc gttgaacgtt gctggtgctc ttgatatcta tgatgatgtt
     4801 gaagttggtc gtcaagtttt ggttgacgat ggtaaacttg gtcttcgtgt ggttgctaaa
     4861 gatgatgcaa ctcgtgaatt tgaagttgaa gttgaaaacg atggtatcat cgctaaacaa
     4921 aaaggtgtga acatccctaa cactaaaatt cctttcccag ctcttgctga acgcgataac
     4981 gacgatatcc gtttcggtct tgaacaaggt atcaacttca tcgcaatttc attcgtacgt
     5041 actgcaaaag atgtgaacga agttcgtgca atctgtgaag aaactggaaa cggacatgtt
     5101 caattgttcg ctaaaatcga aaaccaacaa ggtatcgata acttagatga aatcatcgaa
     5161 gcagctgatg gtattatgat tgctcgtggt gatatgggta tcgaagtacc gttcgaaatg
     5221 gttccagttt atcaaaaaat gattatcaag aaagtcaatg ctgcaggtaa agttgttatc
     5281 actgcaacaa acatgcttga aacaatgact gaaaaaccac gtgcaactcg ttcagaagta
     5341 tcagacgtat tcaacgctgt tatcgacgga actgacgcta caatgttgtc aggcgagtct
     5401 gcaaacggta aatacccact cgagtcagta actacaatgg ctacaatcga caagaacgct
     5461 caagctcttc ttaatgaata cggacgtctt gattcagatt catttgagcg taactctaag
     5521 acagaagtaa tggcttctgc tgttaaagat gctactagct caatggatat caaattggtt
     5581 gtaactctta ctaagacagg tcatactgca cgtttgattt ctaaataccg tccaaatgct
     5641 gacatcttag cattgacatt tgacgaattg acagaacgtg gcttgatgtt gaactggggt
     5701 gttatcccaa tgttgacaga tgctccatct tcaactgacg atatgttcga aatcgctgaa
     5761 cgtaaagcgg tagaagcagg tctcgttgag tcaggcgatg atatcgttat cgttgctggt
     5821 gtgccagtag gagaagctgt tcgcacaaac acaatgcgta tccgcacagt acgttaagaa
     5881 aaatataaaa acctatcata tccagcttta gagcttgtgt gataggcttt ttgtatagag
     5941 ggtaagaaat aggcaaaact ttcataatgg attgatactc ttcgaaaatc tcttcaaacc
     6001 acgtcagcgt cgccttaccg tactcaagta cagcttgcgg ctagcttcct agtttgctct
     6061 ttgattttca ttgagtatga aataagatat gcataaattg attagaaagt caaatgaatt
     6121 tctacaaatg ttttagcaat cgcaatctac ttgtctagat tcgatctgat atattttcga
     6181 tttaatgata tggtatttaa aacctccaaa gtagcttgct ccattctttt acctacgtga
     6241 gtctagatgt tatttactgt tttagcgttt ttgtgttcta ctctaaccat tatagcattc
     6301 ttctcagcta gtgtactaag gagtgtgtgc ctgaaaatat gggaactaag gggctggttt
     6361 atcggtttct ctagtttagt atttgccttt tgcaaagtga tcttaaatgc ctttctctaa
     6421 atttacatat cactattgtt taacaaaatc taatctattt taggtcactt attctttttt
     6481 tgaaatgtag aataaacttt ttcaaagttt ttcgaatctt ttaaaatctg tttgttttat
     6541 atcgccattc tccccctttt ttaattctcc ctatatagcc tgacaacttt cccgatggta
     6601 cgaatatggt tgctttcgtc taggtggatg tcggagtatt cgggattgag tttttttgag
     6661 gtagccttgg cggagtttct tgacatagtt agtgccgtct acttggaaga tgccgatggt
     6721 attatagtca atctgtgggg tattcttgat aaataggtag tcgctgtttc ttatctttgg
     6781 ctccatggac ttgctgacga cataagcgat tgggtcgtag tcgtctggga taatggaaac
     6841 tccatatcta aatcgttgtc ctgcatcgag cggctacctg cagagataaa ctacctaaca
     6901 cgagagtaag tagtctgtct gtagtcgtcc agtctgatga tttttacgat acttcgtttt
     6961 tctgatcata cagttgcctc tcggcatagg tcagaacttt accttgtctg ggtggttccc
     7021 gttggtcgta gatagattgg atatcgctag gagaatcctt ttgaactgga ggaaagaggg
     7081 catcgatcaa gctactgaat actttaacta agtcaaatat agtatttttc ttagtagacc
     7141 taaccctttt ttcataattt ctaatggtgt ttttacttat acctatctta gtacccaatt
     7201 cttattgagt ccaaccatta ctagtctata ttgttttata gttgattgag tttggaatag
     7261 tacgctgtag ctgctaaaac atttctagaa attaatttga ctttcctaat agagttgttc
     7321 atatcttatt tcaatctatt atgtttttca cctctaacaa tcgcaatctc ttctttatcc
     7381 atgaatgaaa tcgctttcta tttttgtaag taaagcataa cacgaaatcc acgaaaatga
     7441 aaacctttgt tgtgttttcg taaaaaattt gttgacagag cacgaaacgc ctactataat
     7501 taaatcaagc ttaaggaaat aacaaaaaaa caaatcggag ggaaagacga tgaacacatt
     7561 aaatgagaaa gtaatcaata tctgtaaagc aatagttaaa gaaactttaa tccaagacat
     7621 ttaggagaaa gaaatgaaga aatcaagaaa attagccaca ttaggaatct gttcagcctt
     7681 gtttttaggc ttggctgctt gtcaacaaca acatgctact tctgagggga cgaatcaaag
     7741 gcaaagcagt tcagcgaaag ttccatggaa agcttcatac accaacctaa acaaccaggt
     7801 aagtacagaa gaggtcaaat ctctcttatc agctcacttg gatccaaata gtgttgatgc
     7861 attttttaat ctcgttaatg actataatac cattgtcggc tcaactggct tatcaggaga
     7921 tttcacttcc tttactcaca ccgaatacga tgttgagaaa atcagtcatc tctggaatca
     7981 aaagaagggc gatttcgttg ggaccaactg ccgtatcaat agttattgtc ttttgaaaaa
     8041 ttcagtcacc attccaaagc ttgaaaagaa tgaccaattg cttttcctag ataatgatgc
     8101 gattgataaa ggaaaggtct ttgattcaca agataaggaa gagtttgata ttctattttc
     8161 gagagttcca actgaggcaa ctacagatgt caaggttcac gctgaaaaga tggaaacatt
     8221 cttctcacaa tttcaattca atgaaaaagc tcgaatgctg tctgtagtct tgcacgacaa
     8281 tttggatggc gagtatctgt ttgtaggcca cgttggggtc ttagtacctg ctgatgacgg
     8341 tttcttattt gtagagaaat tgactttcga agagccctac caagcgatta aatttgctag
     8401 taaggaagat tgctacaagt atttgggcac caagtatgcg gattatacag gcgagggact
     8461 ggctaagcct tttatcatgg ataatgataa gtgggttaaa ctttaatagt gttatgatat
     8521 gacagtaatc ttaggatttt tatttctatt tttgatgagt tggtgggtta tttcaatcgt
     8581 taatagccag aaaccacgca aaaatgaaac atttattggc tatatccaaa gatacgatat
     8641 tgatgggaat ggctatcaat cattaccgtg tcctcagaac tgagaggagt tcttgaaacc
     8701 gtaaaaccgc tttgaacaag agttacttca acccattggc tccgacggag taagttgctt
     8761 tcgtgaatac caaaatcagc cgcaatttgt tcataagttc gatattctcg cacatattga
     8821 agagtggcca taagaaggtc ttctaggctt aatttaggtt ttcgtccacc ttttgcgtgt
     8881 ttaagttgat aagctgtttt taatacagct aacatctctt caaaagtggt acgctgaaca
     8941 ccaacaagac atttaaatcg tgcatcagtt agttgtttac ttgcttcata attcatagaa
     9001 ctactatacc atattttgtt tcgcaggaag tctaatgcta aaatcttatc agtgagaaga
     9061 tttcttaaag tttattcttt gtagtttcat ctgtattagt acataattta acttagagaa
     9121 aataggagga ctaatcgaat ggaattaaaa gattttacag aaaaagaaca ggaaatgatt
     9181 aagaaaaggc ttacaatgtc taatgttagt gacaaagaaa ctgctgagaa gattctggcg
     9241 ctagtaccac aagacttgat taagcgaatc ccgttttttg tcagaaaaca tgctacaaca
     9301 cgtacgatta aacgcatttc aattgaacac cctgaactct acgctgtagc tcaaacaagt
     9361 ggtgagattc cagaaaaaga acgcgaagaa ttgcgtcaga ttatcacaac tatctttgaa
     9421 caaaagatga ataagcatag tattaagtag agaatgaaaa aatattttat tggctgtttg
     9481 ggaagcaatg cctatcatag caaggatttt cttcaagaac tagattcgca ggtctatttt
     9541 ctaaatccat atgaaaagca tcttcgagat gaaacagaat tgaaatcatg gtttaaaaat
     9601 gagattgtag aggaagaatc tatttgtctg ataggtcatt ctcttggagg agatttagct
     9661 cgttatctcg catcggaatt tgaagaagta aagaaactga ttcttttgga tggtggctat
     9721 ctagatttag ataagatttt acctttggat acagagttag aggaaactaa aaattatatc
     9781 aaatctcaaa ttatttcgga cttagatgtt cttacttcta aagaaaaatc tgaagcaaag
     9841 cattggtcag aaaatatgga gaaagctgta agacagtctt atcactggaa tgttgagtat
     9901 aatagatatg agttggctat aaattatgaa aatatagaag cgatactccg cctacggaga
     9961 aaaatacaag cttttaagag agaagtggga gataccttgt ttattagtcc tcgctatcct
    10021 aatgaagcta catggagaga ggaagcccta aaagaattgc cagactattt tgatactatt
    10081 tttttagaaa actttggcca tgagctttat actcaagcac ctaaagaaat cgctagtcta
    10141 atgaatgagt ggctcgctta ttttctatga gctacttgta ttgctggaaa tggtataaga
    10201 tgaaaatcta caagtcacta attttcatat aacaaaaaaa cgaacaggct ctttttctgt
    10261 tattcagaag agaacttgtt cgtttttatc ttgattttct taaaaagctc tatatacata
    10321 gggattttct ggtttatcga ctttggtaaa gctgtcgatt tccaaggttg gaaggttttg
    10381 tttgagttct ttatggtagt gattgaccag ttttcctttg gctgtaatcc aggtgttgtt
    10441 ttcatactgc cgggtattgc ccttggtcag caatccatag acaccagaat ctgcgataca
    10501 gtggataatg ccgaatcgga acagaaattg actattggca tgactggggt cgttatagac
    10561 aaagcctgta aactggattg tcttgccctc aaattcatct ggatagtcgt agatagcctc
    10621 catgacttcc atatagtttt cattagtgat ctgaatacta tcttgggata agtatttatc
    10681 cgccgccgtt cgcatttcct tttcataggc tgattttgaa aaataagaac tagtatctgg
    10741 tttcaaatat tggcttgtag tcccttcact tgtctgaata gctagatccg ttccttccga
    10801 tagggggaaa tgataacctt tagcagaaac ggtctgagaa tccaagctaa cagttgggaa
    10861 agttaagccg atgacaagtg gaatagccag aagagaaata ctcgtcatct tggccaatcg
    10921 gctgttcaga tgactgtggg ttttgacttg cttcatccag atatacaatt gaacaattgc
    10981 caagataaag gaaagcacca tggagatata ggccagatag gaatagtgca tgttgatgta
    11041 ctggtttagt ttgcccgaca gatggaggta aatagtcagt tcaaaatagc cagctaaaac
    11101 taaaaatcga atcataggat gactccaatc aagagagaat agactaagac gacaagagtt
    11161 acaattgtta tgaagtgact gataaatcgt gctttcaagt aatttttcat catgagaata
    11221 tttttgatat ccagcattgg accaatgacg agaaaggcca gaactggtgc caaaccgaaa
    11281 ctcgagagaa gagaagcacc tataaaggca tccgcctcac tacagagcga aagaagaaag
    11341 gctaaaatca tcaagagcag gatggcaaaa agaggggtcg cactgataga ggtcagaatc
    11401 cgagtcggaa cgtagacctg tattatagaa gcaaagaggc agccaaatac caaataacgc
    11461 cccgtatcaa aaaattcatc aatggcctgc acaaagactt gaaaaacttt ttttgcagaa
    11521 ctcaagtaag aaaaatcatg ctcatgacaa gccagacgat tttctttctg aatcggttct
    11581 tgccagaaaa atcctagaaa aattcctagt attacagcca caagaatgga acccagagct
    11641 cgtaataggg cgacatggaa ggagttgcca aaggcagaat aggtcgcaaa aagaacaatg
    11701 ggattgataa caggtgctgt cacaagaaaa ggaacggccg tgtaacttgg aacctttttt
    11761 tccagaaaac gattgatgat ggggacgatt ccacattcac aagaagggaa aaacataccg
    11821 acgaaggtcc caaaaaagat tctcccccaa cgatttcgag ggagaaaatg ataaaccttg
    11881 tcaggtgtga tataaacttc aatcagccct gagataatgc ttcctatcag aacgaaggga
    11941 agggcttcaa tgataatgga gagaaaaatg gctccagttt gaagtacact agatgggagt
    12001 tgttgaaaag cagtcatcta gtttttcttt tctgctttga cttttttctc tttgtcatca
    12061 gggaaagtaa cttgtttcaa atcagggagt ttagcaaact cttcaaacat cttgtccaag
    12121 tcgtctcgtt ttgtaaattt tacagccata ggtgtacctc gattctaaat tctacctcta
    12181 ttatactatt attttgcgga aaagggagtt ttttaatttg ttttcgatag ttgatactct
    12241 tcgaaaatct cttcaaacca cgtcagcttc gccttaccgt agtacggtta ctgacttcgt
    12301 cagttctatc cacaacctca aaacagtgtt ttgagctgac ttcgtcagtc ttatccacaa
    12361 cctcaaaaca gtattttgag cagcctacgg ctagcttcct agtttgcttt ttgattttta
    12421 ttgagtatga aaaggattgg agaaagcctt ccagcttgtg gtataataga tttatggata
    12481 aaaaatatga aaaaatctct caggatttgg gagtgacgtt aaagcaaatt gataccgttc
    12541 taagtttgac agctgaaggg gcgactattc cctttatcgc gcgttatcgc aaggacatga
    12601 ctggtagtct ggatgaggtg gcgattaagg ctattattga tttggataaa agtctgacaa
    12661 atctcaatga ccgtaaggaa gctgtcttag ctaagattca agaacaaggt aagttgacca
    12721 aggaattgga agaagctatc ttagttgccg aaaaattagc agacgttgaa gaactctatc
    12781 ttccttataa ggaaaagcgt cgtaccaagg caaccattgc ccgtgaagct ggactctttc
    12841 ctcttgctcg cttgattttg cagaatatag ttgacttaga gaaagaagct gaaaagttcg
    12901 tctgtgaagg atttgcgact ggcaaggaag ccttgaccgg tgcagttgat attttggtcg
    12961 aagccttatc ggaagatgtg accttgcgtt ctatgactta tcaggaagtg ctgagacact
    13021 ctaaacttac ttctcaagcc aaggatgaaa gtcttgatga aaagcaggtt tttcagattt
    13081 attatgattt ttcagagaca gttggaacta tgcaaggcta tcgtaccttg gctctcaatc
    13141 gtggggagaa acttggtgtc ttgaagatcg gttttgaaca tgcgacggac cgtattcttg
    13201 ccttctttgc tactcgtttc aaggtgaaaa atgcttatat tgatgaagtt gttcagcaat
    13261 ccgttaagaa aaaggtcttg cctgctatcg agcgtcgtat tcggacagaa ttaactgaga
    13321 aagctgaaga aggagctatc caactttttt ctgacaatct gcgcaatctc ctcttggttg
    13381 ctccactgaa agggcgcgtg gttcttggat ttgacccagc ctttcgtaca ggtgccaagt
    13441 tagctgtcgt ggatgcaaca ggaaaaatgc tgacaactca ggttatttat cctgttaaac
    13501 cagcatcagc tcgtcaaatc gaagaagcca agaaagattt agcagattta attggtcaat
    13561 acggtgtaga gattattgcc attggaaatg gaacggccag tcgtgaaagt gaagcttttg
    13621 tagcggaagt tctgaaagat ttccctgaag tcagctatgt tatcgttaat gaaagtggtg
    13681 cttctgtcta ttctgccagc gaacttgctc gtcaggagtt tccagacttg accgttgaaa
    13741 aacgctctgc catttctatc gcccgtcgtt tgcaagatcc tcttgcggaa ttggtcaaaa
    13801 tcgatcctaa gtcaattggt gtcggtcaat accaacacga tgtcagtcag aagaaactat
    13861 ctgagagtct ggactttgtt gtcgatacag tggttaacca agttggtgtc aatgtcaata
    13921 cagctagccc agctcttctt tcacacgtag ctggactcaa caaaactatc tctgaaaata
    13981 ttgtcaaata ccgcgaggaa gaaggaaaaa tcacttcacg cgcccaaatc aagaaagttc
    14041 ctcgtctggg agccaaggcc tttgagcagg ctgctggttt ccttcgtatc cctgaaagta
    14101 gcaatatcct tgataataca ggagttcacc cagagaatta cactgcagtt aaggaactct
    14161 tcaaacgttt agatattaaa gacctaaacg aagaagccca aagcaaactc aagtcccttt
    14221 cagtcaagga aatggctcaa gagctagacc tcggtccaga aacccttaaa gatatcattg
    14281 cagatcttct caaaccaggt cgagatttcc gtgattcctt tgacgcacct gtgcttcgcc
    14341 aagatgtcct agatatcaaa gacctagtgg taggtcagaa gctagaaggt gttgtgcgta
    14401 acgttgttga cttcggtgcc ttcgttgata tcgggattca cgaggacggc ttgattcata
    14461 tttctcatat gagtcgcaag tttatcaaac accctagtca agtggtgtca gttggagatt
    14521 tggtgaccgt ttgggtcaag aaaattgata ctgaacgtga aaaagttaat ctgtcgctcc
    14581 tcgctccaaa tgaaactgac tgattatgtc aagcaggttt cactagaaga cttcgggaga
    14641 gcttttatcc atcatgtcca gtggaatagg cgtctacgtt cgacaggtgg gcgatttttc
    14701 cccaaagatg ggcatctgga ttttaatccc aaggtttatc agaaactggg tatggaggtt
    14761 tttaggaaaa ttgtccgaca tgaactctgt cattatcacc tttatttcca agggaagggc
    14821 tatcaacaca aggatcggga ttttaaggaa ctgttgaaag cagtggatgg attaaggttt
    14881 gtaccatcct tgcccaatag taactctaaa ccactcaagc tttatcgttg tcaatcctgc
    14941 cagcaaaggt atcagcgcaa gcgtaggatt gataccaaac gctatcgctg tggactttgt
    15001 cgaggtaaat tgcttctgat aaatcagcct gaggactgat gaaagccgag cctccccgtg
    15061 atatactatg tctaacctag cagaaagagg aaatatcatg aacagtaaat tttataaaat
    15121 gagacgcaat cgcatgattt caggagttct ggcaggtctg tcagacaagt ggaattttga
    15181 tgttacccta gttcgtttct tgtttgccat ttttacagtt gcaaactttg gacttggcgt
    15241 gattatctat atcatcctag cttctatcat gcctaccaag gaagaaatcg aagcagaaat
    15301 gtacggaaca ggcccacgta aacgcaaaga agcccaagcc attgacgaca atgaaggctg
    15361 gttttggtga ggttctacag aagatttgga ataagcaaaa agctttaaat caatagtcta
    15421 aactgcttga tttaaagctt ttttactttt atactcaata aaaatcaaag tgcaaactag
    15481 gaagccagcc acaggctgta atttagtcgg caatgtgaag ttgacatagt ttgcactttg
    15541 atttttgaat agtattaata atatttcgcc agcttcatcc acaaactata gtggattgga
    15601 actagaatag gacacctata cttctaaaaa attgttagaa attgatttga ctgtcctgat
    15661 cgatttgtcc tgttcttatt tcattttact ataaaagcag taatttaaac gcagtttttt
    15721 aatctatttt tgctgttgag acaatacatt tttggaaaaa tggtggatgc tgataacaac
    15781 tgataaccag caaataacat aagcagtgcc ggtaaattct gtaccgataa agtgtgtgtg
    15841 ttcaactaag agctgaccga tgaatggaga gagcagatag agaagtccga tgagtatatg
    15901 ttctttgtgt ttcattaaag cgcaccttct ttccttatag gttgaacgac ttgcaagtgt
    15961 taaattgaat ggtatgttat ctaggtaacc ttactaaaat gttagttccc gcttcctcct
    16021 tttcaaagta agccttttca cacttatatt ttacaacttt aaaaatagga aatcaaatca
    16081 ttttctaagt aattttgctt atatttcacc caatcttaca aaaatgtaag attaaagtct
    16141 cttttgtaag gttaggttat ggcaagcggt ctttttttga tgtaaactag actcataaag
    16201 aacaaaggag taacatcatg aaacaaatct tacataagaa aactagaaaa ccaagtcaca
    16261 aagaaattga gcgcgttcag ctgggatgca ctatgatgca agctacattt catttgatgg
    16321 gatattaaga aaggagattc tcatgacact tttagatgta aaacacgttc aaaaaattta
    16381 taaaacacgt tttcagggca accaagtaga agccctcaag gatattcact ttaccgtcga
    16441 aaagggtgac tacgttgcca tcatgggtga gtctggttct ggtaaatcaa ctcttctcaa
    16501 tattctagct atgctggata aaccaagtcg tggtcaggtt tacttgaatg gaactgacac
    16561 cgcaaccatt aaaaattcac aggcctctag cttccgtcgt gaaaagttgg gctttgtctt
    16621 ccaagacttt aacttgctag atactctatc tgtaaaggac aatatcttgc ttccgcttgt
    16681 cttgtcaaga agacctatta cagagatgat gaagaaattg gtggtgacag ctgagaatct
    16741 gggaataaac caattacaag agaagtaccc ttacgagatt tctggtggtc agaaacagcg
    16801 tgtagcagta gcccgcgcca tcatcacaga acctgaaatt ctccttgcgg acgaaccgac
    16861 aggagctctt gactccaagt catctgcagc cttacttgat gtctttgatg aaatcaatga
    16921 gcgcggccaa accattctca tggtaaccca ctcaacagca gcagctagca gagctaaacg
    16981 tgtactcttt atcaaagacg gcattcttta caatcaaatc taccgtggag agaagacaga
    17041 acgtcagatg ttccaagaaa tctctgatac cttgactgtc atggcaagcg aggtgaatta
    17101 gtatgtttcg attaaccaat aagttagcgg tatcgaactt gattaaaaac cgcaaactct
    17161 actatccttt tgcgctggct gttctcttgg cagtcactgt cacctatctc ttttactctc
    17221 taaccttcaa tcctaagatt gcggaaatcc gtggaggaac aaccattcag gctacacttg
    17281 gatttggtat gtttgtcgtc acccttgcgt cagccattat cgttctctat gccaatagtt
    17341 ttgtcatgaa gaaccgttcc aaggaactag gaatttatgg catgttgggc ttggagaagc
    17401 gtcatcttat cagtatgacc tttaaggagt tagtggtatt tgggattcta actgttggag
    17461 cgggtatcgg tattggagcc ttgtttgaca agttaatttt cgctttcctg ctcaaactaa
    17521 tgaaattgaa ggttgagctg gttgctacct tccagacgaa agttgtcatt acagtgcttg
    17581 ttgtcttcgg tttgattttc ctaggcctca tgttcctgaa tgcccttcga atcgcccgta
    17641 tgaatgccct ccagctctct cgtgagaaag ctagtggaga gaaaaaaggt cgcttccttc
    17701 ctctccaaac cattcttggt tccataagtt taggaattgg ctattatctt gcccttacgg
    17761 taaaagatcc tcttacagcc ttaacaacct tcttcatagc tgttttactg gttatctttg
    17821 ggacttatct cttgtttaat gcagggatta ccgttttcct ccaaatctta aagaaaaata
    17881 agaaatacta ttaccaacca aataacctca tatctgtttc taacttgatt ttccgtatga
    17941 agaaaaatgc agttggacta gccaccatcg ctatcttgtc aacaatggtt ttggtaacca
    18001 tgtcagcagc gacaagcatt ttcaattcct cagaaagctt taaaaaagtt ctaaatcctc
    18061 atgattttgg ggtttcaggg caaaatgttg aaaaagaaga cttggacaaa ctcttgagcc
    18121 agtttgcaag tgacaaaggt tataagatta aagaaaaaga agtatttcgt tacacttact
    18181 ttgctgttgc gaatcaagaa ggaaccaagt taactatttt tgaaaaagga caaaaccgtg
    18241 tccaaccaaa aacagttttc atggtatttg accaaaaaga ttatgaaaat atgactggtc
    18301 aaaaactgtc tctatcagga aatgaggtcg gactctttgc aaagaatgag ggagttaaag
    18361 aacagaaagc tctaactcta aatgatcatc aattttctgt aaaagaagaa tttactaaag
    18421 attttattgt caaccatgtt ccaaatcagt ttaatatttt gactgctgat tacaattacc
    18481 ttgttgtacc tgatttacaa gcctttttgg atcaattccc agattcggct atctataatc
    18541 agttttacgg tggtatgaat gtaaatgcca gtgaagcaga acaactcaag gtcgctgagg
    18601 agtatgaaaa atacttacaa aagtttaatg ctcaattaaa cactgaaggt aactatgtgt
    18661 atggtagcac tctagcagat gctagttctc agatgagtgc cctctttggt ggtgtcttct
    18721 ttatcggtat tttcctatcc attatcttta tggtcggaac tgttctggtc atctactaca
    18781 aacaaatttc tgaaggctac gaagaccgtg aacgctttat tatcttgcag aaagtcggtt
    18841 tggaccaaaa gcaaatcaag caaaccatca acaaacaggt tttaactgtt ttcttccttc
    18901 ctttgctctt tgccttcata catctcgcct ttgcctacca tatgcttagc ctgattttaa
    18961 aagtgattgg tgtactggat acgactatga tgttgattgt gaccttgtct atctgcgcta
    19021 tcttcctcat cgcctatgtg ctgattttca tgattacttc aagaagttat cgcaagattg
    19081 tgcaaatgta aaaaagatac ctcgacttca aaatcgaggt atttcttgta ttctaaatgc
    19141 tgaaaagttg ttcgagcagg aaggtaactc ccatggtcaa gagaccaata gcaaggttcc
    19201 gaatcatagc tgttctagtc ggatcctttc caagtctggc actagtgtaa ccagtgagaa
    19261 gaagggccac accgacaata aggacagtag cagggatgcg atattcactt gggaatatgg
    19321 tcactgacag cattggaggc aaacttctaa ggaaaaaggc aacgaagcta gaaatggcag
    19381 cgtgccaagg attggtaaat tcttcatact caatcccata tttttcctct accagagcct
    19441 tgagtggatt tttaagaaag atcttattgg tcaagagttg ggcagaagtt ttgcattctc
    19501 cattttggat ataagcagca tagagggatt ttttggctag ttccctatct tggtctaaca
    19561 agagtttttc tcgcgaaacg gcagcttcct cggtatcttt tggagttgaa acggatacat
    19621 attctccacc agccattgaa aaggcaccag ctaagatagc cgcaaatcct gataaaaaga
    19681 taatccagat attggtcgtg gcactggcaa ccccgataac cacaccagca atggaaataa
    19741 ttccatcgtt agcaccaaga acacctgcgc gcaggatatt taaacgacct gcaaaatttg
    19801 aatcgatttc gtgatttgtt tctgacgcta aatttcaagt tcaagttagc catcaagaag
    19861 tcttctctgg gtgacttgta gttcaagcat tttttaggat agttgttaat ccacttttcg
    19921 atgaatgcga cttctttggg agtcattttc ttggttccct taggtaacca tctatgaatg
    19981 agcctgttgt gattctcatt agttcccctt tcccaagagg cataggggtg cgcataata
//
LOCUS       DAVKBC010000035        18492 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVKBC010000035 DAVKBC010000000
VERSION     DAVKBC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.035"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..180
                     /locus_tag="VWX64_001516"
     CDS             <1..180
                     /locus_tag="VWX64_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190965.1"
                     /translation="FNHSIKNIEYIKARNIKTSSDSDIELESDVDGDKSDNLPVDIKI
                     LGQHIEVYSVPKKQS"
     gene            380..3655
                     /gene="rexB"
                     /locus_tag="VWX64_001517"
     CDS             380..3655
                     /gene="rexB"
                     /locus_tag="VWX64_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU9190966.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADSKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3652..7302
                     /gene="addA"
                     /locus_tag="VWX64_001518"
     CDS             3652..7302
                     /gene="addA"
                     /locus_tag="VWX64_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU9190967.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVELKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNSQKWL
                     SDSFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQSVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGRLILLKENFRSSSEVLSTTNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALKMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYKNKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEAQVVKV"
     gene            7472..8650
                     /locus_tag="VWX64_001519"
     CDS             7472..8650
                     /locus_tag="VWX64_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190968.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8859..14720
                     /locus_tag="VWX64_001520"
     CDS             8859..14720
                     /locus_tag="VWX64_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9190969.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTKLINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSEAVVTDKG
                     EPAVQPELPEAVVSDKGVPEVQPALSEAVVTDKGETEVQPESSDTVVSDKGEPKQVAP
                     LPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQGAEN
                     PVQPAEESTTNSEKVSPDTSSENTGEVSNKPSDSKPPVEESNQPENSGNTTSENGQTE
                     PEPSNGNSTENVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLELRNVSDLELYS
                     LSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKV
                     EKLQQEIESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNLSGTYHLGASLNANE
                     VELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFESLRGATIEKLSLKNVSISG
                     KDDIGSLANEAQNNTKIKQVHVDGVLAGERGIGGLLAKADQSSITESSFKGRIVNTYE
                     TTASYNIGGLVGHLTGSKASLTKSKATVVISSNTNSSDQTVGGIAGLVDKDAHIQNSY
                     SEGDINNSQRFGKVAGIAGNLWDRESNSENHAGRLTNVLSDVNVTNGNAISGYHYNGM
                     KITDAFSNKANKVFNVTLEKDEVVSKESFEERGTMLDASQIASKKAEINLLTPPIVKP
                     LSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVKENSILYQKEL
                     LSAVMMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFAKLAEYSLGDTGL
                     LYTPNQFLYDQDSIINQVLPELQQVAYDSEAIRKTLGISPEVKQTELYMEDQFTKTKQ
                     DLANSLKKLLSADAGLAGDNPVTRGYLVDKIKNNKEALLLGLTYLERWYNFSYGQVNV
                     KNLVMYHLDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLASHHGTTDLFST
                     LENYRKVFLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSD
                     SWKYRNMVLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLNSFVEKSAHET
                     AERQRDHYDYWYRILDEKGREKLYRNILLYDAYKFGTDHTEGKATEVANFDNPNPAMK
                     HFFGPVGNKVGHNGHGAYATEDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYG
                     RRSGLGPEFFAKGLLQAPDQPSDATITINSILKHKTSDSTEGQRLQVLDPTTRFNDAA
                     DLQNYVHNMFDVVYMLEYLEGQSIVKQLDAYQKMTALRKIENKYVKDPADGNDVYATN
                     VVKNLTEDEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAPIFSALSSEKG
                     TPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELV
                     LKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKRWPSYGTKTINNVDELQK
                     LMDEAVLQDATGTRWSNYNPEIDSAVHKLKRAIFKAYLAQTNDFRSSIFENKK"
     gene            14772..14948
                     /locus_tag="VWX64_001521"
     CDS             14772..14948
                     /locus_tag="VWX64_001521"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9190970.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            15167..16018
                     /gene="ylqF"
                     /locus_tag="VWX64_001522"
     CDS             15167..16018
                     /gene="ylqF"
                     /locus_tag="VWX64_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU9190971.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            16005..16784
                     /locus_tag="VWX64_001523"
     CDS             16005..16784
                     /locus_tag="VWX64_001523"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU9190972.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            16800..18350
                     /locus_tag="VWX64_001524"
     CDS             16800..18350
                     /locus_tag="VWX64_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU9190973.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHMIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAALNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         6026 a         3589 c         3846 g         5031 t
ORIGIN      
        1 ttcaatcatt ctatcaagaa tattgaatat ataaaggcac gtaatattaa aacttcttct
       61 gattctgata tcgaattaga gtccgatgtt gatggcgata aatcagacaa tctacccgtc
      121 gacattaaga tactgggaca acacattgaa gtgtattccg tacctaagaa acaatcataa
      181 aactcaaagc cttgttaccg aggctttttt attatgtgat tttcagtagc cagacttatt
      241 ctatctaata caagtaaagc taagtattta agatttagca gatgatgaag aaaagaaagg
      301 atggcctaaa tattttaaca gatttacgag gctaatcatg gtataatata gggtgatgaa
      361 aaattccaac gaggctgaga tgaaattact ttatactgat attcgaactt ctttgacaga
      421 aattctaaca agagaggcag aagagctagt tgcagctggc aagcgggtct tctacattgc
      481 ccccaactct ctttcttttg aaaaggaacg cgccgtgctg gaatgcttgt cccagcaggc
      541 ttctttttcg attaccgtca cgcgctttgc tcaaatggct cgttatctgg tcttgaatga
      601 tttaccagtt aaaactactc ttgatgatat cggtcttggg ttggcctttt acaaatgcct
      661 tgccgaactc gatcccaagg acttgcgtgt ttatggcgct attaagcagg atcctcaatt
      721 gatccagcag ttaattgagc tttaccatga gatgaccaaa tctcagatga gttttttgga
      781 cttggagaat ttaacagatg aggataagag gacggattta ctcttgattt ttgagaaagt
      841 aacagcctat cttaatcaag gtcagttagc ccagggaagt cagttgtccc atttgattga
      901 ggctattgag aatgacaagg taagtagtga ttttaatcaa atcaccttgg tcattgacgg
      961 ctttactcgt ttttctgctg aggaagagcg ggttgtggac ttacttcacg gcaaaggtgt
     1021 tgagattgtt atcggggctt atgctagtaa gaaagcctat accagtcctt ttagcgaggg
     1081 caatctctac caagccagcg taaaatttct ccatcatctg gcttctaaat accaaacgcc
     1141 tgctcaggac tgttctcaaa ctcatgagaa gatggatagt tttgacaagg cctctcgttt
     1201 gttggagtct tcttatgact tttcagaact cgctttggat gtcgatgaga aagaccgtga
     1261 aaatttacaa atctggtctt gtttgacgca aaaggaggag ttggagctag tagcccgtag
     1321 cattcgtcag aaattacatg agaactcaga cctgagctac aagcattttc gtattctctt
     1381 gggggatgta gcttcttacc agttatctct caaaaccatt tttgaccagt atcagattcc
     1441 tttttatctt ggtagaagcg aagccatggc tcatcatccc ttgactcagt ttgtcgagtc
     1501 tattttagct ttaaaacgtt accgttttcg tcaggaggat ttgattaatc ttcttagaac
     1561 tgatttgtat actgacctca gtcagtctga tattgatgct tttgagcaat atatccgcta
     1621 tcttggtatc aatggcttgc cagcctttca gcaaaccttc accaaatccc accatggaaa
     1681 atttaatctt gagcgtttga atgtcctccg cctgagaatt ttagcacctc ttgaaaccct
     1741 ctttgccagc cgaaaacaaa aggctgaaaa actcctacaa aaatggagtg tctttctaaa
     1801 agaaggagct gtgaccaagc agttacaaga tttgacaacc actttggaag ctgtagaaca
     1861 ggaaagacaa gccgaagttt ggaaggcttt ctgccatgtt ttagaacaat ttgcgactgt
     1921 ttttgctggt tcacaggtta gtctggaaga cttcctagcc ttgctccatt ctggaatgag
     1981 tttgtcccaa taccgtacca ttccagcaac agtggacact gttctggtgc agagttacga
     2041 tttgattgca ccattgactg ctgactttgt ctatgctatt ggactaactc aggacaattt
     2101 accaaaaatt tctcaaaaca ccagtcttct gacagatgaa gaaaggcaaa acctaaacca
     2161 agcgaccgaa gaaggcgttc aattactgat tgccagcagt gaaaatctca agaaaaatcg
     2221 ctacactatg ctttccttgg tcaattctgc tcgtaagcag ttgttcttgt cggctccaag
     2281 cctttttaac gaaagtgaaa gtaaggaatc tgcctatctt caagagttga tccattttgg
     2341 atttaggcgg agagagaaga ggatgaatca caaaggactg tctaaggagg atatggggtc
     2401 ctatcacagt cttttgtcta gtctggttgc ctatcaccag cagggtgaga tgagcgatac
     2461 tgagcaagat ttgacttttg tcaaggttct gtcgcgtgtc ataggtaaaa aactagatca
     2521 gcaaggtctg gaaaatccag ccatcccaat cagtccaagc agcaagacct tagccaagga
     2581 caccttgcaa gctctctatc ctgccaaaca ggagttttac ctgtctacgt cgggtttgac
     2641 agagttttat cgcaatgaat acagttattt cctacgctac gttttaggct tgcaggagga
     2701 attacgtttg catcctgatg cccgtagtca cgggaatttc ttgcatcgta tctttgaacg
     2761 cgccttacag ttgcctaatg aagattcctt tgaccaacgt ctagaacaag ctattcaaga
     2821 aaccagtcaa gaacgcgaat ttgaagctat ttatcaagaa agtttggaag cccagtttac
     2881 caaggaagtt ttgcttgatg ttgcacggac gactggacat attctccgac acaatccagc
     2941 catcgaaacc atcaaagaag aagcaaattt tggtggaaaa gaccaagcct ttattcaatt
     3001 agacaatgga cgcagtgtct ttgtacgagg caaggtggac cggattgacc gtttgaaagc
     3061 taatggagcg ataggagtag tagactacaa atccagtctg actcagttcc agtttcctca
     3121 tttctttaat gggctcaatt ctcagttacc aacctatctt gctgccctaa aaagagaagg
     3181 ggagcagaac tttttcggcg ccatgtactt ggaaatggct gaacctgtcc aatctctgat
     3241 ggcggtaaaa agtcttgcag gagcagtggt agaagccagc aaatctatga aataccaagg
     3301 gctcttcttg gaaaaagaaa gcagttattt aggcgaattt tataacaaaa acaaggctaa
     3361 tcaactgaca gatgaggaat ttcagctcct actggactac aatgcctatc tttacaagaa
     3421 agctgctgag aagattttag caggccggtt cgccatcaat ccttatactg aaaatggcag
     3481 aagcattgcc ccatacgtcc agcaacatca ggctattaca ggctttgaag ccaattacca
     3541 tctgggccaa gcccgtttcc taaaaaagtt ggacctagct gatagcaagc gtctggtcgg
     3601 agaaaaactc aagcaagctt ggcttgaaaa aataagagag gagttgaatc gatgaagctt
     3661 attccctttt taagtgagga ggagattcaa aaactgcaag aagcagaagc aaattcgagc
     3721 aaggaacaga agaaaactgc cgagcaaatc gaagctatct acacttctgg ccagaatatc
     3781 ctggtctcag catcggctgg ttctggaaag acctttgtca tggcagagcg cattctggac
     3841 caattggcgc gtggtgtcga aatttctcaa ctctttatct caacctttac cgtcaaggct
     3901 gcaactgaac ttaaagaacg tttagagaaa aaaatcagca agaaaatcca agaaacagat
     3961 gatgtcgagc tcaaacaaca cttgggtcgc cagttggcag acctacccaa cgctgccatc
     4021 ggaaccatgg actctttcac acaaaaattc cttggcaaac atggttatct gcttgatatt
     4081 gcacctaatt tccgtatttt acaaaaccaa agcgagcaac ttcttctcga aaacgaagtc
     4141 tttcatgagg tctttgaagc gcattaccaa ggtaaacaga aagagacctt tagtcatttg
     4201 ctgaaaaact ttgctgggcg tggcaaggac gaacggggtc tgcgccagca ggtctataaa
     4261 atctatgact tcctccaatc caccagcaat tctcaaaagt ggctgagtga ctctttcctc
     4321 aaaggctttg agaaagctga ttttaccagt gaaaaagaaa aactgactga gcaaatcaaa
     4381 caagcccttt gggatttgga aagctttttc cgttaccatc tggataacga tgccaaggag
     4441 tttgcaaagg ctgcctattt agaaaatgtt cagttaattc tggatgaaat ttgctcccta
     4501 aatcaggagt ccgatagtca ggcttatcag tcagtgcttg cgcgtgttgt cgccatctct
     4561 aaggagaaaa acggtcgagc tctgactaat gccagccgta aggctgattt gaagcccctg
     4621 gctgatgcct acaacgaaga gagaaagacc cagtttacta aactaggaca attatcagac
     4681 cagatagcga ttctcgacta tcaagaacgt tatcatggag acacttggaa actagctaaa
     4741 accttccaat ctttcatgag cgattttgta gaggcttatc gtcagagaaa acgacaggaa
     4801 aatgcctttg aattcgctga tatcagccat tacaccattg agattttaga aaatttccca
     4861 caagttcgtg agtcttatca ggagcgcttc catgaagtca tggtcgatga gtatcaggat
     4921 accaaccata ttcaagaacg gatgctggaa ttgttgtcta atggccacaa tcgctttatg
     4981 gtgggagata tcaagcaatc catctatcgt ttccgtcagg cagacccgca gattttcaat
     5041 gagaaattcc aacgctatgc gcaaaatcct caagaaggca ggctcattct cctcaaggaa
     5101 aatttccgta gtagttcaga agtgctgtca acaaccaatg atgtctttga acgtctcatg
     5161 gaccaagagg tcggcgaaat caactatgat aacatgcacc agcttgtttt tgccaatacc
     5221 aaactgactc ccaatccaga caacaaggca gaatttctcc tctacgacaa ggacgataca
     5281 ggtgaggaag aagagagtca aacagaaacg aaactaacag gcgaaatgcg cttagttatc
     5341 aaggagattc tgaaacttca tcaagaaaaa ggtgttgcct ttaaggaaat tgcccttctg
     5401 acctccagcc gcagtcgtaa tgaccagatt ctcctcgccc tgtctgagta cggaattcct
     5461 gtcaaaactg acggagagca aaacaattat ctccaatccc tagaagtgca agtcatgcta
     5521 gacactcttc gtgtcattca caatcccctg caagactacg ccttggttgc ccttatgaag
     5581 tctccaatgt ttggttttga tgaggatgag ctagcacgtt tgtcccttca gaaagcagag
     5641 gataaagtcc acgaaaatct ctatgagaaa ctggtcaatg cacaaaaaat ggcaagtagt
     5701 caaaaaggtt tgattcacac agctctagct gaaaaactaa agcaattcat ggatatccta
     5761 gcttcttggc gcttgtatgc caaaacccac tctctctatg acttgatttg gaagatttac
     5821 aacgaccgtt tttattatga ctatgttggg gctttgccga atggtcctgc taggcaggcc
     5881 aatctctatg ccctagcact gcgtgctgat caatttgaaa agagcaattt caaaggtttg
     5941 tcgcgtttta ttcgtatgat tgaccaagtc ttagaagccc agcacgattt ggcaagcgtg
     6001 gccgtcgcac cgccaaaaga tgcagtagag ctcatgacca tccacaagag taaggggctg
     6061 gagtttcctt acgtctttat cctcaatatg gatcaagatt tcaacaagca agactctatg
     6121 tcagaagtca ttctcagtcg tcagaatggt cttggtgtca aatatattgc caagatggag
     6181 acaggggcag tagaagacca ctatcctaaa accatcaaac tctccattcc tagcctgacc
     6241 tataggcaga atgaagagga attacagcta gcaagctatt ctgagcagat gcgtttgctg
     6301 tatgttgcta tgacgcgggc tgagaaaaag ctctatcttg tcggcaaggg ttctcgtgaa
     6361 aagctggaag ccaagcaata cccagcagcc aaaaatggga aactaaatag caatactaga
     6421 ctgcaagcac ggaatttcca agattggctt tgggctatca gtaaagtgtt tactaaggac
     6481 aagctcaact ttagttatcg ttttattggc gaagatcagt tgaccagaga agctatcgga
     6541 gagttggaaa ccaagagtcc tctccaagat agctcccaag cagacaatcg tcagtcagat
     6601 accatcaaag aagctctgaa aatgctgaag gaggtggaag tttataatac tcttcaccgc
     6661 gcagctattg aacttcctag tgttcaaacc ccaagtcaaa tcaagaaatt ctacgaacca
     6721 gttatggata tggaaggtgt cgagattgct ggtcaaggtc agtcagtagg caagaaaatc
     6781 agcttcgatt tgccagattt ttcaacaaaa gaaaaggtaa ctggagctga gattggtagt
     6841 gctactcacg aactcatgca gagaattgac ctcagccagc aactaaccct tgctagccta
     6901 acagaaacac tcaaacaagt tcaaactagc caagctgtca gagacaagat caatcttgat
     6961 aaaattcttg ctttctttga cacagtactc ggtcaggaaa ttcttgctaa taccgaccat
     7021 ctctatcgcg agcaaccttt ctccatgctc aaacgagacc aaaagagtca ggaagacttt
     7081 gttgtccgtg gtatccttga tggctatctg ctttacaaaa acaaaattgt tctgttcgac
     7141 tacaagacag accgctatga tgaaccaagt caactcgtag accgctatcg tggtcagtta
     7201 gctctatacg aagaggcttt atcacgagcc tattcgattg aaaatattga aaaatacttg
     7261 attttactcg gtaaagacga ggctcaagtt gtaaaagtat aacttatact ctttgaaaat
     7321 ctcttcaaac cacgtcagct tcgccttgct gtatatatgg ttactgactt cgtcagttct
     7381 atccacaacc tcaaaacagt gttttgagct gactgcggct agctttctag tttgctcttt
     7441 gatttttatt gagtattaga aaggagacct catgacactt ccagttagaa aatccctgca
     7501 cgatgcagtt ttacaggctt cgaaagcgga tacttgggaa caagctacca aggaatggaa
     7561 tgaagtttcc ttgattttta acggtatcgg ccgtagcaat tgtgtctgtg gaaatgccat
     7621 caaatacgct tatgaactct ttaacggtgt cacaggccaa cgcctctttc caattggtag
     7681 cgactgtgtt cgtcattttc atcgattgtc ccttgaccag caattggaag aggaagaaaa
     7741 actgctcaga aaggttgaaa atctaaccag aaaagctcag aaaaaggaaa aaatcaaggt
     7801 caataaaagt gactttgacg agcgacttct aaaatggctc tgggaaaaag gtgttttcaa
     7861 acccaatcgt ggcaatcaat ttgcgcctga gagagactac cagcttttcc tagaagtctt
     7921 tcagggagga agttggacca aggcggaacc aaagaaaaag gctcggatgg aagaagtcct
     7981 tgaaaagtgt atcaaaccct ttttacttgg gaaatcggat gaccaactct accttgtcaa
     8041 gctaggcaag gagaaaattg actacgaaca agaactccgt atccaggcag agaaagaacg
     8101 caagaagagg gataaaatcg ccaagcaata tgcagacaat ctggttctag ccatgggacc
     8161 cgcagagcgt gcttatcaag attactttgg ctttacagag accctgactc aagaagaacg
     8221 caagtgggaa aaaattcttt ttggtaaaaa tagagcagaa cgggctatca aggccaaaca
     8281 ataccaaaaa gagctggaaa aagaccaacg aattgccagt caggatccaa ttgaaagaaa
     8341 acagaagcag acttggctcc tcaattccta ttttcgtgag cttcctgaag aaaaagctcg
     8401 attttctagg ctcttattag aatatcgaaa aagtggtgaa gtaccctttt caactgaata
     8461 cctgtcagat catctcatcg actttttcta taaaatgaaa gcctttgaat ttgaaatcgc
     8521 accagaacaa gtccgagatt ttctaaaaaa aagcctgcag gaagaccatc gctcatcagc
     8581 acaaggaagc tggatagaag gaattctcct caactgcctc aaaccatttt tagaacgatt
     8641 agtgatatga gtaacaccta ccgtgtaaat ttcatggtag gtgttattgt accccaaaat
     8701 aatataaaac aaagtatgaa agcgcatctc aattttaaga cttttttgta aattaagagt
     8761 ataattaagg tatactgcct tttctataga taatagataa tacactaata taataaaggt
     8821 ctttgtaaca tatataaatt ttatttcaag gaggaataat ggaaaagtat tttggtgaaa
     8881 aacaagagcg tttttcattt agaaaattat cagtaggact tgtatctgca acgatttcaa
     8941 gtttattttt tatgtctgta ttagctagtt catctgtgga tgctcaagaa actgcgggag
     9001 ttcactataa atatgtggca gattcagagc tatcatcaga agaaaagaag cagcttgtct
     9061 atgatattcc gacatacgtg gagaatgatg atgaaactta ttatcttgtt tataagttaa
     9121 attctcaaaa tcaactggcg gaattaccaa atactggaag caagaatgag aggcaagccc
     9181 tagttgctgg tgctagctta gctgctctgg gaattttaat ttttgctgtt tccaagaaaa
     9241 aggttaagaa taaaacggta ttacatttag tattggttgc gggaatagga aatggtgtct
     9301 tagtttcagt ccatgcttta gaaaatcatc ttttgctaaa ttacaatacg gactatgaat
     9361 tgacctctgg agaaaaatta cctcttccta aagagatttc aggttacact tatattggat
     9421 atatcaaaga gggaaaaacg acttctgatt ttgaagtaag taatcaagaa aaatcagcag
     9481 ccactcctac aaaacaacaa aaggtggatt ataatgttac accaaatttt gtagaccatc
     9541 catcaacagt acaagctatt caggaacaaa cacctgtttc ttcaactaag ccgacagaag
     9601 ttcaagtagt tgaaaaacct ttctctacta aattaatcaa tccaagaaaa gaagagaaac
     9661 aatcttcaga ttctcaagaa caattagccg aacataagaa tctagaaacg aagaaagagg
     9721 agaagatttc tccaaaagaa aagactgggg taaatacatt aaatccacag gatgaagttt
     9781 tatcaggtca attgaacaaa cctgaactct tatatcgtga ggaaactata gagacaaaaa
     9841 tagattttca agaagaaatt caagaaaatc ctgatttagc tgaaggaact gtaagagtaa
     9901 aacaagaagg taaattaggt aagaaagttg aaatcgtcag aatattctct gtaaacaagg
     9961 aagaagtttc gcgagaaatt gtttcaactt caacgactgc gcctagtcca agaatagtcg
    10021 aaaaaggtac taaaaaaact caagttataa aggaacaacc tgagactggt gtagaacata
    10081 aggacgtaca gtctggagct attgttgaac ccgcaattca gcctgagttg cccgaagcag
    10141 tagtaagtga taaaggcgta ccagaagttc aaccagcgtt atcggaagca gtcgtaaccg
    10201 acaaaggtga gcccgctgtc caacctgaat tacccgaagc tgtagtaagt gataaaggcg
    10261 taccagaagt tcaaccagcg ttatcggaag cagtcgtaac cgacaaaggt gagactgagg
    10321 ttcaaccaga gtcgtcagat actgtggtaa gtgataaagg tgaacctaaa caggtagcac
    10381 cgcttccaga atataagggt aatattgagc aagtaaaacc tgaaactccg gttgagaaga
    10441 ccaaagaaca aggtccagaa aaaactgaag aagttccagt aaaaccaaca gaagaaacac
    10501 cagtaaatcc aaatgaaggt actacagaag gaacctcaat tcaaggagca gaaaatccag
    10561 ttcaacctgc agaagaatca acaacgaatt cagagaaagt atcaccagat acatctagcg
    10621 aaaatactgg ggaagtatcc aataaaccta gtgattcaaa accaccagtt gaagaatcaa
    10681 atcaaccaga aaattcaggt aatacaacat cagagaatgg acaaacagaa ccagaaccat
    10741 caaacggaaa ttcaactgag aatgtttcaa ccaaatcaaa cacatccaat tcaaatggaa
    10801 acgaagaaat taaacaagaa aatgaactag accccgataa aaaggtagaa gatccagaga
    10861 aaacacttga attaagaaat gtttccgacc tagagttata cagtttgtca aatggtactt
    10921 ataaacaaca catttcgtta gaacaagttc caagcaatcc aaatagctac tttgttaaag
    10981 tgaaatcttc ttcattcaaa gatgtatacc taccagtagc atcaatatca gaggaaagaa
    11041 aaaatgataa aatcctttat aaaatcacag caaaagtaga gaagcttcag caggagatag
    11101 aaagcagata taaagataat tttaccttct atctagctaa gaagggaaca gaagaaacaa
    11161 caaactttac ttcctttagt aatctggtca aagctataaa ccaaaatctc tctggaacct
    11221 atcatttagg agctagcctg aatgctaacg aagtggagct tagtactgat gataaatcct
    11281 atatcaaggg aacctttact ggtcagttga ttggtgaaaa agatggtaag cattatgcta
    11341 tttacaactt gaaaaagcct ctttttgaaa gcttgagagg ggccacaata gaaaagttga
    11401 gtctgaaaaa tgtctctatt tcagggaaag atgatatcgg ttcactggca aatgaagctc
    11461 agaataacac aaaaattaag caagttcatg tggatggtgt acttgccggt gaacgtggta
    11521 tcggtggttt gttggctaag gcagatcaat caagcatcac agagagtagt ttcaagggaa
    11581 gaattgtcaa tacctatgaa acaaccgctt cctataatat cggtggcctg gtcggtcact
    11641 tgacaggaag caaagcttca ctgactaagt caaaagcgac agtggtcatt tcatcaaata
    11701 caaatagttc tgaccagacc gttggaggta tcgctggtct tgtagacaaa gatgcgcata
    11761 ttcagaatag ctattctgaa ggggatatta ataatagtca acgttttgga aaagttgctg
    11821 gtatagcagg taacttatgg gatcgtgaat caaatagtga aaatcatgct ggaagattga
    11881 ctaatgtgct tagtgatgtc aatgtaacta atggaaatgc cattagtggt taccattata
    11941 atggaatgaa aattactgat gcatttagta ataaagcgaa taaagttttc aatgtcactt
    12001 tagagaagga tgaggtcgtc agcaaagaat cctttgagga aagaggaaca atgctagatg
    12061 cttctcaaat tgcaagcaaa aaagcagaaa tcaatcttct cactccacca atagtgaaac
    12121 ccctctcaac aagcggtaag aaagacagtg atttttctaa gatagcccat tatcaagcca
    12181 accgtgcttt ggtttataag aacattgaaa aattgttacc tttctataac aaggcgacca
    12241 tcgtgaaata cggaaacctg gttaaggaga acagtatctt atatcaaaaa gaactcttgt
    12301 ctgcagttat gatgaaggat gaccaagtaa tcacagatat tatttccaac aaacagactg
    12361 caaacaaact cttgcttcac tacaaggacc attcatctga aaagtttgat ctcaggtacc
    12421 aggctgattt tgctaagtta gcagaatata gtctaggaga tactggtctt ctctatacgc
    12481 caaaccaatt cttgtatgac caagactcta tcatcaatca agttttacct gaattacagc
    12541 aggttgccta cgattcagaa gctatcagaa agacactcgg aatttctcca gaggtcaagc
    12601 aaactgagct ctatatggaa gaccagttta ccaaaacaaa gcaagatttg gcaaacagtt
    12661 tgaaaaaact cttgtctgca gatgctggac ttgctggtga caacccagtt accagaggct
    12721 atcttgtaga taaaatcaag aacaataagg aagccttact actcggttta acttatttag
    12781 aacgttggta taactttagc tatggtcaag tgaatgtcaa aaacctagtt atgtatcatc
    12841 tggacttctt tggtaaagga aatacctcac cattagatac tctgattgag ttaggtaaat
    12901 ctggctttaa caatcttctt gctaaaaaca atgtcgatac ttatgctatc agtcttgcca
    12961 gccatcatgg aacgacagat ttgtttagca cgttggaaaa ttaccgaaaa gtctttctac
    13021 cagacaaaac caataatgac tggtttaaat cacagactaa ggcttacatt gtcgaagaaa
    13081 aatccaatat cgaagaggtg aaaacgaagc aaggactagt tggtactaag tattctattg
    13141 gtgtctatga tcgaatcact agcgacagct ggaaataccg taatatggta ctacctctac
    13201 ttaccttgcc agaaagatcc gtatttgtca tttcaaccat atctagtcta ggttttggtg
    13261 cttatgatcg ctatcgtaat aaagaacatc aagcaaatgg tgatcttaat agctttgttg
    13321 aaaagagtgc tcacgaaaca gcagagcgtc aacgagatca ctatgattat tggtatcgta
    13381 ttctagatga aaaagggcgt gaaaagcttt atcgaaatat cttgctttat gatgcctata
    13441 aatttggaac tgatcatact gaaggaaagg ctacagaagt agcaaatttt gataatccaa
    13501 atcctgcaat gaaacatttc tttggacctg ttggaaataa ggttggacat aatggacatg
    13561 gtgcttatgc tacagaggat gccgtttatt atatgggtta tcgtatgttg gacaaggacg
    13621 gcgccattac ttatacgcat gagatgacac atgactcaga tcaggacatt tatcttggag
    13681 gttatggaag aagaagtgga cttggacctg agttctttgc taaaggctta ctacaagcac
    13741 cagaccaacc aagtgatgca accattacca tcaactctat cttgaaacat aaaacatcag
    13801 atagtacaga aggtcagcga ttgcaagtac ttgatccaac tacaagattt aatgacgcag
    13861 cagatcttca gaactacgtc cacaatatgt ttgatgtcgt ttacatgttg gaatatctcg
    13921 aagggcaatc tatcgtgaaa cagttagatg cttatcagaa aatgacggcc ctgagaaaaa
    13981 tcgagaataa atacgtgaaa gatcctgcag atggaaatga tgtttatgct actaatgttg
    14041 tgaaaaattt gactgaagat gaagctaaaa aattgacgag ctttgatagt ttgattgaca
    14101 ataacattct ttcggctcgt gagtataagg ctggcactta tgagagaaat ggctacttta
    14161 ctataaaact ctttgcacca atcttttcag cattgagcag tgagaaagga actccaggcg
    14221 accttatggg acgtcgtata gcctatgaac tactagctgc taaaggcttt aaagatggta
    14281 tggtaccata tatctcaaat caatacgaag aagatgctaa acaacaaggg caaactatca
    14341 atctttatgg taaagaacgg ggcttggtga ccgatgagct tgttttgaaa aaggtatttg
    14401 atggtaagta taaaacttgg gcagaattta agacagctat gtaccaagaa cgggtggatc
    14461 agtttggaaa cttgaagcag gtgaccttta aagatccgac aaaacgatgg ccaagctatg
    14521 gcacaaagac tatcaataat gtggatgaat tgcagaaact aatggatgaa gctgttttgc
    14581 aggatgctac aggtacacgt tggagtaatt ataatccaga aatagacagt gcagttcata
    14641 agttgaagag agcaatcttt aaagcctatc ttgctcaaac caatgatttt agaagttcaa
    14701 tttttgagaa taaaaaatag tgtttactat taggaaataa agtttaaaaa ggtgatgaag
    14761 aacaaaccaa gattcaagca ggaattccta ctgataatga agtaagttat gctcttattt
    14821 atcagcagga aactcttcct gcaacaggtt catcaacttc tgcgcttaca gctttaggcc
    14881 tattagctgt tggtagttta gttcttttgg ttcataatat gacgggaaca gttttttgct
    14941 ccctctgaaa agtcatcatt tgatggcttt tttctatata gggtaaaaga tagggtaaaa
    15001 ggctatcatc ggacaaaata aagaaggcat gatataatat aaagtagatt tctatgtcat
    15061 aaaacaagaa ctgtttggac atcatccatt tgaagactct ctatgttcaa actatagtaa
    15121 aataaaatag gggatctaaa tccttgctac gaaaggaaaa aactcaatgg ctactattca
    15181 atggtttcct ggtcacatgt ctaaagcgcg tcgacaggtg caggaaaatt taaaatttgt
    15241 tgattttgtg acgattttag tagatgcacg cttgcctcta tctagtcaaa atcctatgtt
    15301 gaccaagatt gttggtgata aaccaaaact cttgatttta aacaaggccg acttggctga
    15361 tccagcaatg accaaggaat ggcgtcagta ttttgaatca caagaaatcc agacgctagc
    15421 tatcaactcc aaagagcaag tgactgtaaa agttgtaaca gatgcggcca agaagctcat
    15481 ggctgataag attgctcgcc agaaagaacg tgggattcag attgaaacct tgcgtaccat
    15541 gattatcggg attccaaacg ctggtaaatc cactctgatg aaccgtttgg ctggtaaaaa
    15601 gattgctgtt gttggaaaca agccaggggt cacaaaaggt caacaatggc ttaaaaccaa
    15661 taaagatctg gaaatcttgg atacaccggg gattctctgg cctaagtttg aggatgaaac
    15721 tgttgcactt aagttggcat tgactggagc tatcaaggat cagttgcttc ctatggatga
    15781 ggttaccatt tttggtatca attatttcaa agaacattat ccagaaaagc tggctgaacg
    15841 cttcaaacaa atgaaaattg aagaagaagc gcctgtgatt attatggata tgacccgcgc
    15901 cctcggtttc cgtgatgact atgaccgttt ttacagtctc ttcgtgaagg aagtccgtga
    15961 tggcaaactc ggtaactata ccttagatac attggaagac ctcgatggca acgattaaag
    16021 aaatcaaaga actccttgtg acagtcaagg agttagaaag ccctattttt ttagagcttg
    16081 aaaaggataa tcgctcagga gttcaaaagg aaatcagcaa gcgtaaaaga gccattcaag
    16141 ctgaattaga tgaaaatttg cgcttggaat ccatgctttc ttatgaaaaa gaactttata
    16201 agcaaggatt gaccttaatt gtaggtattg atgaggttgg tcgtggtcct cttgctggtc
    16261 ctgtagtcgc tgcggccgtc attttaccta aaaattgtaa gattaaaggt ctcaacgaca
    16321 gcaagaaaat tcctaaaaag aaacatctgg agattttcca agccgttcaa gaccaagcct
    16381 tgtcgattgg aattggtatc atagataatc aggtcatcga ccaagtcaac atctatgaag
    16441 caaccaaact agccatgcaa gaagcaatct cccagctcag ccctcaacca gagcaccttt
    16501 tgattgatgc catgaaactg gacttgccca tttcacaaac ctccattatc aaaggagatg
    16561 ccaactccct ctctatcgca gcagcatcta tagtagccaa ggtaacacgt gatgaattga
    16621 tgaaagaata cgatcagcag ttccctggct atgatttcgc tactaatgca ggatatggca
    16681 cagctaaaca tctggaaggc ctcacaaaac taggagttac cccaattcac cgaaccagct
    16741 ttgaacccgt taaatcactg gttttaggta aaaaagaaag ttaattgaaa ggaaatacca
    16801 tggaggaaca gtcggaaata gtccgttcta agaaagaatt cgcctttgca tccagcacta
    16861 tactatccca agttggtcga ggaatcattg tcggcctcat cgttggaatt atcgtcggat
    16921 cctttcgttt cttaattgaa aagggcttcc acatgataca aggagtttat caagatcaag
    16981 ggtacttagt gcgcaatctt tttgtactgg ttttgtttta tatactcatc tgttggctca
    17041 gtgccaaact aacacggtca gaaaaagata ttaaaggctc aggaattcct caagtcgaag
    17101 ccgaactgaa aggcctcatg tccctcaact ggtggggcat tctttggaaa aaatatgtgc
    17161 taggtattct tgctattgcc agtggactca tgctgggtcg agagggaccc agtattcaac
    17221 ttggagcagt tggtggtaaa ggaattgcca agtggctcaa atccagtcca gtagaggaac
    17281 gttccttgat tgccagtgga gctgcagcag gtttagccgc agcctttaat gctcctattg
    17341 cagcacttct ctttgttgta gaagaagtct atcaccattt ttcgcgcttt ttctgggtct
    17401 caactctagc agccagcatc gtagcaaact ttgtgtctct actcatgttc ggtttgacac
    17461 cagtattgga tatgccagat aacattcctc ccatgaccct agatcagtat tggatatatc
    17521 tcgtcatggg aattttcctt ggattttcag gttttctcta tgagaaagct gcattaaacg
    17581 ttggaagagt ttatgacttg attggtcaaa aaatccattt ggatagggct tattatccca
    17641 tcttggcttt tatccttatc ataccagtcg gaatcttctt acctcaaatc attggtggcg
    17701 gaaatcagct tgtcctttct ttaactgaac aaaattttag tttccaagtt ttattagctt
    17761 actttttaat ccgctttatt tggagtatga ttagctatgg aagtggactg ccaggaggaa
    17821 ttttcctccc cattttagct cttggttctt tgcttggtgc cttagttggt gttatctgtg
    17881 tcaatcttgg acttgtcagt caagagcaat tccctatatt tgtcattcta ggaatgagtg
    17941 gctattttgg agccatatca aaagctccct taaccgctat gatcctcgta actgagatgg
    18001 taggagatat tcgcaacctt atgccacttg gtcttgtcac tcttgtttct tatattatca
    18061 tggatttgct caaaggtacg ccagtctatg aagccatgct ggaaaaaatg cttccagaag
    18121 aagtatctag cgaaggagaa gttacactta tcgaaatacc agtttctgat aaaattgctg
    18181 ggaaacaagt tcatgaactc aacttaccac acaacgtcct catcacaact caagtccata
    18241 atggcaagag ccaaacagtt aacggctcaa ccagaatgta tctgggtgat atgattcacc
    18301 tggttattcc aaaaagtgaa attggaaaag tcaaagattt gttgttgtag tatgatcatt
    18361 tacataattt atgttatgta aatgatcggt ttgatttatt tagaaaaccg attctcagaa
    18421 atgagatcgg ttatttttta ctgatgagga attttacata taaataattg aactttatta
    18481 aaaataagac ta
//
LOCUS       DAVKBC010000036        18422 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVKBC010000036 DAVKBC010000000
VERSION     DAVKBC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18422
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.036"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            15..299
                     /locus_tag="VWX64_001525"
     CDS             15..299
                     /locus_tag="VWX64_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190974.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            292..530
                     /locus_tag="VWX64_001526"
                     /pseudo
     CDS             292..530
                     /locus_tag="VWX64_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            626..844
                     /locus_tag="VWX64_001527"
     CDS             626..844
                     /locus_tag="VWX64_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190975.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(1216..3540)
                     /gene="pflB"
                     /locus_tag="VWX64_001528"
     CDS             complement(1216..3540)
                     /gene="pflB"
                     /locus_tag="VWX64_001528"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU9190976.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            3889..4950
                     /gene="dinB"
                     /locus_tag="VWX64_001529"
     CDS             3889..4950
                     /gene="dinB"
                     /locus_tag="VWX64_001529"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU9190977.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMNISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(5097..5942)
                     /locus_tag="VWX64_001530"
     CDS             complement(5097..5942)
                     /locus_tag="VWX64_001530"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU9190978.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            6198..6979
                     /locus_tag="VWX64_001531"
                     /pseudo
     CDS             6198..6979
                     /locus_tag="VWX64_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7358..9247)
                     /locus_tag="VWX64_001532"
     CDS             complement(7358..9247)
                     /locus_tag="VWX64_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU9190979.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPMTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            9385..10950
                     /locus_tag="VWX64_001533"
     CDS             9385..10950
                     /locus_tag="VWX64_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9190980.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWGLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            10950..11690
                     /locus_tag="VWX64_001534"
     CDS             10950..11690
                     /locus_tag="VWX64_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9190981.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFSNPKEDRTKEFLQRYLK"
     gene            complement(11799..12014)
                     /locus_tag="VWX64_001535"
     CDS             complement(11799..12014)
                     /locus_tag="VWX64_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190982.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(12885..14135)
                     /gene="ilvA"
                     /locus_tag="VWX64_001536"
     CDS             complement(12885..14135)
                     /gene="ilvA"
                     /locus_tag="VWX64_001536"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU9190983.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(14185..14541)
                     /locus_tag="VWX64_001537"
     CDS             complement(14185..14541)
                     /locus_tag="VWX64_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU9190984.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(14779..15015)
                     /locus_tag="VWX64_001538"
     CDS             complement(14779..15015)
                     /locus_tag="VWX64_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9190985.1"
                     /translation="MLADQNKADWSYDENTVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHFPFERAGATKSARYIAKWILRNKKH"
     gene            complement(15122..16144)
                     /gene="ilvC"
                     /locus_tag="VWX64_001539"
     CDS             complement(15122..16144)
                     /gene="ilvC"
                     /locus_tag="VWX64_001539"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU9190986.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVTEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(16210..16686)
                     /gene="ilvN"
                     /locus_tag="VWX64_001540"
     CDS             complement(16210..16686)
                     /gene="ilvN"
                     /locus_tag="VWX64_001540"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU9190987.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(16679..18379)
                     /locus_tag="VWX64_001541"
     CDS             complement(16679..18379)
                     /locus_tag="VWX64_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU9190988.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
BASE COUNT         5663 a         3947 c         3341 g         5471 t
ORIGIN      
        1 ataggaggaa gacaatggat tggtacgatt atatgataca ggcatccaaa caatcacaat
       61 tcaacgcaag ccattggttt cgctatttgc gaaaagttat ttttgaagac tattcttatt
      121 taacaaacca agatgtagaa aagttgctag actccaaaga actaacccgt tttcaaaaaa
      181 ttagcttgaa gtatgccttt caagagcata ctccaactca taaatatgtg atttcattaa
      241 ataaacctgc taagttaacc aatgttcaaa aattgatgga gaaatacaaa catggataaa
      301 atgaaaccgg tcttccaagc cctaaataag aaattaattc aggaaaatct gactttaaca
      361 attatggtta tgtcttagaa tatcatggtt tacgtgccac acaagatgtt gatgcttttt
      421 atgaccaaaa tcagaaaatc aatgaaatta ttgctcgtgt aggaaaacag tttaatctta
      481 acatccacga agagttatgg ctcaacaatc atgttgcaaa gcaaatatga acaaacaacc
      541 tcccttaagt ttatgcgaat ccttgtactc atttgagaat ctgaccgttt tagtagtccc
      601 tattgagtat gtgttaggaa tgaagatgat gagtatcaga gagcaggatt tgcaagatat
      661 tggtgcaatt attaaataca aaaactttca ttcaccattc gataccttta aatatttaaa
      721 agacatggga tttgatacta ttgacctctc tgttctatta gaaggtttta gttatgctta
      781 tggtatggat tggttagaaa aattttttaa agaaaatcaa gataaacttc gcgaatttta
      841 ttaacagtat caaacaagat gattgtcaat tagccagtcg tcttattttt atgatgaaat
      901 gaaatgaaat aaaatcggaa caaatcactt agagaattcc agtcaatttc tagcactgtt
      961 tgagccgttt cagcggacta tagtaaaatg aaataagaat aggacaaatc gatcaggaca
     1021 gtcaaatcga tttctaagaa tgttttagaa gtaaaggtgt actattctag tttcaatcta
     1081 ttatatttca gattcggtcc actattcctt cccaaaaaca ttgcatattg cgccgaagga
     1141 attgctcata ctatcccaag cacaaaaccc tcagtcgttt gaccgagggt tcctttttat
     1201 tattcaagaa cttgattagc tcaatgcatc caaggcgtca tccattgaaa gaacttcgtg
     1261 gaagacacgt tgtgtcaatt cagttttttg ttctggagtg aggtatttag tgtttacaca
     1321 gtatccagag atacgtacga taacgtcttc gcctgacatg attttttcgt aaacatcgtt
     1381 caagtccata acgttcaagt taacgtgttg tccaccgttt tcgaagtaac catcaaggat
     1441 tgttaccaag ttatcaactt gttcatcacg agtcttacca agagcgcgag gtgatacttg
     1501 tgtagtcaat gagataccgt cagctgcata actaaagtca aggctagaaa gtgagttcaa
     1561 gttttgcaac caaccacctt tagctttgtt agatgggtta gcacctggtg agaagaattc
     1621 aagtttagac aagttcacag aaccatcttc gttgaggtat acacctttgt gaactggtga
     1681 gttaccagtt tgtttagagt aagcaacgtt agatgtgatt gtcaaaagtg atactgtagc
     1741 ttctgcatct ttgtatagtt tgtggctacg tagacgagtt gtgtaagctt cgatcaacca
     1801 ttctgccaat tcgtttgaac gtgggtcatc ttcaccccag cgtgggtagt caccgattgt
     1861 ttcgtaatcg tagatgtagc catcttcgtc acggattggt ttaactgtag cgtatttgat
     1921 agctgacaat gtatcaacag tgttagcaaa tccacagata ccgaatccca tgttggcacg
     1981 ttgtttagtt ggcaagaagg ccatttgaac agcttcgtag ttgtacctat cagtcatgta
     2041 gtggatgatg ttcaaggcat ctacgtaagt gtcagtcaac cagtcaagag atttttcaaa
     2101 gttcgcttta actgattcaa attcaagaac ttcgtcacgg attggttcga tatcaaatac
     2161 tttgtagtct ttgtgaacat cgtcgtaacc accattcaaa ccagtaagaa gggctttaag
     2221 aacgtttaca cgagcaccga agtactggat gttgtggcgt tgttcttcat tttctggatc
     2281 aagtggagac acacagcatg agatacagct catttcacca tatccgtctt tagccattgt
     2341 tgttacacct tcgtattgga tagaagagtg tttgtggctc atgtgcatac agtagcgacg
     2401 gaagttgtat ggcaatttgt cagtccaaag aactgtcaag tttggttctg gtgagttacc
     2461 gatgttgtca agagtgttca agaaacggta gtccatctta gtaacacggt gacgaccgtc
     2521 gttacccata ccagccatag aagttgtgat aaaggttggg tcacctgagt acaattggtc
     2581 ataagctttg gtacgagcaa atttaactgt acgaagtttc ataacgaaat catcaacgaa
     2641 ttcttggatt tctgattcag taaatgtacc acgagcaagg tcacgttctg caaagatgtc
     2701 caatacgatt ggtacacgac ctagagatgt agcagcaccg ttaatcacac ggcagacagc
     2761 catgaaagca atgttaaccc attggattgc ttctttcacg ttcatcgctg gtttgcgaac
     2821 atcaaccccg taaaggtcac ccaggcgaac aacttgttgc aatgcttggt attgaaggtt
     2881 tacttcttca cgaagacgga ttgtttcttc atcgatttct ttgattgcat tccagtcgtt
     2941 tactttttct tgcatcaagt agtctgcacc gtaaagagca agacgtgcgt aaacaccgat
     3001 gatacgtccg cgtgagtatg catctggaag accagttaca gtgtgtgcat gacgagcgcg
     3061 acgaatattt gaagtgtagg cacggaaaat accgtcgtta actgttgtta catatttagt
     3121 gaagatttcg tgaacagctg ggtctggttc gtatccattt tcttttaaag tagtttcagc
     3181 catacggata ccaccttttg gcatgaagtt caatttgaag agttcatcat tttggatacc
     3241 aaagataact tcattttctt tgtcgataaa tccagcaggg atatcagcga tagatgttgg
     3301 acgagtgtcc attgggaaac gagtttcttc gtagtgtgct ttagtttctt ctacaatttt
     3361 cttgatgtga agtgaacgct ctgttggtcc tgcaaggaag ctttcgtctc catcataagg
     3421 tgtgtagtta gcttgtacaa agcgtgatac acttgctttt tctttccaat ctacgccttt
     3481 gaagccttcc caagctttgt caaaaatatc ttgtgcttca acaactgtct taacaaccat
     3541 attaatgtcc tcttttttct agtaacagtc atctgttaca ttcataagac aagtatacca
     3601 taaagtaacc gatttcaaca agtgcaaaat ccctattttt acactttctt ttctaaaaca
     3661 gtctatattt tatttcaaac tgtattatat ttttgaaaaa aataaagtcc ttttttcttt
     3721 ttttcagaaa aaagggtata ataaaagaaa ataagcagta acactcaatg gaaatcgaaa
     3781 agcaaactag gaagctagcc gcaggctgct caaaacactg ttttgaggtt gcagatagag
     3841 ctgacgtggt ttgaagagat tttcgaagag tataaaaagg tgctaggcat gttgattttt
     3901 cctttgttaa atgatttgtc aagaaaaatc atccatattg acatggatgc cttttttgct
     3961 gcagtggaaa tcagggataa tcctaaactc agaggaaaac ctgtcattat tggaagcgac
     4021 cctcggcaaa caggtggacg gggagtcgtt tctacctgta gttatgaggc aagagctttt
     4081 ggtgtccatt ctgccatgag ttccaaggaa gcttatgaac gttgtcccca ggccgtcttt
     4141 atctcaggaa attatgagaa atacaaagct gtgggactcc agattcgagc tatttttaag
     4201 cgctatacag atttgattga acccatgagc attgacgaag cctatttgga tgtgacagaa
     4261 aataaactcg gtatcaagtc agcggtcaaa attgctcgcc tcattcaaaa agatatctgg
     4321 caagaactcc atctaactgc ttctgccggt atttcctata acaagttctt agctaaaatg
     4381 gcgagtgatt atcaaaaacc tcatggtttg acagtgattc tacctgaaca ggctgaggat
     4441 tttctcaaac aaatgaatat ttccaaattt catggagtag gaaaaaagac agtagaacgt
     4501 cttcatcaaa tgggcgtttt tactggtgct gatttacttg aagttcctga ggtaacccta
     4561 atagaccgtt ttggtagact aggctatgat ctgtatcgaa aggctcgtgg cattcacaac
     4621 tctccagtca aatccaatcg catccgtaaa tcaatcggca aggagaaaac ctacgggaag
     4681 attctccgtg ccgaggaaga tatcaaaaaa gagctgactc ttctatcaga aaaagtcgct
     4741 ctcaatctac atcaacaaga aaaagctgga aaaattgtca ttttgaaaat ccgctacgag
     4801 gacttttcaa ctcttaccaa acgaaaaagt cttgctcaaa aaacacaaga tgctagtcag
     4861 ataagccaaa tagccctgca actctatgaa gaattaagcg agaaagaaag aggtgtccgc
     4921 ctattgggga ttaccatgac tggattttaa agctcaatga aaatcaaaga gcaaactagg
     4981 aagctagccg caggctgctc aaaacactgt tttgaggttg cagataaagc tgacgcggtt
     5041 tgaagagatt ttctaagagt ataaaacctt gaagagttgc cccttcaagg tttttcttat
     5101 acaaataaac ggacaaaact gtaaagtagc aaaacactac caagcacgat acggtattta
     5161 ccaaaaaggg tgaagtcgtg ttttttcaca tagctggtca agaagcgaat agccaccata
     5221 ctgaccgcaa aagctactcc catcgcgacc aagagcaaaa acaattgccc aaagctcaag
     5281 agttctcctg cttttacaaa tttgaaaatc tttaaggcac tagctccaaa cataacggga
     5341 atcccaagat agaaggtaaa ttctgtcaca actgaacgac tggttccatt taacaaacca
     5401 ccgacaatcg ttgcacctga acggctagtc cctggtaaaa gagcaagaac ttggaagagt
     5461 ccgatataga aagcggtcgt ataaggaagc ttgtccaact ctgttacact tggctcgata
     5521 gcacgcgctt tattgcgctt ttccaaatag atgaaggcaa ccccgtagat aatcaacatg
     5581 agagcaactg aaaccatgtt atggaagtgg gtatcaaacc aatcatcaaa tttaaagaca
     5641 ccaagtaaag gcaaagtggc aatcaagacc ttcaaccata gtctccaagt cttacgaact
     5701 tcctgtttgt ccttagtcgg tttaaaagga ttgagcttgt taaaataaat caccataact
     5761 gctaaaatag caccaagctg aatcacgaca ttaaacatgg acataaaggc ttcattttga
     5821 ttttggtatt ggataaactc ctctgctaaa atcaagtgac ctgtactgga aatcggcaac
     5881 cattccgtaa ttccttcaac aatcccgaag aagatagatt ttaaaatttc aataagatac
     5941 atatatttct ccttatatta tatttaacgc agttagctac tgccaaagcc caagtggtat
     6001 acttggaata agccactgtg gattagttca tttcctccaa tcgcttgacg atttccgaaa
     6061 gggtctaacc acagcttttt gtttcaattg gtaatgagtt tgataacgca tagacgtttt
     6121 atctcgtcta aggtaacaag gcaaaaagtt cgtggataac caagtagact tgaaatacta
     6181 tatctggagg tactcccatg ctttatgtgg gcattgatgt cgctaaaaat aaacacgatg
     6241 ttacagcctt gaatgttcga ggaaaactgt tcttaaacca ctcacttttt caaataataa
     6301 agctggtttt gaactcttag atctgtcttt tcgacagctc aaccaagact gtctcatcgc
     6361 tcttaaactt ctttctgacc ccaatcgtga acaatttcaa cacgataatc ggcaagtaga
     6421 cctaaaaata ctggctagac atattcatcg tctcaagaga aaacagtctg attggaaagt
     6481 acaatacact cgttgtcttg atatcatctt tcctgagttg gataaaatcg ttggaaagca
     6541 ttcagaatat acctaccaac tcttgacacg ctaccctaat cctcagaaaa ggattgaggc
     6601 aggatttgat aagctgatag aaattaagcg attgaccgct tctaaaattc aggatatcct
     6661 ctcagtcgca cctcgttcta tcggaacaac atctcctgct cgtgaattcg aaatcatcaa
     6721 acattacaag aggctcattg acaaggcgga aacatgtgtc aatgacttga tggctgagtt
     6781 caactcggtc atcacgacgg ttactgggat tgggaatcgt ttaggggcag tcattttagc
     6841 cgagattcga aatattcatg cctttgatat tcctgctcaa ttacaagctt tcgctggact
     6901 agattcttct atttatcagt caggtcagat tgatttagca ggaagaatgg tcaaacaggg
     6961 ttcccctcat ctgcggtagg tactcataca agctgccaaa gcatgccctc gcttttcacc
     7021 tgcttttaag gcctatctta agactaagtt agaacaagga aaacattaca atgtagccat
     7081 catccacctt gcaaaaaaac ttatccgaac cctgttttat atcctaaaaa agagctgcca
     7141 tttgacgaac aaaaagtgat gtaatttctg aaattaacac aggattacct ttgaaaaaat
     7201 ggactttttc aagagctttt tgccgtgctc taaaatcatc gccaaatcat caaattgaaa
     7261 taagaaatag tttagataaa actattgact tttcttatag tttgtctttt ttctatcttc
     7321 cattatatca tactttttca gtctatggta gctctcttta aaaggcaccg atactgccgc
     7381 cacctccgcc tccagagaag ccaccaccag aacttccact tccagaagat acagagtagg
     7441 tgcttgctgt atttgcgaca ctagcataat ggctcatttg tgctgttgaa tgataaaaca
     7501 tactgtgcca gccataagct acatagagat tgatatctgg attttcaact tgaatctgat
     7561 gaaccttcat caaatgacta accttgtccg catagccaaa taaggttgca tagaccaaga
     7621 gacgattcca aacaacaata ctttccaatt cagccttatc cagtcgtgca atctcacgta
     7681 acatattttc aaaactggtc cagagatagt agacctcagc tcccgcttca tttagaacac
     7741 catcacgatt atctagtcga agcttccaat aatagaaaac agacaaaact aaccctagaa
     7801 aaccaagtat tggcaaaggg aggtaaagat agccatgaac gtctaaactg tacaagaaca
     7861 aaccaaatcc gataaataag ggcaagatag tcaagacacc catacccact tgcaaagcct
     7921 tttccaaacc agttaaagga cgatagtaat ctgggagccc ccagaaggaa actcgttttc
     7981 tcactccttc ttgcatctgg ttcaatacct cttcaaaaga agatttgagt tgaagccctc
     8041 ttgcttgaat ccgtttttca tcagaaactt tggctctacg ataaagacta tcagatacct
     8101 tgtaatccgc aaacaaattg gaaagagttt cttctttttt acctgaaaaa gctagattta
     8161 ggcagtcttt ctcaaagctt gacaaaccat cttcttttac tagcctcaaa ccaactgcat
     8221 ctccttctga aatgatagag acattcccac ggtctatcac atctagcaag gtagcttgaa
     8281 taagttgatc aaaggtgaat tttccagctc ccttgaccaa gggactcact tcctccaagg
     8341 aggtcgagta gactgcttct gataaaacca taggctctaa ttccattggg ggttcataga
     8401 gacgatgatt tttagcatat ttgattgaag gagcggtctt tcttctatag ataaaataga
     8461 aacagatgct caataacaag gagatggaaa ggatcgaagg gaagatccaa gtaagtagtt
     8521 gtttactttg ctctttttct ttaacgatcg aatcctctat cttattaaac tcttctaaac
     8581 gattcccttt caagccctga tccctagcgc tagcaaaatc agttcgcggc cagtaggcat
     8641 gcaattcaac tccacgctta gccggaagat tgtctaaacg aatagtataa tcaaggttac
     8701 tcttttcaac cgttctctct ctaaaaagtt tccctgtatg gaaaaagagt ttctcagccc
     8761 ccttgtctcc ccttacatga aattcaaact tttcaataga ctctgaacta tctgtcatag
     8821 gttgccaatt taattcagcg atatcatcat aaaggaaaag taaatttttt aagttccaga
     8881 cgaggtcaac ttcaactatg tcgccctcct gacctggatt atagactctc acagtataac
     8941 catccgcttc ttctgttact tcgctagtca catctgctag ttctgcaccg ttttttgcgg
     9001 cctgaatctt tggatgaggg tcaatgtcaa acccgctagg catcttacca gcacgtccaa
     9061 gtcccacgat ttggccctta aagtcctcct caaactggta aactatcttc tgtctaaact
     9121 ctgccgtatt gtctgcatga atatacaaat ccccttgata agagtttatc ttgaaatcaa
     9181 tggcaaaaac agagagtgga agaaggcaaa acaagcctaa caccagtaag aaaaaagttt
     9241 ttttcatcaa ctaagccccc tttttatctt tcttatcatt atagcatttt ttcgtaagta
     9301 aaggcttact tatgttgaaa aattacgcat ttttcgataa aataggagac agttattttt
     9361 taatagatca gaataggaga aatcatgaga aaaatatact tatctatttt cacaagtctc
     9421 ttgctgatgc taggacttgt caatgttgct caagccgatg aatatttacg catcggtatg
     9481 gaagcagcat atgctccctt taactggacc caggatgatg atagcaacgg agctgtcaaa
     9541 atcgatggga ccaatcagta tgccaacgga tacgatgttc aaatcgccaa gaaaatcgct
     9601 aaggacttag gtaaagaacc tttggttgtt aaaaccaagt gggaaggtct agtccctgcc
     9661 cttacttctg gtaagattga catgattatc gcaggtatga gtccaactgc agaacgcaaa
     9721 caagaaattg ccttttcgag cagttactat actagcgaac cagttttgct tgtcaaaaaa
     9781 gattctgcct acgcaagtgc taaatctttg gatgacttta acggtgcaaa aatcacttct
     9841 caacaagggg tctaccttta tgacttgatt gcacaaatcc caggtgctaa aaaagaaaca
     9901 gccatgggag acttcgctca aatgcgacaa gctcttgagg ctggtgtcat tgatgcttat
     9961 gtttctgaac gtccagaagc actgactgct gaagctgcga actctaagtt caagatgatt
    10021 caagtagaac ctggtttcaa aactggggaa gaagatacag ctatcgctat cgggcttcgt
    10081 aaaaatgaca atcgtattag ccaaatcaat gccagcattg aaaccatttc aaaagatgac
    10141 caagttgcct tgatggatcg tatgatcaag gaacaacctg ccgaagctac aacaactgaa
    10201 gagactagca gtagtttctt tagccaagtt gctaaaattc tttctgaaaa ctggcaacaa
    10261 ctcttgcgtg gtgctggtat cactctttta atctctatcg tcggaaccat cataggtctc
    10321 attattggac ttgccattgg tgtcttccgt actgctcctc tctctgaaaa caaagtcatt
    10381 tacggcctac aaaaactagt cggctggggt ctcaatgtct acattgaaat tttccgtggt
    10441 acgccaatga ttgttcaatc gatggttatc tactatggaa ctgcccaagc tttcgggatc
    10501 aaccttgacc gtacactggc tgctatcttc atcgtttcaa tcaataccgg tgcctacatg
    10561 actgaaatcg tccgtggtgg tatcctagca gttgacaagg gacaatttga agctgcgact
    10621 gctcttggta tgacccataa ccagaccatg cgtaagattg tcctacctca ggtagtccgt
    10681 aacatcctac ctgcaactgg taatgaattt gtcatcaata tcaaagatac atctgtattg
    10741 aacgttatct ctgttgtcga actttatttc tcaggaaata ccgtggcaac acaaacctat
    10801 caatacttcc agacatttac aatcatcgcc gtgatttact ttgtcctcac cttcaccgta
    10861 acacgtatcc tacgctttat cgagcgcaga atggacatgg atacctacac tacaggtgct
    10921 aaccaaatgc aaacggagga tttgaaataa tgacacaagc aatccttgaa attaaacacc
    10981 tcaaaaaatc ctatggacaa aacgaagtgc taaaagacat ttcactcact gtccacaagg
    11041 gagaggtcat ctctatcatc ggaagctctg gaagcggaaa atcgaccttc ctacgctcca
    11101 ttaacctact tgaaacacca actgatggac aaatccttta tcatggacaa aacgtcctcg
    11161 aaaaaggcta tgacctcacg caataccgtg aaaagttggg gatggttttc caatccttta
    11221 acctctttga aaatctcaat gttcttgaaa acacaatcgt cgctcagaca actgtcctaa
    11281 aacgcgaacg cacagaagct gaaaagattg ccaaagaaaa cctggaaaag gtcggcatgg
    11341 gagaacgcta ctggcaagcc agaccaaaac aactctcagg tggtcaaaaa caacgtgtgg
    11401 ccatcgctcg tgccctctcc atgaatccgg acgctattct ctttgatgaa ccaacatcag
    11461 ctctcgatcc agaaatggtt ggagaagtcc tcaaaatcat gcaggacctg gctcaggaag
    11521 gcttgaccat gattgtcgta acccatgaaa tggaatttgc ccgtgatgtc tctcaccgtg
    11581 ttatctttat ggataagggc gtgatcgctg aagaaggtaa accagaagac ctcttctcca
    11641 atcctaaaga agaccgaaca aaagagttcc ttcaacgcta tctcaaataa aaagaaaagg
    11701 ctgcatcaac cgtgcagtct ttttgctgtc ctcaaaatga aaaggcagat tctctatctc
    11761 tactacttga aggtcaagaa tccgccgtta tccaaagatt aatcttcaaa tttttcataa
    11821 tttttttcat agaaatcaat taggcctagg gctgtttcaa atgaaatatt ttttactttt
    11881 gcacgaccct gcgccagagc aatgatagac atttcacgcg cattcgtttc tttagagata
    11941 cggtagcctg tgattttctt atcacgaacc cagccaacaa ctgattctac tttttcaaag
    12001 tttgacttag ccatgttttt ctcccatttt cttctttata atatttaatt gtatacgttt
    12061 ttactacttt tgtcaataaa aaaaacatat attcaacgaa aataattagt tcagaatttt
    12121 cttacttcct ttttaaatcc gataatatat aggttttgct agcctctaca ccataaatat
    12181 ttgctaataa aaatactgta ttattaccct cttaaggtgc gaaattattc aagttcttaa
    12241 aaaatgcttc tctatttccg taagatagct tatttcttcg atttaagaac tgaagatgat
    12301 agttctaacc tttagaaatc caagccttca ctagctcaaa aactcctatc tttcttcctc
    12361 aataaatcat ctgagagata ggtattcctt atgtccttca aattcatcac tcctttggat
    12421 attgaggtgc tagcctagaa gcagacaccc gattatctaa accatcctta atagagatga
    12481 caagacagat aagctcagtt aattacttat atatcttttt aatatggtat atttgtcaac
    12541 aaaaagaaat caaatcatac cttatactca atgaaaatca aagagcaaac taggaagcta
    12601 gccgcaagtt gctcaaaaca ctgttttgag gttgcagata gagctaacgt ggtttgaaga
    12661 gattttcgaa gagtattaaa aacagtgtga ctatgcttgt caatagatag gaaatcaaaa
    12721 tgaaggatgg aaatctgagc caaacatcat aagtgctata atgaacagaa gtaagaattg
    12781 cacgataagt tttctaaaac cataggaatc gtcccctttc ttcatcttca ttatagcaca
    12841 tatacatcag ttgtacaaat aatatgatat ttttttatta gtcctcagac aagcatatta
    12901 taaagcgttt cattaccatt taagttaata taagctggat caaaaccttc cattctacga
    12961 atcaaacctg cataatcatg cttatctgct aaagcgatcc caattaatac tgggcctgtt
    13021 cccttgctag ctcgtttgat atactcaaaa cgtgtgatat catcatttgg ccccaggata
    13081 tcatttacaa actcacgcaa agctcctgga cgttgtggga aattgaccac aaagtaatgt
    13141 ttgataccat cataaatcaa ggcacgctct tccatttctg gcatacggtt gatatcatta
    13201 tttcctccag aaatgataca acaaatggtt ttccccttaa tatattcagc taaaacctct
    13261 aaagaggcga tactagccgc tccagcaggt tctgcgacta tcccttgctt agagtaaagg
    13321 tcaatcaagg tttcagaaat caatccctca tcgacaccta ccaaagtttt aatatgttga
    13381 cgagttgctt cataggtcaa ctgacctacc ttttgcacag caatcccatc agcaaattta
    13441 tcaatttcct tgagttttac tggacctcca gcctcaaagg cagctttcat ggaacgcgct
    13501 ccattcgcct ctactccgat aacctcaatc tctggacttg tttccttgat ataggtagaa
    13561 accccggcaa tgagaccgcc accaccaaca ggaaccaaga cagcatcaaa atcaatcgat
    13621 tcttttcgag cttcttctaa aatctcataa gcaactgttc cttgacctgc ttgaacatga
    13681 gcatcatcaa aaggatcaat aaaggtacga ttttcagaga ctgtaaattc ttgagctgct
    13741 ttggctgagg catcaaaggt atctccaact agtttaatag ttacaaaatc cccaccaaaa
    13801 aagcgaacct gaccaatctt ttgttgtggc gtagtaatgg gcataaagat agtagcagga
    13861 attttcattt cattacaagt ataggctact ccctgcgcat gatttcccgc agaagcgcag
    13921 actaccccac gttcacgttc ttccttgctg agctgggaaa tggcataata ggcaccacga
    13981 attttaaagg agcgaacacg ctgggcattt tcttttttca aataaatctt agcaccatac
    14041 ttctccgata aataatgatc gtaatccagt ggagtattca caaccacacc gttcaagacc
    14101 ttgtgagcct tgattatatc ttttgaactt aacatataaa acctcttttt ctataaaaaa
    14161 cagtcactaa tgactgtttt ttagttattc atctccgaaa acttcagtaa cactttcatg
    14221 gtatttatga gccatacgaa tcgaaaactc tttaggaagt tcataacgat ttgtggaaat
    14281 ccaatcatat aaccattcta ccaaactttc ttcactatca ttacgatgga agataaaata
    14341 gtttaaaatt tctttatatt ctacatcatt caaatccaac gtgtctacaa attgactacg
    14401 aggaacaaaa ttagaatcta attttcttag ttgatctgtc aattctccca attgtaaatc
    14461 caactgaaaa aatagttttt gcagttgcct atcagtttca tcacatcctg tcttgataga
    14521 aaacaaattg gtaatattca tatgatttca acccctaaat aagtacatct aatatcccac
    14581 gaatagctga agctaaagtt ttcgcagtcc agtcatttaa acccgattct ttcaatccag
    14641 atgcaataat ttgctctatt tgatataaac cgccatctat cgtctcattt attctgcgaa
    14701 gaggaccttc aatataggat aaagcttctc cgaatctaac agctgattta ggtcctaatg
    14761 atttaccaac tatatttgtt aatgtttttt atttctcaaa atccatttcg ctatataacg
    14821 agcagattta gtcgcaccag ctctctcaaa cggaaaatga atttcaagac cttcttctct
    14881 agctatttgt gccaatttga agaattgttc aaaggtcata tgcaacctac catcttcaaa
    14941 attagcatca tcataaatgt taattacagt attttcatca tacgaccaat ctgctttatt
    15001 ttggtctgct agcactatta ccgacggtgt aattacatta tacaactaga accaataata
    15061 acgatgcaat ttttctcata atctttttca taaaatcatc tccagcgcta tatatttcta
    15121 attagttata gattttgaat gcatcatcgt cgtttttacc aacgaatggc attgctttac
    15181 gcaattctgc accaactttt tcaatttcaa ggttagctgc ttgttcacgg taagcagtca
    15241 attttggacg tccagcttta tagtcattta caaagtcatt tgcaaattta ccattttgga
    15301 tgtctgccaa gacagccttc atattttctt taacttgttc agtgattaca cgtggacctg
    15361 atacatagtc accgtattca gcagtgtttg aaatagattg acgcattttc ttgaatccac
    15421 cttcgtagat caagtcaacg atcaatttca tttcgtgaag aacttcaaag taagccaatt
    15481 ctggagcgta acctgcttct gtcaagactt cgaaacctgc ttcgataagg gcagtcaaac
    15541 caccacaaag tacagcttgt tcaccaaaca aatcttcttc agtttcttct ttgtaagttg
    15601 tttcaagaag acctacacga gccgctccaa cacctttaca ccagtccata gcaatgtttt
    15661 tagcatttcc tgttgcatct tggtatactg cataaagagc tggaacacca aatccttctt
    15721 cgtaagtacg acgtaccaag tgtcctggtc ctttaggagc acacatgaag acatctacat
    15781 ccgcaggaac tttgataaat tcaaagtgga tgttgaaacc atgggcaaat ccaactgcgt
    15841 ttccagcttc caagtttgga gcgatttctg cttcgtacaa ttcttgttga atttcgtctg
    15901 gcgccaagat catgataaca tcagccaact tagtagcttc tgttactgtg taagtatcaa
    15961 atccatcttc ttttgcttta tcaaaagatt tacctggacg tacaccgata ataacgtcac
    16021 gacctgaatc acgcaagttt tgagcatgcg catgcccttg tgaaccataa ccgataacgg
    16081 cgattttttt accgtcaagt gctgctactt taacatcttt ttcatattcc atttgaactg
    16141 tcatagcttt tctctctttt ctattattta ttgcctttta agctggttta acaaatttaa
    16201 gttggatttt taatcgcggg taaatccagt tgcacccgtt cgagcaatat tgcgaatacc
    16261 gtatgggcga atgactcgca atagggcttc gctcttttct gcatttcccg tcatctgaat
    16321 ggtaatcgag cttggcgcta cgtctaccac tgttgcacgg aaaggttgaa taatcgctaa
    16381 aatctcagct ctcttctcag ctggcgctga catcttaacc aaaatcacct cgcgctccaa
    16441 atgaggcttg tctgtaatat ctcgaatgcg aatcacatca atctgacgat tgagctgttt
    16501 gatgatttgc tccacttcat catgagaagc aacatcaata ataatagtga tacgcgatac
    16561 attcggatct tctgttgctc caacagagat gctttcaata ttaacctgac gacgagatag
    16621 gacacctgta aagcgattga ggactcctga acgattttgt agttttgctg ttaacattct
    16681 acgcatggaa cttcaccccc aacatctcat gattactctt accagccggt accattggta
    16741 acacctgttc cttacgagaa atatctacct caattagcat aggaacatcc tcagtgatga
    16801 cttcaaggtc ttgagccaag gtctcaggat tgtcaaactt atagttttta ataccataag
    16861 cctgcgccat caattggaaa tcaggaaggg tatcaaagac cgactctgat gttctgcctt
    16921 catagaagga ttcctgccac tggcgaacca ttccaagtga atgattgttc agcataacca
    16981 ccttgattgg caccttgtaa atattcaaaa tagccaactc ctggttggtc atttggaaac
    17041 caccatcccc aacaaacaag actacttcct tatctgggtt agcaatttta gcaccgattg
    17101 ctgctggaat tccaaagccc attgttccca aaccacctga agtcactaac tgacgctcat
    17161 tttggtaggg ataatactga gctgtccaca tttggtgttg accaacgtct gttaccacaa
    17221 tggcatctcc attcgtcaat tcaccaattc gttcaataac tgcttgcggt tgaaccacac
    17281 gctctttctt gtcataagaa cgaacacgat tcttgtcttt agtgactttc tcaatccact
    17341 tttcagtatt gttgtgaact gttggttctg ctagcaacat ttgcaaggcc ttcttagcat
    17401 ctccaactac aggaatgtct gcactgataa tcttgccaat ctcagctggg tcaatatcaa
    17461 tgtgggcaac cttagcattc ttagcgaaag tcttaggatt ccccgtcaaa cggtcatcga
    17521 aacgagaacc aatactaatc ataaagtccg cttccgtcat ggcaatattt gctgcgaatg
    17581 acccgtgcat gcctcccatt ccaagaaaga gtgggtgact cgttgcaatc gttccttgtc
    17641 ccaaaagact ggttaccact ggaatttgat agcgttctgc aaattcattt agttccgtag
    17701 cagcctcagc ataactaatt ccaccaccag ctaacaagac tggcttttta gccttggaca
    17761 attgcttcaa gattttcttg atttgcatat cattcggctc aagagtcggc tgataacttg
    17821 gtaaattcac ttctggtgaa taaatgaagt ctgtttctaa agcagatatg tcttttggta
    17881 ggtcaattac aactggccct ggacggcctg tagttgcgat atggacagct tccgtgatga
    17941 tacgcggaat atcagctgtc tcacgaactt ggtaattgta cttagtgatt ggcatggtaa
    18001 ttcccacgat gtctgcctcc tgaaaggcat ccttcccaat ccctgctcgc gccacctgac
    18061 ctgtaaagac caaaagggga acgctatcgc tcatggcatc cgcaatccct gtaatggcat
    18121 ttgttgctcc tggtccacta gtgacgacgg caacacccaa ctttccagtt gatttggcat
    18181 aaccttcagc ttcatgcaaa caaccttgct catggcgccc tagaatgtgg cgaatgcctt
    18241 taaaattata tatcgcatca taaaaaggca aaaccgcacc accaggataa ccaaagatgg
    18301 tatcaactcc taaatcacga agtgtttcca aaactaggtc cgaccccgtc ttaggagatt
    18361 ctaaactgat tttctccatt attccccttt ctttcctctt aaaaataact tgttactatc
    18421 at
//
LOCUS       DAVKBC010000037        18065 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVKBC010000037 DAVKBC010000000
VERSION     DAVKBC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18065
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.037"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            327..1373
                     /gene="pheS"
                     /locus_tag="VWX64_001542"
     CDS             327..1373
                     /gene="pheS"
                     /locus_tag="VWX64_001542"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU9190989.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKIISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1373..1882
                     /locus_tag="VWX64_001543"
     CDS             1373..1882
                     /locus_tag="VWX64_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190990.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMQEEEIAAFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1959..4364
                     /locus_tag="VWX64_001544"
     CDS             1959..4364
                     /locus_tag="VWX64_001544"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU9190991.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVELPAAGLSK
                     IVVGEVLSCEAVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4432..5433)
                     /locus_tag="VWX64_001545"
     CDS             complement(4432..5433)
                     /locus_tag="VWX64_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9190992.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5581..5984
                     /locus_tag="VWX64_001546"
                     /pseudo
     CDS             5581..5984
                     /locus_tag="VWX64_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6110..6376
                     /locus_tag="VWX64_001547"
     CDS             6110..6376
                     /locus_tag="VWX64_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9190993.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            6637..8886
                     /gene="metE"
                     /locus_tag="VWX64_001548"
     CDS             6637..8886
                     /gene="metE"
                     /locus_tag="VWX64_001548"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU9190994.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8950..9816
                     /gene="metF"
                     /locus_tag="VWX64_001549"
     CDS             8950..9816
                     /gene="metF"
                     /locus_tag="VWX64_001549"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU9190995.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10501..12714
                     /gene="pnp"
                     /locus_tag="VWX64_001550"
     CDS             10501..12714
                     /gene="pnp"
                     /locus_tag="VWX64_001550"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU9190996.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12730..13347
                     /gene="cysE"
                     /locus_tag="VWX64_001551"
     CDS             12730..13347
                     /gene="cysE"
                     /locus_tag="VWX64_001551"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU9190997.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13359..14243
                     /locus_tag="VWX64_001552"
     CDS             13359..14243
                     /locus_tag="VWX64_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9190998.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDKDVEVTILVHPGHRRQGIARALFTSFERGTASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14325..15668
                     /locus_tag="VWX64_001553"
     CDS             14325..15668
                     /locus_tag="VWX64_001553"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU9190999.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15661..16047
                     /locus_tag="VWX64_001554"
     CDS             15661..16047
                     /locus_tag="VWX64_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU9191000.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16051..16935
                     /locus_tag="VWX64_001555"
     CDS             16051..16935
                     /locus_tag="VWX64_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU9191001.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17072..17506
                     /locus_tag="VWX64_001556"
                     /pseudo
     CDS             17072..17506
                     /locus_tag="VWX64_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17814..17984
                     /locus_tag="VWX64_001557"
                     /pseudo
     CDS             17814..17984
                     /locus_tag="VWX64_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5442 a         3478 c         4090 g         5055 t
ORIGIN      
        1 cttatttcaa tccgctataa agttagataa gaataagcta acaagcagaa gtaagatagg
       61 tcttgcaaga atggtaaaaa tctgataaac taagtagtaa ttgaatagga atctgaaaga
      121 ctagtagccc aagggaagta tatcagggag gagagccgtg actgcaagct ctctatatga
      181 aagctgggtg aattcacttg cgcatggatt tagaaatgaa ggtctgactt gtcagatgaa
      241 aacggatggt accgcgtgtc aacgctccga gtggagtttt tggcatgtgg ttttcttttt
      301 atctacgaga gactgatgga ggaaatatgt caactattga agaacaatta aaagcgcttc
      361 gcgaagaaac gctgactagc ttgaagcaga ttactgctgg aaatgaaaaa gagatgcaag
      421 atttgcgtgt ctctgtcctt ggtaaaaagg gttcgcttac tgaaatcctc aaagggatga
      481 aagatgtttc tgctgagatg cgtccaatca tcgggaaaca cgtcaatgaa gctcgtgatg
      541 tcttgacagc tgcttttgaa gaaacagcta agctcttgga agaaaagaaa gtcgcggctc
      601 aactggctag cgagagtatc gatgtgacgc ttccaggtcg tccagttgcg actggtcacc
      661 gtcacgtttt gacacaaacc agtgaagaaa tcgaagatat cttcatcggt atgggttatc
      721 aagtcgtgga tggttttgaa gtggagcaag actactataa ctttgaacgt atgaaccttc
      781 caaaagacca cccagctcgt gatatgcagg atactttcta tatcactgaa gaaatcttgc
      841 tccgtaccca cacgtctcca gttcaggcac gtgctatgga tgcccatgat ttttctaaag
      901 gtcctttgaa gataatctcg ccagggcgtg tcttccgtcg cgatacggac gatgcgaccc
      961 acagtcacca attccaccaa atcgaaggct tggtagttgg gaaaaatatc tctatggctg
     1021 atcttcaagg aacgcttcag ttgattgtcc aaaaaatgtt tggtgaagag cgtcaaattc
     1081 gtttgcgtcc atcttacttc ccattcacag agccatctgt tgaggtggat gtttcttgct
     1141 tcaaatgtgg tggagaaggc tgtaacgtat gtaagaaaac aggttggatc gaaattatgg
     1201 gggccggtat ggttcaccca cgtgtccttg aaatgagtgg tatcgatgcg actgtatact
     1261 ctggctttgc ctttggtctt ggacaagagc gtgtagctat gctccgttat ggaatcaacg
     1321 atatccgtgg attctaccaa ggagatgtcc gcttctcaga acagtttaaa taatgattag
     1381 aaaagtagaa atggcagatg ttgaggtgtt ggctaaaatt gccaaacaaa cctttcgtga
     1441 aacctttgcg tatgataata cggaagagca gttacaggaa tactttgaag aggcttatag
     1501 tctgaaaact ttgtcaactg agttgggaaa tcctgactct gaaacctatt tcattatgca
     1561 ggaggaggag atagctgctt ttctcaaagt caactgggga agtgctcaaa ctgagagaga
     1621 attagaggac gcttttgaaa ttcaacgcct ctatgtgcta caaaaattcc aaggatttgg
     1681 actaggtaag caactgtttg aatttgctct tgaacttgct acaaaaaata gtttttcttg
     1741 ggcttggcta ggtgtttggg agcataatac aaaagctcaa gcgttttata accgatatgg
     1801 ttttgaaaaa tttagccaac atcattttat ggttggtcaa aaagtagata cggattggtt
     1861 actgagaaag aaattaaggt aagaagagga ttcttctatt gaaatgatag gaaaggaaaa
     1921 gaactagagt gacaactgtc attctggaga actaaattat gcttgtatct tataaatggt
     1981 taaaagaatt ggtggacatt gatgtgccat cacaagagtt ggctgaaaaa atgtcaacta
     2041 cagggatcga ggtagagggt gtcgaattac cagctgctgg tctctcaaaa attgtcgtcg
     2101 gtgaggtctt gtcttgcgaa gctgtgccag agactcacct ccatgtttgt cagattaacg
     2161 ttggcgaaga agaagagcgt cagatcgttt gtggtgcccc aaatgtgcgt gctgggatca
     2221 aggtcatggt ggctcttcca ggagctcgta tcgctgataa ctacaaaatc aaaaaaggaa
     2281 aaatccgtgg tttggagtca cttggaatga tctgttcact tggtgaattg ggaatttctg
     2341 actcagttgt gcctaaggaa ttcgcagatg gcatccaaat cttgcctgaa gatgccgtgc
     2401 caggtgagga agtcttttct tacctagact tggatgatga aatcatcgaa ctttccatca
     2461 caccaaaccg tgcagatgcc ctttctatgt gtggagtggc tcacgaagtg gcagccatct
     2521 atgacaaggc agtcaacttt aaaaaattta ctctaacaga aactaatgaa gctgcggcag
     2581 atgccctttc tgtcagcatt gagacagaca aggcgcctta ctatgcagct cgtatcttgg
     2641 acaatgtgac tatcgcacca agtccacaat ggttgcaaaa ccttctcatg aacgaaggca
     2701 tccgtcccat caataacgtt gtagacgtga caaactacat cctgctctac tttggtcaac
     2761 ctatgcatgc ttttgacttg gacacatttg aagggactga catccgtgtg cgtgaagcgc
     2821 gtgatggtga aaaattagtg accctggacg gtgaagaacg agacttggct gagacagacc
     2881 tcgtgattac agttgctgac aaaccagtag cccttgccgg tgttatgggt ggtcaggcta
     2941 cagaaatttc tgaaaaatct agtcgtgtta tccttgaagc tgctgttttt aatggcaaat
     3001 ctatccgtaa gacaagtggt cgcctgaacc ttcgttctga gtcatcttct cgctttgaaa
     3061 aaggaattaa tgtggcaaca gttaatgaag cccttgatgc ggcagctagc atgattgcag
     3121 agcttgcagg cgcgacggtg cgtaagggta tcgtttcagc gggtgagctt gatacctctg
     3181 atgtggaagt ttcttcaacc cttgctgatg ttaaccgtgt cctcggaact gagctgtctt
     3241 atgctgatgt agaagacgtc ttccgtcgtc ttggctttgg tctttctgga aatgcagaca
     3301 gctttacagt cagcgtacca cgtcgtcgtt gggatatcac aatcgaagct gatctctttg
     3361 aagaaatcgc tcgtatctat ggatatgacc gcttgccaac cagccttcca aaagacgatg
     3421 gtacagctgg tgaattgact gtgatacaaa aactccgccg tcaagttcgt accattgctg
     3481 aaggagcagg tttgacagaa atcatcacct atgctctgac aactcctgaa aaagcagttg
     3541 agttcacagc tcaaccaagt aaccttactg aactcatgtg gccaatgact gtggatcgtt
     3601 cagtcctccg tcaaaatatg atttcaggga tccttgatac cgttgcctac aacgtggctc
     3661 gtaagaataa aaacttggcc ctttatgaga ttggaaaagt ctttgaacaa acaggtaatc
     3721 caaaagaaga acttccaaat gagatcaaca gctttgcctt tgccttgaca ggcttggttg
     3781 ctgaaaaaga tttccaaaca gcagcagttc cagttgattt cttctatgct aagggaatcc
     3841 ttgaagccct atttactcgt ttgggactcc aagtaaccta tacagcaaca tctgaaatcg
     3901 ctagccttca tccaggtcgt acagccgtga tttcactcgg tgaccaagtt cttggtttcc
     3961 ttggccaagt gcatccagtc actgccaagg cttacgatat tccagaaacg tatgtagctg
     4021 agcttaacct ttcagccatc gaaggggcgc tccaacctgc tgttccattt gtggaaatca
     4081 ccaaattccc agcagtcagc cgtgacgttg cccttctcct caaggcagaa gtgactcacc
     4141 aagaagttgt agatgctatc caagctgccg gcgtgaaacg tttgacagat atcaaactct
     4201 ttgacgtctt ctcaggtgaa aaactgggac ttggtatgaa gtcaatggct tatagcttga
     4261 ccttccaaaa tccagaagac agcttaacgg acgaagaagt cgcacgctac atggaaaaaa
     4321 tccaagcgtc tctcgaagaa aaagtcaatg cagaagtgcg ttaaacgata gtaggataca
     4381 aattccccct ctagtttatg aacactagag gggtgatttt atataaaata attaaaatgt
     4441 gatttctgta aaaatacatc tatgatcaga gttttgaaaa cttacaatgt ctaaatcttt
     4501 aacatagtag tggtttttag gcaataaaat atgatctatt gttgcattaa aaagttttgg
     4561 actttggcta ttccaagttc ctctttcaaa aggtggcagt acatttaatg cgtccctatg
     4621 agagcttatt tttgcaagtg ctccatgacg catagttgca ttaaaatcac ctgcaataat
     4681 agcctttgga tattttgaag ccaattgatt atgaatgatg tttaagtctt gcttccagat
     4741 ttccattaaa cctggcagag gaggagcagt atgcaaggca atgatatctg gtatattttg
     4801 ttttctcgaa tgtaatacaa ttgtcccgaa ccgtgttgta tgaaaagttt tagcttctgt
     4861 atagaaacca taacttttct tgacaatcac agtcacagga gctattccac tattggtagg
     4921 tggagaagtg aaaatatcat agttggccat agaaagtcca acttgatgaa acaatagttt
     4981 gattctctgg ttttcttgct cacctctgat attggtagct agttcaggga atatagccat
     5041 atcggcgtca aaatggctaa aaattcgctc aatatgttgt gcttctattt gattagcgac
     5101 gttccaagtt actaatttta aggttttagt cttatttgat gcagaagaaa gggttttatc
     5161 tgttccgaat aatagtaata tgagcgatag taagagcaaa atgccagagt aaaaccgtat
     5221 ttgtttattt ttcttgtaaa aagataggga aaaaaatacg aaacttaaaa tagaagccat
     5281 agttgcagta gctaagggga aggcataaat ctgtgccaag ataggttggg tagatagcca
     5341 aatattaaga ttagaagatg gaaaaaaaga ataagctatg atagggataa caaagagaat
     5401 gaccgaaagg gcagagagaa atgttttaat cattgtgtga gtacctcaat ttgcaatggt
     5461 tgctcggagc taatgtgact ttacttgatt gatattcttt ttcttgtctt ccttatagat
     5521 taagtacaac ccaagtaaaa aaagtccaat ttaagattga aatgattaaa aggcacagaa
     5581 atgcaagaca attatactac aaaaggcaaa catttgacaa tcgatagccg tcgcttaatc
     5641 gaacgatgga aaaaagaagg aaaatcaaat agagaaattg cctctctact tggaaaagct
     5701 cctcaaacta tccacactga aataaagcgt gggacagtcc gacaatgtct tggaaaaggg
     5761 cgcttcaaag agatttattc tgccgactac gctcaacagt cttaagaaac taaaggaaaa
     5821 gattctccac tatacataac caaaaatttt cgcctgaaat gatggttatg gctaaagggg
     5881 ttaacgtggg aatttcaacc atttactatt ggattcatcg tggaaaattg gggttaagca
     5941 agcaggatct gctttatcct agaaaaggaa aatcgcttaa gaaataggct agcaccaact
     6001 ttaaacccac tggtcaatct atcgaatcat aattcgctca tttttttaaa aatacataga
     6061 cgtaaaaaaa agagggttaa gtgatgaaga atagtgctat tgggagtaat tggaaggatg
     6121 tccatctgag ctctttagca aggaggaaat ccttgaaagt gatatgcgag tggctatcat
     6181 gagcgagttg attgaggcta ggtatgaaca aggaatcagt cagaaaaagc tggaagaagt
     6241 cagtggaata agccagcctg tcatagctag gatggagaca ggaaagacta gtcctcagtt
     6301 ggatacagtc ttaaaagtcc tagccagttt aggaaagaca ctagcaatcg tcccacttga
     6361 acagggaaaa agttgactag aatcagttat agtcttttct aataacaggt catagtcact
     6421 tataagaatt actaataaca tgttttagta ttctaattgg aatatagctg taaagtaaga
     6481 attacaaagg atttgagacg tttgcttcaa gtctttttct tttgtccgaa acagatatat
     6541 agtttcaaac tatatcaaac cctaattttt tacaattata cagacgcttt cttttctgtt
     6601 aagatagttt caacaacaaa ttttggagga cacatcatgt caactacaat catcggtttc
     6661 cctcgtttgg gcgaattccg tgaattaaaa tttacaactg aaaaatactt tagaaaagaa
     6721 atctcagaag aagaactttt agcagcagca aaagacttgc gtgctaaaca ctggaacatt
     6781 gtcaaagaaa aaggcatcac tgaaatccca tcaaatgact tttctcacta tgataacttc
     6841 ctagatgcgg ctttcctttt caacgtagtg cctgcctcag ttcaaaactt ggacttgtct
     6901 gaccttgagc gctacttcgc tttgggacgt ggttaccagg gagaaaaagg ggacgttcgc
     6961 gcccttccaa tgaagaaatg gttcaacact aactaccact acatcgttcc taaatttgaa
     7021 aaagacactc aagtaaaatt ggctggtcac aagattttcg atgagttcca agaagccaaa
     7081 gaacttggat tgaacactcg tcctgttctt gtaggtccct tcactttcct tcaattgtca
     7141 gactttgaag aaggcgtgaa agcagacgac ttcgtagata gcttagtggc tgcttaccaa
     7201 gaagtttttg ctaaattggc tgaacttggt gcgactcgca tccaattgga tgaagcggct
     7261 cttgtaaaag acttgacagc tgaagaaaaa gctctcttct tgaaccttta caacaaactc
     7321 ttggctgaca aaaaaggtct tgaagtcttg cttcaaactt atttcggtga tgttcgtgac
     7381 gtatacgctg accttgtaaa cttaccagta gatgctatcg gtcttgactt tgttgaaggt
     7441 aagaaaactc ttgaactcgt taaaggtggc ttcccagctg acaagactct ctatgtaggt
     7501 attgtcaatg gtaaaaacat ctggcgcaac aactacgaaa agagcttggc tgttcttgag
     7561 caaatcccag ctgaaaacat cgttttgaca agctcttgct cacttcttca tgtgccattt
     7621 acaactgcta atgaagaatt tgaaccagca ctcttgaacc actttgcctt tgcagttgaa
     7681 aaattggatg aaatccgtga cttggatgct atccgcaatg gtcaaggttc agaagctctt
     7741 gcagccaaca aagaactctt tgcgactgag cgtgttggtg aaaatgctga acttcgtgcg
     7801 cgtatcgctg gcttgacaga cgcagactac actcgtttgc cagcctttgc agaacgtgaa
     7861 gctatccaag aagaagcttt caaacttcca gctcttccaa caacaacgat tggttcattc
     7921 cctcaaacaa aagaagttcg tgccaaacgt ttggcttacc gtaaaggtga attgtctcaa
     7981 aaagagtacg atgctttcct tgctgaaacg attgacgaat ggatcaagtg gcaagaagat
     8041 attgactttg atgtccttgt tcacggtgaa tttgagcgta atgacatggt tgagtacttc
     8101 ggtcaaaact tgtcaggata cctcttctct aaaaatggat gggtacaatc atacggtatg
     8161 cgtggggtaa aaccaccaat catctggggt gatgtcactc gtcttaaccc tatcactgtt
     8221 aaatggtcta gctatgcaca aagtcgtaca aacaaacctg ttaaaggtat gttgactgga
     8281 cctgttacca tccttaactg gtcattccca cgtgaagaca tctctatcaa ggattcaact
     8341 ctccaaatcg cccttgctat caaggatgaa gtacttgacc ttgaagctgc tggtgtgaaa
     8401 atcatccaaa tcgacgaggc tgctcttcgt gaaaaattgc cactccgccg tagcgactgg
     8461 tacgaagact accttgactg ggctattcct gccttccgct tggtacactc aacagtagcg
     8521 ccagacacac aaatccacac tcacatgtgt tactcagaat ttacagatat catcccagct
     8581 atcgataaca tggatgcaga cgttatttcc tttgaagcta gccgttcaaa ccttgaaatc
     8641 ttggacgaac tcaaagcgaa aaacttccaa acagaagtgg gacctggggt ttacgatatc
     8701 cactcacctc gtgtaccaaa tgaaggcgaa atcgacaaca caatcgaagc catccttgct
     8761 aaagtgccaa gcaagaaagt ttggatcaac cctgactgtg gtttgaaaac acgtggtatc
     8821 ccagaaacaa aagaaagctt gatccgcctt gttgaagcag ctaaagctgc gcgtgagaaa
     8881 ttgtaagatt ggatttctct ccatacagtg gttgttcaaa aagaaatcaa ctagaaaagg
     8941 ttattacata tgtcacgcca aacaccgtca ctctcatttg aagtgttccc tccaaaccca
     9001 gccgtgggta atgataacat tatttcagcc ttgcaggata tgcaggagtt ggctccccat
     9061 tttatcagtg taactgccag caataataaa tttaatatca aggaaacgac ggttcgtttg
     9121 gctgacttta tccaaaatga tttggcgatt ccgaccattg cccacttgcc agctatttat
     9181 ctaactaagg acaaggttgc tgaaactatt gctgacttgg acaaagttgg ggtgcagaaa
     9241 atcttggctc ttcgtgggga tattattcca gacgtggaac cacaaaagga tttccgctat
     9301 gcaaccgact tgattgagtt tatcaaggaa caaacccctc actttgatat tattggagct
     9361 tgctatccag aagggcatcc agattcgcca aatcagattt cagatattca aaatcttaag
     9421 aagaaagtgg atgcaggctg ttcgagcctc gtaactcagc tcttctttga caatgagcgc
     9481 ttctatgatt ttcaggacaa gtgtattttg gctgggattg atgttcccat tcatgcagga
     9541 attatgccaa ttctgaatcg aaatcaggct ctccgactct tgaagacttg tgagaatatc
     9601 catcttccac gcaaatttaa agccatctta gacaagtatg agcatgaccc tgagtcgctc
     9661 agagcagcag gacttgccta tgcagtggac caaatcgtgg acttggtaac tcaggatgtt
     9721 gccggtgtgc atctctatac gatgaataat gctgatacag caaaatacat ccatcaagca
     9781 acccatgcct tgtttaatca ccagtctcta ggataataaa agcaaaccat tcttctcagg
     9841 tgaggggaat ggttcctttt taatggcaaa gacctcactt tttaagaaaa atatgataaa
     9901 atagattctg tacgtacttg atacaaagat gaaggtatta aataatacaa tgcatttaaa
     9961 ctgtaagatt taacgacacg agtgagtcaa atcgatgtta tttgacgaaa gagttagtaa
    10021 agcatttagc taatcgcccg atagcaatta gcgtgaaagg tttagatact ttaatattaa
    10081 acctttctaa tgatgtatct tgaaaactga acttgcctac aactctgtgg aaaaagataa
    10141 atctccctag gagcagtcgc tccgtcgttc gatttcctat cttcctttga gttgcttgac
    10201 ggcttggtat cttgatgact tgaattttgg tctcatttct taggaaaaaa gataagcttc
    10261 ctagcactcg tcgagtgcga cgtcaccttc ctatttttct acagaaatgt tcggcaagcc
    10321 gaaccgtcca aaatatcttg tgtaattgaa cacggccgaa aagctgtgta aaaaagataa
    10381 actgtcttgt cttcatcgaa gacttcgtca gtttcctatt tttactttgc ttttgacgtc
    10441 cttggtatct tgatctttgt aggcaaggcg tataatttca tcaatccaaa ggggattaaa
    10501 atggcaaaac aagtgtttca aacgactttt gcgggtcgtg agttaattgt agagactggt
    10561 caggttgcta agcaagcaaa tggatctgtt gtcgtacgtt acggtgagtc aactgtcttg
    10621 actgctgccg ttatgtctaa gaaaatggca actggggatt tcttcccact ccaagtcaac
    10681 tacgaagaaa aaatgtatgc ggctgggaag tttcctggtg gctttatgaa acgtgaagga
    10741 cgtccttcaa cagatgcgac cttgacagcg cgtttgattg accgtccgat tcgtcctatg
    10801 tttgcggaag gtttccgtaa tgaagtccaa gtcatcaata cagtgctttc ttatgatgaa
    10861 aatgcatctg caccaatggc tgctatgttt ggttcatctt tggcactgtc tatttcagat
    10921 attccatttg acggaccaat tgctggggta caagtgggat atgtagatgg ccaaatcatc
    10981 atcaacccaa gtcaagaaca agcagagcaa tctcttcttg aattgacagt agctggaacc
    11041 aagcacgcta tcaacatggt agagtctggt gccaaagaat tgtcagaaga aatcatgttg
    11101 gaagcgcttc ttaaagggca cgaagctgtc aaagaattga ttgccttcca agaagaaatc
    11161 gttgctgctg tcggtaaaga aaaagcagaa gtggaattgc ttcacgtgga tgctgaattg
    11221 caagctgaaa tcattgcagc ctacaacagt gacctccaaa aggcagttca agtagaagag
    11281 aaattggccc gtgaagctgc aactcaagca gtgaaagacc aagtgactgc cgtttacgaa
    11341 gaaaaatatg cggaccacga agaatttgac cgtattatgc gtgatgtggc tgaaatcttg
    11401 gaacaaatgg aacacgcaga agtgcgacgt ttaattacag aagacaaggt gcgtcctgat
    11461 ggtcgtaagg tcgatgaaat ccgtcctttg gatgcggttg ttgacttcct tcctcgtgta
    11521 catggttcag gtctctttac tcgtgggcaa actcaagctc tttcagtctt gaccttggct
    11581 ccgatgggag aaactcaaat cattgatggt ttggatccag agtacaagaa acgctttatg
    11641 caccactata acttccctca atattctgta ggggaaacag gtcgttacgg tgcgccaggt
    11701 cgtcgtgaaa tcggtcacgg tgcccttggt gagcgtgctc ttgctcaagt cttgccaagc
    11761 ttggaagaat tcccatacgc tatccgtcta gtagcagaag ttttggaatc aaacggttct
    11821 tcatctcaag cttctatctg tgcgggaact cttgccctta tggctggtgg tgtgccaatc
    11881 aaggcgccag tagctggtat tgctatggga cttatctcag atggaaataa ctacacagta
    11941 ttgacagata tccaaggttt ggaagatcac tttggagata tggacttcaa ggttgcaggt
    12001 actcgtgatg ggattacagc ccttcaaatg gatatcaaga ttcaagggat tactgcagaa
    12061 atcttgacgg aggctcttgc tcaagccaag aaagcgcgtt ttgaaatcct tgatgtcatt
    12121 gaagcaacca ttccagaagt tcgtccagaa ttggctccaa ctgctccgaa aattgatacg
    12181 atcaagattg atgtggacaa gattaagatt gtcatcggta agggtggaga aaccatcgac
    12241 aagattatcg ctgaaacagg tgttaagatt gatatagacg aagaaggaaa tgtgtctatc
    12301 tactctagtg accaagatgc tattaaccgt gccaaagaaa ttattgctgg tttggttcgt
    12361 gaagccaaag tggatgaagt ttaccgtgct aaagtcgttc gtatcgagaa atttggtgcc
    12421 tttgttaacc tctttgataa gacagatgcc cttgttcata tctctgagat ggcttggact
    12481 cgtaccaatc gtgtagagga tttggtagaa atcggggatg aagttgatgt taaggttatc
    12541 aagattgatg aaaaaggccg tatcgatgcc tctatgaagg ctcttctacc tcgtccgcca
    12601 aaacctgagc atgatgaaaa aggtgaaaag tctgagcgcc ctcaccgccc acgtcatcac
    12661 aaggatcaca aacctaagaa agaatttaca gaaacaccaa aagattcaga gtaagaaaag
    12721 gagaaatgta tggggtggtg gcgcgaaacc attgatatcg taaaagaaaa tgatccagcg
    12781 gcccgcacca ctttggaggt tttgctgact tatccaggtg tcaaggcctt ggcggcccac
    12841 cgtctctcgc attttctctg gaagtacgac ttcaaactct tagctcgtat gcacagtcag
    12901 ttttggcgct tttggactca gattgagatt catccaggag cccagattga ttcaggtgtc
    12961 tttattgacc atggttctgg tctggtgatt ggagagacag cgattgttga aaaaggcgtt
    13021 cttctctatc acggagtgac tctcggggga acagggaaag actgtggcaa acgccatccg
    13081 actgtacgaa agggagccct catatcagcc catgcccaag ttatcgggcc tgtggaaatt
    13141 ggtgaaaatg ccaaggtcgg tgctgcagca gttgtcgtag cagatgtacc tagtgatgtg
    13201 acggttgtcg gtattccggc caagattgtc cgtcttcatg gtaagaaaga tgagcctgtt
    13261 attcacgaag tcgaagaaaa acgggagtat tatgtcaata aactcgagca ggctaaagat
    13321 gccagtcaca gatcgtctgg tttgtagagg atacctatat gattcaagca agaaacaagt
    13381 taagccaaga agagctatct gaggcgaaaa aagtaattaa ctgttgccaa aactatgacg
    13441 gtacctatcg cgatccctat ctctctaaca tgcttaattt tgatccaaac atgcccgcct
    13501 ttttccttta ttatgaaaaa ggcgaacttg ttggtttatt aactgtctat gcagatgaca
    13561 aagatgtaga agtgacgata ctggttcatc caggtcatcg ccgtcagggg attgcgcgtg
    13621 cattgtttac tagttttgag agaggaacag cttctttccc cattcggtca gtcacttttc
    13681 agacagaacg tattttttta gagaatcatc ctgactttgc cagtaactgg ggactaatag
    13741 aggatgaaga gacagaaact tggttaggta aggatagaag accttatccg ttagcaaatg
    13801 tttcccatct tgaagttttg ttagcagata gttcgtatca ggatcaaatt agtcaattaa
    13861 aatttcaggc attttcagag gaacatgaat cgagagaagt tgtggataga tatgtcgctg
    13921 aagctctgaa ggatccagaa agtcgcttat atattttatt aaaagacggt caggttattg
    13981 ggacttgtac ggttgattta tcgactaata cgaattactt ctacggttta gcaatattgg
    14041 aacctgaacg tggaaaaggc tatggaagct acttagcaaa atccctcgtc aaccaactaa
    14101 ttgagcaaaa tgacaaggaa tttcagattg cagtggaaga tagcaatgta ggtgccaaac
    14161 gtttgtatga aaaaattggc tttgtcaaac agactcaggt ggtttatctg aatgagaaag
    14221 gagcaaggga ttccgaagtg tagagatatt cggactgaaa tttacttgaa cttttagtga
    14281 tgaaactaat tgttcttgga tttcagcttt cctgattatg atttatgatt aaaatctatg
    14341 acaccatgtc tcgtgatttg cgagaatttg tcccgattga ggacggcaag atcaagatgt
    14401 atgtttgtgg gccaacggtg tacaactata tccacgtggg aaacgcccgt tcgacggtag
    14461 cttttgatac gattcgtcgc tattttgagt accgtgggta taaggttgcc tatatttcca
    14521 attttacaga tgttgatgat aagattatca accgtgccag ggaagaaggc atcacgcctc
    14581 aggaggttgc ggataagtac atcgctgcct ttcgtgagga tgtgacggcc ttgggcgtga
    14641 aacctgcgac tcgccatccg cgtgtagtgg agtttatggc agacatcatc cgttttgtgg
    14701 aagacttgat cgagaaaggc tttgcctatg agagtcaagg ggatgtctat ttccgtgtag
    14761 aaaaatccca caactatgct aaattggcta ataaaacctt ggaagatttg gagctaggtg
    14821 cttcaggtcg taccgatgaa gaaacggctc gtaaggaaaa tcctgtagac tttgctctat
    14881 ggaaatcttc caaaccaggt gagatttctt gggatagtcc ttggggacct ggacgtccgg
    14941 gttggcatat tgagtgttca gtcatgtcga cagagatttt aggtgatacc attgatatcc
    15001 acggtggtgg agctgaccta gagtttccac accacaccaa tgaaattgcc caatctgaag
    15061 ctaaaacagg caaggctttt gctaactact ggatgcacaa tggctttgtc aatatcgaca
    15121 atgtcaaaat gtctaagtcc ttgggtaact tcattacggt acacgatgcc cttaaaactc
    15181 ttgatgggca agtacttcgt ttcttctttg cgacccagca ctaccgtaag cctatcaact
    15241 tcacggaaaa ggcagttcgc gatgccgaga ccaatctcaa gtatctgaag aatacttacg
    15301 aacaaccatt tacaggaaac gtggatgccc aagagttaca aaactttaaa gataagtttg
    15361 tagcagctat ggatgaagat tttaatgctg ccaacggtat cacagttgtc tttgaaatgg
    15421 ccaaatggat caactcaggg aactatgatg caagtgtcaa gcaagctctt gcagatatgt
    15481 tagaaatttt tggaattgtc tttgttgagg aagttttgga tgcagagatt gaagacttga
    15541 ttcaaaaacg ccaagaggcg cgtgccaatc gagactttga gacagcagac caaattcgtg
    15601 accaattggt tactcaagga attaagctcc ttgataccaa ggatggagtg aggtggacac
    15661 gtgattgatg tcaatctcat taacgggatt gcgctagcct ttgaggggga tgcggtgtat
    15721 tctatgtata ttcgccgtca cctcatcctc aaaggtatga ccaaacccaa taaactccat
    15781 caagaagcaa ccaagtatgt gtcagccaag gctcaggctc gcctgattgc tctcatgttg
    15841 gaggagcagg tcctaacgga aaaagaagaa gaaatctaca aacgtggccg caataccaat
    15901 agccacacaa aggctaaaaa tgcagatgtc gtgacttatc gtatgtccac gggatttgaa
    15961 gcggttatgg gctatctcca tatgactgag aatctggaac gtcttgagag tttggtttca
    16021 tggtgcatcc aaaaagtgga gggctagaac atgagggaaa aagaactaca agactggttt
    16081 cctgaggctc ggatttcaga ccaaccagta gagaaagagg gctatctcac gctcccttta
    16141 gcttctcagc agtggatttt gctggaggaa gctgggctca gcgagcgtga aaagcagttg
    16201 gttgcccttt tgacccagca ggagcaggct cgttcgctaa acccttggta ttcctatctg
    16261 gttgaaggca agggacaggc accgcaagtt tttaaaaaga ttcagttggt ttattgccat
    16321 ctttcttatt ttcagcagga aaatctggct tcttggctag atatgatgcg gactcttttt
    16381 ccgaattgtc agacagtgct acaggtcgga tctcaggatt atgttttcgt gcttcaacaa
    16441 gacaaataca cttctgtaag agatatttta agtgatacga ttgaagcggt tgagtatgac
    16501 tttggacttc gtctttctat catgttgggt caggtttggt ctcagacggg acatcaagcc
    16561 ctatcagact taatcaaagc tgagcgggat ttgttcaaga catggtggcg tcagggtcac
    16621 caaggtgttc atactttttc tcagctctat ctttggagta tgggagaaag actcgtggac
    16681 ttgaagccaa tcaaggaatg tctacaccag atgattttgg atcaagatca gattcaggaa
    16741 atcattctct ctctttggga aaatagtgct gttctcacta aaacagccca gcaactctat
    16801 ctgcaccgca attctctcca atacaagatt gataaatggg aagagttgac agggcttcag
    16861 ttgaaagagt tgaccgacct gaccttgtgt tatcaattga ttttaggttc tttgtcaact
    16921 atagttggtt tgtaaagaag ttaatatttg gagaagagga tggccatctt ctccattttt
    16981 atgtgcagag ttatagtggc ttgatgctgg gaaagtacac tgtgactgct aaaacattcc
    17041 tagaagttgc tttgatttcc ctaatctatt tatgtgaatt ttatgttatt ttactataac
    17101 agttgttgct aagctaaata atagtgggga agtttattta gacgtaagca ttgaagataa
    17161 tcagggaggt agtgggtata atttcagttc tgtttcaagt agctcacaaa cagctaaata
    17221 tgaaggaact ggttataata acaattcatc attatatata acgattgata aaacgtctga
    17281 tgcaacagct cttttgaaat taaagttgaa taatgttgat aatcaacctg ctactgaagt
    17341 tcctagttca ggaattactg taaaattaaa tgctaaagat aatgctggaa actggacaag
    17401 tgcttcgaat aaaaaagaag taacagtaaa aattgtttct gctaaaccga catatccaga
    17461 caaaatttta gtgaaaaatc ctgataatat aaaagataca gaaaaaaatg ccattattga
    17521 aaaattgaaa gaggcaaata aaaatcatcc agcaggagct ccaacctttg ctaaaggtga
    17581 aggagagcat gcaaatgata ttgtagcaac ttattcagat ggtacaactt attatgtacc
    17641 gttaaatgat gtgacaaaat atgcgaggta gtggctgtac cactcactta ttcacctccc
    17701 cgtgatttgt agtagtgata ggctttctca ctattattat aaaacaaaat aaagatcaca
    17761 acactttttc attctgtgtt gtgccttgag tgaaacgaaa ggaatgaatt ataaatatga
    17821 aaagtatagt cactaacata gatgagcgct tgcgtactcg cctacgagtg attatctgga
    17881 agcaatggaa gaagaaatcg agacgattat ggggattgct taagttaggg gttcctaaat
    17941 ggatagcaga taaggtatct ggctggggcg accactatca attatattaa aatgaaataa
    18001 gaataggacg aatcgatcag ggaagtcaaa tcgatttcta acaatatttt agaagtagag
    18061 gtata
//
LOCUS       DAVKBC010000038        16966 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVKBC010000038 DAVKBC010000000
VERSION     DAVKBC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16966
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.038"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            139..810
                     /gene="sdaAB"
                     /locus_tag="VWX64_001558"
     CDS             139..810
                     /gene="sdaAB"
                     /locus_tag="VWX64_001558"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU9191002.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            819..1691
                     /gene="sdaAA"
                     /locus_tag="VWX64_001559"
     CDS             819..1691
                     /gene="sdaAA"
                     /locus_tag="VWX64_001559"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU9191003.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            1713..2345
                     /locus_tag="VWX64_001560"
     CDS             1713..2345
                     /locus_tag="VWX64_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9191004.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLVPQQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            2395..2562
                     /locus_tag="VWX64_001561"
     CDS             2395..2562
                     /locus_tag="VWX64_001561"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191005.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKVVDRTDEVSSKHCFEVVDRTDEVS
                     NHIRQGDVDVV"
     gene            complement(2648..4498)
                     /locus_tag="VWX64_001562"
     CDS             complement(2648..4498)
                     /locus_tag="VWX64_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9191006.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIVFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(4537..5697)
                     /locus_tag="VWX64_001563"
     CDS             complement(4537..5697)
                     /locus_tag="VWX64_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9191007.1"
                     /translation="MSSKVSGFQDKNGKVWKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLYQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNMLQ"
     gene            5755..6921
                     /locus_tag="VWX64_001564"
     CDS             5755..6921
                     /locus_tag="VWX64_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU9191008.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            7060..7386
                     /locus_tag="VWX64_001565"
     CDS             7060..7386
                     /locus_tag="VWX64_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9191009.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            7373..7966
                     /locus_tag="VWX64_001566"
     CDS             7373..7966
                     /locus_tag="VWX64_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU9191010.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            7959..8870
                     /locus_tag="VWX64_001567"
     CDS             7959..8870
                     /locus_tag="VWX64_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU9191011.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDFITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            8932..9996
                     /locus_tag="VWX64_001568"
     CDS             8932..9996
                     /locus_tag="VWX64_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191012.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFKALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(10174..11034)
                     /locus_tag="VWX64_001569"
     CDS             complement(10174..11034)
                     /locus_tag="VWX64_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU9191013.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(11309..12295)
                     /locus_tag="VWX64_001570"
     CDS             complement(11309..12295)
                     /locus_tag="VWX64_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU9191014.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(12567..14042)
                     /locus_tag="VWX64_001571"
     CDS             complement(12567..14042)
                     /locus_tag="VWX64_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU9191015.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(14252..15175)
                     /locus_tag="VWX64_001572"
     CDS             complement(14252..15175)
                     /locus_tag="VWX64_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9191016.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(15189..16118)
                     /locus_tag="VWX64_001573"
     CDS             complement(15189..16118)
                     /locus_tag="VWX64_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9191017.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(16437..16658)
                     /locus_tag="VWX64_001574"
     CDS             complement(16437..16658)
                     /locus_tag="VWX64_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191018.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(16612..16872)
                     /locus_tag="VWX64_001575"
     CDS             complement(16612..16872)
                     /locus_tag="VWX64_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191019.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT         5033 a         3670 c         3194 g         5069 t
ORIGIN      
        1 ctaaataagg tgttttttgt cataaaagat actattttta tgctatttga ggtattagaa
       61 aggttttcat ccacaattaa agccaagccc ctcattcttt gatataatag agataagaat
      121 ttttataagg ggaaactgat gaaatcactt cgttttcaat ctgtctttga tatcatcgga
      181 ccagttatga ttggcccatc tagtagccat accgctggtg ctgttcgtat tgggaagatt
      241 gtctcttcca tttttgatga tactccgaca gaagttgaat tccaactttt taactcattt
      301 gccaagacct atcgtggtca cggaacagac ctagcccttg ttgcaggtat tttaggaatg
      361 gatacagatg atcctgaaat tccaaatagt ctggaaattg cccacaagcg tggtatcaag
      421 attgtctgga ccattcagaa agacagcaat gcccctcacc ctaacaccac taaaattact
      481 gttaaaaatg cccacaagac catcagcgtg actggtattt ctatcggtgg aggaaatatt
      541 caagtaaccg aactcaatgg ttttgccgtc tctctcaata tgaatacacc gactatcatc
      601 atcgttcatc aagatattcc aggtatgatt gcccttgtta cagaggcgct ttcccgctat
      661 ggtatcaata tcgcccagat gaatgtcact cgtgaaaaag ctggtgaaaa agccattatg
      721 attatcgaag ttgacagtcg caactgtgat gaggctatcg aagaaattcg aaaaatccct
      781 catctccaca atgtcaattt ctttaaatag gaggaagcat gttttattct atcaaagaat
      841 tggtcgagca agcagatctg gactttcaag gaaatgtcgc agaactcatg attacaacag
      901 agtttgaatt gaccggtcgc gaacgtgaag aagtcttcct tctcatggaa cgcaatctgg
      961 aagttatgaa agcctctgtc caacttggcc tcaatgaaaa taaatctcgt agtggcctga
     1021 caggtggaga tgctgccaaa ttggatcact acatcgaaaa cggaaaaact ctgtcagatt
     1081 atacgattct ctcggctgcc cgaaatgcca tcgcagtcaa tgaacacaat gccaaaatgg
     1141 gcttggtctg tgccactcca accgctggaa gtgctggctg tctgccatcc gttctcactg
     1201 ctgctattga aaaattagac ctcagccacg agcaacaatt ggatttcctc tttgctgctg
     1261 gtgcctttgg actagtcatc gcaaacaatg cctccatctc aggtgctgag ggtgggtgtc
     1321 aagctgaagt tggttcagcc tctgctatga gtgctgccgc cttgactctg gctgcaggtg
     1381 gaacacctta tcaggccagt caagctattg cctttgtcat taaaaatatg ctaggcctca
     1441 tctgtgaccc tgttgcaggt ttggtcgaag ttccctgtgt caaacgtaat gccatgggag
     1501 ctagctttgc tttcatcgca gcagacatgg ccttagcagg tatcgaatct aaaatccctg
     1561 tggatgaagt gatcgatgcc atgtaccaag taggagcaag catgccaact gcctttcgtg
     1621 aaacagctga aggtggactc gctaccaccc ctactggtcg tcgcctccaa aaagaaattt
     1681 tcggagaata agcttatcaa ataggagaaa ccatgacctc tatcacagcg atttttttcg
     1741 atttggatgg aaccctcgtt gatagttcta tcgggattca caatgccttt acctatacct
     1801 ttaaagagct gggggtgcct agccctgatg ccaaaactat tcgtggtttt atgggaccac
     1861 ctctcgaaag tagttttgcg acctgcctgt ccaaagacca aatttctgaa gccgtgcaga
     1921 tatatcgttc ttactataag gcaaaaggca tctatgaagc tcaactcttt cctcagatta
     1981 tagacttgct tgaggagtta tcgagcagtt atccactcta catcaccacg acaaagaata
     2041 catctactgc tcaagacatg gcaaaaaact tggaaatcca tcatttcttt gatggcattt
     2101 atggttctag ccctgaagca ccccataagg cagatgtcat tcaccaagcc ttgcagacac
     2161 atcaactagt ccctcaacaa gccatcatca tcggagatac caagtttgat atgctgggag
     2221 ctcgagaaac aggtattcag aaattggccg tcacttgggg atttggagag caagcagatc
     2281 tactaaacta tcaacctgat tatatcgctc acaaaccctt agaggttttg gcgtattttc
     2341 aatagcatag actgggtaac aattccattt cagaagaaaa tgaagtaata ctcaatgaaa
     2401 atcaaagagc aaactaggaa actagctgcg ggctgctcaa aacactgttt taaggttgta
     2461 gatagaactg acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa
     2521 gtcagtaacc atatacggca aggcgacgtt gacgtggttt gaagagattt tcgaagagta
     2581 taagtctcta cataataaaa cgcatattac caaggttgtg taacttgata ctatgcgttt
     2641 ttctttttta ttcaatgtgg gttgtttgat tagcaaaggc gataatagct tgcttcaact
     2701 catctccact gagagtgcgg aactctccaa tcttttgatt gatggattct aaaggcatga
     2761 cattaacctt accaacgaaa atcttatcca taacttgatt atcaacgagt tcggttgata
     2821 ccaagagttc ttcgtagagt ttttcacctg ggcggattcc aacttcaacg attggaattt
     2881 cactttcagt gtggccactt agaagcacca tcttcttggc caagtcataa atcttgactg
     2941 gtttgcccat atcaaggata aagacttccc catctttggc ataagcacca gcatggataa
     3001 ccagacggct agcttctgga atggtcataa agtaacgggt catgcggaag tctgtcaccg
     3061 ttacaggccc accttcagca atctgacgtt caaagactgg aatgacacta ccacggctac
     3121 caagaacatt cccaaaacga actgcacagt aggttgattg gctacgttgg ttaaagccag
     3181 tgacaatcaa ctccgccacg cgcttggttg ctcccataac atttggtgga ttaactgcct
     3241 tatctgtcga aatcataacc atcttaggca ccttggcttc atcaacggct ctagcaacat
     3301 tgtaagttcc acggatattg tttttgaagg cttcttttgg attgcgctcc atcataggaa
     3361 catgcttgtg ggctgccgca tgataaacaa tagcaggttt gtactgctca aagacttgca
     3421 acaaacgatc atagtcttga atgtccgcaa tcacaggtac ataatcaatc ccttggaact
     3481 tacgaatcaa ttcatgataa acaaggtaga ttgagttttc cccatgaccg agcaagacaa
     3541 tgcgttcagg attgaagcga ctaacttgac gacagatttc agaaccgatt gaacctccag
     3601 ctcctgtgac taagatggtc ttacctgtca gttctgcacc cagacgcgat tcgtcaagac
     3661 ggatttcctg acgacccaaa aggtccgtaa tatcaatttt ttggaagcca gtacctgctt
     3721 ggtgaaggcc ctgaacaaca gtttcaacct taggcatctt gtaacatttg acacccagct
     3781 tattacacat ctgcaagata cgctcatatt ctgacggatc cagcgacgga atcgcaacga
     3841 tgacacgctc gatttgatgg cgtttggcta attcaggcag attgtcataa gagcccaaaa
     3901 caggaatacc accaagtttt tgaccctttt tcttagaatc cttatccaaa ataccgacca
     3961 gttctaattc actggttgga tgttggtaac tatccataaa gagagcccca ccatcaccgg
     4021 caccaatcaa gaaggtccga cggtgttctc catcaccact accttttttg cgtctggagt
     4081 agattaactg ccaagtaatc cgtggcaata aaatcaagaa ggtactcaac aagataaaga
     4141 gaatgatgaa acggatggag aagagtggca agaaggcata acagatacta tatgacaaga
     4201 cactgctagc agtcacacca aaaaagattt tcatgaaatc cgtaatcttg ctgtaacgac
     4261 taatgctcgc gttcaacccc caaaaaacaa tcatcaattg atagaacaag aaggccaaac
     4321 tcgtatagat aatgtagtca acaggtgctg gattaatcag cccataaaat aaaatataag
     4381 atacaatgat ggaaaccacc atactgaaaa tatcaaatat tccccagaaa acctgctttt
     4441 gttgtttatt taaaatttcc accagatcaa tcacataatc tgttagtttt ttattcatag
     4501 aaatctactc ctccttaaaa gagttttact atattgttat tgtagcatat tttgatttat
     4561 ttggcttatt ttatccaaat aaattattgt tcccttgtac tccttcttcc atttaaatcc
     4621 tctaattaaa cctacaatcg tcccaaagcc ataagcaaag tgaatggaaa ataaaagaaa
     4681 gggcatcaca attagaaatc catttttatg ttttaataaa gtcagcaaag tgagtagtga
     4741 caaaagtaga aaataggcac ctaatagtaa agttatgaat acgaatgtga tcggtaacaa
     4801 tgctagacta aacacaagac tcaaaacaaa taaacaagga acatagtgaa ataatgataa
     4861 acacttaaac tgaacatgac ttgtcaagcc aatccacaaa ccatttgaat acttttgata
     4921 cagcattttc ttgaatgttg gtcgaatata ctgataagat agaatacttg ggctatagcg
     4981 aattttataa ccatgttctc gaattctata atgaatatca ttatcttcag ttcggccaag
     5041 ttgctcattt actaaaccaa ccttctggaa aacctctcgt ttatacatcc catgaaaaat
     5101 agaagaaaca tatctatctt cggaactatt tcgataattg gcaatactac tgccaaacat
     5161 attttcctca acaagatgca aggtctctgc ccattttcct tttccttcga caatcgtcgg
     5221 tctaggcccc ccacagacaa attcaccttg ttgaataata gccacattgt tcattacaaa
     5281 actctcagta acttttgaat gagcatcaat ttttaaaata aggtccccta cagaatgttt
     5341 aactcccagg ttaaaaccac tagcttgatt tttcttagga ttgttataca atctaattga
     5401 gttaaactct gtatcttcct ttataaattg ctgaatgata gctgtggtcc catctgtgga
     5461 catagcattt ataaatagaa tttcaatatt ctctttagga taagtttgat tttttaagtc
     5521 ttcaattaga ccaggcagat atttttcttc attgtatgca ctgattacaa tggatacgag
     5581 aagactttca acattttgag tcactactac tctcctgaat ttttccttcc accattctat
     5641 cataattttc cagactttcc catttttatc ttgaaagcca gaaaccttac ttgacattat
     5701 agtgaaaaag ccttaaaata agctgttatt aaaatcagct agaagaggta ttatatgaaa
     5761 aagcaatcac tcttttttgt tccaggtatt atcctgattg gtgtttcctt gcgaactcct
     5821 tttactgttt tacccattat tttgggaaat atttcgcaag gtctggaggt agaagttagt
     5881 tcgcttggtg tcttgaccag cctgcctctc cttatgttta ccctcttttc accattttct
     5941 acccgactgg ctcagaaaat cggcttggag catctcttca cctacagcct cttcttcttg
     6001 actatcggct cacttattcg actaatcaat ctgcccctgc tctatctagg aaccttgatg
     6061 gttggggcaa gtgtcgcagt catcaatgtc ctgcttccta gtcttatcca agccaatcaa
     6121 ccaaagaaaa ttggttttct gaccacctta tatgtaacgt ctatggggat tgcaacggct
     6181 ctggcttcct atctagctgt gcccattaca caagccagtt cttggaaagg acttatcctt
     6241 ctcctcacgt tactctgtct agcaactttt ttggtctggc tcccaaatca ccgctataat
     6301 catagactag ctccacaaac caaacaaaaa agtcaaataa aggtcatgcg taataaacag
     6361 gtttgggcaa ttattatctt ttcaggtttt caatccttga tcttttacac cgtcatgacc
     6421 tggttaccta ccatgtctat ccatgcaggt ctatccagtc acgaagctgg cttgctgact
     6481 tctatcttat ctctgattag cattcctttt tcaatgacca tcccaagcct gacaaccagt
     6541 ttatctactc gcaaccgtca gctcatgctt actctggttt cactagctgg tgtggtcggc
     6601 atttccatgc tctttttccc aatcaataat ttcatttact ggcttgccat ccatctcctc
     6661 atcggaaccg caaccagcgc cctcttccct tatctcatgg tcaacttttc actcaagaca
     6721 agcgcccctg aaaagacagc ccaattgtcc ggcctatctc aaacaggagg ctatatccta
     6781 gcagcctttg ggccaaccct ctttggttac agttttgacc tgttccactc ttgggtacca
     6841 tctgtagctg ccctcttgct catcgatatc ctgatgactg tggccctctt tacagtggac
     6901 agagcggata agatccttta aacttctagt tttagctaga agttttttat atataaaaat
     6961 tttacacatt tctcttgaca gggctttctt ttagatgtac aatgtatgtg tagaaaaatt
     7021 atatataaaa atcttacaca ttagaaaagg aggtttccca tgtactttcc aacatcctct
     7081 gccttgattg aatttctcat cttggccgta ctggagcagg gtgattctta tggttatgag
     7141 attagccaaa ccattaagct aatcgctaat atcaaagaat ccacactcta tcccattctc
     7201 aaaaaattgg aaggcaatag ctttctgaca acctattcta gagagttcca aggtcgcatg
     7261 cgcaaatact actccttgac aaacggtggt atagagcagc tcttgaccct aaaagatgaa
     7321 tgggcactct atacagacac catcaatggc atcatagaag ggagtatccg ccatgacaag
     7381 aactgaatac ctgactcagc tagaactcta tctcaagaaa ctacctgaag ctgaccgtat
     7441 cgaagccatg gactatttca gagagctctt tgacgatgct ggagtcgaag gagaagaaga
     7501 actcatcgct agtttgggaa ctcccaaaga agcggcccac gaagttctat ccaatcttct
     7561 cgataaaaaa atcaatgaag cacccgctca aaaaaataac cgacaaattt tacatatcgc
     7621 cttgttagcc ctccttgcag cacctatcgg cattcctctg ggaatcgcca tcctcgtgac
     7681 cctgttcgca atccttgtag ccgctttgac tgtcattctg gctttctttg cagtttccat
     7741 actgggtatc atcggcggat tcctattttt agttgaaagt ttcactatac tcgcccaagc
     7801 caaatcagcc tttatcttga tttttggttc tggtttactg gctatcggtg cttcttcgct
     7861 agttttactt ggcatttcct atgtagctcg cttcttcggt ctactcattg ttcgtctggt
     7921 acaatttgtt cttaaaaaag gaaagagagg taatcagcat gcgtaaatgg acaaaaggat
     7981 ttctcatctt tggtgtggtg actaccgtta tcggctttat cctgcttttt gtaggtatcc
     8041 aatctgacgg gattaagagt ctactttcca tgtccaaaga acctgtctat gatagccgta
     8101 cggaaaagct aacctttggc aaggaagtcg aaaacctaga aattactctc caccaacaca
     8161 cgctcaccat cacagactct ttcgatgatc aaatccacat ttcttaccat ccatctcttt
     8221 ctgctcacca tgattttatc accaatcaga acgatagaac tctgagtctc actgataaga
     8281 aactgtctga aactccgttt ctctcttctg gaattggtgg gattcttcat atcgcaagta
     8341 gctactctag tcgttttgaa gaagttattc tccgactacc aaaagggaga actctaaaag
     8401 ggatcaacat ctcagccaat cgcggacaaa ccaccatcat aaatgctagc cttgaaaatg
     8461 cgaccctcaa tacaaacagc tatatcctcc gaattgaagg aagtcgtatc aaaaacagta
     8521 aactcacaac gcccaatatc gttaatatct ttgatacagt tcttacagat agtcagctag
     8581 agtcaacaga taatcacttc cacgctgaaa atatccaagt ccatggtaag gttgaactga
     8641 ctgccaaaga ttatctcaga atcatcctag accagaaaga aagccaacga attaactggg
     8701 acatctcaag taactacggt tctatcttcc aattcacaag agaaaagcct gaatcaagag
     8761 gtacggaatt aagcaaccct tacaaaactg aaaaaaccga tgtcaaggat caactcattg
     8821 cgagatctga tgataatatt gatctaatat ccacaccaag cagacgttga caaaaacgct
     8881 tacatctgct actatggaag catatttatc taaccaaaag gaggttctac catgaaacaa
     8941 gaatggtttg aaagtaatga ttttgtaaaa acaacaagca agaacaagcc tgaagagcaa
     9001 gctcaagagg ttgcagacaa ggctgaagaa acgatagccg atttcgatac accaattgga
     9061 aaaaatactc aagtagagga ggaagtctct caagctgaag tcgaactgga aagccagcaa
     9121 gaagagaaaa ttgaaactcc tgaagtcggt gaagcgagaa cagaaataga agaaaagaag
     9181 gcatctaatt ctactgaaga agagtcagac ctttctaaag aaacagaaaa agtcactata
     9241 gctgaagaga gccaagaagc tcttcctcag caaaaagcaa ccacgaaaga gccacttctt
     9301 atcagtaaat ctttagaaag tccttatatc cccgaccaag ctccaaaatc tagggataaa
     9361 tggaaagagc aagtgcttga tttttggtct tggctagtgg aagcgatcaa atctcctaca
     9421 agtaagtttg aaacaagtat cacacacagt tacacagcct ttctcttgct cattctgttt
     9481 tctgcatctt cctttttctt tagtatctat cacatcaaac atgcttacta tggacatata
     9541 gcaagcatta acagtcgctt ccctgagcag ctagctcctt taactctttt ttctatcatc
     9601 tctatcctag tagcgacaac actcttcttc ttttcattcc tcttgggtag tttcgttgtg
     9661 agacgattta tccaccagga aaaggactgg acgctagaca aggttctcca acaatatagt
     9721 caactcttgg caattccaat cttcctcact gctattgcta gtttctttgc tttctttgat
     9781 agcctacgat ttaaagccct cttgtgtgtg attagcattg gaatcattct gcttgccagt
     9841 ctccatatca ttacaagacc aagtcaagca agtgaaaccg actccttcta tcaattattc
     9901 ttgtctgtcc ttgtgaacgg agttattatc ctcctcttct ttgtagctga agtggcactg
     9961 attggagatt atcttcgtat cttggccttt ctttaaaatt catactcttc gaaaatcaaa
    10021 ttcaaaccac gtcagcttcg ccttaccgta ctcaagtaca gcctgcggct agcttcctag
    10081 tttgctcttt gattttcatt gagtagcaat cctgtcatcc ttggcaggat tttttctatg
    10141 tcaaaaaagc aagtcgattg acctgcttct gctttacttt tcttgtgcta atgttttaaa
    10201 atcttgtcct aggatgggtt gtatttctat ttgattggcg tctagttggt ggtaaaaaga
    10261 tgggggtaat acctctaaga attttgcata gtccaagcga gctatggatt catagtcttc
    10321 tggtttagag ccgtctcctg tgatttgaac caagtcaatc tcccactgga cttccttatc
    10381 caccaattgc tcaatatagg ctgcaggaac aaacggttct ctcggtaaaa ctgtcttgac
    10441 tccttgagct agatggtaaa cgccatgcac ttttccttct ccatcctgat agaaggaaac
    10501 tctcgcaaag taggcatctg tctcttgaac cgcacgcaca cgcgcttcaa actgagccaa
    10561 gccatctgcc tctaaaaagc ttttcaagtt ctcacgacta aagaaaatag gattaaaaat
    10621 tccttggcaa atcgtaaaac gagctacagg gtctgctaga taggcttgaa tacttgcttg
    10681 gaaataagct tcaaaatcaa aaccatctag cccttcaata tcagtccctg tataagcaag
    10741 caaagcatct aaaaatgact tgataatctg ccagtctgtc tttgttagta ggtcaggaag
    10801 atcgacacgg taagcctttt gaccatcagc ataactgacc ttaaaaagaa attgtgattg
    10861 ccccactatc gcacactcaa tatactcgag acgattaaga ggctgacgga gatagactac
    10921 atcatagcta tgtgactcca aaccgtctag caaggccaag atcgacttgg cattcaaaat
    10981 ctcttgttct cctaaaatgc tctgtttatt tggaataaaa aatgtttttg ccataactgg
    11041 actcctttga aatcgtttac atacagtata ccttattttt ctgaaagata cagaaacaaa
    11101 ctttatactc ttcgaaaatc tcttcaaacc gcgtcagctt cgccttgccg tagatatatg
    11161 taactgactt cgtcagtctt atctacaacc tcaaagcagt gctttgagca gcctgcagct
    11221 agcttcctag tttgctcttt gattttcatt gagtattaga tttttgagta caaagcatag
    11281 aaaaacagcc cctgaggact gtttgatctt atacagtagc tgcttgatcc aagctttcac
    11341 cgatagcggc taggcgctcg atcacttcag cttgtgtcaa ttcatttttt gaaacatagc
    11401 ggttacgtgg gtgaacacgg cactcgtgtg agcatccacg aaggtacttg tcttcatttt
    11461 cttccgatgt caagatacga cggttacaga atggatttcc acagttgaca taacgttcac
    11521 atggtgttcc atcaaaccag tctttcccta cgatagttgg gttgacatgg ttgacatcaa
    11581 cggcaatacg ctcgtcaaag acgtacattt tcccatccca aagctcacct tgaacttctg
    11641 ggtctttacc gtaagttgcg attcctccgt gcaattggcc gacatctttg tagccttcac
    11701 ggaccatcca gcctgagaat ttctcacagc gaacgccacc tgtacagtaa accacgacac
    11761 gcttgtccat gaatttttcc ttgttatcac ggacccattg tggtaactca cggaagttgc
    11821 gaatatctgg gcgaatagcc ccacggaaat gtcctagatc gtactcataa tcgttacgtg
    11881 tgtcaaggac aacggtatct ttatcaagaa gcgcttcttt gaactctttt ggagacaagt
    11941 aagcacctgt tgtttcaagt gggttgatgt cattgtcaaa gtcgttgtct tccaaaccaa
    12001 ggtggacaat ttctttcttg tagcgaacaa acatcttctt gaaggcttgt tcattttctt
    12061 cgtcaatctt gaaccagaga tcttccatac ctgggaggct gtgaacgtag tccatgtatt
    12121 tttgagttgt ttcatagtca cctgaaactg ttccgttaat tccctcatca gcgactagga
    12181 tacggccttt aaggccgatt gatttacaga aagccaagtg gtctgcagca aattgctctg
    12241 cattttcaat tggagtataa aggtagtaaa gtaagacacg aatatctttt gccataagat
    12301 ttgttctctt ttctattctt aaattttcta aattttttat ttatctacac tagtatacct
    12361 gcttgagaaa acgaatgcaa tttatttgac tggaaattgt agagggttct cgaaatttcc
    12421 tgaatggtta aaataaggac aagagaaaac atggatatct atatccttgt gccaaaaaaa
    12481 ccactgccct ccccagacca acctgaggaa agcagtgatt cttattttag gagttaggaa
    12541 tgaatacacg aaatcaattt agctgattat tttttgtttt tcaagaattc atcgtattgt
    12601 ttttgcattt cgttcaatac tttttcgtag gcaccttcag atttcaattt ttccatcaat
    12661 tctggaatcg ctttatctgg gtctacagta ccagtgttga tagctgtatc aaattgttgc
    12721 attgtgttag caatagctga gatttcagat ttcacattgt cagtattaaa gataaatcca
    12781 agcgctggag attctttagc ttctgccaat tctttcttag aattttcgat ttgttggtct
    12841 gtaacgtttt cgttgatgta aaggatccag ttgttaccag tgttccatcc acccatgtga
    12901 gtgtttcctt tgtagccatc aagaacgcga acacggtttt ctttaccttc aattttttcc
    12961 cagttcttgc cttctggacc gtaaacaaga ccgttcaaga gttctgggtt ggtattcaag
    13021 aggttcaaga tttccattga tttttctttg ttcttagagt tgtttgagat gacaaagtta
    13081 gcaacttgtg ttgtttggtt tttcttgatg aagttagtaa ttggtttgat ttggatatct
    13141 ttgttggcaa cacgtgaaag caagctgtta ccgtagtcag ctggtcctac tgtttcttca
    13201 cgaacgaacc aagtatcttg ttgaaggtca aaggaagtat cgcttgttgc gacgtctttt
    13261 ggaatgtagc cagcttcata gaatttgtga agagtcttca agtgttcttt gaaacgaggc
    13321 acttcgtaac ggtttacaac tttagtagta tcgccttcaa ggtcgataac gaatggaaga
    13381 ccgtttgcta ctgggtagtc aaagttatca gatgggatga aaactttacc aatagcaaat
    13441 ggtactacgt ctggagcttt ttctttaatt tgtttcaaga ctggctcaag agtttcgtaa
    13501 gaagtaacac ctgaaatatc gataccatat ttagcaagga gagttccgtt gaaggcaaag
    13561 ttttgagatg acgcaacgtt ggctgcaact ggtacagcat aaatcttacc atttacagta
    13621 ttacccttga tataagctgg gtcaagtgcc ttgtaaaggt ctttaccttc ttttttgtac
    13681 aattctgtca agtcagcata agcacctttt tgagcattta caatatagtt atctgcaaag
    13741 gcgatatcat agttttcacc agatgatgtg ataactgaca ttttcttacc atagtcaccc
    13801 cagccaaggt attggatatc caatttagca ccaacttttt cttcgatgat tttgttggca
    13861 tttgctaaca attcatccaa gttatctggt ttgtcaccga tttggtacat tttgataaca
    13921 ggtttgtcac ctgaatcagc agctttttta ctgttacctg tcaagttgcc acaagcagca
    13981 agacctgcag ccaaagcgac tacactagca gatgcaaaag catatttttt ccagtttttc
    14041 atgataaaaa ctcctttttt tatttttaaa cttataaaca atgtaatgat cttatactca
    14101 atgaaaatca aagagcaaac tagaaaacta gccgcaggct gtacttgagt acggcaaggc
    14161 gacgttgacg cggtttgaat ttgattttcg aagagtatta acttcacaca agggaagttg
    14221 ggaactgaga aatgttcttt ttcaataagc actattcttt cacaccaccg atagtcaaac
    14281 cttttacaaa gtagcgttgg aagaatggat acaaaatcgc gattggaagg gttgctacca
    14341 caaccatggc catacgacct gtttctttcg gtagagcaac tcccagttga ccagtcaagc
    14401 cgaccgcttt ggcaatgtag tccatatttt gttggatttg catgagcaaa tattgcaatg
    14461 gatacaagtt atcactcttg atgtaaagaa gggcgttgaa ccagtcattc cagaaaccaa
    14521 gagctgtcaa aagcgtgatg gttgcgatac ctggtagtga caatggcaaa cagatttgga
    14581 agaaaatccg agcctcactg gcaccatcga tacgagccga ttcgagaatg gcttctggaa
    14641 tggtcttctt gaaaaaagaa cgcatcaaga tgatattgaa tggtgagaga agcattggaa
    14701 caatcaaggc ccaaacagtg tcaccaagct gaagtacacg ggtcaccatg atataacctg
    14761 gtaccaaacc agcgttgaac aacatactga gaaggacgaa gatggtaaaa aatctgcgat
    14821 acttaaaggt tgtccgtgaa atagcgtagg cataggttgt tgtgataaag acatttgtca
    14881 atgtcccaac tacggttaca aagacagaga tgaagagggc ttgtaggatt ttatccttaa
    14941 actgtgccaa aaactcaaaa ccgtctaagc caaattggga tgggaagaag ctatagccgt
    15001 attggaggag gcttttctcg tctgtcactg aaataatgat aacgaataca aaaggtagga
    15061 tacaagagag ggcaatcaaa cccgaaatga tactgaagaa gatatctgct ttcttactga
    15121 aggagtgaat gccgacatta tcaatttttt cttttttaat tttctttttt gccatattct
    15181 cctcctttct agaacaaagc tgagtttgga tcgactcgtc ttgcaagcaa gtttgatagg
    15241 ataaccagaa tcaaaccaac aacggattgg taaagaccgg ctgctgcagc cataccgata
    15301 tctgctgtct gagtcaaacc attaaagaca tatacgtcca aaacgttggt tacattgtaa
    15361 agctgaccag cattgtgtgg gatttgatag aagagaccga aatctgcgcg gaagatattt
    15421 ccgactgcaa ggatggtcaa tacagttaca agcggagtca actgaggaat ggttacgttg
    15481 cgaatacgtt gccacttgct agctccgtcc actgtcgctg cttcgtagta ggttggatca
    15541 attcccatga tcgtcgcata gtacatgaca ctgctatatc caaagccttt ccaaatacct
    15601 aggaaaagta ggagataggg ccagatgccc aggtcagcgt agaaattgac ttctttgaga
    15661 ccaagacttt ccaatagatg attgaacacc cctttatcaa tatttaggaa ggcatctgta
    15721 aagaaactaa tgataaccca agacaagaag taagggaaca acatagaagt ttgaaaaatc
    15781 ttcaccattc tcttagaacg gagctcgctg aggataatgg caatccctac agatacaact
    15841 aaacctagaa agataaagcc aagattgtag aggacagtat ttcgtgtgat aataaaggcg
    15901 tctcttgaac taaataagaa tctgaaatta tcgagtccga cccatttact atttatgata
    15961 ctatctatga aaccattact ggtcatgtgg tagtctttga aggcaaccac gttcccaaat
    16021 actggaatgt aaaagaatag aatcaaccag agtgcccctg gcaaaaccat caagagaaag
    16081 atccagttgt ctctcaatgt ttttgaaaac tttttcataa tttcctccct ttttattttg
    16141 atatccatct aaaaattctt ttttagactt ttgataacga ttacattatt agtatactcc
    16201 tatttgcagg ttaggttaaa ctcctaatta tagaaaaaac tccacaaatt atgtagcaga
    16261 tttaaaactt tatcaccact atcaaacaaa tgtcctaaat caattgttta ttttatctct
    16321 attagcccag tgatggcgtc actctgttat aagcatccaa caacggggta tactgaaaaa
    16381 tctccagact agggaactca gagatagttc ctaatctgga gatttttaat atgttattag
    16441 gcgtttgctt tcaacttagc aataacctct ttaagattat caatcacctc tgcttcagta
    16501 tgctcagagc ctttttcatc tgccaagaac aaaactgctt tttgaagttc tttttgagag
    16561 ttttcaagga catccttatc tactgtttca aggtttgagt ctttaagaag tttacttaat
    16621 tccttggcta atttcttgag tttgatttgc agactcatct tctcctgctg tttctttgcc
    16681 cgctgtttgt cctccatcct tagttgctga ctggctttcc ttaatggact ctagggaagc
    16741 aatggcatct ttgactgttt gcaagatatc acgtaaacct tgctctgtca aactatcatc
    16801 tgcaaaagct ttcttagcct ctgccaaaac cagacgtgct gaatctgtgg taggattcga
    16861 tacacctgtc aatgatctca aaagattttc taaggtttga gtctgcttac taatactaga
    16921 ctaaaatcaa aaagtattat ataacagtga tatgaaatca actaaa
//
LOCUS       DAVKBC010000039        16737 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVKBC010000039 DAVKBC010000000
VERSION     DAVKBC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.039"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..481
                     /locus_tag="VWX64_001576"
     CDS             <1..481
                     /locus_tag="VWX64_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191020.1"
                     /translation="IMDINHLVFNKTEFLFNQNKWEKEDSFESDLTNTLKDKIQKSDL
                     SYSDLMSLLLYDAMNQSTFLTDSELFEDILKKIEDSHNTLLCTGLVELLLYEMSISNN
                     NNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNFDFCMNREYHKMKSRKLLLSNKKIV"
     gene            537..890
                     /locus_tag="VWX64_001577"
     CDS             537..890
                     /locus_tag="VWX64_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU9191021.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLAGAAGRIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            887..1615
                     /locus_tag="VWX64_001578"
     CDS             887..1615
                     /locus_tag="VWX64_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191022.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLISFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDTKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSI
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            2747..2986
                     /locus_tag="VWX64_001579"
     CDS             2747..2986
                     /locus_tag="VWX64_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191023.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            2971..3249
                     /locus_tag="VWX64_001580"
     CDS             2971..3249
                     /locus_tag="VWX64_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191024.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKITSCCIVASDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            3535..5412
                     /gene="pspA"
                     /locus_tag="VWX64_001581"
     CDS             3535..5412
                     /gene="pspA"
                     /locus_tag="VWX64_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEU9191025.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAMKNAEDAKKAVEDAQKALDDAKAAQKKYAEDQKKTEEKAALEKAASEEMDKAV
                     AAVQQATDKAAKDAADKMIDEAKKREEEAKTKFNTVRAMVVPEPEQLAETKKKSEEAK
                     QKAPELTKKLEEAKAKLEEAEKKATEAKQKVDAEHAEEVVPQAKIAELENEVQKLEKD
                     LKEIDESDSEDYVKEGLRAPLQSELDAKQAKLSKLEELSDKIDELDAEIAKLEKNVED
                     FKNSNGEQAEQYRAAAEEDLAAKQAELEKTEADLKKAVNEPEKPAPAPETPAPEAPAE
                     QPKPAPAPQPAPAPKPEKPAEQPKPEKTDDQQAEEDYARRSEEEYNRLTQQQPPKAEK
                     PAPAPQPEQPAPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGW
                     LQNNGSWYYLNANGAMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNASGAMAT
                     GWAKVNGSWYYLNANGSMATGWLQYNGSWNYLNANGAMATGWAKVNGSWYYLNANGSM
                     ATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEW
                     V"
     gene            5813..6934
                     /gene="mnmA"
                     /locus_tag="VWX64_001582"
     CDS             5813..6934
                     /gene="mnmA"
                     /locus_tag="VWX64_001582"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU9191026.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGYNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFALECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            7075..7530
                     /locus_tag="VWX64_001583"
     CDS             7075..7530
                     /locus_tag="VWX64_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9191027.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPGWEGQLRHIHLEE"
     gene            7540..9453
                     /gene="mnmG"
                     /locus_tag="VWX64_001584"
     CDS             7540..9453
                     /gene="mnmG"
                     /locus_tag="VWX64_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU9191028.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(9805..11484)
                     /locus_tag="VWX64_001585"
     CDS             complement(9805..11484)
                     /locus_tag="VWX64_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9191029.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(11486..11719)
                     /locus_tag="VWX64_001586"
     CDS             complement(11486..11719)
                     /locus_tag="VWX64_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU9191030.1"
                     /translation="MIYKVFYQETKERSPRRETTRTLYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            11999..12214
                     /locus_tag="VWX64_001587"
     CDS             11999..12214
                     /locus_tag="VWX64_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191031.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(12537..12689)
                     /gene="cibB"
                     /locus_tag="VWX64_001588"
     CDS             complement(12537..12689)
                     /gene="cibB"
                     /locus_tag="VWX64_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU9191032.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(12691..12876)
                     /gene="cibA"
                     /locus_tag="VWX64_001589"
     CDS             complement(12691..12876)
                     /gene="cibA"
                     /locus_tag="VWX64_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU9191033.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            13054..13737
                     /gene="tsaB"
                     /locus_tag="VWX64_001590"
     CDS             13054..13737
                     /gene="tsaB"
                     /locus_tag="VWX64_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU9191034.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            13734..14171
                     /gene="rimI"
                     /locus_tag="VWX64_001591"
     CDS             13734..14171
                     /gene="rimI"
                     /locus_tag="VWX64_001591"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU9191035.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            14161..15171
                     /gene="tsaD"
                     /locus_tag="VWX64_001592"
     CDS             14161..15171
                     /gene="tsaD"
                     /locus_tag="VWX64_001592"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU9191036.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKTFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(15337..15688)
                     /locus_tag="VWX64_001593"
                     /pseudo
     CDS             complement(15337..15688)
                     /locus_tag="VWX64_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15795..16088)
                     /locus_tag="VWX64_001594"
                     /pseudo
     CDS             complement(15795..16088)
                     /locus_tag="VWX64_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            16331..>16737
                     /locus_tag="VWX64_001595"
     CDS             16331..>16737
                     /locus_tag="VWX64_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEU9191037.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIRLIHCHGYSTNYFLYMLKKLDKNGFGKVKT"
BASE COUNT         5145 a         3070 c         3682 g         4840 t
ORIGIN      
        1 tataatggat atcaatcatc tcgtttttaa taagacggaa tttcttttca atcaaaataa
       61 atgggaaaaa gaagattcgt ttgaaagtga tttgacaaat acgttaaagg ataaaataca
      121 aaaatcagat ctcagttatt ctgacttaat gtctcttctt ctctatgatg cgatgaacca
      181 atccaccttt ttaacggata gtgaactttt tgaggatatt ttgaaaaaaa tcgaagattc
      241 tcataacacc cttctgtgta caggtcttgt cgagttactg ctgtatgaaa tgtctattag
      301 taacaataac aactggtcca acaaggttga taaaattagg atacacctca tcagaatcaa
      361 tcaattagat tttttctatt atacaagttg gttaaggcaa aattttgatt tctgtatgaa
      421 tagagagtat cataaaatga aatctcggaa attattactg agtaataaaa agatagttta
      481 agttcgtcct atttgtaaaa caaatgaaac aatttcaact aaggaggaga aaacaaatgg
      541 aacttgtatt accaaataat tatgttgtga ttgatgaaga agaaatgatg tatcttgatg
      601 ggggagctta tttaagcaag cgtgcttgtc aaggaatttg cgcagcttta gctatgagtc
      661 caggaacttt tatagcatta gctggagctg cagttttaac caaaaaacta ataaactata
      721 ttaaagttgg aggccttgga ggttggctta ttggtgcagc agcaggtgta ttggctgggg
      781 cggcaggaag aatagcttac tgtattggat atggtgctct taatagaggt tgtgatatta
      841 gcgggaaccc ttatccttgg gatggattta tatctgcgac agtaagatga ataatgtaga
      901 taagattcga aaaatacata ttatcgtatg ttggatgtat atatttttat cattcagggc
      961 gattataaat gacacggagt attttttgct tattttttta gcttttatct actcaatagt
     1021 atcactacct ctatattctg tgaaaaataa aatagtatct atctgtctag ccataaattc
     1081 gattctgtta atcagtttcc ccattttaat caataagttt ttcccagaaa gttttttgac
     1141 ttataccgta ttaataagtg tttttattac agagttgata atttttcatt taattgggaa
     1201 agattttgat actaaattga ctaacgaata taagaaaatt agtcagttta gaagcaaggt
     1261 gtctcaatct ccttggataa aatatttaga gatttctagt tttatattaa ctatatttcc
     1321 atctattctt tatggtacag ttgataatca tgtactgact cttatctttt tgataaaaat
     1381 ttgtgtagat actacgataa aatttttatt catcagatta tttgacacaa gtactttaat
     1441 gaagaggaga atattttttc ttttcgcatt ggatgttata gcttacttat ttttaggata
     1501 tcttttagtg attcaaaaag caggatatct gttttcgatt ttacttcttt tctctaattt
     1561 ttcagttcca tttatcaaag aaaaggaata cgaattattt aaaaatagca agtaatagaa
     1621 acataggtta aatcttagaa cggcttaaaa tcagatatga taaagggaaa tagtcttatc
     1681 taggtaacta agtgctacaa acacaatcga ggatcacttg ttaggattac attttaatca
     1741 tgcttaataa gaatggagaa ttcctatggg gattgtatta ctctgaagtt tcgaatacct
     1801 tagttctcgt gattttgagc tattctaggt ttagaatcct tcagaatgta aaattttaag
     1861 cagtcaaaga cttagaatag cctgaaaaca tttattttat aacaattcta ggcttagaat
     1921 tgctcatata tatgtatttg agctgctcga tagttaggac agctctattc tgagaaatct
     1981 gagctatcaa tgcttcagaa tagtatttcg ccaatggttt ttattgaaga ggtgattgtg
     2041 ttatgatagt ctaaaataaa attgatttaa tagagtaaat ggagaatcgt tacatgaaac
     2101 atttttttgc aggaattggt gagataaaac ttgttggcta cttattgtat atatgtgtag
     2161 gactagcccc tctttttcat atatatgtca taggttcgga actgagtttt gtgaaaatag
     2221 tgttatctat tttgggagtt atatttgtaa gtatgttaac tattgctcga atttatcgga
     2281 cttttctata aagaatagtt tggacttaaa ctgtatctaa aaacagaggt tggtagatta
     2341 tcagcctctt tcttgtcgtt gaaaagagtg agatatattg acttttgaaa aaaatgtcat
     2401 aattgagttg ggataaacct aaaagtaata tagtagattg aatctggaat agtccgttat
     2461 gactgttaaa atatttctag aaattaattt gactttccta atcgatttgt tcacatcttg
     2521 tttcaatcta ctatactttc tcgttaaacc gttcggtaat tcatggtgac atggacacat
     2581 agtagtaagc acactatgtg gcttggcaga tctaaaaact gttcccttgc gataagccta
     2641 ataagcacaa catagggagt tagagaagcc gactctaatc aaccactttg ggcagtagtg
     2701 gtaactgccc cgtgcttttt attttgagaa aatatggagt ttgtcgttga aattacttga
     2761 ttgtattttg gattatcaag aaagattcaa tggaaaaaca tgtcaagtat caacgaatta
     2821 taagtattta gagattttca aagtgaattt ttgcttgact gatttacatc atttatttga
     2881 cttacacaaa atcacacgag attatgctag tcaaacaaaa cctgctattc aagatggtgt
     2941 ttttatttta gaagatttta gaaatatcct atgtacaatg atgtaatcga aaggatatct
     3001 ttatatgagt ttatcggtga tattttctat tctaaaataa caagttgttg catcgtagct
     3061 agcgatttat ctaaaaatac tatgaaattg gacgtcatat tttttgagga taaaaataaa
     3121 agatccgcag ttttaggttt acgaagagac aaaagcggag tatttaaacc agttactcta
     3181 cattttacaa gcgctaagaa atatgctaaa gttcgtaaaa cagatgtgaa agaaatgaaa
     3241 tggctataaa gattgtccgc aggcttaagc ttgcgttttt tgttgtttaa cgaaattaaa
     3301 aaacaagctc tctcatcgga aatgttttta taggaatgaa ggaagatgat gctatgttta
     3361 aaaagagaat cgaaaagggc aaaagtagtg tctttatctt tttggagtag aagcttatga
     3421 tatagaaatt tgtaataaaa atgtaatata aaacatttga caaatattta cggggggagt
     3481 atacttaata taagtatagt ctaaaaatga ctatcagaaa agaggtaaat ttagatgaat
     3541 aagaaaaaaa tgattttaac aagtctagcc agcgtcgcta tcttaggggc tggttttgtt
     3601 acgtctcagc ctacttttgt aagagcagaa gaagctcccg tagctagtca gtctaaagct
     3661 gagaaagact atgatgcagc aatgaaaaat gctgaggatg cgaaaaaagc agtagaagat
     3721 gctcaaaagg ctttagatga cgcaaaagct gctcagaaaa agtatgccga ggatcagaag
     3781 aaaactgagg agaaagccgc gctagaaaaa gcagcgtctg aagagatgga taaggcagtg
     3841 gcagcagttc aacaagctac agacaaagcc gcaaaagacg cagcagataa gatgatagat
     3901 gaagctaaga aacgcgaaga agaggcaaaa actaaattta atactgttcg agcaatggta
     3961 gttcctgagc cagagcagtt ggctgagact aagaaaaaat cagaagaagc taaacaaaaa
     4021 gcaccagaac ttactaaaaa actagaagaa gctaaagcaa aattagaaga agctgagaaa
     4081 aaagctactg aagccaaaca aaaagtggat gcagaacatg ctgaagaagt cgttcctcaa
     4141 gctaaaatcg ctgagttgga aaatgaagtt cagaaactag aaaaagatct caaagagatt
     4201 gatgaatctg actcagaaga ttatgttaaa gaaggtctcc gtgctcctct tcaatctgaa
     4261 ttggatgcca aacaagctaa actatcaaaa cttgaagagt tgagtgataa gattgatgag
     4321 ttagacgctg aaattgcaaa acttgaaaaa aatgtagaag atttcaaaaa ctcaaacggt
     4381 gagcaagctg aacaataccg tgctgcagct gaagaagact tagctgctaa acaagctgaa
     4441 ttagaaaaaa ctgaagctga ccttaagaaa gcagttaatg agccagaaaa accagctcca
     4501 gctccagaaa ctccagcccc agaagcacca gctgaacaac caaaaccagc gccggctcct
     4561 caaccagctc ccgcaccaaa accagagaag ccagctgaac aaccaaaacc agaaaaaaca
     4621 gatgatcaac aagctgaaga agactatgct cgtagatcag aagaagaata taatcgcttg
     4681 actcaacagc aaccgccaaa agcagaaaaa ccagctcctg caccacaacc agagcaacca
     4741 gctcctgcac caaaaacagg ctggaaacaa gaaaacggta tgtggtactt ctacaatact
     4801 gatggttcaa tggcgacagg atggctccaa aacaacggat catggtacta cctcaacagc
     4861 aatggtgcta tggcaacagg ttggctccaa aacaatggat catggtatta cctaaatgct
     4921 aacggtgcta tggcaacagg atggctccaa aacaatggat catggtacta cctcaacagc
     4981 aatggcgcta tggcgacagg atggctccaa tacaatggct catggtacta tctaaacgct
     5041 agcggcgcta tggcaacagg ttgggctaaa gtcaacggat catggtacta cctcaacgct
     5101 aacggttcaa tggcaacagg ttggctccaa tacaacggat catggaacta cctcaacgct
     5161 aacggtgcta tggcaacagg ttgggctaaa gtcaacggat catggtacta cctcaacgct
     5221 aacggttcaa tggcaacagg ttgggtgaaa gatggagata cctggtacta tcttgaagca
     5281 tcaggtgcta tgaaagcaag ccaatggttc aaagtatcag ataaatggta ctatgtcaat
     5341 ggcttaggtg cccttgcagt caacacaact gtagatggct atgaagtcaa tgccaatggt
     5401 gaatgggttt aagccgatta aattaaatca tgttaagaac atttgacatt ttaattttga
     5461 aacaaagata aggttcgatt gaatagattt atgttcgtat tctttaggta cctatcttat
     5521 gatttcagga aatgtcatta aaaaaacgac tccttttctc taacttgaaa aatagattag
     5581 agaaaatggg ttgttttatt tattatagtt atttgaatga agataagaag aaggtatact
     5641 cacatcattc acataatctg tatgttgact ataagtttta aaaaacaatt tttaagctct
     5701 tccttgtctt ctccaaccaa gcgtgttata atgaatactg ctcaagcgac cttcaatcgt
     5761 gaagcacaca cgaccttcaa tcgtgaataa acgaatagat gggagactta ccatgagtga
     5821 taactctaaa acacgtgttg tcgtggggat gagtggtggt gttgattcgt cggtgacggc
     5881 tcttttgctt aaggagcagg gctacgatgt gatcggtatc ttcatgaaga actgggatga
     5941 cacagatgaa aacggcgtct gtacggcgac cgaagattac aaggatgtgg ttgcggtggc
     6001 agaccagatt ggcattccct actactctgt caattttgaa aaagagtact gggaccgcgt
     6061 ttttgagtat ttcctagcgg aataccgtgc agggcgcacg ccaaatccgg acgttatgtg
     6121 caacaaggaa atcaagttca aggccttttt ggactatgcc atgaccttgg gggcagacta
     6181 tgtagcgact gggcactatg ctcgagtggc gcgtgatgaa gatggcactg ttcacatgct
     6241 tcgtggcgtg gacaatggca aggaccagac ctatttcctc agccaacttt cgcaagaaca
     6301 actccaaaaa accatgttcc ctctgggaca tttggaaaag cctgaagtac gcagactagc
     6361 agaagaagca ggcctttcga ctgctaagaa gaaagactcg acagggattt gctttatcgg
     6421 agaaaaaaac tttaaaaact ttctcagcaa ctacctgcca gctcagcctg gtcgtatgat
     6481 gactgtggat ggtcgcgata tgggcgagca tgcaggtctt atgtactata caatcggtca
     6541 gcgtggcgga ctcggtatcg gtgggcaaca cggtggttac aatgcccctt ggttcgttgt
     6601 cggaaaagat ctaagcaaga atattctcta tgtaggacaa ggattctacc atgactcgct
     6661 catgtcaact agcctagaag ccagtcaagt ccactttact cgtgaaatgc cagaagagtt
     6721 tgcgctagaa tgtacggcta aattccgtta ccgtcagcct gactctaagg tgaccgtcca
     6781 tgtcaaagga gacaaggcag aagttatctt tgcagaacca caacgcgcga ttacaccagg
     6841 acaggcagtt gtcttttacg atggcgaaga gtgtctaggt ggcggtttga ttgacaatgc
     6901 ttaccgcgat ggacaagttt gtcagtacat ttagattgac aaattttctc aatttgctac
     6961 aataataaca gcaatagaaa tgatggtcaa agctcatgga tgttgcaggc ttttttgtcc
     7021 tgcacttctt tgtagttttg actgtttttg tgtcgtttaa gggaaaggac aagaatgact
     7081 caacaagact ttcggacaaa agtagacaat acggtttttg gtgttcgggc tacagccttg
     7141 attgtccaaa atcacaagct tctagttacc aaagacaagg gcaagtatta cactattgga
     7201 ggtgcgattc aagtcaatga aagcacggaa gacgcggtag tccgtgaagt gaaggaagaa
     7261 ctgggtgtca aagctcaagc tgggcagcta gcttttgtgg ttgaaaatcg ttttgaacaa
     7321 gacggcgttt cctatcacaa tatcgaattt cattatctgg tggatttgct tgaagatgcc
     7381 ccgttgacca tgcaggaaga tgagaaaagg cagccctgtg agtggattga cttggataag
     7441 cttgaggata tccagctagt tccagccttt ttaaaaacgg ccctaccagg ttgggaaggc
     7501 caactaagac acattcatct tgaagaatag gagagaaaca tgacttatca ttttactgaa
     7561 gaatacgata ttattgtaat tggtgcggga cacgctgggg ttgaggcttc cttggccgct
     7621 agccgtatgg gctgtaaggt cctgcttgcg actattaaca ttgaaatgct ggctttcatg
     7681 ccttgtaatc cctctatcgg tggttctgct aaggggattg tcgtacgtga agtcgatgcc
     7741 ctcggtggcg agatggccaa gaccattgac aagacttaca tccagatgaa gatgctcaac
     7801 acagggaagg ggccagctgt ccgtgctctt cgtgcgcagg ctgacaagga actttactct
     7861 aaggagatgc gaaagacagt tgaaaatcaa gaaaatctga cccttcgtca aaccatgatt
     7921 gatgagattt tggtggaaga tggcaaggtt gtcggtgtgc gtacagccac ccatcaagaa
     7981 tatgctgcta aggctgttat tgtgacgaca gggactgctc tccgtgggga aattatcatc
     8041 ggagacctca agtactcatc aggtcctaac cacagcttgg cttctattaa cctagctgac
     8101 aatctcaagg aactgggcct cgaaatcggt cgtttcaaga caggaacccc tccacgtgtc
     8161 aaggcttctt ctatcaacta cgacgtgaca gaaatccaac caggagatga agcgcctaat
     8221 cacttctcat acacttcacg tgatgaggat tatgtcaagg accaagtgcc atgctggttg
     8281 acctatacca atggtaccag tcatgagatt atccaaaaca acctccaccg tgcgcctatg
     8341 tttacaggtg tggtcaaggg agtggggcct cgttactgtc cgtcgattga agacaagatt
     8401 gtgcgctttg cggacaagga acgtcaccaa ctcttccttg agccagaagg gcgcaatact
     8461 gaggaagtct atgttcaagg actttcaacc agtctgcctg aggatgtcca gcgtgacttg
     8521 gttcattcca tcaaaggttt ggaaaatgca gagatgatgc ggacaggtta tgctattgag
     8581 tatgatatgg tcttgcctca tcagttgcgt gcgactttgg aaaccaagaa aatctcaggt
     8641 ctcttcactg ctggtcagac aaatggaacg tcaggttacg aagaggcagc aggccaaggg
     8701 attatcgcag gtatcaatgc ggctctaaaa atccaaggca aacctgagtt gattttgaag
     8761 cgcagtgatg gttatatagg ggtgatgatt gatgacttag tgaccaaggg aaccattgaa
     8821 ccttaccgtc tcttgactag tcgtgctgaa taccgtctca ttcttcgcca tgacaatgcc
     8881 gatatgcgtt tgacagagat gggccgtgag attggccttg tggatgatga acgctgggct
     8941 cgttttgaaa tcaagaaaaa tcaatttgat aatgagatga aacgcctaga cagtatcaaa
     9001 ctcaagccag tcaaggaaac caatgctaag gttgaggaaa tgggcttcaa acccttgacc
     9061 gatgcggtga cagccaagga attccttcgc cgtccagaag tttcttacca agatgtggtg
     9121 gccttcatcg gaccagctgc agaagacttg gatgacaaga ttatcgaatt gattgaaaca
     9181 gaaatcaagt atgaaggcta tatttccaaa gccatggacc aggttgccaa gatgaaacgt
     9241 atggaagaaa aacgcattcc agccaatatt gactgggatg acatcgattc tattgcgacg
     9301 gaagctcgtc agaagttcaa actcatcaat ccagaaacca tcggccaagc cagccgtatt
     9361 tcgggagtaa acccagcaga tatttctatt ttgatggtgt atctggaagg taaaaatcgt
     9421 agtatttcta aaactcttca aaaatcaaaa tgatacgtcg tcggcttctt acgaatgagt
     9481 tcaaagcttg gctttgattc atctccagcc tcccatagtt ccccgaacta tgggagctaa
     9541 ctcaagttat gctttcgctt agccttctag tctgatttcg atttttattg atactcttcg
     9601 aaaatctctt caaaccgcgt caacgtcgcc ttgccgtata tatgttactg acttcgtcag
     9661 ttctatctac aacctcaaag cagtgctttg agcagcctac ggctagtttc ctagtttgct
     9721 ctctgatttt cattgagtat gagttttaat ctcaaaagaa agcatagaga aaaacagctc
     9781 cgaggacggg gctgttttct tgctttattc ttcatctggt gtgaggatca tcgggatgat
     9841 gatcggttca cgttcggtat tttcatagag gaaggggcga atagcgttga caatggcacc
     9901 attgacagat tgcacgctag catccttatt tttcagtgcg atacgaatgg cattgaagag
     9961 gatacgctgg ctttggcgaa tcaagtcgcc agactctctc atgtagacaa agcctcggct
    10021 gaggatgtct ggaccagata gaatcatctg cgatttgaag tcaacagttg cgactgccag
    10081 aacgacaccg tcttcagata gatcgcgacg atctttgagg acagctgcgc caatttcacc
    10141 gatacgattt ccatcgacat agatatcttg ggcgttgaaa tgacctgcga tacgagctga
    10201 gtcagcagta agggcaagca catcgccatt gctcatgata aagatattgt ccttctcaac
    10261 accagtatcc actgctagtc cagcgtggac tttttgcatg cggtattcac cgtggacagg
    10321 catgaagtat tttggcttaa tcaagcagag catgagtttt tgctcttgct gaccaccgtg
    10381 tccagatgta tggatattgt tcactttacc gtggataact tcgacaccag cttcagaaat
    10441 gatgttaatc agcttgttga cgctagtagt gtttccaggg atgggactag aagagaagat
    10501 aacggtatca cctggttgta attgtacttg acggtgggtt ccgttggcga tacgagagag
    10561 ggctgccata ggctcaccct gactacctgt acagaggata agaacttctc ctgcaggata
    10621 atctttgatt tcatttggct cgataaaggt tcccttagga gctttgatgt agccaagatc
    10681 gattccgttg acaatggcct tttccataga acgaccaaag accgcaatct tgcgtccagt
    10741 cttaacagca gcttctgttg cctgctggag acggaagata tttgaggcaa aggatgcaaa
    10801 gatgatacgt ccttcaatac cttggataat cttcataatg gactgaccaa cgactttttc
    10861 agagttggta aaggttggta cttccgcatt tgtcgagtca gacaggagac agagcacgcc
    10921 ttcttcacca agcgcagcca tacgatgcaa gtccgcaggt tctccaactg gagtaaagtc
    10981 gaacttaaag tcacccgtac agacgatttt cccttgagga gtatgaatga caatccccaa
    11041 aggctctgga atagagtgag tcgttctaaa gaaagttgcc ttgagatttt taaaggtcaa
    11101 ctcggtgttg tggttgattt cgtaaagttt ggcgttgcgc aagaggccgt gttcttcgag
    11161 tttcccacgg atcaaagcca aggcaagcgg tccagcgtag atagggacat ttgcttgctt
    11221 gagtaggaac ggaatcccac caatgtggtc ctcgtgtccg tgtgtgatta aaacagcctt
    11281 gacgcggtcg atattgtcca cgatgtaaga gtagtcagga atgacatagt cgataccaag
    11341 caagtcatct tctgggaatt taatcccagc atcgacgatg ataatctcgt cttggtattc
    11401 aattccgtaa gtgtttttcc cgatttctcc tagaccaccg atggcaaaaa cgccgacttc
    11461 ttcaggttta agagtgtagg ccatattaga actccgtaat ttcgaaggcg ccagtttctt
    11521 tttcgtaatc gagcaatttg tcagacaaga gttcgatata ctcgatattg tactctgggc
    11581 gattttcttc gacaagttgg cgagcagtga tacggccctc aagttctgag ctggcatcga
    11641 tgtctaggta aagcgtgcgt gttgtttcac ggcgtgggct acgttctttt gtttcttgat
    11701 aaaaaacttt gtaaatcata tagttccttt ctatttacag gtcagcttat tccaaacttt
    11761 tagcagatat ttgcttgatt tcattccatt ttgtgtctag attgaccttg attcgttaca
    11821 attatttcaa ttataccaca aaatgaaaaa ttagtaaaag acggaaacga gaaagttagg
    11881 ggacgatttc tttggtaagc gtttgcaaga ataaagaaaa tgtattatgt tgataacgga
    11941 agtgaaattt attgcttgtc ataattccat atagatttta agtcaaggag gttgccctat
    12001 gtataactta tttgcttttg ctatcggagc tcgcttggta gcttttattg tttttgttgc
    12061 ttgcgtttat gcggggaatc ttctatttgc caaactggaa cgacgacaaa ccaagttctt
    12121 gtggaaaatg acctttgtga ctctctactc gctttttctc ctcctcgtga cctatgtcgt
    12181 ttggtttgta ttttactttg aattaaatgc ttagatgccc tgcttatgct ggggtttttt
    12241 gtttggggat gtagagatag tagatttacg acacgaaaat tccaccccat ctatcaagat
    12301 gaggtggtct ttgcattttt ctaacatgac atgacaatgg aattttcaaa gcttattatt
    12361 tttatgggag tcattgttct gatcaaaaat agagttgaag cataaaaata aaacaataca
    12421 aacagataaa tcgaatggta aagggatggt agtaatgttc aaatcattga gaatgctgag
    12481 caaactgtaa gagatgaaga caataaaatt tatccttcta aaaatgtgtt tcttatctag
    12541 catgacttac caaacttttt acgaaggtct tttccaatgg tataacctgc cataaataaa
    12601 gcgataccaa caccgacacc aaagccaccc ttgatttctt gcaattcctt attagaaatt
    12661 tcacgataat tgttcaaatc tttcatcata ttaatctcct cctaaaaaat aaccagctgc
    12721 caaaccagaa cctataagtg ctgttccacc tgcaatagcc ttccaagata ctgctactcc
    12781 aaagataacc aagggagcga gaccgccatc aatatctgat aattcatttt cagataagga
    12841 taaaaattga ttgtcaagaa tgtcaaaatt tgtcattgaa ctttcctcct tttttcttgt
    12901 tcacttttat attcggaaaa gaaaaggaaa agtgagcatt tttttaaatt atttttagtt
    12961 aagtgagggc actcttgtct gggggcaaag aaaattccca tgtgccagct tttgtagtat
    13021 aatagtaagc agacaaaaag ataggaatgt gttatgaaag tattagcttt tgatacgtcc
    13081 agcaaggctc tttctctggc tattttagag gataagcagg ttcttgccga gacgacgatt
    13141 aatattaaga aaaatcacag tattactctt atgcctgcca tcgatttttt gatggcaagt
    13201 ttggattgga cacccaagga tttggaccga atcgtggtag ctgaagggcc gggtagctat
    13261 acaggcttgc gaattgcggt agcaactgct aagaccttag cttacaccct gaacatcgag
    13321 ttggttggta tgtcgagtct cttggctctg gtgccccacc aacaagaagg tttgtttgtc
    13381 cccttgatgg atgcgcgtcg caataatgtt tatgcaggat tttatgaaaa tgccaaacct
    13441 gtcatggcag aagcgcacct atcttttgaa gaggtgctag aaaaagtcaa gggtactagt
    13501 caggtaacct ttgtcggaga agttggcccc tttgttgagc agattcaaaa acacttgcca
    13561 aggactgatt acaaagaaac attgcccaat gcagctaatc tagctctttt ggcctgggac
    13621 aaggaagcag actccttgca tgattttgtg ccgaattacc tcaaacgagt cgaggctgag
    13681 gaaaactggc tcaagaacca taccgagtct ggcgagtctt acattaaacg cctatgatag
    13741 aaatcaagcg aattcaacaa cagcctgacc tagctcaagc catctacgct gttatggcag
    13801 ctgtttacct agtcagtcct tggactctgg agcaaatcca agcagatctg tcccaagacc
    13861 agacttggta tgcattggct tatgatgggg cagaagtgat tggatttcta gctgtgcagg
    13921 agaatctttt tgaagcagaa gtcctgcaaa tcgctgtcaa aggagcttat cagggtcagg
    13981 gaattgcgtc agccttgttt gctcaattgc cgacagacaa ggaaattttc ctcgaagtca
    14041 gacagtcaaa tcaacgagcg caagcatttt acaagaaaga aaagatggca gttatcgctg
    14101 agcgaaaggc ctactaccat gacccagtcg aggacgccat tatcatgaag agagaaatag
    14161 atgaaggata gatatatttt agcatttgag acatcctgtg atgagaccag tgtcgccgtc
    14221 ttgaaaaacg acgatgagct cttgtccaat gtcattgcta gtcaaattga gagtcacaaa
    14281 cgttttggtg gcgtagtgcc cgaagtagcc agtcgtcacc atgtcgaggt cattacagcc
    14341 tgtatcgagg aggcattggc agaagcaggg attaccgaag aggacgtgac agctgttgcg
    14401 gttacctatg gaccgggctt agtcggagcc ttgctagttg gcttgtcagc tgccaagacc
    14461 tttgcttggg ctcacggact tccgctgatc cctgttaatc acatggctgg gcacctcatg
    14521 gccgctcaga gtgtggagcc tttggagttt cctttgttgg cactcttggt cagcggtggc
    14581 cacacagagt tggtctatgt ttcggaggca ggagattata agattgttgg ggagacacga
    14641 gacgatgcag ttggggaggc ttatgacaag gtcggccgtg tcatgggctt gacctatcct
    14701 gcaggtcgtg agattgacga gctggctcat caggggcagg atatttatga tttcccccgt
    14761 gccatgatta aggaagataa tctggagttc tccttctcag gtttgaaatc tgcctttatc
    14821 aatctttatc acaatgccga gcaaaaggga gaaagcctgt ctacagaaga tttgtgtgct
    14881 tccttccaag cagcagttat ggacattctc atggcaaaaa ccaagaaggc tttggagaaa
    14941 tatcctgtta aaaccctggt tgtggcaggt ggtgtggcag ccaataaagg tctcagagaa
    15001 cgcctagcag ccgaaatcac agatgtcaag gttatcatcc cccctctgcg actctgcgga
    15061 gacaatgcag gtatgattgc ctatgccagc gtcagcgagt ggaacaaaga aaacttcgca
    15121 ggctgggacc tcaatgccaa accaagtctt gcctttgata ccatggaata aagcattcca
    15181 aagtcttgtc tgactctgga atgttttctg ttcacagttg ttttgtaact gcctaataag
    15241 taaccgccta ataagtaacc gcgctataac gaggtatcta ccgagattgt caattctcca
    15301 gtatactgtt ataaaaaaca aaactggagg atttttttat gtccccccat cgtcccatcg
    15361 actgttccgt agctgcccaa taacggagta tagtcggctg aaacaagaat aggacaaaag
    15421 tgcctcaaga aaagcatcgt aatttgacaa tattattctg agatgttttt gatgtaagcc
    15481 catattttct caatgggatt atactcgggt gaataggtag gaagtggtaa cagtctatgc
    15541 cctgctcctt acacatgttc attctgtgaa accttgcatg gtccataatg ataagggatg
    15601 gtgtatctaa agtaggtagt aagaattttt ggaagcaagc ttcgaaaaag tcactcgtca
    15661 tcgtatcttt ataggtcatc ggagccatag tatattgaaa caaaaaaggg cattagtact
    15721 tctataacag tatcgcaatc tctggtgtgc gttgtctcga tcttaattca aataattata
    15781 tcttcttcca gagagactaa ctgcctgctc aaggctcgat catattcgag ataaaaatag
    15841 gtctcaaccc ctgtctcata aatataaata ggagtcaggt agcttaagtg attcaattct
    15901 ttaaggaacc gatttacttt ttctgggtct tgttcgcagt aggtacggct cttttttaga
    15961 ctatatccca tagcctttag agcgtaatga atagttgttg gaggacagtt gaattcagca
    16021 gctatttcag tcaaataagc atcgggatga gtttcaatat agatctttaa tttatctcta
    16081 tcaacttttt caattaatag tggaagtttt cttaaagtta gtgtgttgaa acgtttttat
    16141 acagtgctaa aatttgaagt gtagtgcaga tgtatttgta atagtattat agcaattctt
    16201 tggagaaggt cgagacaaga gaaaataggt atctttgaga tataagcatg atttactata
    16261 aaattattga gttattcata aaaatttctc tatcaaatat cataatgcgt cgtttaagga
    16321 gatggttaca atgcaatata gttgtggaaa aataaatatt aatatccctg atggatatgg
    16381 agacattaag gatatagtgt tttcggctca tattatagtt aggtataata atggacattg
    16441 tggaggtata gatccgcata taattggact ttgtaaaaag cagatcagaa ggatgtctct
    16501 atatcctatt ttgataatcg tatctagaga ttcaaaggtt attgatgatt ataaaaattt
    16561 agatattgcc tatgttgatt gtactcaatg ttcaaataat tttgaaactg ccttacacgt
    16621 taaaaatatt ttaaaattat taaaaatccg acttatacac tgtcatggct actcaactaa
    16681 ttatttttta tatatgttaa aaaaacttga caagaatgga tttggaaagg ttaagac
//
LOCUS       DAVKBC010000040        15472 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVKBC010000040 DAVKBC010000000
VERSION     DAVKBC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.040"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..1116
                     /locus_tag="VWX64_001596"
                     /pseudo
     CDS             1..1116
                     /locus_tag="VWX64_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1201..2403)
                     /gene="rpsA"
                     /locus_tag="VWX64_001597"
     CDS             complement(1201..2403)
                     /gene="rpsA"
                     /locus_tag="VWX64_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU9191038.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(2565..2636)
                     /locus_tag="VWX64_001598"
     tRNA            complement(2565..2636)
                     /locus_tag="VWX64_001598"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2602..2604),aa:Gln,seq:ttg)
     gene            complement(2646..2726)
                     /locus_tag="VWX64_001599"
     tRNA            complement(2646..2726)
                     /locus_tag="VWX64_001599"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2690..2692),aa:Tyr,seq:gta)
     gene            complement(2776..3006)
                     /locus_tag="VWX64_001600"
     CDS             complement(2776..3006)
                     /locus_tag="VWX64_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU9191039.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(3174..3818)
                     /gene="pcp"
                     /locus_tag="VWX64_001601"
     CDS             complement(3174..3818)
                     /gene="pcp"
                     /locus_tag="VWX64_001601"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU9191040.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(3833..4756)
                     /locus_tag="VWX64_001602"
     CDS             complement(3833..4756)
                     /locus_tag="VWX64_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU9191041.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(4753..5442)
                     /locus_tag="VWX64_001603"
     CDS             complement(4753..5442)
                     /locus_tag="VWX64_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU9191042.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(5507..6211)
                     /locus_tag="VWX64_001604"
     CDS             complement(5507..6211)
                     /locus_tag="VWX64_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9191043.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(6267..7289)
                     /locus_tag="VWX64_001605"
     CDS             complement(6267..7289)
                     /locus_tag="VWX64_001605"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU9191044.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEYATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(7419..9890)
                     /gene="parC"
                     /locus_tag="VWX64_001606"
     CDS             complement(7419..9890)
                     /gene="parC"
                     /locus_tag="VWX64_001606"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU9191045.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLV
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(10310..12253)
                     /gene="parE"
                     /locus_tag="VWX64_001607"
     CDS             complement(10310..12253)
                     /gene="parE"
                     /locus_tag="VWX64_001607"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU9191046.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            12389..13030
                     /gene="plsY"
                     /locus_tag="VWX64_001608"
     CDS             12389..13030
                     /gene="plsY"
                     /locus_tag="VWX64_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU9191047.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(13111..14340)
                     /locus_tag="VWX64_001609"
     CDS             complement(13111..14340)
                     /locus_tag="VWX64_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9191048.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLRYDRVVRCRVKIITMDMFSPYYG
                     LAKQLRFHIVQHLSRAMSRVRVQIMNQFHRKFHEYKAIKRYWKLIQQDSRKLSDKRFY
                     RPTFRIHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVH
                     PIFQTVFKTFLKDKEKIVNALQLHYSNAKLESTNNLIKLIKRNAFGFRNFENFKKRIF
                     IALNIKKERTKFVLSRA"
     gene            complement(14469..15472)
                     /locus_tag="VWX64_001610"
                     /pseudo
     CDS             complement(14469..15472)
                     /locus_tag="VWX64_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4457 a         3390 c         2763 g         4862 t
ORIGIN      
        1 ctagaattct ccttagaaaa cgccgtttca agtgctatca ctgttcaaaa atgatggttg
       61 ctgagactcc cctggtaaag aaaaatcacc aaatccctcg tatcatcaac caaaaaattg
      121 ctcaaaagtt aattgaaaag atttctatga ctgatattgc ccatcagctt tccatctcaa
      181 cttcaactgt cattcgcaag ctcaatgatt ctcactttga gcatgatttt tcgcgtcttc
      241 ctgagattat gtcctgggac gttgaaacag tccggggagt gactgtttca atcgggagat
      301 ggagatgagc ttcattgcgc aagattttaa caatctcaat atcatcactg ttcttgaggg
      361 aagaacacaa gctatcattc gaaatcactt tcttcgctac gatagagctg tccgatgtcg
      421 cgtcaaaatt attactatgg atatgtttag cccttactat gacttggcta aacagcttcg
      481 ctttcaaatt tctaggctca ggctgaaaca gtctcccagg ctgtttcact cccgaatgct
      541 aaaatcgttc ttgatcgctt tcacattgta caacatctta gccgtgctat gagtcgtgtg
      601 cgtgttcaaa tcatgaatca gtttcatcga aaattccatg aatacaaggc tatcaagcgc
      661 tactggaagc tcatacaaca ggatagccgt aaactgagtg ataagcgatt ttatcgtcct
      721 acttttcgta tgcacttaac caataaagag attttaaaca agcttttgag ctattcggaa
      781 gacttgaaac accactatca gctctatcaa ctcttgcttt ttcacttcca gaataaggaa
      841 ccagagaaat ttttcggact tattgaggac aatcttaagc aggttcatcc tatttttcag
      901 actgtcttta aaaccttcct caaagataaa gaaaagatta tcaacgccct tcaactacac
      961 tattctaacg ccaaactgga agcgaccaat aatctcatca aacttatcaa gcgcaatgcc
     1021 tttggttttc ggaactttga aaacttcaaa aaacggattt ttatcgctct gaatatcaaa
     1081 aaagaaagga tgaaatttgt cctttctcga gcttagctga cttcaaccca ctacagttga
     1141 caaagagcca gaaaaatccc ttgtttagta aacaaaggat tttgtgaatt ttcaatttga
     1201 ttaaagttcg atatcaccaa acaaatcagc cattgaaaat cctgtttgtg tttctggaag
     1261 ttcgaaatca cgcttttctt gacgtcttgg acgacgtgga cgagcagcac gtttttcttc
     1321 tttttgtcct tcttcttggg ctggacgttc ttcaagagct ttaatagaaa gtgacacgcg
     1381 ttctgcatct gcgttaactt caagaacttt aacttgaact tcttgaccaa ctttaagagc
     1441 ttcttttgga ttttcaatcc gtttgtgtga aatttgtgat acgtgaacaa gtccatcgat
     1501 acctggcaat acttcaacaa atgcaccgaa gtcagtcaaa cgtttaactg ttccttctac
     1561 tacatcacct ttagccaatt tttgctcaac gccatcccat ggtcctggta ctgttgcttt
     1621 aagtgaaagt gatacacgtc cttcttcttc gttaagatca aggattttca cttcaatttc
     1681 ttcaccaaca gttacaactg attttggtga tacgttacgt tcatgtgaca attcagtcaa
     1741 gtgaaccaat ccgtcaacac caccaaggtc gatgaaagcg ccgaagcttg tgatacgagc
     1801 aactttacca gttacaacat caccaacagc caatttaccg aatacttcag cgcgagctgc
     1861 tgcagtagct gcttcaacaa cttcacgacg tgaaaggatg aagcggtttt ctttagcgtt
     1921 aacttctttg attttagtat caaattcttg acctacaaaa cgctcagcgt tacgtacgaa
     1981 acgagtatcc aacattgaag ctgggataaa tccacgaaca ccttcaaatt ctactgaaag
     2041 tccaccttta acggcacgcg ttcctttaac agtaacaact tcttcttcgc gaccaacaag
     2101 tttgtcccat gctttgcgag cttcaaggcg ttttttagat acaaggtatg taactgtatc
     2161 agtatcttta ccaactactt gacgaagtac aagaacatcc aatacttctc ctactttaac
     2221 aaagtcattg atatctgcat cacgatcgtt tgtcaattcg cgaagagtca agacaccttc
     2281 aacaccagtt ccagagattg caacgttagc ttgagtcgca tcaactgtca atacttcagc
     2341 actaacaaca tcaccagtct caacttgact aacgctattt agcaaatctt caaattcgtt
     2401 catctaaaaa atcctccaac aatcaagttt ttcttaaact tgacatactt ataatttttt
     2461 tcctaagcac ccgcaaggac atgttcatat cattcacgtc tttcaattat aaaaataaaa
     2521 taccctaaga tattttgctt tctatcttga ttattaccta agaactgggg tagctggatt
     2581 cgaaccaacg catgagggag tcaaagtccc ttgccttacc gcttggctat accccattaa
     2641 tgaaatggag agagagggat tcgaaccccc gaacccgaag gagcggattt acagtccgcc
     2701 gcgtttagcc tcttcgctat ctctcctaca atcaacatgg actattatat catgaaaatt
     2761 tcaaaaaaac aagacttatt ttgctaaatt ataattttca atcaaaattt ccacagcttt
     2821 ttccaatttt ttataaaaac tatcgacatt cccattcttt ataatggcaa attgtccgtc
     2881 taattcggca atttctccga taactttttt accgatagtc aatgtataac cttcaaaact
     2941 gtctttacca acattaactt tggcatccgc tacttgaatt tcgatttttt tatctttctt
     3001 gctcatttca tacctctctt cactttttct attttacaag aaaatcctaa aactagcaag
     3061 aaaaaactct atatcaggct tctctgatat agagttttat gtaaacaacc tcaattgatt
     3121 tagcatagtt aatagttagt aaacaagcat aattgactat cctttttagg ttatcagtga
     3181 gtctcaccgc ctactaactg caaatcctta tctttgtagt ctacaatagc ttcaatagct
     3241 acctctatgc ctcttacaat atcacataga ctcattcctg cagtattcgg cttatttact
     3301 acttgttcca tcatatatgg aatatgcatg aaacctgctc tcatattagg gaatttttta
     3361 tccactaaat aaagagcttg gtacatcaaa tgattgcaaa caaaggttcc tgcactattg
     3421 gatacaactg ccggaagtcc ctgttttttg atagcttgta ccatcgcttt gataggtaaa
     3481 ctactaaaat aggccgatgc tccatcaata cgaatcggtg tatcaattgg ttgattgcct
     3541 tcgttatcag gtatgcgagc atcatcttga ttaatagcca ctcgttcagg tgttaagccg
     3601 gtcctgccgc ctgcttgtcc aatacaaagt acagcatctg gttgatatcg taatatttct
     3661 gcctctaaaa cttctgacga cttataaaaa accgttggaa tttctaccca gcgaacttca
     3721 gccccattaa tctcagatgg taataatttt acagcctcca aagctggatt aatcttttca
     3781 cctccaaaag gattaaaacc tgtaaccaat attttcattt tattttcctt tactaaaatg
     3841 cgagaaagta cattaagaat atgtgaataa caatcattac tagagcaaca cctgcttgag
     3901 cctttataac gccattctga tctttcatat ccatcaatgc tgctggtaga gcgttaaaat
     3961 tagcagccat tggggtcaat aaggtcccac aataacctgc tgtcatggca agagcaccag
     4021 ccacaattgg attagctccc agagcaaata caaagggaac tccaacacct gctgtaataa
     4081 cggtgaatgc tgcaaaagca tttcccataa tcattgtgaa tagaaccatt ccaagaacat
     4141 aagccaaaac tcctataaag cgactatctg aaggaacaat accgctaatc agatgagaga
     4201 taacatcacc aacacctgct acagtaaaaa tagcccccaa agcccctaat aattgaggaa
     4261 caatcccact tgttgaaact tgctgagtca ttcgattatt ttctgataac agactcttag
     4321 ggtgactatt ggtaatcaca agaacagaaa ttgtagcaaa caaggcggca aggctaatcg
     4381 aaatcttgct aaattctgga atcatttgcg ctaagaccaa cgcaagtatt gccatcagca
     4441 taactggaat aaaaatttta tttttcaatc tgttagattc aatattggct ttcatttcat
     4501 ctaaggatgg caaggttccg atacggactt gcttaaacaa tgttaacagc gataatagga
     4561 ttacaataat accaatactc atatttggca tataggaacc acctataaac gtaatagaca
     4621 atagagtcca aaatgcagat gtcccaagtc gaactgggtt tgttttatct ttataactac
     4681 aataggctgt atggagaaat tgacaaccaa tcacaatata ggtcaactct aatagttgct
     4741 ttgccaactc tgtcattttt gttctcctcc cctagtcttt tttgatatca attttttatc
     4801 aaataaataa ttgtaaatcc ccactacaat aagtgttata acagcaacaa taatagatgt
     4861 agaagcaatc cctgcataat tgctttcata gcctaactga tctaatgttc cccctatcaa
     4921 gaggactccc ccagcaccta caaacgtatt ttgagcaaag aaatttccaa aattttcatt
     4981 cgcagccgca cgcgctttta ttgtctcatc ttcaacctct gttaactttc tacctaattg
     5041 agactctgca gctgcttctc ccataggttg aaccaaaggt ctgacaaact gagggtgtcc
     5101 tcctagacga attgaaaaga aaccagctaa ctctcgaata aagaaataaa ctgtatagaa
     5161 gtttccaact gtcagacctt taatctttcg aatcaaatcg attgatcgtt gcttgagtcc
     5221 aaaggtttct gacagcccca caagaggcaa ggtaaccata aaaatcgtga gcactcgctg
     5281 attgctaaat tcttttccca aaatctccaa aaattcaacg agagaaacac ctgaaactaa
     5341 agctgtaacc aaaccagcta agactactgt tgcaattgta tcaaatttta aaataaaacc
     5401 cacaacaatg attgctattc ctattaatct aatccactcc atatcaaact cctttatatt
     5461 caaaatgaca gtattttaaa aattttatca agatcaatac cattccttat ttaatgtatt
     5521 tttctagttc tttttggtat ttgctattgg attccaattt ttctttttgc cattttttaa
     5581 aaacctcgtt atattctttt gttgtaacaa tatctttttg caatttcatt cctttaaaga
     5641 tatatggttc ccccttaata ccaacttgtg agtatggttt tgagaatggt actacgttac
     5701 ttacaactgg agaaccacca gatgaagctg ttggcatcaa taatgaacta tctgtcgacc
     5761 aagcttgagc tttggcatat ttttcatatc tcttctctag gtcagtggtc tcagaaacag
     5821 catcttctaa caatttctta tatttatcca aaccaggttt agctacaaca tccttatctt
     5881 ttcctttcgt aatgccaagg tgtttcatgg cagaaccaga ttttggatcc ataatattca
     5941 agtaagacgc tggatcttga tagcttggag cccatcctgt actgttcaaa tcatagtctt
     6001 tttgagaagg agcaacattg ccgtatttat cattttccat caaaccatca ataacatttc
     6061 caataacgtc tgtcctcgat gttcgagtcg ctatactgta gcccaatgat gctggatcta
     6121 ctgcatagac ataagaaaat gttgtcggtg catctgcttc tttatcagtt tttccacaag
     6181 ccactaaaat agctgacgtg ctcaggacca ctcctgctgt taagagccac tttttctatt
     6241 tcataaaaaa tctcctttgg tttattttaa tctactttta caatccaacc ttctggcgct
     6301 tcaatatcgc caaactgaat acccgtcaat tcattatata atttacgcgt cacaggacct
     6361 acttctgttt cactatagaa tacatggaaa tcatcaccat gttgaatacc tccaattgga
     6421 gaaataaccg ctgctgtacc acaggcacct gcctctacaa aacggtcaag attatcaatt
     6481 ggaacatcac cctcaatagg agttaatccc aagcgatgtt ctgccaaata aagcaaggaa
     6541 tacttggtaa tagatggcaa gatagatgga ctcaatggtg ttacaaattc attatcagct
     6601 gtaattccaa agaaattagc tgatccgact tcttcaatct ttgtatgagt tgatgggtcc
     6661 agatagataa catctgagaa atggcgtgac ttggccattt ttcctggtaa gagacttgca
     6721 gcatagtttc caccaacctt agccgcacct gtaccatttg gtgctgcacg gtcgtactca
     6781 tcctgaatca agaagttggt tgggaccaaa ccacctttaa agtaatttcc aactggcata
     6841 gcaaagatgg tgaaaatgta ctcttctgcc ggttttaccc cgataatatc tccgacacca
     6901 atcaaaagag ggcgaagata taaagttcca cctattccgt atggtggtac gtattcttca
     6961 ttcgcacgga caactgcttt acaagcttct acaaacatgt ctgtcggaac ttgtggcatc
     7021 aagagacggt cacatgtacg ttgcaggcgt ttagcatttt catcaggacg gaacagttga
     7081 acactgccat ccttagtacg ataagctttc aaaccttcaa atgcttgttg tccatagtga
     7141 agacttggag aagactctga aatatgcaaa gttgcatact ctgtaagctc tccttgatcc
     7201 cattgtccat ttttgaaatg agcaagatag cgataaggta atttcatata ggaaaaaccg
     7261 aggttttccc aatcaatcgt tactgtcata ttccactcct tattctaaaa acctatttct
     7321 tatattctac actatttttc taaaatagca agtatatttt gtaattttca gaaaatttct
     7381 ccaataaaaa ccatcttaga actgattctt catttcactt atttatcttc agtaactact
     7441 tcctgaagat aagcgtcaaa aacttcttca tctgaaatcg tgtcagaaat gaagcttcca
     7501 ttgctagtgc gttctgacaa gttcaagtct tgcaatcggc tttcatagat tgttccttta
     7561 ttggattgga caagcagagt ttggtcgttc acatccactt ccgtactgaa gaaatcgcca
     7621 acaaatcctt gctctgcaac tgctcctgcc aagaagacac gatgcggttt gtttttcaac
     7681 tcacgcaaga cttgtaatcc tcgtttggca cggctggttg ctagaatttc ctcaatggaa
     7741 acacgtttca agcttccacg ctgggtcaag aggtagaagg acgaagtatt acagataaag
     7801 ccagattgga ggacatcatc ttctttcaaa ttcatagcct tgacacctgc tgccttagca
     7861 ccgacaaccg gaacctcttc gatattgaaa cgcagggcat aaccattttg actaaccaag
     7921 acaacatcat ctagtttaat cggagccact gctacaatct gatctgtatc gtctttgagc
     7981 ttagcatact tgacagactt agatctatag gtccgccatg gagtgaattc ttttcgctct
     8041 acccgtttga tttgaccaag gcgagtcgct gcaaagtagg ttgtcgcatc gtcaaactga
     8101 tccagtactt ccacataaag gattgcttca ttcgtttcaa agtttgtgat ggtttggctc
     8161 agatgctctc cgatgtcctt ccaacgaata tctgccaact catggattgg tctgtagatg
     8221 acatttccaa gacttgtgaa catcaagagg tgctgggttg tcttggcaga ttgaacaaaa
     8281 atcaaacggt catcatcacg cttgccaatt tcttccaagg tggaagccgc aaaggaacgt
     8341 ggactggtac gcttgatgta acctgccttg gtcacgctga cgtaggtatc ttcctcagcg
     8401 ataagactag ctgtatcaat ctcaattgct ttcgcagtgt cttctaaaga actcaaacga
     8461 ggagttgcaa atttcttctt gacctcacga agttctttct tcatgagatt gtacatagtc
     8521 ctttcatcac cgataatagc caccagcata gcaatcttct cacgaagctc tgcttcttct
     8581 tcctgcaaga caaccacatc ggtattggtc aaacggtaca gttgcaaagt tacgatagcc
     8641 tcagcctgtt cttccgtaaa atcatagcta actttgaggt tttccttggc gtccgcctta
     8701 ttctcagaag cacggataag agcaatgact tcatccaaaa tcgaaatcac acgaatcaaa
     8761 ccttcgacga tatggagacg tttctcagcc ttttctttgt caaagcgtga acgcgccaaa
     8821 atcacttctc gacggtgagc gatgtagcta gacaggattg gaacaatccc aacctgacga
     8881 ggtgtgaaat tgtcaatcgc caccatatta aagttgtagt tgatttgtag gtcggtgtac
     8941 ttaaataagt agttgagaac aagctcagta ttagcgtctt tcttaagttc gatagcgata
     9001 cgaagaccat cacggtcaga ctcatcacga acctcagcaa tcccagctac cttgttatta
     9061 acacgaacat catcgatttt cttgactaga ttggccttat tgatttcata aggaatctca
     9121 gtaataacga tttgttcctt accacctttt agcttttcaa tttcagtctt ggaacgaaca
     9181 accacgcgcc ctttcccagt ctcataagct ttcttgattt catcacgacc ctgaataata
     9241 gcccctgtag ggaagtctgg tccaggcaag aattccatga gtttatcaat ctttgcagtt
     9301 gggtggtcaa tcatgtaaac tgcagcatct atgacctcag ctaaattatg gggaggaatg
     9361 tctgtggcat aaccagccga aatcccagtc gaaccattga ccaagaggtt tggaaaggct
     9421 gctggcaaga ccgttggttc tttctccgta tcgtcaaagt tccatgcaaa aggaactgtc
     9481 tttttctcga tatcctgaag aaggtagcct gcaatttcag acaaacgtgc ctcagtataa
     9541 cgcatagccg caggaggatc tccgtccata gaaccgttat taccgtgcat ttcaactaga
     9601 atctcacgat ttttccagtt ctgtgacata cgaaccatgg catcatagat agaagaatcc
     9661 ccgtgtgggt ggaaattccc catgatgttc ccgactgact tggccgactt acggtagctc
     9721 ttgtcaaaag tattgctatc cttattcata gaataaagaa tacggcgctg aaccggcttc
     9781 aacccatcac gaatatctgg caaagcccgg tcttgaataa tgtacttgga gtagcgacca
     9841 aagcgctctc ccatgatgtc ctccagggac atgttttgaa tgttagacat aagatacaaa
     9901 gcccataaaa taccaagtga aaatagaaaa ttcttgaagt aagcaaactc acaagagaat
     9961 ttatcttttt cacacagtat ctagggcgtg ttcaactcct ttcaaagaat gtagagtagg
    10021 tttttatgca gtaaaagata ttttacggga attcgtcccg tgttcagtta cgataagtaa
    10081 ccaaactatc ctgtttgtat ttttcaatat gaaaatatgg ttttccaaaa ttagtcttag
    10141 tttgtgtctt agccgctccc ttaaacgcct ctttgagata agcactcata gcagattctt
    10201 cattaataat cctgcaattt tttcaaacca agattttcaa actgcttttt cacatagtca
    10261 ttcacatccg actctaattt ccagtttact aacatattat tttctttcat taaaacactg
    10321 tcgcttcttc tagcgtaaac ttgacattat cttcaatcca tttacggcgt ggttctacct
    10381 tatctcccat gagaacattg acgcggcgtt cggcgcgcgc taaatcttca attgtgacac
    10441 ggatgagggt acgtgtttct gggttcatgg ttgtttccca gagctggtcc gcattcatct
    10501 caccaagtcc tttgtatcgt tggagggtag cgcctttacc gaactgttta cggagttctt
    10561 ctagttctcc gtccgtccaa gcgtaggcca cttcttcttt cttgccttta cctttggaca
    10621 tcttgtaaag aggtgggagg gcaatataga catgacctgc ctcgactagc ggacgcatgt
    10681 aacggtagaa aaatgtcaag agcaaggtct ggatatgggc accgtcggta tccgcatcgg
    10741 tcatgataat gatcttatca tagttggcat cttcaataga gaagtctgct ccaacacccg
    10801 caccaatggt ataaatcatg gtattgatct cttcattttt gaggatatcc gccatcttgg
    10861 ccttggctgt attgacaacc ttaccacgaa gaggtagaat agcctggaac ttgcggtcac
    10921 gaccttgttt ggcagaacca ccggcagagt ccccctcaac tagatagagt tcattcttag
    10981 caggattctt agattgggct ggggtcaatt tcccagacaa caagccctta tctttcttgt
    11041 ttttcttccc atttcggctc tcatcacgcg ccttacgtgc tgcttcacga gcatcacggg
    11101 ccttgatagc cttgcggatg aggttagaag ctaattcccc attttccata aggaaaaagg
    11161 tcaacttatc agccactatt ccatccacaa ctgggcgagc tagggggctt cctagtttat
    11221 ccttggtctg tccttcaaac tgcaagtgtt cttcaggaac taagatagaa agaacggccg
    11281 ctagtccctc acgatagtct gaaccttcaa ggtttttatc tttttccttg agaagacctg
    11341 ttttacgtgc atagtcattc atgaccttgg taatggcaga cttgagtcct gtctcgtgcg
    11401 ttccaccgtc cttggtgcga acgttattga caaaggatag aatgttatct gagaatccgt
    11461 cattgtactg gagggctact tccacttgaa aaccattgtc ttccccttca aagtaaagaa
    11521 ctggcgtcaa gatttcctta tcttcgttga gataagaaac aaaatcttgt actccattct
    11581 catagtggaa ctcaatcgct tcatctgttc gcttgtccgt taaagacaag gtcacatttt
    11641 tcaagagaaa ggctgattca ttaaggcgct ctgaaatggt attgtacttg aaatctgtcg
    11701 tagaaaagat agtcgcgtca ggcataaaag taactttggt gcctgtttta gacttgggtg
    11761 ctgtaccgat tttcttcaaa gtcgtgacag gttttccacc attttcaaaa cgttgcttgt
    11821 aaactgcgcc atcacgggta atttcaactt ctaaccagct agaaagggcg ttaacaacgg
    11881 aagaacccac tccgtgaagt ccacctgatg tcttatagcc accttgaccg aatttccctc
    11941 cggcatgaag aatggtaaag ataacctcaa cagttggaat tcccatagcg tgcatacctg
    12001 tcggcatccc acgtccatgg tcttgaaccg ttagactacc gtctttattg atagttacat
    12061 caatacgatc accaaaccca gacaaggctt catcgactgc attatcaacg atttcccaaa
    12121 ctaggtgatg aagaccagcg ccatcggtcg atccaatata catccctgga cgttttcgga
    12181 ccgcatccaa cccttctagc acctgaatag catcatcatt ataattgtta atattgattt
    12241 ccttttttga cacaaggaac ctcctattcg ttcatcttta ctattctaca ggttttccaa
    12301 ggattttgca aaatttttct ttctccgatg tgacaatttc agcagagatt ctctgctttt
    12361 ctttcccaat tcatgatata ataggagtat gattacaata gttttattaa tcctagccta
    12421 tctgctgggt tcgattccat ctggtctctg gattggacaa gtattctttc aaatcaatct
    12481 acgcgagcat ggttctggta acactggaac gaccaacacc ttccgcattt taggtaagaa
    12541 agctggtatg gcaacctttg tgattgactt tttcaaagga accctagcaa cgctgcttcc
    12601 gattattttt catctacaag gcgtttctcc tctcatcttt ggacttttgg ctgttatcgg
    12661 ccataccttc cctatctttg caggatttaa aggtggtaag gctgtcgcaa ccagtgctgg
    12721 agtgattttc ggatttgcgc ctatcttctg tctctacctt gcgattatct tctttggagc
    12781 tctctatctt ggcagtatga tttcactgtc tagtgtcaca gcatcgatcg cggctgttat
    12841 cggggttctg ctctttccac tttttggttt tatcctgagt aactatgact ctctcttcat
    12901 cgctattatc ttagcacttg ctagtttgat tatcattcgt cataaggaca atatagctcg
    12961 tatcaaaaat aaaactgaaa atttggtccc ttggggattg aacctaaccc atcaagatcc
    13021 taaaaaataa aacgccagtt ctgtactgcc cccaaacagt tagacaaata atttatggct
    13081 ctttgtcaac tgtagtgggt tgaagaaaag ctaagctcga gaaaggacaa attttgtcct
    13141 ttcttttttg atattcagag cgatgaaaat ccgttttttg aagttttcaa agtttcgaaa
    13201 accaaaggca ttgcgcttga taagtttgat gagattattg gtcgattcca gtttggcatt
    13261 agaatagtgt agttgaaggg cgttgacaat cttttcttta tctttgagga aggttttaaa
    13321 gacagtctga aaaataggat gaacctgctt aagattgtcc tcaataagcc cgaaaaattt
    13381 ctctggttcc ttattctgga agtgaaaaag caagagttga tagagctgat agtgatgttt
    13441 caagtcttgt gaatagctca aaagcttgtc taaaatctct ttattggtta aatgtatacg
    13501 aaaagtagga cgataaaatc gcttatcact cagtttacgg ctatcctgtt gtatgagctt
    13561 ccagtagcgc ttgatagcct tgtattcatg gaattttcga tgaaactgat tcatgatttg
    13621 aacacgcaca cgactcatag cacggctaag atgttgtaca atgtgaaagc gaagctgttt
    13681 agccaagcca tagtaagggc taaacatatc catagtaata attttgacgc gacatcggac
    13741 aactctatcg tagcgaagaa agtgatttcg aatgatagct tgtgttcttc cctcaagaac
    13801 agtgatgata ttgagattgt taaaatcttg cgcaatgaag ctcatctttc cctttgtaaa
    13861 agcatactca tcccaagaca taatctcagg aagacaagaa aaatcatgtt taaagtgaaa
    13921 atcattgagc ttacgaataa cagttgaagt tgagatggaa agctgatggg caatatcagt
    13981 catagaaatc ttttcaatta acttttgagc aatcttttgg ttgatgatac gagggatttg
    14041 gtgattcttc ttgacgatag aagtttcagc gaccatcatt ttagaacaat gatagcactt
    14101 gaatcgacgc tttctaagga gaattctagt aggcatacca gtcgtttcaa gataaggaat
    14161 tttagaaggt ttttgaaagt catatttctt caattggttt ccgcactcag ggcaagatgg
    14221 ggcgtcgtag tccagtttgg cgatgatttc cttgtgtgaa tccctattga cgacatctat
    14281 aatttggata tttgtgtctt tgatatcgag tagttttgtg ataaaatgta attgttccat
    14341 atgaatcttt ctaatgagtt gttttgtcgc ttttcattat aggtcatatg ggactttttt
    14401 tctacacaaa aataggctcc ataatatcta taggggattt acccactaca aatattatag
    14461 agcctaattt atccgaagga tttagttctg tattgcacag ggctaagtcc ttttagtttt
    14521 atcttaattc tcttattgtt gtagtaatca atatagtcta caatagcttg ttccaattgc
    14581 ttaagcgact gaaacgactt ctcataaccg taaaacattt ccgatttcag aatcccaaag
    14641 aaggactcca tcataccatt gtctgggctg ttacccttac gtgacatgga tgcttgaact
    14701 cccttactct ctaggaaccg atgataagaa tcgtgtcggt attgccagcc ttggtcacta
    14761 tggagaatcg tattctcgta gtgcttctct gtaaaggcct gttctaacat actcttcact
    14821 tgttctaagt tgggcgaagt tgaaagatta taggcgataa tttcgctatt aaagccatct
    14881 aaaactggtg ataagtaaag cttttgagta cttgctggaa tggcaaattc tgtcacatct
    14941 gtgtagcact tttccattgc tttagagcct tcaaattggc cttgaatgag attctctgcc
    15001 ttcttaccaa cgtctccttt attttcgttt ctgtcgcatt ttagcttgta aattgagtac
    15061 ttttatcaag ccttgaactc ttttatgatt taccagataa gcacgatttc ttagttctaa
    15121 atgaatacag cgataagcat aatttccctt gtgttcgata aaaatggatt gaatttcagc
    15181 tttaagctct tggtccttat ctggtttgtc tagctgtttc aagtgatagt agtaggtcga
    15241 acgagctagt ttaatggctt ttagaagaag atctaacgaa aactcagtca ttaattcttg
    15301 aacaatttct gtctttcttc tttctctttt tcctccttca atcggagttc tcttaacttt
    15361 tttaggatgg cattctccgc tctcaggtac tcattttctg attgaagacg ttctaattct
    15421 gtcctctctt caggtctcgt ttttggatta cgtcccattt taggtactct cc
//
LOCUS       DAVKBC010000041        14116 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVKBC010000041 DAVKBC010000000
VERSION     DAVKBC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.041"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            81..878
                     /locus_tag="VWX64_001611"
     CDS             81..878
                     /locus_tag="VWX64_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU9191049.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1026..2285
                     /locus_tag="VWX64_001612"
                     /pseudo
     CDS             1026..2285
                     /locus_tag="VWX64_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2381..3655
                     /locus_tag="VWX64_001613"
     CDS             2381..3655
                     /locus_tag="VWX64_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU9191050.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIENFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKEHDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKVQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3665..4543
                     /gene="truB"
                     /locus_tag="VWX64_001614"
     CDS             3665..4543
                     /gene="truB"
                     /locus_tag="VWX64_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU9191051.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAADLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4784..5086
                     /locus_tag="VWX64_001615"
     CDS             4784..5086
                     /locus_tag="VWX64_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9191052.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMADLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5194..5832
                     /gene="udk"
                     /locus_tag="VWX64_001616"
     CDS             5194..5832
                     /gene="udk"
                     /locus_tag="VWX64_001616"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU9191053.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5960..7300
                     /locus_tag="VWX64_001617"
     CDS             5960..7300
                     /locus_tag="VWX64_001617"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU9191054.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSRIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7278..7490
                     /locus_tag="VWX64_001618"
     CDS             7278..7490
                     /locus_tag="VWX64_001618"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU9191055.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7487..8362
                     /locus_tag="VWX64_001619"
     CDS             7487..8362
                     /locus_tag="VWX64_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU9191056.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVGLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8355..9170
                     /locus_tag="VWX64_001620"
     CDS             8355..9170
                     /locus_tag="VWX64_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU9191057.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLVYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9163..9594
                     /locus_tag="VWX64_001621"
     CDS             9163..9594
                     /locus_tag="VWX64_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9191058.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9601..11268
                     /gene="recN"
                     /locus_tag="VWX64_001622"
     CDS             9601..11268
                     /gene="recN"
                     /locus_tag="VWX64_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU9191059.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11270..11998
                     /locus_tag="VWX64_001623"
     CDS             11270..11998
                     /locus_tag="VWX64_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU9191060.1"
                     /translation="MTDYYVVGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12077..13900
                     /gene="lepA"
                     /locus_tag="VWX64_001624"
     CDS             12077..13900
                     /gene="lepA"
                     /locus_tag="VWX64_001624"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU9191061.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRLSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13981..>14116)
                     /locus_tag="VWX64_001625"
     CDS             complement(13981..>14116)
                     /locus_tag="VWX64_001625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191062.1"
                     /translation="TRKLAAGCSKHSFEVVDETDEVSNHTYGKATLTWFEEIFEEYKN
                     "
BASE COUNT         4153 a         2580 c         3376 g         4007 t
ORIGIN      
        1 ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa
       61 aaaagattta ggagtttatt atggtttctt cagaatttat ttcaaagatt gaatttgctt
      121 gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatgt
      181 tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc agttggggct gacttgatta
      241 ataaaattgc accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg
      301 cctacattgt ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg
      361 gtagtttctt aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct
      421 tgttcaacct tatcggagcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg
      481 cgaatctgac acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa
      541 atgaattggt tttgcttgag gcgattttgg caaatatttt cgtaaatatt gcgattctgt
      601 catttatttt ggtcaaagat ggtggtgcca aactttggct tgtgttgtca gctatttaca
      661 tgtttgtatt cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga
      721 aattcagtgt tgctgcggat tcaattgcca acttcggtgt tggaaatatg cttcgccact
      781 ggggtgtgac tttcatcgga aactttatcg gaggaggcct cttgatgggt cttccatatg
      841 ccttcctcaa taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg
      901 tgcttttttc attttcaaaa taagataata gctatttctt atatcaaaat atagaaaact
      961 gatatttgta aactataact caaggtgcta caatatcctt aataaaataa tatggaggtc
     1021 accttatgac tcgtgatttt aaatttgaaa ctctacaact acatgctgtt caagttgtgg
     1081 ctccagctac taagtctcgt gcagtgccga tttatcaaac aacatttttt gtttttgatg
     1141 acacgtagga aggtgccgat atgtttgcct tgaggaaacc agggaacatt tatactcgta
     1201 tcaccaatcc tacaacagct gcccttgaag gtggtgttga agcgctagca acagcatcag
     1261 gtatgactgc agtgacttat acgattttgg cgattgccca tgctggtgac catgtagtgg
     1321 ctgcttcgac tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg
     1381 gtatcacaac aacctttgtc gatattgata atttggagga agtagaagca gctatcaaag
     1441 acaataccaa gcttgtcttg attgaaacct tgggtaaccc cttgattaat attccagacc
     1501 tggaaaaact ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt
     1561 ttgcaacacc ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg
     1621 cgactaagtt tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggta
     1681 gttttgactg gacggcttca gggaaattcc ctcaatttgt tgacgagggt ccaagctgcc
     1741 acaatttgag ttatactcgt gatgtgggtg cagcagcctt tattatagct gttcgagttc
     1801 aattgcttcg tgatacaggt gcagccttgt caccattcaa tgctttcctc ttgctacaaa
     1861 gacttgaaac cctttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg
     1921 attttcttgt caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc
     1981 cttatcatgc cttggctgag aaatacttac caaaaggtgt gggctcaatc tttaccttcc
     2041 atgtcaaagg tggggaggcc gaagcccgca aggtcattga taatttggaa atcttctcag
     2101 accttgctaa cgtggcagat gccaagtctc ttgttgttca tccagcaaca accactcacg
     2161 gtcaattgtc agacaaagac ctagaagccg caggtgttac accaaaccaa atccgcttgt
     2221 cgatcggact tgaaaatgta gaggatttga ttgaagattt gcgcttggcc ttggaaaaaa
     2281 tttaaagtaa aagaagatag acagtggttt tcgactcgct gtttttgatt ttccttcatg
     2341 catgatataa tggttacaga agtctagaaa gaggaatgta atgaacgaaa tcaaatgtcc
     2401 caactgtggg gaagtcttta cagtaaatga aagccagtat gctgaacttt tgtcccaagt
     2461 gagaacggca gagtttgata aggaactaca cgataggatg aggcaggaac tggccttggc
     2521 tgagcaaaag gctatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc
     2581 gcaattacag agtcagatcg aaaactttga tacagaaaaa gaattggcca agaaagaagt
     2641 tgaacagaca agccatcagg ccttattggc taaggacaag gaagtacagg ctttggagaa
     2701 ccaattggcc actttgcgtt tggagcatga aaatcaactg caaaagaccc tttctgacct
     2761 agaaaaagaa catgatcagg tcaaaaatca gctcctcttg caagaaaagg aaaatgagtt
     2821 gtctttggct tctgttaagc aaaactatga agcccagctt aaagcagcta gtgaacaagt
     2881 cgagttttat aagaatttta aggttcaaca atctacaaaa gcgattgggg aaagcctaga
     2941 acagtatgca gagagtgagt ttaacaaggt tcgtagtttc gcctttccaa atgcttactt
     3001 tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg
     3061 tgatgaaaat ggagttgaaa tcatttctat catgtttgag atgaaaaacg aagcggacgg
     3121 aacagagaag aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga
     3181 gaagaactgt gagtatgccg ttttggtgac catgcttgag gctgataatg actactttaa
     3241 cacagggatt gttgacgtca gtcacgagta tgaaaaaatg tatgttgttc gtcctcaatt
     3301 ctttatccag ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca
     3361 ggagttggcc ttggttcgcg agcaaaatat tgacattacg cattttgagg aagacttgga
     3421 tgcctttaag ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc
     3481 tattgatgaa atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgaccac
     3541 atctgaaaac caactccgtt tagctaacaa caaattggaa gatgtctctg ttaaaaaatt
     3601 gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc
     3661 aaaaatgaac ggtattatca acttaaaaaa agaagcagga atgacctcgc atgatgcggt
     3721 ttttaaactg cgtaagattt tgggaaccaa gaaaattggt catggtggaa ccttggatcc
     3781 ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat
     3841 gcaggacgag gggaagatct atgaggggga aattactctg ggctattcca cgacgactga
     3901 ggatgctagt ggggaagtgg tcgcagaaac ccctgttttg tctcccttgg atgaaaagct
     3961 tgttgatgaa gcgattgcta gcttgactgg gcctattacc cagattcccc ctatgtattc
     4021 ggcagttaag gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga
     4081 gcgtccagaa cgtcaggtga ccatttatca atttgagcga acaagtccga tttcttatga
     4141 tggccaactt gcccgattca cttttcgtgt aaaatgcagt aaagggactt acatccgtac
     4201 tttgtcagtt gatttgggtg aaaagcttgg ttatgcggct catatgtccc atttgactcg
     4261 tactagtgct gctgacttac aattagaaga cgctcttgcc ttggaggaaa ttgctgaaaa
     4321 agtagaggct gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt
     4381 caaagttttc ctaactccag aagaggctac agaagttcgc tttggtcgtt ttattgagct
     4441 agaccaaacg gataaagaac tggctgcctt tgaagatgat aaattgttag ccattctaga
     4501 aaaacggggc aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa
     4561 atcgggtgat agataacaat tgcttgataa aaccccatac taatagtaga atggttttgg
     4621 gaattataat attccaattg ttgcgagttg taggtactca aataatctat atagaaattt
     4681 agaggtgtga aatgaagcaa tttaaaattc tttcagataa atatttagag tccattacag
     4741 gttctggtgg gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt
     4801 tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag
     4861 tcacctgttt cgtcttgcta tacaaaattt agacagaaat gaaaaacacc aatcggtcat
     4921 ggccgatttg agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa
     4981 gtctgtcatt gattttggtt tatggattgc caaagctcct agccaggaaa gagggagact
     5041 ggctttcttg cagatgcttg ctcaaaccct acagggcttt cgttaaaact gtcgaacatc
     5101 agagggaaga ctctggtgtt ttttgctgat gagactataa attttgtaaa aaatgtgata
     5161 gaatagacga cggataaaat aacggaggat agcatgcaaa atagaccaat cattattgga
     5221 gtgacaggtg gttctggtgg tggtaaaacc agtgtttcaa gagccatttt atcgcatttt
     5281 cctgatgaaa agatttccat gattgagcat gattcatact acaaggatca gtctcatttg
     5341 acctttgaag agcgtgtcaa aaccaactat gaccatcctt ttgcctttga tacagacttg
     5401 atgatcgagc agattaagga attgttggca gggcgtccgg tggacatccc gacctacgac
     5461 tatacagagc atacacggag tagcaagacc tatcgtcagg agcctcaaga tgtctttatc
     5521 gttgagggca ttttggtctt ggaggacaag cgtctgcgcg atttgatgga tatcaagatt
     5581 tttgtggata cggatgacga tgtgcgtatt attcgtcgta tcaagcgtga tatggaggag
     5641 cgtggccgta gccttgatag cgttatcaac cagtacttag gtgtggtcaa accaatgtac
     5701 caccagttta tcgagtcaac taagcgttat gctgatatcg tcattcctga aggggttagc
     5761 aataccgtgg ctatcgacct gttgacgacc aagattgcaa agattttgga agaagctcga
     5821 aacagcaaat aatcacatgt ggaggccttg cctccttttt ctatttttcc ctcataatgg
     5881 tacataaatg gagattttta ggcatatttt tggtataata atacccatga aagagcaagt
     5941 aaatgaatag taggtggaga tggaaaagta tttatcggta acaactttga ccaagtatct
     6001 gaaaatgaaa ttcgataaag acccatactt ggaacgggtc tatttaactg gtcaagtttc
     6061 caactttcgt aaacgaccta ctcaccaata tttctcccta aaggatgacc atgcagttat
     6121 tcaagcgacc atctggtcta ggatttatca gaaattaggg tttgacctgg aagaaggaat
     6181 gaagatcaat gtgattgggc gtgtacaggt ctatgaacca agtggtagct actccatcat
     6241 cattgaaaaa gctgagcctg atggggttgg ggcgcttgcg attcagtttg aacaacttaa
     6301 gaaaaaattg acagaagaag gcctgtttca agaacgcttc aagcaagctc tgccccaatt
     6361 ttctaagaga attggtgtag taaccagccg tagtggagcc gttattcgag atattatcac
     6421 gaccgtcagc aggcgattcc caggtgttga catccttctt tatccgacca aggttcaagg
     6481 tgaaggggct gcggaggaaa ttgctagaaa tattgcgcgt gctaatcaac gggacgattt
     6541 ggatttgctc attattggtc gtggaggtgg ttctattgag gatctctggg cctttaacga
     6601 agaaattgtg gtacgagcta tttttgaatc tcgtttgcca gttatctcta gtgtggggca
     6661 tgagacggat gtgaccttgg cagattttgt ggcagatcga cgcgctgcaa cgccaacagc
     6721 ggcggctgaa ctggcaacac ctgtgaccaa gttggatgta ttagctcatt tgcaaaatca
     6781 ggaaaaacgg atggtaacgg cagtccgaaa tgttctatct aagaaacaag aggctttgaa
     6841 aaaatgcagt cagtctgtta tctttagaca acctgagcgc ttgtatgacg gttatttgca
     6901 acgcttggac caactgcaac tgcgtttgaa acaaagtttg cgaactcgga tttctgataa
     6961 caaacaatta gttcaagcaa gaactcatca attagtacaa ttatcacctg ttaccaaaat
     7021 ccaacgctat caagaccgtt taggacagtt ggacaagctc ttaggtagcc aaatggcgtt
     7081 agtttatgac gccaaggttg ctgaggccaa gcgactttcg gaagctttgc tcatgttgga
     7141 tactagccga atcgtggcgc gtggttatgc tattgtcaaa aaagaagagt ccgttgtaga
     7201 ttcggttgag agtttgaaga aaaaagacca agtaacgctt ttgatgcgag atggtcaagt
     7261 agaattagag gttaaagatg tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg
     7321 aaaccattgt ccaaagtttg gaaaatggtg aaattgctct ggaagatgcg attactgcct
     7381 ttcaaaaggg catggtcttg tcaaaagagc tccaagctac gctggacaag gctgaaaaga
     7441 ccttggtcaa ggtcatgcaa gaagacggaa cagaaagtga ttttgaatga aaaagcaaga
     7501 aaaattagct cttgtcgagt cggctttgga agatttttat ggagaccagc agtttgcctc
     7561 tagtttacgg gagtctgttc tctattctat tcatgctggt ggcaagcgta ttcggccttt
     7621 tctcttgtta gaagttctgg aagccttgca ggttaccatc aaacctgctc acgcgcaggt
     7681 agctactgcc ttggagatga ttcatacagg gagcttgatt cacgatgacc ttcctgctat
     7741 ggatgatgac gattatcgaa gagggcggtt aaccaatcac aagaaattcg gtgaagctat
     7801 ggccattttg gctggagatg ccttattctt agacccatat gccttgattg cgcaggcaga
     7861 tttgccaagt cagatcaagg tgggcttgat tgccaactta tcccttgctt caggtagtct
     7921 gggtatggtg gcagggcaag ttttggatat ggagggcgaa caccagcact tgtctctgga
     7981 agaacttcag actattcatg ccaataagac tgggaagtta ctagcctatc ccttccaagc
     8041 ggcagctatt atagctgaat tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga
     8101 attgattgga cttgcttttc aagtcagaga tgatgtactg gatgtgacgg ctagttttga
     8161 ggaaatcggc aagacacctc aaaaggatct gcaggcagaa aaatcaacct atcctgcctt
     8221 gttgggcttg gaagagtcca ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa
     8281 attagaagaa attgcccagc agcttccctt tgaaacagaa tcgattgtaa gtgtagtaga
     8341 aagtttgaga atcaatggct aaggaaagag tggatgtact agcttataaa caggggttgt
     8401 ttgaaacgag agagcaggcc aagcgaggtg tgatggctgg cctagtcgta gcagtcctta
     8461 atggagaacg gtttgacaag ccaggagaga aaattccaga tgacaccgaa ttaaaactca
     8521 agggggagaa actcaagtat gtcagccgtg gtggtttgaa actggaaaag gccttgcagg
     8581 tctttgattt gtcggtggat ggcgcgacta cgattgatat cggggcctct actggaggtt
     8641 ttaccgatgt catgctacag aatagtgcca agttggtctt tgcagtcgat gttggtacca
     8701 atcagttggc ttggaaatta cgccaagacc cacgagttgt cagcatggag cagttcaatt
     8761 tccgctatgc tgaaaagact gatttcgagc aggagccgag ctttgccagt attgatgtga
     8821 gtttcatttc ccttagtctg attttgccag ccttgcaccg tgtcttggct gatcaaggtc
     8881 aggtggtagc acttgtcaaa cctcagtttg aggcaggacg tgagcagatt gggaaaaatg
     8941 gaattattcg agatgctaag attcatcaga atgtccttga atctgtaaca gctatggcag
     9001 tagaggcagg tttttcagtc cttggcttgg acttttctcc catccaaggt ggacatggaa
     9061 atattgaatt tttagtgtat ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg
     9121 agattaaaga agcagtagag agggcgcata gtcaatttaa aaatgaataa aaaagagaga
     9181 cttgaaaaaa ttagaagatt ggtgacagat tatcaaatcg gcacgcaaga agaaattgta
     9241 gaacatttga aagaagcagg tatcactgcc actcaggcga cggtatcccg agatatcaaa
     9301 gagttaggta ttgtcaaaat tcctttgaga gacaacacct atgtctacga attgccaaaa
     9361 tcaatcgtaa aaagtctgca actggctgaa gacaatatcg aatcggctga attgatggat
     9421 aagatgatca atctccaagt tattccagga aatacggctt ttgtaaaagc tcagttaatc
     9481 gagacttttg cagacaagat ttttagctgt ttgactgatg atagctcgat tttagtcatt
     9541 gccagaagtg gaagtctagc agaggaaatc tttgaacaag taaaaaattg gtaggtctat
     9601 atgttacttg aaatttcgat aaaaaacttt gccattattg aggctatttc cctcaatttt
     9661 gaaaagggga tgactgtcct gactggtgaa acgggtgcag ggaagtcgat tatcattgat
     9721 gccatgaata tgatgttggg agctcgtgcg acgacagatg ttattcgtca tggtgcacca
     9781 aaggcagaga ttgaggggct tttctcagtt gagaatagtc gtcttttaca ggaaattttt
     9841 gatgagcaag gtttagaatt aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat
     9901 ggtcgtagta tcagccgtgt aaatggtcag atggttaatc tgtctgtttt gcgagctatt
     9961 gggcaacatc ttgtagatat tcatggtcag catgaccatg aggagttaat gcgtccccaa
    10021 ctgcatatcc agatgttgga tgaatttggt gatgccgctt tttgggactt gaaagaaacc
    10081 tatcaaacga gttttgatgc ctatcggaaa atgcgcaagc aggttctgga agtcaagaaa
    10141 aaccaacagg aacacaaggc acgtatcgaa atgttggaat ttcaaatggc agagattgag
    10201 gcagcaaact tgcaggctgg agaagacttg gctctcaatc aagagcgaga taaactcctc
    10261 aaccacaaaa atattgcgga tacactgacc aatgcctaca gtatgttgga caatgaagat
    10321 ttttcaagtc tggccaatgt tcgttcagct atgaatgaca tggaaagtgt cgaagagtat
    10381 gatcctgaat accgtgaaat ttcaagctct ctgtctgaga cctactatgt tttagaagac
    10441 attagcaaac gtttggaagc tatcattgag gaccttgatt ttgatggcaa tcgcctgatg
    10501 caggttgaga atcgtttgga cctccttcat actattactc gtaagtatgg tgggactgtt
    10561 gatgatgttt tgctttattt tgccaagatt acggaagaat acaatctctt gacaggcaat
    10621 aatctttcgt ctgaggacat ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat
    10681 ttggcaggtc aacttgcttc tgctcgtcat aatttggctc agcaactcga agctgagatt
    10741 aaacaagaac tgcaagatct ttatatggaa aaagcccagt ttcaggttcg ttttagtaag
    10801 ggaaaattca gtcgtgaggg aaataaaatg gttgagtttt atatttcaac caaccctgga
    10861 gaagacttta aacccttggt taaggttgct tctggagggg aattatctcg tctcatgtta
    10921 gccattaagt ctgccttttc acgtaaagaa ggcaagacta gcattgtctt tgatgaggtg
    10981 gatacgggag tttcaggtcg tgttgctcaa gctattgctc agaaaattca taaaattggt
    11041 cagcatggtc aggttttggc tatctcccat ttgccacaag taattgcgat tgcagattat
    11101 caattcttta ttgagaagat tagtaatgac cattcaacgg tttcgactgt tcgtctcttg
    11161 acggtcgaag agcgagtgga ggaagttgcc aagatgttgg caggtgatga tgtgacagaa
    11221 gcagccctga cgcaagccag agaattgttg agaaacaggg agaaataaga tgacagatta
    11281 ttatgtagtt ggagatgttc acggaaaagc tgggatgctg gaagaccttc tcaaaacctg
    11341 ggatggtcag ccccagttgc tctttctagg tgatttgatt gacagaggtg aggatagtca
    11401 ccgtgttctt gaaatggtca aggacttggt ggacaatcaa ggggctatct gtttgtccgg
    11461 aaaccacgag tatatgtttt tgacttggct agatgaccca gaagaaagtt atgaccatta
    11521 tagtcgcaat ggtggagata caaccattaa ctctatccta ggtcgtccct tggatgcacc
    11581 agttgatgga gtagaagatg ccaagcgggt tgccgctgaa gcgtcagact tggtcgaatt
    11641 cattcgtcaa atgccatttg tagtagagac agacaagtat atatttgttc acgcaggtat
    11701 tgatttgact ttggacgact ggcatgaaac aacagattat aaaaaagtat ggcttagaaa
    11761 accattccac ggagctgaaa atcatactgg aaaaaccatt gtcttcggtc atacaccggt
    11821 ctatggtttg ttacagcaag aacgcggtac atctgagctt tggactacag aagatggcaa
    11881 gattggaatg gatggaggag ctgtttatgg tggtgtcctt cacgggattg tctttacaga
    11941 ccaaggaatg acagaacacc actttatcga aaatgacggc tttgtcgctg aagattagta
    12001 ctcctagcag ggtatggtct tgtcaaaata tcaaaaacaa tttataataa atagataccc
    12061 tgaaaggaag agaatcatga acttagaaga attgaaaaaa cgacagggga agatccgtaa
    12121 cttctctatt atcgcccata ttgaccacgg gaaatcaact ctagcagacc gcattttgga
    12181 aaaaacagag acggtttcaa gtcgtgaaat gcaggcccag cttttggata gcatggatct
    12241 agagcgggaa cgtggaatta ctattaagtt gaatgccatc gagttgaatt acactgcaaa
    12301 agatggggaa acttatattt tccacttgat tgacacacca gggcacgttg actttaccta
    12361 tgaagtttca cgttcgctag ctgcctgtga gggtgctatt ttggtggtcg atgcggctca
    12421 aggaattgag gctcaaactc ttgccaacgt ttatctggct ttggataatg atttggaaat
    12481 catgcctatc attaataaaa ttgacctgcc ggctgcagat ccggagcgcg tgcgtacaga
    12541 gattgaagat gtgattggtt tggatgccag tgaagcagtt ttggcttctg ccaaggctgg
    12601 tattgggatt gaagaaatcc tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga
    12661 tgtgacggcg ccacttaagg ccttgatttt cgactctgtt tacgatgctt accgtggggt
    12721 tatcctccaa gtgcgtgtca tggacggagt ggtcaaacct ggtgataaga ttcagctcat
    12781 gagcaatagt aagacctttg atgtggccga agtcggtatt tttacaccaa aagcggttgg
    12841 tcgtgatttc cttgcgactg gtgatgttgg ttacattgcg gcgtctatca agacggttca
    12901 ggatactcgt gtgggtgata ccgttacctt ggcaaccaat cctgcggcag aaccattaca
    12961 tggttataag cagatgaatc ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa
    13021 gtacaatgac ctgcgtgaag cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt
    13081 tgaaccagaa acatctcagg cacttggatt tggtttccgt tgtggatttc ttggacttct
    13141 ccatatggat gttattcagg aacgtttaga gcgtgagttc aatattgacc tcatcatgac
    13201 agctccgtct gttatttaca aagttaattt gaccgacggt gagtctatgg atgtgtctaa
    13261 cccatctgag tttccagacc caactaagat tgcgaccatt gaagagcctt atgtcaaggc
    13321 gcaaatcatg gtaccacagg agttcgtcgg agcagtaatg gagctagctc agcgtaagcg
    13381 tggggacttt gtgactatgg actatattga tgataaccgt gtcaatgtta tctatcaaat
    13441 tcctcttgct gaaattgtct ttgacttctt tgataaactt aagtcttcga cacgtggtta
    13501 tgcaagcttt gactacgaat tgtcagaata tcgcctatct aagctggtga aaatggatat
    13561 ccttctcaat ggagataagg tggatgccct cagctttatc gttcacaagg actttgccta
    13621 cgaacgtggg aaactcatcg ttgataaact caagaaaatc atccctcgcc aacaatttga
    13681 agttccaatc caagcggcta ttggacacaa gattgtcgct cgtactgata tcaaggccct
    13741 tcgtaagaac gtacttgcta aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct
    13801 tgaaaaacaa aaagctggta agaaacgcat gaaatccatc ggatcagttg aagttccgca
    13861 agaagccttc ctcagcgtct tgagtatgga tgaagaataa gttatcagaa atgcctttcc
    13921 ttgttcacag gaaatttata taaaaatcaa tagtaaagca ggcttagatg gtctgctttt
    13981 ttagttttta tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt
    14041 atggttactg acttcgtcag tttcatctac aacctcaaaa ctgtgttttg aacaacctgc
    14101 ggctagcttc ctagtt
//
LOCUS       DAVKBC010000042        13990 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVKBC010000042 DAVKBC010000000
VERSION     DAVKBC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.042"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(354..1109)
                     /locus_tag="VWX64_001626"
                     /pseudo
     CDS             complement(354..1109)
                     /locus_tag="VWX64_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(1247..2869)
                     /gene="groL"
                     /locus_tag="VWX64_001627"
     CDS             complement(1247..2869)
                     /gene="groL"
                     /locus_tag="VWX64_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU9191063.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2885..3169)
                     /gene="groES"
                     /locus_tag="VWX64_001628"
     CDS             complement(2885..3169)
                     /gene="groES"
                     /locus_tag="VWX64_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU9191064.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(3439..3834)
                     /locus_tag="VWX64_001629"
     CDS             complement(3439..3834)
                     /locus_tag="VWX64_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU9191065.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3911..4672)
                     /locus_tag="VWX64_001630"
     CDS             complement(3911..4672)
                     /locus_tag="VWX64_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU9191066.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKVNQGHVINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(4705..5331)
                     /locus_tag="VWX64_001631"
     CDS             complement(4705..5331)
                     /locus_tag="VWX64_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU9191067.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(5347..5664)
                     /locus_tag="VWX64_001632"
     CDS             complement(5347..5664)
                     /locus_tag="VWX64_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU9191068.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(5661..5960)
                     /locus_tag="VWX64_001633"
     CDS             complement(5661..5960)
                     /locus_tag="VWX64_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU9191069.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGAIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(6245..6436)
                     /locus_tag="VWX64_001634"
     CDS             complement(6245..6436)
                     /locus_tag="VWX64_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU9191070.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(6597..7271)
                     /locus_tag="VWX64_001635"
     CDS             complement(6597..7271)
                     /locus_tag="VWX64_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191071.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIEAILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(7277..7723)
                     /locus_tag="VWX64_001636"
     CDS             complement(7277..7723)
                     /locus_tag="VWX64_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9191072.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7837..8340)
                     /locus_tag="VWX64_001637"
     CDS             complement(7837..8340)
                     /locus_tag="VWX64_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9191073.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(8337..8699)
                     /locus_tag="VWX64_001638"
     CDS             complement(8337..8699)
                     /locus_tag="VWX64_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEU9191074.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDSLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(9008..9724)
                     /locus_tag="VWX64_001639"
     CDS             complement(9008..9724)
                     /locus_tag="VWX64_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9191075.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(10605..12020)
                     /gene="ply"
                     /locus_tag="VWX64_001640"
     CDS             complement(10605..12020)
                     /gene="ply"
                     /locus_tag="VWX64_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU9191076.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(12031..12363)
                     /locus_tag="VWX64_001641"
     CDS             complement(12031..12363)
                     /locus_tag="VWX64_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191077.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(12434..13042)
                     /locus_tag="VWX64_001642"
     CDS             complement(12434..13042)
                     /locus_tag="VWX64_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191078.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSRLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(13055..13513)
                     /locus_tag="VWX64_001643"
     CDS             complement(13055..13513)
                     /locus_tag="VWX64_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU9191079.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            13638..13990
                     /locus_tag="VWX64_001644"
                     /pseudo
     CDS             13638..13990
                     /locus_tag="VWX64_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4045 a         3169 c         2551 g         4225 t
ORIGIN      
        1 gttatagcag agttgtaaca catttctata aagaaattta ttcctacgac tcagtttggc
       61 atgcttaact tcctaactca aaaacaaagc atcgattaat ttatccgttc ttcttttgaa
      121 acagatttga actgataatt gctcgtttta atttaaaaag ctcttttgag caaaacttca
      181 tttttttaag agtccaacaa tttctgtcta tcgcttttct actagcaaaa aacctacctt
      241 gaggcaagtt ttcatttata tatctaattt cgtaacagta tagtaaaatg aaataaggac
      301 agtcaaatcg atttctaaca atgttttaga agtaaaggtg tactattcta gtttcaatct
      361 actataaatt tgatatgaga atagtctttc tcaacatcct tatccaacaa gcatgctgtg
      421 gcgtccttct taacttaaac caggtcaata ttctgggctt gggctgcata gacgcagcca
      481 caataacatt gacgatagat atcatactcc tcacacatct ctactgaacg tttgtagcct
      541 tgatttttct tgaaatcgtt gggaagatag tggggcgtgt aaattttttg cacatcgatt
      601 ccgatgctat tgatagtttg agaattctta tgaggactga tggtcaaggc tgaaccaaag
      661 tagtcaaagc ccaagtccat agccacttgc gctgttttat ccagtcggta gtcaaaacaa
      721 accttgcaac ggtcgccacc ttcgggctcc tcctctagcc ccctaactag ttttcggtat
      781 taattgggtt cgtagggagc ttctaggtac tgaaccgtat ttcctgtctg ctcattaaaa
      841 tcactaacaa atttcttggt gacatagacc cgcttatggt attctgcctt gggatggata
      901 ttagaattgg caaaatagat ggtcacatct gcatacttgg tcaaatattc tagtgtatag
      961 gtactacaag gggcacagca aacatgcacg agaatggttg gccgctactc atttttttcc
     1021 catgcttgta ccattttctg catgacacgg tcataattaa tcttctgatt gggggtcatc
     1081 ttgcacagaa tttcttctac atcgatcatg ttcttctcct ttttctagtc ttattttatc
     1141 atataagtta ggagagctca aatcaattta gaagtgaata ttataaaaag aagggttagt
     1201 cattccctcc ttttgtgttt tttataagtt gttttctata gaaagcttac atcatcccgc
     1261 ccatcatact tggatccatt gctggagctg gggctactgg ttctggttta ttggctacga
     1321 ctgcttctgt tgtcaaaatc aagctggcta cagatgctgc attttgtagg gctgaacgac
     1381 tcactttaac tggatcaatg ataccttgat caatcatgtt aacccactcg ccagttgctg
     1441 cgttgaatcc tataccaagc tcagcatttt tcaaacgatc gataacgata gatccttcaa
     1501 atcctgcatt gtgagcaatt tgacgaacgg gttcttccaa agcacggaga acaatattac
     1561 gtcctgttgc ttcatctcct gtcaattcca aggtagcaac agctggaatc acattggcaa
     1621 gagctgttcc accacctgca acaatacctt cttcaacagc tgcacgagta gcgttgaggg
     1681 catcttcaat gcggagtttc atttctttca actcagtttc agttgcggct ccgaccttaa
     1741 taaccgctac accacctgac aatttggcca agcgttcttg caatttttca cggtcaaatt
     1801 cagaagttgt agtttcgatt tgagacttga taaccgcaac acggtgagaa atcgcttcag
     1861 gatttcctgc accttctaca ataaccgtgc tatctttgtc cacggtcact ctcgctgctt
     1921 gaccaagagc ttcaattgtc gcatctttca actcaagacc aaggtcttct gtgataactg
     1981 ttccgcctgt taagatggcg atatcttcaa gcatggcttt gcgacggtca ccaaaaccag
     2041 gtgccttgac tgctactacg ttgaaggttc cacgaatctt gttcaaaaca agagttggaa
     2101 gagcctcgcc atccacatca tccgcaataa tcaagagtgg acgattgctt tggagaatgc
     2161 tttccaaaag tggcaagatt tcttggatat tggaaatttt cttgtctgta atcaaaatgt
     2221 acggattttc aaggtcagcc accatttttt cgctatcagt caccatgtac tgtgaaaggt
     2281 aaccacggtc aaactgcatt ccttctacga cttcaagctc tgtttccata ccacgtgact
     2341 cttcgatggt gatgacaccg tctttgccaa ctttttccat tgcttcagag atgtactcac
     2401 caactttttc agaacgagaa gatacggctg caacttgagc aatagcttct ttattggcaa
     2461 cagggatggc gttgtttttc aaagcttcaa ctgctgcggc aaccgctgtt tcaatcccac
     2521 gacgaatacc gattggattt gcacctgctg tgacgttttt gattccttca cggacgatag
     2581 cttgggtcaa gactgttgca gtcgtagtcc cgtcacctgc gatatcattg gttttagaag
     2641 ctacttctga tactaactta gcacccatat tttcaaaatg gtcttccaat tcgatttctt
     2701 tggcaatggt cacaccgtca ttggtaatca agggtgaacc gaatgacttt tcaagaacga
     2761 cattgcgacc ttttggtccc aaggttactt taacagtgtc tgcaaggata tcgacaccac
     2821 gaaccatggc tgaacgggca tctgatgaaa atttaatttc ttttgacata cttactttct
     2881 ccttctattc ctcaatgatt gccaaaatgt tagcttcgcc tacgatgatg tacttttcat
     2941 cgccatcttt gacatcaaga cctgcgtggg cttcaactaa gacacgatct ccagttttaa
     3001 cacttggagc aaccaagtca ccgttcaagg tacgaacacc ttgtccagta gccacaactt
     3061 gagctgtttt ggttttttct tgggctgagc ctgcaaggac aaagccccca acggtttgtt
     3121 ctttttcttc tatttttaag accacacggt cccctaatgg tttcaacatc tgatttcctc
     3181 cataatgaga tagatattat tagcactctt tgaacttgag tgctaattca taattctatt
     3241 gtatcacttg gtcagaaata gtcaagaaaa aagtctgact ttctcaagat aaaaagcctg
     3301 agaccaactc agacttttta atgtttatac tcaatgaaaa tcaaagagca aactaggaag
     3361 ctagccgcag gctgctcaaa gcattgcttt gatgttgtgg ataaagctaa cgtggtttga
     3421 agagattttc gaagagtatt aaaatggcaa ttcttcctct tccaagacta aatctgccaa
     3481 atcttggcct gcattatttt cacgcatggc acgttgagca cgactttcca agagttggaa
     3541 tcctgtgaca agtacttcgg tcacgtagtt catttggcca tttttctcaa agcgacgggt
     3601 acgcaattct ccatcaacgg aaatgagact acctttggtt gcgtagcttg ccaaagtttc
     3661 tgctagtctg ccccatagga ccatattgac aaaatcagct tcacgttcac cgttttggtc
     3721 tttgtaacga cggttcacag cgatagttgc tcgcgctacc gacttgtcat tgttggtttt
     3781 gtgcaattct ggtgtagacg ttaaacgccc aatcatgata actttattat acatattttc
     3841 ttcctcctac ttatctattc gtaggaaatc aaaaaagtta cagaaatttg taacttttcg
     3901 aggaaatttc ttatttttta tgaatcatga aacctgtcgc ctgttgattg gccataatgg
     3961 tcatatctgt aatctgaaca cggcgaggct gactggtcac atagactact gtgtctgcaa
     4021 tatcctgagc ttgcaaggct tctattcctt ggtaaacgga cgcagcccgc tctttatcac
     4081 catgaaaacg aacagttgag aaatctgttt cgacaatccc aggctgaatg gttgtcacct
     4141 tgatatccgt tgcgatggta tcaattcgca gtccatccga aaaggtctta accgcagcct
     4201 tggtagctga gtaaacagcg gcaccagcat aggcgtagat tcctgcggtt gaccccatat
     4261 tgataacgtg accttgattg acttttacca ttgctggcaa gaaacagcga gtaaccgcca
     4321 tcagaccttt aacattggta tccaacatgg tcaacatatc caactcctca tagtcttgat
     4381 agggagccaa gccaagagcc agtccggcgt tgttgaccaa gatatcaatc ctccctatcg
     4441 tttctagaat atcagagcaa acagtcttca ccatgaccat atccgtcaca tctagtggaa
     4501 aagtccagac ggtttgattt ggaaagctta ctgcaaactc cgacttgagg atttctaatc
     4561 tgtctatccg tcgtcctgtt agaacgacat cctcaccctg ctccagataa gcacgcgcaa
     4621 tcgcttcacc gattcctgag gttgctcccg taatcactac attttttgcc atcttatttc
     4681 cttctatcag atgctgacaa gttcctaggc agtccagtgt ttcgctgggt cgaacggtgt
     4741 tccgacaact tggtcttctg ataattcaag caccccacgt ttttgcggag catttggcaa
     4801 atgcaattca cgaggactac acatcatccc aaaactcttt tcaccacgaa gttcgcctgg
     4861 gaaaatgaaa ttcccttttg gcatcatggc accaggaaga gccacaatgg ttttcaaccc
     4921 aacacgcgca ttaggtgctc ctgcaacgat ttgcactatc ttgtcacttg cgactgcaac
     4981 ttggcagatg ttgaggtggt cactgtctgg atgagctacc atctcgacaa tttcaccaac
     5041 aacaaactta ggttccttat cattaacaat ttcttctgta aaaccttccg cctgtaattc
     5101 ttggttcaaa cgagcgactt gctcatctga taaaaagact tgaccgcgct ctgcaatttc
     5161 aaacaagctc gaaacctcaa aaatgttcca agctactgtt tccccatttt ctttgaggaa
     5221 aacacgggct accttgcctt tgcgttccac attcagtttg gcatctccgc tatttttcac
     5281 gatgaccata aggacatcac cgacatgttc tttgttatac gtaaaaatca ttgtttcctt
     5341 tttctcctat ttcaatcctg ctaaaaaatc gttaatttgc tccttacttt tacggtcgcg
     5401 attgacaaaa cgaccaattt ccttgtcctt ttctagaaca acaaggctag gaattccgta
     5461 aacatcccag agtttggcca aatccatata ctgatctcgg tccattcgaa taaaggtgaa
     5521 ctctggattg gtctcctcaa tctctggtaa ggcaggataa atataacgac aatcgccaca
     5581 ccagtctgcc acaaaaagga agaccttctt gcccgctttt tccactaaag atgctaattc
     5641 ttctaaactt gctggctgta tcataagact tcctcctcat agactaggtc ttcattttca
     5701 tagacaaagg tataatgacg gccatcctca aaaataacgc caccaaccaa gctctccaga
     5761 ctgctttcgt aaacttgaac atagagggtc gcaattgccc ccatgtcgga aaaatggtct
     5821 cgcacaatct ctgtcaactc ttcctgagtc ttcatgagct tacggtcatc tgcaactttt
     5881 ttcgtagcaa gagcaaggct tccgatacct agcagagcca agcctgccat ccacattttt
     5941 ttagctttca taccattcat tttaacacaa aaaaggcttc aggacaaatg aggaagcagc
     6001 agaaaagcaa gtaaaaagcc tcttccttta aggaaaagga cttcttatac taagagcaaa
     6061 ctaggaagct agccgcaggc tgctcaaaac acggttttga ggttgtagat aaggcgacgc
     6121 tgacgtggtt tgaagagatt ttcaaagagt attattctta ttgccaggca cctaagttgc
     6181 caacgtagta accatcaggt gtgtaggtat tgcgaagcat cttacctgat gaagccagat
     6241 aatactactt gccattgtct ttgacccaat cattcgcaat catggaacca gaagaactca
     6301 cataatacca ttctcccttg tcataaaccc aagtactgac tttcatggtt cctgagcaat
     6361 taaaggcaaa aaaactgtcc aatatcattc gttttttaaa agcatttgac actacatcat
     6421 ctacgctgta gtacatagat acatcaaacg taaaagccaa aatatcgaaa aatatacaac
     6481 ttttaaaggc agcatttcat tttttaaagt ctaacaacca tagaactgaa atcagagcaa
     6541 ggcatcaatt tcctactctt agtacgtcta ttttgatggt ggaagtgaag atttttttat
     6601 ttaacgtaga caatttccaa cttcccaaaa gccacatctc cacggatagt caaggttttg
     6661 ctggttgggg ctacaggagc gtcagcctta gctgcaccaa aggaggtttc tactttcaaa
     6721 tctacacgcc agtgttgtgg aacatagacg gttgcatttc cgaaggccac ttcaatattt
     6781 aaagttgcaa aatcacctag catctctgca ttatcatagt agattttagc atccccaaaa
     6841 gcgacttcca cttggtcatc tacgagatct tgatcttgct tatagaaagt cccgctacca
     6901 aaagcgactt ccttatccgt gacgactgtt tttttcccat tgtaccacca ttttttttca
     6961 ttccagaact tacttgaatg cgtcagataa ccaacaccaa gtaccaccaa gatgctagcc
     7021 caaataagag aatgattggt aactggtaac aagtcataag cgtaatttgc aatgatgagc
     7081 gccagtaaac ctgtaaaaac tgccgaagtg agatgacgtc taaggatggc ctcaatggac
     7141 ttataagcaa aaaaaacaat acctagtaaa ggccatattt taccatccaa agaaggaatt
     7201 ccaaaattcc cttgcagcaa gatccaagct gctaaaacca ataaaacaat accaaatgct
     7261 ttctttttca tgttttttac ctcatgtttc ttagattttc ttttaggagg gattggtaat
     7321 gccgtgagac atgaacctcc ttgtgcgtct gataaaagga aatggtgccc gttcctgaaa
     7381 aggacttgtc cactgagtaa atctgacgga tgtttgcgat cgttgacttg gaaactcgat
     7441 taaaatagcg aggcaagata gactccaact catagagctt gaggcgaacc tcataagctt
     7501 ccttctggtt atgagcgtag atcttgctcc cttctgtttc aaagaagaga atttctgaca
     7561 ggtctagata atattcacct gtccccttgt aaaaagtcaa cctcggagcc tttgactctt
     7621 gcaagagccg ttgcaagtct gcaatttcat ctgtcaaagt gggggtcttg atgacaattt
     7681 cagtctcctc taaattgccg tcaatctcaa ttcgtaactt catcacatct cctttctgac
     7741 tctactatat caaagctaag ttaggaatac aagggcaaaa aagcaagtgg tcaatttgaa
     7801 gcagtaagtg gttgtaggac tagcttaact tacatgtcag aataggaaga aaaggaatcc
     7861 ccacaccaga ccacaagcat agccaaccaa gacatccttg ggataatgaa caccccctaa
     7921 aaccctcacc aaccccagca aagctgaaaa gatcaagcat actaagccaa taggtagact
     7981 agcatgcaga caggccatgg agatgatagt tgcagaaaag acatggcgac tgggcatcga
     8041 ccgtcccgaa ctatccttat caagaagggg acagatatcc caagtttcat aaggtctcgg
     8101 gtgattgatt ttcttacgaa acagggacaa ggccacaaaa cctgatgcag gaataagcac
     8161 ataaacccca acttgctgac caagtcctag ttgcaggtaa gtggtgacta gcaagatcag
     8221 atagaccagg ggcatggcga ctgtcatcaa acgattgaaa ctgcgtaata ggaataaaag
     8281 aattggacga ctagttagtc tggagctgat atttcgatac cattcttgat aatttttcat
     8341 ttatgcttct catacttttc tagaacttgt tgggatgttt tccccttggc aagccaatcc
     8401 actagcttgt ccaagcgacg tatttcctgc atcagagaat catcaatttc ctcaatacgg
     8461 acaccgcaaa tcttccctgt aattgcaatt cgttcaggga cataatatgg tgcttgtcga
     8521 aaaaaatctc cgtaagtaac atccctatcc agacaagcaa gaacgtcact cacttcatac
     8581 cctgtcaacc aactggtcac ttggtgaact gactctgcct ttccaccctt tcgctcaact
     8641 tttgcaatca aggctaagta gacagcagca aatttcatat tgtataattt ctgactcata
     8701 cttctctctt tctatgtgta ctagtataaa taagaaaaag aaggccgtca agccttcttt
     8761 tgatttattc ttctgcttca tcttctgtaa attgactatt gtacaagtca gcgtagaatc
     8821 caccttgcac catcaggtga atttgatgac caaaacgctt aaagactaac atcggtttac
     8881 ccataatctc ccccttctaa ataaaaatag ttctctggag aataattaaa tttctatgag
     8941 aactattttc ttgattaaaa aaatcccaag tgattttctc acttaggatc atgttctata
     9001 ggttaaatta aaacccatct acgttcgtat aaatcttttg gacgtcttcg tcgtcttcaa
     9061 gaacgctgta aagtttttca aaggtttcaa ggtcttcgcc tgacaattcc acttctgact
     9121 gaggaatcat ttccaattca gtcacttgga attcttcaat accagactca cggagagcaa
     9181 cgatagcctt gtgaaggtca gttggcgctg tgtaaactgt gattgtacct tcttgtgctt
     9241 ctacgtcatc cacatccaca tccgcttcga gcaattgctc aaagactgcg tccgcatctt
     9301 cacctccaaa tacaataaca cctttgttgt caaaaaggta agaaacagaa cctgaagcgc
     9361 ccatgtttcc gccgttttta ccaaaggctg cacggacatt ggctgctgta cggttaacgt
     9421 tagaagtcaa agtatccaca attagcatag agccatttgg cccaaaacct tcgtaacgtc
     9481 cttctgtaaa ggtttcgtct gtgtttcctt tggctttatc aatcgcttta tcgataatgt
     9541 gttttggcac ttgggcttgt ttagcacggt cgataacgaa tttcaaagct gagtttgatt
     9601 ctggatctgg atcacctttt ttagctgcta catagatttc tacaccaaat tttgcatata
     9661 ctttagagtt agctccatct ttagccgttt tcttggctac gatattggcc catttacgtc
     9721 ccattaggaa tctccttttt tcacatttta atctttctta ttataacaca agtttttttg
     9781 attttcacta gaggaaatgg attttattag caaatcaagc taggatagca ctttacctgc
     9841 taagatggtc ttgcctttct atctttatca acagacactc atccacattc aaaaaacaaa
     9901 ctagaccatt atctgcaaat agaaagtttc agccaagttt gacaaagtca gctcaaatta
     9961 ctgtttgaag tttgtagata taagcgacaa aaacaatcat actgcacctt ttgttgacag
    10021 tctactccag acatatcata gttcaagtaa atactttgaa attcaacagt tcttataggc
    10081 gctattgtat tctaagaaat caatagaaga gtttctaagc aaacctctaa tactcaataa
    10141 aaatcaaaga gcaaactaga aagctagcct caggttgctc aaaacactgt tttgaggttg
    10201 cggatggggc tgacatggtt tgaagagatt ttcgaagagt ataatttacg tgttcccaag
    10261 atggagaagt tagactagta cactggcact tctaaaacat tgctagcaat tgatttgttc
    10321 atatttaatt tcattttttc cataaatggg tattagatat aaacagcaaa atatttccga
    10381 tacgtgtcgt tcttgaattt ccaatcatct aaaacaagta aaggataatc aatcccctgt
    10441 atatcaagga attggctacc ctttttactt ttttacacat tctgtttgat agattcattt
    10501 taacatcacg agcatactcc aatggaaatc gctaggcaag agataaactt tcagatatcc
    10561 gcagagagat catcgcctct ttttgtcgca agcattctcc tctcctagtc attttctacc
    10621 ttatcttcta cctgaggata gagagttgtt ccccaaatag aaatcgtccg cttacgcact
    10681 agtggcaaat cggttttttc ataaaccgta cgccaccatt cccaggcaag cccggtacac
    10741 tctctaattt tgacagagag attacgaaca ttccctttta aaggaatact agtggtaaag
    10801 tgagccgtta aatcctgccc atttctgtcc caagccttag gagtcaagac ttccttacct
    10861 tgatgatcat aggataattc attccaagta atataatatt gggcaacata ggcaccacta
    10921 tgatccagca gtaaatctcc gtttctgtaa gctgtaacct tagtctcaac atagtctgta
    10981 ctattttgaa aggtcgcaac tacattgtca cgtaaaaaag aagttgtata ggaaatcggc
    11041 aagcctggat gatctgctgt aaagcgactg ccttcttgaa tcaagtcctc taccatatcc
    11101 accttgcctg ttacaactcg ggcacccgaa cttgggtcgc cccctaaaat aaccgccttc
    11161 acttctgtat tgtccaaaat ctgcttccac tctgtctgag gagctacctt gactcctttt
    11221 atcaaagctt caaaagcagc ctctacttca tcactcttac tcgtggtttc caacttgaga
    11281 tagacttggc gcccataagc aacactcgaa atatagacca aaggacgctc tgcagaaatt
    11341 cctctctgtt ttaaatcctc taccgttaca gtatcttgaa acacatctcc tggattttta
    11401 acagcgtcta cgctgactgt ataataaatc tgcttaaaat taacaatctg aatctgcttt
    11461 tcgcctgaat ggacagagtt aaaatcaata tcaagagaat tccctgtctt ttcaaagtca
    11521 gaaccaaact tgaccttgag ttgttccatg ctgtgagccg tgattttttc atactgcatt
    11581 ctagctggga cattattgac ctgaccataa tcttgatgcc acttagccaa caaatcgttt
    11641 accgctccgc gaacacttga attgctggga tcttccactt ggagaaagct atcgctactt
    11701 gccaaaccag gcaaatcaat actataagtc atcggagcac gatcgaccgc aagaagagtg
    11761 ggattattct ctaacaaggt ctcatccact acgagaagtg ctccaggata gaggcgactg
    11821 tcgttggtag ctgttacaga aatatcactt gtatttgtcg acaagctccg cttctttctt
    11881 tcgataacaa caaactcatc gggtagctga ttaccctctt tgatgaaacg attttcaata
    11941 ctttctccct gatgggtcaa gagtttcttt ttatcgtaat tcatagctag tataaagtca
    12001 tttactgctt tatttgccat cttctacctc ctaataagtt cctggattga gttgcataaa
    12061 ctcagacttg ttcagcgaaa tcagccgtgg ttggactaag tgatccaaaa tttcctcgta
    12121 caattcttct gagacattgc gtcgccgtct ggctagataa gaagtcggaa taaccgtatt
    12181 atccaacata aataccttat ctaagtcaat caaggttggt cttgtaaaag gattacgagc
    12241 tagatccggc tcttctatca taaagttctt gaccaaacgt ctggtcaaga gagctggttt
    12301 gaaggtctga tttttaacca actctttgtt tttagtcatg ctgttgtcaa tacagatata
    12361 catatgattc ttcacagcca aatcgctact aatagtcgga aaaggcaaat aaagagctac
    12421 aacatctcct ctcttaatca agcaagagca cccccttttc tcctaatgta acatagacag
    12481 gattgaccaa gtcttctgat tgactcagaa tttccaaagt ttgagtttgg cgcgctgtca
    12541 atttagtagc atcttgtctc ttcaatacaa aatgcttgtc gccaataacc ttgacaatat
    12601 aatccttctc caaagctgac tggtaaatcc acatcagatg ttgtctgtcc tgagaactca
    12661 agcgagaagg attttcaagc ctcccgatag tctgataaaa atcaaaaaca ggagctaact
    12721 cctgccaatc tgattggcta gttgtcaagg ctagaaaaag ggctttgcga gctgatactt
    12781 cttggttagc cttgagagtt actttcccct ccaagttttt tagaaatcgg gaaactccag
    12841 aaagcaaatt tttctctaac tgcgagaaat aaaaaccttt cgttcccaga cataagtctt
    12901 tcatgtcgct ttctctagca aataagagct caaacatttg atagtaaaag aaaaatatct
    12961 ggcactgggt cgcgctcatc ttttccttat cggcttcttt ttttaaccag agcaagggcg
    13021 acaggtagct ggattgagac atttcctcta cctcctactc ttttttaact ggagcatctg
    13081 cactagctgc cacttctttt gactggatac tttcccactg gttaatctcc tctgagataa
    13141 gaccttcgca tgtcttgaca aatagggcaa aagccttggt ctttcctgca tatttctccg
    13201 tttggcattg atagaggaat ttttctttct ccaggagttg cgcagttttt tggtaagaaa
    13261 tccaattttc ctttgcatta tacaaattga taatcccctc acacagcaag ccgagactgg
    13321 ataaggcaac cgaaatcaaa cggtagcgat cacctggcat aggaatagca caaaagacag
    13381 ctatgaggaa acctgccacg atttctgtta tttttaatac cttatagcgt ctacgatgtt
    13441 gaacgctttt ctttaaaaaa tgagctatct gtacgtctaa tcgctctgtc aggtacattt
    13501 cttctggcgt catattcgta actcctttca tttactttga taaccatagt ataacatatt
    13561 tgaatatcaa agtatagtaa aaactggact ataacttatt agacttcctg cgaaacaaaa
    13621 tatggtatag tagttctatg aattatgaag caagtaaaca actaactgat gcacgattta
    13681 agcgtcttgt tagtgttcag cgtaccactt ttgaagagat gttagctgta ttaaaaacag
    13741 cttatcaaaa aagtcggaca agctggtaaa atcttggctg acagtggtta tcaagggctc
    13801 atgaagatat atcctcaagc acaaactcca cgtaaatcca gcaaactcaa gccgctaaca
    13861 gttgaagata aagcctataa ccatgcgcta tctaaggaga gaagcaaggt tgagaacatc
    13921 tttgccaaag tagaaatgtt taaaatgttt tcaacaacct atcgaaatca tcgtaaacgc
    13981 ttcggattac
//
LOCUS       DAVKBC010000043        13816 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVKBC010000043 DAVKBC010000000
VERSION     DAVKBC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13816
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.043"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(172..1533)
                     /gene="dnaA"
                     /locus_tag="VWX64_001645"
     CDS             complement(172..1533)
                     /gene="dnaA"
                     /locus_tag="VWX64_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU9191080.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(1746..2504)
                     /locus_tag="VWX64_001646"
     CDS             complement(1746..2504)
                     /locus_tag="VWX64_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU9191081.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(2562..3743)
                     /locus_tag="VWX64_001647"
     CDS             complement(2562..3743)
                     /locus_tag="VWX64_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU9191082.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            3926..4405
                     /gene="rlmH"
                     /locus_tag="VWX64_001648"
     CDS             3926..4405
                     /gene="rlmH"
                     /locus_tag="VWX64_001648"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU9191083.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4449..4522
                     /locus_tag="VWX64_001649"
     tRNA            4449..4522
                     /locus_tag="VWX64_001649"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4483..4485,aa:Arg,seq:tct)
     gene            4688..4813
                     /gene="comC"
                     /locus_tag="VWX64_001650"
     CDS             4688..4813
                     /gene="comC"
                     /locus_tag="VWX64_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU9191084.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            4834..6159
                     /locus_tag="VWX64_001651"
     CDS             4834..6159
                     /locus_tag="VWX64_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9191085.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIATFLFPLGLYSYFRWIKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            6156..6935
                     /locus_tag="VWX64_001652"
     CDS             6156..6935
                     /locus_tag="VWX64_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9191086.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQKRLTISKKLI"
     gene            6960..7031
                     /locus_tag="VWX64_001653"
     tRNA            6960..7031
                     /locus_tag="VWX64_001653"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6993..6995,aa:Glu,seq:ttc)
     gene            7037..7110
                     /locus_tag="VWX64_001654"
     tRNA            7037..7110
                     /locus_tag="VWX64_001654"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7071..7073,aa:Asn,seq:gtt)
     gene            complement(7151..7693)
                     /locus_tag="VWX64_001655"
     CDS             complement(7151..7693)
                     /locus_tag="VWX64_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU9191087.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            7872..8639
                     /locus_tag="VWX64_001656"
     CDS             7872..8639
                     /locus_tag="VWX64_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEU9191088.1"
                     /translation="MIGISLIPALYNIIFLSSMWEPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDQLVSGSNTLTQKSSRLTAGVG"
     gene            8724..9062
                     /locus_tag="VWX64_001657"
     CDS             8724..9062
                     /locus_tag="VWX64_001657"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191089.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKS"
     gene            9090..9404
                     /locus_tag="VWX64_001658"
     CDS             9090..9404
                     /locus_tag="VWX64_001658"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU9191090.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(9505..12057)
                     /locus_tag="VWX64_001659"
     CDS             complement(9505..12057)
                     /locus_tag="VWX64_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU9191091.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDIALRNILHGNSSLVYTFTSGLGLNFYALSSYYLGSFLSPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGITKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(12119..13741)
                     /locus_tag="VWX64_001660"
     CDS             complement(12119..13741)
                     /locus_tag="VWX64_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9191092.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIHSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
BASE COUNT         4474 a         2213 c         2510 g         4619 t
ORIGIN      
        1 aaaaatgaat catggattct cctttattta tttttagtat tagaaagata atagtaataa
       61 tagagtctgt gaaatctgtg gaaaacagcc tttaaacaag tcatatcaag ttttttagct
      121 tgtttaaaaa atgtggataa aaaagataaa aaactaaaag ttatccacaa attatttgat
      181 tttctttttg attgattcaa tttctaaacg taaattatcg tcttgatcaa tcaaagattt
      241 tattttggca tgggcatgaa tgactgtggt atgatctttt cccccaaatt ccttcccaat
      301 ttttggaaga ctattatctg ttagttctct agataaatac atggctactt gacgggccaa
      361 aacaatattt tgaaggcgtc tacttccctt catttctttg atactaacac cataaaagtt
      421 accaacttca gtttggattt tatcaattgg gatgacgagc atttggctaa catcttgttt
      481 gcgggctcta atggcttctg cagcaatatc aatagtgata tccttgattt tttttactct
      541 ggcaattaaa gtgatgtcgt tgatggctcc ctcaagatct cgaacatttg aatcaaattg
      601 cccagctagg tattctagag tatcactttg gaaattgtag cctaaatgtt ccgtcttact
      661 ttgtaaaatg gcaatacgtg tttcaaagtc agggggtgtg atagtttgtg tcaatcccca
      721 actaaaacgc gtgacaagcc tctcctcgag cccttctaga tgttttggac tacgatcact
      781 cgttaggaca atctgttttt gcttgtcatg aagggcgtta aaggtattga aaaattcttc
      841 ctgagttgcg actttttttc cgctgagtga ctgtatatca tcgattaaca aaagatcaag
      901 actacgatag gtctttttaa acttttccat ttccccaagt cttaggtgat caagaaagtc
      961 attaataaag ctttcggcag ggatatattt aacacgcgca ttaggaatat tttttagaat
     1021 ttcatttcca atagcgttta ataagtgagt cttaccaagg cctggtcctc catagataaa
     1081 aagagggtta taggtcagag ccaaatcttc agagacagct aaagcggctg atacagccca
     1141 aacatttcca tccccttgaa taaagttatc aaaggtatac ttttctttta atcccgtatc
     1201 tgaataagga atagatacta actttggact atagtcataa agagttaaat ttgtagcttc
     1261 ttcaacttgt gagctagtcg tatcttgagg tttggtgaaa atatagtggg gagttatttc
     1321 agcgtcataa atttcaaaac cagctactac aataatatct tttagttgtt tttcccagac
     1381 catttccatt tcagagcgag gtagaaatat agtggcaaca ttttcctcta ccttgatgag
     1441 ttcagcttga atagcataga aatcatacat ggatcgagtc agtctttctt gtgcaaattc
     1501 taatatacga ttccaaaatt gtttttcttt caatcctttc tcctccttta ctatttaaaa
     1561 gtttaatact agagatattt taccatagat agcaagaatt ttccacaagc tgtgaaaaat
     1621 aatccacaat gttaccaaac tttatccaca ggttggggat aaaagaagaa attattgatt
     1681 tattaagctt tttatcgaaa aacatagtgg ataaccttgt gagataaaaa aataaaagaa
     1741 cagccttatt tcaggctgtt gataattcta ctatattctt cttgatttga aaaagaaata
     1801 atgatttttc cactgtcttt tttagatagt ttaatttcta catctaatcc gagtagtttt
     1861 cttaactgtt tttcttcatt ttgtatgaaa tgattagttt tttgctgttt cttttgtttt
     1921 ttctctgtca gaagagtttc taacttcctt acagaaatat cttcttctat aatccgttga
     1981 aagaaatagt cttgttgttc cttatttaac ccaactaggg aacgcgcatg ggcttgtgat
     2041 agtttgccat tttctacttc tgagagaatc tgttctggca aggaaagtaa acgaatggag
     2101 ttgctgatat atggacgaga cttgcccatc ttatctgcaa tttcagcatg ggtgaatcct
     2161 ttctctacga gagattcata ggcgcgtgct tcttctattg ggtttaaatt ttctctctgt
     2221 aaattttcaa taatggactg gaccatcatc tcttggtctg aaatctgttt aacaacagct
     2281 gggatagacc gtagaccagc taaaagtgaa gcccgatagc gtctctctcc tgcaaggatt
     2341 tcataaccaa taacaggaga ttgacgaaca ataatcggtt gaatgacccc attttctttg
     2401 atagactgtg ctagttcatc tagcttttct ctatcaaatt cttttcgggg ttgataggga
     2461 tttttttgta tatctgtgat agaaatcatt tcaaattttt ccatgattct acactaacac
     2521 atcttttctc ttatgtaaag ctttctttac atagatgtca attaagattc taaatcacct
     2581 gaactcttgt taagtttgat agaggtagtt tcttctttcc cgttacgata gtaggttatc
     2641 ttaatggtgt ctccgataga atggttgtaa agagcacttt gtaagtctgt tgatgaagca
     2701 atctctttgt catctacttt tgtaattaca tcgtattttt caaggtgacc attggcaggc
     2761 atattacttt gtaccgaacg aacaattaca ccagatgtaa cattacttgg aatattgagt
     2821 cttctgatgt cgcttgtact cacattagat aaattaacca tctggattcc caaagctgga
     2881 cgcgtcactt ttccgttttt ttctaactgt tcaataatat tgatagcatc atttgcagga
     2941 attgcgaaac caagaccttc tacagatgtt cctccatttg tagcaatttt acttgaggta
     3001 attccgataa cctgcccttg aatattgatc agtgggccgc cagagttacc tgggttaata
     3061 gcagtatcag tttggatggc ttttgtagaa atagcttgtc catcttccga ttttaaggat
     3121 acatttctat tgagactgga tacgatacct tgagtgacag tatttgcata ttcagaacct
     3181 aacgggctac cgatggcaat agcagtttct cctacagtta acttactaga atcaccaaac
     3241 tcagctactg ttgtcacttt ttctgaagag attttgacga cagcaatatc agagaaagtg
     3301 tcagctccga caatttctcc aggtacttta gtcccatctg acaatcgaat atctactttg
     3361 ctggcgccat ttataacgtg attgttggtg acgatgtaag cttctttatc attcttttta
     3421 taaataactc cagatccttc actagagatt cgctgagaat ctgtgtcagt atcatcattg
     3481 ccaaatacgc tattttgtct gtttgccgaa taagtaataa cagaaacaac agcatctttt
     3541 actttgttaa cggcctgtgt tgttgaattt tcgttcttat aggcagtttg tgtaatagta
     3601 ctattgttgt tagagttgtt tacactactt ttttgagtta gttgagttat tgaaaaacta
     3661 cccaaggctc cactaaaaaa gctaatgacg ataacgacta ataattgaaa ccattttttg
     3721 taaaatgttt ttagatgttt catatttgcc tccatatgtt tgaattactg aaagtataaa
     3781 ctgactagct taattataac ttaaacacaa aagttttaca caaactgtgg ataactcttt
     3841 tgaaactgtg attttcttaa ttgaaatcta ttttttattt tgtgaataag atgtgaaaaa
     3901 atagagaata tgttagaata gagtcatgaa aattaaagtt gtaacagttg ggaaactgaa
     3961 agaaaagtat ttaaaagatg gtatcgcaga gtattcaaaa cgaatttcta gatttgctaa
     4021 gtttgaaatg attgagttat cagatgaaaa aacaccagat aaggccagtg aatcagaaaa
     4081 tcaaaagatt ttagaaatag aaggtcagag aattttatca aaaattgctg accgtgattt
     4141 cgttattgtg ttagccattg aagggaaaac tttcttctca gaagaattta gtaagcagtt
     4201 agaagaaact tctataaaag gattttctac tcttactttt attattgggg gaagtttagg
     4261 attgtcatca tctgtaaaaa atagagccaa tctttctgtc agttttggtc gcctaacctt
     4321 gcctcatcag ttaatgagac tagttcttgt tgaacaaatc tatcgcgctt ttacgattca
     4381 gcagggattc ccctaccata aatagagaat tgacttttaa ttgaattttt ggtagaataa
     4441 ttgtgttagg tctcatagct cagctggata gagcattcgc cttctaagcg aacggtcgca
     4501 ggttcgaatc ctgctgggat caatataata gcaaagctgg gaattttccc ggcttttttc
     4561 ttaaaaaagt acactttggg agaaaaaaat gacagttgag agaattttat ctaaaacgaa
     4621 attccatttt gtataatggt ttttgtaagt tagcttacaa gaaaaaaaca ttttaggaga
     4681 ttttattatg aaaaacacag ttaaattgga acagtttgta gctttgaagg aaaaagactt
     4741 acaaaagatt aaaggtgggg agatgaggct gtcaaaattc ttccgtgatt ttattttaca
     4801 aagaaaaaag taatgaaata aggggaaaga gtaatggatt tatttggatt tgggacagtt
     4861 attgttcatt ttttaattat tagtcacagc taccatttaa tttgtaaagg tcaaataaat
     4921 agaaaagaat tattcgtttt tggtgcttat acattactaa cagaaatagt atttgatttt
     4981 cccttatata ttctatattt agatgggtta gggattgcaa catttttatt tcctttgggc
     5041 ctatattcct attttcgatg gataaaacag tatgagaggg atagaggact attcctaagt
     5101 ttactactat ctcttttata tgagagcact cataactttc tgtccgtaac tttctcctct
     5161 ataacaggag ataattttgt tttacaatat catttcccat tctttttcgt tgtgacggtg
     5221 ttgacctatt ttgttacatt aaaaatcatt tattatttcc atttggaact agcctatttt
     5281 gacaaggact acctttatcc tttcttgaaa aaagtatttt ttgctttact attgctacat
     5341 attgtatctt tcgtttcaga tatggtaagt acgattaaac atttgaatag ttttggaagt
     5401 attttgtcat ctattgtctt tatctctctc cttttgacct tctttgcaat gaattctcat
     5461 aaagttcaaa tggagaaaga gattgctttg aagcagaaga aatttgaaca gaaacattta
     5521 cagaattaca cagatgaaat tgttggtctg tataatgaaa tccgtggttt tcgacatgat
     5581 tatgctggaa tgcttgtcag catgcagatg gcaattgaca gtggtaattt acaggaaatt
     5641 gacagaattt acaatgaagt tttagtcaaa gcaaatcata aattgcgttc agataagtac
     5701 acttactttg atttgaacaa catagaagac tcagctttac gaagtttggt tgctcagtca
     5761 attgtctatg ctcgaaataa tggtgtagag tttacactgg aagtaaaaga tacgattacc
     5821 aagcttccaa ttgaactatt ggatttggtt cgtatcatga gcgttttatt gaataatgct
     5881 gtcgaaggat cggctgatag ctataaaaag cagatggaag tagcagttat taagatggaa
     5941 actgaaacag ttattgtgat tcagaattca tgtaaaatga cgatgactcc ttcaggagat
     6001 ctatttgcct taggattctc cactaaggga agaaatcgcg gagtcggatt aaataatgtg
     6061 aaagaactac tagataagta caacaatatt attttagaaa cagagatgga aggcagtaca
     6121 tttagacaaa tcattagatt taagagggaa tttgaatgaa agttttaatt ttagaagatg
     6181 ttattgaaca tcaagtgaga ctagagagaa tattggatga aatttcgaaa gaatcgaata
     6241 ttccaatatc atacaagaca acgggaaaag tccgtgaatt tgaagaatac attgaaaatg
     6301 atgaagtaaa tcaactttat ttcctagata tcgatattca tggaattgag aaaaagggat
     6361 ttgaagtggc tcagctcatt cgtcattaca atccttacgc tattatcgtc tttatcacta
     6421 gtcgatcaga gtttgcgact ctaacctata aataccaggt atcagcccta gattttgttg
     6481 ataaggatat caatgatgag atgtttaaga agagaattga gcaaaatatc ttctacacga
     6541 agagtatgtt acttgaaaat gaagatgttg tagattattt cgactacaat tacaagggaa
     6601 atgatttaaa aattccttac catgatattt tgtatattga aacaacaggg gtctctcata
     6661 aattgcgcat tattggtaag aattttgcaa aagagtttta tggtaccatg acagatattc
     6721 aggaaaagga caaacatact cagcgatttt attctcctca caagtcattt ttggtaaata
     6781 taggcaatat cagagaaatt gatcgaaaaa acttagaaat tgttttctat gaagaccatc
     6841 gttgtcctat ttcaagatta aaaattagaa aattaaaaga tattttagag aaaaaatctc
     6901 aaaagagatt gacaattagc aagaaattga tataatggtt atatctgcta cagatagaag
     6961 gtccgttggt caaggggtta agacaccgcc ttttcacggc ggtaacacgg gttcgaatcc
     7021 cgtacggact attttatccg ccatagctca gttggtagta gcgcatgact gttaatcatg
     7081 atgtcgtagg ttcgagtcct actggcggag tatagataaa agggaacaca gctgtgttcc
     7141 tctttttgta tcaatttgta tcaccaagca ttttcataag gaagtctgtt atttcttgag
     7201 aactttcttt ttttccatgt gcaatccaag tttggcagac accaaaaagt gcatgagtta
     7261 gatagatgct actatattct aattcagtgg tatttagatt cagttgcata aatcgctttt
     7321 gtaaatctgt actgagcatg atatgaagtt tatttcgtaa gaaattttgg atttctttag
     7381 tcccattttc agaaagaagg gcagccagaa gtggttctga ctctagatat tcaaaaactt
     7441 ctaaaatagc gtctcttttg tgatgagcat gtttttgaaa aatatattca aatgtatgga
     7501 atagcttgct ttgatagtgc tcaatcatat catacttatc cttatagtga gtatagaagc
     7561 tggaacgact aattccggct ttttctacta atttgacagt agaaatttta tcaaatggct
     7621 gttccatcag taattgtacc atagcgtttt caatagttcg ctttgttttt aagcgtttgt
     7681 tactttcttg catatttcct ccttgtaaac aaattagact atatgtctaa aaatagattt
     7741 tttatcttgt aatttagatt ttttaatgta taatctatta tatcaaaatt ttagacaata
     7801 tgtttaaaaa aggagaaact atgtttaaag aatggaaagc aatttaaaaa aaaacaacct
     7861 ttattattgt catgatcggg atttctctta ttccagctct gtacaatatc atatttttgt
     7921 catcaatgtg ggagccatat gggcaattgt ctgacttacc tgtggcagtt gtaaataatg
     7981 ataaagaggc ttcctataat ggtaatacta tggcaatagg aaaagacatg gtgtccaatt
     8041 taaaagaaaa taaaaccttg gattttcatt ttgtagatga agaggaagga aagaagggat
     8101 tggaagatgg cgattactat atggtagtga ctttaccaag tgatttatct gaaaaaacaa
     8161 ctacattatc caatattcaa tcgacagcag cttatcaatc attgacaagt gagcaacaaa
     8221 ctgagataag tgattctgta tctcaaaatt caactgatag tattcaatcg gctcaatcaa
     8281 ttgtagcttt agtacaagat ttacagggaa gtttagaaaa cttacaaaat caatcttcta
     8341 atctttcgac tttaaaaaat caatctaatc aagtatcacc tattacttct acttctttga
     8401 taggattgtc aagtggatta acagagatac aaggagatgt tactagcaaa ttagttcctg
     8461 ccagtcagtc gattgcatca ggtgtaaacg catatactac aggtgttgat aaagtttctc
     8521 agggcgcaag tcaactaagt gaaaaaaatg ccaccttgac aggtagtttg gatcaactag
     8581 tttcaggctc aaacaccttg acacaaaaat cttctagatt aacagcagga gttggttaat
     8641 tacaatcagg atctgggcaa ttagcagaca aatccagtca gttactttca ggtgcttctc
     8701 cattagagaa tagagctaat aaattggcag atggatctgg gaaactagca gaaggtggaa
     8761 caaagttaac ttctggattg gaagatttac agacaggact tgcttcttta ggacaaggac
     8821 taggtaatgc tagtgatcaa ctcaaatcag tatcaacaga atctaaaaat gcagagattt
     8881 tgtcaaatcc actcaatctt tcaaaaacag acaatgatca agttcctgta aatggaatcg
     8941 caatagctcc ttatatgata tcagttgctc tttttgttgc agcaatatca acaaatatga
     9001 tatttgcgaa attgccttca ggacgtcatc cagagagccg ttgggcttgg ttgaaatctt
     9061 gagctgaaat aaatggtatt atagctgttt tggcaggaat tttggtatat ggaggagttc
     9121 agcttattgg tttaactgct aatcatgaga tgagaatatt tattctcatc atcctaacaa
     9181 gtttagtatt catgtctatg gtgaccactt tagcaacgtg gaatagccgt ataggagctt
     9241 ttttctcact tattttgctt ttactacagt tagcatcaag tgcaggtact tatccacttg
     9301 ctttgacaaa tgatttcttt agatctatta atccctggtt accaatgagc tattcagttt
     9361 cgggattacg acaaacaatc tctatcaaca agtcattttc ctagctgtca tactagctct
     9421 atttactggt ttaggtatgc tagcctatca acataagaaa atggaagaag attaaaaaaa
     9481 tcgaccgatt aactggtcga ttttttatgc cttagatgac tttcgtctgt gattatagat
     9541 tccaaatagt aagagagaag taaaggaaca gattgctcca gtaataaaac cattgggaat
     9601 gaaggaaagt gtaatagttc ctttcccctt gggaatgtca actttcataa atccagtttg
     9661 agcttgttta atttctattt tcttaccatc ttggtaggca gaccaacctt tgtcataagg
     9721 aatggtgaag aaaatagatg tatcttgttg gacatcatat gtagcaaaaa ccttgttttt
     9781 agaagttgat actgtgacag gttgttcttt aattttttga attgcctcgg tgaaagtttt
     9841 ggtatctaaa cgatagaagg taggagattc aaatgatact tgtgaatttc cagggaaact
     9901 aacattgata ttgaaagttt ttttctcttt agtatatcct agattaaaga aggagaagac
     9961 attatcagtt gtaaaagtct ttttttcacc atttacaagg atgtcaacct tcttttgttt
    10021 atcgttagaa aagtgaaggt ttatgaaaga gagataaact tggctgtttt ctggaacttc
    10081 aatttgatac tggattgctg catcttcatt tgaagaactt gtgacactaa tcaaatcatt
    10141 agtattttct attttttctg ttttttcata aggtattgga gaaaaataat caaaattgac
    10201 gttagcaagt tgatttaaaa atgaggcctg attatccaag gtatgttcat tgaacttgac
    10261 atcattgtaa acagattgac tagcaactgc aatcggaaga gagtattgat tttcatatag
    10321 ggtaagatta tctttttgat agatatcttt aaaaccatac ttatcaatag gactgtctga
    10381 gatattgtac tggataccaa ataaactatc agccaaaata ctattatttg catatcggag
    10441 attgagatta gtcccagagg atttaaaacc aagtttatct aaagtagagc ttgatgaacg
    10501 atttcgaaca gatgaaaatt gagagattcc attgtagttg aatttcatac tgtcatttcc
    10561 tgtctgagtt tgtagttttt cagtacgagt aaattgattt ccaatatatg ttgagaaaga
    10621 ttccatagct gggatatctc gactataagc acttcgagaa gcaaatcccc attccttagt
    10681 aattccgtcc atttgagatg aagcatttaa actcatttca accagtataa ataaagagat
    10741 tagaatggca aatagattca cagatataaa ctttttgata actgcaagga gtaaaagaga
    10801 atagacaacc aaaaattcaa gagtaagcag aatattcaaa tctgttaaaa aagaataatg
    10861 cgattttaga tagatggtag ctaaaaatcc tgttactaca agaaaaagcg aaactaaaaa
    10921 attccagact ttaagttctt tcagacgctt taagacttct gctgctgtgt aaattaacaa
    10981 ggtagagaaa atccaagcat agcgatgtaa aaacatgttt ggagtatgca tgccttgcca
    11041 aaataagtca agagcttcta tgtaaaagct tgcaattaga aatgcaaaga atattacata
    11101 tatgagtttc acgtgaaact taatagattt cagcgtaaaa aataaaatgg tcaaaataaa
    11161 gggaagtagt ccaacaaaaa tcattgggat ggccccatac tttgttgtgt caaaggaacc
    11221 aatgaattgc ttagcaaaga gatcaagata ccagctactt tcagtttgaa actttgtaac
    11281 ttcagtcaat ttttccccat gtgtctgtaa atcaaacaga gtgggaagag tcataatcaa
    11341 actagccata ccagctaaaa aggagataac tatgaaatca agaacagatg attttcgagt
    11401 cttaaagtcc cacgaaattt gacagagata ccagaaaata agaaacaata ctgtcatata
    11461 tccaaaataa taattttgaa taaataagat tgacagactt gtaaagtaca ataggagttt
    11521 cttttcagtt atcagtagat gtaaaccagt tataattaaa ggaatcaaga taaaaacatc
    11581 tagccaggtt tttatctcta attgactgac agtgaaactc atcagagcat aggaagtaga
    11641 taaggctagt tttaaagtct gagggataga ttgaaacaat ttattcaaac taaaaaaggt
    11701 tgacagacca atcaatccaa attttaagag agttgtcaga tagatagcat ctggcatatt
    11761 cgttagatca aaaaagtaaa ccagaggtga gagaaaacta cccaagtaat aactagatag
    11821 agcatagaag tttagtccta gaccacttgt aaaggtgtaa accagactac tatttccatg
    11881 taggatattt cgtaaggcta tatcaaaaat aacgtattga tgaaagccat ctcctaatag
    11941 aggagagttg tcgctattcc agtagatacc ttgagataga tatactccag acataatcac
    12001 tacaggaatg atgaaagaaa taaaataggt tcgatatgtt tttaaaaatg atttcatgtt
    12061 acctcgtaga atgatagaaa actcagttgg ttaacccaac tgagttttga agttttattt
    12121 agtctttcca aagttcttta acttttgctt gtacttctgc attttctagg aattcatcgt
    12181 aggtttcatc gatacggtca atgacgccat ttttagataa gacaatgata tggttagcca
    12241 aagtttgaat aaactcgtgg tcatggctgg caaagatgat tgattcttta aagtttttca
    12301 atccatcatt caagcttgag atagattcca agtccaagtg atttgttgga tcatcaagta
    12361 caaggacatt tgattttaag agcatgagtt ttgaaagcat gacacgaact ttttctcccc
    12421 ctgacaagac atttacaggt ttgttaactt catctccaga gaagagcata cggccgagga
    12481 agccacgtag gaaagtattg tcatcttctt ctttacttgc gaattgacgc aaccagtcaa
    12541 gaattgattc tcctcctgca aaatcagctg agttatcttt tggtaggtaa gattgactag
    12601 ttgtaactcc ccacttgaca gttccttcat agtcaatatc tcccatgatt gcacgaatta
    12661 atgcagtcgt ttgaatatca ttttgtccaa taagtgctgt cttatcatct ggacgcaaga
    12721 tgaaactaat attatccaag atagtttcac catcaatctt tacagttaga ttttctactg
    12781 tcaagagatc attaccaatc tcacgttccg ctttaaagtt gataaatgga tatttacgac
    12841 tagatggtac aatctcttct agctcaatct tatcaagcat tttcttacgt gatgttgcct
    12901 gccttgactt agaagcattg gcagagaaac gagcaacaaa ttcttgcaat tgtttaattt
    12961 tttcttctgc tttagcatta cggtctgcta gcaatttagc agcaagctca gaagattcct
    13021 tccagaagtc gtagtttccg acatagagtt tgatttttcc aaagtcaagg tcggccatgt
    13081 gagtacaaac tttgtttaag aagtgacggt cgtgggatac tacgataact gtgttatcaa
    13141 agtcaatcaa gaagtcttct aaccaagtaa tcgagtggat atccaaaccg ttagtaggct
    13201 cgtccaagag aagaacatct ggtttaccaa aaagtgcttt ggcgaggaga acctttactt
    13261 tttcaccgtt ggccaattcg ctcatgtttt ggtagtgtaa ttcttctgga atgtttaggt
    13321 tttgaagtag ttgagaggct tcactctctg cttcccaacc tccaagttcg gcaaattctc
    13381 cttcgagttc ggcagcacga accccgtcct cgtctgagaa atcttccttc atgtagatag
    13441 catctttctc tttcatgatg ctataaagtt tttcatttcc catgataacg acatcaatgg
    13501 cacgttcatc ttcgtagtca aagtgatttt gacgaagaac agagagacgt tcatctggac
    13561 caagagagat gtgaccagta gtaggttcga tatctccagc taaaattttt aaaaaggttg
    13621 attttccggc accattagca ccgattaatc cgtaagtatt tccttctgta aatttgatat
    13681 tgacatcatc aaaaagtttg cgatcactaa aacgtagtga aacatcagat actgtaagca
    13741 atatttttct cctatatgtg taatatattt attctactag aaaatacaga aatattcaaa
    13801 tttttatttg tcaatt
//
LOCUS       DAVKBC010000044        13704 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVKBC010000044 DAVKBC010000000
VERSION     DAVKBC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.044"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..1072
                     /gene="dnaN"
                     /locus_tag="VWX64_001661"
     CDS             <1..1072
                     /gene="dnaN"
                     /locus_tag="VWX64_001661"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU9191093.1"
                     /translation="SSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAG
                     LLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYP
                     RIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDS
                     HRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIEAVEIFFANNQILFRSENISF
                     YTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGV
                     VSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRP
                     FTLVPADTDEDFMQLITPVRTN"
     gene            1137..1331
                     /locus_tag="VWX64_001662"
     CDS             1137..1331
                     /locus_tag="VWX64_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU9191094.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1415..2530
                     /gene="ychF"
                     /locus_tag="VWX64_001663"
     CDS             1415..2530
                     /gene="ychF"
                     /locus_tag="VWX64_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU9191095.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2601..3170
                     /locus_tag="VWX64_001664"
     CDS             2601..3170
                     /locus_tag="VWX64_001664"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU9191096.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3171..6680
                     /gene="mfd"
                     /locus_tag="VWX64_001665"
     CDS             3171..6680
                     /gene="mfd"
                     /locus_tag="VWX64_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU9191097.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTKVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            6738..7004
                     /locus_tag="VWX64_001666"
     CDS             6738..7004
                     /locus_tag="VWX64_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU9191098.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            6997..7365
                     /locus_tag="VWX64_001667"
     CDS             6997..7365
                     /locus_tag="VWX64_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU9191099.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7485..8753
                     /locus_tag="VWX64_001668"
     CDS             7485..8753
                     /locus_tag="VWX64_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU9191100.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8750..10027
                     /gene="tilS"
                     /locus_tag="VWX64_001669"
     CDS             8750..10027
                     /gene="tilS"
                     /locus_tag="VWX64_001669"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU9191101.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10031..10573
                     /gene="hpt"
                     /locus_tag="VWX64_001670"
     CDS             10031..10573
                     /gene="hpt"
                     /locus_tag="VWX64_001670"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU9191102.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10589..12547
                     /gene="ftsH"
                     /locus_tag="VWX64_001671"
     CDS             10589..12547
                     /gene="ftsH"
                     /locus_tag="VWX64_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU9191103.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            12669..13148
                     /locus_tag="VWX64_001672"
     CDS             12669..13148
                     /locus_tag="VWX64_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU9191104.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRKYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            13242..13313
                     /locus_tag="VWX64_001673"
     tRNA            13242..13313
                     /locus_tag="VWX64_001673"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13275..13277,aa:Glu,seq:ttc)
     gene            13566..>13704
                     /locus_tag="VWX64_001674"
     rRNA            13566..>13704
                     /locus_tag="VWX64_001674"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         4734 a         2063 c         2839 g         4068 t
ORIGIN      
        1 tagttctaaa aatgccattc ctattttatc aacagtaaaa attgacgtga ccaatgaagg
       61 tattacttta attggttcaa atggtcaaat ttcaattgaa aattttattt ctcaaaaaaa
      121 tgaagatgct ggtttgttaa ttacttcttt aggttcgatc cttcttgaag cttctttctt
      181 tatcaatgta gtatctagtt tacctgatgt aactcttgat tttaaagaaa ttgaacaaaa
      241 tcaaattgtt ttaaccagtg gcaaatcaga aattacccta aaaggaaaag atagcgaaca
      301 atatccacga atccaagaaa tttcagcaag cactccttta atacttgaaa caaaattact
      361 caagaaaatt attaatgaaa cagcctttgc tgcaagtaca caagagagtc gtccgatttt
      421 aacaggtgtc cacttcgtat tgagtcaaca caaagagtta aaaacagttg caacagactc
      481 tcatcgccta agccagaaaa aattgactct tgaaaaaaat agtgatgatt ttgatgtcgt
      541 aattcctagc cgttctctac gcgaattttc agcggtattt acagatgata tcgaagctgt
      601 agagattttc tttgccaata accaaatcct ctttagaagc gaaaatatta gcttctatac
      661 tcgtctccta gaaggaaact atcctgatac agatcgcttg attccaacag actttaacac
      721 tactattact tttaatgtgg taaacttacg ccagtcaatg gagcgtgccc gtcttttatc
      781 aagtgcgact caaaatggta ctgtgaaact tgaaattaag gatggggttg ttagcgccca
      841 tgttcactct ccagaagttg gtaaagtaaa cgaagaaatc gatactgatc aggttactgg
      901 tgaagatttg accattagtt tcaacccaac ttacttgatt gattctctta aagctttaaa
      961 tagcgaaaag gtgaccatta gctttatctc agctgttcgt ccatttactc ttgtgccagc
     1021 agatactgac gaagacttca tgcagctcat tacaccagtt cgtacaaatt aagtgaaaga
     1081 ggttgagcct ggctcgcctc ttttatgata taatcgaaaa agaaaaggag agtagtatgt
     1141 atcaagttgg aaattttgtt gagatgaaaa aatcacacgc ttgtacaatc aagtcgactg
     1201 gtaaaaaggc taatcgttgg gaaattacac gtgtaggagc agatatcaaa ataaaatgca
     1261 gtaattgtga gcatgttgtc atgatggggc gatatgattt tgagcgaaaa atgaataaaa
     1321 ttattgactg agaaccctta gttagagggt tagcacttta tccctttttg tgttataata
     1381 ttagggattg aaatgaaaac ggagaatgag aaatatggct ttgacagcag gtatcgttgg
     1441 tttgccaaac gttggtaaat caacactatt taatgcaatt acaaaagcag gagcagaggc
     1501 agcaaactac ccatttgcga ctattgatcc aaatgttgga atggtggaag ttccagatga
     1561 acgcctacaa aaactaactg aaatgataac tcctaaaaag acagttccca caacatttga
     1621 atttacagat attgcaggga ttgtaaaagg agcttcaaaa ggagaagggc tagggaataa
     1681 attcttggcc aatattcgtg aagtagatgc gattgttcac gtagttcgtg cttttgatga
     1741 tgaaaatgta atgcgcgagc aaggacgtga agacgccttt gtagatccac ttgcagatat
     1801 tgatacaatt aatctggaat taattcttgc tgacttagaa tcagtgaaca aacgatatgc
     1861 gcgtgtagaa aagatggcac gtacgcaaaa agataaagaa tcagtagcag aattcaatgt
     1921 tcttcaaaag attaaaccag tcctagaaga cgggaaatca gctcgtacca ttgaatttac
     1981 agatgaggaa caaaaggttg tcaaaggtct tttccttttg acgactaaac cagttcttta
     2041 tgtagctaat gtggacgagg atgtggtttc agaacctgac tctatcgact atgtcaaaca
     2101 aattcgtgaa tttgcagcga cagaaaatgc tgaagtagtc gttatttctg cgcgtgctga
     2161 ggaagaaatt tctgaattgg atgatgaaga taaaaaagag tttcttgaag ccattggttt
     2221 gacagaatca ggtgtagata agttgacgcg tgcagcttac cacttgcttg gattgggaac
     2281 ttacttcaca gctggtgaaa aagaagttcg cgcttggact ttcaaacgtg gtatgaaggc
     2341 tcctcaagca gctggtatta tccactcaga ctttgaaaaa ggctttattc gtgcagtaac
     2401 catgtcatat gaagatctag tgaaatacgg atctgaaaag gccgtaaaag aagctggacg
     2461 cttgcgtgaa gaaggaaaag aatatatcgt tcaagatggc gatatcatgg aattccgctt
     2521 taatgtctaa aaattaataa atggtgtcaa ttaggttgga aaaaaattcc aacccttttg
     2581 gcttttgaaa ggaaaaataa atgaccaaat tacttgtagg cttgggaaat ccaggggata
     2641 aatattttga aacaaaacac aatgttggtt ttatgttgat tgatcaacta gcgaagaaac
     2701 agaatgtcac ttttacacac gataagatat ttcaagctga cctagcatcc tttttcctaa
     2761 atggagaaaa aatttatctg gttaaaccaa cgacctttat gaatgaaagt ggaaaagcag
     2821 ttcatgcttt attaacttac tatggtttgg atattgacga tttacttatc atttacgatg
     2881 atcttgacat ggaagttggg aaaattcgtt taagagcaaa aggctcagca ggtggtcata
     2941 atggtatcaa gtctattatt caacatatag gaactcaggt ctttaaccgt gttaagattg
     3001 gaattggaag acctaaaaat ggtatgtcag ttgttcatca tgttttgagt aagtttgaca
     3061 gggatgatta tatcggtatt ttacagtctg ttgacaaagt tgacgattct gtaaactact
     3121 atttacaaga gaaaaatttt gagaaaacaa tgcagaggta taacggataa atggtgacct
     3181 tattagattt attctcagaa aatgatcaga ttaaaaaatg gcatcaaaat ttaacagata
     3241 agaaaagaca actaatactt ggtttatcaa catctactaa ggcgcttgca attgcaagca
     3301 gtttagaaaa agaagatagg attgtgttat tgacgtcaac ttatggagaa gcagaaggac
     3361 ttgttagtga tcttatatct atcttgggtg aggaactcgt ctatccattt ttggtagatg
     3421 atgctcctat ggtggagttt ttgatgtctt cacaggaaaa aattatttca cgggttgaag
     3481 ccttgcgttt tttgactgat tcatctaaga aagggatttt agtttgtaat atcgcagcaa
     3541 gtcgattaat tttaccgtct cccaatgcat tcaaagatag tattgtaaaa atctcagttg
     3601 gtgaagaata tgatcaacac gcgtttatcc atcagttaaa ggaaaatggc tatcgaaaag
     3661 ttactaaagt acaaactcag ggcgaattta gtcttcgagg agatatttta gatatttttg
     3721 aaatatccca gttagaacct tgtcgaattg agttttttgg tgatgaaatt gatggtatca
     3781 ggtcatttga agtagaaaca caattatcga aagaaaataa gacagaactc actatctttc
     3841 cagctagtga tatgcttttg agagaaaagg attatcaacg aggacagtca gctttagaaa
     3901 aacaaatttc aaaaacttta tcacctattt tgaaatcata cctagaagaa attctttcaa
     3961 gttttcacca aaaacaaagt catgcagact ctcggaagtt tttatctttg tgctatgata
     4021 agacatggac tgtctttgat tatattgaaa aagatactcc aatattcttt gatgattatc
     4081 aaaaattgat gaatcagtat gaagtctttg aaagagactt agcgcagtac tttacagaag
     4141 aattacagaa tagtaaagca ttttctgata tgcagtattt ttctgatatt gaacaaatct
     4201 ataaaaaaca aagtccagtg acctttttct ctaatcttca aaagggttta ggaaatctca
     4261 aatttgacaa aatttatcaa ttcaatcaat atcctatgca ggaatttttc aatcagtttt
     4321 cttttctaaa agaagaaatt gaacgatata aaaaaatgga ttacaccatt attctgcagt
     4381 ctagcaattc aatgggaagt aaaacattgg aggatatgtt agaggaatat cagattaaat
     4441 tggattctag agataagaca agtatctgta aagaatctgt aaacttaata gagggtaatc
     4501 tcagacatgg ttttcatttt gtagatgaaa agattttatt gataactgaa catgagattt
     4561 ttcaaaagaa attaaagcgt cgttttcgaa gacaacatgt ttcaaatgca gagagattaa
     4621 aagattacaa tgaacttgaa aaaggggact atgttgtcca tcatatccat gggattggtc
     4681 aatatctagg aattgaaacc attgaaatca agggaattca tcgcgattat gtcagtgtcc
     4741 aataccaaaa tggtgatcaa atttctatcc ccgtggaaca gattcatcta ctgtccaaat
     4801 atatttcaag tgatggtaaa gctccaaaac tcaataaatt aaatgacggt cattttaaaa
     4861 aggccaagca aaaggttaag aaccaggtag aggatatagc tgatgattta atcaaactct
     4921 actctgaacg tagtcagttg aagggttttg ctttctcagc tgatgatgat gatcaagatg
     4981 cctttgatga tgctttccct tatgttgaaa cggatgatca acttcgtagt attgaggaaa
     5041 tcaagaggga tatgcaggct tctcagccaa tggatcgact tttagttggg gatgttggtt
     5101 ttggaaagac tgaagttgct atgcgtgcag cctttaaagc agtcaatgat cacaaacagg
     5161 ttgtcattct agttccgacg acggttttag cgcaacagca ctatacgaat tttaaggaac
     5221 gattccaaaa ttttgcagtt aatgttgatg tgttgagtcg ctttagaagt aaaaaagagc
     5281 agactgcaac acttgaaaaa ttgaaaaacg gtcaagtcga tattttgatt ggaacacatc
     5341 gtgttttgtc aaaagatgtt gtgtttgctg atttgggctt gatgattatt gatgaggaac
     5401 agcgatttgg tgtcaagcat aaggaaactt tgaaagaact gaagaaacaa gtggatgtcc
     5461 taaccttgac cgctacgcca atccctcgta ccctccatat gtctatgctg ggaatcagag
     5521 atttgtctgt tattgaaact ccgccgacta atcgctatcc tgttcagacc tatgttttgg
     5581 aaaagaatga tagtgtcatt cgtgatgctg tcttgcgtga aatggagcgt ggaggtcaag
     5641 tttactatct ttacaacaaa gttgatacaa ttgttcagaa ggtttcagaa ttacaggagt
     5701 tgattccgga ggcttcgatt ggatatgttc atggtcgaat gagtgaagtc cagttggaaa
     5761 atactctatt agactttatt gagggacaat acgatatctt ggtgacgact actattattg
     5821 agacaggggt ggacattcca aatgctaata ctttatttat tgaaaatgcg gaccatatgg
     5881 gcttgtcaac cttatatcag ttaagaggaa gagtcggtcg tagtaatcgt attgcttatg
     5941 cttatctcat gtatcgtcca gaaaaatcaa tcagtgaagt ctctgaaaag agattagaag
     6001 cgattaaagg atttacagaa ttgggctctg gctttaagat tgcaatgcga gatctttcga
     6061 ttcgtggagc aggaaatctt ttaggaaaat cccagtctgg tttcattgat tctgttggtt
     6121 ttgaattgta ttcgcagtta ttagaggaag ctattgctaa acgaaacggt aatgctaacg
     6181 ctaacacaag aaccaaaggg aatgctgagt tgattttgca aattgatgcc tatcttcctg
     6241 atacttatat ttctgatcaa cgacataaga ttgaaattta caagaaaatt cgtcaaattg
     6301 acaaccgtgt caattatgaa gagttacaag aggagttgat agaccgtttt ggagaatacc
     6361 cagatgtagt agcctatctt ttagagattg gtttggttaa atcatacttg gacaaggtct
     6421 ttgttcaacg tgtggaaaga aaagataata aaattacaat tcaatttgaa aaagtcactc
     6481 aacgactgtt tttagctcaa gattatttta aagctttatc cgtaacgaac ttaaaagcag
     6541 gcatcgctga gaataaggga ttaatggagc ttgtatttga tgtccaaaat aagaaagatt
     6601 atgaaatttt agaaggtttg ctgatttttg gagaaagttt attagagata aaagagtcta
     6661 aggaagaaaa ttccatttga tatttttctt ctataaaata gataaaaatg gtacaataat
     6721 aaattgaggt aataaggatg agattagata aatatttaaa agtatcgcga attatcaagc
     6781 gtcgtacagt cgcaaaggaa gtagcagata aaggtagaat caaggttaat ggaatcttgg
     6841 ccaaaagttc aacggacttg aaagttaatg accaagttga aattcgcttt ggcaataagt
     6901 tgctgcttgt aaaagtacta gagatgaaag atagtacaaa aaaagaagat gcagcaggaa
     6961 tgtatgaaat tatcagtgaa acacgggtag aagaaaatgt ctaaaaatat tgtacaattg
     7021 aataattctt ttattcaaaa tgaataccaa cgtcgtcgct acctgatgaa agaacgacaa
     7081 aaacggaatc gttttatggg aggggtattg attttgatta tgctattatt tatcttgcca
     7141 acttttaatt tagcgcagag ttatcagcaa ttactccaaa gacgtcagca attagcagac
     7201 ttgcaaactc agtatcaaac tttgagtgat gaaaaggata aggagacagc atttgctacc
     7261 aagttgaaag atgaagatta tgctgctaaa tatacacgag cgaagtacta ttattctaag
     7321 tcgagggaaa aagtttatac gattcctgac ttgcttcaaa ggtgataaaa tggaaaattt
     7381 attagacgta atagagcaat ttttgagttt gtcagatgaa aagctggaag aattggctga
     7441 taaaaatcaa ttattgcgtt tacaagaaga aaaggaaagg aagaatgcgt aaattcttaa
     7501 ttattttgtt gctaccaagt tttttgacca tttcaaaagt cgttagcaca gaaaaagaag
     7561 tagtctatac ttcgaaagaa atttattacc tttcacaatc tgactttggt atttatttta
     7621 gagaaaaatt aagttctccc atggtttatg gagaggttcc tgtttatgcg aatgaagatt
     7681 tagtagtgga atctgggaaa ttgactccca aaacaagttt tcaaataacc gagtggcgct
     7741 taaataaaca aggaattcca gtatttaagc tatcaaatca tcaatttata gctgcggaca
     7801 aacgattttt atatgatcaa tcagaggtaa ctccaacaat aaaaaaagta tggttagaat
     7861 ctgactttaa actgtacaat agtccttatg atttaaaaga agtgaaatca tccttatcag
     7921 cttattcgca agtatcaatc gacaagacca tgtttgtaga aggaagagaa tttctacata
     7981 ttgatcaggc tggatgggta gctaaagaat caacttctga agaagataat cggatgagta
     8041 aagttcaaga aatgttatct gaaaaatatc agaaagattc tttctctatt tatgttaagc
     8101 aactgactac tggaaaagaa gctggtatca atcaagatga aaagatgtat gcagccagcg
     8161 ttttgaaact ctcttatctc tattatacgc aagaaaaaat aaatgagggt ctttatcagt
     8221 tagatacgac tgtaaaatac gtatctgcag tcaatgattt tccaggttct tataaaccag
     8281 agggaagtgg tagtcttcct aaaaaagaag ataataaaga atattcttta aaggatttaa
     8341 ttacgaaagt atcaaaagaa tctgataatg tagctcataa tctattggga tattacattt
     8401 caaaccaatc tgatgccaca ttcaaatcca agatgtctgc cattatggga gatgattggg
     8461 atccaaaaga aaaattgatt tcttctaaga tggccgggaa gtttatggaa gctatttata
     8521 atcaaaatgg atttgtgcta gagtctttga ctaaaacaga ttttgatagt cagcgaattg
     8581 ccaaaggtgt ttctgttaaa gtagctcata aaattggaga tgcggatgaa tttaagcatg
     8641 atacgggtgt tgtctatgca gattctccat ttattctttc tattttcact aagaattctg
     8701 attatgatac gatttctaag atagccaagg atgtttatga ggttctaaaa tgagggaacc
     8761 agatttttta aatcattttc tcaagaaggg atatttcaaa aagcatgcta aggcggttct
     8821 agctctttct ggtggattag attctatgtt tctatttaag gtattgtcta cttatcaaaa
     8881 agagttagag attgaattga ttctggctca tgtgaatcat aagcagagaa ttgaatcaga
     8941 ttgggaagaa aaggaattaa ggaagttggc tgctgaagca gagcttccta tttatatcag
     9001 caatttttca ggagaatttt cagaagcgcg tgcacgaaat tttcgttatg atttttttca
     9061 agaggttatg aaaaagacag gtgcgacagc tttagtcact gcccaccatg ctgatgatca
     9121 ggtggaaacg attttgatgc gcttgattcg aggaactcgc ttgcgctatc tatcaggaat
     9181 taaggagaag caagtagtcg gagagataga aatcattcgt cccttcttgc attttcagaa
     9241 aaaagacttt ccatcaattt ttcactttga agatacatca aatcaggaga atcattattt
     9301 tcgaaatcgt attcgaaact cttacttacc agaattggaa aaagaaaatc ctcgatttag
     9361 ggatgcaatc ttaggcattg gcaatgaaat tttagattat gatttggcaa tagctgaatt
     9421 atctaacaat attaatgtgg aagatttaca gcagttattt tcttactctg agtctacaca
     9481 aagagtttta cttcaaactt atctgaatcg ttttccagat ttgaatctta caaaagctca
     9541 gtttgctgaa gttcagcaga ttttaaaatc taaaagccag tatcgtcatc cgattaaaaa
     9601 tggctatgaa ttgataaaag agtaccaaca gtttcagatt tgtaaaatca gtccgcaggc
     9661 tgatgaaaag gaagatgaac ttgtgttaca ctatcaaaat caggtagctt atcaaggata
     9721 tttattttcc tttggacttc cattagaagg tgaattaatt caacaaatac ctgtttcacg
     9781 tgaaacatcc atacacattc gtcatcgaaa aacaggagat gttttgattc aaaatgggca
     9841 tagaaaaaaa ctcagacgtt tatttattga tttgaaaatc cctatggaaa agagaaactc
     9901 tgctcttatt attgagcaat ttggtgaaat tgtctcaatt ttgggaattg cgaccaataa
     9961 tttgagtaaa aaaacgaaaa atgatataat gaacactgta ctttatatag aaaaaataga
    10021 taggtaaaaa atgttagaaa acgatattaa aaaagtcctc gtttcacacg atgaaattac
    10081 agaagcagct aaaaaactag gtgctcaatt aactaaagac tatgcaggaa aaaatccaat
    10141 cttagttggg attttaaaag gatctattcc ttttatggct gaattggtca aacatattga
    10201 tacacatatt gaaatggact tcatgatggt ttctagctac catggtggaa cagcaagtag
    10261 tggtgttatc aatattaaac aagatgtgac tcaagatatc aaaggaagac atgttctatt
    10321 tgtagaagat atcattgata caggtcaaac tttgaagaat ttgcgagata tgtttaaaga
    10381 aagagaagca gcttctgtta aaattgcaac cttgttggat aaaccagaag gacgtgttgt
    10441 agaaattgag gcagactata cctgctttac tatcccaaat gagtttgtag taggttatgg
    10501 tttagactac aaagaaaatt atcgtaatct tccttatatt ggagtattga aagaggaagt
    10561 gtattcaaat tagaaagaat aatctttaat gaaaaaacaa aataatggtt taattaaaaa
    10621 tccttttcta tggttattat ttatcttttt ccttgtgaca ggattccagt atttctattc
    10681 tgggaataac tcaggaggaa gtcagcaaat caactatact gagttggtac aagaaattac
    10741 cgatggtaat gtaaaagaat taacttacca accaaatggt agtgttatcg aagtttctgg
    10801 tgtctataaa aatcctaaaa caagtaaaga aggaacaggt attcagtttt tcacgccatc
    10861 tgttactaag gtagagaaat ttaccagcac tattcttcct gcagatacta ccgtatcaga
    10921 attgcaaaaa cttgctactg accataaagc agaagtaact gttaagcatg aaagttcaag
    10981 tggtatatgg attaatctac tcgtatccat tgtgccattt ggaattctat tcttcttcct
    11041 attctctatg atgggaaata tgggaggagg caatggccgt aatccaatga gttttggacg
    11101 tagtaaggct aaagcagcaa ataaagaaga tattaaagta agattttcag atgttgctgg
    11161 agctgaggaa gaaaaacaag aactagttga agttgttgag ttcttaaaag atccaaaacg
    11221 attcacaaaa cttggagccc gtattccagc aggtgttctt ttggagggac ctccggggac
    11281 aggtaaaact ttgcttgcta aggcagtcgc tggagaagca ggtgttccat tctttagtat
    11341 ctcaggttct gactttgtag aaatgtttgt cggagttgga gctagtcgtg ttcgctctct
    11401 ttttgaggat gccaaaaaag cagcaccagc tatcatcttt atcgatgaaa ttgatgctgt
    11461 tggacgtcaa cgtggagtcg gtctcggcgg aggtaatgac gaacgtgaac aaaccttgaa
    11521 ccaacttttg attgagatgg atggttttga gggaaatgaa gggattatcg tcatcgctgc
    11581 gacaaaccgt tcagatgtac ttgatcctgc ccttttgcgt ccaggacgtt ttgatagaaa
    11641 agtattggtt ggccgtcctg atgttaaagg tcgtgaagca atcttgaaag ttcacgctaa
    11701 gaacaagcct ttagcagaag atgttgattt gaaattagtg gctcaacaaa ctccaggctt
    11761 tgttggtgct gatttagaga atgtcttgaa tgaagcagct ttagttgctg ctcgtcgcaa
    11821 taaatcgata attgatgctt cagatattga tgaagcagaa gatagagtta ttgctggacc
    11881 ttctaagaaa gataagacag tttcacaaaa agaacgagaa ttggttgctt accatgaggc
    11941 aggacatacc attgttggtc tagtcttgtc gaatgctcgc gttgtccata aggttacaat
    12001 tgtaccacgc ggccgtgcag gcggatacat gattgcactt cctaaagagg atcaaatgct
    12061 tctatctaaa gaagatatga aagagcaatt ggctggctta atgggtggac gtgtagctga
    12121 agaaattatc tttaatgtcc aaactacagg agcttcaaac gactttgaac aagcgacaca
    12181 aatggcgcgt gcaatggtta cagagtacgg tatgagtgaa aaacttggcc cagtacaata
    12241 tgaaggaaac catgctatgt ttggtgcaca gagtcctcaa aaatcaattt cagaacaaac
    12301 agcttatgaa attgatgaag aggttcgttc attattaaat gaggcacgaa ataaagctgc
    12361 tgaaattatt cagtcaaatc gtgaaactca caagttaatt gcagaagcat tattgaaata
    12421 cgaaacattg gatagtacac aaattaaagc tctttacgaa acaggaaaga tgcctgaagc
    12481 agtagaagag gaatctcatg cactatccta tgatgaagta aagtcaaaaa tgaatgacga
    12541 aaaataaccc tgagagaggc tggagcctct cttttttgtg cagtttagga gctaaaggga
    12601 acagaatgga taaaatggaa caaatgtgtt ttctaatctg ttagactgta tctagaaagg
    12661 ggaaaattat gattaaagaa ttgtatgaag aagtccaagg gactgtgtat aagtgtagaa
    12721 atgaatatta ccttcattta tgggaattgt cggattggga ccaagaaggc atgctctgct
    12781 tacatgaatt gattagtaga gaagaaggac tggcagacga tattccacgt ttaaggaaat
    12841 atttcaaaac caagtttcga aatcgaattt tagactatat ccgtaagcag gaaagtcaga
    12901 agcgtaaata cgataaagaa ccctatgaag aagtgggtga gctcagtcat cgtataagtg
    12961 agggaggtct ctggctagat gattattatc tctttcatga aacactaaga gattatagaa
    13021 acaaacaaag taaagagaaa caagaagaac tagaacgcgt cttaagcaat gaacgatttc
    13081 gagggcgtca aagagtatta agagacttac gcattgtgtt taaggagttt actatccgta
    13141 cccactagta agtcatgcaa aaaaaatgaa aaaaattaga aaaagtagtt gacaaagttt
    13201 gaaaagactg tataatagta agagttgaaa ataacaactc aggtccgttg gtcaaggggt
    13261 taagacaccg ccttttcacg gcggtaacac gggttcgaat cccgtacgga ctatggtatg
    13321 ttgcgtcagg accacttgat gaaaaaaagt ttaaaaaaac ttaaaaatct tcaaaaaagt
    13381 gttgacaagc gaaagcagtt gtgatatact aatatagttg tcgcttgaga gaagcaagtg
    13441 acaaagacct ttgaaaactg aacaagacga accaatgtgc agggcgctac aacataagtt
    13501 gtagtactga acaatgaaaa aaacaataaa tctgtcagtg acagaaatga gtaagaactc
    13561 aaacttttaa tgagagtttg atcctggctc aggacgaacg ctggcggcgt gcctaataca
    13621 tgcaagtaga acgctgaagg aggagcttgc ttctctggat gagttgcgaa cgggtgagta
    13681 acgcgtaggt aacctgcctg gtag
//
LOCUS       DAVKBC010000045        12906 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVKBC010000045 DAVKBC010000000
VERSION     DAVKBC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.045"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(55..585)
                     /locus_tag="VWX64_001675"
     CDS             complement(55..585)
                     /locus_tag="VWX64_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEU9191105.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPNWKMDLFSEEEKRNYFQTTCEIS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LYNIVNIVSDIHKLGI"
     gene            complement(579..1046)
                     /locus_tag="VWX64_001676"
                     /pseudo
     CDS             complement(579..1046)
                     /locus_tag="VWX64_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1596..2273
                     /locus_tag="VWX64_001677"
     CDS             1596..2273
                     /locus_tag="VWX64_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU9191106.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQVKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVETGEM
                     ELSARDTRFGPFLSREISPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2260..3057
                     /locus_tag="VWX64_001678"
     CDS             2260..3057
                     /locus_tag="VWX64_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU9191107.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3074..4177
                     /locus_tag="VWX64_001679"
     CDS             3074..4177
                     /locus_tag="VWX64_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU9191108.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            4184..4330
                     /locus_tag="VWX64_001680"
     CDS             4184..4330
                     /locus_tag="VWX64_001680"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191109.1"
                     /translation="MKIKEQTRKLAAGYSKRCFEVVDRTDEVSNHTHGKATLTWFELD
                     FRRV"
     gene            4433..5452
                     /gene="galE"
                     /locus_tag="VWX64_001681"
     CDS             4433..5452
                     /gene="galE"
                     /locus_tag="VWX64_001681"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9191110.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEELTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPYTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5454..6407
                     /locus_tag="VWX64_001682"
     CDS             5454..6407
                     /locus_tag="VWX64_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9191111.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(6469..6675)
                     /locus_tag="VWX64_001683"
     CDS             complement(6469..6675)
                     /locus_tag="VWX64_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU9191112.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            6727..7203
                     /locus_tag="VWX64_001684"
     CDS             6727..7203
                     /locus_tag="VWX64_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU9191113.1"
                     /translation="MAKEPWQEDIYDQEESRAERRPRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EGAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7212..7883
                     /locus_tag="VWX64_001685"
     CDS             7212..7883
                     /locus_tag="VWX64_001685"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU9191114.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHSISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVRKKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8014..8352
                     /locus_tag="VWX64_001686"
     CDS             8014..8352
                     /locus_tag="VWX64_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU9191115.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            8355..8984
                     /locus_tag="VWX64_001687"
     CDS             8355..8984
                     /locus_tag="VWX64_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU9191116.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9224..10375
                     /locus_tag="VWX64_001688"
     CDS             9224..10375
                     /locus_tag="VWX64_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9191117.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            10693..11442
                     /gene="truA"
                     /locus_tag="VWX64_001689"
     CDS             10693..11442
                     /gene="truA"
                     /locus_tag="VWX64_001689"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU9191118.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQVI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11432..12205
                     /locus_tag="VWX64_001690"
     CDS             11432..12205
                     /locus_tag="VWX64_001690"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9191119.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNDLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVSVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            12183..12644
                     /locus_tag="VWX64_001691"
     CDS             12183..12644
                     /locus_tag="VWX64_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9191120.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMIGMIVGFILSQSIKKIK"
BASE COUNT         3683 a         2397 c         2844 g         3982 t
ORIGIN      
        1 gggggcagta catttttggt atatataaaa tttgtaggag ctatatctac aattttatat
       61 tcccagttta tggatgtcac ttactatatt cacaatgtta tacagtgttt tttctctaat
      121 atttaaggag tgttctgttt ctcgaataaa ttcttcaaag tttaacccgt caacttgttc
      181 ctgaacaaga aaataatcat ccacgatata aaattcatca gttaaattag tagtataact
      241 tttatcggct aattttttta gcatgtgagc ttcatttttt atatcatcaa gagctgtcca
      301 ttctccttca gcatcataat tcacaaaagg tcttgactgc ttgatgatta ctttttgccc
      361 gtccgatttt ctaattgccc gataaacatt tcctttattt gatctcttaa taattttttc
      421 cattttgtat ttatttattg cagagtcttt acttgaaatt tcacatgtgg tttgaaaata
      481 attccttttt tcttcttctg aaaataaatc cattttccag ttagggagac tagggaaatt
      541 ttgtctctta tcttctacat agttcttcct tttttcatct agcaataaat agatgacttt
      601 tttatttttt tcatcataag cttgtttttt taaaaaagcc ccatatctat aatgaactgg
      661 agaatgcatt ccacattgat agtcagatag tatttttgga gccttaaatt ctgacagtct
      721 attcgtaaga ttacaaatca tactcttagc ttcagattct gacttaggat atagagttat
      781 aaatttgtta gcagtagggc tcatttccct agggaattaa ttttttttaa ttcctctaaa
      841 tttttaacga ctttaaagct acaattattt agttgggata gtttatacac aatcttaaaa
      901 atatttacag cgtcttttat ttgggagctt atgtgtattt tccacccttg tgcaggcacc
      961 ttatctgata aataatagta attccaaata tcaccctgtt ggaaattttt atcacatttt
     1021 aaacattctt tctctaataa atccataaca aactcctaat tattaaaata ggctagagac
     1081 acagcactag cctattccgt aagtaaagct acttatttta tataaaatat aactagcgac
     1141 ctgtaattaa acaagtaaaa gaacaatact tagggagacc tgtgacaatg acatcttcct
     1201 ctggaagtag ttctaattca aacaatgttt gttccatgac tgtatcttcc tgttatgata
     1261 aattccagaa agcatagagc aaattcgtgg ttcgtctgac taaatttctt atctgaacac
     1321 caccttcaaa tacaaatttt agtcaaactt ttattttttc taactttcta attatattct
     1381 accatgtgtt ttttatatgt caagaatttt ctgaataaac tgtttatttt ttattttttg
     1441 atatttttgc aaattgttta aaatctttca attggattca cttattactt taggacattg
     1501 aaacttcttt cgccagaggt gcttatatta ctgggaagtt gaagattgaa atgtggtata
     1561 ataagaggta atagagtttt ggaaagtgag agaagatgat ttcaaagaga ttagaattgg
     1621 tagcttcctt tgtgtcacag ggggctattt tactagatgt gggaagtgac catgcttatc
     1681 tgcctatcga gttggttgag agaggccaag tcaaaagcgc tattgcaggt gaggtggtgg
     1741 aaggtcccta tcagtctgcg gttaaaaatg ttgaggctca cggcctaaag gagaaaatcc
     1801 aagtccgttt agccaatggc ttggcagctt ttgaagagac tgaccaagtg tctgtcatta
     1861 ccattgctgg catgggtggt cgtttgattg ctaggatttt agaagaaggt ttgggtaagt
     1921 tagctaatgt agagcgtttg atcctccagc ccaataatcg tgaagacgac ttgcgtatct
     1981 ggctacagga tcatggattc cagattgtag cagaaagcat cttagaagaa gctggaaagt
     2041 tttatgagat tctagtagtg gaaactggag aaatggaatt atcagcaaga gatacccggt
     2101 ttggcccctt cttgtcaagg gaaatcagcc cagtatttgt ccaaaaatgg caaaaagaag
     2161 ctgagaagct agagtttgcc ctcggacaaa tcccagaaaa aaatctggaa gaacgtcaag
     2221 ttctagtaga taagattcaa gctatcaagg aggtgctcca tgttagcaag tgaagtgatc
     2281 caagcttatg aagccttttg ccctcaggaa ttttctatgg agggagacag ccgtggtctg
     2341 caaattggca ctttagacaa gggtatccaa agggtcatgg ttgccctcga tattcgtgaa
     2401 gagacagtgg cagaggccat tgaaaagggt gtggacttga ttatcgtcaa gcacgcgcct
     2461 atctttcgtc ctatcaagga cttgcttgcc agccgtccgc aaaatcagat ttacatcgac
     2521 ctgattaagc atgacatcgc agtttatgtc agccatacca atattgatat cgttgaaaat
     2581 gggctcaatg actggttttg tcagatgcta ggaatcgagg agacgactta tctgcaggaa
     2641 acaggtccag aacgtggaat tggacgtatt gggaatattc agcctcagac attttgggaa
     2701 ttggcccaac aggtcaagca agtctttgac ctagatagcc ttcgaatggt gcattatcaa
     2761 gagaatgatt tgcagaagcc tatttcaaga gtagcaattt gtggtggaag cgggcagtct
     2821 ttctataagg atgctttggc aaagggggca gatgtctata tcactggtga tatctactac
     2881 catactgctc aggatatgct gtctgatggc ttgttagcat tggatccagg tcactatatc
     2941 gaagtgcttt ttgtggaaaa aatcgcagca ctccttactc aatggaaaga gaaaaaaggc
     3001 tgggaactag agattttacc tagtcaagca tcgaccaatc ctttccgtca tatctagtta
     3061 gaaagtgaag acaatgaaaa aagttgccat tattggagca ggaattgtgg gagcaacagc
     3121 tgcctactac ctctcgagag aaagtgacct agaggtgacc gtttttgacc atgagcaagg
     3181 tcaagccacc aaggctgcag caggaattat cagtccttgg ttttccaaac gccgtaataa
     3241 agcctggtac aagatggcgc gcttgggggc tgatttttat gtggatttat tagctgattt
     3301 agagaaatca ggacaaaaaa tcgactttta ccagcgttcg ggagtctttc tcttgaaaaa
     3361 ggatgaatct aagttggaag aactttatca actggccctc cagcgcagag aagaatctcc
     3421 cttgataggg caattagcca ttctggacca agcctcagct aatgaattat tccctggttt
     3481 gcagggattt gaccgcctgc tctatgcttc tggtggagcg agagtagatg gccacctctt
     3541 agtgactcgt ttgctggaag ccagtcaggt caagctggtc aaagaaaaag tgactctgac
     3601 accgttagca tcaggctacc agattggtga agaggagttt gagcaggtta ttttggcgac
     3661 gggagcttgg ttgggggaca tgttagaacc cttgggttat gaagtagatg ttcgtcctca
     3721 aaaaggacaa ctacgagatt atcagctggt ccaagacatg gaagcttacc ctgttgtcat
     3781 gccagaaggg gagtgggatt tgattccttt tgcaggtggg aaattgtcct taggcgctac
     3841 ccacgaaaat gacatgggat ttgatttgac ggtagatgaa accttgctcc aacaaatgga
     3901 ggaggccacc ttgactcact atctgatttt ggctgaagct acttcaaaat ctgagcgtgt
     3961 tggaatccgt gcctacacca gtgatttctc tcctttcttt gggcaggtgc ctgacttaac
     4021 tggtgtctat gcagccagtg gactaggttc atcaggcctc acaactggtc ctattattgg
     4081 ttaccattta gctcaactga tccaagacaa ggagttgacc ttggaccctg aaaactaccc
     4141 aattgaaaac tatgtcaaac gagtaaaaag cgaataatac tcaatgaaaa tcaaagaaca
     4201 aactaggaaa ctagccgcgg gttactcaaa gcgctgcttt gaggttgtgg atagaactga
     4261 cgaagtcagt aaccataccc atggcaaggc gacgttgacg tggtttgaat tggattttcg
     4321 aagagtataa gcattttact gaaattttat caggtagttt aggatggcaa atgacattcc
     4381 ctgtcaaaaa tggtaaaata agaaaaaata atctgagaat cgaggaaaaa agatgcaaga
     4441 aaagattttg gtaactggtg gtgccggttt tattggaacc cacactgtta ttgaattgat
     4501 ccaagcaggc catcaagttg ttgtggtgga taatcttgtc aatagcaatc gtaagagttt
     4561 agaagttgtt gaaagaatca caggagttga gattcctttc tatgaggcag atattcgtga
     4621 cacagatacc ctcagagata ttttcaagca ggaagaactg actggtgtca ttcactttgc
     4681 tggtttgaag gctgttggcg aatcaacacg tatccctctt gcctactatg acaacaatat
     4741 cgctggaact gtcagccttt tgaaagccat ggaagaaaac aactgtaaaa acatcatctt
     4801 cagttcttct gcgacagttt acggggatcc gtacacagtg cccatcttgg aagatttccc
     4861 actttcagtg accaacccat acggtcgtac caagctcatg ctagaggaaa ttttgaccga
     4921 tatttacaaa gcagactcag aatggaatgt tgtcttgctt cgttacttta acccaatcgg
     4981 agcccatgag agtggtgatt tgggagaaaa tccaaacggt attccaaaca atctcttgcc
     5041 atatgtgact caagtagccg ttggaaaatt agagcaagtg caagtgtttg gagacgatta
     5101 cgatacggaa gatggaacag gtgttcgtga ctatatccac gttgtcgatt tggctaaggg
     5161 tcacgttgca gctttgaaaa aaatccaaaa aggttcagga ctaaacgttt ataaccttgg
     5221 aactggtaaa ggttactcag ttcttgaaat tatccaaaac atggaaaaag cggtgggacg
     5281 tcctattcct taccgcatcg tagaacgtcg cccaggtgat atcgctgcct gctactcaga
     5341 cccggcaaaa gctaaagcag aactcggttg ggaagcagaa ctcgacatca cccaaatgtg
     5401 tgaagacgca tggcgttggc aaagcaagca tccaaatgga tttgaagact aagatgatga
     5461 tttcaatcat cgtcccttgt ttaaatgaag aggaagtact tcctcttttt tatcaggctc
     5521 tggaagcttt acttccagat ttggaaacag aaatcgagta tgtctttgtc gatgatggat
     5581 caagtgatgg gaccttggaa ctcttaaagg cctatcggga gcaaaatccg gcagtccatt
     5641 atatttcttt ctctcgaaat tttggcaaag aagcagccct ttatgcaggc ttgcaatatg
     5701 cgacaggaga tttggtggtg gtgatggatg cagacctcca agatcctcct agtatgttgt
     5761 ttgagatgaa aaatgtacta gacaaaaatg tagacttgga ctgcgttggg acacggagaa
     5821 ctagtcggga gggagaaccc ttctttcgca gtttctgtgc tgttctcttt tatcgcctca
     5881 tgcaaaaaat cagcccagta gctctgccgt cgggtgtccg tgactttcgt atgatgagaa
     5941 ggtctgtggt cgatgccatt ttaagcttga ctgagtccaa tcgtttttct aagggactct
     6001 ttgcctgggt cggctttaaa acccactatc tggactatcc aaatgtcgaa aggcaggctg
     6061 gcaagaccag ttggagtttt aggcaactct ttttttactc cattgaaggg attgttaatt
     6121 tttcagattt ccctttgact atagcctttg tagctggtct cctatcttgt tttctttctc
     6181 tgctgatgac cttttttgtt gtggttcgga ccctcatttt gggcaatccg acatctggtt
     6241 ggacctctct gatggctgtt attctctttc ttggaggcat tcaactcttg accattggga
     6301 ttctcggcaa gtatatcagt aagatttatt tagagactaa aaaaagacca ctttatctta
     6361 tcaaagaaaa aagtgacctt cctgatttta cagaaaaaat aaagtgaaaa gactataatt
     6421 ttacatggaa atgtgctaaa ctagagggag tggattatcg ccattgattt aggcttcctg
     6481 gtttccaatc agggcgcgag ttgggcaatt tttaacagcc tctaagacat cctgactagg
     6541 agaaatttct ttttccagtt ggtcagggtc atcgtaaaaa cgcacgattc cattatcatg
     6601 gtaatcaaat aaatcagaat aagtttggca aagcccacag gcgatacatc gttcaggtat
     6661 aagtgtgatt ttcatgttca tatttatatt gtaataagaa aagtaaaaaa aaacaaggag
     6721 taaggtatgg caaaagaacc gtggcaagaa gatatctatg atcaagaaga atcaagagca
     6781 gagcgtcggc ctcgaaacca cggaggggct gataggatgg ctaatcgtat tttgacgatc
     6841 ctagctagta ttttctttgt aattgtggtg gtgatggtca tcgttctcat ctatctatca
     6901 tcggggggga gtaatcgcac agcagcctta aaagactttc atgattctga tgcaagtgta
     6961 gtacaaatct catcttcaag cagttctcag cctgagcaga gttcagagcc agaatctact
     7021 tctagtagtt cagaaggagc tgctaatcct gaaggaacta ttaaagttct cgcaggagaa
     7081 ggggaagcag ctattgccgc tcgtgcagga atctccattg ctcagttaga ggccttgaat
     7141 cctgggcaca tggctacagg atcttggttt gctaatccag gtgatgttat aaaaataaaa
     7201 taggagccga tatgaaaaca attcaaattg ctattgatgg tcctgcttcc agcggtaaga
     7261 gtacggtcgc aaagattatt gctaaggatt ttggattcac ctaccttgat acaggagcta
     7321 tgtatcgtgc agcgacctat atggctctta agaaccaatt aggagttgaa gaagtcgaag
     7381 cccttctagc cttgttggac cagcattcaa tcagctttgg acgttcagaa actggagacc
     7441 agcttgtttt tgtaggagat gtggatatta cccatcctat ccgtgaaaat gaagtgacca
     7501 atcatgtttc tgctattgca gcaattcctg aagtgcgtaa gaaattggtt tctctccaac
     7561 aagaaattgc ccagcaaggc gggattgtca tggatggtcg cgatattgga actgttgtat
     7621 tgccacaagc agaattgaaa attttcctag tagcttctgt tgatgagaga gcagagcgtc
     7681 gttacaagga aaatattgcc aagggaattg aaacagacct tgaaacccta aaaaaggaaa
     7741 ttgctgcgcg tgactacaag gatagtcatc gtgagacttc tcctctcaaa caagcagagg
     7801 atgctgtcta ccttgataca actggtttga acattcaaga agtagttgaa aaaatcaaag
     7861 cagaagctga aaaaagaatg taaatgtaga aaagccgata gattgatatc ggtttttttc
     7921 taaatttgtc aaaatgctga ttttagggta taatagttgc tgttcgagaa attttgattt
     7981 tcaaagaata gtgaatgatg ataaggagaa atcatgaaca atttaccaaa ttgtccaaaa
     8041 tgtaactcag agtatgtcta cgaagacggt gccctactgg tttgcccaga gtgtgctcat
     8101 gagtggaatc ctgctgaagt tgcagaagta gaagaaggtc ttgtcgctat cgatgccaac
     8161 ggaaataaat tggctgatgg tgatacagta actctcatca aggacttgaa agtaaaaggt
     8221 gcgccaaaag atttgaaaca agggacgcgc gtgaaaaata tccgcatcgt agaaggcgac
     8281 cacaatatcg actgtaagat tgatggtttt ggtgccatga aactcaaatc agagtttgtg
     8341 aggaagattt aagcatgtca aaacactata aacttgtatt ttatagccgt atcttcttgt
     8401 ttctagcggc ttttacggga gtttatcttg aaattactaa gcatggtggt tttgggatgc
     8461 ttctctatta cacggttctg tccaacctct tggtaactat ttttaccctt tatcttctaa
     8521 aggttatgag ccgtgtaggt gaaaattggc aaaggccaag tctcttgcgc ttaaaaggtg
     8581 gggtcaccat gagtatcatg attacctgtg tgatttacca tttcctcttg gcgcccattg
     8641 cgactaattt ctatacccta gaaaatttcc tttgccacta tatcgttccc atctggtttt
     8701 tagcggatac cctctttttt gacaaacagg gtcaatacaa gatttgggat ccagcagtgt
     8761 ggaccatttt accctttctg tatatgatgt ttgctctttt taatggcttg gttctaaaac
     8821 tcaatattcc aaatgccaag gataatcctt tcccttactt ctttttgaat gtgaacaagg
     8881 gttggaatgt tgtgtttaag tggtgtctga ttatctttgt tgcctatatg gtagcaggat
     8941 ttattttcta ctttatcaag caaatcaaga gaaagtcatc ctaatactct tcgaaaatct
     9001 cttcaaacca cgtcagtttc catctgcaac ctcaaaacac tgttttgaac aacctgcggc
     9061 tagcttccta gtttgctctt tgattttcat tgagtataag atacaaggga ttcattttcg
     9121 aatttaagaa ggagtctaca aaccaatgag gcttcttctt ttcttgctta tttgataact
     9181 atcaaaaaag tagaagatta agagaaatat agaaagagat ttcatgaaac aatttttaga
     9241 acgggccagc attttggctc tctccctcgt tttgattacc tccttttcca tttcgagtgc
     9301 cctaccagcc atgtttgact attatcaggg ttattctaag gaacaaattg agctcttggt
     9361 gagcttgcct tcctttggaa tcatgatgat gttactgcta aatggtttct tagaaaaaat
     9421 atttcctgag cgcttacaga ttagtttggg cttgctgatt ttatcattga gcggtacagc
     9481 tcccttctgg taccaagcct atccctttgt ctttggaaca cggcttctct ttggtttggg
     9541 tcttgggatg atcaatgcca aggccatttc tattatcagt gaacgctacc aaggaaaaag
     9601 gcgaattcag atgttagggc tacgcgcttc tgcagaggtc gttggagctt ctctcattac
     9661 cttggccgtc ggtcagttgt tggcctttgg ttggacagct atctttctag cctatagtgc
     9721 tggatttttg gtgctgcccc tttatctgct ctttgtccct tatggaaaat caaagaaaga
     9781 agtcaagaaa agagcgaagg aagcaagtcg tttaactcga gaaatgaaag gcttgatttt
     9841 taccttagct atcgaagcgg cagttgtagt ttgtaccaat acagctatta ccatccgtat
     9901 tccaagtttg atggtggaaa gaggattggg ggatgcccag ttatctagtt ttgttcttag
     9961 tatcatgcag ttgatcggga ttgtggctgg ggtgagtttt tctttcttga tttctatctt
    10021 taaagagaaa ctgctcctct ggtctggtat tacctttggc ttggggcaaa tcgtgattgc
    10081 cttgtcttca tccttgtggg tggtagtagc aggaagtgtt ctggctggat ttgcctatag
    10141 tgtagtcttg acgacggtct ttcaacttgt ctctgaacga attccagcta aactcctcaa
    10201 tcaagcaact tcatttgctg tattaggctg tagtttcgga gcctttacga ccccattcgt
    10261 tctaggtgca attggcttac taactcacaa tgggatgttg gtctttagta tcttaggagg
    10321 ttggttgatt gtaatctcta tctttgtcat gtacctactt cagaagagag cttaggattg
    10381 attcctaagt ttttcttttg atactcaatg aaaatcaaag agcaaactat agttgattga
    10441 gtttggaata gtatgctgta gctgctaaaa tatttctaga aattaatttg actttcctaa
    10501 tagagttgtt catatcttat ttcaatctac tatagaaagc tagccgcagg ttgctcaaaa
    10561 tagtgtgttg aggttgcaga tggaaactga cgtggtttga agagattttc gaagagtatg
    10621 agatttttat acccatacag tatttgtttt aggtccttgt ttacagacta atttcttgat
    10681 aaaatagagg ctatgacgag atataaagca actatttcct atgatggtta tgcctttgct
    10741 ggctttcagc gccagcctca tgcgcgtagc gttcaggaag aaattgaaaa aaccttgacc
    10801 agattaaata aagggcaagt cattactgtt cacggtgctg gtaggacaga tagtggggtt
    10861 catgccctgg gacaggtcat tcattttgac ctgccttatc agatggatga ggagaaactc
    10921 cgttttgcct tggataccca gtctcctgaa gatattgatg tgatttcgat tgagcttgtg
    10981 gcagatgatt ttcattgccg ttatgccaag catagcaaga cctatgagtt tactgtggat
    11041 agaggacgtc ccaaaaatcc gatgcgccgt cactatgcta cccactttcc ctacccactc
    11101 gatgtggaac gaatgcagat tgcaatcaaa aagctagagg gaacccatga ttttaccggt
    11161 tttacagcct ctgggactag tgtagaggat aaggttcgca ccatcacaga agctagttta
    11221 atagtcgatg agacaggaca atttttgacc tttacctttt caggaaatgg tttcttgtat
    11281 aaacagattc gcaatatggt ggggactctt ctcaaaatcg gtaacaaccg catgccagta
    11341 gagcagattg atctcatctt ggagaagaag gacaggcaac ttgcaggtcc cactgcagca
    11401 ccaaatggtt tgtatttaaa ggagattcgt tatgaagaat aatcgtattt tagcactttc
    11461 tggaaatgat atttttagtg gtggtggact gtcggctgat ttggctacct ataccttgaa
    11521 cgacttgcat gggtttgtag cagtgacttg tttgacagcc ttgacagaaa aaggatttga
    11581 agtctttcca actgatgata ccatttttca acatgaatta gatagcttgc gtgatgtgga
    11641 atttggggga attaagattg gtcttctccc tactgtcagt gtggctgaga aggccttgga
    11701 ctttatcaaa caacgcccag gagtatctgt ggtgctggat cctgtcttgg tctgcaagga
    11761 aacgcatgat gtagctgtca gtgagctctg ccaagagttg attcgctttt tcccttatgt
    11821 cagtgtgatt acgcctaatc tcccagaagc agaattatta tccggtcagg aaattaaaac
    11881 cttggaagac atgaaaactg cagcgcagaa attgcatgat ttaggagcgc cagcagtcat
    11941 tatcaaggga ggcaatcgtc ttagtcagga caaggctgtg gatgtctttt atgatggaca
    12001 gacctttact atcctagaaa atccagttat ccaaggccaa aatgctggtg caggttgtac
    12061 ctttgcctct agcattgcca gtcacttggt taaaggtgat aaacttttgc cagcagtaga
    12121 aagctctaag gctttcgttt atcgtgctat tgcacaagca gatcagtatg gagtaagaca
    12181 atatgaagca aacaaaaaca actaaaatcg cccttgtatc cctattaacc gccctttctg
    12241 tggttctagg ttatttctta aaaatcccaa cacctacagg aattctaact cttttagatg
    12301 ctggtgtctt ctttgcggcc ttttactttg gtagtcgtga aggagcggta gtcggaggac
    12361 tagcaagttt cttgcttgac ctcttatcag gctaccctca gtggatgttt tttagcttgg
    12421 tcaaccatgg cttgcaggga tttttcgcag gatttaaagg aaaaagtcag tggttaggcc
    12481 ttattttagc aactattgcc atggtagggg gctacgcctt gggttctact ttgatgaatg
    12541 gctgggcagc agccctccca gaaattctac caaattttat gcaaaatatg atagggatga
    12601 ttgtaggatt tattcttagt caaagtatca agaagattaa gtaatactct tcgaaaatct
    12661 cttcaaacca cgtcagcttc catctgcaac ctcaaaacac tgttttgagc agcctgcggc
    12721 tagctttcta gtttgcactt tgattttcat tgagtataaa aagatcttgg gaaaagactc
    12781 aatttcagta gaaaaggaag taaatcttcc cacattaaaa cgcatattac caaggttctt
    12841 atgaactgca ccccaaaagt tagacaaaaa aaatctaact tttgggtgtt tttattatga
    12901 aattga
//
LOCUS       DAVKBC010000046        12637 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVKBC010000046 DAVKBC010000000
VERSION     DAVKBC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12637
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.046"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(150..587)
                     /locus_tag="VWX64_001692"
     CDS             complement(150..587)
                     /locus_tag="VWX64_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU9191121.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(672..3305)
                     /gene="polA"
                     /locus_tag="VWX64_001693"
     CDS             complement(672..3305)
                     /gene="polA"
                     /locus_tag="VWX64_001693"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU9191122.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGVKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHIELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3561..3911
                     /locus_tag="VWX64_001694"
     CDS             3561..3911
                     /locus_tag="VWX64_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU9191123.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4126..4242
                     /locus_tag="VWX64_001695"
     CDS             4126..4242
                     /locus_tag="VWX64_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU9191124.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4235..4486
                     /locus_tag="VWX64_001696"
     CDS             4235..4486
                     /locus_tag="VWX64_001696"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191125.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGLSVSEFEPFCVEKSPI"
     gene            4530..4808
                     /locus_tag="VWX64_001697"
                     /pseudo
     CDS             4530..4808
                     /locus_tag="VWX64_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4945..5913)
                     /locus_tag="VWX64_001698"
     CDS             complement(4945..5913)
                     /locus_tag="VWX64_001698"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9191126.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(6058..6600)
                     /locus_tag="VWX64_001699"
     CDS             complement(6058..6600)
                     /locus_tag="VWX64_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU9191127.1"
                     /translation="MDQLLGVLFPDSTFLNAFESAIVAPLVEEPLKLLPLVFVLALIP
                     VRKLKSLFLLGIASGLGFQMIEDIGYIRTDLPEGFDFTISRILERIISGIASHWTFSG
                     LAVVGVYLLYRAYKGQKVGKKQGLIFLGLALGTHFLFNSPFVELETELPLAIPVVTAI
                     ALYGFYHAYCFVEKHNELMT"
     gene            complement(6604..6888)
                     /locus_tag="VWX64_001700"
     CDS             complement(6604..6888)
                     /locus_tag="VWX64_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191128.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFLALFYM
                     IPALYFLFHIGKKWELPKKVLILSLLGAICSFTSLLLFGIYNHRRKSSKV"
     gene            complement(6913..7410)
                     /locus_tag="VWX64_001701"
     CDS             complement(6913..7410)
                     /locus_tag="VWX64_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU9191129.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(7483..8844)
                     /gene="radA"
                     /locus_tag="VWX64_001702"
     CDS             complement(7483..8844)
                     /gene="radA"
                     /locus_tag="VWX64_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU9191130.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(8858..9373)
                     /locus_tag="VWX64_001703"
     CDS             complement(8858..9373)
                     /locus_tag="VWX64_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9191131.1"
                     /translation="MKIIFVRHGEPDYRELEERFYIGFGIDLAPLSEMGRQQVQKLSK
                     TPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(9375..9818)
                     /locus_tag="VWX64_001704"
     CDS             complement(9375..9818)
                     /locus_tag="VWX64_001704"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU9191132.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(9878..9971)
                     /gene="ffs"
                     /locus_tag="VWX64_001705"
     ncRNA           complement(9878..9971)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VWX64_001705"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(10004..10471)
                     /locus_tag="VWX64_001706"
     CDS             complement(10004..10471)
                     /locus_tag="VWX64_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU9191133.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(10672..11958)
                     /locus_tag="VWX64_001707"
     CDS             complement(10672..11958)
                     /locus_tag="VWX64_001707"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU9191134.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(12189..12425)
                     /locus_tag="VWX64_001708"
     CDS             complement(12189..12425)
                     /locus_tag="VWX64_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU9191135.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT         3968 a         3067 c         2133 g         3469 t
ORIGIN      
        1 caacctcaaa acggtgtttt gagctgactt cgtcagttct atctacaacc tcaaaacagt
       61 gttttgagca acccgcagct agtttcctag tttgctcttt gattttcatt gagtataaca
      121 caaaaggtag cccatcagct acctttttct tatgcttcct caatcaagcg agtatgttct
      181 ctcttgatac agcgattcat cacgatatca tcacatccac catcacgcaa aatctctttc
      241 gcttctaaac tttcaagtcc tagctgtgcc caaaaaatct tggcatcagc tttgagaaaa
      301 tcacgcgcca catcgggcag aaattcactg cgacgataaa cattgacaat atctacagga
      361 aaaggaattt cagcgaggct agcataagcc ttttcaccca agatttcgcc acctgccgcc
      421 ttgggattga ctgggatgat tttatagccc cgagcctgca tttcctttgt tactcgattg
      481 ctggttgttt cttcacggtc agacaaaccc accacagcaa gggttttact cgttgcgaga
      541 tactgacgaa tcacgccatc acttggattg ataaattctt gactcataga aatcctcctt
      601 tttcatcagt atagcacatt ttgaaaaggt ttgcagaatt ctactacaaa aaaggaggac
      661 tagccccctt tttatttagc ctcgtaccag gttgcccctt cattctcatc tgcgataaga
      721 ggaacactga gttgaatggc ttcttccatg gtttgtttca ccaatttttt catctctacc
      781 aattcagatt taggcacttc aaggacgatt tcatcgtgca cttgtaacag catcttagtc
      841 tgataaccac ctgcaaccaa ggctttatcc agctgaatca tggcaatctt gagaatatct
      901 gctgccgaac cctggatagg tgagttgata gcagttcgct ccgcaaaacc acgaatattg
      961 aagttgcgcg aattgatatc tggcaactca cggcgacgct taaagagggt ctctacatag
     1021 cccttatcac gcgcctcccg caccacttca tccatgtagt ttttaatacc tggaaaacgt
     1081 tcaaagtagg tatcaatgta ggctttagct tccttacgac taattcccaa attattagac
     1141 aagccaaagt ctgaaatccc ataaaccact ccaaagttaa ctgccttggc attgcgacgg
     1201 tcgtttgcag tcacatcatc aggacgctca atgccaaaga cccgcatggc tgtcgaagta
     1261 tggatatctg ccccctcttg gaaggcctta atcaagtgct catccttaga aatatgcgcc
     1321 aaaacgcgca attcaatctg tgaatagtca gagctgagta gcacactatc ctcccactct
     1381 ggcacaaaag ccttccgaat caagcgcccc tgttccaatc gggcaggaat attttgcaag
     1441 tttggatcca cactagacaa acgcccggtt tgggtcaaat cctgcacata gcgagtatga
     1501 atctttccat cagccaaaat ccagtcctgc aagccaatta cataagtaga ttgaatctta
     1561 gcaatttgac ggtaatccag gattttctta acaatcggag caataggagc gagacgctcc
     1621 aaaacatcca ctgctgtcga ataacctgtc ttggttttct tagtgtattc tagaggaagt
     1681 cccaatttct caaagagaag cacgcccaac tgcttaggcg agttgacatt aaactcctca
     1741 ccagccagct cgtaaatctc ttgagtcagt ttttcaatga caagctcatt ttcagcctgc
     1801 atctcaagca aggtctcttt cttgaccata atcccagcaa tttccatctt ggcaaggaca
     1861 aaagccagag gttgctccat atcataaaga agctctaatt gcccattttc gctgagtttt
     1921 tcaagtaaaa taggctctgt ttctaccaaa acagcaagtt tacaagctaa gtgttccaag
     1981 aatttctcac gttcaggaat ggccttttta acacccttac cgtagaaagt ttcatcatca
     2041 accaagtaag tctgaccata aagactagcg atggtcgcaa tttcattgtc ctccacagtc
     2101 gaaaggaggt atttagccaa acggatgtca aaagcaggcg cctgcaaatc cacaccaaaa
     2161 cgttgcaaaa gaactttaac cttcttaaag tcataaactc tcagagatgt tttttctaag
     2221 aaatccttga aaatcgggtc ttgcaacagc tcaagcttgt ctgtggcata gagcttatcc
     2281 ccacaagacc aggcaaatcc aaccaaatta tccgtatggt aattctcacc aaaaagctca
     2341 atgtggaaga tagactcttc actcagcata tcttgactga tttggtcaac aatagtaaaa
     2401 tccaaaccct cagccacatc agctgacgac acatttaaag cctgcttgag ctgtttgaag
     2461 cccatctcat cgtaaaattt cccaagattt tcaacatctg gaccactata gaccaagtcc
     2521 tctaaaccaa tcgcaatcgg tgccttggta tcaatggtcg ctagtgtttt agacaaaaag
     2581 gcctgttcct tgtcattgat gagattttcc ttcatcttag aagtcttcat tccatcaata
     2641 ttttcataaa tcccctcaag cgaaccatgc tccagcaaga gcttaacacc cgtcttttca
     2701 ccgactttgg tcaccccagg gatattatcc gacttatcac ccatgagcgc cttgagatcg
     2761 ataaactgag ctggtgtgag gcccatttct tccatgaggt aatctggcgt aaaggcctca
     2821 aactcagcca cacctttctt ggaaatttca accaccgtat gctcatccgt cagctgaatc
     2881 aaatccttgt ccccactgac aatggtaata tcaaaaccat cctgctctgc tagcttatcc
     2941 agcgtcccaa tgatgtcatc cgcctcatac tgagccagct catagtgacg aatccccata
     3001 tgatccagca actcacgaat gaaaggaaat tgctcacgaa actcatcagg agtcttggcc
     3061 cgaccaccct tatagtccgc atacatctct gtccggaagg tcgtctttcc cgcatcaaaa
     3121 gccaccaaaa tatgactcgg ctcaacccgc tccaacaaat gactcaacat caactggaaa
     3181 ccataaatcg cattggtatg caaaccagcc gcattcttaa aacggtccaa ctgctgatac
     3241 agcgcaaaaa acgcccgaaa agctacagaa gacccatcaa tcaataataa ttttttctta
     3301 tccatacacc cattataaag gaaagaatca aaaaatacca ttgggaagag ctagagcaag
     3361 tatttttcaa actttttccg aataaataga tagagccaga gaatttagta aacctagatt
     3421 taaaaatgtg ctataacata atatattgaa tctataatag tacaccttga ctgctaaaat
     3481 atttctataa attaatttga ctttcctgat agagttattc acatcttatt tcaactcact
     3541 atagaaggag gaataggagg attctcagac atccgggcat cagcccaact aatgatttga
     3601 ttgctaagaa aatattcagc aatccagaaa tcacttgtca atttattcgc gatatgctgg
     3661 acttgccagc aaaaaatgtg accattttgg agggaagcga tattcacgta ttactctcca
     3721 tgccttactc agtgcaggat ttttatacca gtatagacgt cttggcggag ttggataacg
     3781 gtactcaagt aattattgag attcaagtcc atcatcagaa ttttttcatc aatcacttgt
     3841 ggacttacct gtgcagtcag gttaatcaaa atcttgaaaa aattcgtcag cgagaaggtg
     3901 atactcacta gagctacaaa cacatcgctc ctgtttacgc cattgctatc gtggatagta
     3961 attatttctc agatgacctg gcttttcata gctttagtat gcgcgaagac acaacaggtg
     4021 aggtattggc gattaccaac aatggacagg aaaaccatct ggttaagatg gcattcttgg
     4081 aattaaaaaa tacagagaaa ccagcaagga cgaggttcgc aagccatggt tggagttttt
     4141 cggcaacaag ccctttaccc agcaaccgca acgagccatt acccaagcaa atcaactgct
     4201 ggactacaag agctggtccg aggaggacag gaaaatgttt agtcaactac atatgcgaga
     4261 agaacaagtc ttgttagcac aggactatgc cttggaaact gctagggctg aaggccttga
     4321 acaaggacta gagcgtggga aagttgaagg aagggcagaa aggaaacttt ttgccttcct
     4381 agacatagta cgccaaggtc ttctgacttc tgaggttgcc agccagcaat taggtctgtc
     4441 agtatctgaa tttgagccat tttgtgtaga aaaaagtccc atataaccta taatgaaaag
     4501 cgacaaaaca actcattaga aagaatcata tggaacaatt acattttatc acaaaattac
     4561 tagacattaa agaccctaat gtccagattt taaacatcat caataaggat acacacaagg
     4621 aaatcatcgc caaactggac tacgacgccc catcttgccc tgagtgcgga aaccaattga
     4681 agaaatatga ctttcaaaaa ccttctaaaa ttccttatct tgaaacgact ggtataccta
     4741 ctagaattct ccttagaaag cgtcgattca agtgctatca ctgttcaaaa atgatggtcg
     4801 ctgaaactta tgatgacgta cagtcatatt tcttctcttt ttattatatc acagttttaa
     4861 atctagcttt actagattca ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc
     4921 tgagaatcat ctcaggcttg gtcattaaat ttttttctca atatcgaaaa gtggagaaag
     4981 tggtcgtttt tcatgaatac gtacgatagc atcccctagg agatgagcga ttgaaatctg
     5041 ctcaatctta tcaatcaaac gctcttctgg cagatagatg gtatccaaaa caaccaattt
     5101 cttaatagct gatttttgga tattgtccgt agcaggacca gaaagaactg ggtgcgtaca
     5161 gcttgcatag acttcaacag caccagcttc cgcaagagca tctgccgcat gacaaatcgt
     5221 tccagcggta tcaatcatat catcaatcaa gatacaagtc ttgccttcaa ccttaccgat
     5281 gatgttcata acttcactag tattcatctt atcaacgcta cgacgtttat caataatagc
     5341 gatagatgtt ttcaaaaatt ctgccaactt acgagcacga gtcacccctc catggtccgg
     5401 gctgacaacc acatagtcag aaccaaccat accacgacgc tcaaaataat ctgcaatcag
     5461 aggagcaccc atcaaatgat ccacaggaat atcaaagaat ccttgaattt gcgcagcatg
     5521 caagtcgatg gtcaataaac gatccactcc agctacttca agcatatttg cgacaagttt
     5581 tgaagtgatt ggctcacgcg ctctcgcctt tctatcctga cgtgcatacc catagtaagg
     5641 catgacaaca ttgacagatt ctgcactcgc acgcttcaaa gcatctacca taatcaaaat
     5701 ttcaagcaga ttgtcattta caggcgaact agttgattgt aagataaaga cgtgtttccc
     5761 acggattgat tcttcaatgt tgacctgaat ctctccatct gaaaattggc gaacacttga
     5821 tttccccaac tctatcccaa tctcctgcgc cacacgttct gccaattctt tattagaaga
     5881 aagggcaaac agctttaaat cagaaaaaga catgatttcc tccggtatat atgtataact
     5941 tgtgtttttc acaagatttt ccatctacca ttgtagcgct ttttgcacta tttttcaatc
     6001 aaaaataaaa gaagggcacc atatttgtac ccttgcatca ttcttttgaa aaatattcta
     6061 ggtcatcaac tcattgtgtt tctcaacaaa gcaataagca tgataaaaac catagagagc
     6121 aatagccgta accactggaa tcgctaaagg caactctgtt tccaactcca caaaaggaga
     6181 gttaaacaag aagtgagttc ccaaggctaa acctagaaaa ataaggccct gtttcttgcc
     6241 aaccttctgt cctttatagg ctctgtaaag caagtaaaca cctactacag ctagacctga
     6301 aaaagtccag tgagaggcaa ttcctgagat gatacgctct aaaattcgcg aaatagtaaa
     6361 gtcaaagccc tctggcaaat ccgtacgaat ataaccaata tcctcaatca tttggaatcc
     6421 caaaccggaa gcaattccaa gtaaaaacaa agattttaat tttcgcacag gaatcaaagc
     6481 caaaacaaaa acaagtggca ataatttcaa gggttcttct accaaaggag ccacaatagc
     6541 actttcaaag gcatttaaaa atgtactatc tgggaaaaga acccccagta actggtcgat
     6601 tttttatacc ttagatgact ttcgtctgtg attatagatt ccaaatagta agagagaagt
     6661 aaaggaacag attgctccca ataaagacag aatcaaaacc ttctttggca attcccattt
     6721 tttcccaata tggaagagaa aataaagagc cggaatcatg taaaagagag ctagaaagat
     6781 agaaactccc attagtccat attccgcacc tgacctcgaa ccgtccgtat agtagatggt
     6841 ttcatactgt aaaccaatac atagcaataa aatactgctt ttcttcatac actttctttc
     6901 taaatgaagt atttataatt ctacgactgt catacttcct gtatcaacat tgtaaatagc
     6961 accagagata atgacatcgt ctggtattag gggagactcg ataagcagtt gcatatcctc
     7021 gcgtacactc tcttctatat cttggaaggg caagaagtcc tggtctgaca catctacacc
     7081 taattcctct tttaaatact cctgaaaagg ttcattttca aaggtctgag caccacagtc
     7141 tgtatggtgc aataccacaa tctctcttgt ccccatttgt tgctgggaaa taactagcga
     7201 acgaatcatg tcttcagtca ctcgaccacc tgcattccgc aagatatgag catccccaag
     7261 tgccaagccc agagcttgcg caacgtgcag acgagagtcc atacaggtca caatagctac
     7321 tcttgttttg ggtttaagtg gcagatttaa ctgcccatgt agggcaacat aagcctgatt
     7381 agcttgcata aactgttcaa aatacgacac gattccctcc ttgaaaattt gatagtcaaa
     7441 tatttctcct atcttatcat ttttaagaga atttgtcacg gattatgcaa agaccttttt
     7501 caaaacttcc tgaatcgttg tcacgccaat gacctgaatt tccttaggca gagtgattcc
     7561 tgtcaaggaa ttcttaggta cataaatctt agtaaagccc agtttagcag cttcgttgat
     7621 gcgttgctca atacgattca cgcgccgaat ctctcctgtc aagcccagtt ctccgacaaa
     7681 acattcctga ggattagttg gcttgtcttt gtagctcgaa gcaatagcaa ctgcaacagc
     7741 caagtcaatg gcaggttcat ccaatttaac accaccagca gatttgagat aggcatcctg
     7801 attttgcaag agaagccctg cccgtttttc caaaacagcc ataatcaagc tagcacggtt
     7861 aaaatcaagt cctgtcgtag tacgcttggc atttccaaac atggtcggtg ttaccaaagc
     7921 ctgaacctcc gccaaaatcg gacgcgtccc ttccatggtt acaacgatgg aggaaccagt
     7981 cgccccatcc aaacgctctt ctaggaaaac ttgactcgga ttgagtacct caaccaagcc
     8041 gcccgactgc atctcaaaaa tcccaatctc attagtggaa ccaaaacgat ttttgaccgc
     8101 tctcaaaata cgaaaggtgt ggtgacgctc cccttcaaag taaagcaccg tatccaccat
     8161 atgctccaac atacgaggcc cagccaaggt tccttctttg gtcacatgac ctacgataaa
     8221 gatggcaatg ttattggtct tggccaactg catgagttca gcggtcactt cacgcacctg
     8281 agaaacagac ccctgcaccc ctgaaatctc aggagacatg atggtctgga tggaatcaat
     8341 aatgagaaag tctggctgga tacgctccac ttctgcacga acactctgca tattggtctc
     8401 tgcatagaga taaaactcac tatcaatatc acctaagcgc tctgcacgta gtttaatctg
     8461 ctgggcagac tcctccccac tgacatagag aactgtcccc acttgggaca actgggttga
     8521 gacttgtagg agaagagttg atttcccaat cccaggatcc ccaccgatga ggacgagact
     8581 tcctggtaca actccgcctc caagcacacg gttgaattcc tccatctccg tcttggttcg
     8641 attgacattg atggaagtca cctcagctag tttcatgggc ttggttttct cacctgtcaa
     8701 ggacacacgc gcattcttga cctcggcaac ctcaacctct tccacaaaag aagaccaaga
     8761 cccacagttg gggcaacgtc ccagatattt aggggaatta tacccacaat tttgacatac
     8821 aaatgtcgct tttttctttg cgatgacaaa cctctttcta tatctctaac tcacactcaa
     8881 tcacttggca aaaatcaatc ttctcatttg gcacaaactg gcgcatgagc attcgatgag
     8941 caacaactac cacagtctga tgttctcgat acttagacat acattctaga aaccgagact
     9001 tcatttccgt agctgtctca tattgaatag gactattagg aagcaactcc cccttgtttt
     9061 ctaaaaacag tcttctagct gtttcaaagt tttctattcc tgttttatag acctgccatt
     9121 catgtaataa aggctctact cttaaaggaa gacccgtagc acagaccaca tacgaagccg
     9181 tttctaaagc tcttgtgact gcagaagata cgattatttc agctgacgag agtaaaggag
     9241 ttttgctcaa tttctggact tgctgccgtc ccatctcaga caagggtgcc aaatctatcc
     9301 caaatcctat ataaaaacgc tcctctaact cacggtaatc tggctcccca tgacgtacaa
     9361 agataatctt cattctagtg ccctgtcgat ccaaatccac cagttcgaac gccatcagcc
     9421 gcatctccat ctgcaattaa gaaagtagca aaaacagcct ggacaatacg ctccccaact
     9481 tcaagaacaa cctcttggtc tgtgatattc ttcatctgcg caaaaatatg cccttcattt
     9541 ccaggatttc cataataatc cccatcaatg accccaactg agttaattaa aaccaagccc
     9601 ttcttacgag gatttgaaga acgatcatag aggtagagaa cctcagtcgg ctgcatataa
     9661 gccttaaccc ctgtcggaac caagacaatc tctcctggcg caacaactgt acgcacagca
     9721 acctttaagt cgtaaccagc cgcatgcgct gtctcacgct tgggcaataa attttcatct
     9781 gtaaaactcg aaaccaattc aaaaccacga attttcataa ttttctcttt tctattatca
     9841 tttattctag attattctat cttatttatt cggaaaaagc acgaaaaaag agcacacaat
     9901 tcaaatcgct tagggctgct ggattcctcc cctgacccgc ttcacgcaga actgttgctc
     9961 cactatttat tatatcacat tcctattcat tttaaaagca aaattatttt ttccgtctat
    10021 ttctaaaaaa atcctgcatg atagctgcgc attcatcttc caaaattcct atttcaacct
    10081 ccacacgatg attgagacgc tcatctgtca agatatcgta caaactccca gcagcgccaa
    10141 atttctggtt tttagcccca tagaccacat ttggaatgcg ggcaagccca atcgccccac
    10201 tacacatgac acaaggttca atggtcacaa aaagtgtgca atccagcaag cgccagctct
    10261 cctcactcaa gttcgcatcc tctatagcca taatttccgc atgcataacc gctcgctgta
    10321 attcctcacg cgcattatgc ccacgaccaa tgatttcccc atctttgaca atcacacaac
    10381 caattggaat ttcatcgtgt tcaagagcaa tctcagcctc tctcaaagcc tccctcataa
    10441 agacttcttt ttcttcaagc gtataataca tctcttttct cttttcctac ttatcgattt
    10501 tattattata tcatgaatcc caacacaaaa aaagccaccg aatgcggtga ctctataggg
    10561 agattattat gaaaaagaaa agtttaggat atttgttaca acaagttagg aggtcttctt
    10621 gtaactgtct atagtatacc cgacctatct taaacaaatc ttaaaaatct cttaggacca
    10681 aacactttct aaaatatttg tttgttcacg accaggacct actgagaaag tagaaatacg
    10741 aacgccaacc aattcactca cacgacgaac atagttacgc gcattctcag gaagatcttc
    10801 caaattgcga actccggtaa tatcttctga ccaacctggc aactcttcat agataggctt
    10861 gcaacgtttc aattgctcaa gactagctgg atagtagtca atacgttgac cgtcaagatc
    10921 ataggccaca cagattttca cagtatccaa accgctcaaa acatcaatag agttcaaaga
    10981 aaggttagta ataccagaaa cacgacggct atgacgcatc acaactgagt caaaccaacc
    11041 tacacgacgt ggacgaccag ttgttgtacc atactcatga cccacttcac ggatacgttc
    11101 tcccacttca tcaaacaact cagttgggaa aggaccatct cctacacgac tcgtataagc
    11161 tttacataca cctacaacct tgtcaatctt gcttggaccg acaccagaac caattgtcac
    11221 accaccagct acagggtttg atgacgtaac aaatggataa gtaccttggt cgatatctag
    11281 cataacacct tgtgcacctt caaaaagcac acgtttgcca ttatcaagcg catcattcaa
    11341 gataacagat gtatctatca cgtatttctt gatttgttga ccatattcgt aatattcttc
    11401 aaaaatatca tcgaaaacaa tcgctttact gtcatacaat ttttcaaaaa gacgattctt
    11461 ttcagcaagg ttacgttcta aacgctcacg gaaaatatct ttatctaaaa gatctgcaat
    11521 acgaattcca acacgagcag ccttgtccat ataagctgga ccaattccct taattgtcgt
    11581 accaatctta ttgtcgccct tagcttcttc ttgcaagcga tccaactcga tatgataagg
    11641 caaaataaca tgcgcacgat cagaaatacg caagttatca gttgttacac cttcctcatg
    11701 aagatagctc aactctttta caagagattt aggatttaca accataccat tcccaatgac
    11761 agatattttt tcagggaaga aaatcccaga tggaatcaag tgcaacttaa atttcttacc
    11821 gtcaatcaca atcgtgtgac cagcattatc accaccttgg taacgtgcaa tcacttctgc
    11881 attcgctgaa aggaagtctg taatcttccc tttaccttca tcaccccatt gggtacctac
    11941 aacaacaact gaagtcataa tcttgtctga gccctcaggc tcttcctttc tcacatacat
    12001 ggcaggactc tcacctgcaa ttatatctta caatttatta taataaaaaa tcgccttttt
    12061 atcaagaaga aacaatagaa agatttgcta tttccaacta ttaaaaaatg atttagaaaa
    12121 attactagct atttactatc atctttccat aaaagagtaa attagttcgg aaatttacta
    12181 aaattacctc aacaagaaat aaaaccccga ttcattacca atttttcaag atacaaacga
    12241 taagcaacac gataatggta aacgataaaa tccctacgac aaccaatgcc atatctcact
    12301 aaataataaa ttaaaaattt aaaatgaaca tgttcccagt caaaattatc accaaatgta
    12361 ggaccatact cttcttcaat actatcatag aaattagcca tctgctcata aattttttgt
    12421 aacataatca aatactcctt ttctttttta taaacttatt ctaacaaaaa attttacaca
    12481 ttcactatca attcctgaat tgttaaaata ccagcctcaa caagataaaa ataggaaaag
    12541 ttgacaaaat agaaacaaat ttgttaccta aatttcaaac aattaaagtt ctaaaaagac
    12601 cgccttaaaa cttttgggta aatcctatta gaactat
//
LOCUS       DAVKBC010000047        11964 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVKBC010000047 DAVKBC010000000
VERSION     DAVKBC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11964
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.047"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(153..1784)
                     /locus_tag="VWX64_001709"
     CDS             complement(153..1784)
                     /locus_tag="VWX64_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU9191136.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2077..6987
                     /locus_tag="VWX64_001710"
     CDS             2077..6987
                     /locus_tag="VWX64_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU9191137.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPG
                     ATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGHEVSFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVLAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            7077..8273
                     /locus_tag="VWX64_001711"
     CDS             7077..8273
                     /locus_tag="VWX64_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU9191138.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8409..8936
                     /locus_tag="VWX64_001712"
     CDS             8409..8936
                     /locus_tag="VWX64_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9191139.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9013..9369
                     /gene="glnR"
                     /locus_tag="VWX64_001713"
     CDS             9013..9369
                     /gene="glnR"
                     /locus_tag="VWX64_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU9191140.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9406..10752
                     /gene="glnA"
                     /locus_tag="VWX64_001714"
     CDS             9406..10752
                     /gene="glnA"
                     /locus_tag="VWX64_001714"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU9191141.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10842..10961)
                     /locus_tag="VWX64_001715"
     CDS             complement(10842..10961)
                     /locus_tag="VWX64_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU9191142.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11449..11964
                     /locus_tag="VWX64_001716"
                     /pseudo
     CDS             11449..11964
                     /locus_tag="VWX64_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3834 a         2183 c         2564 g         3383 t
ORIGIN      
        1 tcgatttcta acaatgtttt agaaatagag gtgtactatt ctagtttcaa tatactatat
       61 atctgcagaa tactctttca gtttcattca gcctagtctt gcttaggaaa aagtaagaag
      121 ccatccaatt atgatggata gcttcttggt tcttagattt gttctgcaaa aaccttttca
      181 gcaaggttca tagcgtggtc tgatacacga gtgtagtgtg agatgatgtc gataaagttg
      241 accccagctt gtgttgaaca ttcgcctttg ttgaggcgtt tgatgtgggt ttttctgaga
      301 acacgttcta tcttattgat tgcttcatga cgttctacaa gactgcgtgc tttttcaata
      361 tcattgtttt ccacactatc cagagcatct ttgataaagt cactagtttg gcggtaaact
      421 tcctctaatt ctttcaaggc ggcatcagaa aattcaacat ttttccgttg aagatagtca
      481 gtcagattga gtagagcctc cgtgtggtct ccaatccgtt ccaaatcacg ggaggaatca
      541 aggatattgg tgagcacttc actttctttt tggctgagag cttcgcttga aagggcaatg
      601 agataacgtg ttaattgctc atcgatggtg ttaattgctt cttcggtttt atgccctttt
      661 tcagcaactt tttcatccaa gtcaatgatg tacttatagg aaaggtcaaa ggctttagca
      721 gcgtagtttc ctaagtgcaa gagctctttc ttagcatttc ctagagcgat agatggggcc
      781 tgtttgatga aatgttcatc aagatataag ggttcgtatt ttacaacctc gtcctctcca
      841 ggaataatct tggttacaaa gtaagccaga gctccgataa atggaaattg gacaatggtg
      901 ttggtaatat taaaggttcc gtgagcaaag gcgatggtca tttccggtgc tagatttagc
      961 gtagcttcaa accaatgaat caggacagta aaaggaacta gaaaaataac gcagacaact
     1021 gttccgataa cgttgaaggc aacatgagct cctgctaccc gtttagctgc aatattagcc
     1081 cctaaagagg caatgatggc tgtaatggtt gtcccgatat tgtcaccaaa tagaactggc
     1141 aaagctccct gtaggtcaat tagattgccg gcgtagaggt tttgtaaaat cccaatggta
     1201 gccgaagaag cttgaattag caaggtcaag ccagtaccga caaagacacc caaaacagga
     1261 tttttactta gctcaatcat atagtcctta aagacctgta aatccttgag tggagccatt
     1321 gcgccgctca tgagattgag ggcaaaaaag ataccaccga caccaaagag gatgcgtccg
     1381 atattattga ctgtccgatt tttcgtaaaa aagagacaga cggcaccgat aaagagcata
     1441 ggtagggcat agttacctaa tttaaaaccg atgagaaagg atgtgacagt tgtcccaata
     1501 ttagcaccca tgacaatccc gatagcctga cgtaaggtta agagaccggc actgaccagg
     1561 ccgactgtaa taactgttac accagaacta gactgaatta gagcagtcat cccaatacca
     1621 accagaactc caaagaaagg attactagta tatttgtcaa tgtaaaaacg aaggcgatct
     1681 ccagcagctt gttgcaaacc gtctcccatg gtcttgatgc tatataagaa tagccccaga
     1741 ccacctaaaa agtgaaataa aatttcctgc caattaatgg acatttcttt ttcctccgaa
     1801 aaataatcgc ggaatatctc ctattctatt ttaaaggata aaagtaaatc taacaagtgt
     1861 taatgtcaag tttgtaaaag aaaattataa ttgataagtg tattattttt aagagttttt
     1921 aaccttattt tagatttgtg caaacagtta ttgttttttg tctaaaaatg ttttaggata
     1981 aaaatgtgat tatcatggtt ctagagtttg ataaaaaact acagaatata aagcgctttc
     2041 tttaaaacaa caaaatcaat cttttaggag gagaaaatga agaatccatt ttttgaaaga
     2101 cgttgtcgtt acagtattcg taagttatca gtaggagcct gctcgctgat gattggtgct
     2161 gttttatttg ctggtccagc cttggctgaa gaaactgcag ttcctgaaaa tagcggagct
     2221 aatacagagc ttgtttcagg agagagtgag cattcgacca atgaagctga taagcagaat
     2281 gaaggggaac atgctagaga aaacaagcta gaaaaggcag aagcagctag cgcagctaaa
     2341 ccagaggaaa aagcaggtga ggtggttgca gaaacaccat ctgcagaagc aaaacctaag
     2401 tctgacaagg aaacagaagc aaagcccgaa gcaactaacc aaggggatga gtctaagcca
     2461 gcagcagaag ctaataagac tgaaaaagaa gtccagccag atgtccctaa aaatacagaa
     2521 aaaacattaa aaccaaagga aatcaaattt aattcttggg aagaattgtt aaaatgggaa
     2581 ccaggtgctc gtgaagatga tgctattaac cgcggatctg ttgtcctcgc ttcacgtcgg
     2641 acaggtcatt tagtcaatga aaaagctagc aaggaagcaa aagttcaagc cttatcaaac
     2701 accaattcta aagcaaaaga ccatgcttct gttggtggag aagagttcaa ggcctatgct
     2761 tttgactatt ggcaatatct agattcaatg gtcttctggg aaggtctcgt accaactcct
     2821 gacgttattg atgcaggtca ccgtaacggg gttcctgtat acggtacact cttcttcaac
     2881 tggtctaata gtattgcaga tcaagaaaga tttgctgaag ctttgaagca agacgcagat
     2941 ggtagcttcc caattgcccg taaattggta gacatggcca agtattatgg ctatgatggc
     3001 tatttcatca accaagaaac aactggagat ttggttaaac ctcttggaga aaagatgcgc
     3061 cagtttatgc tctatagcaa ggaatatgct gctaaggtaa accatccaat caagtattct
     3121 tggtatgatg ccatgaccta taactatgga cgttaccatc aagatggttt gggagaatac
     3181 aactaccaat tcatgcaacc agaaggagat aaggttccgg cagataactt ctttgctaac
     3241 tttaactggg ataaggctaa aaatgattac actattgcaa ctgccaactg gattggtcgt
     3301 aatccttatg atgtatttgc aggtttggaa ttgcaacagg gtggttccta caagacaaag
     3361 gttaagtgga atgacatttt agacgaaaat gggaaattgc gcctttctct tggtttattt
     3421 gccccagata ccattacaag tttaggaaaa actggtgaag attatcataa aaatgaagat
     3481 atcttcttta caggttatca aggagacccc actggccaaa aaccaggtga caaagattgg
     3541 tatggtattg ctaacctagt tgcggaccgt acgccagcgg taggtaatac ttttactact
     3601 tcttttaata caggtcatgg taaaaaatgg ttcgtagatg gtaaggtttc taaggattct
     3661 gagtggaatt atcgttcagt atcaggtgtt cttccaacat ggcgctggtg gcagacttca
     3721 acaggggaaa aacttcgtgc agaatatgat tttacagatg cctataatgg cggaaattcc
     3781 cttaaattct ctggtgatgt agctggtaag acagatcagg atgtgagact ttattctact
     3841 aagttagaag taactgagaa gaccaaactt cgtgttgccc acaagggagg aaaaggttct
     3901 aaagtttata tggcattctc tacaactcca gactacaaat tcgatgatgc agatgcatgg
     3961 aaagagctaa ccctttctga caactggaca aatgaagaat ttgatctcag ctcactagcg
     4021 ggtaaaacca tctatgcagt caaactattt ttcgagcatg aaggtgctgt aaaagattat
     4081 cagttcaacc tcggacaatt aactatctcg gacaatcacc aagagccaca atcgccgaca
     4141 agcttttctg tagtgaaaca atctcttaaa aatgcccaag aagcggaagc agttgtgcaa
     4201 tttaaaggca acaaggatgc agatttctat gaagtttatg aaaaagatgg agacagctgg
     4261 aaattactaa ctggctcatc ttctacaact atttatctac caaaagttag ccgctcagca
     4321 agtgctcagg gtacaactca agaactgaag gttgtagcag tcggtaaaaa tggagttcgt
     4381 tcagaagctg caaccacaac ctttgattgg ggtatgactg taaaagatac cagcctacca
     4441 aaaccactag ctgaaaatat cgttccaggt gcaacagtta ttgatagtac tttccctaag
     4501 actgaaggtg gagaaggtat tgaaggtatg ttgaacggta ccattactag cttgtcagat
     4561 aaatggtctt cagctcagtt gagtggtagt gtggatattc gtttgaccaa gccacgtacc
     4621 gttgttagat gggtcatgga tcatgcaggg gctggtggtg agtctgttaa cgatggcttg
     4681 atgaacacca aagactttga cctttattat aaagatgcag atggtgagtg gaagctagct
     4741 aaggaagtcc gtggtaacaa agcacacgtg acagatatca ctcttgataa accaatcact
     4801 gctcaagact ggcgcttgaa tgttgtcact tctgacaatg gaactccatg gaaggctatt
     4861 cgtatctata actggaaaat gtatgaaaag cttgatactg agagtgtcaa tattccgatg
     4921 gccaaggctg cagcccgttc tctaggcaat aacaaggtac aagttggctt tgcagatgta
     4981 ccggctggag caactattac cgtttatgat aatccaaatt ctcaaactcc gcttgcaacc
     5041 ttgaagagcg aagttggagg agacctagca agtgcaccat tggatttgac aaatcaatct
     5101 ggtcttcttt attatcgtac ccagttgcca ggcaaggaaa ttagtaatgt cctagcagtt
     5161 tccgttccaa aagatgacag aagaatcaag tcagtcagcc tagaaacagg acctaagaaa
     5221 acaagctacg ccgaagggga ggatttggac cttagaggtg gtgttcttcg agttcagtat
     5281 gaaggaggaa ctgaggacga actcattcgc ctaactcacg caggtgtatc agtatcaggt
     5341 tttgatacgc atcataaggg agaacagaat cttactctcc aatatttggg acaaccggta
     5401 aatgctaatt tgtcagtgac tgtcactggc caagacgaag caagtccgaa aactattttg
     5461 ggaattgaag taagtcagga accgaaaaaa gattacctag ttggtgatag cttagacttg
     5521 tctgaaggac gctttgcagt ggcttatagc aatgacacca tggaagaaca ttcctttact
     5581 gatgagggag ttgaaatttc tggttacgat gctcaaaaga ctggtcgtca aaccttgacg
     5641 cttcattacc aaggccatga agttagcttt gatgttttgg tatctccaaa agcagcattg
     5701 aacgatgagt acctcaaaca aaaattagca gaagttgaag ctgctaagaa caaggtggtc
     5761 tataactttg cttcatcaga agtaaaagaa gccttcttga aagcaattga agcggccgaa
     5821 caagtgttga aagaccatga aactagcacc caagatcaag tcaatgaccg acttaataaa
     5881 ttgacagaag ctcataaagc tctgaatggt caagagaaat ttaaggaaga aaagacagag
     5941 cttgatcgtt taacaggtga ggttcaagaa ctcttggctg ccaaaccaaa ccatccttca
     6001 ggttctgccc tagctccgct tcttgagaaa aacaaggcct tggttgaaaa agtagatttg
     6061 agtccagaag agcttgcaac agcgaaacag agtctaaaag atctggttgc tttattgaaa
     6121 gaagacaagc cagcagtctt ttctgatagt aaaacaggtg ttgaagtaca cttctcaaat
     6181 aaagagaaga ctgtcatcaa gggtttgaaa gtagagcgtg ttcaagcaag tgctgaagag
     6241 aagaaatact ttgctggaga agatgctcat gtctttgaaa tagaaggttt ggatgaaaaa
     6301 ggtcaagatg ttgatctctc ttatgcttct attgtgaaaa tcccaattga aaaagataag
     6361 aaagttaaga aagtattttt cttacctgaa ggcaaagagg cagtagaatt ggcttttgaa
     6421 caaacggata gtcatgttat ctttacagca cctcacttta ctcattatgc ctttgtttat
     6481 gaatctgctg aaaaaccaca acctgctaaa ccagcaccac aaaacacagt ccttccaaaa
     6541 cctacttatc aaccggcttc tgatcaacaa aaggctccta aattggaagt tcaagaggaa
     6601 aaggttgcct ttcatcgtca agagcatgaa aatgctgaga tgctagttgg ggaacaacga
     6661 gtcatcatac agggacgaga tggactgtta agacatgtct ttgaagttga tgaaaacggt
     6721 cagcgtcgtc ttcgttcaac agaagtcatc caagaagcga ttccagaaat tgttgaaatt
     6781 ggaacaaaag taaaaacagt actagcagta gtagctacac aggaaaaacc agctcaaaat
     6841 acagcagtta aatcagaaga agcaagcaaa caattgccaa atacaggaac agctgatgct
     6901 aatgaagccc taatagcagg cttagccagc cttggtcttg ctagtttagc cttgaccttg
     6961 agacggaaaa gagaagataa agattaaata tcgaaaaatc ttgtgaaatc tttccttata
     7021 tttccaaagt gtgatataat agtttcgaat aaaataaata aaggagtttt tgtaacatgg
     7081 caaaacttac tgttaaagac gttgacttga aaggtaaaaa agtcctcgtt cgtgttgact
     7141 tcaacgtacc attgaaagat ggcgtaatca ctaacgataa ccgtatcaca gcagctcttc
     7201 caactattaa gtacatcatc gaacaaggtg gacgtgcaat tcttttctct caccttggac
     7261 gtgtgaaaga agaagctgat aaagctggta aatcacttgc tcctgtagca gctgacttgg
     7321 cagcaaaact tggtcaagat gttgttttcc caggtgtcac tcgtggtgct gaattggaag
     7381 cggcaatcaa cgctcttgaa gatggacaag ttctcttggt tgaaaacact cgttacgaag
     7441 atgttgacgg caagaaagaa tctaaaaacg atcctgaact tggtaaatac tgggcatcac
     7501 ttggagatgg tatcttcgta aacgatgcat tcggtacagc tcaccgtgca cacgcatcta
     7561 atgttggtat ctcagcaaac gttgaaaaag cagttgctgg tttccttctt gaaaatgaaa
     7621 ttgcctacat ccaagaagca gttgaaactc cagaacgtcc attcgtggct atccttggtg
     7681 gttcaaaagt ttcagacaag atcggtgtta tcgaaaactt gcttgaaaaa gctgataaag
     7741 tccttatcgg tggtgggatg acttacacat tctacaaagc acaaggtatc gaaatcggta
     7801 actcacttgt agaagaagac aaattggatg ttgcgaaagc tcttcttgaa aaagcaaatg
     7861 gtaaattgat cttgccagtt gactcaaaag aagctaacgc atttgctggt tacactgaag
     7921 tgcgtgacac tgaaggtgaa gcagtttctg aaggcttcct tggtcttgac atcggtccaa
     7981 aatctatcgc caaatttgac gaagctttga ctggtgccaa aacagttgta tggaacggac
     8041 ctatgggtgt atttgaaaac ccagatttcc aagctggtac aatcggtgtg atggacgcta
     8101 tcgtgaaaca accaggagtt aaatcaatca tcggtggtgg tgactcagct gccgcagcga
     8161 ttaaccttgg ccgtgcagac aagttctcat ggattagtac gggtggtgga gcatcaatgg
     8221 aacttcttga aggtaaggtt cttccaggac ttgcagcctt gacagaaaaa taagatttta
     8281 taaacaaatc aaagaagaga gggatgaaag ttcctctttt cttttgctta aaataaaaac
     8341 gcttcctctc aactattact cataaaaatc accgatttat gataaaatgg aaatagaaag
     8401 ttgagattat gagttatttt aaaaaatata aattcgataa atcccagttc aaacttggta
     8461 tgcgaacctt taaaacaggt attgctgttt ttctagttct cttgattttt ggcttttttg
     8521 gctggaaagg tcttcaaatt ggtgctttga cagccgtttt tagcctgagg gagagttttg
     8581 atgagagtgt tcattttggg acttcgcgta ttctaggaaa tagtatcggt ggactctatg
     8641 ccttggtctt cttcttatta aatacctttt tccacgaagc cttttgggtg accttggtag
     8701 ttgttccaat ctgcaccatg ttaaccatta tgacaaatgt agccatgaat aacaaagcag
     8761 gggttattgg tggtgtagca gctatgttaa tcattaccct atcaattcca agtggtgaga
     8821 caatttcgta cgtgtttgtg cgtgtatcag aaacgtttat gggagttttt gtcgcaatta
     8881 tcgtaaatta cgatattgat cgtattcgtc tctttttaga gaaaaaagaa aaataatgtt
     8941 acattttata acattatcaa ttgacgtttg tcttttttta gactataata gacagaaaga
     9001 aggaaattgt aaatgaagga aaaagaattt cgccgaaata tggctgtttt tcctatcggc
     9061 agtgttatga agttgaccga tctatcggcg cgtcagattc gttattatga agatcaagag
     9121 ttgatcaagc ccgatcgaaa cgaaggaaat cgtcgcatgt attccttgaa tgacatggat
     9181 cgtctgcttg aaatcaaaga ttatatctct gaaggttata atatcgctgc cattaagaaa
     9241 aaatatgctg aacgtgaagc gaaatccaag aaagcggtta gtcagactga agtacgtcgt
     9301 gcacttcaca atgaactcct ccaacagggg cgttttgctt cagtacagtc accttttggt
     9361 cgcggttagg caaccgcaag tagtcataga ttaaggagaa aacttatgcc aatcacagct
     9421 gcagatattc gtcgtgaagt caaggaaaaa aatgttacct ttattcgtct tatgttctca
     9481 gatattttgg gaaccatgaa aaacgtcgaa attcctgcta cagatgaaca gttagataag
     9541 gtcttgtcga acaaggttat gtttgatgga tcttctattg aaggttttgt acgtatcaat
     9601 gagtcggata tgtacttgta cccggacttg gatacatgga cagtcttccc ttggggagat
     9661 gaaaatggaa gtgttgcagg tctgatctgt gatgtctata caacagaagg tgaaccattt
     9721 gcgggtgacc ctcgtggtaa tttgaaacga gctcttcgtc acatggaaga agttggattc
     9781 aaatccttca accttggtcc agagccagaa ttcttcctat ttaagttgga tgaaaatggg
     9841 gacccaacac ttgaagtgaa tgacaagggt ggctactttg atttggcacc tactgacctt
     9901 gcggacaaca cacgtcgtga gattgtgaat gtcttgacca aaatgggatt tgaagtagaa
     9961 gcgagtcacc acgaggttgc ggttggacag catgagattg actttaagta cgatgaagtt
    10021 ctccgtgctt gtgataagat tcaaatcttt aaacttgttg ttaaaaccat tgctcgcaaa
    10081 cacggacttt acgcaacatt tatggcgaag ccaaaatttg gtattgctgg ctcaggtatg
    10141 cactgtaata tgtccttgtt tgatgcagaa ggaaataacg ccttctttga tccaaatgat
    10201 ccaaaaggaa tgcagttgtc agaaacagct taccatttcc taggcggttt gatcaagcat
    10261 gcttacaact atactgccat catgaaccca acagttaact catacaaacg tttggttcca
    10321 ggttatgaag cgcctgttta cattgcttgg gctggtcgta accgttcgcc acttgtgcgc
    10381 gtacctgctt cacgtggtat gggaactcgt cttgagttgc gttcagtgga tccaatggcg
    10441 aacccttaca ttgctatggc tgttcttttg gaagttggtt tgtatggtat tgaaaataaa
    10501 atcgaagcac cagctcctat cgaagaaaat atctacatca tgacagcaga agagcgcaag
    10561 gaagctggta ttacagacct tccatcaact cttcataatg ctttgaaagc tttgacagaa
    10621 gatgaagtgg ttaaagctgc tctcggagat cacatctaca ctagcttcct tgaagccaaa
    10681 cgaatcgaat gggcaagtta tgcaaccttc gtttcacaat gggaaattga taattattta
    10741 gacctttact aatatagaag aaagattgcc tgtgggtaaa cagtcacaca gcagtctaag
    10801 ccatcaaata cctataaccc ttaaaatagc gatttcggtc gctatttatt tttcgaaaaa
    10861 tcctcttgac tcttttgcga attagattta tcatcagacg tgtagaagaa aatcaaggag
    10921 tcactatgga aaaattcaat ttcaaaaaca atatcgggca agaaaacaag ttacttcaaa
    10981 tcgaaatcta caagtttact aacttttgca agcttcaaaa ttacacatct gtaaatattt
    11041 tttcgaaaga tatatttgaa gccatagtaa attgagacta gaatagtaca ctacatctgc
    11101 taaaaatttc tagaaattaa tttaactttc ctaatcgatt tgtttacatc ttatttcaat
    11161 ctactatatt atctcaataa atgatgatgg cgactgtttt gtttgtgctt gtcgattttt
    11221 gaatcctgat cgagcggaag aatatttctg ccgaggttgt caaggggaaa atcctgaaga
    11281 tattgaattt tatgatgaac aattacaggc agaaaaggtg gaggctttga atattcgatt
    11341 ggaagtaaaa aattgaatta tctacaatct catcaacaat aaacctattt caaccccatt
    11401 atctataggc gtatttttac gcctttttat atacttgaag cacataagaa acattatggg
    11461 aagtttgctg atggaagcac tcaagaaatt gatgttcctt atgatattcc tgatacttgg
    11521 gagtgggtga ggataaaatc aatttattgg aattttgggc aaaataagcc agagaaatcc
    11581 tttaggtata tagatacgtc tagtattgat agaaaaaaga acataatcaa ctacaaaaat
    11641 ctacaatatc tttcacctga acaagcgcct tcccgtgcta gaaaattagt ttcgcagaat
    11701 agtgtcttat tttcaacagt tagaccatat ctaaaaaata ttgctgtagt tagagaactt
    11761 aaagagtatt tgatagctag tacagcattt attgttttgg atactttact taacgaaaca
    11821 tatttgaaat attatttatt atcagataat tttatcaatc gtgttaataa taaatctact
    11881 ggaacaagtt atcctgcaat caatgattat aattttaatc tattattaat tgctctcccc
    11941 ccactatccg aacaacaacg aata
//
LOCUS       DAVKBC010000048        11939 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVKBC010000048 DAVKBC010000000
VERSION     DAVKBC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.048"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            197..850
                     /locus_tag="VWX64_001717"
     CDS             197..850
                     /locus_tag="VWX64_001717"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU9191143.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            860..1324
                     /locus_tag="VWX64_001718"
     CDS             860..1324
                     /locus_tag="VWX64_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9191144.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTADLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1337..2605
                     /locus_tag="VWX64_001719"
     CDS             1337..2605
                     /locus_tag="VWX64_001719"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU9191145.1"
                     /translation="MLLIKNGHVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2619..2879
                     /locus_tag="VWX64_001720"
     CDS             2619..2879
                     /locus_tag="VWX64_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191146.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2890..4251
                     /gene="pdrM"
                     /locus_tag="VWX64_001721"
     CDS             2890..4251
                     /gene="pdrM"
                     /locus_tag="VWX64_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU9191147.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4405..5373
                     /locus_tag="VWX64_001722"
     CDS             4405..5373
                     /locus_tag="VWX64_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU9191148.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDFNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAIDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5389..6381
                     /locus_tag="VWX64_001723"
     CDS             5389..6381
                     /locus_tag="VWX64_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU9191149.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6600..7643
                     /locus_tag="VWX64_001724"
     CDS             6600..7643
                     /locus_tag="VWX64_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU9191150.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMNLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7707..9392
                     /gene="lpdA"
                     /locus_tag="VWX64_001725"
     CDS             7707..9392
                     /gene="lpdA"
                     /locus_tag="VWX64_001725"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU9191151.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGSASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDNIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9456..10445
                     /locus_tag="VWX64_001726"
     CDS             9456..10445
                     /locus_tag="VWX64_001726"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU9191152.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10510..11580)
                     /gene="xerS"
                     /locus_tag="VWX64_001727"
     CDS             complement(10510..11580)
                     /gene="xerS"
                     /locus_tag="VWX64_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU9191153.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLKSGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
BASE COUNT         3551 a         2234 c         2666 g         3488 t
ORIGIN      
        1 gataatcttc gaaagaggta gtaaaatgct taatgattta aaaagtaatt ataaaaaata
       61 gccagtcttt ataaactgta ttcacgtatt caaatcgtat atagtcgatt tattaaatct
      121 ttagataaat tgtaaaaagt ggtttccata gccacttttt gctataatag aggcagtaaa
      181 aatgaaggag tcagctatgg aacactcgtc ttggcatgct ttgattaagg cgcaattacc
      241 tgagggttat ttcgggaaaa tcaatcagtt tatggagcag gtctattctc aggggattat
      301 ttatccaccc aaggaaaagg tttttcaggc tctcttgaca acactgcttg aagaagttaa
      361 ggtggtaatt ctagggcaag acccctatca cggaccaggt caagcgcagg gcttgagttt
      421 ttctgtacct gactctatcc cagctccacc atccttgcaa aatatcttga aagaattgtc
      481 agatgatatc ggagttaaga aatctcatga tttgacagct tgggctgagc aaggagtctt
      541 gcttcttaat gcttgtttga ctgttcctgc tggacaggcc aatggtcatg ctggtcaaat
      601 ctgggagcct tttactgatg ctgtgattca ggtggtcaat catctagata gaccagtcgt
      661 ttttgtactc tggggagctt atgcacgtaa gaagaaggcc ttagttacca atcctcatca
      721 cttgattatc gaatcagccc atccaagtcc tttgtcggtt tatagaggat tttggggttc
      781 caagcccttt tccaaagcca atgcattctt aaaagagaca ggacaagagc caatcgattg
      841 gcttagataa ggagaaaata tgcctcagtt agcgacgatt tgctacattg ataatgggaa
      901 agaactgctc atgctccatc gtaataagaa acccaatgat gtccatgaag ggaaatggat
      961 tggtgtgggt ggtaagctag agagaggaga gacgccccag gaatgcgcgg cgcgtgaaat
     1021 ccttgaagaa acagggctca aagccaagcc agttctaaaa ggtgtcatca cttttcctga
     1081 atttacagca gatttagact ggtacaccta tgtttttaag gtgacggagt ttgagggcga
     1141 cttgattgac tgcaatgagg ggacgctaga atgggttccc tatgacgagg ttttgagcaa
     1201 gccgacttgg gaaggtgacc acacctttgt tgagtggctt ttagaggata aacccttctt
     1261 ttcagccaag tttgtttatg atggggataa attgttggat acccaagttg atttctatga
     1321 ataaaggaga aagcagatgc tactaatcaa aaatggtcat gtaatggatc ccaagtctgg
     1381 tttggatcaa gtttgtgatg tcttagttca agatgggaaa attatcaaaa ttgcgcctga
     1441 gatcacggaa gaaggagcag aaacgattga tgctactggt cttgtggttg ctcctggttt
     1501 ggtcgatatt catgtgcatt tccgtgaacc tggtcaaaca cataaagaag acattcatac
     1561 tggtgcccta gcagccgctg caggtggttt tactactgtc gtcatgatgg ctaataccag
     1621 tccaaccatt tcagacgtgg agactttgca agcagttctc cagtcagctg ccaaagagaa
     1681 gattaatgtc aagacagttg cgaccattac taaaaacttt aatggtaaaa acttgactga
     1741 ctttaaggcg ctcttagaag ctggtgcggt tggtttctct gatgacggta ttccgcttga
     1801 gagcagtaag attgtcaagg aagccatgga ggaagccaaa aaactcaata cctttatcag
     1861 ccttcatgag gaagatccag gtttgaacgg tgttcttggc tttaatgaaa atattgctag
     1921 agaacatttc catatctgtg gtgctactgg ggtggctgag tacgctatga tggcgcgtga
     1981 tgtcatgatt gcctatgcaa ctaaagccca tgttcacatc cagcatttgt ctaaggaaga
     2041 aagtgttaaa gtagtggagt ttgctcaggg gttaggtgca gaagtcacag cagaagtagc
     2101 accacagcat ttctctaaga cagaagcact tcttttaaca caaggtagca atgctaagat
     2161 gaatccaccg cttcgtttgg aatcagaccg tcgtgccgtt atcgaaggtc tcaaatcagg
     2221 tgtcatcaca gttattgcga ctgaccacgc gcctcatcat gtagatgaaa aaaatgttga
     2281 agatattacc aaagcgccat ctggtatgac tggcttagaa acatccctgt ctctcggctt
     2341 gacctatttg gtagaagctg gtgagttgag cttgatggaa ttacttgaaa aaatgacata
     2401 caacccagcc aagctttaca actttaaagc aggttacttg gctgagaatg gtccagcaga
     2461 tatcactatt tttgatgcca aggctgaccg ccttgtggac tcccattttg cttccaaagc
     2521 agctaattca ccattcatcg gtgaaacctt aaaagggcag gttaaatata ccatctgtaa
     2581 gggacaaatc gtctatcaag cttgatagga gttagaatat gaattatttt cgaaaacgta
     2641 gggagagaca agcgaaatct aatagtggaa tttactgtcc cgcagctaat cgttccaaaa
     2701 ttcaatatga aactaaagaa aaagctgacc atgcggttca atatgataac ggaggtttag
     2761 ttagaagcta ttattgtcgt acatgtgcgt gttggcatac tacttcaaaa tctaataaac
     2821 ctccgctaag tttgaaaaac tatggtctga aactctttgg tttagataaa tcagaataga
     2881 aagagaagta tgtataagac aaagtgttta cgagagaagt tagtattatt tttaaaaatt
     2941 ttcttcccaa tcctgatcta ccaatttgcc aattattctg cctcttttgt tgatactgca
     3001 atgacaggtc aatacaacac tatggacttg gctggtgtat ctatggcaac cagtatctgg
     3061 aatcctttct ttacatttct aacagggatt gtgtcagcct tggtgcctat cattggtcac
     3121 catcttggtc gaggcaaaaa ggaagaagtt gcgtctgatt tttaccaatt tatttatttg
     3181 gccttgggcc tatctgtggt cttgctgggg atggtacttt tcttggcacc aacaatcttg
     3241 aatcatattg ggttagaagc agcagtagcg gcagtagcgg ttcgctatct ttggttttta
     3301 tctatcggga ttatcccctt gttgctcttt agcgtcattc gttccttgct ggattcgctg
     3361 ggcttgacca aactgtccat gtacctcatg cttttgttac tccctctcaa tagcggattt
     3421 aactatctct tgatttacgg tgcctttggt gttccagaac tgggaggggc tggtgctggt
     3481 ttaggaacat ccttggccta ctgggtcttg cttgggattt ctgttctggt tttatttaaa
     3541 caggagaagc tcaaagcctt acaccttgag aaacgaattc cacttaatat ggataacatt
     3601 aaggaaggag ttcgtttagg tctgcctatt gggggaactg tcttcgcgga agtggctatc
     3661 ttttcagtgg ttggcttgat tatggctaag ttttcgtcct tgattatagc tagtcaccag
     3721 tcagctatga acttttcaag tcttatgtac gcctttccta tgagtatctc atcggctatg
     3781 gctattgtcg tttcctatga agtgggagcc aagcgatttg atgatgcgaa aacctatatt
     3841 ggtctaggaa gatggactgc tctcattttt gcggccttca ccctaacctt cctttacatt
     3901 tttaggggaa atgtggccag tctttatggt aacgacccaa aatttatcga tttgacagcg
     3961 cgttttttaa cttatagtct tttcttccag ttagcagata cctttgcggc accgcttcag
     4021 ggaattttgc gggggtataa ggatacagtt attccttttt accttggttt gcttggttat
     4081 tggggcgtag caatccctgt ggctacgcta tttgattccc taacagattt tggagcttat
     4141 tcttactgga tcggcttgat tattagtttg attgtgagtg gggcgctcta ccgttggcgt
     4201 ttaactgtga ttatgaagag atttgaatct ttagcaaaat ccaaacgcta aaaagtttgt
     4261 gaaaaaatat ccttgacaag aaaatccctt gttttcacgg ggttttcttt tttattttgt
     4321 gaaatttctt ttagaaaaac tttgacagta tttgccaaaa gcggtaaaat agtaaggtaa
     4381 gaagaaagtt agaaaggcaa gaagatgtca actttagata aaaatctttt gctagaaatg
     4441 ttccgtaaga tggaagaaat ccgtcgcatg gacttaaaaa ttgcacaatt agtaaagaaa
     4501 gggaaagtgc caggaatgac gcacttttct gttggtgaag aggcagctaa cgtgggggct
     4561 atgttagctc tcaatccaga tgatctgatt acctcaaacc accgtggaca cgggcaagct
     4621 attgctaaag ggattgactt caacggaatg atggctgaaa tccttggtaa atacactgga
     4681 acctgtaaag ggaaaggtgg atctatgcat atcgctgacc ttgatgctgg gaaccttggt
     4741 gccaatggta tcgtaggtgg tggtatgggg atcgctgtcg gtgcagccct cagtcagcaa
     4801 atgcaaaata ccggtaaaat cgttgtctgc ttctttggag atggtgcgac caatgaaggt
     4861 gttttccacg aagcagtgaa catggcttct atctggaacc tgccagtcat tttctattgc
     4921 attaacaacg gttacggtat ctctgcggat atcaagaaaa tgaccaatat agaacatatc
     4981 catcaacgta gcgccgctta tggaattcct ggaatgttca tcgaagacgg taacaatgtc
     5041 atcgatgtct atgaaggatt tcagaaagct atagaccatg ttcgcagtgg caatggtcca
     5101 gtcttgattg aaagtgtaac ttatcgctgg ctcggtcact catcatctga ccctggtaaa
     5161 tatcgtacgc gtgaagaagt ggaattgtgg aaacaaaaag atccaatcga aaacctccgc
     5221 aattacctta ttgaaaataa cattgcaagt gccgaagaat tggaagaaat ccaagcgcaa
     5281 gtaaaggaag cagtagaagc ttctgttaaa tttgcagagg aaagcccatt cccaccgctt
     5341 gaatcagcct ttgaagatat ttacgcagac taaggagaaa gagataaaat ggaaacaaaa
     5401 acaatgtcct tccgtgacac cattatcctt gctatgtctg aggaaatgcg tcgcgatgaa
     5461 aatgtgttct tgatgggaga agacgtcggt gtcttcggag gagacttcgg tacttctgtt
     5521 ggaatgcttg aagaatttgg tccagaacgt gtccgtgact gtccgatttc tgaagctgcc
     5581 atctctggag ctgcagcagg agcagccatg acaggacttc gtccaatcgt cgatatgacc
     5641 ttcatggact tctctgttat tgccatggac aatatcgtca accaagctgc taaaacacgt
     5701 tacatgtttg gtggtaaagg tcaggttcca atgactgttc gttgtgcagc tggtaacgga
     5761 gttggctctg ccgcccagca ctcacaatct ctagagtctt ggtttactca cattccagga
     5821 cttaaggttg tggcacctgg aacacctgcg gacatgaaag gcctgcttaa gtcttctatc
     5881 cgtgataaca acccagttat tatacttgag tacaagtcag aatttaacca aaaaggggaa
     5941 gtgccagttg atccagacta cacaattcca cttggggttg gtgaaatcaa acgccaagga
     6001 acggatgtaa cagttgtcac ttatggaaaa atgcttcgcc gtgtggttca agctgctgaa
     6061 gaattagctg aagaaggaat ttcagttgaa attgttgacc cacgtaccct tgttccgctt
     6121 gataaggata tcatcataaa ctcagtgaag aagactggta aggttgttct ggtcaacgat
     6181 gcccacaaaa caagtggcta tatcggtgaa atttcagcta ttatttcaga atcagaagca
     6241 tttgactatc tagatgcacc aatccgccgt tgtgcaggag aagatgtgcc gatgccttat
     6301 gcacaaaacc tagaaaatgc aatgattcca acagttgaaa gtatcaaaga tgcaatccga
     6361 aaaacttata acaaagaata gagtcacata agataagtta tgtaaataaa acaaagctga
     6421 cgagaaactt tgtatctttt aggtgcagag ctcttcgtcc ttaatatctt agattagagc
     6481 acgggctaaa agcttggaaa aaaagataaa tctccttggc ttcatcgaag ccatcgtcga
     6541 tttcctattt ttcagtcgct tttgacgccc tttgtatcat aaatagaatt ggagaggtca
     6601 tggctgatga caagctaaga gcgactcctg cagctagaaa gttagcggat gatttaggga
     6661 taaacctcta cgacgtttct ggctcaggtg caaacggtcg tgtccacaaa gaagacgtgg
     6721 aaacttataa agacacaaac gtggttcgca tttcgccact tgcaaaacga attgccctcg
     6781 aacataacat tgcttggcag gaaatccaag gaaccggtca tcgtggtaaa atcatgaaga
     6841 aggatgtttt ggccctgctt cctgaaaata tcgaaaacga tagcatcaaa tctcctgctc
     6901 agattgaaaa agtggaagaa gttcctgata acgtaacacc atatggtgaa atcgagcgta
     6961 ttccaatgac accaatgcgt aaggttattg cccaacgcat ggttgaatct tacttgactg
     7021 cgccaacctt caccctcaac tatgaagttg atatgactga aatgttggct cttcgtaaga
     7081 aggttcttga gccaatcatg gaagcaactg ggaagaagac tactgtaaca gaccttcttt
     7141 cgcttgcagt tgttaagact cttatgaaac acccatacat caacgcttca ttgacagaag
     7201 atggcaagac tattatcact cacaactatg tcaatcttgc catggcagtt gggatggata
     7261 atggattgat gacacctgtt gtttacaatg ctgagaagat gagtctttca gaactggttg
     7321 tagcctttaa ggatgttatt ggccgtacct tggatggtaa attggctcca agtgagttac
     7381 aaaattcaac attcacaatc agtaatttgg gaatgtttgg tgttcagtcc tttggtccga
     7441 ttattaacca acccaactca gctatccttg gtgtcagttc gacaatcgag aagccagttg
     7501 tcgtcaatgg tgaaattgtg attcgcccaa tcatgaattt aggattaacc attgaccacc
     7561 gtgtcgtaga tggtatggct ggtgctaagt ttatgaagga cttgaaagag ttgattgaaa
     7621 cgccaatctc aatgttgatt taagagcaag agtattcatt tttaagatat agataaagga
     7681 aggaagacat ggccttagaa gtaattatgc caaaagccgg cgtggatatg acagaaggac
     7741 aaatcgtcca atggaataaa aaagtcggag aatttgtaaa agaaggagaa atccttttgg
     7801 aaatcatgac tgataaagta agcatggaat tggaagccga agaagatggg tacttgattg
     7861 ccattctcaa aggagatggt gaaactgtcc ctgtaacgga agttatcggt taccttggtg
     7921 aagaaaggga aaacatccca acagctggat cagcatcgcc agaagctagc cctgtccctg
     7981 tagcaagtac ctcaaacgat gatggtaaga gcgatgatgc ttttgatatc gttgtgattg
     8041 gtggaggtcc tgctggttat gttgcagcca ttaaagctgc ccaactcggc ggtaaggttg
     8101 cccttgttga gaaatctgaa cttggtggaa cctgcttaaa ccgtggatgt attccaacca
     8161 agacctacct tcataacgct gaaattattg aaaatatcgg tcatgctgca aatcgtggta
     8221 tcgtgattga aaatcctaac ttcactgttg atatggaaaa acttttagaa actaaatcta
     8281 aagttgttaa tactcttgtt ggtggtgttg caggacttct tcgtagctac ggagttactg
     8341 ttcataaagg aattggtaca atcactaaag acaagaacgt cttggtaaat ggttctgaat
     8401 tgcttgaaac caagaagatc attcttgctg gtggttcaaa agtcagcaag atcaacgtcc
     8461 ctggtatgga atctccactt gtcatgacta gtgatgacat tcttgaaatg aacgaagtgc
     8521 cagaaagcct tgttatcatc ggtggtggag ttgtcggtat cgaactcggt caggccttca
     8581 tgacatttgg ttcaaaagtg actgttatcg aaatgatgga ccgtatagtt ccagctatgg
     8641 atgcggaagt ttctaagaac cttcgcttga tccttgagcg taaaggaatg accatcttga
     8701 ctggtactaa actgcaagaa atcattgagg aaaatggtca acttcgtatc aaggttgaag
     8761 gaaaagacaa tatcatcgca agcaaagctc ttctttcaat tggtcgtatg ccagaccttg
     8821 aaggtattgg agaggttgag tttgaattgg atcgtggttg tatcaaggtc aatgaataca
     8881 tggaaacttc agttccaggc atttatgcac caggtgacat caacggtact aagatgttgg
     8941 ctcacgcagc tttccgcatg ggtgaagttt ccgctgaaaa tgcccttaaa ggaaatcatg
     9001 cagttgccaa attgaatttg actcctgcag ccatctacac tctccctgaa gtagcagcag
     9061 taggtttgac agaagaacaa gcccgtgaga aatacgatgt tgccatcggt aagtttaact
     9121 ttgctgctaa cggtcgtgct attgcatctg acgcagctca aggtttcgta aaagttatcg
     9181 ctgataagaa atacggagaa atccttggtg tacacattat tggtcctgca gccgcagaat
     9241 taataaacga agcatcaagc atcatcgaaa tggaaatcac tgttgaggaa atgctgaaga
     9301 ccatccacgg acacccaact tactctgaag tgatgtacga agcgtttgca gatgttctag
     9361 gaatggccat ccattcacct aagaaaaaat aaaacgaaga tagattagac tggaaggtta
     9421 tttccagtct ctatcatata aagtaaaggg atatcatgaa atacattatc aatcattcaa
     9481 atgacactgc ttttaatatt gccttggaag aatacgcctt taaacacctt ttggatgagg
     9541 atcaaatctt cctactttgg attaacaagc catctatcat tgttggtcgt caccagaaca
     9601 ctatcgaaga aatcaaccgt gattatgttc gcgaaaatgg tattgaggta gttcgccgta
     9661 ttagtggtgg tggagctgtt taccacgatt taaataacct caactacacg atcatctcca
     9721 aagaagatga aaataaggca tttgacttca agagcttctc aactccggtt atcaataccc
     9781 tggctcaact cggggttaaa gctgagttca caggtcgtaa tgaccttgag attgatggta
     9841 agaagttctg tggcaatgcc caagcctata tcaacggccg tatcatgcac cacggttgct
     9901 tgctctttga cgttgatttg tcagtcctcg caaatgccct taaggtttca aaagataaat
     9961 ttgaatcaaa aggtgtgaaa tccgtccgtg cccgtgtaac caatattatc aatgaattac
    10021 caaaaaaaat cacagtcgaa aaattccgtg atttactcct ggaatacatg aaaaaagagt
    10081 acccagagat gactgaatac gtcttttcag aagaagaatt ggccgaaatc aatcgcatca
    10141 aggatactaa gtttggaact tgggactgga actatggtaa atcacctgaa tttaacgtcc
    10201 gtcgtggaac caaattcact agtggtaagg ttgaagtctt tgctaatgtt actgaatcaa
    10261 aaatccaaga catcaagatt tatggtgact tctttggtat tgaagacgtt gctgcagtag
    10321 aagatgtcct tcgtggggtg aaatacgaac gcgaagatgt tcttaaggcg ctaaaaacta
    10381 ttgatatcac acgctacttc gctggtatta gccgtgaaga aatcgctgaa gcggtagttg
    10441 gataaatcaa aaagaagttg gccaacttct ttttttgata tttatttaca taatttaaaa
    10501 tacgtaaaat cataaactat ccagagcatt cttttgttca tcactaacaa tatgggtata
    10561 gaggtcagtg acttgtgtgc tagcatgtcc tagttggtga ctgactaaaa cttgtgattt
    10621 agtcgcatca tagagcctag ttgctagtgt atggcgcagt ttatggggtg ttacacgcac
    10681 tttaaaatcc tctgagtatt tagcaaccat tttctcaacg ctagaagcat cgatacgatt
    10741 aggaacacct ctgtagagag ttaaaaaaag ggctgtatct gttttttccg ttttatagcg
    10801 ttgattccga atggccagat aattctctaa ataaggttta gcaaaagcag cgacattgac
    10861 tgagtcacgt ttgccacctt ttcgagtaac atcaataacc atcattttta gattgagatc
    10921 tcttagatct agattaacag cttcagataa gcgaacacca gatgccaaga gaagggcaat
    10981 aatggctaaa tctcgttctt tatttttgtt gaatgatgag agagctcgat ttgaaagctg
    11041 ttgtgggtgc tcttgatcga tataagttag aaaaccttct gtttcatcac ctagaaagag
    11101 tttttgcttg atattttcag ctctggcagc aagggtttct ttctttttct tggttgaaac
    11161 ttttttcatt acattacgat agaaataagg ttccccctga tcgttttcaa cctcctcggt
    11221 tagatacttg taaagactag aaagtgctga taaggttcga ttgatagttg tctgtgaaac
    11281 accctgtttt gttgtattag cattcagcaa gggacgttca cgtagataaa ggataaagga
    11341 ttccatgtct ttcttagaca tattttccaa aactgataaa ggaatatcgg atattttatc
    11401 agcgtttgaa ataccagact tcaaaaccca gctgaaaaat cggtcatatt ccttaaggta
    11461 ttcgtacagg gttgtaaaac tgtagggtac agccagctta gattggtagt attccagaac
    11521 ataccagggc atgagttgtt ttagtttgtc gattcgttcc agtaaaatct cacgtttcat
    11581 gtattttctc cataagtaag tatactagta gtatagcata gacttgtata tttttcaaga
    11641 aaattatagt ttttcagaaa gatgttatag gagtttttca aagtgataaa aacacttaga
    11701 cctacaaaca aaacagaata aggaaaataa tgaaaatctc acccactaaa cttctgttaa
    11761 tactacataa ctgaagagct atataaggag ctatgagata caaaacacat tgtataatag
    11821 attgaaacta gaatagtaca tctggacttc taaaacattg ctagaaattg atttgattgt
    11881 cctgattgtt ttatcctatt tctatttcat ttcactatat aattgctatt gttttcttt
//
LOCUS       DAVKBC010000049        11692 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVKBC010000049 DAVKBC010000000
VERSION     DAVKBC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.049"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..182)
                     /locus_tag="VWX64_001728"
     CDS             complement(<1..182)
                     /locus_tag="VWX64_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191154.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHT"
     gene            complement(497..1555)
                     /locus_tag="VWX64_001729"
     CDS             complement(497..1555)
                     /locus_tag="VWX64_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191155.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILLFVQ
                     SYLGSNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSKCMPSQYDR
                     FFYKDRPYIFSRKSSIKG"
     gene            complement(1712..1921)
                     /locus_tag="VWX64_001730"
     CDS             complement(1712..1921)
                     /locus_tag="VWX64_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191156.1"
                     /translation="MFFAGIGEIHFLLFLLYLSMSASPIIGLVIGYTKINLINSIIIA
                     LGMILALILVLSRVYRKYFYRDDDD"
     gene            complement(1939..2301)
                     /locus_tag="VWX64_001731"
     CDS             complement(1939..2301)
                     /locus_tag="VWX64_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU9191157.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGGVGCNWWNKRDNIAAAAVSGG
                     MSVYQTYAIKKLIANRGMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGA
                     IAYGLDIVDGKFDGYLWA"
     gene            2938..3801
                     /locus_tag="VWX64_001732"
     CDS             2938..3801
                     /locus_tag="VWX64_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9191158.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(4090..4878)
                     /gene="argH"
                     /locus_tag="VWX64_001733"
                     /pseudo
     CDS             complement(4090..4878)
                     /gene="argH"
                     /locus_tag="VWX64_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            complement(4938..6134)
                     /locus_tag="VWX64_001734"
     CDS             complement(4938..6134)
                     /locus_tag="VWX64_001734"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU9191159.1"
                     /translation="MSKEKVILAYSGGLDTSVAITWLKKDYDVVSVCMDVGEGKDLDF
                     IHDKALKVGAVESYVIDVKDEFATDYVLVAHQSHAYYEQKYPLVSALSRPLISKKLVE
                     IAHQIGATTIAHGCTGKGNDQVRFEVSIAALDLNLKVIAPVREWKWSREEEIYYAKEN
                     GVPVPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITTSPEQAPDMPEYIEI
                     EFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAV
                     TLLTAHKEIEDLTLVREVAHFKPIIENELSNLIYNALWFSSATQALIAYIKETQKVVN
                     GTAKVKLYKGSAQVVARKSPSSLYDENLATYTSADTFDQDAAVGFIKLWGLPTKVHSE
                     VQKSAK"
     gene            complement(6151..6957)
                     /locus_tag="VWX64_001735"
     CDS             complement(6151..6957)
                     /locus_tag="VWX64_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9191160.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(7164..7805)
                     /locus_tag="VWX64_001736"
     CDS             complement(7164..7805)
                     /locus_tag="VWX64_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191161.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            complement(7802..9910)
                     /locus_tag="VWX64_001737"
     CDS             complement(7802..9910)
                     /locus_tag="VWX64_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9191162.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPPLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(9962..10249)
                     /locus_tag="VWX64_001738"
     CDS             complement(9962..10249)
                     /locus_tag="VWX64_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU9191163.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            10680..11000
                     /locus_tag="VWX64_001739"
     CDS             10680..11000
                     /locus_tag="VWX64_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9191164.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(11053..11640)
                     /locus_tag="VWX64_001740"
     CDS             complement(11053..11640)
                     /locus_tag="VWX64_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9191165.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
BASE COUNT         3749 a         2485 c         1802 g         3656 t
ORIGIN      
        1 aaagtatgta agcattgaga caaaatatag aataacggta tcgccaatac aaaggttaag
       61 atggcatgag agggagttcc taagatgtcc aattttataa atactgggct gacacaaaat
      121 atcgtgctta taagcagtaa aattattaaa attgtgtcaa aaaaataacg cttatttttc
      181 atttagtcta ctttccattg ttaaataata ctactgctaa caccaagcca acttagcaca
      241 ttgcatcacc taatcctgcg ctacttgtcc ataatccttt aatgtttcta ctaaaattat
      301 tccaatctcc cccatcaaga tagcttattt atcctagaca acgcctactg caacagtata
      361 aataagattc atcagccatc ttttctggca atcatatggg tagcctaatg atatttctag
      421 ttactcaaaa atatctagct atactagagt tatttctaat ccctaggaca cttgttaatc
      481 caaatgtaac aaattttcac cccttaatag aactctttct ggaaaaaata taaggtctat
      541 ctttataaaa aaatctatca tattgggatg gcatgcattt ggaatttaaa caagctataa
      601 attcatttat aactactatt tgtttagagg caacagcatc ttgtataccg ccctcgaaag
      661 aaccatcttg taattccgaa atatttttgt ttaaatattg ttttgacaaa tctcttaatg
      721 cttcattatc gtaaatgatt cccaaaaatc caaccttata tagtaaataa tttaaactta
      781 caaagtaatt gaatcccata gtatattttt ctttataaag caaaggtaaa actttataaa
      841 aaatatctaa gtcaacctca ctctgattct gaagcaagta ggagtcaagc aaattttcaa
      901 aaatagctat caatatgatt ggtgtaaggt ttttgtattc acatgtcaag tattctgagt
      961 atcgtgcaga tgatatttct tttacataac tttttgaaag caagattttt tcaaattcat
     1021 catctattat taatcttcta tttccaatcc aagcggtatt gctacccaaa taagattgta
     1081 caaatagcaa tatgtaagag aacatgaacg taaatactga aagaggtaga attctatgcg
     1141 taaaaaaata gacgataatg gtagccagga gtaaagctat ctctcgtgac aatcgaattc
     1201 ttttcagcat cttttttaac agtccgtaag gttgtccttg gcaatattct tgaactaaat
     1261 taatcggaat gacatctctc accatttctg gaaagtagag taagtttata ggttgaaatc
     1321 tccagctccc atcataagta aatggatata gaaccaaata cttaaaagat ttttttctta
     1381 taaacttaat tatcacaata tgaatgactg ttgcaatgaa gtatattaaa tataaaagta
     1441 aaaccgccat caatatactt acaaaaatcc ccttggaatc aatcaatgga aaataaaata
     1501 ttgcaactag aagcgaataa agtcccgcta ataaatattt ctgatcatct ttcatttaaa
     1561 acaccatatt atttactaag aatgcatcaa tacaatagag caactctgta agtcaatatt
     1621 tgataaagca aagctttaaa cccttcccca gacgttagct tttattcaac ccactacagt
     1681 tgacaaggag cccaaattat tgataaaaac tttagtcatc atcgtctcta taaaaatatt
     1741 ttctatacac tcttgataat accaaaatta atgccaatat cataccaaga gctataataa
     1801 tagaatttat tagatttatt ttagtatatc caatcactag tccaataatt ggactagcag
     1861 acatgcttag atataataaa aataacaaaa aatgaatttc accaattcct gcaaaaaaaa
     1921 tgtttcatag ctatagtttt acgcccataa atacccatca aatttaccgt ctacgatatc
     1981 taaaccatat gcaatggctc ctcctaatga gaagacttca gcaacagtag ccgcaatatt
     2041 aagagcatta gtaatagttg ccatactaac tccaccaata tatcttgtta tagcacttct
     2101 aacgactcgg ctcatcatac cacgattagc aattaacttt ttaatggcat atgtctggta
     2161 tactgacatc cctccagaaa ctgcagctgc agcaatatta tcacgtttgt tccaccagtt
     2221 acaaccaaca ccacccccat caagatacat catctcttct tgctcaagaa caacataatt
     2281 atttggtaat acgagttcca tttattttct ccttttttat taagcatggt taggatggtt
     2341 tcctaacaag tgatcgcagg ctttgtttag ttacctaaat tagacttcct tcctttatct
     2401 tattttaaat atttaaaacc agttactgct tgaagcttaa cagtttactt aattcaaata
     2461 acagctaatc actgattccc tgattttatc aaatatacta ataacaacaa ttgtgatacg
     2521 atcatcatta taagaacaac atttaacgaa tcaaagtttt tccgagataa taataaagca
     2581 acagcaagca gtattattac taaagattga ataactacta ttactcttaa cattttatcc
     2641 tctactaaca actcaagctc ccttacatta tatcgaccag ccccatggaa agattatagc
     2701 cagactaatc aataatataa tacatactag aatacaaaat atttttttat tcatactttt
     2761 tctcctatct ttattttcta cctacatagt acctcttatt aagctcattt taaaattacg
     2821 ttaacttttt tcacaaattt atttcgactt tcttttttac tttttacatt gctatgatac
     2881 aatattttta acaaaatttt attgtttgtt aacttttttc acgaaaagga gaaaatcatg
     2941 cgttatgatt tcggaaaggt ctataaagaa atacgtgagt caaaggggct gacccaagaa
     3001 gaggtctgtg ggggtgttct ctcaagaacc agcttatcaa aaatcgaaag tggcaagaca
     3061 accccaaaat atgaaaatat ggaatttctt ctccgtcaaa tcaatatgag ttttgaagag
     3121 tttgaatata tctgtcaact ttatcaacca agccaacgca cagagattat gcaaacctat
     3181 ctcaatatgc gttccattat cgggaccagc gatcttgtca atttatttca aaaatgccaa
     3241 gactacctca agacccacca cgatctccct atagaagaaa tcagagatat gcttgaagtt
     3301 gttatttatc tccgtcaaca cggggcaggg gaactatcaa aacacgcaga acaggttgtc
     3361 aaaaaacttt ggaaaaaaat tgaaaaacaa gatacatggt atgagagtga tctaaaaatc
     3421 ctcaatacca ttcttttcag ttttcccatt gaatacctcc atctcatcac tggaaaaata
     3481 ttgcaacgcc tagaagtcta taaaaactat caacatttat atgacttgcg aatgacaatt
     3541 ctattaaacc tttccacact ctatctatac aatcaagata aaaacatgtg taagcaaatc
     3601 tgctacactt tactagagga cgccaagaat aagaaaagct acgataggct ggctatctgc
     3661 tatgtccgta ttgggatttg tacagacgat tctaaactta tccaaaaagg gttctccctt
     3721 ctggagctaa ccgaggaaac ttctatgctg tctcatctca aaaaagaagt agagatctat
     3781 taccaagcga aggaaagata aaaaagccga gggatttcct cgactcttta catattattt
     3841 gttcgttagt tcttaatacc agccattgtt aagccagaag tttttagctc tgccaagcca
     3901 catagtgtgt ttactactat gtgtccctgt caccatgaat cgccgaacga tttaacgaga
     3961 aagtatgact tttacgttta tcccaactca attatgacat ttttttcaaa agtcaatata
     4021 tctcactttt tcaacgataa gaaagaggct gccaatcgac caacctctta ttctgaaccc
     4081 atcactccat cactttttag cttcattcgc tttcttagcg actgcaatct ggtattcgac
     4141 ttggtcaaac cctgtgcctc ccaaggaatt tcgtctttga acagcagttt taggttgcaa
     4201 gtagacatag atatcctcgg taatgagaga atgataggtt tgtaattcct ccaaagtcca
     4261 atcttgaaga tttttagcag acttgataga gtctagcact aatcttccca caacctcatg
     4321 agcttctcta aatggcaagc ctttccctgc caaataatct gccaactcag ttgcatttga
     4381 aaagtccttc tctgttgatt cttgcatttt ttccttgttt acctgcaaac tagataacat
     4441 acctgccaac acatcgaggg aatttaaaat cgtttcgacc gtatcaaaca ttccttcctt
     4501 atcttcttgc aaatccttat tataagctaa aggcaaggac ttcatgactg tcaacagtcc
     4561 aaacaaatgc ccataaactc tgccagtctt tcctcgaatc aactcagcca tatctggatt
     4621 tttcttttgg ggcataatag aggaacctgt tgtaaacgta tctgacaagg taatgaattg
     4681 gtactcaaaa ctacaccaat tgatcatttc ttcgcaaaaa cgactcatat gcatcatgag
     4741 tatgctggca tttgatagaa attctaagat aaaatcgcgg tcactaacag catccaaaga
     4801 atttgtataa ggttgcttaa actccagcaa atcgctagac aattggcgat caatggggaa
     4861 agtcgttcct gccaaagcga ccaccccata attttgtatt cttagccata tcacatccac
     4921 ctctctatcc aatcgtccta tttggcgctt ttttgaacct cagaatgaac cttggttgga
     4981 agtccccata acttaataaa gccaacagcc gcatcttggt caaaggtatc tgcactagta
     5041 tacgtcgcca aattttcatc gtaaagagaa cttggtgatt tccgagccac gacctgagcg
     5101 ctccccttat acagtttgac ttttgcagtc ccattgacaa ctttttgagt ctctttaata
     5161 taagcaatca aggcttgtgt agccgaacta aaccacaaag cattataaat gagatttgat
     5221 aattcatttt ctatgattgg tttaaaatga gccacttctc tcacaagcgt caagtcctca
     5281 atttccttat gagctgtcag cagggtcact gcacctggac actcatagat ttctcttgat
     5341 ttaatcccaa ccaagcgatt ttccacgtgg tcaatccgtc caaccccatg ttttccagct
     5401 atttcattga gtttttgaat caaatctgcc aattttaaca cttctccatt gagggaaact
     5461 ggaacacctt cactaaactc aatctcaatg tattctggca tatctggagc ttgctctgga
     5521 gaagttgtga tgccaaaggc ttcttctgga gcctgattcc atggattttc caaaatacca
     5581 cactcattgg cacgtcccca aagattttgg tcgacagagt agggattgtc aaggtcagca
     5641 ggaacaggca ccccattttc cttggcataa taaatttctt cctcccgaga ccatttccat
     5701 tcacgaactg gagcaatcac ttttaaattg agatccaagg ctgcaatcga tacttcaaaa
     5761 cgtacttggt cattcccctt accggtacaa ccatgagcaa ttgtagtcgc tcctatctga
     5821 tgcgctattt caaccaattt tttagaaatc agagggcggc tcaaggcaga taccaaggga
     5881 tacttttgtt cataataggc atgtgactga tgagccacta gcacataatc tgtagcaaat
     5941 tcgtccttaa catcaatgac ataagattct actgccccaa ccttaagagc cttatcatgg
     6001 atgaaatcta agtctttccc ttcacccaca tccatacaaa ctgaaacaac atcatagtct
     6061 ttctttaacc aggtaatagc aactgatgtg tccaaaccgc cagaataggc caaaattact
     6121 ttttctttac tcatgttcct ttccttcttt ctatttttca atggatgctt taaaggcatc
     6181 ctcaatgagt ttgtctaatt ccccagactc cttcaacttt tgaatggttt tatcgactgc
     6241 ctctttcaat tccttgctat cttttttcat ggctaccgcg taggaatcat cttgctcttt
     6301 ttcaaaattg aggtctgcga ttgctaaatc aggattattt tccacaaatc ccttggcaac
     6361 gggttcttca aaaataacgg catccacttg ccctgatttt aaatctgtga ttaaattccc
     6421 atttttaggc agagatacga gggaagaatt ttgtagcaaa tctttcgcca tcgtctcttg
     6481 aatcgaacct ttctgcgctc cgaccttttt ctgcgccaaa tcgttgacag actgataagt
     6541 ggctaaatca gattttttga caatgagttt attttttgca gtatagtagg gagttgaaaa
     6601 atcaaacacc ttgctccgtt catctgtctt agaaacacct gatatggcaa ggtcagcttt
     6661 tcctgattga acgctagcca gtacattgtc aaaactcata ggagatagtt ccaattcgac
     6721 acctagttct gttgcgatag ccttggctaa ttcgatatct gaacccacaa tctgattttt
     6781 cccatcaacc actttttgat attcaaatgg agcaaaatct ggattgaggg ctacaaccaa
     6841 ttttcctttg gacttgatgg cttcaattcc agccgattga ttgttactac aagcaaatag
     6901 tagggggagc atcactaaac caaacatcgt catcaacacc ttcttcatct tattcataac
     6961 aaagccttct ttatgtttat tcttttttat tgtataaata atacccctat actcatcctt
     7021 tgtcaagcct aaattgaaaa aattttcaat ttgaaacaaa aaaaacctaa aaatgctaca
     7081 taaaatgtca ttcctaggcg tatttatgct atttttctct ggaaaacatg agtattcagc
     7141 cagtcaaaag gagctgaatg aactcatttt ccctcgccca attcaatgat tcgatgacat
     7201 tgttgggcta cataagcatc gtgggtcaca ataatgactg ttttcccttc tcgattcatc
     7261 tctaagagaa acttcaagac caaatctcta ttttcaggat ccagcgaacc tgtaggttca
     7321 tcggctaaaa tcagctggct gggttttaag atggctctag caactgcaat tcgttgttgt
     7381 tcgcccccag acaactcgga gaccctttga tgcaaagtag ctgacaaacc tactctctct
     7441 aaaatctctt ccaccttttt gagcttgtct ttcttaggca atttcacata tttcagcgcc
     7501 agcatgagat tgtactcgac cgtttcatca tcaatcaggg caaaattttg aaacagataa
     7561 gagatatgtt cacggattat tgtttgcgac ttagcagaat taaccgctag atttgtctga
     7621 ccaaaaatct cataccgtcc gctataatca ccatctatca aacccaataa atttaacaag
     7681 gtcgacttcc cactaccact cttaccaaca atagctacca aatccccctg atcaatcctg
     7741 agagataagt tatccaaaat cacttttccc ccaatggttt tggtaatatt tttcaactca
     7801 atcataagat gccccctttc aataactcta ctagacttct tttctccatc ctagaagcta
     7861 agcctagcac aaatagtata tccagacatg taaaacctgc aaacagtaga ggtggtaaga
     7921 acgcatgggc aaagaaaatc aagactagaa gagggaaact atagcccagc aagagcagaa
     7981 cgaggagagg acggtagcga tcgaccagtt tccaccccat aaacttcttg gtaatgatat
     8041 ccctgcgctt caataagaaa gttgttacta gtaagaagta ggaaatcatc atgctaagga
     8101 gaccaaacaa agcaaagagt aggttaaaat tccgaacagc atctctataa gaatccactt
     8161 tctcttgttg aatggcttga atagatgaaa attttaaata atttccatct gacaatttct
     8221 caactaactc tgtaatctct ttttgatgtt gaaccgtatt ttcaatttta atcggattat
     8281 ttaagccagt tgttgacagg gaggctttct catcccacat catatcagaa tcattgacca
     8341 agctaataat tggattggag agattttcct ttcgcttatc actatatggg aaaaatgacc
     8401 aatctccttc ataataggca atctcgacat ccatctcctc tatcgttcgt ttttgctgct
     8461 cttcatactt catcgaatga aaggcaatta acttccccaa gagctgattt ttatcttctt
     8521 cacctttcgt acttgctggc atcaaaataa cttttttaat accggtatct ggtagcttga
     8581 atcccttgct ctttagaaaa ttgcgattgg catagtaaac atccaccgta tctgttaact
     8641 gatattgctg aatctgttct gattggacaa aattttttac aggaagactg ctactctgca
     8701 catagcccgc ctgcgttttt tctaccaaat cctgataaaa tcgatagaaa taatctgtag
     8761 atttccctga ccctgctagc tcttcttgcc acagattatc attgagtttg aaggtttcta
     8821 aggtcaggta attaccttga cttacccact gttgctgata agcaagttct ttgttttctt
     8881 gttctaaact tctgcccacc ccaatcagta aggccgtcag taaaatagtt gtccctattt
     8941 tcatcacata attgaagata agaccaaatt tgaaagatga aaaacctttc agcagagagc
     9001 tgattgtcat tttttggatt aagaggtaag tcaaccaact gataaagaga taaagctgca
     9061 acagcaaaaa atgagacaac cacagcatag gaaacaaatc ttttggctta taatcaagca
     9121 agaaaaacac gcctagattg atcacaagag ccccacctag gaggaggtaa aggttgcctt
     9181 ttacaacatc agctaaaaca gccctatctt gaaaaccaag taatttttgt accccaactc
     9241 ttttcatctc catcatcggt tgatacactg tcactaacac aagaagcaaa atagccaaga
     9301 caaaaacaat ggcagataaa agcaaatctc gatttatgac ttccactgca cttttgtagg
     9361 tcggctctag caaggtagcc tggtctatct tgaaaaaatc gctccatttc tgtacaatcc
     9421 tatccttgtc catctcttgt gtagaagtta tcgtatagcg accatttaaa ctacgagatg
     9481 tatccttgat ataggtttga aaagtcataa gctgaatagg tttggctttt agaaaggtcg
     9541 gaatcgtacc aagtttattg gaaatttctt tattactata gactccttca ccatctgtgg
     9601 taaaatcaag agaagaaatc ccaaactctt ggtaggggaa ggtatcttta tcaaaaacac
     9661 cagacttgac cacctcatca ccactgtctg ttttgatgat ggagacttta tactcctttg
     9721 atacatcctc aaaaaatcga agaacagacg ctgcaggttc gttaatatct ttcaaataca
     9781 aatccaaaga atctacagtc tttcccattt cttgaatccg aaccacttct cgtgtatagt
     9841 ttacattaaa aacaaaaaaa gtggtacaca gaagcaggag taacatacag aaattactga
     9901 tttttttcat aaaagtgcct ccactacagt tttccctctc caaataggag agggaagaat
     9961 tttactcaaa tccatagaaa tattccattc ctgttggcgg aatcttggtg agggaagctc
    10021 tagcccatgc ctcaggtttt gcataatcct tagaggttct acccccatgt ctaacagttg
    10081 ctgtatgata tcgagtagaa tgtaagtaat cagaatatcc aaaagttcct gtccaaccta
    10141 ctccatagtt ccattgacca ccctcaaccc atactgctaa agcatttgta gtagcaagta
    10201 taccacatac cattaaagat gcaacaccaa ttttaactaa ttttctcatg atttatttct
    10261 cctattatcg agagctgttc cgtaaaaaca gctatagtaa tttatcaaca agtatcgtag
    10321 tccattggac tcaccttcct tctatctcat ttcattttta aacaacgaac ttactcttaa
    10381 ctaggagaat agttctcttc tgtatcaggt ctttgaacaa ccagagtagt attaatcaca
    10441 ctctgactat tactcaagaa tcagcccaat aaacaacatg gatagcgctt tcaaattttt
    10501 aaaatcctat cccgtccttt tatctatata ataagcataa gcgaaaatat aataactgtc
    10561 aagtatctga agtgaatttt ataaaaaaat tacaagccaa atttgtaaag tttacactaa
    10621 gccgctaggg caatcgtcta tcagaatgtc cgtttatttg tcaataatcc gagaaaatct
    10681 tgcaacgctt agaagtctat aaaaactatc aacatttata tgacttgcga atagcaatcc
    10741 tgctcaacct ttccacactc tatctataca atcaagataa aaacatgtgt aagcaaatct
    10801 gctacacttt actagaggac gccaagaata agaaaagcta cgataggctg gctatctgct
    10861 atgtccgtat tgggatttgt acagacgatt ctaaacttat ccaaaaaggt ttctcactcc
    10921 tagagctgac cgaggaaact tctatgctgt ctcatctcaa aaaagaagta gagacccatt
    10981 atcaaccaaa gaaattataa aaaaagtcga gggagctcct cgacctttta catattattt
    11041 gttcgttagt tcttaatacc agccattgtt aagccagaag tttttagcag cagtccatga
    11101 accgtaacgt cctgcaacgt aggcatctgc tacacgttct tggttttcag ctgagtagtc
    11161 accgttcagg tatgaatctg ttaattggta acgtccgata taacgtccat ttgtagctgt
    11221 atagctacca cctgattctt tttgagcgat ccattctttg gcttctgctt cagatccgct
    11281 tacagttgaa acaactgttt cacttactac tggagtttct gctactggag ctgaaacagt
    11341 ttcatcttga gcggctggtg ccgcataagt agctggcgct ggtgttgcaa caggcgctac
    11401 agggccatcg ataaccaact cttgatcaac ataaatcaaa tgaatgttat caatgtggtt
    11461 gttttctgcc aatttttcaa ctgttgtgtt gtgagtttca gcgatttctg aaagtgtatc
    11521 accttcttta acagtgtaag ttgatgattc ttgagcagat acaaatgatg gagcaaatac
    11581 tgcaaacaag gcagctactc ctgcaagagt tgctttaatc tttttagtta ttgatttcat
    11641 attcgaaaat tctccttctt tctatagttc tatcataccc tttaaatatt ac
//
LOCUS       DAVKBC010000050        11163 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVKBC010000050 DAVKBC010000000
VERSION     DAVKBC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11163
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.050"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            97..477
                     /locus_tag="VWX64_001741"
     CDS             97..477
                     /locus_tag="VWX64_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191166.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGSFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPYVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            683..961
                     /locus_tag="VWX64_001742"
     CDS             683..961
                     /locus_tag="VWX64_001742"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191167.1"
                     /translation="MRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKLKEST
                     QKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            1012..1704
                     /locus_tag="VWX64_001743"
     CDS             1012..1704
                     /locus_tag="VWX64_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU9191168.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1757..4168
                     /locus_tag="VWX64_001744"
     CDS             1757..4168
                     /locus_tag="VWX64_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU9191169.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GSERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDENLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKISTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4418..5119
                     /locus_tag="VWX64_001745"
     CDS             4418..5119
                     /locus_tag="VWX64_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191170.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPAQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5121..7829
                     /locus_tag="VWX64_001746"
     CDS             5121..7829
                     /locus_tag="VWX64_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU9191171.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMETTANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ANVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQIGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7925..8416)
                     /gene="tpx"
                     /locus_tag="VWX64_001747"
     CDS             complement(7925..8416)
                     /gene="tpx"
                     /locus_tag="VWX64_001747"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU9191172.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8539..9468)
                     /gene="psaA"
                     /locus_tag="VWX64_001748"
     CDS             complement(8539..9468)
                     /gene="psaA"
                     /locus_tag="VWX64_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU9191173.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9500..10348)
                     /locus_tag="VWX64_001749"
     CDS             complement(9500..10348)
                     /locus_tag="VWX64_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9191174.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10345..11067)
                     /locus_tag="VWX64_001750"
     CDS             complement(10345..11067)
                     /locus_tag="VWX64_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9191175.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKTKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3282 a         2067 c         2537 g         3277 t
ORIGIN      
        1 tatacaaatt tttattttat aatatcagaa aatacttttt ttaaaagcaa atatgataca
       61 attttatttg aaaaaaataa aaaaggagat tttattatga aattaaaaac acttgcttta
      121 attagtggta tcgtcggtct tgtgggagga attttacttc ttattggttc ttttgtcttg
      181 ttgggaacag cggtaaatac agctgctaca actcttaatg gaggagctac tgcaggggct
      241 ttttcaggtg ttgccttact cttgaatgcc ttgaagattg caaatcttgt tcttggtatc
      301 attgctattg tttactataa aggagataag cgtgtaggtg cagctccgta tgtactaatg
      361 attgtttctg gtggagttag tctcattcca ttcttaggat gggttggggg gattcttgct
      421 attatcggag gatctctgtt ccttgcaaca ttgaagaaat tcaaatcaga agaataaaag
      481 gtattttagc atgaaaagaa caaaaaagtt tatcggtata ggagtagctc tattatctct
      541 ttctcttcta gttgcatgtg gaacataaag ttcaaagaat acttcaacaa gtaatgatga
      601 gaagacagta gcaacatcca atagttcaaa agaaacaatc actttcgata caccggttgt
      661 aacagacgat gcgattgaat caatgcgcac ttatgcagat tatatagatc tttataaaaa
      721 tatttttgat gattatttta ctaaagctga ggaaggtttc aaaggcacag ctatggaaaa
      781 taatgactcg tttactaaac taaaagagtc aactcaaaaa ttattcgatg cgcagaaaaa
      841 aaggttaaat aatgaagata gaatagaaac aaccaaaaac aatgtgattg ccaaacattg
      901 tcaaacagtc ctttcctttt tggttttgac tagctttttt gtgaaaaatt gtgtaaaata
      961 gaatagataa acgaggggaa acctcggaaa atttaaagga gaatccatct aatggtaaaa
     1021 ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag ctaacctttt cactggttgg
     1081 gctgatgttg atttgtctga aaaaggtaca caacaagcga ttgacgctgg taaattgatc
     1141 aaagaagctg gtatcgaatt tgaccaagct tacacttcag tattgaaacg tgctatcaaa
     1201 acaactaact tggctcttga agcttctgac caattgtggg ttccagttga aaaatcatgg
     1261 cgcttgaacg aacgtcacta cggtggtttg actggtaaaa acaaagctga agctgctgaa
     1321 caatttggtg atgagcaagt tcacatctgg cgtcgttcat acgatgtatt gcctccaaac
     1381 atggaccgtg atgatgagca ctcagctcac acagaccgtc gttacgcttc acttgacgac
     1441 tcagttatcc cagatgctga aaacttgaaa gtgactttgg aacgtgctct tccattctgg
     1501 gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg tattcgtagg agctcacggt
     1561 aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt cagatgacga gatcatggac
     1621 gtggaaatcc ctaacttccc accattggta ttcgaattcg acgaaaaatt gaacgtcgtt
     1681 tctgaatact accttggaaa ataaaaaatt gtaagcctag gattgatttc taggcttttt
     1741 atgttagtat ggaagtatga taaggaataa aaaacaagat tatgtactgg cctacaagca
     1801 accagcttca accacttaca tgggttggga agaagaagct ttaccgatag gtaatggttc
     1861 tttaggagca aaagtatttg gccttatagg gtctgaacgg attcaattta atgaaaaaag
     1921 tctctggtct ggaggtccac ttcctgatag ttcagattat cagggtggaa atcttcagga
     1981 tcagtatgtt tttttagctg agattcggca ggctttggag aagagagatt acaatctggc
     2041 taaggaactg gctgagcagc acctaattgg gccaaaaacg agtcaatatg ggacctatct
     2101 gtcttttggg gatattcaca ttgagttcag ccagcaaggt acgactttgt ctcaggtgac
     2161 ggactatcag agacagttga atattagtaa ggcacttgcg acgacttctt atgtctataa
     2221 gggaacgcga tttgaacgtg aagcttttgc gagttttcca gatgatctct tggttcaatg
     2281 ttttactaag gaagggttgg aaactctaga ttttactata gaactatcct tgacctgtga
     2341 tttggcttct gatggaaagt atgagcagga aaaatctgat tacaaggagt gtaagttgga
     2401 tattactgat tctcatatct tgatgaaggg aagagttaag gataatgatc tgcggtttgc
     2461 tagttatcta gcttgggaaa cggatggaga tattagagtt tggtcagata gggttcagat
     2521 atcaggagcc agttatgcca atctcttctt ggccgctaag acggattttg cccaaaatcc
     2581 tgctagcaat tatcgcaaga aactagattt agagcaacag gtgatagact tggtggacac
     2641 agctaaagaa aagggctata cccaattgaa atcaaggcat atcgaggact accaagcctt
     2701 attccagcgt gttcaattgg atttggaagc tgatgttgac gcatccacta cagatgattt
     2761 gttaaaaaat tataagccac aagaagggca ggctttggag gagctgttct tccagtatgg
     2821 acggtattta ttgattagtt cgtccagaga ctgcccagat gctctaccag ctaacctaca
     2881 gggagtctgg aatgcggtcg acaatcctcc ttggaattcg gactatcact taaatgtcaa
     2941 tctgcagatg aattattggc cagcctatgt taccaatctc ctagagacgg tctttccagt
     3001 catcaactat gtagatgatt tgcgtgtcta tggtcgtcta gcggctgtaa agtatgcagg
     3061 aatcgtctct cagaaaggtg aggaaaatgg ttggttggtt catactcaag cgactccctt
     3121 tggttggacg gcacctggtt gggattacta ttggggttgg tcaccagctg ccaatgcgtg
     3181 gatgatgcaa accgtttatg aagcctattc attttatagg gaccaagact atcttaggga
     3241 gaaaatttat cccatgttga gggaaacggt tcgtttttgg aatgcctttt tacataagga
     3301 tcagcaggcg cagcgttggg tgtcttctcc gtcttattct ccagaacatg ggccgatttc
     3361 gattggcaat acctatgacc aatctctgat ttggcagtta tttcatgatt ttattcaggc
     3421 tgctcaggaa ttgggactgg atgagaactt gttgactgag gttaaggaga agtctgattt
     3481 actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg gagtggtatg aggaggaaga
     3541 gcagtatttt caaaatgaga aagtggaggc ccagcaccgg cacgcttccc atctagtggg
     3601 actctatcct ggcaatctct ttagctacaa gggacaagag tatattgaag cggcgcgtgc
     3661 tagcctcaat gatcgtggag atggcggcac aggctggtcc aaggctaata agatcaatct
     3721 ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta ttggcagagc agttaaagat
     3781 atccaccttg ccaaatcttt ggtgtagcca tcctcctttt cagatagatg gtaattttgg
     3841 tgctactagt ggcatggcag aaatgttact ccagtctcat gcagcttatc tggtacctct
     3901 agctgcccta cctgatgctt ggtcaacagg ttctgtttca ggcttaatgg cacgtggaca
     3961 ttttgaagtg agcatgagct gggaagataa aaaactctta cagttgacca ttttatcaag
     4021 gagtggagga gatttgcgag tttcttatcc agatattgag aagagtgtga ttaaaatgaa
     4081 tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt atttcggtgg caacagcaga
     4141 aggtgatctt gttcaatttt atttttaaga agatgttata aggcagtaat ttgaaactgc
     4201 cttttaataa ggatttaaga atataggcag tttccaacta gttgaaaaag cgttataatg
     4261 ataataggaa gtaatactca atgaaaatca aagagcacaa actaggaagc tagccgcagg
     4321 ttgctcaaaa cagtgttttg aggttgtaga tggaagctga cgtggtttga agagagattt
     4381 tcgaggagta taatttgttt gatagagggt gggtctgatg gcttatattg agatgaaaca
     4441 ctgttacaag cgttatcagg ttggggacac ggagattgtg gccaatcgtg atgtgaattt
     4501 tgagattgaa aagggggagc tggttattat ccttggtgct tcaggtgcag gcaagtcaac
     4561 agttcttaac cttcttgggg gaatggatac caatgatgaa ggggaaatct ggattgatgg
     4621 tgttaatatt gcggattata gttcccacca gcgcaccaat taccgtagaa atgatgtggg
     4681 gtttgttttt cagttttata atctagtttc taatctgaca gctaaggaaa atgtggaact
     4741 ggcttctgaa attgtgacag atgccttgaa tcctgctcag gttttgacag atgtaggtct
     4801 ggctcatcgt ctcaataact ttccagccca gctttctgga ggggagcaac agcgagtctc
     4861 cattgcacgc gcggtagcca aaaatcctaa aattcttctt tgtgatgaac cgactggagc
     4921 cttggattat cagacgggca agcaggtttt gaaaattctc caagatatgt ctcgtcaaaa
     4981 gggagcgacg gtgatcatcg tgactcataa tggagctttg gcgcccattg ctgatcgcgt
     5041 gattcatatg cacgatgcca gtgtcaagga tgtggtgctc aaccagcatc ctcaggatat
     5101 tgacagtttg gagtactagc atgatcaagc gaaaaactta ttggaaggac ttaattcagt
     5161 ccttcacagg ctccaagggg cgttttttat ccatcttgat cctgatgatg ttgggatctc
     5221 tagccttagt aggcctcaaa gtaaccagtc ccaacatgga gacgacagct aatgcttatt
     5281 taacaactgc tcaaaccttg gatttggcag tcatgtctaa ctatggcttg gatcaagcag
     5341 accaagaaga actaaaacag acggagggcg cagaggtcga gtttggctat ttgacagatg
     5401 tgactatgga taatgggcag gatgccattc ggctgtactc caaaccagag cgaatttcaa
     5461 cctttcagct aagaaaggga cgacttcctc agtcagacaa ggaaatcgct ttggccactc
     5521 atttgcaagg ccaatacagc gtgggacagg agattagttt taaagaaaaa gaagagggtc
     5581 attcctcttt aaaagaccat acttatacca ttactggttt tgtggattcg gctgaaatcc
     5641 tctcccagcg agatatgggc tacgcaggaa gtggaagtgg gactctgaca gcctatgggg
     5701 tgattttacc tagtcaattt gatcagaaag tctacaatat agctcgtttg aaatatcaag
     5761 atttagcagg tttaaatgcc ttttcatcag cttatgaaga aaaatccaag caacatcagg
     5821 aagagcttga acaaatttta tcagataatg gcaaggtacg tctgcaactt ttgaaaaaag
     5881 aaggacaaga gtctctagac aaggggcaag agacccttga caaggctcag actaatttgc
     5941 aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat acaggctcaa gaaagtcaac
     6001 tagccttgtt tcctcaagtt cagagagagc aggctagtgc tcaacttacc caagccaagc
     6061 aggaattggg caaggaagag gccaaactaa agcaagctga acaaaatcta gcccaagaaa
     6121 aggaaaaatt agaaaaacat cagcaagtct tggacgattt ggcggagcca aggtatcagg
     6181 tctataatcg tcagaccatg ccaggtggtc agggctatct tatgtatagc aatgcttcat
     6241 ccagtattcg agcagtgggc aatatctttc ctgtggtact ttatgccgta gcagccatgg
     6301 tgacctttac gaccatgact cgctttgtag acgaagagcg aactcatgca gggattttta
     6361 aggccttggg ttatcgtagt aaggatatta tcgccaagtt tctcctttat ggactagtag
     6421 ctgggactgt cggaacggct ctaggtagta tacttggtca ttatttgcta gccaatgtaa
     6481 tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac tcagattcag ttctattgga
     6541 cctatagctt actagctctt gtcttgagct tgttggcgag tgtgttacca gcctatctgg
     6601 tggcttggag ggaacttcat gacgaagcag cccagcttct acttcctaaa cctcctgtca
     6661 aaggagctaa aatattattg gagcgtatcg gttttatctg gcgtcgtctc agttttactc
     6721 ataaggtaac agcccgcaac atctttcgtt ataagcagag aatgttgatg acaatctttg
     6781 gtgtggcagg ttctgtagct ctgctctttg caggtttggg aatccaatct tctgtagcag
     6841 gagttccgtc taaacagttt caacaaatcc aacagtatca gatgcttgtc tctgaaaatc
     6901 ctagtgcgac caatcaggac aaggtagagc tagcagaagt gttgaaaggg caggagatac
     6961 tagcctacca gaaaatctat tctaaaacgc tagacaagga tttcaaaggc aaggctggtc
     7021 ttcaaaacat tactcttatg atgatagaga aggaagattt gactcccttt atccatcttc
     7081 aacatcatca gcaggagctg acattaaaag atggcatcgt tattacagct aaactcgccc
     7141 agctggcagg tgtcaaggtt gggcagactt tagaaattga aggtaaggaa ctaaaggtcg
     7201 ctgctattac tgagaactac gttggtcact ttatttatat gagtcaggct agctatgagc
     7261 aactttacgg acagctaccc caagccaaca cttatctggt ctcattaagg gataccagtg
     7321 caactagtat cgaaagtcag gcgggcttgc ttatgaatca atctgcggtg tccagcgttg
     7381 tccaaaatgc ttcagccatt cgactcttcg actctatcgc tagctcactc aatcagacca
     7441 tgaccatctt ggtcatcgta tcggttctat tagctattgt catcctttac aatctgacca
     7501 atatcaacgt agctgagaga atccgtgaac tctccactat caaggttctc ggttttcata
     7561 ataatgaagt caccctctac atttatcgtg agacgattgt gctgtccctt gtgggaatcg
     7621 tacttggtct ggtagctggt ttctatttac accaattttt gattcaaatg atttcgcctg
     7681 cgactattct cttttatccg cagataggct gggaagtcta tgtaatccca gtggcagcag
     7741 taagcatcat tttgaccttg cttggtttct tcgtcaatta ttatctgaga aaggttgata
     7801 tgttagaagc cctgaaatct gtagagtaag gtagttattt ttagctgatt gaacttctat
     7861 ttactaatat tcaaaaatcc tccgtttcaa agagcaggga actctttgtg acagaggatt
     7921 ttttctatag ggctttagca gctgcaattg cggcttcgaa gtttggctca gaattgatat
     7981 tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc gaggacaaag actgcgcgtg
     8041 ctaataggtg ccattcgttg atcaagaggg cataatcgcg cccgaaagaa tggtcaaagt
     8101 agtctgaaag cataatggca ttgtcaaggc cttcagcacc gcaccaacgt ttttgagcaa
     8161 aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc cagtccagcc aattcttcat
     8221 taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat agaaggaacg acactcaaga
     8281 cttttttctt gccatcaaaa tcagccagag attttttaga aagatctgtt gtagtaagag
     8341 aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc tgtaaagctc acaggatttc
     8401 cgagaaaagt taccatagga tactccaatc ttttttcttc cattgtatct gaaacagtca
     8461 gaattttcca atgatttgac cggaaatgtg ggcatagaaa aaacgccagc tcacatgaga
     8521 atgacgtttt tcagaggctt attttgccaa tccttcagca atcttgtcaa ggttgtattt
     8581 catcatgctg tagtagctgt cgccttcttt accttgttct gcgatagagt cagtaaagat
     8641 ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt ttcattggac ggtcatccac
     8701 acttgattct acaaagagtg atggaacttt tgtttggcga agtttttcaa ccaaggtctt
     8761 gatttgttca ggagttcctt cttcttcagt attgatttcc cagatgtagg cacttgggac
     8821 accataggct ttagagaagt atttgaatgc tccttcgctg gttacaatga gtttcttttc
     8881 agcagggatc ttattaaatt tatccttact ttctttatca agtttgtcta acttatcagt
     8941 atattctttg agattttttt catagaattc tttattgtta gggtctttgg cgctcaattg
     9001 tttggcgata tttttagcaa aaataatacc gttttcaagg ttaagccaag cgtgtgggtc
     9061 ttcttttcct ttttcatttt gaccttcaag gtagataaca tcaacgccgt cgctgactgc
     9121 gaagtagtct ttgttttcag ttttcttggc attttctacc aattttgtaa accaagcatt
     9181 gccacctgtt tcaaggttga taccgttata gaaaatcaaa tcagcctcag aagttttctt
     9241 aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc ccaatcggaa cgatactatg
     9301 aaggtcaatt ttgtcaccag caatattttt agtaatatca gcgatgattg agtttgtagc
     9361 aacaactttt agtttttgac cagaagttgt atcttttttt ccgctagcac atgctacaag
     9421 aatgattgca gaaagaaaga gaacgagtaa tgtacctaat tttttcatta gatcctccaa
     9481 tttattaggg ctttgcccct tattttaaca aatgtttatt tttcagtttc aaatatcgtt
     9541 gtttgggagc gataaagaag ctaatgagaa agaaactagc agctgtaagc acgatactag
     9601 aacctgccgc aacattaaaa ctatagccaa taaagagtcc caaaactgaa gcagtagctc
     9661 cgaaggttga ggaaaggaaa atcatgcttt tcagactatt agcatacaga taagcagttg
     9721 cagctggggt aatcagcatg gctacaatca ggatagttcc gacactttgc atggctgtca
     9781 cagacacgag agtcaggagt accatgagaa ggtagtgata gaaattgaca ggcattccca
     9841 tggctttagc caagagttca tcaaaggaag ttatcaagag ttgcttgaag aaaatccaga
     9901 ttaacaagag gatggctgcc cccacaccca tagtaataaa catatccgta tcttggacgg
     9961 ccaggatatt accaaaaagg atatggaaaa ggtcagttga acttttagcg acaccaatca
    10021 agatgatacc gagggctaag aaagaagaaa aggtaatgcc gatggcggta tcgcttttga
    10081 taatcgagtt tcctttgatg taggtaatga tgatggcagc tagcaatcca aagacaatgg
    10141 ctccgataaa gaagtcaagg cccaagatga aggagagggc tacacctggt aagacagcat
    10201 gtgaaatggc atctcccatg agtgacatcc cgcgtagaat aatgaaacat cccacagctc
    10261 cagctacaat cccgacgaca atagctgtta tcaaggcatt ttgtaggaaa tggaattttt
    10321 gcaatccatc gataaattct gcaatcatag gtcacctcca ttgaaaaaga gttgattacc
    10381 gtaagcttct tttagattgg tttcggtaaa agtttctttt gttggaccaa aggcaatcac
    10441 ttctcgattg acaagtaaga cttgatcgaa gtagtgggga atcttgctga ggtcgtggtg
    10501 aacgatgaga accgtcttcc cagctttttt caaatctctc agcgtattca tgatgatttc
    10561 ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag aggatatagt cggcttcctg
    10621 caccaaacat ctggcaatca aaacccgctg gaattgacct ccagacagtt gactaatttg
    10681 acgttcagcg tagtcagcta ggccgacgat ttcaagggcc tcttgcactt tcttccaatg
    10741 tttagtcttt aaacttcgaa agagaggaat agagggaaat agtcctaacg agacgcattc
    10801 cttgaccttg atgggaaagt tgtagtcgat attgattttt tgttcgacat aggcaattcg
    10861 gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc tgaccttgat gtgggataat
    10921 tcccagcata ccttttaata gtgttgattt cccagcgccg tttggaccaa tgatgccggt
    10981 aattgttggt ccatggagca ctagtgaaat atccttaagt gccaacgttt ctttgtatga
    11041 gacactgagg ttttcgatac gtatcataaa cttgtattcc tcctgtctct taatatacat
    11101 taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta aaataataac tgaaaaatag
    11161 att
//
LOCUS       DAVKBC010000051        10776 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVKBC010000051 DAVKBC010000000
VERSION     DAVKBC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10776
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.051"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..170
                     /locus_tag="VWX64_001751"
     CDS             <1..170
                     /locus_tag="VWX64_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9191176.1"
                     /translation="TVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSGVTLIT
                     GKNGTGKSTLL"
     gene            complement(536..1846)
                     /locus_tag="VWX64_001752"
     CDS             complement(536..1846)
                     /locus_tag="VWX64_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU9191177.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2083..2955
                     /locus_tag="VWX64_001753"
     CDS             2083..2955
                     /locus_tag="VWX64_001753"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU9191178.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQRAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3086..3932
                     /locus_tag="VWX64_001754"
                     /pseudo
     CDS             3086..3932
                     /locus_tag="VWX64_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            4135..4968
                     /locus_tag="VWX64_001755"
                     /pseudo
     CDS             4135..4968
                     /locus_tag="VWX64_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857688.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            5145..6152
                     /gene="gap"
                     /locus_tag="VWX64_001756"
     CDS             5145..6152
                     /gene="gap"
                     /locus_tag="VWX64_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU9191179.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(6220..7056)
                     /locus_tag="VWX64_001757"
     CDS             complement(6220..7056)
                     /locus_tag="VWX64_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9191180.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            7182..9377
                     /locus_tag="VWX64_001758"
     CDS             7182..9377
                     /locus_tag="VWX64_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9191181.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            9430..9582
                     /gene="rpmG"
                     /locus_tag="VWX64_001759"
     CDS             9430..9582
                     /gene="rpmG"
                     /locus_tag="VWX64_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9191182.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            9592..9768
                     /gene="secE"
                     /locus_tag="VWX64_001760"
     CDS             9592..9768
                     /gene="secE"
                     /locus_tag="VWX64_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU9191183.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            9823..10359
                     /gene="nusG"
                     /locus_tag="VWX64_001761"
     CDS             9823..10359
                     /gene="nusG"
                     /locus_tag="VWX64_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU9191184.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            10481..>10776
                     /locus_tag="VWX64_001762"
     CDS             10481..>10776
                     /locus_tag="VWX64_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU9191185.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRKYDKEPYEEVGEISHRISEG"
BASE COUNT         3385 a         1839 c         2362 g         3190 t
ORIGIN      
        1 gaactgtttc ttttgctatt agttcaaaag gagaaaaaat gaaagtagaa aatatttcgt
       61 atagggtgga tcatcgtata ttgtttgata atatttcttt tgatacttcg agttcaggcg
      121 tgacattaat tactggtaaa aatggtacag gaaagtcaac tttactatag tagattgaaa
      181 ctagaatagt acacatctac ttctaaaata ttgttagaaa tcgatttgac tatcctgatc
      241 tatttgtcct gttcttattt catttcacta tatctcaaat tgagtatgac gaagtgcgct
      301 cccatgtcct gggaacgcac tttcttcata tttttcatat tcttgaatcc atcgataaag
      361 actattggga tgaattttta aagttgaact aatcattttt acaggatgag gtttacagca
      421 gagagtttga aggctttatc aaaggttttt cttggcataa tgacttttcc tcgtttccac
      481 ttaattttgt gtctacttta ttataccaag tccaccctta agttagataa taaatctaac
      541 ttaaggaagc tagaaggatg agaatccagg tggtcaagag tcccaaactt aagctgatgg
      601 ggacacccag aataatttgc tttttgaagg caaggccacg ttcctctata ttgggaagtg
      661 agagttgaat gagagaacca gctgatgaaa agggtgagat attagtagat agagcgccaa
      721 taacggtggc tgttgtgagt aagtgaatat caatctgggg attttgagca ctgatgatag
      781 caatgatggg aaagagggct ggagctacaa cggatagggt ggaactaaag agtgacatca
      841 ctccggctat cacacaaaag aacagaggta accagaaatg aggaatggat gttgtcatga
      901 ggtgccctat cagtgtgact aaacctgact tgaccgctag agacattagt aagctcatgc
      961 cgcagagcat gataattgta gcccagggaa ctttagccaa aatggcttct tgcttcccta
     1021 atttgagcct taaggcgagg cagaccatga gtattgagac aaagccaata tcaaatgttt
     1081 ttcgataagt agctatccag gcgatgtttg ggaaaatgag atgcaacaag ggaaaaagcc
     1141 aaaccaaaac catgctgctg atcatgagta aggtggtttg tctttgaacc ttgctgagga
     1201 gtggtggttg gtcaatagtc aaggatgagt ttgttcttcc cttgctatag tgactgtaac
     1261 aggataataa aagcaagacg atgagtgggt agataatgct gacgataaag atatgattgc
     1321 caagtgaaaa agcttgctct tcccatccca tttgcttaaa caggccttga aagacaatgc
     1381 ctgagctact ggttatcaaa ttagcccctc ctgaagctcc ccaattgacg gcttgagctc
     1441 caatcaaagg gtgtttgtcc gctttttgac agagggtaat cgctagagga cagcaaacgg
     1501 ccatagtagt gaaaaatcca gcacctaaag cagacaaaag ggttgccatc aggtataaaa
     1561 tcatgtagag ggcgttaggg taggtgcgtg tgcggtagag aatgtgttga gccaaaacat
     1621 caagagtacc gttagttatt gcaaagttat aaaagagaga gacgctaaaa atggtaaaaa
     1681 agagtgaggt tggccaaaaa tgaagaagtt ctttggggct taatcccatg agagtggttg
     1741 cgatgaggta agaaaaagca atagccagca ggccaatatt gattttggtg cggtaaccaa
     1801 ttccaatggc tagagcaatg gcgctaatca ttattaaatg aatcattgaa ttgtcctttc
     1861 agttagaata tggaaatagg ttggcaattt tggcgctcaa aagaccacct gtttcctatt
     1921 ggtacttgac tattatacac aaaaaaaata caattgtctt gacaattgta ttgacaattg
     1981 ttagaattaa aaatgaggta ttcaggcttg tgattttcta tggaagttaa tagtgattgc
     2041 ctctaatgct tacaagtgat attaaaaata gaggacctag tgatgtcaat catttcaact
     2101 gatttaaccc cttttcaaat agatgataca ttgaaagcag ccttgcgaga agatgttcat
     2161 tccgaagatt acagtaccaa tgccattttt gatcatcatg gccaagccaa ggtgtcgctt
     2221 tttgccaagg aagctggtgt tttagcgggg ctaaccgttt ttcaaagggt ttttacccta
     2281 tttgatgccg aggtgacctt ccagaatcct catcaattta aggatgggga tcgtttgact
     2341 agtggcgatt tggttttaga aatcataggc tcggtgagaa gtctcttaac atgtgaacgc
     2401 gttgccttga attttttaca acatttatca gggatcgctt cgatgacagc tgcttatgta
     2461 gaagccttag gcgatgattg cattaaggta tttgatactc gaaaaactac tcctaattta
     2521 cgtctttttg agaaatatgc cgtgagagtt ggcggtggct ataatcatcg ctttaattta
     2581 tcagatgcta tcctgctaaa agacaatcac attgcggcag taggtagtgt tcaaagggca
     2641 attgctcaag cgcgtgccta tgctcctttt gtgaaaatgg tcgaggtgga agtggaaagc
     2701 cttgctgctg ccgaagaagc tgcggcggcg ggtgctgata ttatcatgtt ggataatatg
     2761 tcattggaac agattgaaca ggccattacc ctaattgcag gacgttctcg gattgaatgt
     2821 tctggaaata ttgatatgac cactattagc cgttttcgtg gtttagcgat tgattacgtc
     2881 tccagtggta gtttaaccca tagtgctaag agtcttgatt tttccatgaa gggtttaacc
     2941 taccttgatg tctaagttgt aaaataaact aactttttaa aggatgtctt tcctctagaa
     3001 cgagttttat gtcagatagt ttaaacgcct cttcaaatat agtaaaatga accaaaaata
     3061 gtacacaatg tggtataatc ttcttatggc atattcaata gattttcgta aaaaagttct
     3121 ttcttattgt gagcgaacag gtagtataac agaagcatca cacgttttcc aaatctcacg
     3181 taataccatt tatggctggt taaagctaaa agagaaaaca ggagagctaa accaccaagt
     3241 aaaaggaaca aaaccaagaa aggttgatag agatagactt aaaaactatc ttactgacaa
     3301 tccagacgct tatttgactg aaatagcttc tgaatttggc tgtcatccaa ctaccatcca
     3361 ctatgcgctc aaagctatgg gctacactcg aaaaaaagaa ccacacctac tatgaacaag
     3421 acccagaaaa agtagcctta tttcttaaaa attttaatag tttaaagcac ctagcacctg
     3481 tttagattga tgaaacagga ttcgatactt atttttatcg agaatatggt cgctcattaa
     3541 aaggtcagtt aataagaggt aaagtatctg gaagaagata tcagaggatt tctttggttg
     3601 caggtctaac aaatggtgag ttaatcgctc caatgactta cgaagagacg atgacgagcg
     3661 acttttttga agcatggttt cagaagtttc tcttaccaac attaaccaca ccatcggtta
     3721 ttattatgga taatgcaaga ttccatagaa tgggtaagtt agaactttta tgcgaggagt
     3781 ttgggcataa acttttacct cttcctccct actcgcctga gtacaatctt attgagaaaa
     3841 catgggctca tatcaaaaag cacctcaaaa aggtattacc aagttgcaat accttttatg
     3901 aggctctttt gtcctgctct tgtttcaatt gactatagtt cacggataca gttgggaaag
     3961 aagctattaa atatttggag agtccttttg ggatgaacat gtcaaatatt actatagatg
     4021 ggcaagaaaa gatgggcaag aaatggattt gagtcaaacg atgcttctta tgctcaagta
     4081 gtgagtcttt atgatgatac aagtatctct gttagtaata atgagacgga caaagtgttg
     4141 gctggatccc tctatactga tacaaatgaa cagggattaa cgattccaag cagtttacta
     4201 aaaaattgga atgaacagac aggaaaaaat ttgacagcta atgatcttat tggcaaatca
     4261 gtctcagtca gcattgtaga aagtgctgcc gaaactagta agattgctca atttcaaacg
     4321 aagattgtac gtgtaatcaa tgatgaagat gacatggagg acagcaacag tttcatgctg
     4381 tctcatcaaa tggaaacgat tttgaaagag gctggattta cgaaagctgt atcttatttt
     4441 atcttggaac tcaaagatcc atcacagaca aaagtagtaa cagaagaatt acagaaaaat
     4501 aagaagtata ctgtgctttc ttaacagaga gttcttgata ttgtgattac ctttattcgt
     4561 gttattcagg gattattgat tgtgctttca tcacaagcta ttgtggtagc agcggttatg
     4621 attggtatca ttatttacat caatatcatg caacgttcca aggaaatagg tgtcatgaaa
     4681 gcagttggtt atcagaatcg tgatgtcaaa ggaattttta tttacgaggc tatctggatt
     4741 gtaggcatcg ccttgctgct ggcatttttg gttgcacaag gggtgggaag tttggcgaat
     4801 gcgattgtaa gtcactttta cccatccatc actaaggttt ttgaattaaa tcttttatct
     4861 gttttaggaa ctctagtttt cgctctatta cttggttatg tctcagccta cttcccggcg
     4921 cgtaagatta gtaaaatgga tcctgtagaa tcgttacgct atgaatagta agggattcct
     4981 tgatttacag tcttaaaaag aaactaacat agaaaaacaa tggccatact tgcaattcaa
     5041 ctcaaatagt tgtataatag gtttgttgaa aggtgatttg tagtgattca agttactctt
     5101 ttcacaataa aaatttcatg attttcataa ggaggaaatc actaatggta gttaaagttg
     5161 gtattaacgg tttcggacgt atcggtcgtc ttgctttccg tcgtatccaa aacgtagaag
     5221 gtgttgaagt tacacgcatc aacgacctta cagatccagt tatgcttgca cacttgttga
     5281 aatacgacac aactcaaggt cgtttcgacg gtactgttga agttaaagaa ggtggatttg
     5341 aagttaacgg taaattcatc aaagtttctg ctgaacgtga tccagaacaa atcgactggg
     5401 ctactgacgg tgtagaaatc gttcttgaag ctactggttt ctttgctaag aaagaagcag
     5461 ctgaaaaaca ccttaaaggt ggagctaaaa aagttgttat cactgctcct ggtggaaacg
     5521 acgttaaaac agttgtattc aacactaacc acgacgttct tgacggtact gaaacagtta
     5581 tctcaggtgc ttcatgtact acaaactgct tggctccaat ggctaaagct cttcaagaca
     5641 actttggtgt tgttgaagga ttgatgacta ctatccacgc ttacactggt gaccaaatga
     5701 tccttgacgg accacaccgt ggtggtgacc ttcgccgtgc tcgcgctggt gctgcaaaca
     5761 tcgttcctaa ctcaactggt gctgcaaaag ctatcggtct tgtaatccca gaattgaatg
     5821 gtaaacttga tggatctgca caacgcgttc caactccaac tggatcagtt actgaattgg
     5881 tagcagttct tgaaaagaac gttactgttg atgaagtgaa cgcagctatg aaagcagctt
     5941 caaacgaatc atacggttac acagaagatc caatcgtatc ttcagatatc gtaggtatgt
     6001 cttacggttc attgtttgac gcaactcaaa ctaaagttct tgacgttgac ggtaaacaat
     6061 tggttaaagt tgtatcatgg tacgacaacg aaatgtcata cactgcacaa cttgttcgta
     6121 ctcttgaata cttcgcaaag attgctaaat aattcttgag ttgatagaaa gcaaggcttt
     6181 gtggtcttgc ttttttatat ggaaaaatgg atgacacgat catccattct tttttaattc
     6241 tttttcaaat gtatttgaaa gggtagtgaa agttagcttc tctaaagtaa gtgggtgggt
     6301 aaaggaaagt cggaaggcat gaagcataag ccgacttgtc tttgatttac tattatagag
     6361 agggtcgccc aggataggaa gattatgatg cgaaaggtgc acacgaatct gatgggttcg
     6421 ccctgtcttt agcttgcaac gagccaagga agtcttgttt gagaattgct ttaatctgct
     6481 tacatgcgtt tcagcatatt gcccattttt tgcatcaact attctttttc tacgatcatg
     6541 gcgatcacgt ccaattttgt ctctgaaaac aagttctttt ctgttgatat ttccatcaac
     6601 tagagcccaa tattctctag aaatctcttt tttctccaat aagcgattga gaatgggcag
     6661 gataaaagga tttttggcaa agagaactaa gccactggtt tccatgtcca gacgatgaac
     6721 gacatagcag gtttggccaa cataggtact gacatggtta agaagggcaa tttcgtttgg
     6781 ttgattacca tgcgttttca tcccctctgg tttgtttaca ataatcaagt gttgatcttg
     6841 ataaacttcc tgcactaagt ctgggttgcc ccaagggatc gtcttttggg gataatcttc
     6901 ctcgtcaaaa gtcaactggc aaacatctcc aggatttacg atttccttcc agtggacttc
     6961 ttcttgattt atcaaaatat gtttcttgat tctcaaaaaa tgacggattt ttctagggat
     7021 gaggagttgt tcctcaagta attgctttac cgtcatttga ggtagagagg cgggtaatgt
     7081 aaatgtgaat tgcatacaga tattgtaaca aaaaaagccc tatttggata ggaaatagct
     7141 aaattcttgt cttcctatga tgaagatgat aaaataaacg catgaaatta gataaattat
     7201 ttgagaaatt tctttctctt tttaaaaaag aaacaagtga actagaggac tctgattcta
     7261 ctatcttacg tcgctctcgt agtgatcgaa aaaaattagc ccaagtaggt ccgattcgaa
     7321 aattctggcg tcgttatcat ctaacaaaga ttatccttat actaggtttg agtgcaggct
     7381 tgctagttgg aatctatttg tttgctgtag ccaagtcgac caatgtcaat gatttgcaaa
     7441 atgccttgaa aactcggact cttatttttg atcgtgaaga aaaagaggct ggtgccttgt
     7501 ctggtcaaaa gggaacctat gttgagctga ctgatatcag taaaaacttg cagaatgctg
     7561 ttattgcgac agaagaccgt tctttctata aaaatgacgg gattaactat ggccgtttct
     7621 tcttggctat tgtcactgct ggacgttcag gtggtggctc taccattacc caacagctgg
     7681 ctaaaaacgc ctatttatca caagatcaaa ctgttgagag aaaagcgaaa gaatttttcc
     7741 ttgccttaga attaagcaaa aaatatagta aggagcaaat tctaaccatg taccttaaca
     7801 acgcttattt tggaaatggt gtgtggggtg tagaagatgc gagtaagaaa tactttggag
     7861 tttctgcatc agaagtgagt ctggatcaag ctgcgactct ggcagggatg ctcaaggggc
     7921 cggaactgta taatcccttg aattccgtag aagattctac taatcggcgc gatactgtct
     7981 tgcagaatat ggttgcagca ggatatattg ataaaaacca agaaaccgaa gctgctgaag
     8041 ttgatatgac ttcgcaattg cacgataagt atgaaggaaa aatctcagat taccgttacc
     8101 cctcttattt tgatgcggtg gttaatgaag ctgtttccaa gtataatcta acagaggaag
     8161 agattgtcaa taatggctac cgcatttaca cagagctgga ccaaaactac caagcaaata
     8221 tgcagattgt ttatgaaaac acatcgctat ttccgagggc agaggatgga acgtttgctc
     8281 aatcaggaag tgtagctctc gaaccgaaaa cagggggagt tcgtggagtt gtcggtcaag
     8341 ttgctgacaa tgataaaact ggattccgga atttcaacta tgcaacccaa tcaaagcgta
     8401 gtcctggttc tacaattaag cctttagttg tttatacgcc agcagttgaa gcaggctggg
     8461 ctttgaataa gcagttggat aaccatacca tgcagtatga cagctataag gttgataact
     8521 atgcagggat caaaacgagt cgagaagttc ctatgtatca agccttggca gaatcgctta
     8581 atctacctgc tgttgccact gttaatgatt tgggtgtcga caaggctttt gaggcaggcg
     8641 aaaaattcgg actcaacatg gaaaaggtcg accgtgttct tggtgtcgcc ttgggaagcg
     8701 gtgttgaaac caaccctctt caaatggctc aagcatacgc tgcctttgca aatgaaggtt
     8761 taatgcctga agctcatttt attagtagaa ttgaaaatgc tagtggacaa gttattgcga
     8821 gtcataaaaa ttcacaaaaa cgggtgattg ataagtctgt agctgacaag atgaccagta
     8881 tgatgttggg gactttcacc aacggtaccg gtattagttc atcgcctgca gactatatta
     8941 tggcagggaa aactggaaca actgaagcag tttttaatcc ggagtacaca agtgaccagt
     9001 gggtaattgg ttatactccg gatgtagtga ttagccactg gcttggcttt ccgaccactg
     9061 atgaaaatca ctatctagct ggctctactt caaacggtgc agctcatgtc tttagaaaca
     9121 ttgccaatac cattttaccc tatacgccag gaagtacctt tacggttgaa aatgcttata
     9181 agcaaaatgg aattgcacca gccaatacaa aaagacaagt acaaaccaat gataatagcc
     9241 agacagatga taatttgtct gatattcgag ggcgtgcgca aagtctagta gatgaggcta
     9301 gccgggctat ctcagatgcg aagattaagg aaaaggctca aacaatatgg gattcgatag
     9361 tcaatctatt tcgctaagat gcttgtcaaa gcctagcttt cttgttataa tggataagat
     9421 ggaggcgtta tggcactaaa aaaagcaagc ctagcttgtg cggtttgtgg ttcgagaaac
     9481 tattcaatca agatcagcgg aaaccccaag cctacacgac tagaagtaaa taaattttgt
     9541 aagcattgtg gcaagtacac tacacataga gaaacgagat aggagagagc gatgcgtttt
     9601 attggagata tttttagact tcttaaagac acaacgtggc caactcgcaa ggaaagctgg
     9661 agagattttc gttctatcat ggaatacaca gctttctttg tagtaattat ttacattttt
     9721 gaccagttga ttgtttcagg tttgattcga tttattaaca ttttttagaa gattagtgga
     9781 gttaattaca ctagaaatct tctatttatg aaaggaaata tcatggatag ttttgataaa
     9841 ggatggtttg ttttacaaac ttattctggt tatgaaaata aggtgaaaga aaatctatta
     9901 caacgtgcac aaacctacaa tatgttggat aatattctac gcgttgaaat tccaacacaa
     9961 acagtgcaag ttgaaaaaaa tggaaagaga aaagaagtag aagaaaatcg ctttccaggt
    10021 tatgttcttg tagaaatggt catgacagat gaagcttggt ttgttgttcg aaacacacca
    10081 aatgttacag gatttgtcgg atcacacggg aacagatcaa aaccaactcc attattggaa
    10141 caagaaattc gtgacatttt ggtatctatg ggacaaactg ttcaagaatt tgatttcgat
    10201 gttgagattg gtcaaactgt acgtattatt gatggtgctt ttgcagacta cactggtaag
    10261 attacagaaa ttgataataa caaagtgaaa atgattatct ctatgtttgg taatgacaca
    10321 gttgcagaag taaacctaaa ccaaatcgca gaattataac cctgagagag gctggagtct
    10381 ctcttttttg tgcagtttag gagctaaagg gaacagaatg gagaaaatgg aacaaatgtg
    10441 ttttctaatc tgttagactg tatctagaaa ggggaaaatt atgattaaag aattgtatga
    10501 agaagtccaa gggactgttt ataagtgtag aaatgaatat taccttcatt tatgggaatt
    10561 gtcggattgg gaccaagaag gcatgctctg cttacatgaa ttgattagta gagaagaagg
    10621 actggtagac gatattccac gtttaaggaa atatttcaaa accaagtttc gaaatcgaat
    10681 tttagactat atccgtaagc aggaaagtca gaagcgtaaa tacgataaag aaccctatga
    10741 agaagtgggt gagatcagtc atcgtataag tgaggg
//
LOCUS       DAVKBC010000052        10636 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVKBC010000052 DAVKBC010000000
VERSION     DAVKBC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.052"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(7..1431)
                     /locus_tag="VWX64_001763"
     CDS             complement(7..1431)
                     /locus_tag="VWX64_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9191186.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTATILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(1976..4255)
                     /gene="pulA"
                     /locus_tag="VWX64_001764"
     CDS             complement(1976..4255)
                     /gene="pulA"
                     /locus_tag="VWX64_001764"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU9191187.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLTPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGTYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTVAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4367..6325)
                     /gene="ligA"
                     /locus_tag="VWX64_001765"
     CDS             complement(4367..6325)
                     /gene="ligA"
                     /locus_tag="VWX64_001765"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU9191188.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDKIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6418..7596)
                     /locus_tag="VWX64_001766"
     CDS             complement(6418..7596)
                     /locus_tag="VWX64_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9191189.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSIIVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FFLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7676..8539)
                     /locus_tag="VWX64_001767"
     CDS             complement(7676..8539)
                     /locus_tag="VWX64_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU9191190.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQETMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8542..10443)
                     /locus_tag="VWX64_001768"
     CDS             complement(8542..10443)
                     /locus_tag="VWX64_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9191191.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAKIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3186 a         2345 c         1902 g         3203 t
ORIGIN      
        1 tacacgttat ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata
       61 tttaattcct tgcactccag ctccagaacc tttgacacca aggaatggga aattatctgg
      121 accacgctgg gttttattat taatgtggac tgtacctact tcaagctttt cagcaatttc
      181 aaaggctttt ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt
      241 ggcaaaggca atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa
      301 tggctcttcc catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag
      361 gagattgccc tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc
      421 aatcaagccc caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt
      481 gtcaaatgga tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt
      541 atctgctaca ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta
      601 gctaaaggct cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac
      661 aagagctgca tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc
      721 aatacgttct ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc
      781 aatgatataa tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg
      841 aatccctgct tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg
      901 tggcttcaac atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa
      961 attaactgga taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac
     1021 aacagccagt ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt
     1081 gatacggaga ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc
     1141 aattgctgct ttaatccctt ttgctacttc tttggcaagg atagtaccaa ttttttcctt
     1201 atcgcgttct aaaatagttg ctgttttatg caaataagcc gcacgttcaa ttgctgataa
     1261 agctcgccat gctggtaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg
     1321 agtcatggct ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc
     1381 ttgttcagat gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc
     1441 ctcctgaaaa tgattaagat atattttacc aaattttcag aaaatcacaa ccctttttgc
     1501 aaaatttttg agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa
     1561 aaaaatccac tacatcaagg cgagactaat gtggtttgaa gaaattttcg aagagcgtga
     1621 atgagtatca tctatagtaa aataaaaaaa ctgaacaatt tggttgggga cagtcaaacc
     1681 aatttctcac aatgttttag aaacaagggt gtgctattcc aatttcaggc tactataact
     1741 gtcatagatt gctgaaacaa agtctaggta aaagtcttca taataaaaag accccctatc
     1801 aagtgttcaa aaactttgat aggaggtctt gttttgtgaa aatatttatc aaattttcta
     1861 tacaagtgag ctgttagcca ggttctttct attctttcaa tttcaatgaa tggatttttt
     1921 accaatactc ataactggga atttgtctgt ctaaaaatag cgagatagat ggtatttata
     1981 aaacactcaa gacagctaga ctaatatcat ttaaaacatt atcttctttt gagcgactgt
     2041 tggttaccaa catagctaaa tttcctgcat tttcaaattg atagggttct gatttagcat
     2101 tcacaactac caagaggtgt tctttgccgt gaacttcata gataaggcag ccgctatgtt
     2161 caatcgcaga atgcacaaag acatgatggt aaatttcatc atagctagag taagaaaaag
     2221 caacagtttt tgtcttcaat cggatgactt gacggataaa ctcaatactg tcttgacgct
     2281 cattaatcaa gttccagttc acttggttca cactgtcagg agcattatag ctattcatcg
     2341 cacgctctct atcatcatgg gtcaactcac cattttcacc agtcgcaacc agtttggtac
     2401 gaccaaattc ttgaccgatt tccataaagg ccatcccctg catgagcaga ttcatggctg
     2461 tggcagtttc gaccttgcgc atgatttgct ctgaactttg gtctggatga agggttgcca
     2521 ataaatcgtg aagattgtaa ttgtcatggg cttctacata gttaagcacc tgatttggat
     2581 gtgtataggt tcctaattca cgacttccta ggattgcttt agctagaatt ggctctgtcg
     2641 cagcaccact gacaaaacct gacttgatag caccataaac ttctccccct ttgacagcat
     2701 cgcgctgatt gtcattaaag aaaccaatat ttggcatctg gtaggcattg tccttcttgg
     2761 ccttatcata aggggtaaga cctgttccca tatcccatcc ttctccatag aggataatgt
     2821 tggagtcgat ttcatccaag ctttgacgaa tcatctgcat ggtcttgaca tcatgaatcc
     2881 ccatcaagtc aaaacggaag ccgtcaatat tatattcctg cacccagtat agaagagaat
     2941 caatcatata cttgcgaaac atttcgtgtt cactggctgt ttcatttcca acacccgttc
     3001 cattctggaa ggtaccatct ggattcatac gataatagta atcagggact gttgtttgga
     3061 atggtgcatc aacaactgag aaggtatggt tatagactac atccataatg actccaatac
     3121 ccgcatcgtg ataagcttga accatcacct tcaaatcacg aatgacctga gctggatcat
     3181 ctggattagt tgaaaaacta gtttctggcg cgttatagtt ttgtggatca taaccccagt
     3241 tgtaggttac atttccatcc tcatcgtatt ctttatgacg gtctgcaatt ggttgcaatt
     3301 gaacataatt gtagcccagc ttcttgatgt aatcaaaagc agttgactgg ccgtattggt
     3361 taactgttcc agcctgagca gcacccaaga aagttcctcg aagatgttca tctacacccg
     3421 atgtaggtga tttagtcaaa tcacgaatgt gcatttcaca gataactgcc ttacatggat
     3481 tttccaagcg ccaagtagcc tccgaaccgt gcttaacctc gaagttttca acttgctttt
     3541 ctacatggct cagaatagct gaacgtttgc catcagggct ggtcgcgatt gtataaggat
     3601 cacgtgtcag tgtttggtga tgagggaatt ggacttgata ctgataagtc ttacctacca
     3661 aatcttcttc aacatccaaa ctccagacac cgattgtatt gtccttatga ttataagagt
     3721 agctattgcc tcttttcatc tcaaaagtct tccaaacggg tgcatcatta gcagctgatt
     3781 cataaacgac aacttgcact tctgtcgctg taggtgacca gagggaaaaa tgagcctgat
     3841 tgtcctctac acggcaaccc aattctcctt ggtaacccca atgatgatca aaactagcac
     3901 tgttaatggc cttatcaaag gcaaaaggat tttgattttt atagaaagga ctggcaatag
     3961 caggattttc agagtaataa atcctatcat cgccttccaa aatccagacc tctgttaata
     4021 ggggatagtg attaaaacgg atagaatatt ctttactagt ttgacctgta tgaaccacaa
     4081 aattcaagct ttctataaca tgtgaacttg ggtgttcaaa gctaaataaa gctccaaaat
     4141 aatcttcttt gtaggttagc aaatcaattc gttgatcctg actttttaca aaggagcaag
     4201 tgtcatattc tccattctta cgatggtaat gaatgcgcat agggtagtta tacatttttt
     4261 atttttcctt tttactttgt ttctatttca ctaataaatt tttgtcaatc tcgtctcaat
     4321 taacagacat agtcatattc tctaaactct gtttttaaac gatccattac aaactttcta
     4381 gccatgcctc atctctgacc tggataccaa gttcttgtgc tttttgcagt ttacttccag
     4441 cgtctgcacc taccacgacg aggtcggtct ttttagaaac actacctgtc actttggcac
     4501 ccagactttc gagtttactt ttagcttctg agcgcttgag tcgttccaat tttcctgtca
     4561 ataccacggt caaacctgac aaggccgcat ccgctactac cgtctgtcct ttatagtcca
     4621 gattgacccc agtttctttc aattctctga gcagaatttc agagccttct gtcgcaaaat
     4681 aagtctgaag acttttggca atcacgccac ctagactttc aatactagcc acttcctctg
     4741 aatctgcctg atacagattt tcaattgaat ggaaatattg aagtaaaagc tgactagcct
     4801 tgcttccgac atgacgaatt cccaaaccaa ataagagctt ctcggcagaa ttttcctttg
     4861 atgcttggat agcctgatac agtttagcag cggacttttc cttaaccccc tctaaaagga
     4921 ggaaatcctc ttcttgcaaa cgataaatat ccgccacatc cttgactaaa ttagcagcaa
     4981 aaagcttctc aacaatagat ggaccaaggc ctgtaatatt catagcatca cgagaagcaa
     5041 agtgaatcaa gccttccatg atttgagcag ggcaacgcgg attgatacaa cgtagggcca
     5101 cttcatcttc aaagtgcaac aagtcagagt tacaacttgg acagtttgta gggatatcta
     5161 gtttttcttc agaaacccgt ttggactcta ccacacgtaa aacggcaggg atgatgtcac
     5221 cagccttata tacaatgacc gtatcgtctt ttcggatatc tttttcagca atataatcta
     5281 cattgtgcag ggtcgcacgg ctaacagtcg taccggcaag ttgtactggt gttagattag
     5341 cagttggagt tacaacaccg gtacggccaa ctgtccagtc aactgataag agttgagctt
     5401 ctttttcttc agcagggaac ttgtaggcta ctgcccactt tggagcctta acggtaaaac
     5461 caagttcttc ttgacttgct aggtcgttga ccttgattac cactccatca atatcgtaag
     5521 gcagattttc ccgttcctgt cctacttctt ggataaaatt ccagatttta tctatgtttt
     5581 cagccaagat tcgcttagga ttgaccacaa aacctagttg ttctaggtac ttcaaaccct
     5641 tttcttggct atcacgagtt gaagggctgg cttcttgata gagaaacgtt gcaagattac
     5701 gcttggcaac tactgctgta tccaactgac gcagagttcc tgctgccgca ttacgaggat
     5761 tagcaaattc aggctctcca ttttcttggc gcacttggtt aacttggtca aaggaagcgc
     5821 gtggcatgta acattcccca cgaactgtga tatctagttc ttctggcaaa gtcaaaggga
     5881 tgtccttaac acgcttgagg ttttctgtga tattttcacc aattgaacca tctccacgtg
     5941 ttaccccagc aaccaaaatc cccttttcat aagtcagcga gatagataag ccatcgattt
     6001 tcagctcaca aatataggtc ggatgagcaa cttccttacg aacacgcgca tcaaaagcat
     6061 ctagctcctc acgtgaaaaa gcatcctgca aactataaag aggatactga tgactgtatt
     6121 tttcaaaacc atctaaaacc ttgccaccaa cacgatgagt cggactatct gctagcactt
     6181 gctctggata agcagtttct aactcgacca actcacggta aaggcggtca tactcactgt
     6241 ctgaaaccga gggattatcg ctggtatagt actcagtcgc atagcgattg agcaaagcga
     6301 ctaactcatt cattctttta ttcataagac cattttacca taaaacaaac cctcctcaca
     6361 aacgagaagg gcggaaaaaa cacttagttt gaaattattt ttgaaactca agcaacctta
     6421 tatcaatttt tcaaaatgag ttcgaacata aataaacgat atacaagaca agatgataac
     6481 accacttcca attatcagga aagaagagag atgtacactt ggcaagactg tcataaatcc
     6541 ttttgcaata ggcataaata gaatagctaa ggtaaaaatt gtactcagta ctcttccaag
     6601 aaattcgctc tcaaccttgg tttgtacttg agtaaaaaag tgaatattaa aaatcgtcat
     6661 aaacaattca caaactaaat ttccagaaaa ggaaagaaaa gttggaagtg gtaatcccat
     6721 cataaaaact ccgacacctg tcaaagccag taaaatcaaa agattataaa tattagcttt
     6781 aattttacta gctagaagag ccccaatgat ggaaccaata gcccccatag ttaaaatact
     6841 tgcataggct ccttctgacc cgtaaagctg attcgaaaag ggaagtagaa attcaaaagc
     6901 tgcaaaaaag aaattaacgc tggaagctac cagcaaaaag aagaaaattt cttgctgatg
     6961 ccagatatag tgtaacccat ccttgatatc tacaaaaata tctctcccag taaaagcctt
     7021 tttctcttga acttttgctt cctcttttgg aaggaaagcc actagaacaa aagcaatgaa
     7081 aaaagtcagc gagtctagca gtagcgtcat atggagactt gcaaactgta aaacaaggaa
     7141 ggaaagaaca ggagagctaa cacctacaac ctgcaaaacc agctctaagc gagaattata
     7201 gatcacaatc tcatctttct ccaccacttc agttatgata gctttattgg ctgtgcgaga
     7261 aaaggcaaaa gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa tcatccagct
     7321 atcattcctt atgaaagaaa tagccagaca aagaatccca caaacaagat ctgccgtcat
     7381 taaaatctta cgacgagaaa aacggtctga aataactccg ccaaagggat tgacgataat
     7441 agatgtgacg agctcagaaa tctgatacat tcctaaaact gtctgtccta tagtccccat
     7501 agaagccaac cagacactat ttccataatc atagagcata tttcccattt tattgatagc
     7561 cccacggcta atcaactgca ctgcatagcg attcatatta aagctcctct caaattttga
     7621 aactattgta tcaaaaccga aaggagcttt ttattttttc ccttatttgg gaaaattaac
     7681 ttttgacaaa tttttcgtag tgttcctgat aataggctac ttgctctgga agacctaaca
     7741 catcaaaaat atgcatggtc tcttgcatct gcttacagcc ttctttacac tgtccttttt
     7801 gatataaggc aaaacctttt aaataatgga aaacattacg ctcataaagc ttaatacctt
     7861 tgtcaataat cttctctgta taagcctcaa aatagttggc attataaaaa gaagaatgct
     7921 ctaaacaatg ctggtaacaa ttgagggcca aaatcaacac taatctctta tggcgactaa
     7981 tctcttggta aaattcctcc ctctccataa cttctctacc aatccgagtg acatagtcta
     8041 catcgtagaa actatagagg ttaccgaaaa gaatcaactc atacatggtc cattcttctg
     8101 ttttgaagag ataatctgct accttatcca aatcatcctg cttcatatca taactcgcat
     8161 ctctttgaca aatcagacct tgtagcaaaa tccagttcag ctcaaaataa aggggagtcg
     8221 tcgaactctt agacttttca agttgttctc tttgaagctt ttgaaaacct gcaatatcgt
     8281 ttgaatagta aagtgggata atctgtgcca tcatagacac atgttcatga ttatgaaaat
     8341 tccttgcctt atccatgaaa ttttcgattg ttacatgaat gttatccaaa atctcaaaga
     8401 aacgggagac tgccaggtca gactccccaa gctcaaagcg agataactga gaggtagagc
     8461 aggattcgcc tgctgcttcc tttaaagaat aatttccact tgttcgaaat tcacgaaata
     8521 cttttccaag atgttccatc tttacacctg atctgataat tcttcccact caagcatagc
     8581 ttcttcctga cgatggctga ttttgtccag ctcagcctgt aattccatga gtttgtcggc
     8641 atcgtttgtt tccaacattt gttcagaaat ggcttggctt tgactttcta gctcttcaat
     8701 tttagcttct agactttcga tttgtcgcat gagtttgcga acttcttttt gactttcttt
     8761 ctgggcctga tagtcattga ctggacttgc ttcctttgct tgattgctag ttgaagcttc
     8821 ctcagtctga ctcatttctg ctgttgcttt cttctcaaca tagtagtcgt aatctccaag
     8881 gtagagagtt gaaccattct cagacaattc caaaacatga gttgccacac gattgataaa
     8941 gtaacgatca tgactgacaa aaagcaaggt accatcaaag tcaatcaaag cattttccaa
     9001 cacttccttg ctatcaatat ccaagtggtt ggtcggctcg tcaaggatca ggaagttgtt
     9061 gttttccata gacaatttag ctaaaagcaa acgagctttt tcgccaccag atagcatgcc
     9121 gactgatttt ttaacatcat ctcctgagaa aaggaaggct ccaagacggt tgcggatttc
     9181 aacttctggt gtcagtttga aatcattcca gagttcatcc agcaccgtat tacttggtgt
     9241 cagcttgctt tgggtttggt catagtaacc aacctcaaca ttagcgccaa agcgcttttc
     9301 acctttgata aaaggaatct ggtccacaat agacttgata aaggttgact tgccgatacc
     9361 atttggacca acgatagcga cagcattcat cttacgaaga tctaggttga taggttgtga
     9421 caagacttcc ccgtcataac caatagcagt attttcaaca gtcaaaacaa cattgcccga
     9481 cgttttttca gactggaagg tcatgttggc tgctttcttg ccagcttcag gcttgtccaa
     9541 acgctccatt ttttctagtt gtttacggcg agattgagca cgtttagtcg ttgaagcacg
     9601 aactagattg cgattgacaa agtcttccag agcagcgatt tccttctgtt gcttttcata
     9661 gttttttgcc tcagtagcta gcttttgctc cttcaattcg acaaaacgag agtaattccc
     9721 cacatagcga tccaaggaat gcttggtcaa atctagcgta attgtcgcaa ccttgtccaa
     9781 gaaataacgg tcgtggctga cgataatgag ggcaccgcta tagtttacca agtaattctc
     9841 tagccaggcg atggtttcaa tatccaagtg gttagttggc tcgtccaaga ccaagagatt
     9901 gggcttttca aggagcattt tggcaagtgc caaacgagta ttttgaccac cagaaagctc
     9961 agcaattttc atctgccaca tagactcgtc aaacttgaat ccattcaaaa tcgctcgaat
    10021 atcagcttca taggtaaagc cacctgcttg gcgaaaattc tcagataagc ggtcataatc
    10081 tgacatcagt ttatccaaat cctcaccaga cttttcaccc atctccagct ccatctgacg
    10141 cagttgtctc tccgtccgac gcaaatcatt aaagacatga agcatttcat cgtagatggt
    10201 attttcagac tcaaaacggc tatcttgggc taggtaagac agagaaatat cttttttctt
    10261 attgatttct ccgctagttg gctcctcttc tccaactaaa atcttcaaaa gagtagactt
    10321 acctgcacca tttttcccaa caagagcaat ccgatctcgt tcatcaacct gcaggttgat
    10381 attatcgaaa agaacctctc ctgcaaaaga acgttcaatt ttattagctt gtaaaataat
    10441 catacaagta gtatagcatg tttccctaag tcattcaaga taatcgtaag tcttttagta
    10501 caacttttat aacataaaat aaactaaatt atgtatattt tatattagat tccttcacta
    10561 tcttgttgga ttttctaacc agctaatctt gtttcaaata gttatcgcac aagtctatta
    10621 tttaattctt ttcatt
//
LOCUS       DAVKBC010000053        10630 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVKBC010000053 DAVKBC010000000
VERSION     DAVKBC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.053"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..306
                     /locus_tag="VWX64_001769"
                     /pseudo
     CDS             1..306
                     /locus_tag="VWX64_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            404..616
                     /locus_tag="VWX64_001770"
                     /pseudo
     CDS             404..616
                     /locus_tag="VWX64_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            516..962
                     /locus_tag="VWX64_001771"
     CDS             516..962
                     /locus_tag="VWX64_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9191192.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1100..2404)
                     /gene="eno"
                     /locus_tag="VWX64_001772"
     CDS             complement(1100..2404)
                     /gene="eno"
                     /locus_tag="VWX64_001772"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU9191193.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2568..3014
                     /locus_tag="VWX64_001773"
     CDS             2568..3014
                     /locus_tag="VWX64_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU9191194.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3011..4126)
                     /locus_tag="VWX64_001774"
     CDS             complement(3011..4126)
                     /locus_tag="VWX64_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU9191195.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFNKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4135..4464)
                     /locus_tag="VWX64_001775"
     CDS             complement(4135..4464)
                     /locus_tag="VWX64_001775"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU9191196.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4409..4780)
                     /locus_tag="VWX64_001776"
     CDS             complement(4409..4780)
                     /locus_tag="VWX64_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU9191197.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4839..6272)
                     /gene="glgA"
                     /locus_tag="VWX64_001777"
     CDS             complement(4839..6272)
                     /gene="glgA"
                     /locus_tag="VWX64_001777"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU9191198.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6269..7408)
                     /gene="glgD"
                     /locus_tag="VWX64_001778"
     CDS             complement(6269..7408)
                     /gene="glgD"
                     /locus_tag="VWX64_001778"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU9191199.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7398..8540)
                     /locus_tag="VWX64_001779"
     CDS             complement(7398..8540)
                     /locus_tag="VWX64_001779"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU9191200.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8560..10458)
                     /gene="glgB"
                     /locus_tag="VWX64_001780"
     CDS             complement(8560..10458)
                     /gene="glgB"
                     /locus_tag="VWX64_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU9191201.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTN"
BASE COUNT         3244 a         2336 c         1874 g         3176 t
ORIGIN      
        1 aatccagacg cttatttgac tgaaatagct tctgaatttg gctgtcatcc aactaccatc
       61 cactatgcac tcaaagctat gggctacact cgaaaaaaag aaccacacct actatgaaca
      121 agacccagaa aaagtagcct tatttcttaa gaattttaat agtttaaagc acctagcaca
      181 ggtctaacaa atggtgaatt aatcgctcca atgacttacg aagagatgat gacgagcgac
      241 ttttttgaag tatggtttca gaagtttctc ttaccaacat taaccacacc atcggttatt
      301 atagtgaaat gaaataagaa caggacaaat cgatcaggac agtaaaatcg aattctaaca
      361 atgttttaga agtagaggtg tactattcta gtttcaatct actatattaa tggacaatgc
      421 aagattccat agaatgggga agctagaact cttgtgtgaa gagtttgggc ataaactttt
      481 acctcttcct ccctactcgc ctgagtacaa tcttattgag aaaacatggg ctcatatcaa
      541 aaagcacctc aaaagggtat taccaagttg caataccttt tatgaggctc ttttgtcttg
      601 ttcttgtttc aattgactat ataaattgtc taagcgaaac aaccgataag aattggcaca
      661 aaagcgaccg tatttttgtt accaatacag gaaaaccagt tcatagttct atcttgagca
      721 agtctctcca gcgagcaaac gaacgcctta aaaaaccaat tcccaaacat ctgtcccctc
      781 acatcttcag acacaccact attagcatct tatcagaaaa taaaattcct ttaaaaacaa
      841 tcacggacag ggttggtcat tccgactctg aagtcactac ttccatctac actcacgtca
      901 caaagaacat gaaagatgaa gcaatcaatg tactggataa agttatgaaa aagatttttt
      961 aaaaagtttt gtcccttttt tgtcctctaa atacaaaaat agcccttcgg ataaaatccg
     1021 aggggctaga aacgttgtta aatcaacggc cgaacttttg aatttcatgg ttcgggataa
     1081 aatagttcac tgaactattt tattttttaa ggttgtagaa tgatttcaat ccacgatatt
     1141 cagctacttc accaagttgg tcttcgatac gaagcaattg gttgtattta gcgatacggt
     1201 ctgtacgtga aagtgaacca gtcttgattt gtcctgcgtt agttgcaact gcgatatcag
     1261 cgattgttga atcttcagtt tcacctgaac ggtgtgatac aacagcagtg taaccagctt
     1321 ctttagccat ttcgatagct tcaaaagttt cagtaagagt accgatttgg ttaactttga
     1381 taaggattga gttagcagca ccttcttgga taccacgtgc aaggtagtca gtgtttgtta
     1441 cgaagaagtc gtcaccaaca agttgtactt tcttaccaag acgttcagta agagctttcc
     1501 aaccatccca gtcgttttca tccataccat cttcaatagt gatgattggg tatttgttaa
     1561 ccaattcttc aaggtagtcg atttgttctg cagatgtacg aacagcagca ccttcacctt
     1621 caaatttagt gtagtcgtaa actttacgtt ctttatcgta gaattctgat gaagcacagt
     1681 caaatccgat aaatacgtct ttacctggta catatccagc agcttcaatc gcagcaagga
     1741 tagtttcaac accatcttca gttccttcga aacgaggagc gaatccacct tcgtcaccta
     1801 cggcagtttc caaaccacgt gatttaagga ttttcttaag agcgtggaag atttcagcac
     1861 cgtaacgaag ggcttcttta aatgttggcg caccaactgg caagatcatg aactcttgga
     1921 aagcgattgg agcgtcagag tgagaaccac cgttgatgat gttcatcatt ggagttggaa
     1981 gaactttagt gttgaatcca ccaaggtagc tgtaaagtgg gatttcaagg tagtcagcag
     2041 cagcacgagc tacagcgata gacacaccga ggattgcatt cgcacccaat ttacctttgt
     2101 taggagtacc gtcaagtgcg atcatagcac ggtcaatagc ttgttgatca cgtacatcgt
     2161 agccaatgat agcttcagca atgatgttgt ttacgttgtc aacagctttt tgtgtaccaa
     2221 gaccaccgta acgagatttg tcaccgtcgc gaagttcaac tgcttcgtgt tcaccagtag
     2281 aagctcctga tggaaccata ccacgtccga aagcacctga ttcagtgtaa acttctactt
     2341 caagtgttgg gttaccgcgt gagtctagga cttcgcgagc gtaaacatca gtaataattg
     2401 acatttttta ctctccttat gagttaaatt ttttacacct ctataatacc ttaaaacccc
     2461 tcctttttca agaaaaaacg ttatctttgt gcaacttttc cttaacttta taaagtaatc
     2521 gctttctttt gtctgtttta ttctaacttt tatgatatac tgttttcatg acagatttat
     2581 caaaacaatt acttgaaaaa gctcatggtg ggttaaaaat aaatccggat gagcaaagac
     2641 gctatcttgg tacttttgag gaaagagttc ttggatatgt agatattgac acagcaaata
     2701 gccctcagtt agaaaaaggc tttttattta ttttagaaaa ccttcaggaa aaagcagagc
     2761 cactatttgt gaagatttca ccaactatcg aatttgataa gcaagttttc tacttaaaag
     2821 aagcaaaaga aactgatagt caagccacca tagtatctga agagcatatt acttctcctt
     2881 ttggcctggt tattcatagc aatgcaccag ttcaagtaga agaaaaagac cttcgacttg
     2941 cttttccaaa actttgggaa gttaaaaagg aagaaccagc caaaacatcc ttatggaaga
     3001 aatggtttag ctaaatcttg cacatattta ataagtgccc aatattggca gccgtgcgct
     3061 ccagatagag actggcattt ttcaaactat cttctaaagg ttcacttttc tccaaaatag
     3121 aaaagacagc ttggatattt tcaaatggta ggggaggtaa atcttcagca agactaccgc
     3181 aaatagcaat aacaggaact ccaacagggg ttctttttgc aacacctata ggcgctttcc
     3241 cagcaaagct ttgactatca agccttcctt ctccaacaac aaccaagtca gcatctgaaa
     3301 ctttcttatt aaagttgatt aagtccaagc aggtatcaat tccagacacg atacttgcct
     3361 gagcaaaggc acacaaacca ccagcaaggc ctccacctgc tcctgctcct ttaatttcta
     3421 atgttgcagg tgagaatttt tcataaaaat cttggatcgc ctgatctacg actgcaaaca
     3481 tagtcggatg tagacctttt tgattgccaa aagtgtaagt cgcaccttga tgaccacata
     3541 agggactcac gacatctgct agaatatgaa tttgaacacc ttcaggaatt ttatagcaat
     3601 tttctgttga aacagaagct aagtttaata aggattgatc ggaagcaggc aagacatttc
     3661 catccctatc ataaaattga taacctaaac cagcagcaat ccccagtcct ccatcattac
     3721 tggccgtgcc accaacaccg atataaatat ctttaatccc tttagaaatg agatggagaa
     3781 tcaactctcc aataccacaa gtttggattt gaagtggatt tcgtttctct agcggaattt
     3841 ttccaagacc aaccaagtca gctacttcaa atagtgccag ttcccctttt tgaaaatagc
     3901 gcatggcttc tttttgtcca aaagggtctg tcacttggat ccatttttct tttaggtcaa
     3961 gagaatgtcg gatagcatct acagtacctt ctcccccatc accaacaggg cagaggagac
     4021 attctacatc tgctatcgat tgttggaagc ctctttttat tgcttcagct acctgttgag
     4081 ctgtcaagct ttccttaaac gaatccggtg caattacaat cttcatattt tccctcattc
     4141 taaacagtca atcaaaggaa gaacttctaa aaaatccctc ttgtcaacat gatgtggtat
     4201 ttcttttttg agcatttctt tggaacaaaa ggcgattcct aactccgccg acttcaacat
     4261 taatagatta ttgaccccat caccgattgc caccgttctt tctttagaaa gttttagttt
     4321 ctttctccat ttttccagag tttctttttt gacctgggga cttataattt gtccaactaa
     4381 ttttcctgtt aaaagacctt ctttgacttc aagctggttg gcagtgaaat aggcaatacc
     4441 aagggatttt gctaatctct ccaactattg gtgtaaatcc accagacacc agaccaacta
     4501 ggatgccatt cttttggaga atagagatga actctgggac atttagcgat agatgaattg
     4561 agttgaagac gttatcaaag accaaaatag gaagaccttc caacaaggac actctttttc
     4621 ttaaactgct ttcaaagacc aactctcctc gcattgctcg acttgtaatc tgcgaaattt
     4681 ccgcctcatg acctgcctct ctccctaaaa gatcaatcac ttcttctagg attaaggttc
     4741 catctacatc caaaacacac aagcctttta cttgagacat cagttctcct ctctaaacag
     4801 cctaaaaatc gtatgaagtc atcatacgat tttatctatt aattaactaa actatggtac
     4861 aagtcaaggt atgacttgca ggctgtatcc catgagaagt cactctccat agcttgtttt
     4921 tgtaggtttc tccaaatgtc tggatggttt ctatacaagt ccaatgctgt ttggaaagtc
     4981 caatttaacc aataaggaga tagattgtca aagctaaagc cagtaccgct tccttcgatt
     5041 ggattgaaag cgcgaactgt atctcgcaag cctccaactt catggaccaa tggcaaggtt
     5101 ccataacgca tagccatcat ttgagacaag ccacacggtt caaaacgact tggcatgagg
     5161 aagaggtcac aagcagcgta gatttcctga gcaagtttga catcaaaagt gatatttgct
     5221 gatagcttgt ctgggtaaat ctgagcaaac catgagaaag ctccttcaaa ggctggatcg
     5281 ccagttccca aaagaacaat ctgaacatct tcttgcaaga tatggtgaag actttcgacc
     5341 accacatcaa aacctttttg acgtgtcaaa cgagaaacaa ttcccaccag tggaacgtct
     5401 gctctaacag gcaagccaac tctttcttgc aattttgcct tatttttggc tttcccagac
     5461 aaatcttcct gattgaaatg atagtctaaa agagcatccg tctgaggatt ataaagatca
     5521 gcatcaatcc cattcacgat accagatact ttaccagact ccattttaag aatctgatcc
     5581 aaattacatc caaactgact agtcataatt tcatgagcat agctaggtga aacggttgaa
     5641 acacggttcg catagagaat acctgccttc atccagttca gacagttgtt ccatcgaagg
     5701 gtgccatcag cgtaacgttc aaagccaact ccaaacaaat cacccaacat tccttctgaa
     5761 aattgtcctt ggaattctaa attatgaatg gttaaaactg tttcaatgtc ctcataggct
     5821 tgaatccaac ggtatttttc cttcaacaag aaaggaatca tagctgtatg gtagtcatga
     5881 acatggagaa gatcaggaat aaagtcaatc ctttccatag cctcaatggc agccagttgg
     5941 aaaaaggcaa agcgttctcc gtcatcaaaa tcaccgtaaa catgaccacg gaagaaataa
     6001 tattgattgt caataaagta gaaggttaca ccatttaata ctgttttctt aattccacaa
     6061 tactgtctgc gccaaccaac gctcacctca aaatgaagta catcttcaat ctgatttcca
     6121 aatttagcct ctaccatatc atagtagggt aaaatcactg caacttcgtg cccagctttt
     6181 accagtgatt ttggaagagc gccaatgacg tctcccaaac cacctgtttt tgaaaagggt
     6241 gcaccctctg ctgctacaaa taaaattttc atgaatgaat atcctctgtt actttagcac
     6301 ctttcttaac cacaactgga tgttctgcag ttcctcgaat cacaacacca ggctcaactt
     6361 caaccccttt gtccaagata gcatattcga cctgagcccc ttctccaata acaacacgag
     6421 ggaagagcag gctatcttta accaagctat ccttatggac atgaatatta cgtgatagaa
     6481 cagaattagc tacttgacct tcaataatac taccagaggc aaactgagaa gtgcttacct
     6541 tagatgtatt agcatagtaa gttggctctt cgtttttgac ctttgtataa atcttttggt
     6601 ttggtgagaa aagagaatag aatttttgtg attcaagcat atcgatattc gcttgataat
     6661 aagatttaac agagtgaata ttggctagat agcccgtgta ctcgtaggcg aaagctccct
     6721 cttttacagc caaatcccgt aaaacatagc gcaatttctt tggatgttct tttttagctt
     6781 cttcttccaa gtgttcaatc aaccaaggtg tatcaacgac aaagatatct gtagacatat
     6841 tgaacgtttc agctgttgac ttgctatcaa agagtttatg agaaagaaca tggtctgttt
     6901 catctacatc caagattgca tttacttctg aaatatcttt cttagctagt tttttataaa
     6961 ctacagtgat aggctctttt gttgtactat gtaggtggaa aacttggttc aaatcaatgt
     7021 taataagaac atcgcagttg agggcaaccg tttggtttga gccagaacgt ttcaaataag
     7081 taagaagctg ttggtagtat tcttttccaa ctgtactact ttctacacgg gtattgtaaa
     7141 ttcctagata gtaatgacta agaagggttg ataagcccca ctcgcgtcct gaacgaatat
     7201 ggtcaaatac tgagctgata ttatcctgct ggaaaatacc aaagacacta cgaacacctg
     7261 cattagcaag gcttgaaagc gggaagtcaa tcaaacgata tttcccacca aatggcaaac
     7321 ttgctactgg acggtggtcc gtcaatgtcg acatattgtg aaaaccaact gtatttccta
     7381 aaatggcaga atatttatca atcttcatct gttgctaccc ccactacttc attatatcct
     7441 acaacttgta cttcatctgt tccatcaatt tcgacaccgt cagaaataat cgcaccttca
     7501 ccaataatgg cacgtttaat cttagctcct tgaccaatga tagctccact catgataact
     7561 gaatcaagga cttccgctcc ttcgcgaact tgcgcgcctg ttgaaaggat agaatgttta
     7621 acagttccat caacgaaaca tccgtctaca actaatgagt cttccacatg agcatttgcc
     7681 ccgaggaagt ttggtggtga aatcaagttt cttgagtaaa tcttccattg acggttacga
     7741 ctatccaagg cattttctgg agaaatatac tccatgttcg cttcccaaag tgactcaata
     7801 gtaccaacat ctttccaata accactaaat tcgtaagcat aaacactttc acctgactca
     7861 aggtaatttg gaatgacatt tttaccaaag tctgacatgc caaccttgct cttttcagca
     7921 gcgactaaca tattacgaag gcgttgccaa tcaaaaatgt agattcccat agaagctttt
     7981 gtagatttag gttgagctgg tttttcttca aattcaacaa tacgattgtt agcatctgtg
     8041 ttcatgatac caaaacggct tgcttcttta agagggacgt ctaaaactgc tactgtcaag
     8101 ctggcattat tatccttatg agactggagc atatcatcat agtccatttt gtagatgtgg
     8161 tccccagaca aaatcaagac atactcagga ttgacactgt cgatatagtc gatattttgg
     8221 taaatagcgt gactagttcc ctcaaaccaa cgatttcctt cacttgcaga ataaggttga
     8281 agaatagaga cgcctgaatt aataccgtct agtccccagc ttgaaccatt cccaatatgg
     8341 ttgttgagag caagtggttg atactgtgta acgaccccaa cattatgaat ccctgagttg
     8401 gcacagtttg atagggcaaa gtcaatgata cggtagcgcc caccaaattg cacagctggt
     8461 tttgcgatgc tttgagtgag tttaccgaga cgagttcctt gcccaccagc aagaatcaaa
     8521 gctaacattt catttttcat tttctactcc tttttggttt taatttgtga cggttttagt
     8581 agatttcaag cgacgtttga ttttccatac acttgctccc atagccggta gagtaaaggt
     8641 taaggtctgc tcataatctt tccatagtcc ttcttgcgtt tgaacagttt gattatgttc
     8701 tttccaaaca cctccccact cttccaactc agtattccat acttcttcgt aaattcctgc
     8761 aacgggtagt ccgattgtaa aatctttccg ctcaacaggt accatgttaa agatacagac
     8821 taacatttct ccctttttac ccttacgaat aaaggaaaga acactctggt ctcgattatc
     8881 cgcatcaatg atttcaatac catcatagct ggtatcaatt tcccacagac agcgatgatc
     8941 tttgtaaaac tggtttagct gagaagcgaa atacttcatc ttagcattca ttgggtcttc
     9001 taggttagac cattccaact gttcttcaga tttccattct aggaattgac cgtattcgct
     9061 acccatgaag agcaatttct taccagggtg acaaatttgg tacgtataga gattgcgcaa
     9121 gcctgcaaat tgattgtaac gatctcccca catcttatgc atcatactct tcttgccatg
     9181 aaccacttca tcgtgcgaga atggcaagag ataattctcc ttgaaaacat acataaagct
     9241 gaaagtcacc aggttaaagt catatttacg ataaatcgga tcttcttcgt agaaacggag
     9301 gatatcattc atccagccca tgttccattt gtagtcaaat cctagaccac caatctcttt
     9361 cattcccgta atcttggttg cagacgaact ttcttctgca atcatcatca catctggata
     9421 ttctaactta ataacttcat tcaagcgttg aagaaaataa taaccttcat agttgagatt
     9481 tccgccatct ttattaggtg tccatggagc atcatcatag tccaaataga gcatgttgct
     9541 aacagcatcc acacgaatac catccaaatg atagacatca atccaatgct taatgcaaga
     9601 aattaagaag gactggactt cattttttcc aaggtcaaaa ttaagggcac cccaaccatg
     9661 gttatgagcc ttattatggt cttggtattc aaaagtcggt gtcccatcat aataggctaa
     9721 ggcatcatcg ttgatggtaa agtgacctgg tacccagtcc acaataaccc caatattatg
     9781 ggtatgacac tcctcgacaa aatcttgaaa ctcctctggt ctgccataag catgctctaa
     9841 agcgaagtaa cccataagct gataccccca actcaagccc aaaggatggg acatcaaggg
     9901 cataaactca atatgagtat agttcatttc aacgagataa ggaatgagtt catccttgag
     9961 ctgggcaaaa ctataaggac tgccatcaga atttcttttc catgatccag cgtgaacttc
    10021 ataaatattg acaggacgct cttcaaagcc ccaacgtttt cttcgtgcca gccaaagtcc
    10081 atccttccat ttcttctcag gaagctctgt taagattgcc cctgttcctg gacgagcctc
    10141 atacctgaca gcaaaagggt caatcttcat cagttgatga ccattttgac gtgtgacatg
    10201 atatttgtaa atatgccctt cttgagccat attggtaaag acttcccaga ccccaaagtc
    10261 atttcttacc attggaatct gattttcaat ccaattggta aaatcaccaa ccaagtgaac
    10321 agcctgagca ttaggtgccc aaacacggaa ggtatagcca tgctctccat ttagttcttc
    10381 cctatgtgct cctagataat gttggagata aaaattttca cccgtcataa aggtttttaa
    10441 tgcttctcta ttatccatat actccccttc tcctgtaagc gttttctatg tttttattat
    10501 actacctttt tagagaagat tcaagtaaat tactatactt ctttaattat tttgaaaatc
    10561 tacaacaagt tcacttactc gttcaattgt aaatcaatat tttttcaaaa aattgcgaaa
    10621 acgcctttct
//
LOCUS       DAVKBC010000054        10043 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVKBC010000054 DAVKBC010000000
VERSION     DAVKBC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10043
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.054"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            537..1580
                     /locus_tag="VWX64_001781"
     CDS             537..1580
                     /locus_tag="VWX64_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU9191202.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1747..3834
                     /gene="topA"
                     /locus_tag="VWX64_001782"
     CDS             1747..3834
                     /gene="topA"
                     /locus_tag="VWX64_001782"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU9191203.1"
                     /translation="MATATKKTKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLTIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            4055..4414
                     /locus_tag="VWX64_001783"
     CDS             4055..4414
                     /locus_tag="VWX64_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU9191204.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4507..5139
                     /locus_tag="VWX64_001784"
     CDS             4507..5139
                     /locus_tag="VWX64_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU9191205.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            5183..5839
                     /locus_tag="VWX64_001785"
     CDS             5183..5839
                     /locus_tag="VWX64_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU9191206.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5858..6490
                     /locus_tag="VWX64_001786"
     CDS             5858..6490
                     /locus_tag="VWX64_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU9191207.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEETINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKVVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            6518..6952
                     /locus_tag="VWX64_001787"
     CDS             6518..6952
                     /locus_tag="VWX64_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEU9191208.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6964..8000
                     /gene="leuB"
                     /locus_tag="VWX64_001788"
                     /pseudo
     CDS             6964..8000
                     /gene="leuB"
                     /locus_tag="VWX64_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            7997..8266
                     /locus_tag="VWX64_001789"
     CDS             7997..8266
                     /locus_tag="VWX64_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU9191209.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYYIWR"
     gene            8270..8629
                     /gene="leuD"
                     /locus_tag="VWX64_001790"
     CDS             8270..8629
                     /gene="leuD"
                     /locus_tag="VWX64_001790"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU9191210.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8791..9359
                     /locus_tag="VWX64_001791"
                     /pseudo
     CDS             8791..9359
                     /locus_tag="VWX64_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            9731..>10043
                     /locus_tag="VWX64_001792"
     CDS             9731..>10043
                     /locus_tag="VWX64_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9191211.1"
                     /translation="MVSKQTFIDRIKKEFPDAIENQTKSYISFQVKNRKGKLQNFIEI
                     NFQNKGIKIAVLSKSLHDSDILLFNKKPDSFGWTLDAEYFIEDENSLNEILPFINKSY
                     EF"
BASE COUNT         3170 a         1728 c         2188 g         2957 t
ORIGIN      
        1 aacaactcta tcaggaaagt caaattaatt tatagaaata ttttagcagc caaggtgcac
       61 tgttatagat tcaatacact ataatttagt gtaattgaga aaggagaaat gattgtgatt
      121 gatgttggct aggttatttt caatgattcc taccgtctca aatcttgtca gtaaggaaaa
      181 ataaattctt caaaagtaga gattacaagg cttgtttaag aaagaattca aagaccttga
      241 caaataaaaa taaaatggtt attataagaa atggtctaaa atagatgatg atacttttcg
      301 aaaatctttt tacgtcagct cagctttgcc ttgctgtgtt ttgagcaagc tacggttagc
      361 ttccgagttt gattttcatt tactagaaat gaaactgatg agagatatca gtagacattt
      421 gagtcaggat attatggaaa atgataaaaa gagctcgtga gattggcata tcagactact
      481 aaagtattga gtttgttagg attttagcga ctagttagct gggaaaggaa gatattgtga
      541 caaataataa actgtattcg ttgatagaat ttagaaataa aatatatgaa gaattagaac
      601 tttccagaag tgatttagcg attttactat gtgccatgct tatcgcctct atcggattaa
      661 atatggattc gactcccgtg attattggag ccatgttaat ctctcctttg atgacaccta
      721 ttctgggagt ggggctctct ctagctatat ttgattttaa attgttaaga aaatctttta
      781 aaatattagc tattcaaatt cttgccagtt taatagcttc aacactttat ttttatcttt
      841 ctcccatttc gtatgctagt tcggaaattg ttgctagaac ctctccgact atttgggatg
      901 ttctcattgc ttttgtagga gggatagcag gtattattgg tgctaggaaa aaagagacca
      961 ataatattgt tcctggtgtt gctattgcaa ccgccttgat gcctcctctt tgtacagtag
     1021 gttatgctat tgcttctgct aatctaaaat ttatcatagg ctcctcttac ctattcctca
     1081 tcaattgtag ctttattgtc attgcgactt atataggtgt taggttgatg atggttaaga
     1141 aacattattt taaagataat gaagaagact ctaaaatgcg taggattttg cttctagttg
     1201 ctgttttgct gatgattccg agtttcatct ctgcaacgac tttagtgaga gaaacgttga
     1261 aaaaagagtc ccttaagaaa tttatatcag agcagtttca ggggcataat attttgaaaa
     1321 aaacctattc taaaaagact cataccctaa agctaaccat ttcaggaaat tatttgacag
     1381 aagaagaact cgatatgatt tcaagtaaga gaggtgacta tggtttaagt gatgtttctg
     1441 ttcaagtttc acaattgtct gattcagaac aacttagtaa ggaagaactg gtggagtatt
     1501 tcttccagta tatcaaggat aaggaagcaa aagaaaagga aaaagctaat aagttttata
     1561 cagagtctga ggagcaataa tttcttgaga atagctggtt tttctcgtga gtcttctatg
     1621 tatatcaaag gaagactgag gttttaagta taaaactttt cttctattat agtagctaag
     1681 tcttgacagg gttcaaaaaa tggtttacac tttataaagt ttattacttt gaaaaggtgt
     1741 gatactgtgg ctacggcaac aaaaaagaca aaatcaacag ttaaaaaaaa tctagtcatc
     1801 gtggagtcgc ctgctaaggc caagacgatt gaaaaatatc taggcagaaa ctacaaggtt
     1861 ttagccagtg tcgggcatat ccgtgatttg aagaaatcca gtatgtccgt cgatattgaa
     1921 aataattatg aaccgcaata tatcaatatc cgaggaaaag gccctcttat caatgacttg
     1981 aaaaaagaag ctaaaaaagc taataaagtt tttctcgcga gtgacccgga ccgtgaagga
     2041 gaagcgattt cttggcattt ggcccatatt ctcaacttgg atgaaaatga tgccaaccgt
     2101 gtggtcttca atgaaatcac caaggatgca gtcaaaaatg cttttaaaga acctcgtaag
     2161 atcgatatgg acttggtcga tgcccaacaa gctcgtcgga tcttggatcg cttggtaggg
     2221 tattcgattt cgcctatttt gtggaagaag gtcaagaagg gcttgtcagc aggtcgcgtt
     2281 cagtccattg cccttaaact catcattgac cgtgaaaatg aaatcaatgc cttccagcca
     2341 gaagaatact ggacagttga tgctgtcttt aaaaagggaa ccaaacaatt tcatgcttcc
     2401 ttctatggag tagatggtaa aaagatgaaa ctgaccagca atgacgaagt caaggaagtc
     2461 ttgtctcgtc tgacgagtaa agacttttca gtagatcagg tggataagaa agagcgcaag
     2521 cgcaatgctc ctttacccta taccacttca tctatgcaga tggatgctgc caataaaatc
     2581 aatttccgta ctcgaaaaac catgatggtt gcccaacagc tctatgaagg aattaatatc
     2641 ggttctggtg ttcaaggttt gattacctat atgcgtaccg attcgactcg tatcagtcct
     2701 gtagcgcaaa atgaggcggc aagcttcatt acggatcgtt ttggtagtaa gtattctaag
     2761 cacggtagca aggtcaaaaa cgcatcaggt gctcaggatg cccatgaggc tattcgtccg
     2821 tcaagtgtct ttaatacacc agaaagcatc gctaagtatc tggacaagga tcagctcaag
     2881 ctatataccc ttatctggaa tcgttttgtg gctagccaga tgacagcggc cgtttttgat
     2941 accatggctg ttaaattgtc tcaaaaaggg gttcaatttg ctgccaatgg tagtcaggtt
     3001 aagtttgatg gttatcttac catttataat gattctgaca agaataagat gttaccggac
     3061 atggttgttg gagatgtggt caaacaggtc aatagcaaac cagagcaaca tttcacccaa
     3121 ccgcctgccc gttattctga agcaacactg attaaaacct tagaggaaaa tggggttgga
     3181 cgtccatcaa cctacgcgcc aaccattgaa accattcaga aacgttatta tgttcgcctg
     3241 gcagccaaac gttttgaacc gacagagttg ggagaaattg tcaataagct catcgttgaa
     3301 tatttcccag atatcgtaaa cgtgaccttc acagctgaaa tggaaggtaa actggatgat
     3361 gtcgaagttg gaaaagagca gtggcgacgg gtcattgatg ccttttacaa accattctct
     3421 aaagaagttg ccaaggctga agaagaaatg gaaaaaatcc agattaagga tgaaccagct
     3481 ggatttgact gtgaagtgtg tggcagtcca atggtcatta aacttggtcg ttttggtaaa
     3541 ttctacgctt gtagcaattt cccagattgc cgtcataccc aagcaatcgt gaaagagatt
     3601 ggtgttgagt gtccaagctg tcatcaggga caaattattg agcgaaaaac caagcgtaat
     3661 cgcctattct atggttgcaa tcgctatcca gaatgtgaat ttacctcttg ggacaagcct
     3721 gttggtcgtg actgtccaaa atgtggcaac ttcctcatgg agaaaaaagt ccgtggtggt
     3781 ggcaagcagg ttgtttgtag caaaggcgac tacgaggaag aaaagattaa ataagaggag
     3841 gggcccgaaa gtaaatttca ggctcctttt ggttagaact tgacaaaata catcatttta
     3901 tgcgaaacta gaagaagatt attttatact cagtgagaat caaagagcaa attagaaagc
     3961 tagtcgcagg ttgctcaaag cactactttg aggttgaaga tggaagctga cctggtttga
     4021 agagattttc gaagagtatt aactaggaga agttatgcgt cttatctatc taattattgg
     4081 ttttttatcg ctggccttgg ctattgttgg ggttgtttta cccttgttac ctacaacacc
     4141 tttccttttg ttgtctattg cttgtttctc cagaagttcc aagcgattcg aagactggct
     4201 ttatcatacc aagctctatc aaacatatgt agctgatttt cgcgagacta agtctattac
     4261 gcgtgaacga aagaaaaaaa tcatcgtctc tatctacgtc ttgatgggaa tttctattta
     4321 ttttgcacct cttttaccag tcaaaatcgg tctgggtgct ttgaccatct ttatcactta
     4381 ttatcttttc aaggtcattc cagacaaaga atagttaaaa cagtagttat ttgccttgat
     4441 aaaattgaaa gcatattcat aacaatatga tataataaat ttgaagtaat attcaaggag
     4501 aatcaaatga tttacgaatt ttgtgctgaa aatgtgactt tacttgaaaa agcgatgcag
     4561 gctggagctc gtcggattga actctgtgat aatctagcag ttggtgggac aacacccagc
     4621 tatggagtga ctaaggcagc ggttgaactg gcagctaact acgatacaac catcatgacc
     4681 atgattcggc cacgtggtgg tgactttgtc tataatgacc tagaaattgc tatcatgcta
     4741 gaagacattt gtttgactgc tcaggctgga agtcaagggg ttgtatttgg agctttaact
     4801 gctgataaaa agttggataa gcctaatctg gaaaagttaa ttgctgcatc aaaaggaatg
     4861 gaaattgtct ttcacatggc ctttgatgaa ctaagtgatg aagatcaacc ggaagctatt
     4921 gactggctca gtcaagccgg tgtcactcgt atcctaactc gtgctggtgt gtctggcgac
     4981 tccttagaaa aacgttttgt tcactatcac agaattttgg agtacgctaa aggtaaaatt
     5041 gaaattctac caggtggggg gattgacctt gacaaccgtc aaacctttat tgaccaggtg
     5101 ggggtaacac aattgcatgg tactaaggtt gttttttaaa aaatagaaag gaactgctag
     5161 ccttgggtag cagttttcac ttatgtttga aatttttaaa tcctatcaat ttaatcaaga
     5221 aaaggctcat gattatggtt ttatagaaaa tagcgaagtc tggacatata gttgccagat
     5281 tttgcaaggt gactttgtca tgactgtgtc catcactgct gataatgtga actttcaagt
     5341 ctttgaccaa gagactggtg acctttatcc tcacgttcat atggaaagca tgaggggaag
     5401 ttttgtcgga aatgtccgtg aggcttgtct ggagattctt taccagattc ggaaggcttg
     5461 ttttgatgtg caagatttta tctgtcatca gactaagcgt atcatgactc aagttcagga
     5521 aaagtatgga aaccagttgg agtatctgtg ggaaaaatcg cctgatacag ctgtattgcg
     5581 ccatgaaggc aatcaaaagt ggtatgccgt cttgatgaaa atctcttgga ataagctgga
     5641 aaagggcaga gaaggacaag tggaagcagt caacctcaag catgaccaag tagctaattt
     5701 gctttcacaa aaggggattt atccagcctt ccatatgagc aagcgctact ggattagtgt
     5761 gtcccttgat gatactttat cagatgaaga agtactggaa ttgatagaaa aaagttggaa
     5821 cttaacctct aaaaaatgaa atattttaat aattttcatg aactttcaat tagctaaata
     5881 ttctttactg aagaaatttt cagaaaatat aggatttacc acaccagagg aatgtggtgc
     5941 catcttcaaa tacctgattg agaatgtcaa gacggatcgt cagatcatct attcgcctca
     6001 ctgtcatgat gacctcggaa tggcagtggc aaatagcctt gctgctgtca agaatggtgc
     6061 aggacgtgtt gaagagacta tcaatggtat tagggagcga gctgaaaatg ctgctttgga
     6121 agaaattgca gtggctctca atattcgcca agattactac caagtagaaa ccagtattgt
     6181 cctaaatgag accatcaata cgtcagaaat ggtttctcgc ttctctggta ttccagttcc
     6241 taaaaacaaa gtcgtcgttg gtggcaatac cttctcccac gaatctggta ttcaccaaga
     6301 tggagtcctt aaaaatcctc tcacttatga gatcatcaca cctgaattgg ttggtgttaa
     6361 gattccgctt ggaaaattat ctggtcgcca tgcttttgtt gagaaactga gagaattggc
     6421 cctagatttt acagaagagg atatcaaacc actctttgct aagttcaagg cactggccga
     6481 taagaagtaa gaaatcacag atgcagatac tcgagctttg gtagctggaa ccatggttga
     6541 aaatccagaa ggcttccact ttgatgattt acaacttcaa actcatgcag ataatgacat
     6601 tgaagcgctc gttagcctag ccaatatgga tggtgagaaa gtcgaattta atgcgacagg
     6661 gcaaggttcc gttgaagcaa tctttaacgc tatcgataag ttctttaacc aatctgttcg
     6721 tttggtgtcc tacactatca atgcggtaac agatggaatc gatgcccagg atcgggtttt
     6781 ggtcactgtt gaaaacagag atacagaaac catctttaat gcagcagggc ttgattttga
     6841 tgtgttgaag gcttctgcta ttgcctatat aaacgctaat acctttgttc aaaaagagaa
     6901 tgcaggtgag atgggacgca gtgtttctta ccacgatatg cctagtgtgt aaaggagaag
     6961 gctatggcaa agaaaatagt agctctagta ggagacggaa ttggcccaga aatcatggag
     7021 gctggtttag aagttctgga ggctctagct gaaaaaacag gttttgacta tgagattgac
     7081 agacgaccgt tcggaggtgc agatattgat gcagcaggac ctcccttacc tgatgaaacc
     7141 cttaaggcaa gtagggaagc agatgctatc ctactagtag ctatcggtag tcctcagtat
     7201 gatggagtag cggttcgccc tgaacaaggc ctgatggctc tccgtaagaa ctcaatcttt
     7261 acgctaatat tcgtcctgta aaaatctttg acagtctcaa gtatttgtca ccactcaaac
     7321 cggaacgaat ttctggtgta gactttgtcg tggtgcgtga attgacaggc gagatttact
     7381 ttggagatca tattcttgaa gagcgcaaag cgcgtgatat caacgactat agctatgagg
     7441 aagtggagcg gattattcgc aaagcctttg aaattgcaag aaatcgcaga aaaatcgtta
     7501 ctagtatcga taagcaaaat gttctagcga cctcaaaact ctggcggaaa gtagctgagg
     7561 aagtcgcaca ggatttctca gatgtaacct tggaacacca gctggtagac tcagctgcta
     7621 tgcttatgat taccaatcct gctaagtttg atgttattgt aacggagaat ctttttggag
     7681 atattttatc tgatgaatca agcgtcttat ctggtacact tggggttatg ccatcagcca
     7741 gtcattctga aaatggacca agtctctatg aacctattca cggttcagca cctgatattg
     7801 caggtcaagg aattgccaat cctatttcca tgattttatc agttgtcatg atgttgagag
     7861 atagtttcgg acgttatgag gatacagagc gtatcaaacg tgctgttgag acaagtctgg
     7921 cggcaggaat tttaacgaga gatataggag gtcaggcttc aacaaaggaa atgatggaag
     7981 ctattattgc aaggttatga agttagacga aaaaattact ctagtccttt tgatttggaa
     8041 tgtcatcatt ttcttgattt atggcattga caaattcaag gcaagaagaa gagcttggcg
     8101 catcccagag aaaatcttac tcattttagc ccttacttgt ggtggttttg gggcctggtt
     8161 agctggaatc acttttcacc acaagactcg aaaatggtac tttaaaacag tttggtttct
     8221 tgggatggtg accacactag tagccttata ttatatttgg aggtaatgga tggcagggtc
     8281 ttcgagggaa cacgctgctt gggctctagc ggactatggt tttaaggtcg tgattgcagg
     8341 atctttcggt gacattcatt acaataatga actcaataat ggcatgttgc caatcgttca
     8401 gcctagagag gttagagaga aactagccca gttaaaacca accgaccagg taactgtgga
     8461 cttggaacaa caaaaaatca tctcaccagt tgaagaattc accttcgaga tagatagcaa
     8521 gtggaaacat aaactcctaa atagtttgga tgatatcggt attaccttgc agtatgaaga
     8581 gttgattgct gcttatgaaa aacaacgacc agcctactgg caggattaga aaaaatagaa
     8641 aaggaaatat agtaaactga aataagatgt aaacaaatga attggagctt aacatcaatt
     8701 tccagcaatt ttttagaaac tacagtggac tattctggat tcaacacatt ataaaattat
     8761 gacaaaacac attcacaaga aggctacgac attttaaaag gtgagggcgg atgtatcgtt
     8821 tgccctacta aagttggtta cattatcatg accagcaaca aggcaggact tgagcgtaag
     8881 ttcgcagcca aagaacgtaa gcgtaacaaa ccaggtgttg ttctctgcgg tagcatggat
     8941 gaactttgcg ctttagcgca actcaaccca gaaattgaag cattctacta aaaacattgg
     9001 gatgaagata ttcttcttgg ttgtatcctt ccttggaaac cagaagcctt tgaaaaactc
     9061 aaagcatacg gggatggccg tgaagaactt atgactgatg tacgtggtac tagctgtttt
     9121 gttatcaagt ttggaaaagc aggtgaacaa ttggctgcca agctttggga agaaggtaaa
     9181 atggtctacg cctcatctgc ttcaatgaca aaacgactga aactcgctat gagcaaggtg
     9241 taatggtgtc tatggtcgat aaggacggca aactcatccc agaacaagga ggagcacgtt
     9301 caacctcacc agcaccagtt gtgatccgta aagggcttga cattgatata gtaaaatgaa
     9361 gtaagatcag cacaaagtaa tcaggacagt caaatcgatt tctaacaatg ttttagaagt
     9421 agaggtgtac tattctagtt tcaatctact ataaaatcat gatgcacctg tcagatactt
     9481 ttaactcatg ggactaccgt cagggtgagt attattaaga taaaaaaaga agtctagtgt
     9541 tatgagatat taaagctcct aacactgggc tttttgttta gaatttcttt tatttttcta
     9601 taggatatga tatgctagat gcagaatata ttaatagaat gtagtttctg caaagtaaaa
     9661 tatcttactt tgaacgaaac aaatataatt taagtctaac aataaatttt taataagcaa
     9721 ggaaaacaca atggtttcaa aacaaacttt cattgacagg ataaaaaaag aattcccaga
     9781 tgcaattgaa aatcaaacaa aaagttatat ttcttttcag gttaaaaata ggaaagggaa
     9841 gttacaaaat tttatagaga ttaattttca aaataaagga ataaagattg ccgttctctc
     9901 taagagtctt catgattcag atattttgtt gtttaataag aagcctgatt cattcggttg
     9961 gacacttgat gctgagtatt ttattgagga tgaaaattca ttaaatgaga ttttaccttt
    10021 tataaataaa tcttatgaat ttg
//
LOCUS       DAVKBC010000055         9853 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVKBC010000055 DAVKBC010000000
VERSION     DAVKBC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.055"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..362
                     /locus_tag="VWX64_001793"
     CDS             <1..362
                     /locus_tag="VWX64_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9191212.1"
                     /translation="TYREALITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKV
                     VVVRLEKSVTFHNMIAPDKEVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLS
                     KISEPEKLYAYIAEAIA"
     gene            400..702
                     /locus_tag="VWX64_001794"
     CDS             400..702
                     /locus_tag="VWX64_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9191213.1"
                     /translation="MIKILAACGAGVNSSYQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIRLPAKQNMV"
     gene            710..1514
                     /locus_tag="VWX64_001795"
     CDS             join(710..1078,1080..1514)
                     /locus_tag="VWX64_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU9191214.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKELANDSGKKKFHAMKAQEIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLIAEDKAYNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHKLEF"
     gene            1563..2027
                     /locus_tag="VWX64_001796"
     CDS             1563..2027
                     /locus_tag="VWX64_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU9191215.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2184..2609
                     /gene="lacA"
                     /locus_tag="VWX64_001797"
     CDS             2184..2609
                     /gene="lacA"
                     /locus_tag="VWX64_001797"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU9191216.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2640..3155
                     /gene="lacB"
                     /locus_tag="VWX64_001798"
     CDS             2640..3155
                     /gene="lacB"
                     /locus_tag="VWX64_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU9191217.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHVETHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3166..4095
                     /locus_tag="VWX64_001799"
     CDS             3166..4095
                     /locus_tag="VWX64_001799"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU9191218.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            4097..5077
                     /gene="lacD"
                     /locus_tag="VWX64_001800"
     CDS             4097..5077
                     /gene="lacD"
                     /locus_tag="VWX64_001800"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU9191219.1"
                     /translation="MALTEQKRARLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5311..6147
                     /locus_tag="VWX64_001801"
     CDS             5311..6147
                     /locus_tag="VWX64_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9191220.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6183..6500
                     /locus_tag="VWX64_001802"
     CDS             6183..6500
                     /locus_tag="VWX64_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9191221.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6500..8191
                     /locus_tag="VWX64_001803"
     CDS             6500..8191
                     /locus_tag="VWX64_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9191222.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            8406..9812
                     /gene="lacG"
                     /locus_tag="VWX64_001804"
     CDS             8406..9812
                     /gene="lacG"
                     /locus_tag="VWX64_001804"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU9191223.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVNNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
BASE COUNT         3132 a         1777 c         2038 g         2906 t
ORIGIN      
        1 caacttatcg tgaagccttg atcacgcgtg aaaagtcatt tccaactggt ttagatatgg
       61 aatttctagg aaaggacttg ccaaatgtag cgattcctca cacagatatt gttcataatc
      121 tagctgaaaa agtggtggtt gttcgattag aaaaatcagt aacttttcac aatatgatag
      181 ctcctgataa ggaagtagaa gtatccctac tcttctttat cattaacaat tcaagttcaa
      241 gtcaaacaaa tattctggct cagttgatgg actttttcac aggaaatgga catcttgaag
      301 atttatcaaa aatttccgaa ccagaaaaac tttatgctta cattgctgaa gcaatcgctt
      361 aatcttgtct attaaaaaat aaaatcggag gaaatccaaa tgattaaaat tcttgctgcc
      421 tgcggtgcag gtgttaactc aagttaccaa attaaaagtg ctctagaaga agaactttca
      481 aaccgtggtt atgatgttca ctgtgatgca gtcatggtga aagatgtaaa cgaagacctt
      541 atgaaaggtt acgatatctt tacaccaatc gctgcaacag atcttggttt tgaaccaggt
      601 atcccagtta tcgaagctgg gccaatctta ttccgtatac cagcaatgag cgctccagta
      661 tttgacaata ttagactccc tgcgaaacaa aatatggtat agtagttcta tgaatgatga
      721 agcaagtaaa caactaactg atgcacgatt taagcgtctt gttggtgttc agcgtaccac
      781 ttttgaagag atgttagctg tattaaaaac agcttatcaa cttaaacacg caaaaggtgg
      841 acgaaaacct aaattaagcc tagaagacct tcttatggcc actcttcaat atgtgcgaga
      901 atatcgaact tatgaagaaa ttgcggctga ttttggtatc cacgaaagca acttactccg
      961 tcggagccaa tgggttgaag taactcttgt tcaaagtggt gttacgattt caagaactcc
     1021 tctcagttct gaggacacgg taatgattga tgcgacggaa gtacaaatca atcgccctaa
     1081 aaaaagaatt agcgaatgat tctggtaaaa agaaatttca cgctatgaag gctcaagaga
     1141 ttgtcacaag tcaagggaga attgtttctt tggatatcac tgtgaactat tgtcatgata
     1201 tgaagttgtt caaaatgagt cgcagaaata tcggacaagc tggtaaaatc ttggctgaca
     1261 gtggttatca agggctcatg aagatatatc ctcaagcaca aactccacgt aaatccagca
     1321 aactcaagcc gctaatagct gaagataaag cctataacca tgcgctatct aaggagagaa
     1381 gcaaagttga gaacatcttt gccaaagtaa aaacgtttaa aatgttttca acaacctatc
     1441 gaaatcatcg taaacgcttc ggattacgaa tgaatttgat tgctggtatt atcaatcata
     1501 aactagaatt ctagttttgc aggaagtcta ataaagaaac tagcaaggtc aggccttact
     1561 ttattggtgg acatccagga tttaattgtc ttctacttga tgatgaagtc tatgaagatt
     1621 attatctaga gtttgagaaa gaagagattt gctctgttcc acgtcctttc ccagaaacag
     1681 gtatgttgga tttccaagat agaagtccat ggctagaggg acaaaaagaa atagatctta
     1741 gttatgatct tttcagcaca gatgcagtga ctttggatga attgcaatct cgaacaattg
     1801 cccttcgttc tcttaaacat gataagggat tgaaagtgca ttttgcagaa tttccaaacc
     1861 tcatcatctg gtcaactttg aacaagggac ctttcattac ctttgaacca tggtctggct
     1921 tgtcaacatt ccttgaagaa ggagatcatt tagaagataa gaagaatgtt tgtctcttag
     1981 aagccaatca ggttgaagaa ttagggtttg agatagaagt tttataaaaa agtaaaaaat
     2041 aaataacaaa aacaaacaca aactgttgac ttcttcaaac aatagtagta tattatgttt
     2101 gtgaggacta attgactgtt ttttaaagac agccaataca ctgctggaat ccagcataga
     2161 aaaaataaaa aggagtatac aatatgtcta ttgttatcgg tgcagatgct gcaggtttga
     2221 gattgaaaga agttgtgaaa gacttcttag aaaaagaaaa cttccacctt gtggatgtta
     2281 cagctgaagg tcaagacttt gttgatgtga ctctcgctgt tgctgcagaa gtaaacaaag
     2341 aagaacaaaa ccttggtatc gtgattgatg cttatggagc tggtccattt atggttgcaa
     2401 ctaagatcaa aggaatggtt gctgcagaag tatctgacga acgttcagct tatatgactc
     2461 gtggccacaa caactcacgt atgatcacta tgggggcaca acttgttggt gatgaattgg
     2521 ctaaaaacat cgctaaagga tttgttaatg gtaaatacga cggtggacgt catcaaatcc
     2581 gggttgacat gttgaacaaa atgggctaat tagattacag taagaaaggt aagttaaaaa
     2641 tgagaattgc aattggatgc gaccacatcg taacagatga aaaaatggcg gtttcagaat
     2701 ttttgaaatc aaaaggatat gaagtcattg actttggtac atatgaccat acacggactc
     2761 actacccaat ctttggtaaa aaagtagggg aagctgtaac tagcggccaa gctgatcttg
     2821 gagtatgtat ctgtggtact ggtgttggta tcaacaacgc tgtaaataaa gttccaggtg
     2881 ttcgctctgc cttggttcgt gatatgacaa cagcccttta tgctaaagaa caattgaacg
     2941 ccaacgttat cggttttggt ggtaagatta ctggtgaatt gctcatgtgc gatatcatcg
     3001 aagctttcat ccatgctgaa tacaaaccat ctgaagaaaa caaaaaattg attgcgaaaa
     3061 ttgaacatgt tgaaacacac aatgctcaac aaacagatgc aaacttcttc actgaattcc
     3121 ttgaaaaatg ggatcgcgga gaataccacg actaagaggt gacctatgat tttaacagtc
     3181 acaatgaacc catccattga tatttcctat cccttggatg agttgaagat tgatactgtc
     3241 aatcgtgtgg tagatgtaac caaaacggct ggtggtaaag ggctcaatgt tacacgcgta
     3301 ctttcagaat ttggcgattc tgttcttgct actggtttag taggtggcaa acttggtgag
     3361 tttttggttg aacatatcga taatcaagta aagaaagatt tcttctcaat tcagggagaa
     3421 actcgtaact gtatcgctat tctccacgga gacaaccaaa cagaagttct tgaaaaaggt
     3481 cctgaagtat tggaacagga aggtcaagac tttttggaac atttcaaaaa actcttggag
     3541 tcagttgaag tagtggccat ctcaggtagt ctgccagctg gccttccagt tgattactat
     3601 gcgagcttgg tagaacttgc taatcaagct ggcaagcctg tagtcttgga ctgctcaggt
     3661 gcagcacttc aggctgttct tgaatcaccc cataaaccaa cagtcatcaa accaaataat
     3721 gaagaattgt ctcagcttct tggaagagaa gtttctgagg atttggatga attaaaagaa
     3781 gtacttcaag aacctttgtt tgcagggatt gaatggatta tcgtttcact tggtgccaac
     3841 ggtacttttg ccaaacatgg tgacactttc tacaaggtag atattcctag aattcaggtg
     3901 gtaaatcctg ttggatctgg agactctact gtggcaggaa tttcttcagg acttcttcac
     3961 aaagaatcgg atgcagaatt actcatcaag gcaaatgtcc ttggtatgct caatgctcaa
     4021 gaaaaaatga ctggtcatgt caacatggcc aactatcaag ttctatatga tcaattaata
     4081 gtaaaagagg tataaaatgg ctttaacaga acaaaaacgt gcacgcttag aaaaactttc
     4141 tgatgaaaat ggtatcatct cagctcttgc atttgaccaa cgtggtgctt tgaaacgcct
     4201 catggctcaa caccaaacag aagaaccaac tgtggctcaa atggaagaac tgaaagtctt
     4261 ggtagcagat gaattgacta aatacgcttc atcaatgctt cttgaccctg agtatggact
     4321 tccagcaact aaagctcttg atgaaaaagc tggtcttctc cttgcttatg aaaaaacagg
     4381 ttatgacaca acaagtacaa aacgcttgcc agactgcttg gatgtttggt ctgcaaaacg
     4441 tattaaagaa gagggtgcag atgcagttaa attcttgctt tactatgatg tagatagttc
     4501 agacgaactc aaccaagaaa aacaagctta tatcgagcgt atcggttctg agtgtgtggc
     4561 tgaagatatc ccattcttcc ttgaaatcct tgcttacgat gaaaaaattg cagacgcagg
     4621 ttctgtagaa tatgcgaaag taaaaccaca caaagttatc ggtgctatga aagtcttttc
     4681 agacccacgc tttaacattg atgtcttgaa agttgaagtt cctgttaaca ttaaatatgt
     4741 tgaaggcttc gctgaaggtg aagtggttta cacacgtgaa gaagcagcag ccttcttcaa
     4801 agcgcaagat gaagcaacga acttgccata catttacttg agtgctggtg tatcagctaa
     4861 actcttccaa gatactcttg tatttgctca tgaatcaggt gcaaacttta acggagttct
     4921 ttgtggccgt gctacatggg caggatcagt tgaagcttac atcaaagatg gtgaagcagc
     4981 agctcgcgaa tggcttcgca caactggatt tgaaaacatt gatgagctca ataaagttct
     5041 tcaaacaaca gcgacttcat ggaaagaacg tgtgtaagaa agtcctccta gtttaggaac
     5101 atgaatctaa aaaaatttaa aaaaagttgt atgtaaaggt ttacaaaata acttacttgt
     5161 gctatactta aatcacaagt taatacaagg tgagtgttac taagtaatat taggcatgat
     5221 cacaggtgaa ttagaaatca gctgattttc tagttcattt gtggtcattt tttgtactca
     5281 tatactttta agatataaaa ggaggttgac atgtatcgaa ttctaaatcc aatgaatcac
     5341 aatgtctcgc ttgtcagaaa tgataaggga gaagaggtga ttgtaattgg taaggggatt
     5401 gcattcggaa agaagaaggg ggatttgatt gctgaaaatc aggttgagaa aatctttcgg
     5461 atgaagaccg aagagtccag agaaaacttt atggctcttc tcaaagatgt tccgcttgat
     5521 tttatcacag tgacctatga aatcattgat aagctatcaa agaaatatca ttatccgatt
     5581 caagagtatc tctatgtaac cttgacagat catatttact gttcttatca agctctaact
     5641 caaggaaggt acaaggatag taatctgcca gatatttccg ctaagtatcc tgtcgctttt
     5701 caaatcgcaa atgaagcttt tgaaatttac cgtcagaagc tagcagatca ttttcctgag
     5761 gacgaaatta ttcggattgc ttatcatttc attaatgctg aaggtgaaaa tgaagtggaa
     5821 cttgtggagt cgattgataa gaggaaagaa attctcagga atgttgaaga agttttaacg
     5881 gactatgcaa ttcaacgaac taaaaagaat aaccatttct atgatcgctt tatgatccat
     5941 ttgaattatt tcttggatta tttagacaga tctagagatg ataaccaatc acttctggat
     6001 atggaagatc atattaaaca atcctatcca aaagccttcg agattggttc caagatctat
     6061 gatgtgatta cgcaacatac gggtcttgat ttgtataaaa gtgaacgagt ttatctagtt
     6121 ctacatatcc aacgtttatt gtcataaaaa tttatttaaa actatataag gagaattcta
     6181 tcatgaatag agaagaagta acattgttag gttttgaaat cgtagcctat gctggcgatg
     6241 ctcgttcaaa actattggaa gccttgaagg ctgctgaagc tggtgatttt gaaaaagcgg
     6301 acgctctggt agaggaagct ggtagctgta ttgcagaggc tcaccacgcg caaacaagtc
     6361 tattgactaa ggaagcttca ggtgaggact tggcttatag tgtaaccatg atgcatggcc
     6421 aagaccactt aatgacaact atcttgttaa aagatttgat gcatcattta attgaactct
     6481 acaagagagg agttaaataa tgaataaact aattgcattt atcgagaaag gaaagccttt
     6541 ctttgaaaaa ctatctcgta atatctatct tcgtgctatt cgtgatggtt tcattgcagg
     6601 tatgcctgtt attctcttct caagtatctt tatcttgatt gcctttgtac caaactcatg
     6661 gggctttaaa tggtctgatg aagttgtagc ctttctgatg aaaccttata gctattctat
     6721 gggtattctg gctctcttgg tagctggtac aacagctaag tcattgactg actcagtaaa
     6781 ccggagcatg gaaaaaacca atcaaatcaa ctatatgtca acattgttgg cagcaattgt
     6841 tggtttgttg atgttggcag ctgatcctat cgaaagtggt ctagctactg gattcttggg
     6901 gacaaaaggt ttgctttcag ccttccttgc tgccttcgtt actgtagcca tctataaggt
     6961 ttgtgttaag aacaacgtca ctattcgtat gcctgacgaa gttccaccaa atatctcaca
     7021 agtctttaaa gatgtgattc cattcactct ctcagttgtt tcactttatg ctcttgattt
     7081 actagctcgt cattttgttg gtgcaagcgt agctgaatca atcggtaaat tctttgcacc
     7141 actcttctca gcagcagacg gataccttgg tattaccatt atctttggtg cctttgcctt
     7201 cttctggttt gtgggtattc atggtccatc tattgttgaa cctgctatcg cagcaattac
     7261 ctatgcaaat gctgaagtca acttgaacct tctccaacaa ggtatgcacg ctgacaagat
     7321 tcttacttct ggtacacaaa tgtttatcgt taccatgggt ggtactggtg cgacactggt
     7381 tgttccattc atgttcatgt ggttaacaaa atcaaaacgt aaccgtgcaa tcggacgtgc
     7441 ttcagtagtt cctaccttct tcggtgtaaa tgagccaatc ttgtttggtg cacctcttgt
     7501 tttgaatcca atcttcttca ttccatttat ctttgctcca attgcaaacg tatggatctt
     7561 taaattcttt attgaaactc ttggaatgaa ctcattcact gctaatctac catggacaac
     7621 cccagctcca ctaggtctag ttcttggtac taacttccaa gttctatcat tcattcttgc
     7681 tgcccttcta atcgtggttg acgttgtcat ttactatcca ttccttaagg tctatgatga
     7741 acaaattctt gaagaagaac gttcaggtaa gtctaatgat gaattgaaag aaaaagttgc
     7801 tgcaaacttc aacactgcaa aagcggatgc tattcttgaa aaagcaggtg tagaagcagc
     7861 acaaaataca atcactaaag aaacaaatgt cctcgttctt tgtgcaggtg gaggaacaag
     7921 tggtctcctt gcaaatgctc taaacaaggc agcagcagaa tacaatgtcc ctgtgaaagc
     7981 agcagcaggt ggctatggtg ctcaccgtga aatgttgcca gagtttgatt tggttatcct
     8041 tgctcctcaa gttgcttcaa actttgaaga tatgaaggca gaaacagata agctcggtat
     8101 taaacttgct aagacagaag gcgctcaata catcaaatta actcgtgatg gaaaaggtgc
     8161 cctagcattc gtacaagagc aattcgatta aggctaggaa ctgtgaaaca gtctcccatc
     8221 gttacggaaa tcgctatggc gaatttccta atcgccttat taattcgtcg gtaaaaagat
     8281 atcgttttta cctcctcatg tcacaattcg gtgacttggt acaagaagtg agatggagaa
     8341 ggatggctca ctgactcctc tcctctcact tttactttat ttaaatcaag aaataggtga
     8401 aaaaaatgac aaaaacactt ccaaaagact ttatttttgg tggcgcaaca gctgcctatc
     8461 aagcagaagg tgctacacat actgatggta aaggaccagt agcgtgggat aaatatcttg
     8521 aagataacta ctggtacact gcagaaccag ccagtgattt ttacaatcga tatccagttg
     8581 acctcaagct agcagaagag tatggtgtca atggcattcg aatttctatt gcctggtcac
     8641 gtattttccc gactggttat ggtcaagtaa atgctaaagg tgttgagttt tatcataatt
     8701 tatttgcaga gtgtcacaaa cgtcatgttg agccctttgt aactcttcat cactttgaca
     8761 cgccagaagc tctccactca aatggagact tcttaaaccg tgaaaatatc gaacattttg
     8821 tagactacgc tgccttctgt tttgaagaat ttccagaagt aaactattgg acaaccttta
     8881 atgaaattgg accaatcggt gatggtcaat atttggttgg gaaattccct ccaggtatcc
     8941 agtacgacct tgccaaagtc tttcaatcac accacaatat gatggtgtct catgcatgcg
     9001 cggtaaaatt gtacaaagag aaaggctata aaggggaaat tggtgttgtt cacgccctgc
     9061 ctactaaata tcctctagat cctgaaaatc cagcagatgt tcgtgcagca gagttggaag
     9121 atatcatcca caataaattc atcttagacg caacttatct aggtcgctat tcagctgaaa
     9181 ccatggaagg tgtcaaccat atcttatcag tcaatggtgg tagtttggat cttcgtgaag
     9241 aagattttac agcattagaa gctgcaaaag acttgaatga tttcctagga atcaactact
     9301 atatgagtga ctggatggaa gcctttgatg gagaaactga aattatccat aatggtaaag
     9361 gtgaaaaagg aagctctaag tatcaaatca aaggtattgg tcgtcgtgta gctcctgact
     9421 atgtatcacg cacggattgg gattggatta tctaccctca aggtttgtat gaccaaatca
     9481 tgcgtgtgaa gaaagattat cctaactaca agaaaattta tatcactgaa aatggtctcg
     9541 gctataaaga tgagttcgtt aataacactg tttacgatga tggtcgtatt gattacgtga
     9601 aacaacactt ggagatcttg tctgatgcga ttgcagatgg agctaatgta aaaggttact
     9661 tcatttggtc attaatggat gtcttctcat ggtcaaacgg ttatgagaaa cgttatggtc
     9721 tcttctacgt agattttgaa actcaagaac gttatcctaa gaaatcagct cactggtaca
     9781 agaaagtagc ggaaactcag attatagact agtagaatta gtcattagat atagaatttt
     9841 agtgagtcaa aaa
//
LOCUS       DAVKBC010000056         9593 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVKBC010000056 DAVKBC010000000
VERSION     DAVKBC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9593
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.056"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(43..240)
                     /locus_tag="VWX64_001805"
     CDS             complement(43..240)
                     /locus_tag="VWX64_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9191224.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKHLHISPKELKLLGRIVK"
     gene            complement(315..1091)
                     /locus_tag="VWX64_001806"
     CDS             complement(315..1091)
                     /locus_tag="VWX64_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU9191225.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            1213..1959
                     /locus_tag="VWX64_001807"
     CDS             1213..1959
                     /locus_tag="VWX64_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9191226.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYETKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRVIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     CQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAVSDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            1972..2952
                     /locus_tag="VWX64_001808"
     CDS             1972..2952
                     /locus_tag="VWX64_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU9191227.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNVGIVKIEIENFDTNMFKLENYVKEKYSLESLEIIPNEFDDTPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3147..3467
                     /locus_tag="VWX64_001809"
     CDS             3147..3467
                     /locus_tag="VWX64_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9191228.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            3513..3821
                     /locus_tag="VWX64_001810"
     CDS             3513..3821
                     /locus_tag="VWX64_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9191229.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            3838..5136
                     /locus_tag="VWX64_001811"
     CDS             3838..5136
                     /locus_tag="VWX64_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9191230.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            5287..7725
                     /locus_tag="VWX64_001812"
     CDS             5287..7725
                     /locus_tag="VWX64_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU9191231.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            7744..8412
                     /locus_tag="VWX64_001813"
     CDS             7744..8412
                     /locus_tag="VWX64_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU9191232.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            8430..9518
                     /locus_tag="VWX64_001814"
     CDS             8430..9518
                     /locus_tag="VWX64_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU9191233.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT         3166 a         1342 c         1929 g         3156 t
ORIGIN      
        1 tcactatatt agagtaaaat tctctacaaa aagaagaata gcctatttta ctattcttcc
       61 gagtaatttc aattcctttg gggaaatatg gagatgcttt ttaaatactt tggcaaaata
      121 tttatagtct gaaaatccaa cttggtcaga gatagcgctt aaaggggagt tgggagattc
      181 agccatctta tctatagctt gtttcaggcg atattgtaag atatattcat ttagagtcat
      241 ggggaagtct tctttgataa ccttatatag atgcttgtta tctgcaaata gctagagcgt
      301 ttcaaggaaa tgaactagaa ataacaatta atatggtggt tcagaaatac cttttgataa
      361 tcaataagat cttcaggatg aagtgcgttg actccatcca tttcatattt ccgatttaat
      421 aaacgatatt tgttttcacc aaattgatga aaagggagta gttgaacttg gtcgatattt
      481 aatgagttaa atagagtagc gaatttttct gcatcctcta aactattgtt aaaattagga
      541 ataactggga ttcttaaaac gatagtttta ttttgagaaa aagcataatg aatgttttta
      601 ataatcattt gattaaaaac cccagtcact tttttatgtt ttatagaatt ataatgtttt
      661 aggtctgtgt agataaaatc cacatattga attaaatcaa taaatttttc atgatcaaca
      721 aaggcagtag tttcaatggc agtgtgtatg tgatgttctt tagctgattt taagatggct
      781 ttagcaaatt caaactgagc aaatatttca cctcctgata aagttaaacc tccaccggat
      841 tcttcgtaaa attctttgtc ttttaatacc tctgtaataa tttcttctac agtcttttct
      901 tcaccgacta aggtgaattt ctctcgttga gcatctttca ttttttcagg tttcattctt
      961 tgagattcag gattagaaca ccatggacag cgcagaggac atccttttaa aaaaacagtt
     1021 gtacgaatac ccggaccgtc atgaattgaa aagtgttgaa tattaaaaat aattccttta
     1081 gatatttcca taagagttcc tcctcttcat aagtctatcc tatcacaaaa acgaaagaaa
     1141 aacaattacg aacgaaaggt taatttgttg ttttttgctt tttattttgg tagaataaaa
     1201 cggaggtgta aaatgaaaag attggaacaa attattaaat tagtatcaga atatgaaaag
     1261 atcgacgtta atacattatc ggaaaaatta aatgtatcga aagtaacgat tagaaaagat
     1321 ttagataaat tagagtcaaa aggtttatta cacagagagc atggatatgc tgtattaaat
     1381 agtggagatg acttaaatgt acgtttgtca attaattatg aaactaagag aaaaattgtt
     1441 caggaagcag taaaattggt gtcagataat gaaacaataa tgatagaatc tggatcgacc
     1501 tgtgctttac ttgctgagga aatttgcaag caaaaaagaa atgttacgat tgtaacaaat
     1561 tcgtttttta tagcaaattt tgtgagagct tatgattcat gtcgtgttat tgttcttggt
     1621 ggtgagtttc agaaagattc acaggtgact gtaggacctt tattaaaaga aatgatacag
     1681 acttttcatg tgtgtcaagc ttttgttggg acagatggtt acgataaaga gatgggcttt
     1741 accggaaaag atttaatgcg cagtgaggta gttcaatata tttcagcagt gtcggataaa
     1801 gtcattgtcc taactgactc aagtaaattt gataaaagag gtacagtaag aagatttgct
     1861 ttaagtcaag tctatgaagt aataacagac gaaaaacttt ctaaacaaaa tatagctaca
     1921 ttagaaaatg ctgggataat ggttaaggta gtttcgtaag aggttaagtg tatgaatcaa
     1981 gataggaata aactgctttc taaaattgct tatctgtatt atattgaaaa cttaaatcag
     2041 tcacaaatag cagcaaaatt aggaatttat agaacctcta ttagtagaat gttaacagaa
     2101 gcaaggaatg taggaattgt taaaattgaa atagagaatt ttgataccaa tatgtttaag
     2161 ttggaaaatt atgtaaaaga aaaatacagt ttggaaagtt tagaaattat tccaaatgaa
     2221 tttgatgata ctccaacaat tttatctgaa agaatttctc aagttgcagc aggcgtcctt
     2281 aggaatctaa ttgatgataa tatgaaaatt ggcttttctt gggggaaaag tttaagtaat
     2341 ttagtagatt taattcacag taaaagtgtc cgaaatgttc acttctatcc tctagcaggt
     2401 ggtcctagtc acatacacgc taaataccat gtgaatacac tgatttatga aatgtctaga
     2461 aaatttcatg gagagtgtac atttatgaat gcaacgattg tgcaagaaaa taaattgtta
     2521 gcagatggta ttttgcaatc aagatatttt gaaaatttga aaaatagttg gaaagattta
     2581 gatatagctg tagtcggaat tggtgatttt agcaataaag ggaaacatca atggttagac
     2641 atgcttacag aggatgactt taaagaattg accaaagtta aaactgtagg agaaatttgt
     2701 tgtcgatttt ttgattcaaa aggtaaagaa gtctatgaaa acttacagga aagaacgata
     2761 gccatctctt tggaagattt aaaaaatatt cctcaaagtt tagctgttgc ttacggtgat
     2821 acgaaagtat cttcgattct ttctgtcttg cgtgctaatt tagtaaatca tttgattaca
     2881 gataaaaata caattttaaa agttttggaa gaagatggtg atttgacttt tagagagatt
     2941 ctaggtgagt gaaaatgata gactgatcag tttatcgttt tttcttttta gtcgattgca
     3001 catttgtgct tatataaaca aaaatagttt atctgttgtt tttggattga caactttatt
     3061 atgtagttgt attctatagt tacaaaagaa aattttaaaa tttcaaatga aaaaagcttt
     3121 ttacatagtg aaatgaggag gaatttatgg aaattattgt tccagatcaa attatcatgg
     3181 gtttaatttt atatgctggc gatgcgaaac aacatattta taaagcatta gattacataa
     3241 agaacggtac atgtgaacga tgtgaagaag aaatccagtt agctgatgcc gccttattag
     3301 aagctcataa tctacaaaca aaattcttgg cacaggaagc gtctggtaca aagacagaaa
     3361 ttacagctct ctttgttcat tcacaagatc atctcatgac tagtatgacg gagattaatt
     3421 taatcaaaga aattattagt ttgagaaaag aacttcataa aaaataatac tagagtatta
     3481 tcattgttat taacatagag gaggaaaaca taatggtgaa gattggtttg ttttgtgcag
     3541 caggtttttc tactggtatg cttgtaaata atatgaaaat tgcagcgcaa gctagtggag
     3601 ttgaggcaga aatagaggcg ttttctcagt ctaaattagc ggattatgcg ccaaatatag
     3661 atgttgcact attgggtcca caagttgctt atacattaga taaatcaaaa gaaatttgtg
     3721 ataagtgtga tgttccgata gctgttattc cgatgatgga ctatggtatg ttagatggga
     3781 aaaaagtatt agatttggcc ctatctttga ttagtgggta agaaaaggag atttattatg
     3841 tcaaagatgg atgttcagaa aatcattgca ccgatgatga agtttgtgaa tatgcgtggc
     3901 attatagctc taaaagatgg gatgttagca attttgccat tgacagtagt tggtagtttg
     3961 ttcttgatta tgggacaatt gccgttcgaa ggattaaata agagcattgc tagtgttttt
     4021 ggagctaatt ggacagagcc gtttatgcaa gtatattcag gaacttttgc tattatgggt
     4081 ctaatttctt gtttttcaat tgcctattct tatgctaaga atagcggagt agaggcttta
     4141 ccagctggag ttctatctgt atctgcattc tttattttgc taagatcatc ttatatccct
     4201 aaacaaggtg aggcgattgg ggacgctatt agtaaagttt ggtttggagg ccaaggaatt
     4261 atcggtgcta tcattatagg tttggtagta ggaagtattt ataccttctt tataaagaga
     4321 aaaattgtta ttaagatgcc agaacaagtt ccacaagcta ttgccaaaca gtttgaagca
     4381 atgattccag catttgtaat tttcttatct tctatgattg tatatatttt agcgaagtca
     4441 ttgactaatg gcggaacatt catagaaatg atttattctg ctattcaagt tccgttgcaa
     4501 ggtttaactg gatctttgta tggtgctatt ggaattgcat tctttatatc atttttgtgg
     4561 tggtttggtg ttcatgggca atcggtagta aatggagtag tgacagctct gcttttatct
     4621 aatcttgatg ctaataaagc tatgttagcc tctggtaatc tatcattaga aaatggtgca
     4681 catattgtta ctcaacaatt tttagattca tttttaattc tatcaggttc agggattacg
     4741 tttggtcttg tagttgccat gctttttgca gcaaaatcaa aacaatacca agccttagga
     4801 aaagttgcag cttttccagc aatatttaac gtaaatgagc cagttgtatt tggatttccg
     4861 attgtcatga atccagttat gtttgtacct ttcattcttg ttcctgtact tgcagctgtg
     4921 atagtatatg gagctattgc aacaggtttc atgcaaccat tctcaggggt aacattgcct
     4981 tggagtacac cagctattct atcaggattt ttggtgggtg gatggcaagg tgttgtgact
     5041 cagttattag tattggtgat atctacagtg gtttactttc cattctttaa gatacaagat
     5101 cgtttagctt accaaaatga aatcaaacaa tcttagaggt atttgtgtgt tactgttaaa
     5161 ctcacacatt tgtgctaaaa attagagagt taaaattttt ctagttaaaa gcttgaaaat
     5221 ttctataaaa atcggtatta tattttcgaa agaaataaaa atattttcga aagaaaggtg
     5281 cttacgatgg taaatacaga agtagcaaga acaacaatca agacagaata ttttggcagc
     5341 cttactgaaa ggatgaacaa atatcgagaa gatgttttaa ataaaaaacc ttatattgat
     5401 gctgagagag cagttctagc aacacgcgcc tatgaacgat acaaggaaca acctaatgtc
     5461 ctaaaacgtg catatatgct gaaagaaatt ttggaaaata tgtctatcta tattgaagaa
     5521 gaatctatga ttgcgggaaa tcaagcttct tccaataaag atgctcctat ttttccggaa
     5581 tatacgctag aatttgttct caatgagttg gatctttttg aaaagcgtga tggagatgtt
     5641 ttctatatta cagaagaaac aaaagaacaa cttagaagta ttgctccgtt ttgggaaaat
     5701 aataatttac gtgctagagc tggtgcctta ttacctgaag aagtgtctgt ttatatggaa
     5761 acaggattct tcggtatgga aggtaagatg aattctggag atgctcactt agcagttaac
     5821 tatcagaaac ttttgcaatt tggtttaaga ggttttgaag agcgggctcg taaagcaaaa
     5881 gtagctctag atttaacaga tccagcaagt attgataaat atcattttta cgactctata
     5941 tttatcgtaa tcgatgctat taaagtatat gcaaagcgct ttgttgctct tgctaaaagt
     6001 ttagccgaaa atgcaaatcc taaacgtaag aaagaattac ttgagattgc agatatttgc
     6061 tctagagtcc catatgaacc ggcaactact tttgcagaag ctattcaatc agtttggttt
     6121 attcaatgta ttttacaaat tgaatctaat ggccactctc tttcatatgg ccgttttgat
     6181 caatatatgt atccatatat gaaggctgat ttagaaagtg gtaaagaaac agaagatagc
     6241 attgttgaac gtctgacaaa tctttggatt aagacaatta caattaataa ggttcgcagt
     6301 caatcacata cattttcttc agcaggaagt cctttatatc aaaatgttac aattggtgga
     6361 cagactcgag ataagaagga tgctgttaac ccattatctt atttggtctt aaaatcagtt
     6421 gcacaaaccc atctaccgca acctaatcta actgtacgtt accatgcagg tttagatgct
     6481 cgtttcatga atgagtgtat tgaagtgatg aaacttggtt ttggtatgcc tgcatttaat
     6541 aatgatgaga ttattattcc ttcttttatt gcaaaaggag tattggaaga tgatgcttat
     6601 gattacagtg ccattggatg tgttgaaacg gcagttccag ggaaatgggg ctatcgttgc
     6661 acaggtatga gttatatgaa cttccctaag gttctactta tcacgatgaa tgatggaatt
     6721 gatccggctt cgggtaaacg gtttgcacca agctttggtc attttaagga tatgaagaac
     6781 ttttctgaat tagaaaatgc ttgggataaa acactaagat atttgacacg aatgagtgtt
     6841 attgttgaaa attctattga tttatcattg gaacgagaag ttcctgatat tctatgttca
     6901 gcattgactg atgattgtat tggtcgtgga aaacacctta aagaaggtgg agcagtatat
     6961 gattatatat caggattgca agttggaatt gcaaatttgt cggattcatt agctgcaatt
     7021 aaaaaattgg tgtttgagga agaacgtata agcccaagtc agctttggca tgcactggaa
     7081 acagattatg ccggagaaga aggtaaggtc attcaagaaa tgttgattca tgatgcacct
     7141 aagtatggta atgatgatga ttatgctgac aaattggtta ctgctgctta tgacatttat
     7201 gttgatgaaa ttgctaaata tcctaataca cgttatggaa gaggtccaat tggaggaatt
     7261 cgttattcag gaacatcttc tatctcagcc aacgtagggc agggacgtgg aacattagca
     7321 actccagatg gacgcaacgc gggtacaccg ttagcagagg gttgttcacc atcacataat
     7381 atggatcaac acggccctac atctgtttta aaatctgttt caaaattacc aacagatgaa
     7441 atcgtaggtg gggttctctt aaatcagaaa gtaaatcctc aaacgttagc caaagaagaa
     7501 gataaattaa aactaattgc tttgttacga acattcttta atcgtttaca tgggtaccat
     7561 attcaataca atgttgtttc cagagagacg ctgattgacg ctcagaaaca tcctgaaaaa
     7621 cacagagact taattgttcg tgttgcagga tactctgcat tcttcaatgt tctttctaag
     7681 gcaacccaag atgacattat aggacgtact gagcatactt tgtaaaataa agaggttctt
     7741 tttatggaat ttatgcttga cacattaaat ttagatgaga ttaaaaagtg gtctgaaatt
     7801 ttgccgctag ctggggtaac ttcaaatccc actattgcaa aaagagaggg ttctattaat
     7861 ttttttgaac gaatcaaaga tgtaagagaa ttgattggct ctacaccctc tattcatgtt
     7921 caggtgattt ctcaagattt tgaaggcatc ttaaaggatg ctcataaaat tcgaagacaa
     7981 gcaggagatg atatatttat caaagtacct gttactccag ctggattacg tgcaataaag
     8041 gcgctaaaaa aagagggcta ccatatcact gcaacagcta tttatacagt tattcaggga
     8101 ttattagcta tcgaagcagg agcggattac ctagctccat attataatag aatggaaaat
     8161 ctgaacattg attcaaattc tgtcattcgt caattagctc ttgctattga tagacagaac
     8221 tctcctagta agattttagc tgcatccttt aaaaatgtag cacaagtaaa taatgcttta
     8281 gctgcaggtg cgcatgctgt tacagcagga gcagatgttt ttgaatcagc tttcgccatg
     8341 ccatctatcc aaaaggcggt tgatgatttt tctgacgatt ggtttgttac tcaaaatagt
     8401 cgttccattt agatagagag gaaatacata tgagaatttt tgctagtcct tctagatata
     8461 ttcaggggga aaatgccttg tttgaaaatg ccaaatcaat tttggatttg ggaaattacc
     8521 cgattctatt atgcgatcag ttggtttatg atattgttgg aaaacgattt gaagattatc
     8581 tacataggta tggtttccat attgttctgg cgctatttaa tggtgaagct tctgacaatg
     8641 aaatcaatcg agttgttgcc ttggctgaga aagaaaattg tgatagtatt atcggtcttg
     8701 gtgggggaaa gacgattgat agcgcaaaag ctattgcaga tttgattgaa aagcctgtta
     8761 ttattgctcc aacaattgca tcgaccgacg cacctgtatc tgctttatct gttatttata
     8821 cagatgaagg tgcatttgat cattatctat tttattctaa aaatccagat ttagttttgg
     8881 ttgatacaaa agttatttca caagccccta agcgtttatt agcgtctggt attgcagatg
     8941 gtttagcaac ttgggttgag gcgcgtgcgg ttatgcaggc aaatggaaaa actatgttgg
     9001 gacaacagca aacattggct ggagttgcaa ttgcgaagaa atgtgaagaa acgctgtttg
     9061 cagatggttt acaggctatg gcagcttgtg aagctaaagt ggtgacacca gcattagaaa
     9121 atattgttga agctaatact ttattgagtg gtctaggttt tgaaagtgga ggattagctg
     9181 cggcgcatgc aattcataat ggttttactg cattgacagg tgacattcat catttaacac
     9241 atggtgaaaa agtagcttat ggaactttag tacaactatt attggaaaat agacctaaag
     9301 aagaacttga taagtatatt gagttttaca aaaaaattgg tatgccaaca actctaaaag
     9361 aaatgcattt ggatcaagtt ggatatgatg atttaataaa agttggtaaa caagcaacta
     9421 tggagggtga gacaattcat cagatgccgt ttaagatttc gccttcagat gttgctcaag
     9481 ctattatcgc tgtagatgcc tatgtaaatt caaaataaac aataaggact actgttttcc
     9541 aaatggtagt cttttattga tccctgtatt gaattctata gaagattgaa ata
//
LOCUS       DAVKBC010000057         8953 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVKBC010000057 DAVKBC010000000
VERSION     DAVKBC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.057"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(321..1169)
                     /gene="dprA"
                     /locus_tag="VWX64_001815"
     CDS             complement(321..1169)
                     /gene="dprA"
                     /locus_tag="VWX64_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU9191234.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDIFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1255..1944)
                     /locus_tag="VWX64_001816"
     CDS             complement(1255..1944)
                     /locus_tag="VWX64_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU9191235.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1956..2834)
                     /locus_tag="VWX64_001817"
     CDS             complement(1956..2834)
                     /locus_tag="VWX64_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU9191236.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2824..3693)
                     /gene="licA"
                     /locus_tag="VWX64_001818"
     CDS             complement(2824..3693)
                     /gene="licA"
                     /locus_tag="VWX64_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU9191237.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            complement(3710..4732)
                     /locus_tag="VWX64_001819"
     CDS             complement(3710..4732)
                     /locus_tag="VWX64_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9191238.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4737..5444)
                     /locus_tag="VWX64_001820"
     CDS             complement(4737..5444)
                     /locus_tag="VWX64_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU9191239.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5780..7267
                     /gene="tacF"
                     /locus_tag="VWX64_001821"
     CDS             5780..7267
                     /gene="tacF"
                     /locus_tag="VWX64_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU9191240.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7277..8080
                     /locus_tag="VWX64_001822"
     CDS             7277..8080
                     /locus_tag="VWX64_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9191241.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8082..8891
                     /locus_tag="VWX64_001823"
     CDS             8082..8891
                     /locus_tag="VWX64_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9191242.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2808 a         1804 c         1516 g         2825 t
ORIGIN      
        1 tttcccttat actcaatgaa aatcaaagcg caaactagga agctagccac aggttgctca
       61 aagcactgct ttgaggttgt agataagact gacgaagtca gctcaaaata ctgttttgag
      121 gttgcagatg gaagctgacg tagtttgaag agattttcga agagtattat atgaaaaaat
      181 cctctactct actaatccac ttagaaaaaa cgcatattat caagtgttaa aaacttgcta
      241 atatgcgttt tattatggaa atgttgggtt cattttctct taaaattgat tttttcttag
      301 aattctagct taggtcattt ttaaaattca aattccgcaa gaacatcttg cccactggtg
      361 accaattttg ctccttcttg aatcaaatga tggcaaccgt ctgatagtcc atctaaaatg
      421 ctaccaggaa tagcaaagat atcgcgtcct tcttccattg ctcgctcaca ggtaatgaga
      481 ctacctgaac gcatcttagc ctctgctaca atcacaccac gacaaagtcc agcaatgatg
      541 cgattacggg caggaaaatg aaatttcaga ggttgttcgc caggtccata ttcacttaga
      601 gccagatggt cattgccgat gtagtcttgc aagcgtttgt tggctttagg ataaaacaca
      661 tccagtcctg ttccaatcac tgcaatggtt tttccgccat tctgaagagc tgccatatga
      721 gctgctgtgt caatgccctt ggccagacca ctgacaataa ccagttcatt ttccaagcct
      781 tgaatgactt tttcaactga cttagctccc tgtttgctac aagcacgact gcccacgacc
      841 gctaccttcg ggaatttcag gaggtcaaga tttcccttgt aaaataaaag tacaggcgca
      901 tcatatattt cactcaaatc ccaaggataa cagtcatcta aaatagagaa agatggaaat
      961 ttttgaaact ctttcgacaa atgcgcatcg tctatctgaa aataacgttc cataaaaacg
     1021 gctggattac ggcaacctga gatatctgca atatcaccca acaaaagctc ctgatcaaca
     1081 ttttcaccgt attctagcac tttcaaaatc tgttgattgg tcaaacctga tttttttaac
     1141 ttatagattt catagtttgt aattttcata aataactcca tttctttttc tactcatcta
     1201 tctattcgta aaaaatcaaa aaacatccga ctattttgtc agatgttgga atctttaatt
     1261 ttcgttttta agaatttctt ctaatttacg atagtcttgg acactatcga tctcataaat
     1321 gctattgcct tctaattctt caacatagac atctagctct ttgatattat ccttaaccat
     1381 attgtcccag tagagatcaa caaattcacc acttgcataa gccttgtcga taaagctgac
     1441 aatcttttct gcagttggag catcccagaa ggatacacca ctaaggatgc gacctgcctt
     1501 gctatcaaca ataatgtctt gaaccttgta gtcatctcca tagaccaaga accattcgtt
     1561 ggtacaatct tcacgataaa cactaaaata agtcgaacgt gtcaaatcat tgcggaacat
     1621 atttttaaag agataattgt cagcatcaat aacatagctg ttggccaatt cttcttttac
     1681 aagatagaga gagtaaaagt tattgtagtc agcgtattta tcattgaaaa cgaggcgaac
     1741 accgtatttt tcttttaaat aatcgaattg ttctttaaga taaccaacga tgatgatgat
     1801 gtcattgatt cctttttctt tgagaaactc aatttggtat tcaatcaaag gtttttgatt
     1861 aacctgaacc aaggctttag gggtattttc agtcatagga cgcaagcgag ttcccaatcc
     1921 cgctgctaag ataatggctt tcacacgaat ctcctttatt ctttaataat aatataaact
     1981 ccagcaatga cgacaagtga cgtcataatg gtcagcatat ctaatgatgt tcccaagaaa
     2041 agagctgcga acaagacagt ccatactaca tagctcacgt tcaagcctgt agccttggct
     2101 ggttgcaagc gattgatagc gatataataa gccaaatagg aaatcatatc aaaggctaca
     2161 aagacaatca tgagacctag caattgtcca ttggctactg caacaaatga ctgatgagag
     2221 aagagcacaa tcacaagata ggacaagaac gaagttactt gacggattaa gagggcttcg
     2281 atttcactca attcactttc catggcaaaa gagctaagaa cactctcact tccccatgca
     2341 atagcacaaa ccaaagcaca aagaatccca atgtagaaag aattaacctg ttcaacctta
     2401 taggtctggg caataatccc tccaataatc aagacaatcc caaatacagt atttttcgaa
     2461 atcttgtgct tcaaaaagaa gaaagccaat agaactgaaa tcgcagggta aatagccgat
     2521 acagatgaag ctaaagaact tccaatatac ttaactgcat aaagattggc ctgcataccg
     2581 atagggcctg ctagcaaggc tcctatgata acactgacat tgcgaatatt taagaaaatt
     2641 gagaggcgaa ctttcccttc ttttaccaag agaaaagcta gtaagataaa gatgctcaaa
     2701 aaatcatgag ttgcagccac cacaaagggt gacaaatctg taaaaatcga aaagatataa
     2761 gcactaaccg ttagacccaa gccccagaaa atacctgaga gaaggccaaa aggaactccg
     2821 tttttacttt tcatctgaac ctccataaga agccaaacct ttaatagctc tttggtaacg
     2881 attcacacca tagtcaccaa aatcttcacc ttgctcttcc ttatagacag tccatagact
     2941 ccaaatagta tcttgtaaaa ttttataaat agcaatcttt tcatgagaaa ccggtgtttg
     3001 gtcactctca tagtgagata agaaagtttc ttcctcttgg gaagtgaatt cagactctaa
     3061 aaagagggca gccaaatccc acattggatc attcattgat gaatattccc agtcaatcaa
     3121 ataaagtcgt ccttgaggtg attcgataaa gttttcaggc accaaatcga tatgacaaga
     3181 ttttctgtca acacctaagt cagccagtct tttctctaag gagaagactg catttctaac
     3241 agattcatag ttggcataag gaatttgttc ttcaatcaag gattcgtatt ttttgatttc
     3301 ttcaaaagga gcaaattctc ctcttaattc cttagcagac gtatgaatag tttgtaatat
     3361 tggagtaatt ttgtcgaact tggtcttgat tgacgttgaa tcaagcgtaa tcgcagattc
     3421 gatatactca tttactttga taccagcttc aatatcaaaa agataatttt ttacatctaa
     3481 gcctaaatcc tttagtagtt caagattgta cttttcatct tgtcgattga taagcttttc
     3541 tgtcccttta ccaaagaatt taacaatgta ttgcttattt gttgttttgg ccaaatagtt
     3601 ttgattggtc attccaccca gttgttcaac actgaggact tcctcttctt gactaagtaa
     3661 ggaagaaatt ttttctttaa tgattttctc cacaattaac ctccagtact tatacttccc
     3721 acttaaacac tgttttaaag gctgtgttta aatcggttgc aaagacacga tgaatatctt
     3781 taatttctct tacaggttct tctagataaa ggatattttt aagacgattg gcaaatttct
     3841 tgacttccat catttggata gcattttcaa aatcaatgcg accagaacga gatgacccaa
     3901 ccaaaatcaa gcccttttct aaggcatcgc gagtattgag attgacttta tattcgctaa
     3961 ctcccatcat gagaatcgtt ccctgaggac gaatgtagcg aatcaagtca ttaatagctg
     4021 gtccagtacc atcaccacca caacattcaa aagcatggtc aaaggccaaa tcttcaggaa
     4081 tattatccgt aatatagcat tctttggcaa atgagaagag ttccaacttt tcccaatgac
     4141 gaccaataac cacaatctct gcttctggca aagtatagtt gataatattg gcaaccacaa
     4201 aagctaaact cccatctcca ataacggcga tccgctcccg cttgctatga gcaagagtca
     4261 atagacgatt catagcgtgc atgcccacac tgacaaactc tgtaatggct gcaaccgtat
     4321 cttcaatagc atcataagcc accacacgat ctttagggag agaaacaaac tctctcataa
     4381 agccatcaaa tccactagac aagaaatggg tccctgtcat gtagttttca tagaattctt
     4441 catcactctg cataggagac tgattgggaa tcatgacaac tttttgacca acctcgtagg
     4501 ttccggtcgg gtcagaaatg acggttccac atgactcgtg aatcattgcc attggaagct
     4561 ttttattcaa aatcttggga tcacgttttc cctgatagta acgctgatcc gcatgacaga
     4621 cagccatgta gttgggacgg ataaggatat gattctcttg gtcaatagcc tcttcctgat
     4681 atttgacatt gataaactta ggcttagtta gttgataaat ttgattaatc attttactag
     4741 tctttctcaa tcatactttt tgcaatcttc aaatctgtta cggttgtaat cttcagattt
     4801 gagtattcac ctttggccaa ggccacatct tttcctttga tcacaaagat tttacatgca
     4861 tctgtcaaga tttccttctc ttcatcagaa agagatccat aaaggtccat gaagtccttg
     4921 caacggaatg tttgaggtgt ttgtccttga taaaggtgag cacgatttgg aatatctgta
     4981 ataaattgac cattggtact ttcaacgata gtatcaaccg cttctaccac tgtgtccact
     5041 gcgtcatgat tttgggcaag ttggatattg tcctgaatca tgcgaagtgt aataaatgga
     5101 cgaacagaat cgtgggtaac aacgatatcc tctggagtaa gcggacgata agcatcaatg
     5161 gcttcaatga ttttcttaat acttgtattg cggtcagcac caccctttgt aatgatgata
     5221 cgttccttat aaagaggaag atatttatct acaagatctt ctgcatgaga aacccagtct
     5281 ccatgaacac caactacaat tttttcaata cttggctcca agacaaattt ttcaattgta
     5341 tgaatcaaaa taggtcgatc acctagctct aaaaattgtt ttggcaagtt actgatcccc
     5401 atgcgtgtgc cagttccacc ggcaagaatt cctgcataaa tcatctattt tctcctttgt
     5461 cttactaaaa aaacttattc tctctattat accacaatct agtcctatca taaaagaaat
     5521 actggtcctc cccttctaga ataggagaat tatgcagttc tattattcaa agaaactagt
     5581 ccatttctag taatgactag gaattctgta gcaattacta ataaatggct gcgaaatttt
     5641 agagtccttc agaataatat actttcctta aagaaaactt aaaacttaag atttgaaact
     5701 tcaaagtgat tacttgactt actgcccttc atttcttatt agctaacttt atgatataat
     5761 gaaaaacgag gtaaattgaa tgaaaagtat aaaattaaat gctctatctt acatgggaat
     5821 tcgtgtcttg aatattattt ttcccatcct aactggaacc tatgtcgcgc gtgtcttgga
     5881 ccgaactgac tatggttact tcaactcagt cgacactatt ttgtcatttt tcttgccctt
     5941 tgcaacttat ggtgtctata actacggttt aagggctatc agtaatgtca aggataacaa
     6001 aaaagatctt aacagaacct tttctagtct tttttatttg tgcatcgctt gtacgatttt
     6061 gaccactgct gtctatatcc tagcctatcc tctcttcttt actgataatc caatcgtcaa
     6121 aaaggtctac cttgttatgg ggattcaact cattgcccag attttttcaa tcgaatgggt
     6181 caatgaagct ctggaaaatt acagttttct cttttacaaa actgccttca tccgtatcct
     6241 gatgctggtc tctattttct tatttgttaa aaatgaacac gatattgttg tctatacact
     6301 tgtgatgagt ttatcgacgc tgattaacta cctgattagt tatttttgga ttaaaagaga
     6361 catcaaactt gttaagattc acctaagtga ttttaaacca ctctttctcc ctctgacagc
     6421 catgttagtc tttgccaatg ccaatatgct cttcactttt ttagatcgcc tcttcctcgt
     6481 taaaacaggg attgatgtca acgttagtta ctataccata gctcagcgaa ttgtgaccgt
     6541 tatagctggg gttgtaacag gtgcaattgg agtgagtgtg cctcgtctca gttactatct
     6601 ggggaaagga gacaaagaag cctatgtttc tctggttaat agaggtagtc gaatctttaa
     6661 cttctttatc attccactga gttttggact catggtttta ggaccaaatg ccatcctact
     6721 ttacggtagt gaaaaatata tcggaggcgg catcttgacc tctctcttcg cttttcgtac
     6781 gattatcctg gccttagata ccattcttgg ttcccaaatt ctctttacca atggctatga
     6841 aaaacgtatc acagtctata cagtctttgc tgggctactc aatttgggct tgaatagtct
     6901 cctctttttc aaccatatcg tagctcccga atactactta ctgacaacta tgttatcaga
     6961 ggcttctcta cttgttttct atatcatttt catccataga aaacaactca tccacttggg
     7021 acatatcttt agctatactg ttcgatactc tctcttttca ctttcctttg tagcaattta
     7081 tttcctgatt aatttcgtgt atcctgtgga tatggtcatt aatttgccat ttttgattaa
     7141 tactggtttg attgtcttgt tatcagctat ctcttatatt agtctacttg tcttcacaaa
     7201 agatagcatt ttctatgaat ttttaaacca tgtcctagcc ttaaaaaata aattcaaaaa
     7261 atcataggag tttaaaatga aacaactaac cattgaagat gccaaacaaa ttgaattaga
     7321 aattttggat tatattgata ctctctgtaa aaagcacaat atcaactata ttattaacta
     7381 cggtactctg attggggcgg ttcgacatga gggctttatc ccttgggacg acgatattga
     7441 tctgtccatg cctagagaag actaccaacg atttattaac atttttcaaa aggaaaaaag
     7501 caagtataag ctcctatcct tagaaactga taagaactac tttaacaact ttatcaagat
     7561 aaccgacagt acgactaaaa ttattgatac tcgaaataca aaaacctatg agtctggtat
     7621 ctttatcgat attttcccta tagatcgctt tgatgatcct aaggtcattg atacttgtta
     7681 taaactggaa agcttcaaac tgctgtcttt cagtaaacat aaaaatattg tctataagga
     7741 tagcctttta aaagattgga tacgaacagc cttttggttg ctccttcgac cggtttctcc
     7801 tcgttatttt gcaaataaaa tcgagaaaga aattcaaaaa tatagtcgtg aaaatgggca
     7861 gtatatggct tttattcctt caaaatttaa ggaaaaggaa gtcttcccaa gtggtacctt
     7921 tgataaaaca atcgatttac cctttgagaa tttaagcctt cctgcacctg aaaaatttga
     7981 tactattttg acacaatttt atggagatta tatgacccta ccaccagaag aaaaacgctt
     8041 ctacagtcat gaatttcacg cttataaatt ggaggattag gatgcaatat ttagaaaaaa
     8101 aagaaattaa agaaattcaa ctagccctgc tggactatat tgatgagact tgtaagaaac
     8161 atgatattcc ttattttctc agttatggaa ccatgcttgg agccatccgc cacaaaggta
     8221 tgattccttg ggatgatgat attgatattt ccctttatcg tgaggattat gagcgtttac
     8281 tgaagattat tgaagaagaa aatcaccctc gctacaaggt tctttcctac gatacatctt
     8341 cttggtactt ccataatttc gcatcgattt tggacacttc tactgttata gaagaccatg
     8401 ttaagtacaa gcgtcatgat accagccttt tcatcgatgt cttcccaatt gatcgattta
     8461 cagacttgag cattgtcgac aagagctata agtatgtggc tcttcgtcaa ctagcttata
     8521 tcaaaaaatc acgagcagtt cacggtgata gcaaactaaa agattttctt agattatgta
     8581 gctggtacgc tctccgattt gtcaatcctc gctactttta caagaaaatt gatcaactag
     8641 tcaaaaatgc tgtaaccaac actcctcaat atgaaggagg agttgggatc ggtaaggaag
     8701 ggatgaaaga aatcttccca gttgatacct ttaaagaact gattttaact gagtttgagg
     8761 gccgtatgtt gcctgttccc aaaaaatatg accaattttt aacccagatg tatggcgatt
     8821 atatgacacc accatcaaaa gaaatgcaag agtggtatag tcatagcatt aaagcttatc
     8881 gcaaaaactg attgaggggg attatacaga ctactaagat agaggttatt caaaaacata
     8941 attttagtag aaa
//
LOCUS       DAVKBC010000058         8746 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVKBC010000058 DAVKBC010000000
VERSION     DAVKBC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8746
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.058"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            10..1011
                     /locus_tag="VWX64_001824"
     CDS             10..1011
                     /locus_tag="VWX64_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9191243.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1610..1690
                     /locus_tag="VWX64_001825"
                     /pseudo
     CDS             1610..1690
                     /locus_tag="VWX64_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            2419..3780
                     /gene="trpE"
                     /locus_tag="VWX64_001826"
     CDS             2419..3780
                     /gene="trpE"
                     /locus_tag="VWX64_001826"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU9191244.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3777..4343
                     /locus_tag="VWX64_001827"
     CDS             3777..4343
                     /locus_tag="VWX64_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU9191245.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            4354..5358
                     /gene="trpD"
                     /locus_tag="VWX64_001828"
     CDS             4354..5358
                     /gene="trpD"
                     /locus_tag="VWX64_001828"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU9191246.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5355..6122
                     /gene="trpC"
                     /locus_tag="VWX64_001829"
     CDS             5355..6122
                     /gene="trpC"
                     /locus_tag="VWX64_001829"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU9191247.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            6109..6708
                     /locus_tag="VWX64_001830"
     CDS             6109..6708
                     /locus_tag="VWX64_001830"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU9191248.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            6686..7909
                     /gene="trpB"
                     /locus_tag="VWX64_001831"
     CDS             6686..7909
                     /gene="trpB"
                     /locus_tag="VWX64_001831"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU9191249.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7902..8678
                     /locus_tag="VWX64_001832"
     CDS             7902..8678
                     /locus_tag="VWX64_001832"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU9191250.1"
                     /translation="MPKTLTEKLNAIKVTGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(8650..>8746)
                     /locus_tag="VWX64_001833"
     CDS             complement(8650..>8746)
                     /locus_tag="VWX64_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU9191251.1"
                     /translation="FILQKKKERLPFVPFLLLATCLIIFGKLLLV"
BASE COUNT         2595 a         1632 c         2113 g         2406 t
ORIGIN      
        1 aggactgaaa tgaaaaatat aaatgggaaa aaggtaacta tttatgatat tgcacgttta
       61 tcaggttttt ctccaaaaac agtttcacga gttattaatg gtggagtaaa tgttaaagaa
      121 gaaacttatc aagcgattca aaaagttata gaggaattgt cgtatattcc aaatgcgtat
      181 gcaaaaaatt taactaaaaa agaagctata aatatattga tttctgtaaa aaaaatcgac
      241 tcttttcctt taatttggtt tcatacgctg ttagataaag tgttacggac gtgtaaagaa
      301 tttggtgtta atgctatagt tgagtacttt ggagaggagg atacaattag taattcaatt
      361 atatcaagca caggtagcct agtagatggt gttattgttt tttatgaaag tgtagatgat
      421 atcagaattc agtatttaaa gaagaaccat atgccttttc ttgttttcgg tgaatctcaa
      481 acgtctggag tagtctatgt atctaataat aattttcaag ctacttatga tatgatgaaa
      541 gctgtaactg aagaaaaatt taaaaatatg tggttgctta tgggaggaga atcccatgtt
      601 aataaggatc gtgaaagagg tgtgcgttct tttctgaatg ataaaaatta ctttatggat
      661 ttaaaagtca tttatggctt atctacaatt gattcagttt attcttatgc aatgcagcac
      721 ttgactaccc aaaattatcc ggacattatt tttgtttcag gagatgaaaa ggttcagggc
      781 ttgattcgtg cgtgctatga gaaaggaatt cttattccag atgatatttc tatcattgga
      841 tttgataata ttcctatttc tcagtattat actccagctt tgtctacaat tgctcccaat
      901 tatgttaaat tggctaaaga aatgatagaa ggtgttttag caattattaa aggggaaagt
      961 gtcacatctg ttgaagtttc tcctaaattt gttaggagac agagtttcta gtattgttta
     1021 attcttgaaa atcctagtgg aaaagatgga gtgttctaaa ataagttctg tttagcctcc
     1081 attcagtttc tattgagttg gatccaattt ctaacaagtg ggacatgttc atgttcgatc
     1141 taaggaagat atggtcacat tcgaatgata tcaaaaaaat cgtaaaaaag tcttgacaaa
     1201 gaaaaaacaa agtattaaaa taagttcaac aaatcagaaa agtaactatt tttgatcttc
     1261 agggagcctg tggtgattgt gaataggtgg ttggaagtag tgaaagtggg ctgattttga
     1321 aaatgaattt gaaacaatga aaattcggtg cgcacacctt acagtgcagc ttgttgttaa
     1381 acaaggcaga gatgtaaagg gatagtccct ttataattga ggtggcaccg cgttaccaac
     1441 gccctcacac ggaagtatat tctgtgtgtg ggcttttttc tatccgtcgt ttggtttatc
     1501 ttttattagg gccttaagtc gctttgatga acttgagttc tatctacagc tccttgcctc
     1561 ctactaaaag taaacaaaaa ggctggacta atacgaaaaa agctagtaat actcaatgaa
     1621 aatcaaagag caaactagga aactagccgc aggctgctca aaacactgtt ttgaggttgt
     1681 ggatagaact gacgaagtca gctcaaaata ctgttttgag gttgtggata gaactgacga
     1741 agtcagctca aaatactgtt ttgaggttgt ggatagaact gacgaagtca gctcaaaaca
     1801 ctgttttgag gttgtggata gaactgacga agtcagctca aaacactgtt ttgaggttgc
     1861 agatagaact gacgaagtca gctcaaaaca ctgttttgag gttgcagata gaactgacga
     1921 agtcagctca aaacactgtt ttgaggttgc agatagaact gacgaagtca gtaaccatac
     1981 ctacgataag gcgacgttga cgcggtttga agagattttc gaagagtata aaggtgtacc
     2041 gagatgaaca tctcttcatc aatgtctctg gtcgtggagg caaggaccta gctgcgattg
     2101 cagattacta gaagctaaaa aataatagat ggaaaaatta cagttctttc tctcacagag
     2161 agcttgtggt tgctgaaaac aagcagagaa agctgtaaag ttgggttcat ctgaaacgag
     2221 agaagaaaac atcattctca agggagtgcc ctttatcgca cagcctgtta caggagatat
     2281 ctgagacagg aatgagagat aggagaaatc ctataattga ggtggcaccg cgaatttcgt
     2341 cctcacgcaa gttattttgc gtggggattt ttcatacagt caccacggac tagaagtaga
     2401 actgaaaggg aaattacaat ggaacgaatc attcatggag atgtcttatc accaatcttg
     2461 gcttatatgc gcttaaaggg gcaacataag gttattttag agagtattcc gagagacaag
     2521 gaaacagctc gtttttctat cctagcctat aatccagttt ttgagattaa gtttgaaaat
     2581 ggagttctct atcaaaatgg tcaagtgatt gatcgggatc ccttggattt cctttatgaa
     2641 gtgattcata agagtcagca ccactcagag ctaccttttg gtggtggagc cattggtttt
     2701 gtgggttacg atatgatttc gctttatgaa gaaattggtc aaatccctga ggatacaatt
     2761 gggacgccag acatgcattt ctttgtctat gagagctata tggtctttga ccacaagaag
     2821 gagaagatac atgtcataga ggatgcactt tatagtgagc gcagtcaaga ggccttggaa
     2881 aaatccttga accaagtgct tgaggaatta cgcattcctg ctccaaatga atttgaagat
     2941 ttggatctat ctccgttaga cttcaaaccg catatcgctc cacataagtt tgagggaatg
     3001 gtagaaacag ctcgtgactt gattcgtaac ggagatatgt tccaatgtgt actcagccag
     3061 cgtttctcag cagaagttac tggaaatcca tttgacttct acagaaatct ccgcgtgact
     3121 aatccttcta attaccttta tttctatgat tttggggatt atcaaatcat cggagctagt
     3181 ccagaaagtt tagtttctgt caaaaatggc atcgtgacaa ccaatccgat tgcagggacg
     3241 cgaccaagag gggctacgga tgaagaagac aagaccttgg cgactgacct cctctctgat
     3301 gagaaggaaa cagcagaaca tcgaatgttg gtagacttgg ggcgtaacga tattggccgc
     3361 atctctgaaa cggccagtgt ccaagttact aagtatatga aggtggagct cttccgctac
     3421 gtcatgcatt tgaccagcgt ggtcaagggg cgtttgcttc cagaactcac ggccatggat
     3481 gccttgaaag ctacacttcc tgctggaacc gtttctggag caccaaagat tcgggcgatg
     3541 agacgcatct atgaactgga aacggaaaaa cggggcgtat atgcaggagc aatcggctac
     3601 ttgtctgcga cgggtgatat ggatttggcc attgccatcc gaaccatgat tctcaaaaat
     3661 caaagagcct atgtgcaggc tggggcaggg attgtctacg actctatcgc ccaaaacgaa
     3721 taccaagaaa ccattaacaa agcaaaatct atgactagaa ttggagaact aagaccatga
     3781 ttttattgat tgacaactat gattctttta cctataactt ggcccaatac attgggaatt
     3841 ttgcagaagt tcaggttctg agaaatgatg attccaagct gtatgaagaa gctgaaaaag
     3901 cagatggtct ggtcttttct cctggtcctg gttggccagt tgatgctgga aagatggaag
     3961 acatgattcg tgattttgca ggcaagaagc cgattcttgg gatttgtttg ggccaccaag
     4021 ccattgcaga agtctttggt ggtaagctag gtttggctcc aaaagtcatg catgggaaac
     4081 agagcaatat caactttgaa gcgccatctg ttttgtatca aggtattgag gatggccgtg
     4141 cggtcatgcg ttatcacagt attttgattg aggaaatgcc agaagacttt gaagtgacag
     4201 ctcgttcgac tgatgaccaa gccatcatgg ggattcaaca taaaaaccta ccgatttatg
     4261 gcttccagta ccatccagag agcattggaa cgccagacgg cttgtcttct attcggaatt
     4321 ttatcgagga ggttgtaaag tgaggaaact aggatgaaag agattattga aaaactagca
     4381 aaatttgaaa atttatcagg tgtggaaatg acggatgtca ttgagcgtat cgtaactggg
     4441 cgtgtaactg aagcgcagat tgcttctctc ctcttagctc ttaagatgaa gggggaaaca
     4501 cctgaagaac gcacagccat tgcccaagtc atgagaggac atgcccagca tattccaact
     4561 gagattcatg atgctatgga caactgtggt acaggtgggg acaagtcttt cagttttaat
     4621 atttccacaa ctgcagcctt tgtcttggct ggtggcggta ttcacatggc caagcatggt
     4681 aaccgctcga tttcttctaa atctggttcc gcagatgtcc tcgaagcctt gggaatcaat
     4741 cttgacctca aaccagctga actaggtaag gtctttgata aaactggaat cgtctttctc
     4801 ttcgctaaaa atatgcaccc agctatgaaa tacatcatgc cagctcgttt ggaattggga
     4861 attccaacga ttatgaactt gactggtcca ctgattcatc caatggcttt agaaacacag
     4921 cttcttggaa ttagtcgtcc agaactccta gaaagtacag ctcaggtttt gaaaaatatg
     4981 ggtcgcaaac gtgccatcgt ggttgctgga ccagaagggt tggatgaagc tggcttgaac
     5041 ggaacaacca agattgcact tcttgaaaat ggcgaaatca gcttgtcaag ctttactcca
     5101 gaggatttgg gaatggaagg ctatgctatg gaagatattc gtggtgggaa tgctcaggaa
     5161 aatgcagaaa ttttgcttag cgttctgaaa aacgaagcaa gtccattctt ggaaacgaca
     5221 gtcttgaatg ctggtcttgg tttctatgct aatggtaaga ttgatagcat caaggaagga
     5281 gttgccttgg cccgtcaagt gattgctaga ggcaaggccc ttgaaaaact cagactgtta
     5341 caggagtacc aaaaatgagt caggaatttt tagcacgaat cttagagcag aaggcgcgtg
     5401 aggtggagca gatgaagctg gagcaaatcc agcctctgcg ccagacctat cgcttggcag
     5461 aatttttgaa gaatcatcag gaccgcttgc aggtaatcgc tgaggtcaag aaagctagcc
     5521 ctagtttggg agatatcaat ctcgatgtgg atattgtgca acaggctcag acttatgaag
     5581 aaaacggagc agtgatgatt tcggtgttga cagatgaggt tttctttaaa gggcatttgg
     5641 attatctacg ggaaatttcc agtcaggtag agattccgac gctcaacaaa gactttatca
     5701 tagatgaaaa gcaaatcatc cgcgctcgca atgcaggtgc gacagttatc ttgcttattg
     5761 tggcagcctt gtccgaagaa cgcctcaagg aactgtatga ctacgcgaca gagcttggtc
     5821 tggaagtctt agtggagact cacaatctag ctgaactaga ggtagcccac agacttggtg
     5881 ctgagattat cggggtcaac aaccgcaact tgactacctt tgaggtcgac ttgcagacca
     5941 gtgtagattt agccccttac tttgaggaag gtcgctatta catttctgaa tctgccattt
     6001 tcacagggca ggatgcggaa cgactagccc catactttaa cggaattttg gtagggacag
     6061 ctcttatgca ggcagaaaat gtggcccaga gaatcaagga gttgcagatt gacaaaggtt
     6121 aaaatttgtg gactatcgac caaagaagcg gtggaaacag ccgtttcagc aggagccgac
     6181 tatatcggtt ttgtctttgc acctagtaaa agacaggtga ctttagaaga ggcagctgag
     6241 ttggcaaagc ttattcctgc agatgtgaaa aaggttggag tatttgtttc accaagtcgg
     6301 gtagaactgc tggaagcgat tgacaaagtt ggcttggact tggttcaagt tcacggtcag
     6361 gtggcagatg atttatttga gaatttgcct tgtgccagta ttcaggctgt gcaggtagat
     6421 ggaaatgggc atgtccccaa ttctcaggca gattatctac tctttgatgc ccctgtggca
     6481 ggaagtggcc agtcctttga ttggggtcaa ctggatacga ctggactagc acagcccttc
     6541 tttatcgcag gtggccttaa tgaagataat gtagtaaaag caattcaaca ttttactccc
     6601 tatgcagtag atgtatcgag cggagtggag acagatggac aaaaagatca tgaaaagatt
     6661 agaagattta tagagagggt aaagaatggc atatcaagaa ccaaataaag atggatttta
     6721 cggaaaattc ggcggacgtt ttgtcccaga aacattgatg acagcagttt tggagttgga
     6781 gaaggcctac cgtgaaagtc aggcagaccc aagtttccaa gaggaattaa accaactttt
     6841 gcgccagtat gtgggacgtg aaactcccct ttactacgca aaaaatttga cccagcatat
     6901 cggcggagcc aagatttatc tcaaacggga agaccttaac catacaggag cccacaagat
     6961 taacaatgcc ttaggacaag tttggcttgc caaacgcatg ggtaaaaaga aaattatcgc
     7021 agaaacgggt gctggtcagc acggtgtggc aactgcaact gctgcagccc tctttaacat
     7081 ggaatgtacc atctacatgg gtgaggaaga tgtcaaacgc caagccctca atgtcttccg
     7141 catggagctt ttgggagcca aggtcgaggc cgtgacagat ggttcgcgcg tgctcaagga
     7201 tgcggtcaat gcagcccttc gttcatgggt ggctaatatc gatgataccc actatatcct
     7261 tggttctgcc ttgggtcctc atccattccc agaaatcgtt cgtgacttcc aaagtgttat
     7321 tggtcgagaa gctaaacaac agtaccgtga cttgacaggt cgagatctgc cagatgccct
     7381 agtagcctgt gttggtggtg ggtcgaatgc tatcgggctc ttccatccct ttgtagaaga
     7441 tgagtcagta gctatgtatg gagctgaagc agcagggctt ggtgtggata cagagcacca
     7501 cgctgctacc ttgaccaagg gtcgtccagg tgtccttcac ggttccctta tggatgtgct
     7561 ccaagatgcc catggtcaaa ttcttgaagc cttctctatc tcagcaggtt tggactatcc
     7621 tggtatcggt ccagagcatt ctcactacca cgatattaaa cgtgccagct atgtccctgt
     7681 gacagacgaa gaagccttgg aaggatttca actcttgtct cgtgtggaag ggattatccc
     7741 agctttggaa tctagccatg ctatcgcttt tgcggtgaaa ttggccaaag aacttggacc
     7801 agaaaagtct atgattgtct gcctatcagg tcgtggggac aaggatgtgg ttcaagtcaa
     7861 agaccgcttg gaagcagatg cagcaaagaa gggagaagct catgcctaag acactaacag
     7921 aaaaattgaa tgctataaaa gtaactggaa aaggaatttt cgttccttat atcatggctg
     7981 gtgaccacga aaaaggtttg gacggtcttg ctgaaacaat tcacttttta gaagatttgg
     8041 gtgtctctgc tattgaagtg gggattccct tttcagaccc tgttgcagat ggacctgtta
     8101 tcgaagaagc tggcttgcgc agtttagccc acgggacctc tacccaggct ttagttgaaa
     8161 ccttgaaaac cattgaaaca gagattccac tggtcatcat gacctacttc aaccccctct
     8221 ttcagtacgg tgtggagaac tttgtcaaag atctggctga tacagctgtg aagggcttga
     8281 ttatcccaga cctgcctcat gaacatgcca actttgtaga accatttttg gcagatacag
     8341 atatcgcctt gattccttta gtaagcttga ccacaggaat tgagcgccag aaagagttga
     8401 ttgaaggggc ggagggattc gtctatgccg ttgccatcaa tggggtgaca gggaaatcag
     8461 gcaattaccg tgcagatttg gacaagcact tggcgcaact tcatcaagtg gccgacatcc
     8521 cagtcttgac aggttttggt gtatctagtc aagccgatct ggaacgcttc aatgcggtgt
     8581 cagatggtgt tatcgtcggt tcaaaaatag taaaagctct ccaccaagga gagccgattc
     8641 aggattttat cagacaagca gtagcttacc aaaaataatc aaacaagtag caagtaagag
     8701 gaaaggcacg aaaggaagtc tttccttttt cttttgcagg ataaag
//
LOCUS       DAVKBC010000059         8745 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVKBC010000059 DAVKBC010000000
VERSION     DAVKBC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.059"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..170
                     /locus_tag="VWX64_001834"
     CDS             <1..170
                     /locus_tag="VWX64_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU9191252.1"
                     /translation="ELKSLGKWYVSTGKEWICHSDDDLEEFKNLFLNFINPEEWDTIS
                     FDSDFMPFQQS"
     gene            complement(449..1210)
                     /locus_tag="VWX64_001835"
     CDS             complement(449..1210)
                     /locus_tag="VWX64_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9191253.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(1392..2354)
                     /gene="nrdF"
                     /locus_tag="VWX64_001836"
     CDS             complement(1392..2354)
                     /gene="nrdF"
                     /locus_tag="VWX64_001836"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU9191254.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(2542..4701)
                     /gene="nrdE"
                     /locus_tag="VWX64_001837"
     CDS             complement(2542..4701)
                     /gene="nrdE"
                     /locus_tag="VWX64_001837"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU9191255.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(4782..5000)
                     /gene="nrdH"
                     /locus_tag="VWX64_001838"
     CDS             complement(4782..5000)
                     /gene="nrdH"
                     /locus_tag="VWX64_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU9191256.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            5351..5614
                     /locus_tag="VWX64_001839"
     CDS             5351..5614
                     /locus_tag="VWX64_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU9191257.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            5620..7353
                     /gene="ptsP"
                     /locus_tag="VWX64_001840"
     CDS             5620..7353
                     /gene="ptsP"
                     /locus_tag="VWX64_001840"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU9191258.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            7608..>8745
                     /gene="phtA"
                     /locus_tag="VWX64_001841"
     CDS             7608..>8745
                     /gene="phtA"
                     /locus_tag="VWX64_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEU9191259.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEQPSLQPTPEPSP"
BASE COUNT         2719 a         1621 c         1793 g         2612 t
ORIGIN      
        1 aagaattgaa aagtcttgga aaatggtatg tctcgactgg taaagaatgg atttgtcatt
       61 cagatgatga tctggaagaa tttaaaaatc tatttttaaa ttttatcaat cctgaagaat
      121 gggatactat ctcctttgat tcagatttta tgccgtttca acaatcgtaa ccaatttctc
      181 aaaaaagtta aatcttatat ttagtactct gtaaaactct tatctaatca cgttgcttat
      241 actcaatgaa aatcaaagag caactttaaa ctaggaagcg agtcgcagat ttctcaatgt
      301 atagctttga ggaattgggc aaaaagtctt tgatatagaa aaaagcatag tatcaggtgt
      361 ttcaacacct gatactatgc tttttattgt gggaagattt actttttttc ttctgaaatt
      421 gagttgttac ccaggctctt tcagtttatt aaggcttgat gactttaatg tgtttagata
      481 gcttaaaaag gattgaatca cttagtttag aatctgaaac aatagtatca agatttgata
      541 tattataaaa agtataaaaa tcaaacttat tgaacttact atgatctgcg agtaaatatt
      601 ttttattaga attatttaaa gcgatgcgtt gagcctctcc ctcttcctcg ctaaaagtag
      661 ctagagctcc gttttgaata ccattacagc taacgaaagc tttagaaaat tggagattag
      721 agagattttg tagggtcaat gtgccaacaa aagcacctgt aatatcgcga taatttccac
      781 ctatcaaaat caaatctgtt aattttcgtt cgcttaaaat cagaaaaaca ggtagactgt
      841 tggttacgac gcggatattg tcaataggca actcacgcgc aaaaaactct aatgttgttc
      901 ctggtccaat gaaaatagtt tctctttctt ctactagact gcctgcaaaa tgggctattt
      961 cttgtttttc tgccgtttgg agggcttgtt tttcaatatt tgatcgctca ttagtcaaaa
     1021 gggagttggt tcgaagtttt tcagctccac catgcacacg aatcagcaaa tctttatcag
     1081 ctaattcctg taaatagcgc cttgcagtca tatctgaaac ggctatttcg tccataatct
     1141 gtttaactgt tatggttcct ttactattta ctatctctaa aattttggtt aatttttctt
     1201 gtttgagcat attatcacct cgtttcctac tactatctta ccataaacaa actcatcatt
     1261 caaatacaaa aacaacaaaa tgaaacaaaa acaaaaatat cgaagtttgt tttcaaaact
     1321 ttcgatattt ttgttgggtt ataactttga tgtttctagt ttactttttg atgattgaga
     1381 gtgatggaga attagtctaa accgtagtta tagtcatcgt cttgcatggc ttcaacttcg
     1441 ccaagaaggt aaccatttcc gacttgagag aagaagtcat ggttggaagt tcctgttgaa
     1501 ataccgttca taacgattgg gttgacatct tcagctgaat ctgggaaaag tggatcttgt
     1561 cccatgttca tgagagcttt attggcattg tagcgaagga aggttttaac ctcttcagtc
     1621 caaccaacac cgtcataaag actctctgtg tagccttctt cattttcata aagagtatag
     1681 agtaggtcgt acatccattc tttgagtttt tcttgctctt cttcaggcaa ttcattgaaa
     1741 ccaagttgga atttgtaacc aatgtaggtt ccgtgaacag actcgtcacg aataatcaat
     1801 ttaatgattt ctgcaacgtt ggctagtttg ttgttaccga gatagtagag gggagtgaag
     1861 aaaccagagt agaagaggaa ggtttcgagg aagacgctgg caactttctt ttcaagtggg
     1921 ctgccgttta ggtagatttc gttgacaatc tcagccttct tttgtaggta aggattggta
     1981 ttggtccatt cgaaaatttc ttcaatctca gccttagtat tcaaggtaga aaagattgat
     2041 gagtaagatt tagcgtggac agattccata aattggatgt tattgaaaac agcttcctca
     2101 tgtggtgtac ggatgtctgc gcgaagggct tgaaccccag tttcagattg catagtgtca
     2161 agaagggtta aaccaccaaa aacttttccg accaagtctt tctctttgtt agatagcttt
     2221 ctccagtcat ccaagtcgtt tgataaggga atacgtgtat cgagccaaaa ttgctccgtc
     2281 agtttttccc aagttgattt gtcgatgaca tcttcgatgg cattccagtt aatggctttg
     2341 tagtaagttt ccatttaaaa tctctttctg tgtttagtat tgcgaactca caattatttc
     2401 tactttacca taattctata ggagtatcgc acaaaaagtc ggaagcccga cttttaaaat
     2461 gttacataaa ttatgttatg acatagtaga tttgatttta tctgtgctgc ttagggaaaa
     2521 ataatgtttc tatgctagaa actaaatcac acagctttca cattggttgg cgccgacttc
     2581 tccaccgtca tctgtaaagg tacggacgta gtagatagac ttgattccct tgttaaaggc
     2641 atagttacga aggatggaca agtcacgtgt cgtttgttta ttttccctct tccattcgta
     2701 aaggcctttt ggaatgtcac tacgcatgaa gagggtgagt gaaagtcctt gatccacgtg
     2761 ttcagtcgca gcagcgtaaa catcgatgac tttacgcata tccatatcgt aggcagaagt
     2821 gtagtaagga atggtttctg tagacaagcc agcagcaggg tagtagattt taccaatttt
     2881 cttctcttgg cgttcttcga tacgttgcgt aatcgggtgg atagaagcag aaacgtcgtt
     2941 gatatagctg atagaaccat ttggcgctac agcaaggcga ttttggtggt aaagaccatc
     3001 ttcttgaacc ttgtcgcgaa gttcagccca atcagcaaca ccagggataa agacattttt
     3061 gaagagttct ttaacacggt ctgatgttgg aacaaattca ccagttacat acttgtcaaa
     3121 gtaacttccg ttagcatagt ctgatttttc aaagttgtgg aaggtaatac cacgttcacg
     3181 cgcaatattg tttgactcta ccaaggtcca gtagttcata agcataaagt agatgcttgt
     3241 aaattcaaca gactcaggtg aaccatattc aatgagttgt tgggcaaggt agctgtgcag
     3301 tcccatggca ccgagaccaa aggtgtgggc ttggctattt ccatggtcaa tcgttggtac
     3361 agctacgata tgtgaactat ctgtaacgaa agtaagggca cgaaccatag cacggataga
     3421 acgaccaaaa tcaggtgaag tcatcatgtt aaccacgttg gttgaaccca ggttacatga
     3481 aacatctgtt cccatttgaa ggaattcttg agcatcgttg atcaagcttg gttcttgaac
     3541 ttgaagaatc tcagaacaca agttactcat gataatcttt ccatcaacag gatttgcacg
     3601 gttagccgta tctatgttga ctacataagg atagccagac tcttgttgca atttagagat
     3661 ttcagtttcc aaatcccgcg ccttgatttt tgtcttgcga atatttggat ttgcgaccaa
     3721 ttcatcgtat ttttcagtaa tgtcgatgta attgaatggc acaccgtatt ctttttctac
     3781 agagtaaggg ctgaagaggt acatttcttc atttttacga gccaattcgt agaatttatc
     3841 aggtactaca acaccaagtg atagagtctt gacacgtact ttttcatcag cgttttcttt
     3901 cttagttgaa aggaaagcga tgatatctgg gtgaaagacg ttgaggtaga caacaccggc
     3961 accttgacgt tgccccaatt ggttggagta agagaagctg tcttcaaaaa gcttcataac
     4021 aggaacgaca cctgaagcag ctccttcata gcctttgata ggtgcaccag cttcacgaag
     4081 gttgctgagg gtaattccca caccaccacc aatacgtgaa agttgaagag ctgagttgat
     4141 agaacgtccg atagagttca tatcatccgt cacttggatt aggaaacaag ataccaactc
     4201 cccacgacga gcacgtccag cattcaagaa ggaaggagta gcaggttggt agcgttggtg
     4261 gatgatttca ttggcaatat cgattgcaac agcttcattc ccatcagcga aataaagggc
     4321 gttgaagaag acacggtctt ccatattttc aagatagtat tcaccgtcat tagtctttaa
     4381 ggcatattga ttgtaaaatt tataagctgc catgaatgac ttgaattgga agttttggtc
     4441 tttgataaat tgagccaatt cttccaagaa ctctggacgg tatttcttga taaaggctgt
     4501 ttcgatgtag ttgtgttcaa tgaggtaatt gattttgtct ttgattgaat caaaaaccat
     4561 agtgtttgga actacatttt ctttaaagaa agcatccaag gcttccttat ctttatgaag
     4621 catgatttgt ccattaacag gacggttaat ttcgttatta agacggaagt aagtcacgtc
     4681 ttcaagatgt tttaatccca taaaatttcc cttatctaat tacaaaagaa aggcttctaa
     4741 gttagcccta aaagcagttt cttctggatg atgtactaag attatgctaa ttgtttcagt
     4801 tttcctggtt ggaaacctga aaagacttca gttggtgttt ggataacagg agctgcgcta
     4861 aaaccgagct ctttaacttg atcgacgtac tcaggttgct catcaagatt gatttcacga
     4921 taagagacat tattactgtc caagaaacgc ttggtcattt tacattggac acaattgttt
     4981 ttagaataaa cggttaccat tgtgtaactc ctcttcaaaa tttaatacta tcttagtata
     5041 tcagaaaata aaattttgtc aatgatttaa actaaatata gtggtgttct tttgttgttt
     5101 ttatatataa acacaatata tagtgtttgt attgtgaaat agcaatgatt atcctataaa
     5161 ttgtttttga agaaactata tcctgtgttt tgttatctag gatagaagat tttcagcaag
     5221 ttatctgaaa ggaaattgaa ggaaaatcca gaaaatgctt gaaaaaaatc ctagaagatg
     5281 gtataatact aaattgtaag ggttatcaca tataactcaa aaaaagaaag aacaaaagga
     5341 gagtcaaact atggcttcta aagatttcca cgtagtggca gaaacaggta ttcacgcacg
     5401 tccagcaaca ttgttggtac aaactgctag caaatttgct tcagatatca ctcttgagta
     5461 caaaggtaaa tcagttaacc ttaaatcaat tatgggtgtt atgagtcttg gtgttggtca
     5521 aggtgctgac gtaactatct cagctgaagg tgcagatgca gatgacgcta tcgctgcaat
     5581 ctcagaaaca atggaaaaag aaggattggc ataagggaaa tgacagaaat gcttaaagga
     5641 atcgcagcat ctgacggtgt tgcagttgca aaagcatatc tactcgttca gccggatttg
     5701 tcatttgaga ctattacagt cgaagataca aacgcagaag aagctcgcct tgatgccgct
     5761 ctacaggcat cacaagacga gctttctgtt attcgcgaga aagcagtagg tacgctcggt
     5821 gaagaagcag ctcaagtttt tgatgctcac ttaatggttc ttgctgaccc agaaatgatc
     5881 agccaaatca aggaaactat ccgtgcgaag aaagtgaatg cagaagcagg tctgaaagaa
     5941 gttacagata tgtttatcac tatctttgaa ggcatggaag acaacccata catgcaagaa
     6001 cgcgcagcgg atatccgcga cgtgacaaaa cgtgtattgg caaaccttct tggtaaaaaa
     6061 ttgccaaacc cagcttctat caatgaagaa gtgattgtga ttgcgcatga cttgactcct
     6121 tcagatacag ctcaattgga caaaaacttt gtaaaagctt ttgtaaccaa cattggtgga
     6181 cgtacaagcc actcagctat catggcacgt acacttgaaa ttgctgctgt attaggtaca
     6241 aacaacatca ctgaaatcgt taaagacggt gacatccttg ctgttaacgg gatcactgga
     6301 gaagtgatta tcaacccaac agatgaacaa gcggcagaat ttaaagcagc tggtgaagcc
     6361 tatgcgaaac aaaaagctga atgggcactt ttgaaagatg ctcaaacagt gactgctgac
     6421 ggtaaacact tcgagttggc tgccaatatt ggtactccaa aagacgttga aggtgttaac
     6481 aacaacggtg cagaagctgt tggactttac cgtacagagt tcttgtacat ggattctcaa
     6541 gacttcccaa ctgaagatga gcagtatgaa gcatacaagg ctgttcttga aggaatgaac
     6601 ggtaaacctg ttgtcgttcg tacaatggat atcggtggag ataaggaact tccttacttc
     6661 gatatgcctc acgaaatgaa cccattcctt ggattccgtg ctcttcgtat ctctatctct
     6721 gagactggag atgctatgtt ccgcacacaa atccgtgctc ttcttcgtgc gtctgttcac
     6781 ggtcaattgc gtatcatgtt cccaatggtt gcgctcttga aagaattccg tgcagcgaaa
     6841 gcagtctttg atgaagaaaa agcaaacctt cttgctgaag gtgttgcagt tgcggataac
     6901 attcaagttg gtatcatgat cgagattcct gcagcggcta tgcttgcaga ccaatttgct
     6961 aaagaagttg acttcttctc aattggtaca aatgacttga tccaatatac aatggcagca
     7021 gaccgtatga acgaacaagt ttcatacctt taccaaccat acaacccatc aatcctacgc
     7081 ttgattaaca atgtgatcaa agcagctcac gctgaaggta aatgggctgg tatgtgtggt
     7141 gagatggctg gtgaccaaca agctgttcca cttcttgtcg gaatgggctt ggatgagttc
     7201 tctatgtcag caacatctgt acttcgtaca cgcagcttga tgaagaaact cgacacagct
     7261 aagatggaag agtacgcaaa ccgtgccctt acagaatgct caacaatgga agaagttctt
     7321 gaacttcaaa aagaatacgt taattttgat taatcgaaaa gtccctgcaa ctcagttaca
     7381 gggacttttt ttgatatttt aaaaagaatt ttcaagaaaa tctttcttat aaaaagtcca
     7441 accttgaaaa agtagtggtc agaacaaaaa atacttaaat ggttcataaa attcttgaca
     7501 agttggagat ttaggagtaa actattaacc agttaagtaa tagagaggag tttctgcaat
     7561 ttagaaatga attgcaacta gaaatatcaa atagaaagag agtttcgatg aaaattaata
     7621 agaaatacct tgttggttct gcggcagctt tgattttaag tgtttgttct tacgagttgg
     7681 gactgtatca agctagaacg gttaaggaaa ataatcgtgt ttcctatata gatggaaaac
     7741 aagcgacgca aaaaacggag aatttgactc ctgatgaggt tagcaagcgt gaaggaatca
     7801 atgctgagca aatcgtcatc aagataacag accaaggcta tgtcacttca catggcgacc
     7861 actatcatta ttacaatggt aaggttcctt atgatgcgat tttcagtgaa gaattactca
     7921 tgaaagatcc aaactataag ctaaaagatg aggatattgt taatgaggtc aagggtggat
     7981 atgttatcaa ggtagatgga aaatactatg tttaccttaa ggatgctgcc cacgcggata
     8041 acgtccgtac aaaagaggaa atcaatcgac aaaaacaaga acatagtcag catcgtgaag
     8101 gagggacttc aacaaacgat ggtgcggtag cctttgcacg ttcacaggga cgctacacca
     8161 cagatgatgg gtatatcttc aatgcatctg atatcattga ggacactggt gatgcttata
     8221 tcgttcctca tggagatcat taccattaca ttcctaagaa tgagttatca gctagcgagt
     8281 tggctgctgc agaagccttc ctatctggtc gggaaaatct gtcaaattta agaacctatc
     8341 gccgacaaaa tagcgataac actccaagaa caaactgggt accttctgta agcaatccag
     8401 gaactacaaa tactaacaca agcaacaaca gcaacactaa cagtcaagca agtcaaagta
     8461 atgacattga tagtctcttg aaacagctct acaaactgcc tttgagtcaa cgacatgtgg
     8521 aatcggatgg ccttattttc gacccagcgc aaatcacaag tcgaaccgcc agaggtgtag
     8581 ctgtccctca tggtaaccat taccacttta tcccttatga acaaatgtct gaattggaag
     8641 aacgaattgc tcgtattatt ccccttcgtt atcgttcaaa ccattgggta ccagattcaa
     8701 gaccagaaca accaagtcta caaccgactc cagaacctag tccaa
//
LOCUS       DAVKBC010000060         8564 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVKBC010000060 DAVKBC010000000
VERSION     DAVKBC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8564
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.060"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            12..1037
                     /locus_tag="VWX64_001842"
     CDS             12..1037
                     /locus_tag="VWX64_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9191260.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1027..2034
                     /locus_tag="VWX64_001843"
     CDS             1027..2034
                     /locus_tag="VWX64_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9191261.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2034..3041
                     /locus_tag="VWX64_001844"
     CDS             2034..3041
                     /locus_tag="VWX64_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9191262.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3041..3835
                     /locus_tag="VWX64_001845"
     CDS             3041..3835
                     /locus_tag="VWX64_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191263.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHINS"
     gene            4223..4612
                     /locus_tag="VWX64_001846"
     CDS             4223..4612
                     /locus_tag="VWX64_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9191264.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            4578..4892
                     /locus_tag="VWX64_001847"
     CDS             4578..4892
                     /locus_tag="VWX64_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191265.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            5577..5738
                     /locus_tag="VWX64_001848"
     CDS             5577..5738
                     /locus_tag="VWX64_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191266.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            5830..6314
                     /locus_tag="VWX64_001849"
                     /pseudo
     CDS             5830..6314
                     /locus_tag="VWX64_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861739.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            6348..7508
                     /locus_tag="VWX64_001850"
     CDS             6348..7508
                     /locus_tag="VWX64_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU9191267.1"
                     /translation="MFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQN
                     GKNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEA
                     IVSDEVWQAAQVKLKSQAKRYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKK
                     DGTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQE
                     KINMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLY
                     RMYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISA
                     LISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            7776..8342
                     /locus_tag="VWX64_001851"
     CDS             7776..8342
                     /locus_tag="VWX64_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191268.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
BASE COUNT         3224 a         1155 c         1598 g         2587 t
ORIGIN      
        1 aaggagtttt tatgaaaaac aaattttttc taatagctat tttagctatg tgtatagttt
       61 ttagcgcttg ttcttctaat tctgttaaaa atgaagaaaa tacttctaaa gagcatgcgc
      121 ctgataaaat agttttagat catgctttcg gtcaaactat attagataaa aaacctgaaa
      181 gagttgcaac tattgcttgg ggaaatcatg atgtagcatt agctttagga atagttcctg
      241 ttggattttc aaaagcaaat tacggtgtaa gtgctgataa aggagtttta ccatggacag
      301 aagaaaaaat caaagaacta aatggtaaag ctaacctatt tgacgatttg gatggactta
      361 actttgaagc aatatcaaat tctaaaccag atgttatctt agcaggttat tctggtataa
      421 ctaaagaaga ttatgacact ctatcaaaaa ttgctcctgt agcagcatac aaatctaaac
      481 cttggcaaac tttatggaga gatatgatta aaattgattc aaaagcctta ggtatggaaa
      541 aagaaggtga tgagttaatc aaaaatactg aagctcgtat atccaaagaa ttagaaaaac
      601 atccagaaat caaaggaaaa atcaaaggaa aaaaagtatt atttactatg attaatgctg
      661 cagatacatc aaaattctgg atttatacta gcaaagatcc aagagcaaat tatttaacag
      721 atttaggtct agttttccct gaatcattaa aagaatttga gagtgaagat agttttgcaa
      781 aggaaatttc tgcagaagaa gcaaataaga taaatgatgc tgatgtaatc ataacttatg
      841 gtgatgataa aactcttgaa gctttacaaa aagatcctct tttaggtaaa ataaatgcaa
      901 ttaaaaatgg tgccgttgct gtaattccag ataatacacc gttagcagcc tcatgcactc
      961 caacaccact ttcaataaac tatactattg aagaatacct aaatctttta ggaaatgcat
     1021 gcaaaaatgc gaaataaaaa acaaataaac ctaggcataa tttttgtaat ctgcctaggt
     1081 cttcttatta caatattttt gtcattaaag cttggaacaa aagaaattaa tatcagagat
     1141 tttttagcag cttttggaat gggcaataca aatgatgatt ttattaaatc aattatatat
     1201 aaaagaatac ctagaactat ttttgcaatt ttagcaggtt ctagtcttgc cataagcggt
     1261 gtattgatgc aatcagttac tagaaaccca atagctgatc caggtatact cggtataaac
     1321 acaggagcaa gtcttagtgt agtaattggt ctttcttttt taggaatttc atcaagcata
     1381 agccatataa gttttgcaat cattggtggc ttagtaagtg caatttttgt atacgcgatt
     1441 gctgtaagcg gaaaagcagg ccttacccct ataaaacttg ccttatcagg aacttgtgtt
     1501 agtatggctt taagcagttt tgtaagtttt ttaattttac cgaataataa cgtcttagac
     1561 aaatttagat tttggcaaat aggtagcctt ggagcagcta cattatcttc tatatctaca
     1621 ctactacctt ttataatttt aggtcacttg atagctatat ttatttcatc agatttaaac
     1681 gctttagcta tgggtgatga aatggctgtt ggtcttggag ttaatgttaa taggataaga
     1741 tcacttgcaa taattgcaag tgtgctttta tgttcaagta ttactgcaat tggtggacct
     1801 attggcttcg taggtcttat agttcctcac ttttgtggct tatttataag caaagatata
     1861 cgcacaatga ccatttcttc atcttttata ggtgcagagc tcttgcttat atgtgatata
     1921 atcggccgta tgttaggtaa accaggtgaa attgaagtag ggataattac tgcaataatc
     1981 gggggtccag tacttattta tgtaactatg aaaaatagag gggttaataa ctaatgcaaa
     2041 atttaattat aggtattcaa aaaagaaaaa atagaataac actattttcc tcactatttt
     2101 tattaataat aatcagtcta tcatttttca ttttacttat cggagatgaa agttattctt
     2161 tttcaacttt gattaaagtc ttaaatagtg aaactgttcc tggagctagt ttttcgatta
     2221 tggaaattag attaccaaaa ttattagcag gaattatagc tggctggtct tttggattgg
     2281 caggatttat ctttcaaact atgttaagaa atcctcttgc aagtcctgat ataatcggtg
     2341 tcacaagttc ttcatctatt gcagcggtct tttgcatatt ggtattaaaa acaaatagtt
     2401 taactactgg aattatttca ataacttgtg gactaacatc atctttaata ttatttttac
     2461 tagctaaaaa agatggtttt tcagcagcaa gactgataat attaggtatt ggttttcaag
     2521 ctgtcacaag agcaggcacc tcatttttat tgttgaaagt agcaagatat gaattacaag
     2581 aagttatgag atggctcagt ggctctttat cttttacaaa gttagatgac atacctcttg
     2641 ttctaatagt aagtattatt gctactatat tagttttatt ttttaataaa agactagaaa
     2701 ttattgaact tggtgaagaa atagcaatcg gacttggagc aaatcccgag ctttcaaggc
     2761 ttgttttaat tttttgcgct gtatctttaa ctgctttttc tacttcaatt acaggaccaa
     2821 tagcttgtat atctttttta gctggtccca tagccttaaa tattggcaag aaaagaagcc
     2881 caatattagc tggattggtt ggaattttac tagttttgtt atcagacata ttctctcaaa
     2941 atattttacc agctagatat ccagtaggtg ttgtaactgg cttgttaggt tcaccatact
     3001 taatatactt actaataaaa atgaacagga ggaatatata atgaaaggtc tgtggtcaaa
     3061 taatcttacc tgcggttatg atgaaaaaat aatcttggaa aatataaata taaaaatacc
     3121 tgaagaaaaa atatcagtta ttattgggtc aaatggttgt gggaaatcaa cactcattaa
     3181 aaccttgtct cgacttataa agccattaga gggagaagta ttgcttgata ataaatcaat
     3241 taattcttat aaagaaaaag atttagcaaa acacatagct atattacctc aatctccaat
     3301 aatccctgaa tcaataacag tagctgatct tgtaagccgt ggtcgtttcc cctacagaaa
     3361 gccttttaag agtcttggaa aagatgacct tgaaataata aacagatcaa tggttaaggc
     3421 caatgttgaa gatctagcaa ataacctagt tgaagaactt tctgggggtc aaaggcaaag
     3481 agtatggata gctctagccc tagcccaaga tacaagtatc ctacttttag atgagccaac
     3541 tacttacttg gatatctcat atcaaataga actattagac ctcttgactg atctaaacca
     3601 aaaatataag acaaccattt gcatgatttt gcacgatata aatctaacag caagatacgc
     3661 tgattaccta tttgcaatta aagaaggtaa acttgttgca gagggaaagc ctgaagatat
     3721 actaaatgat aaactagtta aagatatctt taatcttgaa gcaaaaatta tacgtgaccc
     3781 tatttccaat tcgcctctaa tgattcctat tggcaagcac catattaact cttaataatt
     3841 gaatattgga attcatttaa aagtcgcaaa ttttgaactg accctcaaaa gttaggccaa
     3901 aaaactaact aaaggaggtc agttttttaa tggcaaatac agcacagaat ttaagataaa
     3961 attagtaaaa gaatatcatg aatgaaaaat aggatataga gaataacagc aatattaaaa
     4021 agatcaggac tgataataaa caaaaagaaa gtacaacgac tagttcaaaa gctaaaactt
     4081 caagtaaaaa gttattcaag aaaatctaga aaatactcat cctacaaagg acaggtagga
     4141 aaaatatcag acaacaaaat aaaaagaaat atttattacc gaaaaaaagg ggaaatcgag
     4201 tcaagtacca acaggctcat ctattccaaa aagatattta ctcgatggaa aaactcctag
     4261 aattagtgct acaaatattg acaatggtat cttaggttac tacgaagata tagatgataa
     4321 aaattataga gtttttgaaa attttatatc tgtttcattt ttaggagcag tcttttatca
     4381 taaatataaa gcaagcctag atatgaaaat tcattgttta aaattaaaaa ataaagaatt
     4441 gaataaagaa gtagcattct atttaacttc aattattagg caagctttaa aaaatactga
     4501 atataaagat caaatatcta gcacagtatt gccagatatc aaaattaaat taccgataga
     4561 cagtagaggt actccagatt ggaattacat ggaaagatat agagatagat aaagagagag
     4621 agggagagat agataaaaag tccaccccca ttttttatgg agaattcaaa aatgtaaggt
     4681 taagcaaaga agaatataaa aatctaaaag aaaaattaaa ctcacacaca gatataatga
     4741 taaataaact atccagatac atggaaagca gtggtaagac ctatcaaaac cactatgtga
     4801 caatcttaaa atggtatgaa gaagataaag acaaactaag acagaaaggt ttaaataaaa
     4861 aaatgaatta tgatgtagga gaatctttat agataaaaag aggtggaaag gcactattaa
     4921 agactttaag tctaaaaagg tatcaaagta tgccagagat aaaaaaaata taaatatgac
     4981 actttaaagg cgattagaaa attaaagaaa tgctagaaga cttttagatg acagttacca
     5041 agagggtcta attttcactg ctatttatgc agtgggaatt ggaccttttt atataagcaa
     5101 attctatttc aaaattggtt accaagaaag acttcttttc actgttaagt ataagagggt
     5161 aatttataga attttgttac atcaagataa atattttctg atggtcaaat tttaaaaaga
     5221 ttaataactc tcgataaatt ttgaacctta acaattgaat agaccaagac aagacgttaa
     5281 ttatttttgg agcgtaataa cctatccgtc aagatctttc ggctgaataa ttcggcaaaa
     5341 aaagttctgc taagcaaaaa gaaagtgagc gataagtaag agtttgaata tagggaggga
     5401 taccctatcc gctatgaaga aaatgagggt aatgatactt ctaaggttga agccggctca
     5461 tccggaatag aggcggaagt gagattccta tgttgctaat ccaaagcact tgtcaatgtc
     5521 aaaaaactta attaaacaaa taattattag atataaaact ttagaggagg tatatattgg
     5581 acaatgactg gaatggattg gctgatttaa tagcaaatct gattgcaaaa tatgctggtg
     5641 ctttagattt agataatcta cccgatccaa cgccagcaaa aaatcaagag atgaaaaata
     5701 gttttgacat ggcaaaaaca caaattgaga cggactaata aaagtgttat aatatacttg
     5761 aaatgatagt ccaaacttaa attaaaaaaa ttatatatga tatagaaaaa ttatattgag
     5821 gttaatacta tgtcaaaaga aaaaataaaa gtatacctct atacacgagt atctacgtca
     5881 atacagatag aggggtattc gttagaggca caaaaatcac gaatgaaagc ttttgctatt
     5941 tacaacgatt atgaaattgt tggagagtat gaagatgccg ggaagtctgg caagtctatt
     6001 gaaggtagaa tacagttcaa tcgaatgatg gaagatataa aatctggaaa agatggagta
     6061 tcttttgttc ttgtgtttaa gttatcaaga tttgcaagaa atgccgctga tgttctttct
     6121 acacttcaga taatgcagga ttatggagtt aatcttatct gcgttgaaga tggcattgat
     6181 tcatctaaag atgctgggaa actaatgatt tctgttttat cagctgtggc tgaaatagaa
     6241 agagaaaaca tccgtattca aacaatggaa ggtcgcattc aaaggcaagg gaaggaaaat
     6301 ggaatggtgg ctttgctccg tatggatata aacttgaaga cggcaagctg tttataaatg
     6361 aggaagaggc agttgcaata agaacgattt tcgaccagta tgtaaatact acgataggag
     6421 ccaatgggat atctaaatac ttagagaatc atggaattag aaaaatccca agacagaatg
     6481 gtaagaatcc tttgtttgat gcaggtctta taagaaagat attaaagaat cctgtatata
     6541 atgggaaaat agcatttgga agaagaactt tagaaaaagt tcatggtaca agaaatgaat
     6601 ataagcaggt tgaacaagat gaatatctaa tatctgaagg gatacatgaa gctatagttt
     6661 ccgatgaagt ttggcaagct gctcaggtta agctaaaatc tcaagcaaag agatatgagc
     6721 atgtgaataa aggaaaagat acacgcacac acttgctttc tggaattgta aaatgcccga
     6781 tatgtggagt gggaatgttt gggaacaagt gtatcaagaa aaagaaagat ggcacaaagt
     6841 ataaagattt ttattactat ggttgtaaac ataggcagat gataagaggt cataagtgta
     6901 cattcagtaa gcaaattaga gaagaattgt tagatgatgc tgttgcagag gtgattgtca
     6961 agatagtaag taatccgaaa tttgcttcta tgatgcaaga aaaaatcaac atgaaggtgg
     7021 atacctctga aatagaaaaa gaaatagata attaccaaaa ggaattgaga aagagtcatt
     7081 ctacaaagtt taagctaatt gaggaaatag ataatttaga tgttgaagat aagcattata
     7141 agagaaggaa acaggattta gatgatagac tatatcgtat gtatgacaaa atagatgaat
     7201 tagaatcatc actaattgat gcgaaagcaa agaaacagac tattgaagct gaaaagctta
     7261 caggagataa catatataag gttttgatct attttgataa gctctataaa gtcatgaatg
     7321 atgtagagcg taggcagtta atttcagctt tgatttctga aattcaagtt tatgaagaaa
     7381 aacaatctaa cggacaatgg ctaaaatcca ttacttttaa gctaccaatt atagaagaaa
     7441 atctcaacat agatttggac aatgatgaac aagttgaatg tgtaagttta ttagagaaac
     7501 gtagttaatc ctcaaaaggt tccccaaacc ttttgagtcc cactgacgca tcacgctgag
     7561 gcggtatcac tgcttgtacg agttgaagca tcagcgaagt aaaagtagat gttcagccaa
     7621 tgcgacgagg tgagaccgaa ggtcgataag gtgtgttctg ggtataggac tcgtaaagta
     7681 agtaggaaat atgatgagat gatacagaga gcctgaattg gtcaggtgac gtgcttattt
     7741 acattagcct gataatgaaa atggagagat tattgatggt tatattggaa ttgtaccaaa
     7801 atgattattc taaagattta gtagcatttg attccataga agatgggaaa gcctttgtag
     7861 ctcaaatccc gggatacact ctggaaacag aagatggttt tgaagtggag tattttaatc
     7921 ctaaaaacat accggattat atggaaatta tttttaacgg aaatattgtt cctttatcta
     7981 aatttatgtt cgatcctgag gaaaatgtaa acattatttg gaaagagatt tcaaatttat
     8041 ccctcaaaaa tgatagagtg atcgaaggat attcaaaaat tgatgcatat gtcgttaaca
     8101 accatgaagt taaagcctat gtcgaaacaa gagaaacgaa ctatcgtaaa gcaaaagact
     8161 tcttagaaag ccgcggatat gaaatcgaca gaagcttttt cggaagtgaa gacggtgaag
     8221 cgattcttta cagaaaaaaa gggatcgaag tttggcattt cttgtgtcac ttagacccaa
     8281 tgtttgtaga gattgaagat gtagaaggat atgttaaaga agaagttgga gagattcaat
     8341 agtcaaccaa agttccttgt gagtatatac ctttgctagt aaaagagtca aaacgttata
     8401 acgaaggggg gtaagaaaac ccttgagtgt aagtcttttt cttgtttaga gggaaagtat
     8461 tagagtagcc gctcataatt tatactagat ttgataactg atttgagaca gattttattt
     8521 ctataaatat tgtgaaaatt ttttaatacc aaagatttaa agtt
//
LOCUS       DAVKBC010000061         8250 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVKBC010000061 DAVKBC010000000
VERSION     DAVKBC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8250
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.061"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            10..456
                     /gene="argR"
                     /locus_tag="VWX64_001852"
     CDS             10..456
                     /gene="argR"
                     /locus_tag="VWX64_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9191269.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            507..3041
                     /gene="mutS"
                     /locus_tag="VWX64_001853"
     CDS             507..3041
                     /gene="mutS"
                     /locus_tag="VWX64_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU9191270.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREESA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQYLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            3188..4882
                     /gene="patA"
                     /locus_tag="VWX64_001854"
     CDS             3188..4882
                     /gene="patA"
                     /locus_tag="VWX64_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU9191271.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SNELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(5200..5463)
                     /locus_tag="VWX64_001855"
                     /pseudo
     CDS             complement(5200..5463)
                     /locus_tag="VWX64_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            5657..7423
                     /gene="patB"
                     /locus_tag="VWX64_001856"
     CDS             5657..7423
                     /gene="patB"
                     /locus_tag="VWX64_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU9191272.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            7562..>8250
                     /locus_tag="VWX64_001857"
     CDS             7562..>8250
                     /locus_tag="VWX64_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9191273.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
BASE COUNT         2304 a         1595 c         1949 g         2402 t
ORIGIN      
        1 gaggatttta tgagaaaaag agatcgtcat cagttaataa aaaaaatgat tactgaggag
       61 aaattaagta cacaaaaaga aattcaagat cggttggagg cgcacaatgt ttgtgtgacg
      121 cagacaacct tgtctcgtga tttgcgcgaa atcggcttga ccaaggtcaa gaaaaatgat
      181 atggtgtatt atgtactagt aaatgagaca gaaaagattg atttggtgga atttttgtct
      241 catcatttag aaggtgttgc aagagcagag tttaccttgg tgcttcatac caaattggga
      301 gaagcctctg ttttggcaaa tattgtagat gtaaacaagg atgaatggat tttaggaaca
      361 gttgctggtg ccaatacctt attggttatt tgtcgagatc agcacgttgc caaactcatg
      421 gaagatcgtt tgctagattt gatgaaagat aagtaaggtc ttgggagttg ctctcaagac
      481 ttatttttga aaaggagaga cagaaaatgg cgatagaaaa gctatcaccc ggcatgcaac
      541 agtatgtgga tattaaaaag caatatccag atgctttttt actctttcgg atgggtgatt
      601 tttatgaatt attttatgag gatgcggtca atgctgcgca gattctggaa atttccttaa
      661 cgagtcgcaa caagaatgcc gacaatccga tccctatggc gggtgttccc tatcattctg
      721 cccaacagta tatcgatgtc ttgattgagc agggttataa ggtggctatc gcagagcaga
      781 tggaagatcc taaacaagca gttggggttg ttaaacgaga ggttgttcag gtcattacgc
      841 cagggacagt ggtcgatagc agtaagccgg acagtcagaa taattttttg gttgccatag
      901 accgcgaagg caatcaattt ggtctagctt atatggattt ggtgacgggt gacttttatg
      961 tgacaggtct tttggatttc acgctggttt gtggggaaat ccgtaacctc aaggctcgag
     1021 aagtggtgtt gggttatgac ttgtctgagg aagaagaaca aatcctcagc cgccagatga
     1081 atctggtact ctcttatgaa aaagaaagct ttgaagacct tcatttattg gatttgcgat
     1141 tggcaacggt ggagcaaacg gcatctagta agctgctcca gtatgttcat cggactcaga
     1201 tgagggaatt gaaccacctc aaacctgtta tccgctacga aattaaggat ttcttgcaga
     1261 tggattatgc gaccaaggct agtctggatt tggttgagaa tgctcgctca ggtaagaaac
     1321 aaggcagtct tttctggctt ttggatgaaa ccaaaacggc tatggggatg cgtctcttgc
     1381 gttcttggat tcatcgcccc ttgattgata aggaacgaat cgtccaacgt caagaagtgg
     1441 tgcaggtctt tctcgaccat ttctttgagc gtagtgactt gacagacagt ctcaagggtg
     1501 tttatgacat tgagcgcttg gctagtcgtg tttcttttgg caaaaccaat ccaaaggatc
     1561 tcttgcagtt ggcgactacc ttgtctagtg tgccacggat tcgtgcgatt ttagaaggga
     1621 tggagcaacc tgctctagcc tatctcattg cacaactgga tgcaatccct gagttggaga
     1681 gtttgattag cgcagcgatt gctcctgaag ctcctcatgt gattacagat gggggaatta
     1741 tccggactgg atttgatgag actttagaca agtatcgttg cgttctcaga gaagggacta
     1801 gctggattgc tgagattgag gctaaggagc gagaaaactc tggtatcagc acgctcaaga
     1861 ttgactacaa taaaaaggat ggctactatt ttcatgtgac caattcgcaa ctgggaaatg
     1921 tgccagccca ctttttccgc aaggcgacgc tgaaaaactc agaacgcttt ggaaccgaag
     1981 aattagcccg tatcgaggga gatatgcttg aggcgcgtga ggagtcagcc aacctcgaat
     2041 acgaaatatt tatgcgcatt cgtgaagagg tcggcaagta catccagcgt ttacaagctc
     2101 tagcccaagg aattgcgacg gttgatgtct tacagagtct ggcggttgtg gctgaaaccc
     2161 agtatttgat tcgacctgag tttggtgacg attcacaaat tgatattcgg aaagggcgcc
     2221 atgctgtcgt tgaaaaggtt atgggggctc agacctatat tccaaatacg attcagatgg
     2281 cagaagatac cagtattcaa ctgattacag ggccaaacat gagtgggaag tctacctata
     2341 tgcgtcagtt agccatgacg gcggttatgg cccagctggg ttcctatgtt cctgctgaaa
     2401 gcgcccattt accgattttt gatgcgattt ttacccgtat cggagcagca gatgacttgg
     2461 tttcgggtca gtcaaccttt atggtggaga tgatggaggc caataatgcc atttcgcatg
     2521 cgaccaagaa ctctctcatt ctctttgatg aattgggacg tggaactgca acttatgacg
     2581 ggatggctct tgctcagtcc atcatcgaat atatccatga gcacatcgga gctaagaccc
     2641 tctttgcgac ccactaccat gagttgacta gtctggagtc tagtttacaa cacttggtca
     2701 atgtccacgt ggcaactttg gagcaggatg ggcaggtcac cttccttcac aagattgaac
     2761 cgggaccagc tgataaatcc tacggtatcc atgttgccaa gattgctggc ttgccagcag
     2821 accttttagc aagggcggat aagattttga ctcagctaga gaatcaagga acagagagtc
     2881 ctcctcccat gagacaaact agtgctgtca ctgaacagat ttcactcttt gatagggcag
     2941 aagagcatcc tatcctagca gaattagcta aactggatgt gtataatatg acacctatgc
     3001 aggttatgaa tgtcttagta gagttaaaac agaaactata aaaccaagac tcactagtta
     3061 atctagctgt atcaaggaga cttctttgac aattctccac ttttttgcta gaataacatc
     3121 acacaaacag aatgaaaagg agctgacgca ttgtcgctcc cttttgtcta ttttttaagg
     3181 agaaagtatg ctgattcaga aaataaaaac ctacaagtgg caggccctgg cttcgctcct
     3241 gatgacaggc ttgatggttg ctagttcact tctgcaaccg cgttatctgc aggaagtctt
     3301 aggcgccctc cttactggga aatatgaagc tatttatagt atcggggctt ggttgattgg
     3361 tgtggccgta gtcggtctag ttgctggtgg actcaatgtt gtcctcgcag cctatattgc
     3421 ccaaggagtt tcatccgacc ttcgggagga tgccttccgt aaaattcaaa ccttttctta
     3481 tgctgatatt gaacaattta atgcgggaaa tctagtcgtt cgaatgacaa atgatatcaa
     3541 ccagattcag aacgttgtca tgatgacctt ccaaattctt ttcagacttc ccctcttgtt
     3601 catcggttcg tttatcctag cggttcaaac cttaccttct ctgtggtggg tgattgttct
     3661 catggtagtc ttgatttttg gtttgactgc tgtcatgatg ggaatgatgg ggcctcgttt
     3721 tgctaaattt caaacccttc ttgagcgcat caatgccatt gccaaggaaa atttacgtgg
     3781 cgttcgtgtg gtcaagtcct ttgtccaaga aaaagagcaa tttgctaagt ttacagaggt
     3841 ctcaaacgag cttcttggtc aaaaccttta cattggttat gccttttcag tagtggaacc
     3901 ctttatgatg ttggttggtt acggggcggt cttcctctct atttggctgg tcgcgggaat
     3961 ggttcagtcg gatccgtctg ttgttggttc catcgcttct tttgttaatt acctaagcca
     4021 gattatcttt accattgtta tggttggatt tttgggaaat tctgtcagcc gtgccatgat
     4081 ttccatgcgt cgtattcgag aaattcttga cgcagagcca gctatgacct tcaaggatat
     4141 cccagatgaa gagttggttg gaagtcttag ctttgaaaat gtgaccttta cctatccaat
     4201 ggacaaggaa ccgatgctga aagatgtgag ctttactatt gaacctggtc aaatggttgg
     4261 tgtagttgga gcgactggtg caggaaagtc aaccttggct caattgattc cacgtctctt
     4321 tgatccacag gacggggcca ttaaaatcgg tggcaaggat attcgagaag tgagtgaagg
     4381 aaccctgcgt aaaacagttt ccatcgttct ccaacgtgcc attcttttta gtggaacgat
     4441 tgcagataac ttgagacagg ggaagggaaa tgctactcta tttgaaatgg agcgcgcagc
     4501 caatattgcc caggctagtg aattcattca tcgtatggag aaaacctttg aaagtccagt
     4561 tgaagaacgg ggaaccaatt tctctggtgg acaaaaacaa aggatgtcga ttgcgcgtgg
     4621 gattgtcagc aatccacgta ttctgatttt tgacgattcg acctcagcct tggatgccaa
     4681 atcagagcgc ttggtgcaag aagctttgaa taaggacttg aaggggacga caaccattat
     4741 tattgctcaa aaaattagct cggttgtcca tgcagacaag atcttggttc taaatcaagg
     4801 acgattgatt ggtcaaggca cgcatgcaga cttggttgcc aacaatgccg tttaccgtga
     4861 aatctatgaa acacagaaat gaaagacaaa ctataagaaa agtcaatagt tttatctaaa
     4921 ctatttctta tttcaatttg atgatttggc gatgatttta gagcacggca aaaagccctt
     4981 gaaaaagtcc attttttcaa aggtaatcct gtgttgattt cagaaattac atcacttttt
     5041 gttcgtcaaa tggcagctct tttttaggat ataaaacagg gttcggataa gtttttttgc
     5101 aaggtggatg atggctacat tgtaatgttt tccttgttct aacttagtct taaaagcagg
     5161 tgaaaagtga gggcatgctt tggcagcttg tatgagtacc taccgcagat gaggggaacc
     5221 ccgtttgacc attcttccag ctaaatcaat ctgacctgac tgataaatag aagaatccag
     5281 tccagcgaaa gcttgtaatt gagcaggatt atcaaaggca tgaatatttc gaatctcggc
     5341 taaaatgacc gcccctaaac gattctcaat cccagtaacc gtcgtgatga ccgagtttaa
     5401 ctcagccatc aagtcattga cacatttttc cgccttgtca atgagcctct tgtaatgttt
     5461 gatgttttca ttacacgaga taaaacgtct atgcgttatc aaactcatta ccaattaaaa
     5521 caaatgtggt tagatccttt cggaaattgt caagcgattg gaggaaatga actaatccac
     5581 agcggcttat tccaagtata ccacttgggc tttggcagta gctaactgcg ctaaatataa
     5641 tataaggagg agtaaaatga agacagttca atttttttgg cattatttta aggtctacaa
     5701 gttctcattt gtagttgtca tcctgatgat tgttctggcg acttttgccc aagccctctt
     5761 tccagtcttt tctggacaag cggtgacgca gctagccaat ttagttcaag cttatcaaaa
     5821 tggcaatcca gaacttgtat ggcaaagcct atcaggaatc atggtcaatc ttggcctgct
     5881 ggttttggtt ctatttatct ctagtgtaat atacatgtgt ctcatgacgc gcgtgattgc
     5941 agaatcgacc aacgagatgc gcaaaggtct ctttggtaag cttgctcagt tgacggtttc
     6001 tttctttgac cgtcgacaag atggcgatat cctgtctcat tttaccagtg atttggataa
     6061 tatcctccaa gcctttaacg aaagcttgat tcaggtcatg agcaatattg ttttatacat
     6121 tggtctgatt cttgtcatgt tttcgagaaa tgtgacgctg gctctcatca ccattgccag
     6181 caccccattg gctttcctta tgctgatttt catcgtgaaa atggcacgta aatacaccaa
     6241 cctccagcag aaagaggtag ggaagctcaa cgcctatatg gatgagagca tctcaggcca
     6301 aaaagccgtg attgtgcaag gaattcaaga ggatatgatg gcaggatttc ttgaacaaaa
     6361 tgagcgcgtg cgcaaggcaa cctttaaagg aagaatgttc tcaggaattc ttttccctgt
     6421 catgaatggg atgagcctga ttaatacagc catcgtcatc tttgctggtt cggctgtact
     6481 tttgaatgat aagtctattg aaacaagtac agccctaggt ttgattgtta tgtttgcaca
     6541 attttcacag cagtactacc agcctattat ccaagttgca gcgagttggg gaagccttca
     6601 gttggccttt actggagctg aacgaattca ggaaatgttt gatgcagagg aggaaatccg
     6661 acctgaaaag gctccaacct tcactaagtt gcaagaaagt gttgaaatca gtcatatcga
     6721 tttttcatac ttgcctgata aacctatttt gaaagatgtc agcatttctg cccctaaagg
     6781 ccagatgaca gcagttgttg ggccgacagg ttcaggaaaa acgactatta tgaacctcat
     6841 caatcgcttt tatgatgttg atgctggtgg tatttatttt gatggtaaag acattcgtgg
     6901 ctatgactta gatagtctta gaagcaaggt gggaattgta ttgcaagatt cggtcttgtt
     6961 tagcggaacg attcgagaca atatccgatt tggtgtgcca gatgctagtc aggaaatggt
     7021 tgaggtagca gcaaaagcaa cccacattca cgactatatc gaaagtttgc ctgataagta
     7081 cgatactctt attgatgatg accagagcat cttttcaaca gggcagaagc aattgatttc
     7141 aatcgctcga accctgatga cagatccaga agttctcatt ctcgatgaag caacttcaaa
     7201 cgtagatacg gtgacagaaa gcaagattca gcatgccatg gaggtggttg tagcaggtag
     7261 aactagtttc gtcattgccc accgcttgaa aaccattctc aatgcagatc agattattgt
     7321 ccttaaagat ggagaagtca ttgaacgtgg taaccaccat gaacttttga agctaggtgg
     7381 cttttattca gaactctatc acaatcaatt tgttttcgaa taagaaagaa gttgtcctat
     7441 gtgggcagct ttttcttgtc cataaaaaat gtttatcaca gccttaaaaa aaacatatta
     7501 gacgaaagtc attttgagtg atatgatagg actatcgtta gcattcgaaa ggagaggcat
     7561 catggctaga acggttgtag gagttgctgc aaatctatgt cccgtagacg cagaaggcaa
     7621 aatcattcat tcatctgtat cttgtagatt cgcagagatc attcgtcaag tcggtggtct
     7681 ccctttagtc attcctgttg gtgatgagtc agttgtacgt gattatgtgg aaatgattga
     7741 caaactcatt ttgacaggag gccaaaatgt tcatcctcag ttttatggag agaaaaagac
     7801 cgtcgagagc gatgattaca atctggtccg tgacgaattt gaattggcac tcttgaagga
     7861 agcgcttcgt cagaataaac caattatggc aatctgtcgc ggtgtccaac ttgtcaatgt
     7921 tgcctttggt ggaaccctca atcaagaaat cgaaggtcac tggcaaggac tacctttcgg
     7981 gacatctcac tctattgaga cagtagaagg aagcgtggtg gctaagctct ttgggaaaga
     8041 aagtcaggtc aactcagtcc atcgtcaaag cattaaagat ttggcaccta atttccgtgt
     8101 aactgctatt gattcaagag accaaactat tgaagcgatt gagtctatcg acgagcaccg
     8161 cattatcggt ttacagtggc atccagagtt tctggttaat gaagaagatg gcaatttaga
     8221 attatttgag tatttattga atgaactgta
//
LOCUS       DAVKBC010000062         8073 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVKBC010000062 DAVKBC010000000
VERSION     DAVKBC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.062"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..532
                     /locus_tag="VWX64_001858"
                     /pseudo
     CDS             1..532
                     /locus_tag="VWX64_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1270..1530)
                     /locus_tag="VWX64_001859"
     CDS             complement(1270..1530)
                     /locus_tag="VWX64_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191274.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1589..2140)
                     /locus_tag="VWX64_001860"
     CDS             complement(1589..2140)
                     /locus_tag="VWX64_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191275.1"
                     /translation="MPANTKVIFQETFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYTLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(2130..3125)
                     /locus_tag="VWX64_001861"
     CDS             complement(2130..3125)
                     /locus_tag="VWX64_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191276.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLSISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHILKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(3533..3958)
                     /locus_tag="VWX64_001862"
     CDS             complement(3533..3958)
                     /locus_tag="VWX64_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191277.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(4087..4445)
                     /locus_tag="VWX64_001863"
                     /pseudo
     CDS             complement(4087..4445)
                     /locus_tag="VWX64_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835110.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4491..4697)
                     /locus_tag="VWX64_001864"
     CDS             complement(4491..4697)
                     /locus_tag="VWX64_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191278.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTHFSLIAVNSDMPLGR"
     gene            complement(4684..4845)
                     /locus_tag="VWX64_001865"
     CDS             complement(4684..4845)
                     /locus_tag="VWX64_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9191279.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(5236..6192)
                     /gene="lytA"
                     /locus_tag="VWX64_001866"
     CDS             complement(5236..6192)
                     /gene="lytA"
                     /locus_tag="VWX64_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU9191280.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(6568..7938)
                     /locus_tag="VWX64_001867"
     CDS             complement(6568..7938)
                     /locus_tag="VWX64_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9191281.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLDQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILLQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIAQGLRIGSRLSISWAVFVCIF
                     LFFASPALISFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
BASE COUNT         2612 a         1642 c         1291 g         2528 t
ORIGIN      
        1 actcttgttc aaagtggttt tacgatttca agaactcctc tcagttctga ggacacggta
       61 atgattgatg cgacggaagt aaaaatcaat cgccctaaaa aaagaattag cgaatgattc
      121 tggtaaaaag aaatgccacg ctatgaaggc tcaagcgatt gtcacaagtc aagggagaat
      181 tgtttctttg gatatcactg tgaactattg tcatgatatg aagttgttca aaatgagtcg
      241 cagaaatatc ggacaagctg gtaaaatctt ggctgacagt gattatcaag ggcccatgaa
      301 gatatatcct caagcacaaa ctccacgtaa atccagcaaa ctcaagccgc taacagctga
      361 agataaagcc tgtaaccatg cgctatccaa ggaaagaagc aaggttgaga acatctttgc
      421 caaagtaaaa acgtttaaaa tgttttcaac aacctatcga aatcatcgta aacgctttgg
      481 attacgaatg aatttgattg ctggtattat caatcatgaa ctaggattct agttttgcag
      541 gaagtctatt atatatgcac agacatatga aatctttttg agacagcagt tatgatatat
      601 ttatccattc acaacatctt ctgtactaat actacaatat tggtacattt tgattacaca
      661 atcgtttcaa aaaatatgat ggaagcctga gtattttata gtaattccct tcctatcaac
      721 tagatcaacc agttgagtgt tgaatgttga aacaccctag cctcagcaaa ggactatgat
      781 cagcatttcc tagccaatag gacgctccaa atcacctatt ctaagtccat cactagcttg
      841 gtcagtaaga tacagactgc aaggcgagac tgatgtggtt gatgagattt tggaagagta
      901 ttacaatcat agattcacca gtagacttga ccgcagattt aactatagta gattgaaact
      961 agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgactg tcctgatcaa
     1021 tttgtcctgt tctcgtttca ttttactata ctaaaaaacc acctgaaaca aatcaagtga
     1081 ctagaggata aaaacaaaaa ctgggcaaaa agttttgaaa agcaaaaaac gcataatatc
     1141 aggtcttgaa aaaccttgat actatacgtt tgattgtggg aagattgact tcattttctc
     1201 ctgaaattga agttttttct agtttccaga tataaacgaa ttcaatatag ccatctcgct
     1261 acaattattt taaccatcga gaaaattttt cagaatttca aaaatttcat tttgatccaa
     1321 tgaaatgtca tcattttgaa gaatagttga cttcacaggc tctaattcta tcacaaagcg
     1381 gtgcatgtct gcttttaccg cactacttga tgttatagcc gataactttt catctcctag
     1441 caaggaagct gtcaaacggg taatgtcatt caaatgcttt ttaatggact tacttaaatc
     1501 ttgagcacct gtagcagagc gctctctcat atccagccaa gctttagcct taaaaataat
     1561 taatactcaa tgaaaatcaa agagcaaact aggaagctag ctgcaggctg ctcaaaacac
     1621 tgttttgagg ctgtagatgg aagctgacgt ggtttgaaga gattttcgaa gagtatagac
     1681 cacaattact caataccgaa tacccctgaa tggtttcttt ttcatgcacc aatatattat
     1741 aataatcttc atccaataat aaggctgata aactagcatc ttggtcaaaa tgtaagggaa
     1801 tttctcggcc gtccttcttt aatgtatatt ctggtaagat actaaatagt tcaatcatag
     1861 aaggaaactc aggattagtt gttgtaaatc gaaaaagctg cgctttctca tctttctgac
     1921 ttccttgata ctctcccaat tctaaaaaat gattcaaggt agtataaaat tccttatttt
     1981 ttacttcatc aatgatgacc atatcataat cttttgttgt gcgactttta aatccttgcg
     2041 aatccaatac gatagaggta gcagttcccc caatcagaac ataatagttc tgaaaatccg
     2101 caaacgtttc ttgaaaaata actttcgtat tagctggcat catcttctcc cagatactgt
     2161 aatatcatat tttctagtgc ttcactctct tcctctatac gtgggtcatc atcatctttt
     2221 aaggtcaaat aaagagaaat cggatctaca aattgtttat catgattatt tttaaaatca
     2281 ttccaaaact cagatacaaa aggacgatat ttccatatct ctagcatctt tccttttaaa
     2341 atatgctgag aaagtggcaa ggataactga ttgaattttc tctgccatat gacatagcta
     2401 gtattttcat ccgtttcagc taaaaaagtt gaatgcgaca aagcataagc accaccatat
     2461 agaaggttag aaacagattt tatctgcttt atatcgccat ctggcaataa aatccgtttt
     2521 ttgatgggat taaataaaca tgacacggat tttaagaata attctttctt tgacaccgta
     2581 tatgtgtaaa gcttattttg cttgtttaac caatataaag ctttaaaagt cctcaaacac
     2641 ctataaattg ttgagtttgg aagtccagtg acttgtgaaa gcaaatcaac atctactact
     2701 ttttgacctt ttgtcaataa aaaggcaatc cacgttaatt gttcgctagg tgttaattcc
     2761 ttagggactt cagtatcatt cgcattgagt actagtccca atggagggaa gaagaggttt
     2821 cccttaaagt ctacaaacgg aactctagct tgaagtaatt gctttttttc actgtctgat
     2881 aacttcgaaa acaccaaaac aacatccata ttggcttttt cacccatagt gcgagcctga
     2941 gtaacaaatg aactcaaact cccccttctc ttttctttaa tcaataaaaa tgattcctta
     3001 tgaaaagtca tttgagtata ctcaaacctt tttacaaaac tgattgataa agtcaaagtc
     3061 agttcctcaa tactgacatc aacataaaag gattgaaaaa ttgacattat ctttttgaca
     3121 ttcatgtttt ttccttattc tatcattttt attatatttt atcattcggt ataataaaat
     3181 ataagttttt tgataaaata accaaaaact actccctatc ccctctcaca ctaccctaca
     3241 tatcgtttga catgcgactg atagttcagg aaaacttcaa ggagaacttt tctctcatcc
     3301 actatgcagg acttactatt tcacttctac tcctataggc tcaatttgac acttttcttt
     3361 ttcgaattgc tcatatgcct cctgaatagt gagttcgatt tatccaaatt tatttttgtc
     3421 tattttgatg aatacttcca cgaagatagt ctgaaaatga atttgcacca attttccttc
     3481 tctttttaag catattattc cagatatgat tgccctcttg ttcagtaata aattacgctt
     3541 taaacgcttc aatcagtata tctcctgttg tcatatgttc taaagaaaat tcttctacat
     3601 atgatttaac atctcttagg ttattacttc ctaatatccc attatgcttt ttcgctaagg
     3661 aaatagaagc cgcttctccc ttaccaataa tcttgttact atcatgattt cttgttaaat
     3721 ctctatataa tgcgtattct tcagttccaa tgtctatgct cacaatctca gctgaaccct
     3781 tagctaccaa ctgatctatc ctagatttta aatggggaat tgtaggtata ttgatttcat
     3841 catacacctc ttgtggaata acaattttac ccgaatagag cttttctaaa agatgttcag
     3901 taccaaccca taaaaatact gaaatacaat ctgcatcaat aaatacacga ctagtcaaac
     3961 gacaactccc ccctcttcat ctagcccata tacaatatca tatctgaaag catctagtaa
     4021 cagttcctca tacttccctt gcgaaattct gctattttct aaaagttgtt cagtcaaatt
     4081 aatatattat actaatacca tttccttttt actttctgac aaaggacgat ataaacttgt
     4141 atcatagcct aatcttgaag ctgtctctat aacactaata tccatatttt taatttcttc
     4201 tgcatcaagg tatccatcat tcctcaatct atataacata gctttatgac tgataccata
     4261 aaactgaccc aattttataa tatcttctac ttcaagatga gttctattgg cattttctct
     4321 gatttcctca accatcctat acagtgaaat gggaaaatta aaaaataaga agcaaactga
     4381 tccgcttttc tttcagtttc atctccttca ccaatcaaga taagactgac tgaactcttc
     4441 ttcacctcat cataataaag atgatacagt tcatgtgcta aagaaaatct ttaccttcct
     4501 aatggcatgt ctgaattgac tgcaatgaga ctgaaatgag ttcctttata acagactccg
     4561 ctaatattct ttccgagtcc ataaaatacc agcgtcaaat tttctatctt ttgtaccaat
     4621 ttaaaaatat ctatcggcga ttcaccatca gctcccaact tttttctaag atttggagct
     4681 ttattactta aatccattcg tgatattcct ttcacctttt tccattttgg caatcatgct
     4741 ttgattcaaa gacaaatact cagcaatctt atcttgagta agatttgaag atattctaag
     4801 ttcttttatt ctttttccaa catcacatac atttatcata ttcatttatc atattcattt
     4861 atcatattca tacacctctc ataaaaagaa tagcacactc ttgtcataat tttttaaata
     4921 aaaaaattat gacaaaacaa ggaagcaatt tattgatgct gcttaaaaat ctaaaattga
     4981 tgatattaaa cctatttgat gaattcctat caaaaatcgt atcttcaacc tcaaaacagt
     5041 acttaaagct atccgactcg gtttacattg tcaaatttag attttatttg agcataactt
     5101 tctagtttgc tttttgattt ttgtttaata tagtagcaaa aattgaagga aatatctcca
     5161 caagaaaacg catactatta agctttttca agacctaata atatgcgctg ttctgatttg
     5221 aaagacattc cattattatt ttactgtaat caagccatct ggctctactg tgaattctgg
     5281 cttgtctgcc agtgttccgt ctggtttgag gtagtaccag cctgttccgt ccgctgactg
     5341 gataaaggca tttgatacca tggcgccttc tttagcgtct aagtagtacc aagtgtcctt
     5401 gtacttgacc cagcctgtct tcatggcacc ttcttcgttg aaatagtacc acttatcagc
     5461 gattttcttc cagcctgtag ccatttcgcc tgagttgtcg aaccagtacc agttgccgtc
     5521 tgtgtgcttc ctccagcggt ctgcaagcat atagcctgaa ctgtcaaagt agtaccaagt
     5581 gccattgatt ttctcaaact tgtcttttgg ataagagccg tctgagtgta cgtaccagta
     5641 gccagtgtca ttcttctgcc agcctgtttc aatcgtcaag ccgttctcaa tatcatgctt
     5701 aaactgctca cggctaatgc cccattttgc caagtaaggg tatggatcca catggtctga
     5761 gtggttgttt ggttggttat tcgtgcaata ctcgtgcgtt ttaattccag ctaaactccc
     5821 tgtatcaagc gttttcggca aacctgcttc atctgctaga ttgcgtaaga gttcgatata
     5881 aaggcggtag tccgtcatga actcttcttt agttgaatgg ctttcaatca gttcaaccgc
     5941 tgcataggtc tcagcattcc aaccgccccc aacgtcccag gcaccattat caacaggtcc
     6001 tacctgcatg atgcaaccgt tcccaacaat gtgcgagaaa aaacctaatt ctgggtcttt
     6061 ccgccagtga taatccgctt cattctgtac ggttgaatgc ggattcccag ttgagtgtgc
     6121 gtgtacttgc ctatatggtt gcacgccgac ttgaggcaaa tctgttctta atttactcac
     6181 attaatttcc atattctact ccttatcaat taaaacaact cattttttac aatccaaaac
     6241 cagaaactcc tttatttcta ccttacaaag aagacaatct tagtcacgat taggcttgta
     6301 gatagaacct caaaacgcac tattttgaca ctgtaaatag gactgacaag gtctgcattc
     6361 tatctacaat aacaccccag actaaaaagc ttttcaaaag tatattttta cagtctctat
     6421 atgtcctttt cataaatact atactttatt atatcatata aaagaagtca aaagtctgtt
     6481 aaactatttt caacaccaaa ctaaagaaga gaacacaagt tttttcgatg ttcactagag
     6541 gaaatggatt ttattcagta aatccaacta ggattgcact ttggttgcca aaattgcctt
     6601 tccttctttt atcaagggat gacggaatag tgagaagtac agttgaactg tcatggcaac
     6661 ccagataaga ggttcacaaa ggataacacc cttatatcct gcccaaggaa taatcaaaac
     6721 cacaaaaacg atttttccga ttagttcaat aaagctagaa actagaggaa ggatcttctg
     6781 ccccaagccc tgcaagcaat tgcgataaat caacaagagg ctcaaaatgg gataaaaggc
     6841 tgaactgatt tgcagataga gacttccatt ttctatcaag taaccatctg tcgaactagc
     6901 caagaaggaa atcaaggctg ggctggcaaa aaagaggaaa atacaaacaa aaactgccca
     6961 ggatatactt aaacgactgc cgattcgaag accttgagca atgcggtcag gtcgcttagc
     7021 tcctagattc tgagaagcaa aggtcgtcat tgatgcagaa atagcggtca taggaagaag
     7081 ggcaaaggtc ataatgcgtc gagctgccgt ctgggcacta ataatcactg caccaaatgt
     7141 attaacagaa gactgtaaaa tcacactgcc gatagataca attgaactca tcaagcccat
     7201 agccaaacct tgctccaaga gatccgcgta caagcttttg tcccatttga aatgtttaaa
     7261 ctgtggcaag agttctggca cacttttacg aatataataa aagcagagaa ccgctgataa
     7321 accttgtgaa ataatggtag caagtcctgc ggattgaact cccagatgca attgcgtaat
     7381 aaaatagaga tccagaacca cattaaccaa ggcagagaaa atcagaaatc ccagggctgc
     7441 tagactgtca ccaatagacc gcaacaagcc tgcaaaaaga ttataagcaa agctgacacc
     7501 tacacaggtc acaatcatag aaatatattg ataagattga agaagaattt ctgcaggagt
     7561 atctaagtat tgcaagagag gatacaagcc aagaaagccc agtaacataa ctagaatgct
     7621 caaaagagca cctaaaatcc aggtggctgc tactgcttcc ttgattttag tgaaattccg
     7681 agccccataa taacgagcaa tgacaatccc catgccattg ccaacaccaa gtgtaaaacc
     7741 tacaatcagg tcaaaaatcg ctgtcgtcgc tcctactgca gccaaggatt cttgatcaag
     7801 aaatcgtcca acaatcaaga catcagcagt gttatagagc tgttgaaaaa tatttgatag
     7861 caagattgga aaggtgaagc ttaagagcga gggaagaatc ggaccatgta tcaggtccac
     7921 tgttcgtttt ttattcataa agctattata tcagctttcc agaggagcga caagaaacag
     7981 caaacttata tatagcggaa tgaaataagg aaagtcaaat cgatttttaa caatgtttta
     8041 gaagtagatg tgtactattc tagtttcgat cta
//
LOCUS       DAVKBC010000063         7870 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVKBC010000063 DAVKBC010000000
VERSION     DAVKBC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7870
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.063"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..63
                     /locus_tag="VWX64_001868"
     CDS             <1..63
                     /locus_tag="VWX64_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylase"
                     /protein_id="HEU9191282.1"
                     /translation="VVDHFELTIEKWLSKSQQLL"
     gene            complement(578..1570)
                     /locus_tag="VWX64_001869"
     CDS             complement(578..1570)
                     /locus_tag="VWX64_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9191283.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1730..3484
                     /locus_tag="VWX64_001870"
     CDS             1730..3484
                     /locus_tag="VWX64_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191284.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            3468..5189
                     /locus_tag="VWX64_001871"
     CDS             3468..5189
                     /locus_tag="VWX64_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191285.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     EDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            5200..5784
                     /locus_tag="VWX64_001872"
     CDS             5200..5784
                     /locus_tag="VWX64_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9191286.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            5784..6479
                     /locus_tag="VWX64_001873"
     CDS             5784..6479
                     /locus_tag="VWX64_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9191287.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAILCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            6467..7831
                     /locus_tag="VWX64_001874"
     CDS             6467..7831
                     /locus_tag="VWX64_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191288.1"
                     /translation="MVEIKNLSLDYGEKHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFKDEVFNELRLGVKNFDEEKAKIILKDLCLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         2842 a         1064 c         1366 g         2598 t
ORIGIN      
        1 gtagttgacc attttgaact tacaatcgaa aaatggttaa gtaaaagtca acagttacta
       61 tagtttgcaa attatttaca gaaagaacaa aaaatgctct gaaacactga tttcaaagca
      121 ttttttgtta gtttaaaatt actcccattc ttcttttcca aacgtacaat atatccaaaa
      181 ccattcaaaa tactagattc tattttttat aatatcacta aatccaccta attataggac
      241 gttttcagat ttttagtccc gtcccagtcc cagtaccgga gaaatattgt tttaatataa
      301 tatctctttt tgtcttctaa gctcttaaaa gcaaaagaac aagtaaagag tcaagacaag
      361 gataaaaagt ccatattagg gcaaataaaa agctttaaga cagatgacaa atctaagtca
      421 aataagaaag accatagcaa aggtgcagag agataaatat tggcggtctt cggactgcct
      481 ttattttttt atccattttt caaatcaaat ttattcagac tatatatgca catatacact
      541 taaattcata taaaaacatg gcttgtaaaa aattacttta atcacaataa tcgcatttaa
      601 aattgtgatg tttgcaagct aaattacgga cttcacttgg aagttttccc ttgtatcttt
      661 tataatagat agaaaatttg ctggcagatg aatatccaac agattctgct atctctttta
      721 taggtagttc agtgtttaaa agaagagttt cagctacatt cattcttttt ctttgagtgt
      781 actctgtaat gctttgacaa tatttttcct taaataaatt ttttaattta gtaccactca
      841 ttttagatat tttttcaagc gtgccttgat ttacattcgt tgcaaaatga tcatctaaga
      901 atcttgctac atcttcaagt gctttatcat catcaatttc aattttatat ttttttctat
      961 ttaagtatgt gtcaattact atacttatcc attcatttgc ctttgcttta aagaaaaaat
     1021 cagcggcagg agcgtccatc ttacaattta atatttccat tgccactctt tctaaggcct
     1081 ttgtaagtat tatttgattc ggttgaagca aggttgaata aaaagattct ggattaatgt
     1141 taatagatgc taaatgtttt tctattagct cttttttaaa accaatggaa acagcaagat
     1201 aacaacaatt ctcgtgtaat aaaaaaacaa aatcatcttt tatattatca aaatcaaaag
     1261 tacataaaga gtttgcggta atagtttgat acggattaaa cttttctccg tttgcactga
     1321 caatataact tgaataaatt gaaacatagt ctgacatact ataagtgcta ttttgaacta
     1381 cttcctcttt gatataaaaa tcatgtatat cgataatgaa gctgcctcct tcataaaacc
     1441 aatataggcc ttctgcataa gttgaattct cttttttcca acaaaatgta tgacctgcac
     1501 ttgaatactt ctcattgttt ttacattcat ctactttcat ataatctttt acaaaatcat
     1561 aatatgacat aacacactat cccttttaga caatattcca attagcctta ttaattcaaa
     1621 actattgtat tagtaattat aacagatgta taatagaaaa gcaatgatag atattatcaa
     1681 ttaagcgaat ttatatctaa aagggatatt aaagaaagga gatatgctta tgaagattta
     1741 caaaaaacta tttgcttatg tccaagataa gaaatatctt ggggttttgg ccataatttt
     1801 ttctgctata tctgctgcac ttacagtata tggatattat ttaatctaca aatttctaga
     1861 taagttaata attaattcaa acttatccgg tgcagagagt atagcattaa aatctgttat
     1921 tacactaaca agtggagcga tattttattt tgtctcagga atgttttcac atatcttggg
     1981 atttaggctt gaaacaaatt taagaaaaag gggaatcgat ggtctggaaa aagcaagttt
     2041 taggttcttt gacttaaatc catctggtca aataagaaag atcatagatg ataatgcagc
     2101 acaaactcat caggtggtag ctcacatgat tccagatagc tctcaggcaa tagtcacacc
     2161 tatacttgtc cttgtactag gctttatagt aagtataaga gttggcataa ttttgcttgc
     2221 tcttactata attggtggct taattttagg ggcaatgatg ggcgagcaag aatttatgaa
     2281 gatataccaa gaatccctat ctaaactaag tgctgaaact gttgagtacg tgagaggaat
     2341 gcaagttgta aaaatattta aagcaaatgt agagtcattt aaaagctttt acaaggctat
     2401 aaaagattac tcaaagtatg cttatgatta ttccctatct tgtaaaaggc cttatgtttt
     2461 gtatcaatgg ttattttttg gactgattgc aattttaatt attcctatag tttattttat
     2521 gactagctta gctagcgcaa aggtgatttt acttgagctt atcatgattt tatttttatc
     2581 aggagttctc tttgtttcat tcatgagaat gatgtggtac tccatgtata tttctcaagg
     2641 aaattatgca gtagatactt tagaggcgct ttacgaagat atgcaaaaag acaaattagt
     2701 gcatggtaat gtcaataatt ttaaaaacta taatatagaa tttgagaatg ttagctttgc
     2761 ttataatgat aaagctgtca ttgaaaattt atcctttaat ttagaagaag gaaagtccta
     2821 cgcacttgtc ggttcatctg gatcaggcaa atcaacagta gcaaaactta tatcaggttt
     2881 ttacaatgtt aatgaaggaa gcataaagat aggcgggata gcaataagtg aatattctga
     2941 cgaagcctta attaaagcca tttcctttgt ttttcaagat tcaaaattat tcaagaagag
     3001 catttatgat aatgtagctt tagctaataa agatgcgacg aaagatgacg ttatgagagc
     3061 cttaaaatta gcaggatgcg atttaatatt agacaaattc ccagaaagag aaaatacaat
     3121 cataggctca aaaggtgttt atttatccgg tggagaaaaa caaagaattg caattgctag
     3181 agcaatttta aaggattcca aaattattat tatggatgaa gcatcagcat ctattgaccc
     3241 agataatgag tttgaattgc aaaaagcttt taaaaatctt atgaaggata aaacagttat
     3301 catgattgca cacaggctat ctacaattaa agaccttgat gaaattattg tcatggatag
     3361 tggaaaaatt atagaaagag ggtctgacaa agaattaatg tcaaaagata caaggtataa
     3421 gagcctgcaa gagatgttta acagtgcgaa tgaatggagg gtttcaaatg aaagagtttt
     3481 ataaaaaaag atttgctctt acagatggag gagcaagaaa tttaagtaaa gcaacactgg
     3541 cttcattttt cgtttattgt ataaacatgc ttcctgccat attacttatg atttttgctc
     3601 aggaagtttt ggaaaatatg ggcaaaagca atggctttta tatagtattc tcagttttga
     3661 ctttgatagc aatgtatatt ttgctttcta tcgaatacga taaattatat aacacaacct
     3721 atcaagaaag tgcagattta agaataagga cagcggagaa tttatcaaaa ttacctctat
     3781 cttacttttc taaacatgac atttccgaca tttcacaaac aatcatggct gatattgaag
     3841 gcatagagca tgcaatgagc cactcaatac caaaggtggg cggcatggta ctgtttttcc
     3901 cattaatatc tgtaatgatg ctagcgggca atgtcaagat gggtttagct gtaattattc
     3961 catctatttt aagctttata tttatacctt tatctaaaaa atatcaggtt aatggacaga
     4021 atagatatta tgatgtctta agaaaaaact cagaaagctt tcaagaaaat atcgaaatgc
     4081 aaatggagat taaagcatat aatttatcga aggatattaa agaagactta tataaaaaaa
     4141 tggaagatag tgagagagta cacttaaagg cagaagtaac tacaatttta actttgtcta
     4201 tatcttcaat atttagcttt atatctcttg ctgttgtgat atttgtcggc gtaaatctaa
     4261 ttattaataa agagataaat tctctctacc ttataggata tttactagct gctatgaaga
     4321 taaaagactc tttagatgca tctaaagagg gcttgatgga aatattttat ttatcgccca
     4381 aaatagaaag attaaaagaa attcaaaatc aagatttaca agaaggcgat gactatagct
     4441 taaaaaaatt tgatattgat ctaaaagatg ttgagtttgc ctacaataaa gacgcaaaag
     4501 ttttaaatgg tgtaagtttt aaagctaagc agggagaggt cactgctttg gtaggtgcaa
     4561 gtggctgcgg taaaacaact atcttgaaac ttatatcaag actttatgat tatgacaagg
     4621 gacaaatctt aatcgatggc aaagatataa aagaaatatc aacagaatct ctttttgata
     4681 aggtctctat agttttccaa gatgtggttc tctttaatca aagcattatg gaaaatatta
     4741 gaatcggaaa gcaagatgca agtgacgaag aggttaaaag agcagcaaaa cttgcaaatt
     4801 gcacagattt tatagaaaaa atggataaag gtttcgatac agttattggt gagaacggag
     4861 ctgagctatc aggaggagaa agacaaagat tatcaatagc cagagccttc ttaaaagatg
     4921 cgccgatatt gatcttagat gagataacag caagccttga tgttaacaac gagaaaaaga
     4981 ttcaagagtc tttaaataat ttagttaaag ataaaactgt tgtaatcatt tcacatagaa
     5041 tgaaatccat agaaaatgca gacaagatag tagttcttca aaacggaaga gtagaaagcg
     5101 aaggtaagca tgaagagctt ttacaaaaat caaaaattta caaaaattta atagaaaaga
     5161 caaaaatggc agaagaattt atttattagg aggactacaa tggataataa aaaattaaaa
     5221 gtaaaagatt tagtaagtat cggtgttttt ggcgtaattt attttgcctt catgtttgga
     5281 gttggtatga tgggcttgat tccaatattg ttcttaatat acccgacagt attagccata
     5341 gttgcaggaa ctgttgttat gttatttatg gctaaggttc aaaagccatg ggcactattt
     5401 atatttggta tgatatcacc acttgtgatg tttgcagctg gtcataccta cgtagttgtg
     5461 gttttatcac ttatagtaat gataatagca gaattaatta gaaagattgg taattataat
     5521 tcatttaaat acaatatgct ttcttatgca atcttcagca catggatatg tagctcttta
     5581 atgcaaatgc ttttagcaaa agaaaaatat atggagtggt ctttgatgac gatgggaaaa
     5641 gattatgttg atgtattaga aaagttaata acttatcctc acatggcttt agtagcctta
     5701 ggtgctttct taggaggaat tcttggagca tatataggca aggctctatt gaaaaaacac
     5761 tttgaaaaag caggcatcgt ataatgccta ctttttcttc aaatgctccc tttaatccca
     5821 atccgatctc taagatatta gtcgtattta tcacaggctt aactgttatg catagcataa
     5881 acatccgttt tgagctggca attctttgtc ttattggtat tttgctttat ttgaatggat
     5941 acaaaaaaac acttttcaaa tggattatat tgtgtgggat actttactcc ttgcctaatt
     6001 ttatggtgtt atctgaatta aaccctatag ttaagatgtt tttgagtata cctattgtta
     6061 ttagaatgtt tattttacca tttatggcag caagctttat gataaagacc tcggatgtag
     6121 gcgcaataat ttcatcgatg gataagctta agatttcaaa gaatgtatcc atacctattg
     6181 cggttatgtt tagattcttc ccatctttta aggaggagaa gaaaaacatc aaaatggcta
     6241 tgagagtaag agggataaat tttaaaaacc cagtcaaata tcttgaatat gtttctgtac
     6301 cactactcat tatatcatct aatatatcag atgacattgc aaaagcggca gaaacaaagg
     6361 caatagaaaa tccaattgct aagaccagat acattcgcgt aaagatacag ctaattgatt
     6421 ttgtttatgt tttagcggtt gctggactta ttgtgggagg cttaatatgg ttgaaataaa
     6481 aaatttaagt cttgattatg gtgaaaagca tatattagat gatatatcac tatccatagc
     6541 cgagggagag tgcgtgctat ttacaggaaa aagtggaaat ggtaagtcat ctttaataaa
     6601 ttcaatcaat ggactagctg taaggtatga taacgcaaag acaaagggcg aaataattat
     6661 tgatggtaag aatataaaaa atttggaact ttatcaaatc tcaatgcttg tttcaactgt
     6721 ttttcaaaat cctaagacat atttttttaa tgtcaatacg acattagaat tattatttta
     6781 tttggaaaat atcggtcttg caagagaaga gatggacagg cgtttgaagg atatacttga
     6841 gatattcccg ataaaaaatc ttttgaacag aaatatattt aatctatccg gcggtgaaaa
     6901 acaaattctt tgcattgcag cttcttatat agcaggtaca aagattatag ttatggatga
     6961 gccttcatcg aatttagata ttaaaagcat aagtgttttg gcaaagatgc taaagatatt
     7021 aaaagagaaa ggcataagca taattgttgc agagcataga atttattatt tgatggacat
     7081 agttgaccgt gtatttttaa tagataaagg aaagcttaaa aaaacttata ctagaagtga
     7141 atttttaaag ctagataaaa atgaattaaa tgctttaagt ttaagagata aagaattaag
     7201 taaattaaaa gttccttatt taaaagaagg tggagagtat cagataaaaa atcttagcta
     7261 caaatttact gatgatgagt gtttaagctt aaaagatatt tcgttcaagc ttgggaaaat
     7321 ttatggcata ataggatcca acggacgagg aaaatcaacg cttttaagat gtttaatagg
     7381 tcttgagaaa aaatcaaaag aagaaattta ttttaaggga gagaagctat ctaaaaaaga
     7441 aagactcaaa aactcttcac ttgttatgca agatgtaaat catcaattat tcaaagatga
     7501 agtattcaac gagcttagat taggagtaaa gaattttgat gaagaaaagg cgaaaatcat
     7561 tttaaaagat ttatgcctgg acgaatttat tgaaaggcat ccgatgagtt tatcaggagg
     7621 gcaaaagcaa aggcttgcaa tagcatctgt tatgtgcaag aattctccat ttgtcttttt
     7681 tgacgaacct tcaagtggta tggattattc caatatgata aaaatatctg aactgattaa
     7741 taagtataaa accatggata aaataatttt tattgtttcc catgatatag aatttttaaa
     7801 tgaagtggca gatgaaattt ttgaattgta aaatagagtc tgttaaacat gtctatagaa
     7861 ctggtaaatt
//
LOCUS       DAVKBC010000064         7639 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVKBC010000064 DAVKBC010000000
VERSION     DAVKBC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.064"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..780
                     /locus_tag="VWX64_001875"
     CDS             <1..780
                     /locus_tag="VWX64_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9191289.1"
                     /translation="DAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSK
                     LILRRQEQLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEE
                     YCLFLNTKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDEL
                     IKYKHLRINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILL
                     PLPPLALQNEFADFVALVDKSQFACEIAIKVWRNSLKFSII"
     gene            885..4161
                     /locus_tag="VWX64_001876"
                     /pseudo
     CDS             885..4161
                     /locus_tag="VWX64_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562199.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            4432..4632
                     /locus_tag="VWX64_001877"
     CDS             4432..4632
                     /locus_tag="VWX64_001877"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191290.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(4726..5196)
                     /locus_tag="VWX64_001878"
     CDS             complement(4726..5196)
                     /locus_tag="VWX64_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9191291.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(5213..7486)
                     /locus_tag="VWX64_001879"
     CDS             complement(5213..7486)
                     /locus_tag="VWX64_001879"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU9191292.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         2408 a         1264 c         1623 g         2344 t
ORIGIN      
        1 gatgctgtaa aacatactca tggttccaca atgaaacatt taactaaaaa atattttgat
       61 aatattatag ttccatatac aaatttggga gagcaacaaa gaattgcaag tgagctggat
      121 ttgttaagca agctgatttt aaggagacaa gaacaacttg aagagcttaa tctacttgta
      181 aaatcccgat ttaacgagat gtttggggaa aataaaatat ttgaaagcat tgataactta
      241 tttgatatta tagatggtga taggggcaaa aattatccta aatcagatga gttgtttagt
      301 gaggagtact gtttattttt aaatacaaag aatgttacta aaaacggatt ttcattcgat
      361 acaaagcaat ttatcactaa aacaaaggat aaattacttc gaaaaggcaa acttgagcgt
      421 tatgatatag tcttgacaac aagaggtact gttggaaatg tagcgtacta cgatgaatta
      481 ataaaatata aacatttacg tataaattca ggtatggtaa tattacgtcc caagacacca
      541 aatctaaatc agaaatttat tatccatgtt ttaaggaata ataattatag tcgagtgata
      601 tcaggaagtg ctcagcctca gttaccaatt acaaaattaa aaaaaatact tctccccctt
      661 cccccactag ccctccaaaa tgagttcgca gactttgtag ccctggtcga caaatcacaa
      721 tttgcttgtg agatagctat aaaagtgtgg agaaatagct tgaaatttag tataatatag
      781 ctaaactatt tgtttaaagt gagaaaaaaa tgggaaattt tagctttctt ttaaaaaatg
      841 acgaatatga atctttttca aaaccttgaa ttgaagctga gaatatgatt gctacatcaa
      901 ctgtggctac tgcctttatg gcgcgtcgtg ctttagagca ggctgtccat tggatatata
      961 gtcacgattc atatttagaa gctccctatc gtgctactct atcttcttta gtatgggatg
     1021 atgattttag ggatatcgta gattctgaac tccacaagca gatagttctg ttgattcggt
     1081 ggggaaacca tgctgctcat ggtggtgaaa ttaaggaacg agaagcgatt ttagctttgc
     1141 atcatttgta tcagtttgtt aattttatcg attattgtta cagcaatgag tttgtggagc
     1201 gttattttga tgagaagtgc ttaccacttt cagcaaacat caaataccga gaaactccac
     1261 aatctatgat aaagttacaa gacagtttac cagaactgcc tgattttcat gaacagatgg
     1321 ctgctcagtc cgtagaagtt caagagactt atactgaaaa acgtgagact gcagcgcaac
     1381 ggcaagatgt gcctttccat attgatcaat tgtctgaggc agagacaaga aagctcttta
     1441 ttgatatcga tctccgttta gcaggatgga tatttgaaga aaactgtcgt gttgagatag
     1501 ccgttgatgg tctcaagcac ggttcaggaa ttggttactg tgactatgta ctttatggta
     1561 aaaatgggaa aattttagcg attgtagagg ctaaaaaagc ctctgtcaat ccagaagtag
     1621 gggaagtaca ggtcaaagaa tatgctgaag ctttggagaa acatatcggc tatcagccaa
     1681 tttgctttat tacaaatggg ttgaagcact atatacttga tggtccgaac cgccgccaga
     1741 ttgcaggctt ttactctcaa gaagaattgc aattagtgat ggatagacgt catcttcaaa
     1801 aaccgcttga ggatatttct agtaaaatta gggacgatat ttccgggcgt cactaccaaa
     1861 aacatgccat tgcaagcgtt tgtgaagctt tctctaatca tcgtagacag gcacttttgg
     1921 ttatggcaac tggggcgggg aaaactcgta cagcagtttc tctagttgat atcttatcac
     1981 gtcataactg ggtaaaaaac gttctcttct tagccgatag aacttccttg gttaagcaag
     2041 cctatgattc gtttagaaaa ttactcccag atctttccgt ttgtaacttc ttagaagata
     2101 aagaaggagc tcaatcaagt cgtatggtct tttcaactta tccgaccatg attggagcga
     2161 ttagtggtca agaagaagta aatcaacgcc cttttactgt tgggcatttt gaccttatca
     2221 taattgacga atctcaccgt tctatttatc agaaatacaa gtccattttt gattattttg
     2281 atgcaagaat tgtaggctta acagctactc cgcgtcaaga tttagataaa aacacctatg
     2341 gattctttaa tttggagaat ggggttccaa catatgcata tgatttgaaa gaggctgtta
     2401 aagacggata tttagtagcc tatcattcta tcgaaatcaa actgaaacta cctacggatg
     2461 gtctacatta tgatgatttg tccgaagaag aaaaggaaca ttttgatagc aaatttgaag
     2521 acgatagctg tgaaaaagat attgatggga gtgtatttaa ttcctttatt ttcaataaaa
     2581 gtacagtaga aattgtttta aatgaactca tgacaagagg aattcagaca gcctcgggtg
     2641 atgaaattgg taaaactatt atttttgcta aaaatcatga tcatgcggaa tatatcagag
     2701 gtatttttaa caaccgctat cctgaaaaag ggagcgacta tgctcaggtg attgattata
     2761 gtattaagca ttatcagacc ttgattgatg attttaaaat taaggagaag tatcctcaaa
     2821 ttgcgatttc tgtcgatatg ttagatacag gtattgatgt accagaggtt gttaatttag
     2881 tcttcttcaa gaaagtacgc tctaaaacta agttttggca gatgattggt cgaggaaccc
     2941 gtctatgtaa agatttattt ggacctgagc aggataagga aaacttcttg gtatttgatt
     3001 atggggataa ttttgattat tttcgtgcag atccaagaga tggagaaggg tcgtcacatt
     3061 gtttcgttga ctcagcgttt atttaatatc aaagtggact tgattcgaga acttcaggga
     3121 ctccaatacc aagaagatca gtttgcgaga gcataccgtc agcagcttgt ctcggaactt
     3181 caaggtcgta tagagagctt aaatgagttg gacttcaggg ttcgtatggt tttagataca
     3241 gtttatagct ataggaaatt ggaaagttgg cagaatctaa ctgctgttac aagtgaaacc
     3301 attcaaaaaa atctctctcc gcttttattt gatgaagata aagaagatga gatggcgagg
     3361 agatttgatt tgtggttgct tcatattcag ttggggcaac tgacagctaa atcttccact
     3421 gttcatattt cccaagtgat gaagacggct agagctcttt ctgctattgg caatatcccg
     3481 caggtttttg agcaggctga aattatcagg aaagtacagg agcctgaatt ttggaaagaa
     3541 gttaacttgt ctgatttgga aaaaattcgt cttgctattc gagatttatt acagtttttg
     3601 gataaaacag accgtaaacc ctactatgtt aactttgaag atcgtatact ctccactgtt
     3661 cacgagacca cagcattttt gcaggtcaac gatcttcggt cttacaatga aaaagttgag
     3721 cattatttga aaactcatct ggatgaggag tccatttcta agctatacca taataaaaag
     3781 ttgacatctg atgatatgct tgcacttgaa aaattgctct gggaaaaatt aggtagtaaa
     3841 gcagactacc aaagtcatta tgaaaataag gcaattccga gattggttcg tgagattatt
     3901 ggcttagata gagagtctgc caatcgtatt ttttctaaat ttttgtcgga tgagaatctt
     3961 aatgccaggc agatttcatt tgtaaaattg attgtagact acattgtaga aaatggtttt
     4021 ttagagacga aagtgttaac gcaagagccg tttaaatctt atggttctgt tcaactactc
     4081 ttccaacacc aactaccagt acttcgtaat attgttcaaa tcattgaact tatcaataat
     4141 cgagctggag aagcggctta aattctaaag tgattgccat gctgagactc atttaaaatt
     4201 aaaaagagta gaaatttatg ctatatatga gaagttttat taggaagaat gtcatcgttt
     4261 tcctagaata cagtatcagt tgttaagtgg ttgataaatt tcaaagtaga tacttgtacc
     4321 acgatgtttg ttgatcgagt tattaacaaa agagctactt tgattttaaa gaaatagaaa
     4381 acaaaaagct gagcaagaat tcaattgcag gagaaaatga aataatactc aatgaaaatc
     4441 aaagagcaaa ctaggaaact agctgcaggc tgctcaaaac actgttttga ggttgtagat
     4501 aagactgacg aagtcagctc aaaacatggt tttgaggttg tagatgaaac tgacgaagtc
     4561 agtaaccata cctacggcaa ggcgacgttg acgcggattg aagagatttt cgaagagtat
     4621 aaatcttcct aggatagagc aaaacgcata gtatcaaggg ttttctgatg ttaaagactt
     4681 tctaccaggt tttttaaaag cataattgtt agttgtagtc atttattatt cttcaaagaa
     4741 aaatggtggg gcgaattttt tcagttcttc aaagcacttt tgagcagtat ctgcatcttc
     4801 acagatgata agacagacat cattaccaca aagggtagcg atagcgtcag ggaagctcaa
     4861 agtatcaatg atagaaccaa aggattgagc cagtccagga agggttttta gtaggacttg
     4921 gtgttgaact gggcgcatcc agacaagggc gtcttccatg tagagttcga gacgtttttc
     4981 ccattttgag atggaaccat tgttaagaac ataataagcg ctatcttctt cgcggacttt
     5041 tgataggttc atatttttga tgtcgcgtga gagggttgcc tgggttactt gaatgtcgtt
     5101 ctcagcaaga agggcttgca actcagcctg tgtatgaatc ttgttttttg tgataagagc
     5161 gcgtataagt tggtggcggt gttctgattt attcataata atgtaactcc ttttagcaag
     5221 gtaaggtaag catggactga gcgaggtcga cagtcaagtg gtagtctgta ttgtcacgga
     5281 tggtgatttc aaagtcagta gtatagagga ctaaacggag agtgtctcct tcttttagct
     5341 tgtaaatagt tggctgcagt tcaaattgaa cgtccatcca ttcatctgca gtaatatcct
     5401 ctactaacag taaatcattt ctattttgta aattaaggta accttttgtc acgactcgtt
     5461 gtgcctctgg tctaaatggc aattcacaga gattttccaa catgtgatag cgaccgttat
     5521 caatggttct agcacttaaa atagctggat aaggttgtag gtatttcttt tgcccaaatt
     5581 ctagcagttg ggcagataag agccccttgt ttgtactgga tttgatacga agattgagct
     5641 gagcgcgacc gtttaggtgg agatctttag tcacaggaag gttaatagta atctgattgg
     5701 ctttcccttg atagagctct gtattgaagg tttggtatgt cttaccatag cgctcaaaat
     5761 ccttatctgg gtactggttt tgaatagctt gctcttcttg accaagtgag aaggtttcac
     5821 agttttcttg cccaccgaag ttatcaagtg ataaccaagt ctgtggagct gtattgtcct
     5881 gccagataac agtaggaagt tgaaagtctg tttcctgtcc tagtaatttc ttggtcaata
     5941 aggcatttat ggactcacgg aagtcaattg attgccaatt gttcatgtaa acatgagcac
     6001 cattatggaa aaagagatgc ttgtgtatat gagtaggaag agcatggaac atctggtaaa
     6061 catgaagtgg tttgacattc caatcctgag aaccatgagt aaagacaacc tctgccttta
     6121 ctttatgggc attgagcaga taattgcggt catgccaaaa ctgattgtag tccccagttt
     6181 ttcggtctag ctgagctttc actttttcta agtcagcttg gtgagcttca ttgccacgga
     6241 tatagtcgcc agctaagaga ttacgagaat aggttaactc agcaagggag tcaaagtcct
     6301 cacctggata accacctggg ctagtcacca gaccgttttc acggtagtag ttgtaccatg
     6361 atgaaattcc tgcctcggca atgataactt ctaaaccatc gactcctgta gtcgcaagac
     6421 cattggacat ggtacctaga taggaaagtc ctgttgtagc aacttttccg tttgaccaat
     6481 cagccttgac ttgacgctgg cgcgtgtgat cagtaaaggc acggcaacgg ccgttaagcc
     6541 aatcgatgac atttttataa gcctcgattt gctggtagtc tccattagtc atgaaacctg
     6601 tcgagtcttt ggtaccaaca cctgagacat agagattggc aaagcctctc ggaaggaagt
     6661 agtcgtttag tgtatagcta gagttgatgt gagttagctt ttcctcagcc tctgctataa
     6721 gctcagcttt accttggggt tggacgagat ttagttgagg tttctctagc tcaatcttgt
     6781 gaggaagctt aacctcaagc tcgccctcca tcttgtagag agccttgtca ctagccttgt
     6841 cattggttcc ctgatgataa gggctggctg tcatgatggc agggattttt ccatcaaaac
     6901 gagggcgaat aatgctaacc tttactaggt ctgatagccc tttttggtca gtatcgacac
     6961 gagactcaac gtaaacgact tcacgaatga catcctggtt agaaaaagta gccaaactct
     7021 tgccgttaaa gtagtggtag tcattatcct ccggaataag accatcacta acaagttggt
     7081 cgataagagt atttcctttt ttggtgcgag tattgagtaa ctgatagaga ttttcaatca
     7141 agtcaccata tataatggga aatccagttt ctttacgaaa aacgtcacta tcttcgaagt
     7201 caaccaaata agaaaagcct aaaagttgaa aagcaacagt ataaaaaata tctgctgtca
     7261 gttcatcttc tgattgaaaa aatgtcagca ggtctgtttt tttatcagct gctaggatag
     7321 aaagtgggta gttggtgtct tgataagtga aaaagaaacg acgtaaaaag gtttcaagtg
     7381 agtctttgtg attggctgta ttttgtaaat caaagccaca tttttttagt tcagataaga
     7441 cattttcttt tggaaaattg atataactat attgattaaa acgcatagaa cctccatata
     7501 gaatgacagt taaggttatt atatcaaaaa aaaagcagaa agggaattgt taacttcaaa
     7561 aggaaataat ccaataaaaa tgaataaagt actaaattca atatagagaa cagagtaaca
     7621 ataagaataa atagatagg
//
LOCUS       DAVKBC010000065         6607 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVKBC010000065 DAVKBC010000000
VERSION     DAVKBC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.065"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            48..911
                     /locus_tag="VWX64_001880"
     CDS             48..911
                     /locus_tag="VWX64_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9191293.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFAYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            1294..1914
                     /locus_tag="VWX64_001881"
     CDS             1294..1914
                     /locus_tag="VWX64_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191294.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2000..2443
                     /gene="tsaE"
                     /locus_tag="VWX64_001882"
     CDS             2000..2443
                     /gene="tsaE"
                     /locus_tag="VWX64_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU9191295.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2433..2951
                     /locus_tag="VWX64_001883"
     CDS             2433..2951
                     /locus_tag="VWX64_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9191296.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            2959..3975
                     /locus_tag="VWX64_001884"
     CDS             2959..3975
                     /locus_tag="VWX64_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU9191297.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4059..5315
                     /locus_tag="VWX64_001885"
     CDS             4059..5315
                     /locus_tag="VWX64_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU9191298.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKVSSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5370..6536
                     /gene="recA"
                     /locus_tag="VWX64_001886"
     CDS             5370..6536
                     /gene="recA"
                     /locus_tag="VWX64_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU9191299.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
BASE COUNT         2098 a         1080 c         1492 g         1937 t
ORIGIN      
        1 aaaattttat aatgcaatta agcaaatagg aaggtttatt atctttaatg aatacactcg
       61 cagagaaatt cagattgaaa agaaaagagt tgagactctc ccaacaaact cttgcagaag
      121 gaatttgtga acaaagccag attagtaaaa ttgagagagg gcatttcatt ccctccgcag
      181 accttttgtt caaactctct caacgacttg aagtaccatt agattatttt tttaatgaac
      241 aaattgaaat taaatctaac ctctctaatt tcaagcaatt gtctgctcga ctattagacg
      301 atagaaatta tgacgatttg gaatatattt atagaataga gattgaacga agtacttttc
      361 taacactaga agaccgaact taccttgaat ggattaaagc tattattgac ttctatcaat
      421 atgacagtaa gtgtgaggca atttcttcat tggaaaatat attattaaaa gtctcttcaa
      481 atactctgat ttatttaaag gcgttgaata ctctatctaa tttctattcc ttagtgggtc
      541 gtgaacaaga atatgaggca aactactctc atttaataga gttgtatcag acaaaaaatt
      601 tggaccatca agagttttta tttgcctaca tcagagttcg ttacaactac gctcactacc
      661 tagtatcaaa ggaaaaatat aatgaagcca tccaagaagc tcttgaaacg attgaactct
      721 gtaaacaaag acagacaagc taccaattgg ctcctctact tattcttgta ggaaatgctg
      781 gagccaaatt tctagacaga gaacaagtca aaaattatta tatagaagca agagagttat
      841 gtaagattta taacaatcct ttaatgttga tgaagataga aaattatttg aaggaactag
      901 atactgttta gttaatcttg acattatagt ttttctgaaa cgttaaataa cctgtaaggc
      961 tgatagttag attaatacta tcagccttat aattatgtga ctctgagtcc gtctcgctcc
     1021 gtgaggtgcg agacaaaaca accacccgtt tgacggattt tcatgatttc aaatttatat
     1081 tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca atctcaaaac agtgttttga
     1141 gcaacctgtg gctagctacc tagtttgctc tttgattttc attgagtatt agtctctagt
     1201 gtttgtttag cgtcttaaag agacatttga gaagattaga aacagttctc tcttttctcc
     1261 tagtataatg attggtagga agggagagag aagatgaaat caatgagaat cttatttttg
     1321 ttagctttaa ttcaaatcag tttgagtagc tgtttcctat ggaaggaatg catcttgtcc
     1381 tttaaacaaa gtacagcttt tttcatcgga agcatggttt tcgtttcagg aatctgtgct
     1441 ggagtaaatt atctttatac ccgtaagcaa gaagtccata gtgtcctagc cagtaagaag
     1501 tcggtgaagc ttttttacag tatgttactc ttaattaatt tgttaggagc tgttcttgtt
     1561 ttgtcagata acttgttcat caaaaatacg ctgcagcaag aattagttga ctttttattg
     1621 ccatccttct ttttcctatt tgggctagat ttgctgattt ttttaccctt gaaaaaatac
     1681 gtgcgcgatt ttcttgctat gctagacaga aaaaagacag tgttggtgac tattttagca
     1741 acacttcttt tcttaagaaa tccaatgacc attgtctcac ttctgattta tattggactg
     1801 ggcttgtttt ttgcagccta tcttgtccca aattcggtta agaaggaagt ttccttttat
     1861 ggtcatattt tccgagatct tgtattggtc attgttacgc tcattttctt ttagagaaag
     1921 cctgtttttt atggatgtta tgatgataag tttagtagga aaatagacac aaaagaaaag
     1981 tttttggtat aataagagta tgtacacaaa aaatgaagaa gagttgcaag ccttagggga
     2041 gcgtttgggc catctattag caaagaatga tgttttaatc ttaactggag aactgggtgc
     2101 aggtaaaacg acctttacta aaggacttgc aaaaggatta cagatttctc aaatgattaa
     2161 aagtcccacc tatactatcg tgagagagta tgaaggtcga cttccacttt atcacctaga
     2221 tgtttatcgt attgaaggag atgctgattc tatcgacttg gatgagttta tctttggtgg
     2281 cggcgtgact gttattgagt ggggaaatct cttaggagat gccttgccag atgcttattt
     2341 agaattggaa attctaaaag aagcagatgg acgccgttta aattttcagg caaagggttt
     2401 gcgtgctgag aaattgttag aggagcttca atatggagta tgaattgctc attagggaag
     2461 cagagcccaa agatgcagct gaattagtgg cctttttaaa tcgtgtgagt ttggagacag
     2521 actttaccag cctagacgga gatggtattc tcttgactag tgaggagatg gaaatattcc
     2581 tcaacaagca agctagttcg gacaatcaga taaccttact tgcattctta aatggcaaaa
     2641 ttgctggtat tgtaaatatt acagctgacc agcgtaagag agtccgtcat attggagatc
     2701 tcttcattgt gattggaaaa agatattgga ataatggctt gggaagtttg ttgctagaag
     2761 aagcgataga gtgggcacaa gcaagtggca ttctgcgtcg tctccaactg actgtccaaa
     2821 ctcgtaatca agcagcagtc catctttatc aaaagcatgg ctttgtcatt gaaggtagcc
     2881 aagagcgtgg ggcatatata gaagaaggga aatttatcga tgtttacttg atgggtaaac
     2941 tgataggtta gtagaaatat ggttaaaaaa attattggaa tggtgctagc tttactttct
     3001 gtaactgtag taggagtagg tgtttttgct tatactattt atcaacaagg gacagaaacc
     3061 ttagctaaaa cctataaaaa aatcggcgaa gaaaccaagg ttattgaagc gactgaacct
     3121 ctaaccattc tgttaatggg agtggacacc ggaaatgttg aacgaactga aacttgggtc
     3181 ggtagaagtg atagcatgat cttgatgaca gtgaatccta aaacgaaaaa aacaacaatg
     3241 atgagtttag agcgggatat tctgacgcgc attgaatcag ggaatggtca ggctcatgaa
     3301 gcgaaactga actcagcata tgcagatggt ggagcagagc ttgctataga aaccattcaa
     3361 aaaatgatga atatccatat tgatcgctat gtgatggtca atatgagagg gttgcaaaaa
     3421 ctagtggatg cagtaggagg tattacagtc aataatatcc taggtttccc aatttctatc
     3481 agtgaccaag aagaatttaa tactatttct atcggtgttg gggagcaaca tattggggga
     3541 gaagaagccc tagtctatgc acgaatgcgt taccaagatc ctgaggggga ttatggtcgt
     3601 caaaaacgtc aacgtgaagt tattcaaaaa gtcatggaaa aagctctcag tttaaatagc
     3661 attggtcatt atcaagagat tctaaaagct ttgagtgaca atatgcagac caatattgat
     3721 ttgtctgcaa aaagtatccc taacttgcta ggctataaag attcatttaa aaccattgaa
     3781 actcagcagt tgcagggtga aggagagata cttcaaggtg tttcttacca gattgtttcg
     3841 agagcacata tgttggaaat gcaaaatata ctccgacgtt ctttgggaca agaagaagtt
     3901 actcagcttg aaaccaatgc ggttttattt gaagatttat ttggcagagc acctgttggt
     3961 gatgaagata attaactttt gatacaaata aaaaatcaat cgtaggaaaa ttcctgcgat
     4021 tttttcaaaa aaatacgaat agataggtag gaggaaacat gaaagcagaa atcattgctg
     4081 ttggaacaga gattttgaca ggacagattg tcaacaccaa tgcccagttt ttgtcggaaa
     4141 aactagctga gattggggta gatgtatatt ttcagacggc tgtaggagac aatgaagttc
     4201 gtctcttgtc tttgcttgag attgccagtc aacgtagcag tctggtgatt ttgacaggcg
     4261 gtttggggcc aactgaggac gacctaacca aacaaaccct agctaaattt ttagggaaag
     4321 cattagtctt tgatcctcag gctcaggaga agttggatat cttttttgcc ctgcgaccag
     4381 actatgcccg aacaccgaat aacgaaagac aagctcaaat tgtagaagga gcgattccac
     4441 tgccaaacga aacaggactg gctgttggag gaaaattaga agtagacgga gtgacctatg
     4501 tcgtccttcc aggtccgcca agtgaattga aacccatggt cttaaaccaa cttctaccca
     4561 agttgatgac agggagcaag ctgtattccc gagttcttcg tttctttggg attggcgaga
     4621 gccagttggt tacgattttg gctgatttaa ttgataatca gatcgatcct accttggccc
     4681 cttatgccaa gacaggagaa gtcactctac gtctgtcaac aaaggttagc agtcaagaag
     4741 aggcgaatca agcgctggat atcttggaaa atcaaatctt ggactgccag actttcgaag
     4801 gaatttcttt acgagacttt tgctatggtt atggggaaga aactagttta gccagcattg
     4861 tggtagaaga actgaaaagg caagggaaaa ccatcgcggc tgcagagagt ttgacggcag
     4921 gtcttttcca agctaccgtg gcgaattttt ctggagtttc aagtatattt aagggtggtt
     4981 ttgtgaccta tagcttggag gaaaaatcaa ggatgttgga tattcctgcc aagaatttgg
     5041 aagaacatgg tgtggtgtct gaatttacag ctcagaagat ggctgagcag gcacgaagca
     5101 agacccagtc tgattttgga attagtttga ctggagtggc aggaccagat agcctagaag
     5161 gacacccagt tgggacagtc ttcataggct tggcgcaaga tcaaggaact gaggttatca
     5221 aggttaatat tggaggcaga agccgagcag atgtacgtca cattgcggtt atgcatgcct
     5281 ttaacctagt tcgcaaggct ttattaagtg actaactttt gatataatag tagataggtc
     5341 tgaggatcat tagaatgtag gagaatagaa tggcgaaaaa accaaaaaaa ttagaagaaa
     5401 tttcaaaaaa atttggggca gaacgtgaaa aggccttgaa tgacgctctt aaattgattg
     5461 agaaagactt tggtaaagga tcaatcatgc gtttgggtga acgtgcggag caaaaggtgc
     5521 aagtgatgag ctcaggttct ttagctcttg acattgccct tggctcaggt ggttatccta
     5581 agggacgtat catcgaaatc tatggcccag agtcatctgg taagacaacg gttgcccttc
     5641 atgcagttgc acaagcgcaa aaagaaggtg ggattgctgc ctttatcgat gcggaacatg
     5701 cccttgatcc agcttatgct gcggcccttg gtgtcaatat tgacgaattg ctcttgtctc
     5761 aaccagactc aggagagcaa ggtcttgaga ttgcgggaaa attgattgac tcaggtgcag
     5821 ttgatcttgt cgtagtcgac tcagttgctg cccttgttcc tcgtgcggaa attgatggag
     5881 atatcggaga tagccatgtt ggtttgcagg ctcgtatgat gagccaggcc atgcgtaaac
     5941 ttggcgcctc tatcaataaa accaaaacaa ttgccatttt tatcaaccaa ttgcgtgaaa
     6001 aagttggagt gatgtttgga aatccagaaa caacaccggg cggacgtgct ttgaaattct
     6061 atgcttcagt ccgcttggat gttcgtggta atacacaaat taagggaact ggtgaccaaa
     6121 aagaaaccaa tgtcggtaaa gaaactaaga ttaaggttgt aaaaaataag gtagctccac
     6181 cgtttaagga agccgtagtt gaaattatgt acggagaagg aatttctaag actggtgagc
     6241 ttttgaagat tgcaagcgat ttggatatta tcaaaaaagc aggggcttgg tattcttaca
     6301 aagatgaaaa aattgggcaa ggttctgaga atgctaagaa atacttggca gagcacccag
     6361 aaatctttga tgaaattgat aagcaagtcc gttctaaatt tggcttgatt gatggagaag
     6421 aagtttcaga acaagatact gaaaacaaaa aagatgagcc aaagaaagaa gaagcagtga
     6481 atgaagaagt tccgcttgac ttaggcgatg aacttgaaat cgaaattgaa gaataagctg
     6541 ttaaagcagt ggagaaatcc gctacttttt cgatttttga ttcaagtttt tagattatat
     6601 atagtag
//
LOCUS       DAVKBC010000066         6115 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVKBC010000066 DAVKBC010000000
VERSION     DAVKBC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6115
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.066"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            244..2577
                     /locus_tag="VWX64_001887"
     CDS             244..2577
                     /locus_tag="VWX64_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9191300.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVVRGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            2590..4053
                     /locus_tag="VWX64_001888"
     CDS             2590..4053
                     /locus_tag="VWX64_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9191301.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILDPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            4053..5618
                     /locus_tag="VWX64_001889"
     CDS             4053..5618
                     /locus_tag="VWX64_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9191302.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLAEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYGNKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIPWVSISDMP
                     ISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATHNEAIISIF
                     PYAKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNHEEMKRIISK
                     VDLLFQKVSQLFE"
     gene            complement(5566..6111)
                     /locus_tag="VWX64_001890"
     CDS             complement(5566..6111)
                     /locus_tag="VWX64_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9191303.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT         2171 a          917 c         1187 g         1840 t
ORIGIN      
        1 tttgaaaaat agctcaccag cccgactgaa agtgcttata gaatgataat aagtcgcctg
       61 ccgaaaacag cggaaaatag cggtgttatg cggagataat ctgacgcgat gcgaaagtat
      121 attgcatact tattttcaac aatttagcag agtattttta taagtgtgat ataatagaag
      181 tataatttgt tctgatagtt tattttatgg agaagtagat ttttagaatg cggagggttc
      241 aatatggttg agtttataaa gtctaagaaa gaaatgagtg aggaggatat taaagcaaat
      301 ttcatcactc ctgctattgt atccaaagga tggaaaaatg gtgagcatat cgcttacgaa
      361 gaatacttca ctgatggtcg aattgaggtt agaggagata aggctcgtcg taaagaagga
      421 aaaaaatcag actattcact gtattaccaa tttggaactc gaattgcaat tgttgaggca
      481 aaggataata aacacagcgt tcgagcagga ttacaacaag ctattgaata tggagagatt
      541 ttagatgttc catttgttta ttcttcaaat ggtgatggct ttattgaaca cgaccgtatc
      601 acgagagaag aacgtgagct ggagttagac gaattcccta ctcgtgaaga attattttct
      661 cgtatgacga aggaaaaagg attgacgtac gaaattacag aagctatctc aactccatac
      721 tatacagacg ccttctcaat gaaaacgcca cgctattatc agcaaatagc tatcaaccgt
      781 actattgaaa cagttgtcag aggacaaaaa cgagtaatgt ttgtgatggc aacaggaacg
      841 gggaaaacgt tcatggcttt tcaaattatt catcgccttc gaaaagctgg tttggctaaa
      901 cgagttttat tcttagcgga tagaaacatc ttagtagacc aaacgatggc tgaagacttt
      961 aagccattcg aaaaggtaat gacgaaaatt acaccaaaac ttttgactgc tcctgaaaaa
     1021 ttaaattctt ttgaaattta tctagggctt tatcagcaac taactggtga agatggaact
     1081 gaaacacatt atcaaaaatt tgacaaagac ttctttgatt taatcgtaat tgatgaagcg
     1141 caccgtggtt cagctaagga aaacagtaac tggcgtaaga taattgatta tttcagttct
     1201 gcgacacaga ttgggatgac cgctactcct aaagaaacca agaatgcttc caatacggaa
     1261 tactttggtg agccaatcta tacttatagt ttaaaacagg gaatcgagga tggttttttg
     1321 gctccatatc gtgttatgag ggttaattta gatgtggatg tggatggtta tcgtccagaa
     1381 actggaaaag ttgatactaa cggacaatta atagaagata ggtactacgg caggaaagat
     1441 tttgataaaa ccattgtcat tgatgataga acgcaaagag ttgccaagtt tgtttctgat
     1501 tatatgaagc aaagcaatgc acgatttgat aaaacaattg ttttttgtgt tgatattgac
     1561 catgccgagc gaatgcgtgc tgcacttgta aaagagaatc tagacttagt ccaagaagac
     1621 tatcgttatg tcatgcaagt aactggtgac aacgctgaag gaaaagctca actggataac
     1681 tttatggatg tcaattctaa ttttcccgct attgtaacaa cgtctaaatt attaacgaca
     1741 ggagttaatg ctaaaacatg tcgtttgatt gttttagact ctaatatcca atccatgact
     1801 gaatttaaac aaattattgg tcgtggcaca cgtctttatc ctcaaaaggg gaaagaattt
     1861 tttacgatta ttgattttcg aaatgttacc aatttgtttg ctgaccctga ttttgatggt
     1921 gatcctgtga aggtgctgga aacaggtgcg aaaacagtca gtggttctac gcccggtttc
     1981 gtagatgagg aaggtgaccc agtagaaaaa tatatcgtta cagacaagca ggttaccatt
     2041 cttaattcta ctgttcaagt attagatgaa aacgggaaac tgattaccga aagcctgacc
     2101 gactacactc ggaagaatat cttaggtagc tacgccactt tgaacgattt tatcacagtt
     2161 tggcatacgg cggataaaaa gaagcttatc ttagacgaac tttataaaaa aggagtttat
     2221 ctagatgcta ttcgagagtc ggagggaata tcagaacaag aaatcgatga ttttgattta
     2281 ctcctaaaac ttgcctatgg tcaaaaagaa ttaaccaaaa cggaacgtat caataaactc
     2341 aaacaaagcg gatatttata taaatatagt gaggaagcgc gtgctgtttt ggaaatttta
     2401 ctgaacaaat acatggataa aggtattgga gaactcgaaa gcattgaaac attaaaactt
     2461 ccagaatttc agatatatgg tggaaccttc aaaatcatca atacttattt tggagataaa
     2521 aaacgatatt tacaagcaat taaagaattg gagcaagagc tatttacagt agcttaatga
     2581 aaggaaagta tgtcaattac atcatttgta aaaagaattc aagatatcac tcgaaacgat
     2641 gctggtgtta atggtgatgc tcaacgtatt gagcaaatgt cttggttatt attcttaaaa
     2701 atttatgata gccgtgaaat ggtttgggaa ttagaagaag acgagtatga gtcaattatc
     2761 ccagaggaat taaaatggcg aaattgggct catgctcaaa atggggaacg ggtattgaca
     2821 ggcgatgaat tacttgattt tgtcaataac aagttattca aagagttgaa agagcttgaa
     2881 ataacttcaa atatgcctat tcgaaaaacg attgttaaat cagcttttga agatgcgaac
     2941 aactatatga aaaatggcgt cttgttacgc caagtcatca atgttattga tgaagttgat
     3001 ttcaatagcc ctgaagatcg tcattcgttt aatgatattt acgaaaaaat tcttaaagat
     3061 attcaaaatg ctgggaactc aggagaattt tatacgccac gtgcagcgac tgattttatt
     3121 gccgaagttc ttaacccaaa acttggagaa tcaatggcag accttgcttg cggaacagga
     3181 ggcttcttga cttcgactct gaaccgttta agtagtcaac gtaaaactag tgaagatacc
     3241 aaaaaatata atacagctgt ttttggtatt gaaaagaaag catttcctca tcttttagca
     3301 gttacaaatc tgtttcttca cgaaattgat gaccctaaaa ttgttcatgg aaatactttg
     3361 gagaaaaatg ttcgtgaata tacggatgat gaaaaatttg acattattat gatgaatcca
     3421 ccttttggag ggtcagaatt agaaacaata aaaaataact ttccagcaga attacggagt
     3481 tctgaaacag ctgatttatt tatggctgtc attatgtatc gtttgaaaga aaatggtcgt
     3541 gttggagtta ttttacctga tggttttcta tttggtgaag gtgtaaaaac tcgcttgaaa
     3601 caaaaactgg tagatgagtt caacttgcat acgattatta ggttgcctca tagtgtcttt
     3661 gcaccgtata caggaatcca tacgaacatt cttttctttg ataaaacaaa gaaaacagaa
     3721 gaaacttggt tttatcgttt agatatgcca gatggttata aaaatttctc gaaaactaag
     3781 ccgatgaagt cagaacactt caatcctgtt cgtgactggt gggaaaatcg tgaagagatt
     3841 ctggaaggta agttctacaa atctaaatca tttacaccta gtgaattggc tgagttgaat
     3901 tataatttag accagtgtgg ctttccaaaa gaggaagagg aaatcttaga tccctttgag
     3961 ttgattcaga attatcaagc ggaaagagca actttaaatc ataagattga taatgtatta
     4021 gctgatattt tgcagttgtt ggaggacaaa taatgacacc agaacaactt aaagcaagta
     4081 ttctccaaag agcgatggaa gggaaattag tgccgcaaaa tcccaatgac gaacctgcaa
     4141 gtgaattatt aaagagaatt aaagctgaaa aagaaaaact tatcagtgaa ggaaaaatca
     4201 aacgagataa aaaggaaact gagatatttc gtggtgatga tgggaaacat tatgggaagt
     4261 ttgctgatgg aagcactcaa gaaattgatg ttccttatga tattcctgat acttgggagt
     4321 gggtgaggtt ttctacattg gttgaaattg tcagaggtgg ctctccacga ccaatcaaag
     4381 attatcttac ttctgaagta gatggaataa attggataaa aataggtgat actgaaaagg
     4441 gtgaaaagta tataaataat gttaaagaaa aaatcaaaaa atcagggctt aacaaaacta
     4501 gatttgtaaa aaaaggtaca tttttgttaa ctaattctat gagttttggt agaccttata
     4561 ttttgaatgt tgatggtgca atacacgatg gatggttggc tatttcgaac tatgaaaact
     4621 cattaaataa agattaccta ttctatattc tttcatcaaa tgtagtttat tctcaatttc
     4681 tatctctaat tagtggagct gttgtgaaaa acttgaatag tgataaagtt gcttctattc
     4741 ttatccctct ccctccgcta gctgaacaac aacgcataat agaagcaatc gaatcagctt
     4801 tagaaaaagt agatgaatat gctgaaagtt ataatagact agaacagcta gataaagaat
     4861 ttccagataa actaaaaaaa tctattcttc aatatgctat gcaaggaaaa ttagttgaac
     4921 aagacccaaa tgatgaatca gtcgaagttt tacttgaaaa aatacgagca gaaaaacaaa
     4981 aactctttga agaaggcaag attaaaaaga aagatttgga catttctatt gtttcccaag
     5041 gagatgataa ctcttattat gggaataaag acgaaacaac ctcttatcct atatatgaaa
     5101 tcccagaagc atggagatat attaaatttg ctagcctagt taacttcaga ataggaaaaa
     5161 ctcctccacg cagtgaagct actttttggg gaactgaaat accttgggta tctatatcag
     5221 atatgcctat atctggttat gtaactaata cgagagaatc tatttctaaa ttagcattaa
     5281 aatcaaagaa aatagacatt tcacctaaag gaactttatt aatgagtttt aaattatcta
     5341 ttggaaaagt tgccatattg gatattcctg ccactcataa tgaagccatt atatcgatat
     5401 tcccctatgc taaagaaaat attatcagag attacttaat gatatttttg ccacttatct
     5461 ctactttagg tgattcaaaa gatgctatca aagggaaaac attaaatagt accagtatct
     5521 ccgaattatt aatccctatt tctaatcatg aagagatgaa aagaatcatt tccaaagttg
     5581 atttactttt tcaaaaagtt tctcaacttt ttgagtaata agttcctgtt cctcaaaagg
     5641 agctaacgga attaatagct cgctcagtgt agttttagga atattatata aagcttgacc
     5701 tgatagttta gttattgctt tcaattgttt ataaaataac ggagaagaca agttaaataa
     5761 tagaaatttt gaaataatct ctgaactttc gaatggtgtt aattggaaaa taaatccacc
     5821 agccacaaca ccatcatagt ctttatcgat tcttgcaaac tttccaatat gttctaaaga
     5881 ggttgataca ggtgttatta gctgattatg ttttaaataa acttgctcag aggagatgaa
     5941 ttgtgtatca atgtagtaat cattatccaa cagagaaaat tctaaaggct taatattacc
     6001 accacgtata attctaacac ctttattatt aatgcttaaa tcgcccttct tgtaagaaag
     6061 acctgtattt attgaaaaaa tatcttttat ttttataaca acccaattca taggt
//
LOCUS       DAVKBC010000067         6058 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVKBC010000067 DAVKBC010000000
VERSION     DAVKBC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.067"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(297..1523)
                     /locus_tag="VWX64_001891"
     CDS             complement(297..1523)
                     /locus_tag="VWX64_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9191304.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1595..2260)
                     /locus_tag="VWX64_001892"
     CDS             complement(1595..2260)
                     /locus_tag="VWX64_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9191305.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2328..2525)
                     /locus_tag="VWX64_001893"
     CDS             complement(2328..2525)
                     /locus_tag="VWX64_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEU9191306.1"
                     /translation="MLNLQFAETMELTEAELETVYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            complement(2811..3674)
                     /locus_tag="VWX64_001894"
     CDS             complement(2811..3674)
                     /locus_tag="VWX64_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU9191307.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFLYIPIFE
                     AELESMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFTQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            complement(4070..5242)
                     /locus_tag="VWX64_001895"
     CDS             complement(4070..5242)
                     /locus_tag="VWX64_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU9191308.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     FFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILNIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            complement(5255..6003)
                     /locus_tag="VWX64_001896"
                     /pseudo
     CDS             complement(5255..6003)
                     /locus_tag="VWX64_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
BASE COUNT         2102 a         1130 c          956 g         1870 t
ORIGIN      
        1 aacatatata cggcaaagtg aagctgacgt ggtttgaaga gagtttcgaa gagtataagt
       61 aggctgaaaa gaatccagcc acagcatgga ctattatata gcagattgaa ataagatgag
      121 aacaaatcga ttgggaaagt aaaattaatt tctataaatg ttttagcaat tgtttcgtac
      181 tattttagat tcagtctatt ataacacatt cagaaaagag aaaaaagtct gttgattttg
      241 accatcataa aaagactggc aatccagtct caaacatata ttatagaaat tctccactaa
      301 atactttcac gaatattcag aagcataaca aaggcaacta gaagaaatag caataaaaca
      361 aagctaactg ccagagttcc aaagctagta gcaatggtta ccaaagctat tgtaaataag
      421 ctaggtaaaa caaccgtaat ggcaccgata gaggattgaa ctgctcccat tgactcctca
      481 ggtatttgtt taaagacgag ttcttgcaat ctaggagaga gaacacctgc gaaaaaggca
      541 tccaaggtac taaagatgag aatccagtca aaacgaactg tggcaaatcc tactagaaga
      601 agcaactgga tgacaagtga ggcatagaga gctgttttta tggaaatggt atgttgcaga
      661 tagccactta caaggcttcc gacaatcagg gctgacagtt caaaagtgga tagcaaggca
      721 agagattgac ctgtttgtaa attcaaaaag ggttgattcc tcaaaaatag agtagagaca
      781 ggaactgtaa catttatcac tgcttgacta gtagagataa taaacaaaac caagagcacc
      841 ttattcatat tccatatcaa tttcgatgat tggagcaaat gctggcaaaa ggattttaca
      901 gagagtcctt cttgatagtt aatcgttttt tctactttca agaggtcagt ttttatgaag
      961 aggataccta aaaatgcgat taaaaaggta agagcgttca gcaaggaaat gaactggatg
     1021 gagagaatcc ctagcaagac tcctcctaga atattactga ttgttttcac taaactaaca
     1081 gttgactgtt taaatccaat agcttctgcc agatggtctt gcccaataat tctaatgaaa
     1141 atcggagtga gcatggctcc tgaaaagtaa ctcaatgtgt cagacaagag gttaagcaga
     1201 caaataaatg ctactagcaa caaggagaaa gactgccctg aaagtgataa agaaacgata
     1261 gagtaaagca aaaattttgc aaaactaatg actgtgtatt tcaagacacg atgatgttga
     1321 aaatctgcca aaactcccag aaagatttgt aaaatttggg gaagggtttc tgaaatcgta
     1381 atgagtaaaa tcgccaaagg tgcaaaagac gcatctgcca cataattcag aaaggccaga
     1441 taaaaaatcg tatccccaag cgttgaaatc cactggttga tagttaattg cctaaaatct
     1501 ctattttgaa gaaatacttt catcacaact ccttcttaag ttcaaatggg aatctttccc
     1561 caaggataga ccgcgatact actaacaacc aaaattacag taacatcaaa agctgaccaa
     1621 tgccattgta gactatatgc agtccaatag gccaataaat tgactttgtc attctaaata
     1681 agactgcaaa tataagacct ccacccatat agaagacaaa gtctgtcaag acccaaccgt
     1741 gattactaat gtgcgagacc ccaaataaaa cagcggaacc aagtacatct agcccccatt
     1801 tctttccttt ttccagagca gtcatcacta atccacgata aatcatgtct tcaaaaatgg
     1861 gacctgcaat cacaggataa aaaaaataca tcaaaaatgc cgtagctcct gtaaaagtag
     1921 gagcagcatg ttgataagaa atttcatttc gagtaggtgg gaaaagaaaa aaggtgacaa
     1981 aattccaagc aacaaaagca agcagagcta ggaaggaata gaaaagatag gatcctttaa
     2041 actttctact attgattttc tgccatttcc ccgaccaaat catagcaata agagcaaata
     2101 aaaccacaag aaaattcaac atcatatccg acagataata ggcaaagtca gatagcccag
     2161 caacaaggtc gctgcgtaaa actaaaacac tgaacttctg gtcagcaata actagtagaa
     2221 aaactataat aaagtagcgg tgtgagatta tctttttcat tctattttct cctatactat
     2281 gaaataaaga cagtccctac ccaagaaaaa ggcaaggact ctgaatatca ataatggcga
     2341 cgattaacag tggaagaatc atggttaaaa tatttcttcc agaaattagt gattgaccaa
     2401 gacgttccta aacctcccca agcaccggct gggataacag cattattccc aaattcccct
     2461 ccataaactg tctccaactc agcttctgtc aattccattg tttctgcaaa ttgtaaattt
     2521 aacatctttt acactccttc aattatcttc atttgtaaac cacttctgcg acctaggatt
     2581 tgcttcaagt gctttacaag tacagtataa cacgaaaatt ggcttatttt aaaaaatcgc
     2641 atatttgata ttttttctta tagaaatttc ttatttgcga ttttgataga tttgattatt
     2701 tccctggtat aataaagtta ttactaacaa ggagggaagt aatatgaaga aacaagtttt
     2761 aacattattg acgatcgttg ctgagattat tattattttg ccatttctaa ctaatcgata
     2821 agctttttgt attgctgcaa acgcaattca aaaagggcta ttaattgtgg attttctaat
     2881 acttgcagag attgggtaaa gcgttcaatc tctttttgat tgcttccctt tgtttgaaga
     2941 aagacactca tcttctttaa aaattgccac gatacttttt caaaaacatc gtacggacgc
     3001 aacatgctct ccaactcggc ttcgaagatt gggatgtata agaaaagttt tcgctccatg
     3061 agttctgata agatatttaa gagtccttgc ttcatataca atcgattgtg tactaactct
     3121 ttaaattctt tggatttttc gagtaaggag gttgataaaa agatcagatc ttgattgctc
     3181 aagaagggca gagtattgca aaagagatag agttcaaacc aggtccaaga ctcgatagca
     3241 tagagatagg tggtcaaaaa ctcgctatcc tcctctgcta gtgggtagct tttatctagt
     3301 gagtggatgg catctttgat tacaatagca ttcaaacgac gataagtctc tgccatctgt
     3361 tcttgctcga cttcctccaa cagttgctct aagccagcta tatcttgatg agcaaagcga
     3421 tccacaacct ttctaccaat ctgcatatgt ggagattctt gatagttgtt gagcttgtgc
     3481 ccaaactcat caaaggtcac attgatccct tggatggcta atatgagctt atcagcagac
     3541 aacatggact gccctagctc aaacttggac aactgagaag ctgttagccc gtcacaagcc
     3601 acatctgact gcttgagctt tctcgccaaa cgtaattcct tgtaaaattc ccccaattcc
     3661 attttttcaa tcatcctacc acctcctagc ttttgcatat tatatcatta tttgtgttca
     3721 tttgtcaaaa tattctgata gttagaaaaa ataaaaaagc cagccttaag ctgactctaa
     3781 aaggaccgag ccttgtacaa tacagaactc aatcctcgtt ctaaatagaa tgtctaactt
     3841 ttttgggcag tacacgagct tggggaacag ccactggaac gatgaggtgt gagctcaaaa
     3901 tatcctccag ttatgttttt cctaatagta taccggaaga gtgaaaggat tttataatgg
     3961 agcggttaca aagaacctac tttctattaa acagtatact atgaaaatgt gaaaatttaa
     4021 catttttttg tacaaatttt ataaattatt gcctttttaa tatcaatagt taatctctta
     4081 tccagatccc ccttgtgtaa actttatctt tataagcttc aaggccccta tcccatctat
     4141 ttgcaacaat tagatcactt tgttttgtaa atagttcaaa attcttttca aaaattacgt
     4201 tatctatact aacgtttaaa tttggttcat atactaaaat ttttataccg acaatcaata
     4261 gttcattaat tatatttaaa atagctgact ctttgtaatt atctgaatta tatttcatcc
     4321 ccaatttata tattcctact atctttggct ttcgttccaa tatttgttta actatgaact
     4381 gttttctatt tgtgtttgaa atatcaatcg cttctatcac tggagcattt atttctataa
     4441 attctttttt taattgttta gtatctttgg gaagacaata tcctccaaat ccaaaagaag
     4501 gattattata aaaatttcca attcttggat ctaaacaaac accttttatt acaacttcag
     4561 catttaaact tctcctctca gcaaaaaaat ctagttcatt aaaaaaagca acacggagag
     4621 ctaagaatgt gttagaaaaa agcttaattg cttctgcttc agtaggagaa actaacataa
     4681 catttttaat attggcagta ctatgagtac taatcgaaag gaacaactct gcaatttttc
     4741 ttccttcaac tgtctcatct ccaacaacta tgcgacttgg atataaatta tcatatatag
     4801 aacaaccttc tctcaaaaat tcagggacaa aaatgatatt ttttgtatca aacagccttt
     4861 ttaatttgtt tgaaaagccg atcggaactg ttgactttaa aataatcttt ccattaggtt
     4921 ttaccctcag aatcttcgat accgtttgtt cgatttcata tgtattaaaa ctaccaattt
     4981 tctcatcata atctgtcgga agcgcaataa tataataatc aatattattt ttaatttcag
     5041 aaaatgtatc aaaaaaagta atatttaagt tattctcgca aaaaaacttc ataagctctt
     5101 catttttaga tggaagaatg ccctttttta aattatttat ttttacagaa tctatatcat
     5161 atgcaacaac tttatattta gatgcaaata gtaacgcgta ggccagccca acatgcccca
     5221 aaccaattac tgctatattc ataaaactac ttccttattt cttaatccaa aatctaatag
     5281 aataagctgc cccattcctt aaatacaact ctttaatatt gtttaaaagt ttttcaactg
     5341 atttccagat tatcaaaatc tgagatttat agcacaatat tgatgatatt ctatcaatat
     5401 aatgtttttc atcaagttcc tcttgataca tttttaattc tttagttttt cccatataac
     5461 taaccatact actatcactt acatatggga agtcctcata atatattact ttataacgca
     5521 taaattcaag cgcccttcca atactattca caaaaacatg agcaacatgg tcaccaagtg
     5581 aaagcggaca atatacgaca catttgtcgt ctaaatgcat taacagctct tttatgatat
     5641 cattctttaa tgtgtcctca ttttttaatt cactatagat atgacggtat agaaaattgc
     5701 catttctatc tttcctatag agacattcat agtacgataa gtgtctaaaa tcacattgta
     5761 gacgttcaca agctaacctg tcttctttct tcctttcttc aatcggatat ttcccaaggt
     5821 tacacaactt atgaaattgc ttagcagagg gctgtagctg ttggctcaaa gggtaaccag
     5881 aaaatatagt aataacaagt acaatttctc cttctgaagt taattttgaa atataatcac
     5941 cacaggaaaa aattgcgtca tctaatgtgg agataaaaag atatacttag tattgttact
     6001 cataaccatt ccctctacaa tttatctaaa aactcactaa gtgtctgatt aaattcca
//
LOCUS       DAVKBC010000068         5949 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVKBC010000068 DAVKBC010000000
VERSION     DAVKBC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.068"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(277..828)
                     /locus_tag="VWX64_001897"
     CDS             complement(277..828)
                     /locus_tag="VWX64_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9191309.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(1178..2002)
                     /gene="nadE"
                     /locus_tag="VWX64_001898"
     CDS             complement(1178..2002)
                     /gene="nadE"
                     /locus_tag="VWX64_001898"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU9191310.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(1999..3459)
                     /locus_tag="VWX64_001899"
     CDS             complement(1999..3459)
                     /locus_tag="VWX64_001899"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU9191311.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIYNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRLVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFPEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(3575..4063)
                     /locus_tag="VWX64_001900"
     CDS             complement(3575..4063)
                     /locus_tag="VWX64_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191312.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(4053..4262)
                     /locus_tag="VWX64_001901"
     CDS             complement(4053..4262)
                     /locus_tag="VWX64_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9191313.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(4647..5099)
                     /locus_tag="VWX64_001902"
     CDS             complement(4647..5099)
                     /locus_tag="VWX64_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191314.1"
                     /translation="MIYVLSNFLYAISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIV
                     AIVVNTILLVLFYFLLSYIFYLYKLKSGLVFGILVALLLFIPNILNTMMMNTSNDLFI
                     KAIELLPFYSLPVFVASNTMSISQYLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(5163..5375)
                     /locus_tag="VWX64_001903"
     CDS             complement(5163..5375)
                     /locus_tag="VWX64_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191315.1"
                     /translation="MKLNKFNFLKENIRNLYSSGVIYLGLLISFIPPILVTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHAN"
     gene            complement(5391..5884)
                     /locus_tag="VWX64_001904"
                     /pseudo
     CDS             complement(5391..5884)
                     /locus_tag="VWX64_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452046.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT         1817 a         1288 c         1027 g         1817 t
ORIGIN      
        1 tcgatagagg attctatttt aaatttaaca acagctagga ttacactata aaaagtacat
       61 taccacctgt tcggctggag aatctagtcg attagctccc tcttagttac aagcttaaag
      121 cgatttttta actaatacta aaccagatta aagaaggaac tagaacatct gtcttgtact
      181 aatcaatatg ctattttaaa attgcaaata aacttggaat gctaattatt atatttacaa
      241 taaatagttg acttcgatag aaacagaaaa tagaattcaa cattcttccc tacttatacc
      301 ataataaata agatccgcaa gatagccttt tctctctaca ccattaacaa tggtttgtag
      361 ataggacatt ccagcctttt ccatgacacg acctgaagct gggttgagac tggcataacg
      421 tgctctgacc ttttgaaaac ctgcttgagt aaaacaaaag tccaagacag ctttcaaggc
      481 ctctgtcatc ataccatgtc cccagtaagc cttgcctagc acatagccga tttcacagct
      541 taaatcagcc tcgtctatct taacgatgct gatatctcct atcacttgct ctgggttttc
      601 ttttagacaa atggcccatt tgtaatagtt gagattagta taggaagcaa cccaattgcg
      661 aatcgagttt cgagtgattt cgacatcagg atggggatcc caggtaacat aggtcagatt
      721 ctcagcggat gaagcccaat tttgaaacat ggcttctgca tcactctcca caaatcttct
      781 taaaatcaaa cgttctgtct gtaatatttg cgtaccaata gatttcatga tgctacctca
      841 cttccttatt tctatgctcg tagtaaaaag gctcaactca gtaacagcta gaaaacgagt
      901 ttgtcttcta atttcttgac gcagtcgctg cctggtttga aatgcgatct agcaagcttt
      961 ttcaaaccta gtcatcgttg caggggtaag acgatgaaat cgaactcttc gagttaccga
     1021 atctgcctca ttttcttatt tctaaactcg aggttcaaga tcccccggac cttctctcac
     1081 tttcttattt caagatgaga ggctgaaaac ctccagtgga ggtttttctt gctttttaat
     1141 ttcagggcaa gaagctaaaa aggtcccccg gaccttttta ctcccaaaag tcatcaaata
     1201 cggtgatggg taagtggcgt ttgtgttggc ctttgtgcca ccagttttca atggtcgctt
     1261 gagcttctgg gctgattgtt ttgccttcta ggtagtcgtc aatctctgcg taggtgactc
     1321 caagtgcgac ttcgtcagct aggcctggtt tatcttcttc taggtctgcc gttgggattt
     1381 tttcataaag ggctggctct gcgccaagtt tctgcaagag ctgttttcct tggcgtttat
     1441 tgaggcggta aagagggaga atatccgcac cgccgtcacc aaacttggta aagaaacctg
     1501 tgatattttc tgcggcgtgg tctgttccaa tgaccgctcc gctatgggaa ccagcaaggg
     1561 catactgagc aatcatacgg caacgtgcct tgatattccc cttgttgaag tctgaaacag
     1621 gactacctgt cgcttcaact gcagctgtca tggcatcagc tgattccttg atattcacaa
     1681 ccaagctgac atctggctgg atgaaggcta gggctttttg agcatctgct tcatcagctt
     1741 gcactccgta tggcaggcgg acagcgataa atttgtagct atcgtctccc gtttcagctc
     1801 gcagttcttc catagctaat tgcgccaaac gtcctgccaa ggttgagtct tgtcccccag
     1861 aaatccctag tacaaaggtt tttaggaagg gatgtttttt cagatatctt tttaagaaat
     1921 caatagaacg acggatttct tcctgggcat caatcactgg tttgacaccc agctcttgga
     1981 taatcgtttc ttgcaaactc attcttcttc tccttcacca agggcttcct tgcgcatctt
     2041 atcaatcaag tccatcttat cttgccatac gtcacgcgcc aaatccactg gatagtgctg
     2101 cggattgagc acacgcttat actcatccca caacttgtca aattccttac gggcataatc
     2161 ctgaatgtca gtcaaactag gcaagttgta aactaatatt ccttctttga agatatccac
     2221 caagagagga acggcatcaa aattacgaac cgtcttcttg atgtatgtat aggtcggatg
     2281 gaacatcttg atttctgtca tgtcgctaat atccacacca tcataagtga tgtagtcacc
     2341 ttctgacttg cctttttcac gactggtaat gcgccacacc tgcttcttac ctggcgtcga
     2401 cactttttcc gcattattag acagcttaat cgtattgcgc atctggccgt tttcatcttc
     2461 gattgcaaca atcttgtaaa ccgccccaag agccggctgg tcataggctg taatcagctt
     2521 ggtacccaca ccccagacat caatcttggc cttttgcatc ttgaggttaa ggatggtatt
     2581 ttcatctaga tcattagaag cataaatctt agcctctgga aatccagcct cgtccagttg
     2641 ctgacggact ttcttagaaa tgtaggcaat atccccagag tcaatccgca cacccataaa
     2701 gttaatctga tcacccagct cacgcgccac ctgaatggca gctggtacac cgatgcgaag
     2761 ggtatcatag gtatccacaa gaaagacaca atttttgtgg gtcgcagcgt aagccttgaa
     2821 agcctcatag tcattgccat aaacctgtac caaggcatgg gcatgggttc ccaaaacagg
     2881 aatgtcaaag agcttacccg cacgcacgtt gctggttcca ttggcgccac caatcaccgc
     2941 tgcgcgtgtt ccccagatgg ccgcatccat ttcttgagcc cgacgtgtcc caaactccat
     3001 caagggttca tcttcgataa ccaaacgaat acgagctgcc ttcgtcgcca ccaaggtctg
     3061 gtagttgacg atgttcaaaa gagccgtttc gaccaactga cattgggcta gaggtccttc
     3121 cacctgcaca atcggttcat tagcaaaaac caaatcccct tcttgggcag aacgaacggt
     3181 caactccaac ttgaaattgc gaaggtaatc caagaacgcc ccatgataac caagcgactc
     3241 caaataggct atatcactat ctgaaaaacg caagtcttca agatagttca caattctttc
     3301 caaacctgca aaaaccgcat agccgttctt aaaaggctgt tggcggaaat acacctcaaa
     3361 gaccgccttc ttattgtaaa tcccttgatc aaagtaaacc tgcatcatgt tgatctggta
     3421 caagtccgtg tgcaatgtca aactatcatc tggatacata cttttcctac ttccttagct
     3481 agaaacccat gaaaattttc aagaactttc atgtattcca ataaattagt actattatat
     3541 cacattttag ctggattgag aaaagagtaa caagctattc tccactctcc aattcatcca
     3601 tatcttgttc aaattttttc tgagcccatt cgccatagct cttaagacca agattgccaa
     3661 taaagaccca cggaaggtaa atgacataag taatgaccca agcagacagg tatttaaaat
     3721 tcaaaggatt gtgctgataa atttctatgt tgaattgata attctgcaac atcaaaagag
     3781 ccgtaatagc caaggttagg aaaaaacaac ccaaaatcgt aaaatgaaaa cgactatagt
     3841 aggtcactcc cagataacgg gcacgattga aaaagtaaaa tgtccctatg atgataacga
     3901 ttagcagcat attagaatta aaaaggcttg gtgctaatac tgaaatgata taagatagga
     3961 gcgacaaagc aatgcagata tagaaacttt cagagcccgc tttattgaac agttgttctt
     4021 ctctttcgtc tagtaattga taataataaa atctattttt catcttcttc ctcccaaaat
     4081 agttggtcta gggttttccc taaacatctg caaatagact ggcagagcga gagactggga
     4141 ttgtattttc ccgcctctat caaaccaata gtctggcgtg tcaccccgac agcctctgcc
     4201 agttgacctt gtgttaaatc acgctctacc cgagctaatt ttaattttaa atttttagcc
     4261 accttcgtcc tccttatagt tttaatactc atctactctt aaaaaatcca aaaccaacac
     4321 aagctatcag ctatttatta taaccccatt aatttgcact ccagtattat cttcagccga
     4381 aaatcagtat tttaggttgt ttgaaataaa cttcctagtt tactctttta tttttattta
     4441 gtattagctt tagtaggatc ttttaaacga gtttttattg cttatatttc ttgtttagtt
     4501 tagttggttt catatcacta ttatataatg cttttggaaa tgagcctagt ataagtcaaa
     4561 aacgtgttga atagtgaaag caggagcata ccaagatgac tgatttttta ctgtatttta
     4621 ggtatgcaaa ataatactaa atgaaactaa aatgaatact tcttgctttt cttgagagtg
     4681 aaaaagtaca ataaaatgat tgtagtgatt agcacaagat actgactaat agacatcgta
     4741 tttgaagcca caaatacagg taaagaataa aaaggaagaa gttcaattgc tttgataaac
     4801 aaatcattac tagtattcat catcatcgta tttaatatat tagggataaa gagtagtaaa
     4861 gctactaaaa taccaaatac caagccactt ttcaatttgt ataaatagaa aatgtaagat
     4921 aatagaaaat aaaacaggac taacaaaatt gtattgacta caatagctac tataaaatct
     4981 aatcctaaat cacctggaat acccaattta cttactatga ctagtaacac aatgccattc
     5041 aaagcataaa taatggaaac tgagatggca tatagaaaat tagacaagac gtaaatcatc
     5101 cgattcttct gttgattata aaacaaactt accgtattgt gggaaaaatc tctactaatg
     5161 actcaattag catgtataac agccattaac ataccgagca tagcataaaa gtttgaaata
     5221 tgcttaatac caagcgatgt cccttgagtc tttagaataa agaatgtaac caatatcggc
     5281 ggtataaatg agataagcaa accgagatat attacacctg atgaatataa atttcttata
     5341 ttttccttaa gaaaattaaa tttatttaat ttcatgatta taaccttcct ttattttgaa
     5401 cgatttagat aaatatcttt aagcgtctct tttttagttt caaaatcaac tactttaata
     5461 gagttttcgt taaaaaattt aaaaagctca ctactttgaa tattcccaga catagtaatt
     5521 ctcagtccct cttcctgaac aatatcccca aattcttgtt tggtaatgaa aatgtctcta
     5581 tctgtagctg atgaaaaagc tatctcaaac aagaaattat gactatcttt tcctactttt
     5641 tgaaatgtca aaagcccgct ctccaagaaa agaaccctct cacaaatttc ttcaatacat
     5701 tatcactgct tataatatta cctgaagtcg gttgattatt ctgaacaaga attttcatca
     5761 acgtactctt accaactcca tttctcccta cttgaccaac aatttcaccc ttgttaagtg
     5821 caaaatttat atctttgaga atgattgaat gaccataatg cttacttaca tttataactt
     5881 acatttttta ttcctcaatt aatattcatg gtttgctctt tgattcttat tgagtttaaa
     5941 aagttgcgc
//
LOCUS       DAVKBC010000069         5689 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVKBC010000069 DAVKBC010000000
VERSION     DAVKBC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.069"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            109..273
                     /locus_tag="VWX64_001905"
     CDS             109..273
                     /locus_tag="VWX64_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9191316.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPAIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            357..923
                     /gene="amaP"
                     /locus_tag="VWX64_001906"
     CDS             357..923
                     /gene="amaP"
                     /locus_tag="VWX64_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU9191317.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            935..1105
                     /locus_tag="VWX64_001907"
     CDS             935..1105
                     /locus_tag="VWX64_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU9191318.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1144..1752
                     /locus_tag="VWX64_001908"
     CDS             1144..1752
                     /locus_tag="VWX64_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9191319.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1783..1986
                     /locus_tag="VWX64_001909"
     CDS             1783..1986
                     /locus_tag="VWX64_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9191320.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2096..2368)
                     /locus_tag="VWX64_001910"
                     /pseudo
     CDS             complement(2096..2368)
                     /locus_tag="VWX64_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2513..2959)
                     /locus_tag="VWX64_001911"
     CDS             complement(2513..2959)
                     /locus_tag="VWX64_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9191321.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            3029..3688
                     /locus_tag="VWX64_001912"
     CDS             3029..3688
                     /locus_tag="VWX64_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU9191322.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWKLLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILITSSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(3740..4891)
                     /locus_tag="VWX64_001913"
     CDS             complement(3740..4891)
                     /locus_tag="VWX64_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU9191323.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDNQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(4906..5637)
                     /locus_tag="VWX64_001914"
     CDS             complement(4906..5637)
                     /locus_tag="VWX64_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191324.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
BASE COUNT         1757 a         1035 c          958 g         1939 t
ORIGIN      
        1 gattttttga tattaaaata aaaaaggagg gtaggcagtg ttgtgatcaa ttattgctgg
       61 aggtcttatt ggtctcttgg caggtaaaat cactaaaaaa gtagttctat gggaatcatc
      121 gcaaatgtat tcgctggttt agtcggggca tatgcaggac aatctctttt aggtagttgg
      181 ggtccagcaa tcgctggaat ggctttgctc ccatctattg taggtgcagc gattgtgatt
      241 actgtagtgt cattctttac aggtagaaag taaacttttc gccagtaaag ttagcaaact
      301 atttttaaat caatgacggg aaaaatagtt taaatgttaa atcgaaagga ttgtatatgt
      361 caaaagcaaa gaaaatatgt ttcattattt tctgtatttt aatcttgaca attttccttc
      421 ctgttttgat agattatcat caagttagtg atctaggtat tcatctactt agctggagac
      481 agaactccgt agttgaattc tatcttgcta gatatgtctt ttgggggaca gtggttctat
      541 caactttagt tttattatcc attttagttg tgatgtttta tcctaaacgt tacttggaaa
      601 tccaacttga aactaaaaac gatacattaa aattaaagaa ttcggcaatc gaaggttttg
      661 ttagaagttt ggtgagtgat catagattga tcaagaaccc aactgttcat gtaaatttac
      721 gaaaaaataa atgtttcgtt catgtagaag gtaaaattct tccttcagac aacatcgctg
      781 acagatgcca aataattcaa aatgaaataa ctaatggatt gaagcagttt tttggtattg
      841 agcgtcaagt aaaacttgaa gttgcagtaa aaaattacca accaaaacct caaaacaaaa
      901 agactgttag tcgtgtgaag taaggaagta aaaaatggaa tggcttaaac aatatcgata
      961 tccaattatc gctggtctca taggcgtatt tctggcttgt ttgattgtct cctttggctt
     1021 cttcaaaaca atatttgtat tgattttagg agcactggga gttgcagctg gattatatat
     1081 cgaaaaaaac tatatagata aataaaaaaa taaaaattac taatttaatt aaaggagttt
     1141 catatgtcaa acgaaaaaaa cacaaacact aacgtagaaa agaaagatgc tactgttgta
     1201 gctcacgaaa tcaaagggga acttacttac gaagataaag ttatccaaaa aatcattggt
     1261 ctttcactag aaaacgtttc aggtcttttg ggaatcgatg gtggtttctt ctcaaatctt
     1321 aaagaaaaaa tcgttaacag cgatgacgta acaagtggtg ttaacgtaga agttggtaaa
     1381 acacaagttg cagttgactt aaacgttatt gttgagtacc aaaaaaatgt tccagcttta
     1441 tattcagaaa tcagagaaat cgtatcttca gaagttgcta aaatgactga cttggaaatt
     1501 gttgaaatca acgtaaacgt tgtcgacatc aaaactaaag aacagcatga agcagactca
     1561 gtaagccttc aagatcgcgt atctgacgtt gctgaatcaa caggagaatt cacttcagaa
     1621 caattcgaaa aagctaaatc tggtcttgga tctggtttct caactgttca agaaaaagtt
     1681 agcgaaggtg tagaagctgt taaaggtgca gcaaatggtg tagtatctca cgaaaacact
     1741 cgtgtaaact aagataaaat aaatataaca ggagaaatta tcatgtcagt agaagaaaaa
     1801 ttaaatcaag ctaaaggttc tattaaagaa ggtgttggga aagccatcgg tgatgaaaaa
     1861 atggaaaaag aaggagcggc tgaaaaagtt gtttctaaag taaaagaagt cgccgaagat
     1921 gccaaagacg ctgtagaagg tgctgtagaa ggtgttaaaa acatgttgag tggcgacgat
     1981 aaataaggtt aaaagttact ttatcttttt ggtaacatta gtcaaaagag tctgagtcaa
     2041 gatgattctc agaaaacaaa aagctagaga ttcccaattg cggaactcta gctttttaat
     2101 tttgcctctt tctcttatta tatttcagca ggttgttggc catgagtatg aatcccatgt
     2161 caattctcac ttgacgcttc cctctcagat gacatctctt ataacccaaa caaaccttta
     2221 tctgcccaaa gacagatttc atatcaatct tacgtttagc gaaaatttgt ctacccttgg
     2281 aagataaaag tgcctgatat tctttagttt ttaaacactg gtaacgttca ttcatataca
     2341 gtcccttttg aggggctgat tcaggttcat aatcgcagtc aacattgatt tcaaggctgt
     2401 ttgctttcta tctccccttt tttatgatgt atagtaaaat gaaataataa caggacgaat
     2461 cgatcgggac agtcaaatcg atttctaaca atgttttaga agtagaggtg tactattcta
     2521 gtttcaatct actatatttt cgtacaggtg cttcaaccat ttgaacgatt tcaaatcctt
     2581 ctttttggta aagattctga gctctttgat ttgcctcgaa gacatttaga gaaatactat
     2641 ctatatcttc attttcaaag gccaaactaa caaatttcct taaagcctgg ctacctaagc
     2701 cttgctcctg tttctggggg ttgataaaaa atctcccgat atgaagattg ctgtcttcta
     2761 gcctgatttt ctggattagt cccacaaact cttgttcatc aaagattgaa aagactcctt
     2821 ccaaggcttg aagggtcagt agaaaaggaa tccttggtcc catccattgt tcttgaaagg
     2881 atttgcctag ggagttggac cactggcata caaattgagc gttttctgtg ctcacctttt
     2941 cttcaaaacg aattgtcatc ttttcctcac catcttatct atgtttctcc attatactat
     3001 ttctcccatt ttttacgaat agataagtat gattgatttt tatttttttc tcgtcgggag
     3061 cattctcgct tcctttcttg gtttggtcat tgaccgtttt ccagagcaat ccattatcag
     3121 ttcagccagt cactgcgatt cctgtcagac tcgcttgcgt cccttagatt tgattccgat
     3181 tctctcacag gtcttcaatc gctttcgctg tcgctactgc aaagttcgct atcctgtctg
     3241 gtatgccctc tttgaattag tcttaggact cctctttctg ctttactctt ggaaattgct
     3301 ttccttgggg caagtcgtcc taatcaccgc tggtttgacc ttgggtatct acgactttca
     3361 ccatcaggaa tatcccttac tggtctggat gactttccac ctaatcctaa taacttcctc
     3421 tggctggaat ctggtcatgg tctccttcct catacttgga attttggctc attttatcga
     3481 tatccgcatg ggcgcagggg atttcctctt tttagcttct tgtgctctcg tctttagcgt
     3541 aacggagtta ctgatcttga ttcagtttgc ttctgcgacg ggtatcctgg cctttatcct
     3601 gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta cttgtttgat
     3661 tatttttggt aagctactgc ttgtctgata aaatccaatt tctgccatat atccttcatg
     3721 aaattatttc acagttaaat tataaattat ttcttttgta caaagggatg atgttatcaa
     3781 atcgatctgt tcttctatct tcttgatact gatcaaaaaa tttcatttcg actgaaaata
     3841 tttcgcttat aaactgtaaa cgaatacttt gtttagacat tatagtcgct agactgacta
     3901 gatgattact caaaacgacg tccagaatac tctttacttt gcttggtttt ttaacaaaaa
     3961 tttgattatc caaaggttca atcattttgt aacctttttg cgcaatttga cgataaaagt
     4021 aagaatgttg ctttggagtc aataatccta acttaaaagc tcgatactct aaagcctgta
     4081 tcgaaacatt caaatccgac ttcaataaaa tataactatc aggattgctg acacgcttgc
     4141 caaccctctc ttcaaatttg actaaaaact cttcttttgg caataaaaaa catgatgcaa
     4201 aataatttgc ttcttgctcc aaacgatcgc catcttcatt catatcttta tatttatgta
     4261 aaagaatatg tcctagctca tgagctaagt caaaatttcg acgtacagat gatttattcg
     4321 ttcccaacac aatataaggt cttcccaatt ttgaccatgc gctataagca tcagcttggc
     4381 cattaattaa tcgttccacg atatagatgc ctgagcgttc taatttataa agcaaatcat
     4441 gattatcttt tgaaatacct aatttttccc tggcataaag agccaattcc tcaatggatt
     4501 ctcccttatg ataagattca ctcactacat tacttaggtc atgaattgta atattaggta
     4561 taattacaaa actttcaaaa taatcaatca aactatctac cttatgtaaa tacatagttt
     4621 gaatatctat tgttttccgt gttgctaggt ctgcatttct aaaggcaatt acagaagaat
     4681 caaatcgaat gctctcttct tcctgttcaa aataagttaa atcaacatga aattggttgg
     4741 ccaaatgcat tttggttgat aatttaggtt tcgtttcgtt ggactcaaac tgccaaatgg
     4801 cttgttccgt taaattaatt ctctgagcta attctgctct acttaaacca tttaacagcc
     4861 gtaattcttt caatacccga ccattaaaca tttacatact ccttactact tttgaccttc
     4921 ttgtttttct attcttggaa taatttcaaa atcttctgtt tccgataatt ctgaaaaatt
     4981 aggaatatct tgatatttag cttcttcgaa atggtacgaa cttgattgaa tatactcaga
     5041 caaatcttga atcaagtgta actgaccagt tcgtgcatca ggcataacaa catctacaga
     5101 tataatattg ttttctgagt ccgcctcata agttaaaatc ataaattttt cgatattcga
     5161 atttttagta gcttgttcaa tttcttgaat catttcatca gaaactaact ccatctgaat
     5221 tggaaaggaa tgactatctt catcattttt gtaggaagaa tgttgattaa gataaagtgt
     5281 attcatctga gcatattcaa ataagtagcc actcttattt ttttgtacca aaggaaattg
     5341 gttcgtaagt cgcttcttac cctttataat taacaatact ttcccatatt tttctgtatt
     5401 tgtttcaaat tctaaatatc cccaagtctg tcctgctaat tgtaatttat actcaaacaa
     5461 atctgctgat gcaaatgcag tatcaatatg attaggtcgc gtccatgcat aaccattcga
     5521 cactatcatt gtctctcttt tttctagacg ttcatctaca taatcttttt gccctttcat
     5581 caaagtatct acaatttttt gtgcctcaag cgaatcaaag agatcctgat tcaacataat
     5641 tcttcctcct ccaaatactt tttaatgaat tatatcattt tcttaaaga
//
LOCUS       DAVKBC010000070         5629 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVKBC010000070 DAVKBC010000000
VERSION     DAVKBC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5629
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.070"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            44..232
                     /locus_tag="VWX64_001915"
     CDS             44..232
                     /locus_tag="VWX64_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU9191325.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            294..1052
                     /locus_tag="VWX64_001916"
     CDS             294..1052
                     /locus_tag="VWX64_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9191326.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     ISEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            1110..1964
                     /locus_tag="VWX64_001917"
     CDS             1110..1964
                     /locus_tag="VWX64_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU9191327.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            2076..2960
                     /locus_tag="VWX64_001918"
     CDS             2076..2960
                     /locus_tag="VWX64_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU9191328.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            3123..4862
                     /locus_tag="VWX64_001919"
     CDS             3123..4862
                     /locus_tag="VWX64_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEU9191329.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGEFMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            5137..5592
                     /locus_tag="VWX64_001920"
     CDS             5137..5592
                     /locus_tag="VWX64_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191330.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         1888 a          833 c         1194 g         1714 t
ORIGIN      
        1 acaagtgtta cacctgtgat agaattaact tgaggtgatg aaaatggcaa ccgataaaaa
       61 tagaataatg attagcttgg atgataaaaa tctagagaaa cttgaaaatt tagtagaaga
      121 tgctagagat agaaggggaa tgcgactaac aaagtcccag gttattgaat tactcctaaa
      181 taccgttgat tatttcgatg atattatggg ggctatttac tcaaaaaaat aagagcaaaa
      241 ttgctattat tttttacaaa ttggtgtaac actagtgata taggagtgat gaaatggttg
      301 tttatattag acaaagtaaa ttaccaagtg aggtttcaat taataaatac aatgctcaag
      361 taggtgccta cttacaagga gaagaagtta ttttatatca atctttttct gaaataaaag
      421 agttaataag tgaagatata gttgtagatt atataatgga gactagagca ttactaaaaa
      481 tgatgggctt aaacgttccg gtttatgact atcctattga gcttaaagag ttttatggtc
      541 gaaagattta tgctggtatt ttaggagaga ttgtgaatat acctgataat tggggaaaat
      601 ttattaagcc taaagctggt tcaaaagtct ttactggaag agttgttaat ggaacccatg
      661 atttaatagg tattggtcta cctttcgact atcctatatg gattagtgag gttgtagaat
      721 tcatagctga atggcgttgt tttgtgttag atggtcgcgt attagatgtt cgaccctata
      781 caggtgatta tcatgcacaa tttgatgcaa gtgtaattga tgaagcgata tcatgttgga
      841 aagatgcgcc aatagcttat ggactagata tcggtgttac tcgcgatggc agaacacttg
      901 ttgttgaagt aaatgatggt tatgcattgg gaaattatgg cctatctcct ttaaaatcaa
      961 tcaattttca tagagctagg tggaaagaaa tggtaaaacc ctattttgaa aaaaatgaaa
     1021 tttttaaaat ccaacaggat gttattttct aaaataaata tggtagataa ccaatataaa
     1081 aagcatcaaa atgaacaagg aggaatctga tgcttggagc aattattgga gatattgtcg
     1141 gttctgttta cgaatggaac aatatcaaaa caaaggactt tcctttattt cggaaggact
     1201 gcttttttac agatgacacg gttatgacct gtgctgttgc agaagcaatt atgaatggtg
     1261 gacaaaaaga cgatttcatt gacgcgatga agaaatatgg cagaatgtat ccgaatgctg
     1321 attacggtgc tcggtttaat gcatggctaa acagcgataa ccgtgagcct tataatagct
     1381 ttgggaatgg atcagctatg cgtatttctc catgtgcttg gatcatggac tgtggttttt
     1441 atgcgaaaac tggtatgtgg ccatcatcta gaggacttac gagtctttct gcagaggtaa
     1501 ctcataatca tccagaaggt gtcaaaggcg ctatggctac agctgatgct atctttctat
     1561 gtcgttttta ctttggtggt tattgtagag agtacgagca atcaattaac gacaatccta
     1621 cagagtgtaa aagacgaatt aaggattata tagaaaaaga atacgattac aatctatctc
     1681 aaactttaga tgaaatccgt cctaactatc gttttaacga aacatgtcag gaaactgtcc
     1741 ctcaagctat tatcgccttt cttgaaagta gagacttcga agatgcgata agaaatgcca
     1801 tctcacttgg tggcgacagt gatactctcg cagcaatcac ttgtaacata gcagaggcag
     1861 cttacggtat tcctgattgg atcaaggata aggcctattc ttacttggat gaacccttaa
     1921 aggatgtagt taggcgatgg gaaaatagaa taaaagcgta ttaatctcca gtacgtcaga
     1981 tttctctttt ctgtattttc attgtataat aggattacat ttacttgcat acgacgaaat
     2041 gtaaacattt ctgtttaaaa ttaaggataa aatcaatgaa aaaagcaatg gtaattatca
     2101 accctacttc tggtggcgag aaggctttgg attacaaaga aaagctggag aataaagcaa
     2161 aagaatactt tgaatatgtt gaaaccaaaa ttaccgaaaa agcgctggat gcaacacatt
     2221 ttgctgaaga agcttctcgt gagcagtatg atgcagtggt tgtgtttggt ggagatggaa
     2281 ctgtcaatga agtcatttca ggtattgatg agagagacta cattcctaag ttagggatta
     2341 tcccaggcgg tacgggtaac ctcattacaa aacttttgga aatcaatcaa gacatcgatg
     2401 gcgcaattga cgaactggat tttgatttaa ccaataagat tgatatcggt aaagcaaatg
     2461 acaactattt tggttatatc tttagtatcg gttctctgcc tgaggcgatt cacaatgttg
     2521 aaatagagga caaaacaaaa ttcggtattt taacctatgc tgtaaatacc atgaagtctg
     2581 tcatgacaga tcaggtcttt aacattaagg ttgagacaga aaatggaaat tatgttggtg
     2641 aagctagcca tgttttggtc cttttgacaa attacttcgc tgataagaaa atctttgaag
     2701 aaaacaagga cggctatgcc aacattttga ttctgaaaga tgcctctata ttctccaaat
     2761 tatccgtcat tcctgattta ttaaaagggg atgttgtcgc aaatgataat atcgagtata
     2821 tcaaagcgcg taatattaaa atctcttcag atagtgaatt ggagtcagat gttgacggag
     2881 ataaatcaga taacctacct gtagaaatca aagtcctagc tcagcgagta gaagtatttt
     2941 caaaaccgaa agaggattag tatatagaga aagccttttt taaggctttt tgtatacttt
     3001 aaaagatagt tcctttaaca acggacattc cttgcaaata gtttacaaaa atagtatact
     3061 ggattcattg agtttgaaaa cgtttgcgta aaatttgaat gaatacttta ggagacaaat
     3121 tgatggaatt gagtgctatt taccataggc ctgagtcgga gtatgcctat ctttataagg
     3181 ataagaaact ccatattcga attcgaacta agaaagggga cattgaaagc atcaacttgc
     3241 actatgggga cccttttatc tttatggagg agttttatca ggatacaaaa gaaatggtca
     3301 agataacttc tggtacctta tttgaccatt ggcaggttga agtgtcagtt gactttgcac
     3361 gtatccagta tctctttgag ctcagagata cagaaggtca aaatattttg tatggcgata
     3421 aagggtgtgt ggaaaattct ctagaaaatc ttcatgcaat cgggaatgga tttaagttgc
     3481 cttatcttca tgagattgat gcctgcaagg ttcctgactg ggtttcaaat acggtatggt
     3541 atcagatatt tcctgaaagg tttgccaatg gcaatgctct attaaaccca gaagggactt
     3601 tagactggga ttcatctgtc acacctaaga gcgatgattt ctttggtggt gatttacagg
     3661 ggattattga tcatatggat tacttgcaag acttgggtat tactggacta tatctttgtc
     3721 ccatctttga atctacaagc aatcacaagt acaatacgac agattacttt gaaattgacc
     3781 gtcattttgg agacaaggag acctttcggg aactggtgga tcaagcgcat catcgtggca
     3841 tgaaagtcat gctggatgcg gtatttaatc atattggttc gcaatctctt caatggaaaa
     3901 atgtcgtcaa aaatggtgaa cagtctgctt ataaggattg gttccatatt caacaattcc
     3961 cagtgacaac tgaaaagcta gttaataaga gagacttacc ctatcatgtt tttggtttcg
     4021 aggactatat gcctaagcta aatacagcca atccagaggt caagaattat cttttaaagg
     4081 ttgcgactta ttggattgaa gagtttaata tcgatgcttg gcgtttggat gtggctaatg
     4141 agattgacca tcagttctgg aaggattttc gtaaggcagt tttagctaaa aatcctgatc
     4201 tttatatcct aggagaagtc tggcatacat ctcagccttg gctaaatgga gatgagttcc
     4261 atgccgtcat gaattatcct ttatctgata gtatcaagga ctatttctta cgaggaatta
     4321 agaagacaga ccagttcatc gatgaaatca atggagagtt tatgtattac aagcagcaga
     4381 tttcagaggt catgtttaat ctcttggatt cacatgatac agagcgaatc ctgtggacgg
     4441 ccaatgaaga tgttcaactg gttaaatcag ccttagcctt tctcttttta caaaaaggaa
     4501 caccgtgcat ttattacgga accgagctag ccttgactgg aggaccagat ccagattgtc
     4561 gtcgttgtat gccttgggaa cgtgtatcaa gtgacaatga tatgctgaac tttatgaaga
     4621 ggctgattaa aattcggaaa tacgcgtcag taatcatttc gcatggcaag tatagccttc
     4681 aagaaatcaa atctgatcta gtagctctgg aatggaaata cgaaggacgg atcctcaaag
     4741 caatattcaa ccaatcaaca gaagattatc ttttagagaa agaagcagta gcactagcaa
     4801 gcaattgcca agaattggag aatcagcttg tcatctctcc agatggattt gtgattttct
     4861 aaaaactagt tgatgaagat tatggtacat ttcatatctt atatagtata ataaggctag
     4921 ttactaaact tgtaaaggag aacttaaatg aattgtagag gacatgaaac aagacaaaga
     4981 attgttagag attttgaagt ttagcctaaa gcacatatta agctgttagc aaatcaacaa
     5041 aaacatagtg atgcaggagc aactattgaa gatgaatatt atgtatttat cgctgagagt
     5101 aaaattgatg gcaagaagga agttattcag tgttgcatgg gtgcggcaag ggatttttta
     5161 gaactaatta atcacaaagg gctacctctt tttaatccgc ttgtaggtga ttctcatgta
     5221 aataatagac aagaatatga caatacaggg agtggaaatt tacaacctga aaagtggaat
     5281 gaaactgcaa agcagcttta taatgttata atgtggttga ttattttatg gaatgctaag
     5341 ccggatacac ctttatttaa ttttaaagac gaagtaatta agtataaaac atatgagcct
     5401 tttgaaagca gtataaaaag agtaaatact actataaaga atggtagtaa agggaaaact
     5461 ctgactgaga tgattaatgg ctacagagcg gataacgata ttagagatga aatttgtaac
     5521 tttaatattc tgaaaaataa aattcgtgat atgaaagacc aacaaggaaa tacaatggaa
     5581 tcttactttt agttattgtt gaattttggg tattctataa aatatccta
//
LOCUS       DAVKBC010000071         5194 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVKBC010000071 DAVKBC010000000
VERSION     DAVKBC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5194
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.071"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            84..1259
                     /gene="mutY"
                     /locus_tag="VWX64_001921"
     CDS             84..1259
                     /gene="mutY"
                     /locus_tag="VWX64_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU9191331.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1314..2018
                     /locus_tag="VWX64_001922"
     CDS             1314..2018
                     /locus_tag="VWX64_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9191332.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2011..3360
                     /gene="vicK"
                     /locus_tag="VWX64_001923"
     CDS             2011..3360
                     /gene="vicK"
                     /locus_tag="VWX64_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU9191333.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3362..4171
                     /locus_tag="VWX64_001924"
     CDS             3362..4171
                     /locus_tag="VWX64_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9191334.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4262..4504
                     /locus_tag="VWX64_001925"
     CDS             4262..4504
                     /locus_tag="VWX64_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU9191335.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4506..4760
                     /locus_tag="VWX64_001926"
     CDS             4506..4760
                     /locus_tag="VWX64_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU9191336.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQINVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4807..>5194
                     /locus_tag="VWX64_001927"
     CDS             4807..>5194
                     /locus_tag="VWX64_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEU9191337.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLR"
BASE COUNT         1598 a          874 c         1169 g         1553 t
ORIGIN      
        1 atagaaaagt tatatactat ctattgaaaa tattataaat cagatacaaa gacaggtgaa
       61 accttctgtg ttatactaga gatatgttag atttgaaaga atacggtatc gtcatgtggc
      121 cggaggagaa agtcatttct ttccgtgaga aacttctcgc ttggtatgat gaaaacaaaa
      181 gagatttgcc ttggaggaga agtaaaaatc cttatcacat ctgggtatct gaaatcatgc
      241 ttcagcagac cagggtggat acagttatcc cttactacga aagatttttg gactggtttc
      301 caactgtcga aagtctggca actgcgcctg aggagagttt actgaaagct tgggagggct
      361 tgggttatta ttctcgagtt cgcaatatgc aggctgcagc ccagcagatt atgactgact
      421 ttggtggcca atttccaaat acctatgaag gaatttccag cttgaaaggg attggacctt
      481 acacagcagg agccatttcc agtattgctt ttaacttgcc tgagccagct gtagatggta
      541 atgtcatgcg ggtcttggcg cgtctgtttg aagtcaacca cgatattggg attccaagta
      601 atcgaaaaat ttttcaggca atgatggaga tcttgattaa tccagatcgt ccgggtgatt
      661 ttaatcaagc cttgatggac ttagggtctg atattgagtc tcctgtaaat cccagacctg
      721 aagaaagccc agtcaaggac tttagtgcgg catatcagaa tggaaccatg gaccgttatc
      781 caattaaatc tcctaagaaa aagccggttc ctatttatct taaagcctta gttgtgaaaa
      841 attctcaagg acaattttta cttgaaaaaa atgaaagcga aaagctcttg gcaggttttt
      901 ggcatttccc ctttatagaa gttgataact tttcgcaaga agagcagttt gacctctttc
      961 atcaggttgc ggaagaaagt gtgaactctg gccccagtcc agaagagagt ttccagcagg
     1021 actatgacct agatgttgat tggcttgatg tttgttttga tacagtccag catgttttta
     1081 gtcatcgaaa atggcatgta cagattgtag caggtcaggt gagtgacttc catgattttt
     1141 cagataggga agttcgttgg ctttcaccag aagaattcaa gaattaccca cttgccaaac
     1201 cccaacaaaa aatctggcag gcttatgcac aagccaactt agacagtagc caagactagc
     1261 tattgtgtct tctgactatt ttttggtata atagtagaga aaaaggtgaa catatgaaaa
     1321 aaatactaat tgtagatgat gagaaaccaa tctcggatat tatcaagttt aatatgacca
     1381 aggaaggtta cgaagttgta actgctttta atggtcgtga agcgctagag caatttgaag
     1441 cagagcaacc agatattatt attctggatt tgatgcttcc agaaattgat ggtttagaag
     1501 ttgctaagac cattcgtaag acaagcagtg tgcccattct tatgctttca gccaaagata
     1561 gtgaatttga taaggttatc ggtttggaac ttggggcaga tgactatgta acgaaaccct
     1621 tctccaatcg tgagttgcag gcgcgtgtta aagctcttct gcgtcgttct caacctatgc
     1681 cagtagatgg tcaggaagca gatagtaaac ctcaacctat ccaaattggg gatttagaaa
     1741 ttgttccaga cgcctacgtg gctaaaaaat atggcgaaga actagactta acccatcgtg
     1801 aatttgagct tttgtatcat ttagcatcgc atacaggtca agtcatcacg cgcgaacact
     1861 tgcttgagac tgtctggggt tatgactatt ttggtgatgt ccgtacagtt gatgtgactg
     1921 tacgacgtct gcgtgagaag attgaagata cgcccagccg accagagtat atcttgacgc
     1981 gccgtggtgt agggtattac atgagaaata atgcttgatt tactgaaaca aaccattttt
     2041 accagagatt ttatctttat cctgattttg ttaggtttca tccttgttgt gaccctctta
     2101 ttactggaaa atagacgtga taatattcag ttgaagcaaa tcaatcaaaa ggttaaagat
     2161 ttgattgcag gagattattc caaggttctt gatatgcaag gtgggtctga aatcaccaat
     2221 attaccaata atttgaatga cttgtcggag gttattcgtc tcactcagga aaatctagaa
     2281 caagagagta agaggctaaa tagtattctg ttttatatga cagatggggt tcttgcgacc
     2341 aaccgtcggg gtcagattat catgattaac gatacagcca agaagcaact ggggttggtt
     2401 aaggaagatg ttctgaatag aagcattttg gaattgctca agatagaaga aaactatgaa
     2461 ttgcgtgatt tgattaccca aagtccagaa ttgttgctag attcccaaga tatcaatggt
     2521 gaatatttga accttcgagt tcgctttgcc ttgatacgtc gagagtctgg ctttatttca
     2581 ggtttggtgg ctgttttgca tgatacgacg gagcaggaga aggaagaacg cgaacgaaga
     2641 ctctttgttt ccaatgttag ccatgagtta cggactcctc tgactagcgt aaaatcctat
     2701 cttgaagcct tggatgaggg ggctttgtgt gaaactgtag caccagactt tatcaaggtt
     2761 tctcttgatg agaccaaccg tatgatgcgc atggtgacgg atctcctcca tctttcacgt
     2821 attgataatg ctaccagtca cctagatgtg gaactgatta acttcactgc ttttattacc
     2881 tttatcctca atcgttttga caagatgaaa ggacaggaaa aggagaaaaa atatgagttg
     2941 gtgagagatt atcccatcaa ttctatctgg atggaaattg atacagataa gatgacgcag
     3001 gttgtcgaca atattttaaa taatgctatt aagtattcgc cagatggggg taaaatcact
     3061 gtcagaatga agacaactga agaccagatg attttatcca tttctgacca cggtttgggg
     3121 attcctaagc aggatttacc acgtatcttt gaccgtttct atcgtgtgga tcgtgctaga
     3181 agtcgtgcac aaggtggtac aggtctagga ctgtctatcg ctaaagaaat tattaaacaa
     3241 cataagggct ttatttgggc caagagtgaa tacggcaagg gttcaacctt taccattgtg
     3301 ctcccttatg ataaggatgc agtgaaagaa gaagtatggg aggatgaagt agaagactag
     3361 aatgagtgaa ataggcttta aatacagtat tttagcgtcg ggttccagtg gaaattcttt
     3421 ttatctggaa acctcaaaaa agaagctttt agtggatgca ggcttgtctg gcaagaaaat
     3481 taccagtctg ctagctgaaa ttaaccgcaa gccagaagac ctggatgcca tcttgattac
     3541 ccatgagcat tcagatcata tccatggagt aggcgttttg gctcgcaagt atggtatgga
     3601 tctttatgcc aatgaaaaga cctggcaagc tatggaaaat agtaaatatc ttggcaaggt
     3661 ggattcttcg caaaagcata tttttgaaat gggtaaaacc aaaacctttg gagatatcga
     3721 catcgagagt tttggtgtaa gccatgatgc agtcgcaccg cagttctatc gctttatgaa
     3781 ggatgataag agttttgtcc ttttgacaga tacaggttat gtcagtgacc gtatggcggg
     3841 cattgtcgaa aatgcggatg gctatcttat cgaggccaac catgatgtag agattttgcg
     3901 atcaggttct tacgcttggc gactcaaaca acgaatccta tctgaccttg gtcacctttc
     3961 taacgaggac ggtgctgaag ctatgattcg gacgctagga aatcgtacta agaagattta
     4021 ccttgggcat ttatctaagg aaaacaatat caaggaactg gctcatatga ccatggtcaa
     4081 tcagctggct caagctgatc tgggagtcgg agtagacttt aaggtttatg atacctcacc
     4141 agataccgca acaccattga cagagatata gaaagaacgc tgagaaggtg ttctttttat
     4201 attgactgaa cacctaaaaa gtaatacaat ggtgttacca ttaaaaaagg gagcacaaaa
     4261 gatgactact attacattaa aagtttctga agctgataaa acatttatga aagcaatggc
     4321 taagtttgaa ggagtttccc tttcggaact tattcgcacc aaaactcttg aagccctaga
     4381 agatgaatac gatgctcgtg tggcagattt agcctatcaa gagtatttag aagacttgga
     4441 aaaaggagtt gaacccatta cttgggaaga aatgatgcat gatttaggct tgaaggatga
     4501 ataatttgta taaattagtt ccaacaagac gtttcatcaa gcaattgaaa aaattggacc
     4561 gttatacgca gaagctaatt acaaactatt tacaaatcaa tgttttggaa gacccaagac
     4621 gacacggaaa ggctttggtt ggtaatcgcg ttggtcaatg gcgctataga attggtaatt
     4681 atcgagttat cgtacaaatt gtagatgatg aattagttgt tgctactcta gaagttggtc
     4741 atcggagaga tatttattga attaaagctg agtaataaca atatagaaag taaggagagt
     4801 aaaaatttga agaaaaaatg gttttttgca gattattatg atacaacaat tattttactt
     4861 gctttaatct ctgttattct ggtattactt ggatttgctg agatgattga tttggacaat
     4921 ccgccttata gtattattga tttagtaatc tggggtgttt ttgtaattga ttatagttgg
     4981 cgctttttta ttactaaaag aaaatggcgc tttattcttg aaaatatttt tgatttattg
     5041 gctattctcc ctttaaatgc tattttcaca gtttttcgat tagggcgtat ctttcgttta
     5101 gttaaactaa caaaattact gaaactgact cgtttactta gaataattgg acttacaggt
     5161 aaattagaaa gaaaaattag tagattctta cgga
//
LOCUS       DAVKBC010000072         5029 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVKBC010000072 DAVKBC010000000
VERSION     DAVKBC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5029
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.072"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..249
                     /locus_tag="VWX64_001928"
     CDS             <1..249
                     /locus_tag="VWX64_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two pore domain potassium channel family
                     protein"
                     /protein_id="HEU9191338.1"
                     /translation="ILSVVEEKSFSDSLWWALVTVTTVGYGDIVPVSLLGKWLAVLLM
                     LVGIGTIGMLTSALTNFFVKDNPDEQIKLDKLKDELSS"
     gene            complement(598..1584)
                     /locus_tag="VWX64_001929"
     CDS             complement(598..1584)
                     /locus_tag="VWX64_001929"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU9191339.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALSFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            1778..4246
                     /gene="gyrA"
                     /locus_tag="VWX64_001930"
     CDS             1778..4246
                     /gene="gyrA"
                     /locus_tag="VWX64_001930"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU9191340.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQTQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLVITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            4246..4992
                     /gene="srtA"
                     /locus_tag="VWX64_001931"
     CDS             4246..4992
                     /gene="srtA"
                     /locus_tag="VWX64_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU9191341.1"
                     /translation="MSQKKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIV
                     WNTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIP
                     ELEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDN
                     AKNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERII
                     VKGDLKETKDYSQTSNEILTAFNQPYKQFY"
BASE COUNT         1575 a          867 c         1109 g         1478 t
ORIGIN      
        1 attttatctg tagttgaaga aaaatccttc tcagatagtc tttggtgggc tcttgtgaca
       61 gtaactactg ttggttatgg tgatattgtt ccagtttccc ttttggggaa atggctagca
      121 gttttactga tgcttgtcgg tattggaaca atagggatgc taacaagtgc tttgacgaac
      181 ttttttgtaa aggataatcc agatgaacag ataaaacttg ataaactcaa agacgaatta
      241 tcgagctaaa gaatattaat agagaaacaa tctgaaaaaa tcgaagaact acattgaatg
      301 ataaaagact tagttgaaaa aatatcataa aggtgagaca aaataaaact tgattcgagg
      361 agaaatcaag taagtcttga cacaatagaa cgcatattat caggtataaa aacttgatac
      421 tatgcgtttt atagagaaat aaaataaaat ctgaacaaat caattaggaa tttaaagcat
      481 tttataacaa cgttttagag taatggggtg ctatttcaac ttcaacctac tataatacag
      541 aaaaaaatac agaaaaaaac aactccctga tgattcaagg agttgtctat agttaaatta
      601 gtttttagaa gcttcttgga attctggatt tttccatgct tcgtcaataa tagcttgcaa
      661 ttctttagca gatgcttgca ttttttgagt ttctgcatcg ttcaatggaa tgtttactgg
      721 acgaacgata ccatgtgcac caacaacagc tggttgaccg ataaagacat tctcaactcc
      781 gtattgacct tcttggaata ctgaaagtgg aagtactgcg ttttcatcgt caaggattgc
      841 tttagtgata cgagcaaggg ctactgcgat accgtagtat gttgcacctt ttttgttgat
      901 gattgtgtag gctgcatcac gaacaccttc gaacaattca atcaattcag cttcttgaac
      961 attttgagtg tctttaagga attcttcaag gtttacacca gcgatgttag cgtgtgacca
     1021 aacagcgaac tcagagtcac cgtgttcacc catgatgtag gcgtgcactg aacgagcatc
     1081 cacatccaat ttttcagcaa gtgcttgacg gaaacgagct gagtcaagtg aagtacctga
     1141 accgataacg cgttctttag ggaaaccaga gaatttccaa gttgagtaag tcaaaacgtc
     1201 aactgggtta gcagcaacaa ggaagatacc tttgaaacca gattcaacaa cttgagttac
     1261 gattgatttg ttgatagcaa ggtttttacc tacaaggtca agacgagttt cacctggttt
     1321 ttgaggtgca cctgcagtga tcacaacaag gtcagcgtct gcacagtcag agtattgagc
     1381 tgcatagatt tttttaggtg aagtgaagga aagggcgtga ctaaggtcaa gcgcatcacc
     1441 aacagctttt tcatgcaatt gtggaatttc gataattcca agctcttgtg caattccttg
     1501 gttaacaagt gcaaaagcgt aagatgaacc tacagcacca tcaccgacaa ggataacttt
     1561 tttgtgttgt ttagttgaag tcattgtttt aaacatctcc ttaattttat taggggattt
     1621 tccctagaca acttcattct atcactttta aaaaactttg tcacgaatat gccttatagt
     1681 tctctatgta aacgttttag tggtttagag gctgaaatag atgggaattt atggtataat
     1741 gttgttactt actaattgtg aaatgaggca tttattaatg caggataaaa atttagtgaa
     1801 tgtcaatctg acaaaggaga tgaaggcaag ttttatcgac tacgccatga gtgttatcgt
     1861 agcgcgagct cttcctgatg ttcgagatgg cttaaaacct gttcaccgtc gcattctcta
     1921 cggaatgaat gaattgggtg tgaccccaga caaaccccat aaaaaatctg ctcgtattac
     1981 aggggatgtc atgggtaaat atcacccaca cggggattcc tctatttatg aagccatggt
     2041 ccgtatggct caatggtgga gctaccgtta catgcttgta gatggtcatg ggaattttgg
     2101 ttccatggat ggagatagtg ctgccgctca acgttatacc gaggcacgta tgagcaagat
     2161 tgctctggaa atgcttcgtg atatcaacaa aaatacagtt gatttcgttg ataactatga
     2221 tgccaatgaa cgggaaccct tggtcttgcc agcgcgtttt ccaaaccttt tggttaatgg
     2281 agcaactggt atcgcggttg ggatggcaac caatattcca cctcataatc tgggtgaaac
     2341 cattgatgca gtgaagttgg tcatggataa tcctgaagtg actaccaagg acttgatgga
     2401 agtcttgcct ggaccagatt ttccaactgg tgctcttgtc atggggaaat caggtatcca
     2461 taaggcttat gaaacaggta aaggttcgat tgtcctacgt tctcgtacag agattgaaac
     2521 gactaagact ggtcgtgagc gcatcgttgt aacagaattt ccttacatgg tcaataaaac
     2581 caaggtgcat gagcatattg ttcgcttggt tcaggaaaaa cgcattgagg gtatcacagc
     2641 agtacgtgat gagtcaaacc gtgaaggtgt tcgatttgtt attgaagtca agcgcgacgc
     2701 ctcagccaat gttattctca ataacctctt caaaatgacc caaatgcaaa ccaattttgg
     2761 tttcaatatg ctcgctatcc aaaatggtat accgaaaatt ttgtctcttc gtcagatttt
     2821 ggatgcttat atcgagcacc aaaaagaagt ggttgttcgt cgtacacgtt ttgataagga
     2881 aaaagcggaa gcgcgcgctc atatcttaga aggtctcttg attgcgctag accatatcga
     2941 cgaagtgatt cgtatcatcc gtgctagtga aacggatgcg gaagctcaag ctgagttgat
     3001 gagcaagttt aagctttctg aacgtcaaac tcaagctatc cttgatatgc gtcttcgtcg
     3061 tttgacaggt ttggaacgcg ataagattca atctgagtat gatgacctct tggctctgat
     3121 tgcggattta gcagatattc ttgctaagcc tgaacgtgtt tctcaaatta tcaaagacga
     3181 attggatgaa gttaaacgta aattttctga taaacgccgt acagagttga tggttggaca
     3241 ggtcttgagt ctcgaggatg aggacttgat tgaagaatcg gatgtcttga ttaccctttc
     3301 taacagaggc tacattaagc gtttggatca ggacgagttc actgctcaaa aacgtggggg
     3361 tcgtggtgtc caaggaacgg gagtgaaaga tgatgacttt gttcgtgagt tagtgtcaac
     3421 tagcacccat gatcatctgc tcttcttcac aaacaaggga cgtgtctatc gtcttaaagg
     3481 ttatgaaatt cctgagtatg gtcggactgc caaagggcta ccagtagtca atctcttgaa
     3541 attggatgaa gacgaaagta ttcagacggt tatcaatgtt gagtctgatc gcagtgatga
     3601 tgcttatctc ttctttacaa cccgtcacgg tattgtgaag agaaccagtg ttaaggagtt
     3661 tgccaatatt cgtcaaaatg gtctcaaagc gctgaattta aaggatgaag atgagttaat
     3721 caatgtcttg ttggcagaag gagatatgga tattatcatt ggtaccaagt ttggttatgc
     3781 agttcgcttt aatcaatcag ccgttcgtgg tatgagccgt atcgccactg gtgtgaaagg
     3841 tgttaacctt cgtgaaggag acacagttgt tggtgccagc ttgattactg atcaagatga
     3901 ggttcttgtt atcacagaaa aaggatatgg taagcgtaca gtcgctactg aatacccaac
     3961 aaaaggtcgt ggtggtaagg gaatgcagac agctaaaatt accgaaaaaa atggcttgct
     4021 ggccggtctt atgactgttc aaggggatga ggatttgatg attatcactg atacaggtgt
     4081 catgattcga accaatcttg ccaatatttc acaaacagga cgtgcaacta tgggagttaa
     4141 agtaatgcgc ctggatcaag atgctcagat agtgactttc acaacggttg cggtggcaga
     4201 aaaagaagaa gttgggacag aaaacgaaac agaaggtgaa gcataatgtc tcaaaaaaaa
     4261 aataataaaa agaaaaacaa gcgaaaaaat ttgctgacaa atatcctagc aggatttctg
     4321 atattactgt cactggcttt gatttttaat actcaaattc gaaatatttt catagtctgg
     4381 aataccaata agtatcaagt tagccaggta tcaaaagaaa aattagaaga aaatcaggat
     4441 acagaaggca attttgactt tgattctgtc aaagctatct cttcggaagc tgttctaact
     4501 tctcaatggg atgctcaaaa attaccagtt attgggggaa ttgcaattcc tgaattggaa
     4561 atgaatttgc cgatttttaa aggacttgat aatgttaatc tcttctacgg agctggtaca
     4621 atgaaacgcg agcaagtaat gggagaagga aattatagtc tagctagtca ccatatcttt
     4681 ggtgttgata atgctaataa aatgttattt tctcctttag ataatgctaa aaatggcatg
     4741 aagatttatc taaccgataa aaataaagtt tatacttatg aaatacgtga agtcaaacgt
     4801 gtgacaccgg atcgtgttga tgaagttgat gatagagatg gggtcaatga aatcacatta
     4861 gtaacctgtg aagaccttgc tgctacagaa cgtattattg tcaaaggtga tttgaaagaa
     4921 acaaaagatt attcacaaac atctaatgaa atcctaacag ctttcaatca accatataaa
     4981 caattttatt aatacaaatc agtgaaatca tggatttcac tgatttttt
//
LOCUS       DAVKBC010000073         4983 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVKBC010000073 DAVKBC010000000
VERSION     DAVKBC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4983
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.073"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(132..1547)
                     /locus_tag="VWX64_001932"
     CDS             complement(132..1547)
                     /locus_tag="VWX64_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9191342.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLKRYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRY
                     KKMSFTWYKEVIESNGESLFK"
     gene            complement(1560..3398)
                     /locus_tag="VWX64_001933"
     CDS             complement(1560..3398)
                     /locus_tag="VWX64_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9191343.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTLAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3416..4255)
                     /locus_tag="VWX64_001934"
     CDS             complement(3416..4255)
                     /locus_tag="VWX64_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU9191344.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4556..4738)
                     /locus_tag="VWX64_001935"
     CDS             complement(4556..4738)
                     /locus_tag="VWX64_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU9191345.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIASELVAGLR"
     gene            4797..>4983
                     /locus_tag="VWX64_001936"
     CDS             4797..>4983
                     /locus_tag="VWX64_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9191346.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDL"
BASE COUNT         1688 a          948 c          656 g         1691 t
ORIGIN      
        1 taacaaaatt aaattaatta atccccctat aaaataaaga agtttagaat ttaatgtctt
       61 ccaaacttct ttattccata tttaatgaaa tgctgcctta accgtgataa tagctagtca
      121 tcaataaaaa actatttgaa taaggattct ccatttgatt caatcacttc tttataccaa
      181 gtaaaagaca ttttcttata tcgatttaat gtaccacttc catcatcgtt tcgatcaaca
      241 taaatgagac cgtacctttt agaaagttgt gcagtggaca tagaaacaca gtcaatacat
      301 ccccaagacg tatagcccat aatttccaca ccatcttgta gagcttcagc tacttgcaat
      361 aaatgttctt tcatatactg aattctataa tcatcttgga ctgttaagtt attaaattca
      421 tcttttatta gttgatcttt agcacctaat ccgttttcca ctataaataa tggaatttga
      481 taacggtcat aatatctatt taaaattata cgtagtccaa ttggatcaat ttgccatccc
      541 cactcagaag actctaaata aggatttact aagccaccaa taatattccc ttctcctgaa
      601 ttatactgtg ttggaagagc agattgagtc acactcatgt aatagctaaa ggataaaaaa
      661 tctacggtat aattttttaa taactctgca tcttcagctg caaactctat gttaatgtca
      721 tgttccttaa aatatctttt tgcataattc ggataataac ctctaacatg cacatctgaa
      781 aatagataat ttagattctc atactcatga gtcgcccata catcttttgg atttggagtc
      841 attggataag ctggcatagc taataccata caccccacct taaactctga attaatctca
      901 cgagcaattt ttgtaaccaa actcgaggcg actaattcat gatgtatagc ttgatataat
      961 tcttgtttcg aaagattctc cttaggtata tctattcctc cactagtaaa cggtaattcc
     1021 aaaacagagt ttacttcgtt aaatgtaagc caatatttaa ctttatcttt ataccttttt
     1081 aaaactgttc gagcaaattt ttcataaaaa tgaatcattc tcctatcaat ccatccatga
     1141 tattttcttg ctaaatataa tggagtctca tagtgtgaaa gagttacaag tggttctatc
     1201 ccgtgagcat gtagttcatc aaataattca tcataatatt tcaaaccagc ttcgttaggt
     1261 tcttcctcat ctccttttgg aaaaattcta ctccatgcaa tagaagtacg aaaaacatta
     1321 aagcccattt cagaaaacaa ggatatatct tccttatatt tatgataaaa atcaatacct
     1381 atcaatttta agttatcttc tgtaggattt tctgttgctt ctcctaatcc acctttgggt
     1441 aacacatcct gaactgataa gcccttacca tcttcattat atgctccctc tacttgatta
     1501 gctgcaacag ctccacccca aagaaaatca tctggaaaaa tggtcataac tttcctccat
     1561 tataatatta ccagtaattc cttagaatgc tcgattgtct gattattagg taatactaat
     1621 acatctagaa aatcattggt attcgttaca attactggtg taactgtttc gtagccttta
     1681 gtcttgatta aattcaagtc catttcaaaa atcaactgat ttttgaaaac tctgtctcct
     1741 tcttctacat gactaataaa accttgacct tttagctcaa cagtatctaa tccaatatga
     1801 attagtaact caacaccctc atcactcttc aatccaattg cgtgcttagt cggaaaaata
     1861 tttgtaattt tcccatcaaa tggtgcataa accttacctt cacttgggat aatcgctact
     1921 ccgtctccaa ttagtttatc tgaaaatgtt ttatcctgga catcgcttaa cggaatgatt
     1981 tctcctgata taggagaaaa tatcattttt ttatttgaaa ctccagcttc aacttctaaa
     2041 ttgctagaac tctcttcttc atcgattcca aatatataag ctaatacaaa ggtaataaca
     2101 accgaaatga ccgccacaat taaagcattt acaatatttg atggcacatc agaataaata
     2161 aattgaggca acgctatcaa agatgggaca gcaaatagat atgctttaac actagtaaga
     2221 cctgcaaata atcccgctaa tccaccacca atcatagctg cataaagcgg ttttttatat
     2281 tttaaagtca caccatataa tgcaggttcg gtaatccctg caagtaaggc tgagaaacct
     2341 gctgcaaaag caatttgttt tgtattatta tttttactct ttaatgcaac agccatcgaa
     2401 gcagcccctt gagctaagtt tgaccctaac attgctggaa gaattaatac gtctggagta
     2461 gcaatagatg ccgccaaaaa aataggtgca aaagcccaat gcattccagt cataacaata
     2521 aatggcataa tagcaccaag aatagctaat gtaagccatc cagctacacc atacatttgc
     2581 ccaactagat ttgataatcc ttcaccaaca attactccaa taggtccgac tacaactaag
     2641 gcaatacagc ttgatactaa taatactagc gtaggttgca aaaaactctt agtaatagct
     2701 agtgttaatt tagcaattat tttttcaata tatttcatca accaaaccat aataagaatt
     2761 ggaacgactg atgaaccata actagctggt gtcacaggtg caccaaataa actaagagga
     2821 ttccctgatt gcaccatttg aacaaaattt ggatggagaa gtacacctgc tacagacata
     2881 gctaatgtag atgttacttt taatttttgt gatgcagaat aagctaataa cagcggtaag
     2941 aaataatatg gagcatcccc aaaaaatgtc aaaaaagcaa tagtctgaga atctgattgc
     3001 aatataccaa gcattggtaa aatgattacc aagactttca acatacctcc ccctaacatt
     3061 gctggaatga ttggagtcat ggaaccagcg atatactcaa tgattctttc taaaatattc
     3121 cctttgtgcc cttgaacaac tgaatcggat tcaaaattgc caagtttaac gaattcttta
     3181 taataattag ctacatcatt accaagtata atttgatatt gtccattctt tttcataata
     3241 cctattacac ctggtatctt cttcacatca tcatcattga ctaaattttc atcttttaat
     3301 tctaatctta aacgtgttac acaatgggta actctattga catttttttc acctccaatt
     3361 acatcgagga ttttttgtac cgtatcttta taactcatgg tattctccta ttctattaat
     3421 ctaaattttt tgttaagcga cgaatatgag ccatcaaata aactaattca ctagaagtca
     3481 gcaaataatt gtactcagtt tgtataaaca ttgccacctg ttcaccacat tcatattctc
     3541 taggatattt atttttcatt aatgctaaca agtcttcatc atcatcgtca caataagttg
     3601 tattttcaac caagcgatgg gcaaataatt ttatatgagt tatgaatcta taataatcaa
     3661 tagaatcttg gttaaactca gtacaataga aatcttgaat gattttctca attcccataa
     3721 ttatttcagt gattttatac gactcttgaa aattattttc taaattagca ttaacaaaat
     3781 gtagcgctat gaatgcagct tcgtcaattg gaagttcaat acctaactct ttttttatta
     3841 tttgtaaagc ccttttccca agctcaaatt cttctttata atatttcgat atttcccagc
     3901 gtaggggatt cgaaataata actccttctt tataacgttc tatactcgaa gaaatatgat
     3961 ccgttagatt tatatagata atctcatcaa aattattacc taatgttatt ttacctagat
     4021 taattatttt ttcggtgatg tacaccaact ccaaaggaac gttaataaac atctctgtaa
     4081 aacgggtcat attatctcta tttttgagaa aaaaactttt ctcaatatca attggattta
     4141 ctttatctcc aatttttctt ccaaaagcta ttccccttcc aaaaagaaga atatcgatat
     4201 cttttttact ttgcgcaatt acggcattgt ggtttagtat tcgttttatg atcataaaat
     4261 ttccctttta aaataaaagg aacctactta aaaaacatca agaaacttct tctgatgtga
     4321 ttaaataggt tcctgctcac ttgtattagt gataacatcc ttttatttca atttttaatg
     4381 gtgacatgaa gcttaaataa ttaataactc tgtaaccgtt tttattttat gatatttcaa
     4441 tctatttgtc aagtacttat aaaaattttt ttattttgtg tgattcgaat gtgataatgg
     4501 caacagtctc actaaagaaa tgaaaatcat acatagaaat ttttaaaaat tttctctatc
     4561 gtaaacctgc cactagttca gaagctatac tagctgattc caaacgtaat atggtcatct
     4621 catctacctt ccctaataat ggcattgcac cataccaaac aatagtctta ttcaccaaaa
     4681 gaataggcgt tactattttt gattgagtaa aagacacttt aattttctgg ctcttcaact
     4741 gtgaactgca ccccaaaagt tagacagaaa aaatctaact tttggggtgt tttagtatga
     4801 aactaactta tgatgataaa gttcagatct atgaacttag aaaacaagga tatagcttag
     4861 agaagctttc aaataaattt gggataaaca attctaatct taggtacatg attaaattga
     4921 ttgatcgtta cggaatagag ttcgtcaaaa aaggaaaaaa tcgttactat tctcctgatt
     4981 taa
//
LOCUS       DAVKBC010000074         4560 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVKBC010000074 DAVKBC010000000
VERSION     DAVKBC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4560
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.074"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            31..1092
                     /locus_tag="VWX64_001937"
     CDS             31..1092
                     /locus_tag="VWX64_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9191347.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTGFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNELKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            1109..2113
                     /locus_tag="VWX64_001938"
     CDS             1109..2113
                     /locus_tag="VWX64_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191348.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSETQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIEEKVTMYINPRDIMQF
                     "
     gene            2125..3819
                     /locus_tag="VWX64_001939"
     CDS             2125..3819
                     /locus_tag="VWX64_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9191349.1"
                     /translation="MRKSLNWKDCLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEADKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIAAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            3821..4522
                     /locus_tag="VWX64_001940"
     CDS             3821..4522
                     /locus_tag="VWX64_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU9191350.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSLEG
                     YNRLLIYLNTSGIKILEIQNGIGNLDEERQLNKIKSTKVSCYLSLKLNENFEHLKLME
                     EMHNIAGVIYVEEIR"
BASE COUNT         1529 a          643 c          844 g         1544 t
ORIGIN      
        1 aataaaaaat aataataaag gagaactatc atgttcaaaa actttaaaaa gattgcattc
       61 acttcttcac taattttact tgctgcttgc tcaaacaatg cttcaaatac aaatcagtct
      121 actgatgaag gaagtgttga taaatctcaa gaaattgtaa tctatacaaa ttcggcttct
      181 aatggacgtg cagattggtt acaaactaaa gcatcagagc aaggatacaa tctccgtttg
      241 gtagatattt caggtggaga actagctgac cgtttgattg cagaaaagaa taatgctgtg
      301 gctgatatgg taattggatt aaataaatta gaatttaacc gtattaaagc tgaaaaactt
      361 cttgtaaaat actcaccaaa atgggctgat gaagtagata gctctttggg agattctgaa
      421 gggtattatt caccaattgt aaatcaacca ttagttttga ttggtaataa agatgctaaa
      481 atgccatccg actggacagg ttttactgat tcatcttata aaggtaaata tggtatttca
      541 aaattaagta caggtacatc taagaacatc tttgcaagta ttgtttcgag atataaagat
      601 gaaaaaggtg agttaggaat atctgatgaa ggttggaaag ttgcaaaagc ttaccttaaa
      661 aatgcacacg tttatgcaga aggtgaagac tatatctctt caattatgga taataataat
      721 gagctaaaat atagtatgat gtggggatct ggtgttctac aaaatcaaaa agaacgtgaa
      781 tataaattcc aagtaatgtc accaaaagtt ggtgttcctt atgtaactga acaagttggg
      841 attttaaata caagtaagaa gcaagcatta ttaaaagaat ttgtagattg gtttggctct
      901 tcagaacttc aaaaagaatg gtctgataaa tttggttcaa ttccagctaa taaaaaagct
      961 ctagagcaag caaaagatga actcaaacag tttgctaata gtgttaaacc acaagaactt
     1021 gactgggaat ttatcgggaa aaacatcgat tcttggattg aaaaagcaca gcttgaattt
     1081 gttgaacaat aatagttagg attaagtgat gattacattt aaggatattc aaattaagta
     1141 taatgatttt attgccatcg ataatctcaa tttaacaatc aatgagggag agtttttcac
     1201 atttttagga ccaagtggtt gtgggaaatc aacaactctt cgtgcactag ttggattttt
     1261 ggagccttca caggggcaaa tactagttga taatcaagat attacgaatt tagatccaga
     1321 aaaacgcgaa attggtattg tgtttcaaag ttatgcatta ttcccaacaa tgactgtttt
     1381 tgataatatt gcttttggtc taaaagttaa aaaagtttct cctgaaatta ttaaagctaa
     1441 agttcatgaa attgcgaaaa aaattaatat ctcagacgag caactaaacc gaaatatttc
     1501 tgaattatca gggggacaac aacagcgtgt agctttagca cgtgcattag tattagaacc
     1561 aaaaattctt tgtttggatg aaccgttatc aaacctagat gccaaactac gagtttcgtt
     1621 gagaaaagaa ttgaaacgat tgcaaaaaga actaggaatc actactcttt atgtcacaca
     1681 tgatcaagaa gaagcattaa cattatcaga taggattgct gtgtttaata atggatttat
     1741 tgagcaagtt ggcacgccgt atgatattta taatcaatcc gaaactcaat ttgtctgtga
     1801 ttttattggc tcaatcaata aaattagcca agaagttctt aaaaaattac aaggcgagaa
     1861 taaatacttt aaagaaactg aaggatacat acgcttagag cgtgttaagt tagagaaaac
     1921 ttcacctcaa gatttatcta taacaggggt aattagtgat attgagttta atggtgtact
     1981 tattaagtat aaagtagact tgtcgaatag tgaaagtatt catattatcg aaaagaatga
     2041 tggactatca cgtcatataa tcgaagaaaa agtcactatg tacattaatc cgcgtgatat
     2101 aatgcaattt taaggagatt gtgcatgaga aagagtctaa actggaaaga ttgtctcata
     2161 agattaggag ttttatggct aatctttgcc ctgattattt atccaaatat tgaacttttg
     2221 tctggagtgt tttataaaaa tggttcattt actctagagg cattcaataa gattatacac
     2281 tctcagagag cgatgagtag tatatttaat agctttattt tggcgatttc aatggtcttt
     2341 actgtaaata ttgttgggac attgattgtt ctactcacag agtactggga tattaggggt
     2401 tcaaaaatac ttaaattagg ttatatgagc tctctagtat atggaggaat tgtattagcg
     2461 acaggatata aatttgttta tggcgctaat ggtcttgtaa ctaaaacgct ctcaagtata
     2521 attccaggtc ttgcccctaa ctggtttcaa ggatttggtg cagtattgtt tattatgaca
     2581 tttgcttgta cctcaaatca cataatgttt ttaacaaatg cagttcgtag tgttgattat
     2641 catacaattg aagcagataa aaatatgggt gcaagtcctt taaaagtttt ctttagtgtg
     2701 gtttttccaa cttttaaacc tacgttattt gccttaacca tcttaacttt tttgacaggt
     2761 ctttcagcag tttctgctcc tttgatagta ggggggaaag attttcaaac tattaaccca
     2821 ttgattatca gtttcgctaa aactacaagt tcgagagatt tagcagcttt actagctatc
     2881 atgttaggtt tagcaactat tctattattg acacttttga atcatgtcga aaaaggaggt
     2941 aattatgtat ctgtttcgaa aaccaaggct agtattaaga agcagataat ttcttctcca
     3001 ttatggaata ctcttgctca cattgctgcg tatgtattgt ttgcaatcta tatgttacca
     3061 atagttttga taattctata ctcgtttaca gactcgttga cgatcaagac gggaacttta
     3121 gatctatcta aatttacgtt agcgaactat gctaatttat ttacagatgc tcaatcattt
     3181 cgtccttacc tagtcagcgt tgtttatgca attttagctg cggtaattgc tacaattata
     3241 gcaatagtaa tttcacgtat tgtacataaa aacaagagta agttcgataa attctttgag
     3301 tatggtgcac tgataccatg gatattgcca ggtacattga ttgcactagg attaatgttc
     3361 acttataata tacctcattt aatactattt aatttagttt tagtaggaac agtaattatt
     3421 ttacttattg catatactat tcaaaaatta ccattttctt atagaatgat tcgggctgta
     3481 tttttcagta tagataatga tatggaagaa gctgcacgta gtatgggtgc atctagtttc
     3541 tacactatgg tgcgagttat tataccgtat attttaccag tcgtattatc agtagttgtg
     3601 ttaaacttta attctttatt atctgactat gacttatctg tattcttgta ccatccactt
     3661 ttccaaccat tgggaatcgt tattaaacag tctactgatg aaacagcaac tttaaatgca
     3721 caggcaatga tgtttgttta ttctgtaatt ttaatgatta tgtctagtgc agctctttat
     3781 ttatcaagcc tattccaagg taaacgaggt aagagataat atgaatcttt catacgaact
     3841 gagtatttgg gaaatacttc ttaggtgctt tttagcgatt cttttcggtg gcattgttgg
     3901 ctatgagcga ggagtcaaaa accaagcagc agggattaga acctacttac tagtttgttt
     3961 gggaacttgt gttgtaatga tgacaaatca gttcatcact agtcgttatg gtagcggtga
     4021 tcctagtcga atgggagccc aagtaattag tggcttgggt ttcctagggg caggaacaat
     4081 catggtaact aatcaaaaag ttaaaggttt aacaacagca gctggattat ggtcttcagc
     4141 aactattggt ttagctatag gcattggttt ttatgaaggt gctattttag ccggagttgt
     4201 actcatagca gttttaactc tatttactcc tcttaaagat tatttaaact cgaaaactaa
     4261 aattgctgat tactacttgg tttttagttc tttagaaggt tataatcgtt tacttatata
     4321 tttaaataca tcgggtatta agattttaga aattcaaaat ggtataggaa atcttgatga
     4381 agaacgtcaa ttaaataaaa ttaagtcaac aaaagtgtcc tgctatttat cattaaaatt
     4441 aaacgaaaac tttgaacatt taaaattaat ggaagaaatg cataatattg ctggtgttat
     4501 ttatgttgaa gagattaggt aagggtgact ttgtctaatt ttttctatat ttctaatcgg
//
LOCUS       DAVKBC010000075         4501 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVKBC010000075 DAVKBC010000000
VERSION     DAVKBC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.075"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(147..1997)
                     /locus_tag="VWX64_001941"
                     /pseudo
     CDS             complement(147..1997)
                     /locus_tag="VWX64_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863411.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(1984..2349)
                     /locus_tag="VWX64_001942"
     CDS             complement(1984..2349)
                     /locus_tag="VWX64_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU9191351.1"
                     /translation="MVYRYRTNLKKVFLTDPELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSY"
     gene            complement(2359..2718)
                     /locus_tag="VWX64_001943"
     CDS             complement(2359..2718)
                     /locus_tag="VWX64_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191352.1"
                     /translation="MGQEIKLIRKQFRSTRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            complement(3550..4002)
                     /locus_tag="VWX64_001944"
     CDS             complement(3550..4002)
                     /locus_tag="VWX64_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191353.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            complement(3930..4501)
                     /locus_tag="VWX64_001945"
                     /pseudo
     CDS             complement(3930..4501)
                     /locus_tag="VWX64_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1319 a          864 c          641 g         1677 t
ORIGIN      
        1 tgcaaaagaa agcgcttcta tttttatttt acaatttttt aatcctattg tcaaaaatta
       61 tttgtgctta aaccatatga gtgtgctcca tgtattgcag ttccttaaat caagcataat
      121 ccagcctttc tagctttatc cctcctctaa aatttgtcaa ttacgaaaac atctttttcc
      181 atatttaacg tgcttacaaa aatttctaat cttattgctc ttttctcaaa ctcataaaga
      241 taatagtcta agttttcttg caatactctt atttcttcgt tcacattttc taatgaagtt
      301 gattctgtta agttcagttt tgaaaagtca tacctggcta attttctagt ctcatgatct
      361 tcactcttca aattgataag gacttccgcc atcttgttta aggtggcgat tttttcttgg
      421 gtttcttcta gcttcatatc aatctctgca atttctaata caagctcatc tttgatttct
      481 tggtattgtt tgttcgtgtt agatagttca atcataagat taatttcaga aatcttctct
      541 tgaagacttt ttaaagttgg tcgtctatag gggagttttt ggctatcgtt gctcaattgt
      601 ctgattaagg tcctaccctt gatgaaacaa ttattatcca tgttttcttt attatagaca
      661 aagtaagaag acgtttctcg aatgtagact ttatattttt tatgattttc ttcttccata
      721 atatccaatt gatagttggg aatgaaaata agaccgctct gtttgacacc gaaagacacc
      781 ttgatataga cgcccttatc aactagcttc tctatttggt tctctgcaag ttccacttca
      841 aattcacgaa cggtatctca tttttcctta aatgtcttaa aggcttcctc aatctcttca
      901 gtggatactt tatccttatc tcgttcttct tggaaagcat ggtactgttc ctgtaaattc
      961 tctaatcctt ctgaagcaac gacttcctta tttttaaaat aatcttgaaa aaatttgaca
     1021 tcatataatt tcttatcact tattttttga tgacccaaac ttatcttttg attattttct
     1081 tccaggataa aagttacatt tttttgtttt aagtcaatgg ttagattcaa ttcttttgct
     1141 tttgttatta aatcttctaa agaattgaca cggtttaaca aaaattctaa acgactttca
     1201 atctcttgct tagcaaaatg cgttctaaaa aattcttcat catatagatc tcgtttgctg
     1261 agttggcgcc ctcgaattgg ttttatcatc gttctatctg tcatcaaaaa acggctatgc
     1321 ttttgactaa aatcaatctg aacatgcaac tgctttgctt tctctaaaaa atcatcaaac
     1381 gatttagatt gctgaagcaa aaaataaaga cgttgtttca attcaaattt atgactagat
     1441 tccttatatt ttttataatc tcgataggaa taacgtttct caataatttt tgcaccagtc
     1501 attttagaaa tacggtctga aatcatacgg aggtttcgtt ccaaggcata gttccatatc
     1561 aactttttat ctgaattgcg gtcaatagcg ttgattagga tgtgattatg aacatgatct
     1621 ttgtctgtgt gagttgctac gataaactta aaacgacctc ctgtcaattc catcatggtc
     1681 tcataaccaa tgcggttaat ttcttcaggt gtcagattat cttcaggaga aaatgattgg
     1741 atgagatgat gggcatgaat agtttgttgg tgtttttctt gtcggtcatt tctggactcg
     1801 tacaacttgt cgttattagt aaagttaaca ttgtacattt ctaccatttc tgcatggcta
     1861 ggaaaatcta agtaattact catgccaaaa tcagatacta attttagatt atctgtttta
     1921 tctagattga ggatatattt aatcaaacgc ctacgatatt tttttccgtg cgtcgcaaag
     1981 tgtttagtaa ctaccatgaa actccttcag tcttttcacc tccacttgaa attctttgtc
     2041 cacttcctta attaactctc cgactccttt actcaattct tgtaattggt cctgagaaat
     2101 cagatggctt tgattaatcg cacgcgcaat ttgattgatg ttatttccaa tacgtctcaa
     2161 ttcaaaaact aactggtcat aagtatcagt gttaatcgtg acaaatgaca tattgggatt
     2221 aagcaaaact tttctggcat agactgaaaa attttgacaa ttgctcttag caatccgttc
     2281 attcaattgg tgtaattctg gatcagttag aaatactttt ttgagattgg tacgatagcg
     2341 ataaaccatt acatcctcct aacccatata tttttcacga aactcacgac tgagtggctg
     2401 tacttgattg acttccgcaa tcaattcttg aacgcaagtc aataagattg agacgtgctc
     2461 ttgagtcact tgatgatttt ctcttgcgac aaccagaact tcatacacat ctcgactaat
     2521 ctgttcaaac ttttgagact gccaaaggga gaaccaactt tcaaaaattc tatcctgata
     2581 attctttttc aataaatttt gacgaagaaa ttctgagaaa ctatccactt tttgttccct
     2641 catcatttct tttatctgtt tttcttcttg tctcgtgctt ctaaattgct tacggattaa
     2701 cttaatttct tgtcccatct taccatcctt tcaacattat acttgtctga caatgtaagg
     2761 ctgcctcaca ttgtcagtac gattcctaaa gacctcagtc tctccttgtt cggtctttgc
     2821 gagctcagat attgtggaca caatatccca aaaatcatat cgccagccta tcaaaacctt
     2881 ctagttttga cagctaacca taagataact tggtggctcc gcccccaaac acccaggtaa
     2941 aattcttagt tggattttta aaagttgaga aaagtatagc agaagaaatt tggggaagtt
     3001 atcacaaatc aagtagggac taatctctaa cactactgca tgtatcgtcc tatatttatg
     3061 atcagctccc atcatttaca ttttcaggtc actgtctttt cataccagga attagaattg
     3121 acaaatttaa ttagagaggt attcatttaa ttgttcactt cttcgctcca tttccattac
     3181 agaaatttct tcaatactat gtgttcagct gactcccatg attcgttgta ctacgtccta
     3241 aacgctcacg gaataagccg tacatctttc ctagtttact ctcgtaattc acgtatatag
     3301 gttacgacac ctatttggat tttagagttc ctcatccgct atatatggct tcaagtcacg
     3361 attctgtttg tagagccttg atttcgctaa ttccttccta tcccccctac ctcacgatat
     3421 tcaggattag gagtcgctat tggtttcatc tgcagcaaat atccacagag gacttggacc
     3481 tcagatgtac actatgcctg tcggacaaag aaaaaagtag gctaaatttc tagcctactt
     3541 tttctgactc tactctgata aagccgtctc atatatagac attttatgct tgaaggaatc
     3601 ttttcctccc tctaattgat tgatgatatg attttttata tatttttcac taacatatcc
     3661 ctgtgattca atccatccgt taactccatc tgactccata ataacaactt gatctgtcat
     3721 agaatttgtt acaattgtag cattatgtgt tgctaaaata atttgacgtt gagctttcac
     3781 atctctaaac tgctgaacta aatgcctgta aatataacga ttgtctagat tgtcttcagg
     3841 ctgatcaata atcaatggtc tgaagtcttt agaatagtca ctatatgcta ataaaaaatc
     3901 aagcatggct acaacttttt gtcccaaact taatacacca acttctttat agagaatatc
     3961 aagttgttgc gaagattctt tcgagttaat attaaactcc aaaaatcgtg tattttcttt
     4021 agaaaaaatt tttcgtttat atgcacctaa taagtgagaa ccttttttca aaatgtcata
     4081 actattgaaa tgagcaatat agttaactat tttttgatta ttgaaatcct tcattatagt
     4141 cagtgaatgt tgataacttc catctttctc acttataata ttttcactta accattgatt
     4201 aacccatgat tcttgttcat aatcatatat acatacaata tgcaatttat ctgctgcact
     4261 aatttctact ccatgtaaaa tatgaggatg tatatcataa atcggataat ttttcattat
     4321 gattgagact gccatttgta actttttaat acctttggta gtattatgat cagttactac
     4381 aactatttct attccatttt ttatgattgc ctctgctaac ataagaaaac taatatattc
     4441 ttttgaacta gaaaaaacaa ccttatcaaa attactaaaa aaaattgtct tatcaacttt
     4501 t
//
LOCUS       DAVKBC010000076         4433 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVKBC010000076 DAVKBC010000000
VERSION     DAVKBC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.076"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(212..628)
                     /locus_tag="VWX64_001946"
     CDS             complement(212..628)
                     /locus_tag="VWX64_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9191354.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEQTERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(640..1096)
                     /locus_tag="VWX64_001947"
                     /pseudo
     CDS             complement(640..1096)
                     /locus_tag="VWX64_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(1196..1408)
                     /locus_tag="VWX64_001948"
     CDS             complement(1196..1408)
                     /locus_tag="VWX64_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU9191355.1"
                     /translation="MIGESMEGYTPGELTSIELLEGRYARIEALSVEKHAEDLLAVYG
                     PDTPQEMWTYLFQEPVADMEELVSLL"
     gene            complement(1626..4127)
                     /locus_tag="VWX64_001949"
     CDS             complement(1626..4127)
                     /locus_tag="VWX64_001949"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU9191356.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
BASE COUNT         1238 a         1012 c          835 g         1348 t
ORIGIN      
        1 agcttaactt ttctaaaatt ttactatttt gcaaaaaatt tctatcacca gcacctcacc
       61 acgcaaaaaa gccacctgat tgggtggctt cattaggaga ttgtgatgaa aaaagtttag
      121 gattttatta aataaagtta ggaggtcttt atttaatgac tatataatac tagaccatcc
      181 ttaaattttg cttaagaaaa aacaagtttt gttatttttt acgattcatc caagtcatcc
      241 ctatacaatt ataggtggat aagatttcaa agcccataga acgatagaag cccaaggttc
      301 tttctgtctg ttctgtcacc agctggactt gataggcatc tttgtaatcc tctaaagcct
      361 ctttcatcaa ggcactacca attccttgac gctgatagat tggtaaaacg attaaatcct
      421 gaaccaatac tgatgagaat ccatctccaa ccaaacgaat caagcccacc acagcatcac
      481 catcaagtgc cagataaatt actaatgaat gagataaggc ctgctccagc atctctggtt
      541 gatgggtata atttgtccaa ccgacagcct gatagagatg taaaacatcc tctagcttga
      601 caatttcttg ctttttaata gtaatcatct caacacctct taaagttctc tcaagctctt
      661 gtactgctgt ccatttttat caaaattttc aggacgcaac catgtttcca aacgatcttt
      721 gactttgggc cagtccttat caatcataga caaccaatcc atatctctcg tacgcccctt
      781 ataaaccact gcctgacgga aggttccttc ataaataaag cccaaacgct ccgcagcacg
      841 tctggatggc aggttaagag catcgcattt ccactcataa cgacgatagt taagctcttc
      901 aaagacatag cgagccagta gatactgggc ttctgtccct atccgtgtcc ccctgagttt
      961 tggagaaaaa gtgacagctc ccacttctat tactccgtta ctggtcaata cgcatgagag
     1021 aaaaagttcc caaagcctta ccagttgcct tgtctatgta gtaaaaacgg tccttacgag
     1081 ccaacatctg atttatagta aattgaaact aaaatagtac acttatactt ctaaaacatt
     1141 gttagaaatc gatttgactg tcctgatcga tttgtcctgt tcttatttca ttttactata
     1201 aaaggctgac cagctcctcc atgtctgcta ctggctcctg aaagaggtag gtccacatct
     1261 cctgaggcgt atcaggccca taaacagcta gcaaatcctc cgcatgcttt tccactgaaa
     1321 gagcctctat cctagcataa cgcccttcta agagttcaat agaagtcagc tcacctggtg
     1381 tataaccttc cattgactcc ccaatcattt gaccatattc atttactggc atagctttct
     1441 ccttttttca cttttcaaac tttatagttg cccatagtat accatacttt cataagaaga
     1501 ttcaaaaaat cctccagatt ctactctgaa ggattcctac cttatttcac aacgatatta
     1561 acgagtttag ttggctcaaa cagtttggga aactgtttga ggttggaaat cagcaaataa
     1621 attggttatt ttacaacaat attaaccaat ttatttggta cactaattac tttcacgatt
     1681 tccttaccgt caatttctgc tttgactttt tcatcagcta aagcgatttc ttgtaattct
     1741 tcacgtgata tatctttagc aaccatgagt ttggcacgga ctttaccttt gatttggaca
     1801 acgatttcga tttcgtcttc aaccagttta ctttcgtccc aagttggcca agctacataa
     1861 gagattgact cacctgtttc tgcgactgtt tgccagagtt cttctgccaa gtgaggtgca
     1921 aatggtgcaa tcaattgaat aaagcctttg gcatagtcaa cataaagctt atcttccttg
     1981 ttagcagcat tgacaaagac cataagttgg gcaatagctg tgttgaattt gagagactca
     2041 atttgctcag taacagcttt gactgtttcg ttgtaagcct tgtcaagagc accattgttt
     2101 tccgcaagga tttctttact tgtaatcaaa cggtaaactc ggtcaaggaa cttacggctt
     2161 ccttccaaac cttcttctga ccaagcaatc gaagcatcga gtggtcccat aaacatttca
     2221 taaacacgaa gggtatcggc accgtattgt tccaccacat catctgggtt aacaacgttc
     2281 ttgagcgatt tagacatctt ggctggcgct tgctccaact cttcccctgt ttctatatga
     2341 aagaaggaac catcacgttt ttcaaccttg tcggttgcca caagagcacc acggtggtca
     2401 cggtagcttg ttcccaaaat catcccttgg ttaaagagtt tttggaatgg ttccttagtc
     2461 ggaacaacac cgaggtcata gaggaattta tgccagaaac gagcataaag caagtgaagt
     2521 acagcatgtt ccgcaccacc cacgtagata tctactggca accattgttt gaggaggtcc
     2581 tcatcagcca atttctcagt attgtgcggg tcaatatagc ggaggtagta ccagcttgaa
     2641 ccagcccatt gtggcatggt gttagtttca cgacgacctt tgacaccatc ttcacgagtc
     2701 acttcaagcc aatctgtcaa gttagctagt ggactttcac cagtacctga aggacggata
     2761 tccttggtta caggcaagac aagcggcaat tcagtttcag gaacagctgt tgaagttcca
     2821 tcttcccaat gaatgattgg aattggctca ccccagtaac gttgacggct aaagagccag
     2881 tcgcggaggc ggtaggtaac cttctcctga ccacagcctt tttcttccaa gcaagccaca
     2941 atcttggcaa tagcgtcttc tttgttcaat ccatctagga agtctgaatt gacatgcagg
     3001 ccatcctctg tgtaggcagc ttcttcgaca tttccacctt caagtacttc gacgattgga
     3061 aggtcaaatt gtttggcaaa ttcccagtca cgttggtcgt gggcaggcac agccataacc
     3121 gcacctgttc cataactagc aagaacatag tccgcaatcc agattggcat ttccttacca
     3181 ttgacagggt tgatggcata ggcacctgtc caaacaccag ttttttcttt agcaaggtct
     3241 gtacgagcca agtcagactt aaggctggct tggtgtttat agtctgctac agcttctgct
     3301 tgctctgaac ttgtgatagc gtctactaat tcatgttcag gagccaagac agtgaaagtc
     3361 gcaccgaaaa gtgtgtccgg acgagtagta aagactgtaa attccttgtc tgttcctttt
     3421 actttgaaag ttacattggc accagttgat ttaccaatcc agttgcgttg catatccttg
     3481 atagactctg accaatctag ttcatctaag tcattgagca agcgctctgc gtaagccgta
     3541 attttgagca tccattggcg cattggtttg cggacaactg gatagcctcc acgctcagaa
     3601 gttccgtcag gaagcacttc ttcattggca atggcagttc ccaattcctc aacccagttt
     3661 actggcactt cagcttcata ggccaagcct ttttcgtaaa gcttggtgaa aatccattga
     3721 gtccacttgt agtagtttgg atctgttgtg ttgacttcac gatcccagtc ataagaaaat
     3781 ccaagcgcat tgatttgacg tttgaagttg gcaatgtttt ccgctgtaaa ttctgctggg
     3841 tcattaccag tatccatagc gtattgctct gcaggcaaac caaaagcatc ccaacccatt
     3901 gggtgaagaa cattgtagcc ttgcgcacgt ttgtaacgac tgaggatatc ggttgcagta
     3961 taaccttctg ggtgtcctac gtgcagacca gctccagacg gataagggaa catatcaagc
     4021 gcataaaact taggttttga tgcatctgtt cctgtcttaa atgtatgatg ttctgcccag
     4081 tagccctgcc acttaggctc aatttcttta tgattgtaaa aactcatggt ctctctccaa
     4141 ttttgtgatg ttactattat accatttttg agggaatttg aaatgtgttt aaaggaaaaa
     4201 ctgtatactg tatctcatta attttgatga ctatgaattg ctctatctcc cactttttat
     4261 cccattgtta tgcagtaaat caaggagtaa gtcaagaagc ttatctcgta tagcacaaaa
     4321 tacttatttt agaccgaaga taaaactgga atgctaatta atgtattcac aataaatagc
     4381 cgactaccta tgtcgctttt tgatttatga agaacgtata gtagactgaa tct
//
LOCUS       DAVKBC010000077         4418 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVKBC010000077 DAVKBC010000000
VERSION     DAVKBC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.077"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            245..1648
                     /locus_tag="VWX64_001950"
     CDS             245..1648
                     /locus_tag="VWX64_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEU9191357.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQKLESALKQYNGP
                     YILSDKRWDEVPIYLRYGVFRPSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYLYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAASGFRSWRETFPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            1832..2452
                     /locus_tag="VWX64_001951"
     CDS             1832..2452
                     /locus_tag="VWX64_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9191358.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYEELEKIDILNYQCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDN
                     DNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            2467..3207
                     /locus_tag="VWX64_001952"
     CDS             2467..3207
                     /locus_tag="VWX64_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191359.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            3210..>4418
                     /locus_tag="VWX64_001953"
     CDS             3210..>4418
                     /locus_tag="VWX64_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191360.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQMSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKVQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELRVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMN"
BASE COUNT         1543 a          554 c          823 g         1498 t
ORIGIN      
        1 tcgttccaat atgtgcacgt tggaatgtta gtgcttatat ggggggaatc caaaggattc
       61 tcccttttta ttttaataag tctgtctagc tatagatata ttaagtttga tagaatttct
      121 tggagatttt gttatggatt ataatttcaa tttggagcat cctttctttt tcactaataa
      181 tgattatagt acagatacta gcataaagta ctaagtaagt ctgcctttta attggcacga
      241 agtaatgaat aatgatgagt gggtttatca ataccctatt ggaaaatttg ttgaaagaca
      301 agggtggaaa atacacatta gttcagagta taatagttca cacgaattgt tacaagatgt
      361 agcaaaaatt tgccatgaaa tgcgaattcc atttaaacat cttagtacag aagacaaatt
      421 tatcatgcga aacgggaaat tggttagtcg aggattttct ggtaaattta ttacatgtta
      481 tccaaatcaa aatgaattag agtcggtttt gcaaaagtta gaaagtgcct taaagcaata
      541 taatgggcca tatattttaa gcgataaacg ttgggatgaa gtaccaatat atctgaggta
      601 tggtgtgttt aggccgtcaa gggatgatga aaagaaggtt gctattgatg aattaattgt
      661 tggcgatgaa gttgttaaag atgaacgttt accagtattt aaaattccaa aaggtatagt
      721 gccccctgac tttttgaata aatggcttga caagaaagat aaaaaacagg gagactttcc
      781 ctttattata gataatgcaa ttagattttc aaacagtggt gggatatata atgctagact
      841 aaaagaagat gggaaaaaaa taattttaaa agaggctaga ccgtatacag gtctaggatt
      901 tgatggtact tattcttcag agagattagc ttcggagtgc aaagcactaa aaattctaaa
      961 tgaatggagc gagatgccta aaatatactt gtacggtaag atctgggagc acaccttctt
     1021 aggaattgaa catatgaagg gcgttccact aaatagatgg gttaccaata attttccttt
     1081 atatgaagtt gttgataaga ccaaagatta tctattgaga gtttcaaaga tagtagaaaa
     1141 actcatcgat ttaacgaata agtttcattc tgaaaatgta tatcatcaag atttacattt
     1201 aggaaatatc ttggttaagg atgaagatga gattagtata atagactggg aacaggctgt
     1261 cttttcgaat gatgaaaaag ttgtacataa agttgcagcc tctggtttta gatcatggcg
     1321 agaaacattt cccagtgaga tagattggta tggtattaga caaatagctc attatttata
     1381 catgccacta gtaactacat cagatttgac atacaactat gtaagtcaaa ccaggataga
     1441 aggaaaaaaa ctatttgagt ctttgggtta tacaagagaa catatagatt atgtagaaag
     1501 tttattgtca tatctagatt ctaaatgtcc acagattgag aatatttcca ggaaaaaagt
     1561 tttaaaaccc atgcatgaga ttagaactat cgagagtgag caagatatac aagattttat
     1621 tataaaagcc tttcttttag tgaactgata ggtattttct tagcaaacga taaagtttta
     1681 gggccgatac aatcaattgc ctattcatta aataagataa atacaaccat taaggaaacc
     1741 gtttttaaaa tacttaagtg gagagaagaa ttttatagac gctgaacatg ataataacgg
     1801 actgtatact tcatcaatag atgagataca catgaaagat gttgtatatt ctattacacc
     1861 agaaaataaa ttaagtattg acttctcatt taagtcacca tttagggtat tattaacagg
     1921 aacttctggt agtgggaaaa caacgatttt aaatttaatt aatggttctt taaagccaca
     1981 aaaaggttat gtaaatttgt tatcacatgg gaaaaagagt tcagattcaa taccaacagt
     2041 tgatcagaca ccatatattt ttgacactac tattcgtgag aacgtaactt tatttcaaaa
     2101 tgaatatttt tcagatgatc agataattga ggtgttaaaa aaggtaaatc tatatgaaga
     2161 attagaaaag atagatatac taaattatca atgtggtgaa aatggtagta atttgtctgg
     2221 aggtcaaaaa caaaaaatag ctttagctag agctctgatt agaaataata aagtgtactt
     2281 atttgacgaa atatcagcta atttagataa tgataattca aattccatac atgatattct
     2341 gttcaattta ggtatttcat ttattgaagt ttcacatcat tatgacttaa atgacaagag
     2401 atacactgat atatataaat tggaaaatgg aacacttttc aaaattaagt gattggaggc
     2461 aagaatatgg ataaagatta tatattaaaa gtgaaagggc tgtatcatca atttttacta
     2521 ggaaataata aaacgttgca agtgctgaaa aatgtttctc tttctgcttc gagaggagaa
     2581 tttataagta ttctaggaat tagtggttct ggaaagtcaa ctttattaaa atgtatttct
     2641 agtttgcttg aaccaacaag tggggaagta attttaaatg gaatcaaccc ctataaaatc
     2701 agaaatgcaa aattgtcaag tataagacgt aacgaagtat cttttatatt tcaagcatac
     2761 aatttaatac cttccctgcc ggtaatagaa aatatagcac ttcctttgcg attatcacaa
     2821 aaaaaattaa ctattaaaaa tgtagaaaac ttactcaaaa gaatgaagtt taatgctggc
     2881 ttaaacgatt ttgttggaac tctgtctggt ggagaacaac agaaggttgc tatagctaga
     2941 gcggttattg ctgatagtga tataatattt gctgatgagc caactggggc tttagacagc
     3001 gtttctcgtg aagtaatttt tgaattattg agagagttag taggggcggg taagtgtgta
     3061 attatggtaa cgcacgatat agaattggcc tcgaaaactg atcgtgcatt aatattgaaa
     3121 gatggaaaaa ttttcaaaga acttcataga cctagcgggg aagagttgta taaaatctta
     3181 gaggtacaat caactacgga ggaatagaga tgctcagatt agtttactat caatttttac
     3241 ataataagaa acaatggtta ggcgtttcac cagtaatttt tgtttcgagt ttagttatgg
     3301 gattggctgt taatggggta attaatgttg agaataattc gcaagtattt gtcggacttc
     3361 cagatcctaa accaattttt atgtttccga tagtattcgg aggagtaaca ttattctttg
     3421 tgctctctaa cataataaat atgttggttg aaatttttag agatgattac gaacttctgg
     3481 aggtgttggg agcaagtcgc cttcaactat catttcttgt ggggggacag atttttatca
     3541 tttcctcgat tattagtttt attgcatatc tatgctctat atttgttacg tcaaattatt
     3601 attatttttt acaatacttt ttcggggaaa atatattacc tgatatccaa tttcaaatga
     3661 gtgctgttgg atgtatcatt acagtagtgt tgatttcatt tttagccttt ctaagtggtt
     3721 gcttttatac gttcaagaag attagaaata ggaagagttc taaaataagg catgttcttt
     3781 caatagtaaa aagaatactg ctattggctg gttttagtgt tatctggttg ctttctttgc
     3841 aacaaatttt ccaagatagc acaattttag cgaaggtcca gataatattc aatattgtaa
     3901 tcttagatat tgtgattatt tatcaattat ctccttttat acagtcatgt tttatcaaac
     3961 tactttctat aattatattt agaaataatt ttatgttcat tgtttcgaag tggaatttac
     4021 tatatcgtaa gccttatata aaatctatca gtgctgcaat tacaggagct atattactaa
     4081 tttctagttt tcaaatgatt tctcagaata tactatctca atttcaagat gacagtgatt
     4141 tagagctaag agtggcattt attgtctatg taggagcacc aattttgata gtacttgcaa
     4201 atattatttc aattgcattt ttgtcatcgc atcaagaaag gattgagatt cagcaatttg
     4261 aaattttagg aacttctaat taccagatgg ttaagattaa agttggtgag gctatatttt
     4321 tgacatttgt tacttcatta attgcatttt tacttaacat taaaattatg gctttaatat
     4381 actactcttt agaggatatt ttaatagatg atatgaat
//
LOCUS       DAVKBC010000078         4345 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVKBC010000078 DAVKBC010000000
VERSION     DAVKBC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4345
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.078"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..175
                     /locus_tag="VWX64_001954"
                     /pseudo
     CDS             1..175
                     /locus_tag="VWX64_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            342..542
                     /locus_tag="VWX64_001955"
     CDS             342..542
                     /locus_tag="VWX64_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191361.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            567..983
                     /locus_tag="VWX64_001956"
     CDS             567..983
                     /locus_tag="VWX64_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191362.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1214..1921
                     /gene="ccdA2"
                     /locus_tag="VWX64_001957"
     CDS             1214..1921
                     /gene="ccdA2"
                     /locus_tag="VWX64_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9191363.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1932..2489
                     /gene="sdbB"
                     /locus_tag="VWX64_001958"
     CDS             1932..2489
                     /gene="sdbB"
                     /locus_tag="VWX64_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU9191364.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2862..4253
                     /locus_tag="VWX64_001959"
     CDS             2862..4253
                     /locus_tag="VWX64_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU9191365.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLILLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
BASE COUNT         1274 a          784 c          917 g         1370 t
ORIGIN      
        1 aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa
       61 tggtgaatta atcgctccaa tgacttacga agagacgatg acgagcgact tttttgaagc
      121 ttggtttcag aagtttctct taccaacatt aaccacacca tcggttatta tagtaaaatg
      181 aaataagaac aggacaaatc gatcaggaca gtaaaatcga attctaacaa tgttttagaa
      241 gtctatatgt actattctag tttcaatatg ccataactgc tcctagtcaa cctgcaagtc
      301 ctgtcccagc tccaagctca gctccgattc aagatcctag agtggtagca agcgcttcgg
      361 ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga
      421 gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatcca aaaatcgatg
      481 caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt
      541 aaggtctgca tactgcagta gagtctgtga aggctgcctt ggactctctc aaagatgtga
      601 aagcaaatgc tagcgacagc aagcctgcac aggacaagaa ggatgcaaaa caaggaacgg
      661 aagatagtaa ggattcagat aagatgactg aaacaaactc agttccggca ggagtgattg
      721 tggtcagtct acttgccctc ctaggcgtga ttgccttctg gctgattcgc cgtaagaaag
      781 agtcagaaat ccagcaatta agcacggaat tgatcaaggt tctaggacag ctagatgcag
      841 aaaaagcgga taaaaaagtc cttgccaaag cccaaaacct tctccaagaa acccttgatt
      901 tcgtgaaaga agaaaatggc tcagcagaga cagaaactaa actagtagag gagcttaaag
      961 caatccttga caaactcaag taaaacatga tttatgaaat gtcagaccta aaagacattt
     1021 tcgttcacaa aagcagtgac gagtaatcct tgtcgttgct ttttggctat tttgggggat
     1081 aagatccgcc ttgactagca aaagaaaaga ttggtccaat agtgcccgat acgattttgc
     1141 gtagcagaaa gcttacaaat aaaattgaat atagtaaaat aggattagaa ttattaagaa
     1201 agttggttct ttattggaaa cgatagtatt tttaatctct gtttttctag caggtgtttt
     1261 atcctttttt tctccttgta tttttcctct tctgccagtc tatgctggga ttttattgga
     1321 tgatcaagaa agtgcaaaaa gcttttcttt gtttgggaga aaggttctct ggtcaggctt
     1381 gattcgaaca ctttgcttta tcgctggtat ctctctcatt ttctttattc taggctttgg
     1441 tgctggttac tttggtcata ttctctatgc aaattggttt cgatatgtca tgggagctat
     1501 tattatcatt ttgggtcttc accagatgga aatttttcat ttgaagaaat tagaagttca
     1561 aaaaagtttt acctttaaaa aatcagattc taatcgttat tggtcagctt ttttacttgg
     1621 tattaccttt agctttggtt ggacaccttg tattggtcca gttttaagtt ctgttttagc
     1681 acttgcggct tctggaggca atggcgcttg gcaaggagcg atttatactc tcatttacac
     1741 tctgggcatg gcccttcctt tcttggtatt ggcactagct tcaggtctag tcatgccata
     1801 ttttagtaaa atcaagcgtc atatgatgct actaaagaaa attggtggtt tcctcattgt
     1861 tttaatggga attttgttac tattaggaca agtaaatgtt ctagctggaa tttttgaata
     1921 aaggaggaca aatgaaaaaa gtaatgtttg ctggcttaag tctcttgtca ttagttgtat
     1981 tgatggcctg tggtgaggaa gaaactaaaa agactcaagc agcacaacag ccaaaacaac
     2041 aaacgactgt acaacaaatt gctgttggaa aagatgctcc agacttcaca ttgcaatcca
     2101 tggatggcaa agaagttaag ttatctgatt ttaagggtaa aaaggtttac ttgaagtttt
     2161 gggcttcatg gtgtggtcca tgcaagaaaa gtatgccaga gttgatggaa ctagcggcga
     2221 aaccagatcg tgatttcgaa attcttactg tcattgcacc aggaattcaa ggtgaaaaaa
     2281 ctgttgagca attcccacaa tggttccagg aacaaggata taaggatatc ccagttcttt
     2341 atgataccaa agcaaccacc ttccaagctt atcaaattcg aagcattcct acagaatatt
     2401 taattgatag ccaaggaaag attggaaaga ttcaatttgg tgctatcagt aatgcggatg
     2461 cagaagcagc atttaaagaa atgaactaga atcgataaaa tctgattaca agatgtagtc
     2521 agattttggt aacttctaaa actaacttcc agtttcccac aacctagctt ttagtatgag
     2581 aaaaacgcgt gacatcagtg gaaatccgtc ttagactaac ttccactggt tttctttttc
     2641 ttgatatata agggttcaaa agcgaaaaga ctcagaaaaa gtgcacgaca aatagcccta
     2701 aaacagagtc gtcttagagt aacttccagt tttgggagag agatggaagt tactttgaga
     2761 agttacggta gtcagatttt ttagaaaaac attttataaa tattcacata tctcctatat
     2821 ttatggtaaa atagaattat cagtttattt tggagttaaa gatgaatata tttagaacaa
     2881 agaatgttag tttagataaa acagagatgc ataggcattt gaagttatgg gatttgattt
     2941 tgctgggtat cggagccatg gtagggacag gcgtctttac aatcacaggt actgcagctg
     3001 caacacttgc tggcccagcc ctagtgattt caatcgttat ttctgccttg tgtgtgggat
     3061 tatcagccct cttttttgca gaatttgcct cgcgagtacc cgctacagga ggtgcctata
     3121 gttacctcta tgctatctta ggagaattcc ctgcctggtt ggctggttgg ttaaccatga
     3181 tggagttcat gacagccata tcaggcgtag cttcgggttg ggcagcttat tttaaaggct
     3241 tgctctctca atacgggata gcctttcctc aggctttaaa tggtaccttt aatcctcaag
     3301 cagggacatt tgttgattta ttgcctattc ttgtcttggt cttggtgact tcgcttgttt
     3361 tactaaatgc caaggcagcc ttacgcttta attcgattct agttattttg aaattttccg
     3421 ctttagctct ctttgtttta gtaggaattt ggaatattaa gtttgataat tggagcaatt
     3481 ttgctcctta cggttttgga caaatctatg gagctagcac tggtattatg gctggtgcgt
     3541 ccttgatgtt cttcggtttt ttgggatttg aatccatctc tatggctgta gatgaagtca
     3601 agactcctca aaaaaatatt cctagaggga ttgtcttatc gctttctatc gtaaccattc
     3661 tctatgcctt ggtgaccctt gttttgactg gtgtggttca ctatagtcat ttaaatgtcg
     3721 atgatgccgt tgcctttgcc cttcgtagtg ttgggattag ttgggcagcc aactatgtgt
     3781 cattagtggc tatcttgacc ttgattacag tttgtatttc gatgacctat gccctatcgc
     3841 gtatgattta cagtttagca cgtgacggct tagtgcctgc tgcctttaag gaactgacga
     3901 agactagcaa gataccaaag aatgctacta tcttgacagg tctagcttca gcagtagcag
     3961 caggaatgtt cccactagcc agtattgcag cctttttaaa tatttgtacc ttagcctact
     4021 tgatcctgct ggcttatggt ctgattcgct tacggaaaga aaaaggaatg cccaaagctg
     4081 gggaatttaa aacaccattg gtacctctgt taccaatttt atcgatcatc atttgtttat
     4141 ccttcatgtt acagtataat atgaatacct ggattgcttt cctagttgcg ttgttagtag
     4201 gaagtattat ttacttcact tatggctata agcattctac catagaagaa taaagtgaaa
     4261 gtctattgag ttgttgacac tcagcagatt tttatatgtg aaagaaattt caaatttttt
     4321 ctaaaaatat cttgacagat taaat
//
LOCUS       DAVKBC010000079         3749 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVKBC010000079 DAVKBC010000000
VERSION     DAVKBC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.079"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..624
                     /locus_tag="VWX64_001960"
                     /pseudo
     CDS             1..624
                     /locus_tag="VWX64_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(982..1515)
                     /locus_tag="VWX64_001961"
     CDS             complement(982..1515)
                     /locus_tag="VWX64_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU9191366.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1604..2380)
                     /gene="recX"
                     /locus_tag="VWX64_001962"
     CDS             complement(1604..2380)
                     /gene="recX"
                     /locus_tag="VWX64_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU9191367.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKLISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKKISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2418..>3749
                     /gene="rlmD"
                     /locus_tag="VWX64_001963"
     CDS             2418..>3749
                     /gene="rlmD"
                     /locus_tag="VWX64_001963"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9191368.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAV"
BASE COUNT         1238 a          609 c          666 g         1236 t
ORIGIN      
        1 taatttatct ccaaattttt atagtttgaa tattaaagga ttggaggtaa taaaaaataa
       61 gcaacaaaaa ctttttgaga agagtgggaa aaaactcata aaataaatac aattatggtt
      121 cagggattat gaaatcagct agattgtaat catgtagtta gtagagatga tctaaattta
      181 gtatatgact atttattcca gaaggaacga tgggagtcct atgagataac gctgattggt
      241 aatttatatc atctttttga aatagattat atttacatgg tcggaaaaga aatactagag
      301 cgtacacatt attacgaaaa aatcggcaag aatagaaatt tagttgtgtc agcttgttta
      361 aatttttggt tctgttgcct tgaaaattca catctaatat atgcagacta ctttgaaatg
      421 aaattaaaaa aattattaaa ggatgacaca aaagtttttg aaaaatctac attcaaattt
      481 gtagaaggat ataaaatata cctgacagaa tctaaagaat ctggaattaa acaaatggac
      541 aatgtcataa aatattttga gtttattgaa tctaaaagta ttgctttata ttttcaaaaa
      601 cgattaaatg agctgataga ttaaatagca ttttctctgt tgagatattg tttttaaaat
      661 attgtactaa atgattgatg ctatgtggaa atacaaaaaa atgtttttga tacgaagttg
      721 acctgtattt tttatactaa tcattttcgt attttttgta ttaaacgata taagtttgtt
      781 gtaaacttac aaggaataaa gacattaaaa aataacagta tatctatttg ttttatatat
      841 tttacgaatt ctgcataaat ttctttctag taatgtgttg taactctgct ataatggatt
      901 tattcctttt tgtgtttaca caatttattt tatactacca aaaaaacaag gtcaggattt
      961 tgttcctgac ctttgacaac tttaccgatt ctttagttct acatagcgct tgtaccaaat
     1021 gtttacatag gcttctgaga aaggaccacg tccattgtta atccaatcaa caagaatttt
     1081 gacatgttct tttaaaatat agtccaagtc atcagaataa ttcattttgc gtttgtgacg
     1141 ctcgtactct tcaacgtcca agagacgttt ttccccatct gtaaaaattt taacatccaa
     1201 atcgtaatca atatacttca gtgcttcttc atccagatag taggggctag ccatattgca
     1261 atagtaagaa gttccattat cacgaatcat ggcaatgata ttaaaccaat atttcttgtg
     1321 aaagtaaaca atagccggtt ctcgagtgac ccaacgacga ccatcacttt cggtaacaag
     1381 tgtatgatcg ttgacaccaa taatggcgtt ttctgttgtt tttagtacca tggtgtcccg
     1441 ccaagttcgg tggagactcc catcatgctt ataactttga attgtaataa agtcgccttc
     1501 ttttggaagc ttcataacta accaactttc tacaatttat aagtttatca tttactattg
     1561 taccataaaa ttacctaaaa tctgtgaatt tcacttggaa atattaaaga tattctctaa
     1621 gagcgcttgc tatatccgaa aaatcgtagc cctttcgtgc taaaacttga gttaaacgct
     1681 gcttcagttc gtatccttca tactttcgag catacttagt atattgctta tcaagttcct
     1741 tgaagatgag ttcttgagtc gtttcttggt caacttggct atctaagtcg tcaaaggcaa
     1801 ttttagcatc agaataagag aagcccttgt tagtcaagtt ctggataatc ttatcttgca
     1861 gggcacgagc tggaagtttt ccctcatatt ttttcaatag tttattagct acacgttgag
     1921 caacttcaga aaaatcaaat tctttcaagt tctcttctat agtagatttt gaaatctttt
     1981 tttgagctag tttctgagtc agcacataag gacccttgtc tcctgaaagt tgattggtat
     2041 tgatgatagc ataagcgtac tgaccatcat taatccactt atcttcttta agattagcaa
     2101 taacttgaga aacgatgttt ttatcaatat cgtatttttt cagatattct ctgacttctt
     2161 tttcagtgcg tgctttaaag gataagtggt agagggccag attcttacca taagaaaatt
     2221 gagcaaagtc ttgaatctct ttcaattcct cttcgcttat cagcttatct ctcgataaca
     2281 taaaacgaac aattgtatct tcggtgatat agcatttgtc gccattatca agctccatca
     2341 gatagagtct ttttttcttt tcaagttttg tgattttcat agctctatta taactcaaaa
     2401 tgtgataaga taggggtatg aatctgaaag tgaaacaaaa aataccatta aaaatcaagc
     2461 gcatgggaat taacggtgag ggaatcggct tttaccaaaa aacattagtc tttgtaccag
     2521 gagctctcaa aggcgaagat atctattgtc agattacttc tattagacgc aactttgttg
     2581 aagcaaaatt actgaaggtc aacaagaagt ctaaatttcg aattgtgcca tcttgtacta
     2641 tttataatga atgcggaggc tgccaaatca tgcacctgca ttatgataag cagctggagt
     2701 tcaagacgga cttacttcat caagcgctga aaaaatttgc tcctgcagga tatgaaaatt
     2761 atgaaattcg tccaactatt ggaatgcagg aaccaaaata ttacagagct aagttacaat
     2821 ttcagactcg aaaatttaaa aatcaggtca aggcgggctt atatgcacaa aactctcact
     2881 atttagtaga gttgaaagac tgcctggtac aagataagga aacccaagtg attgctaatc
     2941 gcttagcaga attacttact tatcaccaga ttccaatcac ggatgagaga aaagttctag
     3001 gtgtccgtac tattatggtc cgacgcgcga gaaagaccgg acaggttcag attattattg
     3061 ttacaaaccg ccagcttaat ttaactcaat tggtaaaaga gttggttaaa gatttcccag
     3121 aagttgtgac agtagctgtt aatacaaata cagctaaaac cagtgagata tatggtgaaa
     3181 agacagagat tatctggggg caagagagta ttcaagaagg tgtactcaat tatgaatttt
     3241 cactatcccc tcgagctttt tatcaactaa atcctgagca aacagaagtc ctctatagcg
     3301 aagcagtaaa agcgctggat gttgataaag aagaccattt gattgacgct tattgtggag
     3361 ttggaacgat tggatttgcc tttgcaaaga aagtaaaaac actcagaggt atggatatta
     3421 ttccagaagc tattgaagat gccaagcgaa atgctaaaag aatgggattt gacaatactc
     3481 attatgaagc tggaacggca gaagagatta ttcctcgttg gtacaaggaa ggctaccgag
     3541 cagatgcttt gattgttgac ccaccacgta caggtctgga tgataagtta ttagatacta
     3601 ttcttactta tgtaccagaa aaaatggttt atatttcttg taatgtttcg accttggctc
     3661 gtgatttggt acgcttagta gaagtctatg atcttcatta tatccagtcg gtcgatatgt
     3721 tcccacatac agctcgaact gaagctgtt
//
LOCUS       DAVKBC010000080         3446 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVKBC010000080 DAVKBC010000000
VERSION     DAVKBC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3446
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.080"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            29..1378
                     /locus_tag="VWX64_001964"
     CDS             29..1378
                     /locus_tag="VWX64_001964"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU9191369.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDKKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            1502..2962
                     /locus_tag="VWX64_001965"
     CDS             1502..2962
                     /locus_tag="VWX64_001965"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU9191370.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            2976..3410
                     /locus_tag="VWX64_001966"
     CDS             2976..3410
                     /locus_tag="VWX64_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9191371.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGKERASKFNER"
BASE COUNT         1136 a          670 c          727 g          913 t
ORIGIN      
        1 agaaaagaag aaatattgga ggaagaacat gtcacatatt aaatttgatt attcaaaagt
       61 tttagacaaa tttgttgcac cacatgaagt ggaatacatg caatcacaag taacagcagc
      121 agatgaattg atccgtaaag gaactggtgc tggtagcgac ttcttgggat ggttggacct
      181 tcctgaaaaa tacgatcgcg aagaatttga ccgcatcttg aaagctgctg agcaaatcaa
      241 gtcagacagc gatgttttgg ttgtgatcgg tattggtgga tcttaccttg gtgcaaaagc
      301 agcaatcgac ttcttgaatc accattttgc taacttgcaa acaaaagaag aacgcaaagc
      361 tccacaaatc ctttacgcag gaaactcaat ctcatctact taccttgctg acttggtaga
      421 gtatgttgca gacaaagact tctcagtaaa cgtaatttct aaatcaggta caacaactga
      481 accagcgatt gctttccgtg tctttaaaga actcttggtt aagaaatacg gtcaagaaga
      541 agctaacaaa cgtatctatg caacaactga ccgccaaaag ggtgctgtta aggttgaagc
      601 agacgctaac ggttgggaaa catttgttgt tccagatgat atcggtggac gcttctcagt
      661 attgacagcc gttggtttgc ttccaatcgc agcatcagga gctgacatca aagctcttat
      721 ggaaggtgcg aatgcagctc gcaaagacta cacttcagac aaaatctctg aaaacgaagc
      781 ttaccaatac gcagctgttc gtaacatcct ttatcgtaaa ggctatgcaa ctgagatctt
      841 ggtaaactat gagccatcac ttcaatactt ctcagaatgg tggaaacaat tggctggtga
      901 atcagaagga aaagacaaaa aaggtatcta cccaacttca gccaacttct caactgactt
      961 gcactcactt ggtcaattta tccaagaagg aactcgtatc atgtttgaaa cagttgtccg
     1021 tgttgacaaa cctcgtaaaa acgtgcttat tcctactttg gaagaagacc ttgacggact
     1081 tggttacctt caaggaaaag acgttgactt tgtaaacaaa aaagcaactg acggtgttct
     1141 tcttgcccac acagatggtg atgtaccaaa catgtatgtg actcttccag agcaagacgc
     1201 tttcactctt ggttacacta tctacttctt cgaattggca attgcccttt caggttactt
     1261 gaatgctatc aacccatttg accaaccagg tgttgaagct tataaacgta acatgtttgc
     1321 ccttcttgga aaaccaggat ttgaagaatt gagcaaagaa cttaacgcac gtctataata
     1381 gaagaaaaga gtggtttgcc cactcttttt actctcttta tccatagaaa ttggactcag
     1441 ccaagacttg tgatataata tagaaagcaa aaaggcagac gcctagataa taggagaaac
     1501 tatgtcaaaa gatatccgcg tacgttacgc accaagtcca acaggactac tacacatcgg
     1561 aaatgcccgt acagcattgt ttaactactt gtatgcgcgc catcatggtg gaacatttct
     1621 catccgtatc gaagatactg accgtaaacg ccatgtcgag gatggtgaac gttcacaact
     1681 tgaaaacctt cgctggttag gcatggattg ggatgaaagt ccagaatcac atgagaatta
     1741 tcgccagtct gagcgtttgg acttgtatca aaaatacatt gaccaactat tagctgaagg
     1801 aaaagcctat aaatcttacg ttacagaaga agagttggca gctgaacgtg aacgtcaaga
     1861 agctgctggt gaaacacctc gatatatcaa cgaatacctt ggtatgagtg aagaggaaaa
     1921 agcggcttat atcgcagaac gtgaagcagc tggtatcata ccaacagttc gtttggctgt
     1981 caatgagtca ggtatctaca agtggcatga tatggtcaaa ggtgatatcg aatttgaagg
     2041 tggcaatatc ggcggtgact gggttatcca aaagaaagac ggttacccaa cttacaactt
     2101 tgccgttgtt atcgatgacc acgatatgca aatctctcat gttatccgtg gagatgacca
     2161 tattgctaat acaccaaaac agcttatggt ctatgaagct cttggttggg aagctccaga
     2221 gtttggtcac atgaccttga ttatcaactc tgagactggt aagaagttat ctaaacgtga
     2281 tactaataca cttcaattta tcgaagatta ccgaaagaaa ggttaccttc cagaagcagt
     2341 ctttaacttt attgctcttc ttggttggaa cccaggtggt gaagatgaga ttttctctcg
     2401 tgaagaactc attaaacttt ttgatgaaaa ccgcctcagc aagtcaccag cagcctttga
     2461 tcagaaaaaa ctagactgga tgagcaatga ttatatcaag aatgcagacc ttgaaaccat
     2521 ctttgaaatg gcaaaaccat tcttagagga agcaggccgt ttgactgaca aggctgaaaa
     2581 attagttgag ctctataaac cacaaatgaa atcagtagat gagattatcc cattgacaga
     2641 tcttttcttc tcagatttcc cagaattgac agaagcagag cgcgaagtca tgacgggtga
     2701 aacagttcca acagttcttg aagcattcaa agcaaaactt gaagcgatga cagatgatga
     2761 atttgtgaca gaaaatatct tcccgcaaat taaagcagtc caaaaagaaa caggtattaa
     2821 agggaaaaat cttttcatgc ctattcgtat cgcagtttca ggcgaaatgc atgggccaga
     2881 attaccagat acaattttct tgcttggacg tgaaaaatca attcagcata tcgaaaacat
     2941 tctaaaagaa atctctaaat aaagaggata caataatgga catctgggaa aagatgtacg
     3001 aagaagcaca gaaactatac aatccacatg aagtatcaga ctttgtttat gccaatcatg
     3061 ttgtagctgc agtagaagca ggagatggac aaatatttac aggattctgt atggagggaa
     3121 cctgtggtgt tttccatctc tgcgcagaac gggcggccct cttcaatatg taccaatttt
     3181 caggacaaac taaggttaag aaagtattag cctttcgaga caaaccacct tatggtggaa
     3241 gttcagccat gccttgcggt gcttgtagag aattcctttt agagcttaat gctgaaaata
     3301 aagatgcaga attcatgatg gactataata taagaaaaac agttaaagtc gcagaactaa
     3361 tcccttattg gtggggaaaa gaacgtgctt ctaagtttaa tgagcgatag aagagtcagt
     3421 ataattctgg ctctttttac tataag
//
LOCUS       DAVKBC010000081         3281 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVKBC010000081 DAVKBC010000000
VERSION     DAVKBC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.081"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            40..3159
                     /gene="phtE"
                     /locus_tag="VWX64_001967"
     CDS             40..3159
                     /gene="phtE"
                     /locus_tag="VWX64_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU9191372.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKIDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEEVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQQSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1219 a          540 c          636 g          886 t
ORIGIN      
        1 ttgagaaaaa acttcatcat ttattgaaat gagggattta tgaaatttag taaaaaatat
       61 atagcagctg gatcagctgt tatcgtatcc ttgagtctat gtgcctatgc actaaatcag
      121 catcgttcgc aggaaaataa ggacaataat cgtgtctctt atgtggatgg cagccagtca
      181 agtcagaaaa gtgaaaactt gacaccagac caggttagcc agaaagaagg aattcaggct
      241 gagcaaattg taatcaaaat tacagatcag ggctatgtaa cgtcacacgg tgaccactat
      301 cattactata atgggaaagt tccttatgat gccctcttta gtgaagaact cttgatgaag
      361 gatccaaact atcaacttaa agacgctgat attgtcaatg aagtcaaggg tggttatatc
      421 atcaagatcg atggaaaata ttatgtctac ctgaaagatg cagctcatgc tgataatgtt
      481 cgaactaaag atgaaatcaa tcgtcaaaaa caagaacatg tcaaagataa tgaggaggtt
      541 aactctaatg ttgctgtagc aaggtctcag ggacgatata cgacaaatga tggttatgtc
      601 tttaatccag ctgatattat cgaagatacg ggtaatgctt atatcgttcc tcatggaggt
      661 cactatcact acattcccaa aagcgattta tctgctagtg aattagcagc agctaaagca
      721 catctggctg gaaaaaatat gcaacagagt cagttaagct attcttcaac agctagtgac
      781 aataacacgc aatctgtagc aaaaggatca actagcaagc cagcaaataa atctgaaaat
      841 ctccagagtc ttttgaagga actctatgat tcacctagcg cccaacgtta cagtgaatca
      901 gatggcctgg tctttgaccc tgctaagatt atcagtcgta caccaaatgg agttgcgatt
      961 ccgcatggcg accattacca ctttattcct tacagcaagc tttctgcctt agaagaaaag
     1021 attgccagaa tggtgcctat cagtggaact ggttctacag tttctacaaa tgcaaaacct
     1081 aatgaagtag tgtctagtct aggcagtctt tcaagcaatc cttcttcttt aacgacaagt
     1141 aaggagctct cttcagcatc tgatggttat atttttaatc caaaagatat cgttgaagaa
     1201 acggctacag cttatattgt aagacatggt gatcatttcc attacattcc aaaatcaaat
     1261 caaattgggc aaccgactct tccaaacaat agtctagcaa caccttctcc atctcttcca
     1321 atcaatccag gaacttcaca tgagaaacat gaagaagatg gatacggatt tgatgctaat
     1381 cgtattatcg ctgaagatga atcaggtttt gtcatgagtc acggagacca caatcattat
     1441 ttcttcaaga aggacttgac agaagagcaa attaaggctg cgcaaaaaca tttagaggaa
     1501 gttaaaacta gtcataatgg attagattct ttgtcatctc atgaacagga ttatccaagt
     1561 aatgccaaag aaatgaaaga tttagataaa aaaatcgaag aaaaaattgc tggcattatg
     1621 aaacaatatg gtgtcaaacg tgaaagtatt gtcgtgaata aagaaaaaaa tgcgattatt
     1681 tatccgcatg gagatcacca tcatgcagat ccgattgatg aacataaacc ggttggaatt
     1741 ggtcattctc acagtaacta tgaactgttt aaacccgaag aaggagttgc taaaaaagaa
     1801 gggaataaag tttatactgg agaagaatta acgaatgttg ttaatttgtt aaaaaatagt
     1861 acgtttaata atcaaaactt tactctagcc aatggtcaaa aacgcgtttc ttttagtttt
     1921 ccgcctgaat tggagaaaaa attaggtatc aatatgctag taaaattaat aacaccagat
     1981 ggaaaagtat tggagaaagt atctggtaaa gtatttggag aaggagtagg gaatattgca
     2041 aactttgaat tagatcaacc ttatttacca ggacaaacat ttaagtatac tatcgcttca
     2101 aaagattatc cagaagtaag ttatgatggt acatttacag ttccaacctc tttagcttac
     2161 aaaatggcca gtcaaacgat tttctatcct ttccatgcag gggatactta tttaagagtg
     2221 aaccctcaat ttgcagtgcc taaaggaact gatgctttag tcagagtgtt tgatgaattt
     2281 catggaaatg cttatttaga aaataactat aaagttggtg aaattaaatt accgattccg
     2341 aaattaaacc aaggaacaac cagaacggcc ggaaataaaa ttcctgtaac cttcatggca
     2401 aatgcttatt tggacaatca atcgacttat attgtggaag tacctatctt ggaaaaagaa
     2461 aatcaaactg ataaaccaag tattctacca caatttaaaa ggaataaagc acaagaaaac
     2521 tcaaaacttg atgaaaaggt agaagaacca aagactagtg agaaggtaga aaaagaaaaa
     2581 ctttctgaaa ctgggaatag tactagtaat tcaacgttag aagaagttcc tacagtggat
     2641 cctgtacaag aaaaagtagc aaaatttgct gaaagttatg ggatgaagct agaaaatgtc
     2701 ttgtttaata tggacggaac aattgaatta tatttaccat cgggagaagt cattaaaaag
     2761 aatatggcag attttacagg agaagcacct caaggaaatg gtgaaaataa accatctgaa
     2821 aatggaaaag tatctactgg aacagttgag aaccaaccaa cagaaaataa accagcagat
     2881 tctttaccag aggcaccaaa cgaaaaacct gtaaaaccag aaaactcaac ggataatgga
     2941 atgttgaatc cagaagggaa tgtggggagt gaccctatgt tagatccagc attagaggaa
     3001 gctccagcag tagatcctgt acaagaaaaa ttagaaaaat ttacagctag ttacggatta
     3061 ggtttagata gtgttatatt caatatggat ggaacgattg aattaagatt gccaagtgga
     3121 gaagtgataa aaaagaattt atctgatctc atagcgtaag gaatagcagt agaaaaagtc
     3181 tgaatcaaaa atgaagttct ctcaaaagtt agaaataaaa ctctgacttt gggagaattt
     3241 cattttatta ttaatatata aaatttcttg acatacaact t
//
LOCUS       DAVKBC010000082         3249 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVKBC010000082 DAVKBC010000000
VERSION     DAVKBC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3249
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.082"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            15..905
                     /locus_tag="VWX64_001968"
     CDS             15..905
                     /locus_tag="VWX64_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="HEU9191373.1"
                     /translation="MWRIKLFIDILKKKKMKIIEAHDALSAYIIDQTKYSADKGDIFE
                     YDGIWISSLCDSIIRGKPDMEVVNITDRLQTIDDILCVTEKHIIVDIDSGGTLAQTAS
                     LIEKITLRKIAGIVIEDKIGQKYNSLFGEKNTQLQDSTESFERKIRVAIKSRKNSKTA
                     IIARIESLVLGKSLEDLLYRGNCYIKSGAEALVIHALNSRLDDLYQALKYFKRYFPEI
                     PLIVIPTDFPYVCAEELFESGADLIIYANHLLRSIIKPMEYIAKSILIDGYSNGVENK
                     LLPISEILNYIPLLEEIDEK"
     gene            895..1992
                     /locus_tag="VWX64_001969"
     CDS             895..1992
                     /locus_tag="VWX64_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191374.1"
                     /translation="MKSKDLISSLKLNGVTRFFGVPDTFLYPITSQLANDELIIVPNE
                     GNAVSMAFGYSITTSRMPVIFLQNSGLGNILDPVQSLVGQAVYNHPMLYIIGFRGGTD
                     DAPQHSECGKVTKKLLEISQFDIYEKDYFTNALDTDIRRIIDNIKKKNKSAAILVDKE
                     FFSDIVNIKNYQISDYNDILNKICAVLEKEKDSIVLTSTGYITRHMENVKDTYKKNFV
                     HIPMPGSLGQTISFGAGICMGTSINNKKKKIYIIDGDGSLFMHMGSLALFDYYNLDVT
                     YILLNNYKHLSVGGENTLASSCNFFKLAESMNFDNIYSSDNLEVVDFEEKLNQQGKNF
                     IEIICSNEVTYSLLERMDFNFEEIKQFNMEN"
     gene            1994..2785
                     /locus_tag="VWX64_001970"
     CDS             1994..2785
                     /locus_tag="VWX64_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191375.1"
                     /translation="MPDRYVEYSQNDYDNIMKLDTLFISQLDSKYKVEYHKLPSLISG
                     EVLKRCGYFSTMPNQLSKVDIIDVSQLESLGNNRELEEIKYSSSENYFLTPAACLHFY
                     PMLEHKEVKECIYSSLVDVFRYENGNFTMGTRQWEFTVREFLAIGNPKFVEEFLEDLK
                     EKFLTIALRFDSTAKIQNACDNFYPTNLNKVKQKFQKYNNLKFELIVHISEKEVSVAS
                     FNYHNNHFSKEFNFDSNDTIVTGCVGLGIDRWISLIKESEKDYKL"
     gene            2785..>3249
                     /locus_tag="VWX64_001971"
     CDS             2785..>3249
                     /locus_tag="VWX64_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU9191376.1"
                     /translation="MRKQIISLFHAYLNENTQDWVEIDENFLLYQHLDMFYYYLCKKN
                     NIEPPLMEKFEVRKKVIESRNRQYIKVARDLNAIFEKQSIQVAFLKGIQTSEKYYEEP
                     WIRYYSDLDILVAREMIPGVEKLFYQLGYVFGHLKDNGEIHHATREEILYQKL"
BASE COUNT         1228 a          368 c          577 g         1076 t
ORIGIN      
        1 ttagaattgt attaatgtgg agaataaaat tgtttattga tattttaaaa aagaaaaaaa
       61 tgaaaattat tgaggcacat gatgcactaa gtgcctatat tatagaccag actaaatatt
      121 ctgctgataa aggtgatatc tttgaatatg atggaatttg gattagttcg ctctgtgatt
      181 caataattcg agggaagcca gatatggaag tcgtaaatat aaccgatcga cttcaaacaa
      241 ttgatgatat tttatgtgtt actgaaaaac atattatagt agatattgac agtggaggta
      301 cattagcaca aacagcttct ttgatagaaa aaatcacact gagaaaaatt gcaggaatag
      361 taatagaaga taagatcggc caaaagtata attctttatt tggtgagaaa aacactcaat
      421 tacaggatag tacagagtct tttgaaagaa aaataagggt tgcaattaaa tcgagaaaaa
      481 atagtaaaac agcaattatt gctcgaattg agagtctagt tcttggaaaa agtttagaag
      541 atttactata tagaggaaac tgttatataa agtctggtgc tgaagcattg gtaattcatg
      601 cattgaattc cagattagat gatttatatc aagcgcttaa gtattttaag agatactttc
      661 cagaaatacc acttattgtt atcccaacag attttccata tgtttgtgca gaggaattat
      721 ttgagagcgg agcagactta attatctatg ctaaccattt gttaagaagc attatcaaac
      781 caatggaata tattgcaaaa agtatattga ttgatggtta tagtaatggg gtagaaaata
      841 agttattacc tataagtgaa atattgaatt atataccatt attggaggag atagatgaaa
      901 agtaaagatt taataagttc tttgaagtta aatggtgtaa ctcgtttttt tggggttcca
      961 gatactttct tgtatcctat tacttcacaa ttagcgaatg atgaattgat aattgtacca
     1021 aatgagggca atgcagtttc aatggctttt ggatatagta ttacaacaag taggatgcct
     1081 gtaatttttt tacaaaattc aggattagga aatatattag atcctgtaca aagtttagtg
     1141 gggcaagcag tttataatca tcctatgctc tatataattg gatttcgggg aggaacagat
     1201 gatgctcctc agcattctga gtgtggtaag gtaacaaaga agcttttgga gataagtcaa
     1261 tttgatatat atgaaaaaga ttattttaca aacgcccttg atactgatat aagaagaatt
     1321 attgataata tcaaaaaaaa gaataaaagt gcagccattc tagtggataa agaatttttt
     1381 tcagatattg ttaatataaa aaattaccaa atttctgatt ataacgatat acttaataaa
     1441 atatgtgctg ttctggaaaa agagaaagac tctattgttc tcacatcaac aggatatata
     1501 actcgtcata tggagaatgt aaaagatact tataaaaaga actttgttca tatacctatg
     1561 ccaggctcat taggacaaac aatatctttc ggtgctggta tatgtatggg aacttctata
     1621 aataataaaa aaaagaaaat atatattatc gatggagatg gttccttatt tatgcatatg
     1681 ggttctttag cgttatttga ttattataat ttagatgtta catatatctt gttaaacaac
     1741 tataaacatc tatcagttgg gggagaaaac acattagctt cgagctgtaa tttttttaag
     1801 ttagctgaat ctatgaattt tgataatata tattctagtg ataatttaga agtggttgat
     1861 tttgaggaaa aattaaatca gcaaggaaag aattttattg aaataatttg ttctaatgaa
     1921 gtgacttatt cattattaga aagaatggat tttaatttcg aagaaataaa acaatttaat
     1981 atggagaatt aatatgcctg atagatacgt tgaatatagt caaaatgact atgataatat
     2041 catgaaatta gatactttat ttatatcaca gttagatagt aaatataaag ttgagtacca
     2101 taagttaccc tctttaatca gtggcgaagt tttaaagcgt tgtggatatt tttctacaat
     2161 gccaaatcag ctatctaaag tagatataat tgatgtttct caactagaat ctctgggaaa
     2221 taacagagaa ttagaagaaa ttaaatatag ttcatcagaa aattattttt tgacaccggc
     2281 agcctgctta catttttatc ctatgttaga acataaagag gttaaagaat gtatttatag
     2341 ttctttagtt gatgtgttcc gttatgaaaa tggtaatttt acaatgggta ctcgtcaatg
     2401 ggagtttacg gtaagagaat ttcttgctat tggaaatccg aaatttgtgg aagaattctt
     2461 agaagattta aaagaaaaat tcttaactat agcacttcga tttgattcaa ctgccaaaat
     2521 ccaaaatgct tgtgacaatt tttatccgac gaatctaaac aaagttaagc aaaaatttca
     2581 aaagtataat aacctaaagt ttgaactaat tgtccatatt tcagaaaagg aggtatctgt
     2641 agcttcgttc aattatcata acaatcattt cagtaaagaa tttaattttg atagtaatga
     2701 tacaattgta acaggatgcg ttggattagg gattgataga tggataagtt taataaaaga
     2761 gtcagaaaag gattataagt tataatgaga aaacaaatca tatcgctgtt tcatgcttat
     2821 cttaatgaaa atacccaaga ttgggtggaa attgatgaaa atttcttact ttaccaacat
     2881 ttagatatgt tttattatta tttatgtaaa aagaataata tagaacctcc tttaatggaa
     2941 aaatttgaag ttagaaaaaa agtaatcgaa agcagaaatc gtcagtatat aaaagttgca
     3001 agagacttga atgctatatt tgaaaaacaa tctatacaag ttgctttttt aaaaggaatt
     3061 caaacctctg aaaagtatta tgaagaacca tggattagat attatagtga tttagatatt
     3121 ttggtagcta gagaaatgat accaggggta gaaaaattat tttaccaact gggttatgtt
     3181 tttgggcatc tcaaagacaa tggtgaaatt catcatgcaa ctcgagaaga aatactctat
     3241 caaaaactc
//
LOCUS       DAVKBC010000083         3222 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVKBC010000083 DAVKBC010000000
VERSION     DAVKBC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3222
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.083"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..1385
                     /locus_tag="VWX64_001972"
     rRNA            <1..1385
                     /locus_tag="VWX64_001972"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1437..1509
                     /locus_tag="VWX64_001973"
     tRNA            1437..1509
                     /locus_tag="VWX64_001973"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1470..1472,aa:Ala,seq:tgc)
     gene            1634..>3222
                     /locus_tag="VWX64_001974"
     rRNA            1634..>3222
                     /locus_tag="VWX64_001974"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          904 a          649 c          960 g          709 t
ORIGIN      
        1 atagctaata ccgcataaga gtagatgttg catgacattt gcttaaaagg tgcacttgca
       61 tcactaccag atggacctgc gttgtattag ctagttggtg gggtaacggc tcaccaaggc
      121 gacgatacat agccgacctg agagggtgat cggccacact gggactgaga cacggcccag
      181 actcctacgg gaggcagcag tagggaatct tcggcaatgg acggaagtct gaccgagcaa
      241 cgccgcgtga gtgaagaagg ttttcggatc gtaaagctct gttgtaagag aagaacgagt
      301 gtgagagtgg aaagttcaca ctgtgacggt atcttaccag aaagggacgg ctaactacgt
      361 gccagcagcc gcggtaatac gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc
      421 gagcgcaggc ggttagataa gtctgaagtt aaaggctgtg gcttaaccat agtaggcttt
      481 ggaaactgtt taacttgagt gcaagagggg agagtggaat tccatgtgta gcggtgaaat
      541 gcgtagatat atggaggaac accggtggcg aaagcggctc tctggcttgt aactgacgct
      601 gaggctcgaa agcgtgggga gcaaacagga ttagataccc tggtagtcca cgctgtaaac
      661 gatgagtgct aggtgttaga ccctttccgg ggtttagtgc cgtagctaac gcattaagca
      721 ctccgcctgg ggagtacgac cgcaaggttg aaactcaaag gaattgacgg gggcccgcac
      781 aagcggtgga gcatgtggtt taattcgaag caacgcgaag aaccttacca ggtcttgaca
      841 tccctctgac cgctctagag atagagtttt ccttcgggac agaggtgaca ggtggtgcat
      901 ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct
      961 attgttagtt gccatcattt agttgggcac tctagcgaga ctgccggtaa taaaccggag
     1021 gaaggtgggg atgacgtcaa atcatcatgc cccttatgac ctgggctaca cacgtgctac
     1081 aatggctggt acaacgagtc gcaagccggt gacggcaagc taatctctta aagccagtct
     1141 cagttcggat tgtaggctgc aactcgccta catgaagtcg gaatcgctag taatcgcgga
     1201 tcagcacgcc gcggtgaata cgttcccggg ccttgtacac accgcccgtc acaccacgag
     1261 agtttgtaac acccgaagtc ggtgaggtaa ccgtaaggag ccagccgcct aaggtgggat
     1321 agatgattgg ggtgaagtcg taacaaggta gccgtatcgg aaggtgcggc tggatcacct
     1381 cctttctaag gataaggaac tgcgcattgg tcttgtttag tcttgagagg tcttgtgggg
     1441 ccttagctca gctgggagag cgcctgcttt gcacgcagga ggtcagcggt tcgatcccgc
     1501 taggctccat tggtgagaga tcaccaagta atgcacattg aaaattgaat atctatatca
     1561 aatagtaaca agaaaataaa ccgaaaacgc tgtagtatta ataagagttt atgactgaaa
     1621 ggtcagaaaa taaggttaag ttaataaggg cgcacggtgg atgccttggc actaggagcc
     1681 gacgaaggac gtgacaaacg acgatatgcc ttgggtagct gtaagtaagc gatgatccag
     1741 ggatttccga atgggggaac ccaacaggta atacctgtta cccacatctg ttaaggatgt
     1801 gaggaggaag acgcagtgaa ctgaaacatc taagtagctg caggaagaga aagcaaaagc
     1861 gattgcctta gtagcggcga gcgaaacggc agaagggcaa accgaagagt ttactcttcg
     1921 gggttgtagg actgcaatgt ggactcaaag attatagaag aatgatttgg gaagatcagc
     1981 caaagagagt aatagcctcg tatttaaaat agtctttgta cctagcagta tcctgagtac
     2041 ggcgggacac gtgaaatccc gtcggaatct gggaggacca tctcccaacc ctaaatactc
     2101 cctagtgacc gatagtgaac cagtaccgtg agggaaaggt gaaaagcacc ccgggagggg
     2161 agtgaaatag aacctgaaac cgtgtgccta caacaagttc gagcccgtta atgggtgaga
     2221 gcgtgccttt tgtagaatga accggcgagt tacgttatga tgcgaggtta agttgaagag
     2281 acggagccgt agggaaaccg agtctgaata gggcgcctta gtatcatgac gtagacccga
     2341 aaccatgtga cctacccatg agcaggttga aggtgcggta agacgcactg gaggaccgaa
     2401 ccagggcacg ttgaaaagtg cttggatgac ttgtgggtag cggagaaatt ccaaacgaac
     2461 ttggagatag ctggttctct ccgaaatagc tttagggcta gcgtcgacat tagagattct
     2521 tggaggtaga gcactgtttg ggtgaggggt ccatcccgga ttaccaatct cagataaact
     2581 ccgaatgcca atgaattatg gtcggcagtc agactgcgag tgctaagatc cgtagtcgaa
     2641 agggaaacag cccagaccac cagctaaggt cccaaaataa ttgttaagtg gaaaaggatg
     2701 tggggttgca cagacaacta ggatgttagc ttagaagcag ctattcattc aaagagtgcg
     2761 taatagctca ctagtcgagt gaccctgcgc cgaaaatgta ccggggctaa aacaatttac
     2821 cgaagctgtg gataccttta taggtatggt aggagagcgt tctatgtgtg atgaaggtat
     2881 accgtgagga gtgctggaac gcatagaagt gagaatgccg gtatgagtag cgaaagacag
     2941 gtgagaatcc tgtccaccgt aagactaagg tttccagggg aaggctcgtc cgccctgggt
     3001 tagtcgggac ctaaggagag accgaaaggt gtatccgatg gacaacaggt tgatattcct
     3061 gtactagagt atgtagtgat ggagggacgc agtaggctaa ctaaagcaga cgattggaag
     3121 agtctgtcta agcagtgagg tgtgaattga gtcaaatgct taattctata acattgagct
     3181 gtgatgggga gcgaagttta gtagcgaagt tagtgacgtc ac
//
LOCUS       DAVKBC010000084         3021 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVKBC010000084 DAVKBC010000000
VERSION     DAVKBC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3021
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.084"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            187..1164
                     /locus_tag="VWX64_001975"
     CDS             187..1164
                     /locus_tag="VWX64_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9191377.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETATTFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQTHHT
                     MTEEVAAFAHMIQQPDLNLYQTWLDDAGSVHELLYTMRQTAGIRFEAEK"
     gene            1161..2243
                     /locus_tag="VWX64_001976"
     CDS             1161..2243
                     /locus_tag="VWX64_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9191378.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFDPLLTGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKNGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2307..3021)
                     /locus_tag="VWX64_001977"
                     /pseudo
     CDS             complement(2307..3021)
                     /locus_tag="VWX64_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          938 a          668 c          534 g          881 t
ORIGIN      
        1 tatattatag cacattttta aatctaggtt tactagattc tctggctcta tctatttatt
       61 cggaaaagaa agcttttctt cagaagaaag ctagtagctt atttgaaatt ttctcctctc
      121 tgttggatag tcccgtctat ctatgttata atgaaagaag gatttaaaat cggaaaagga
      181 gtatttatgc taaaattagg tgtcatcgga actggcgcta tcagccatca tttcatagaa
      241 gcagcccata ccagtggaga ataccaactg gtcgcaatct attctagaaa actagaaact
      301 gcaacaacct ttgcttctcg ctatcagaat atccaactat tcgatcaatt agaagtcttc
      361 ttcaaatctt cttttgattt agtttatatc gccagtccaa actccttaca ttttgctcag
      421 gcaaaagctg ccttgtctgc tggtaaacat gttattcttg aaaagccagc tgtcactcaa
      481 ccacaagaat ggtttgattt gattcaaaca gctgaaaaaa ataactgttt tatctttgaa
      541 gcagctcgta attaccacga gaaagccttt actactatca aaaacttttt agcagataag
      601 caagtgttag gagcagattt caactatgcc aaatactctt ccaagatgcc tgacttgttg
      661 gctggacaaa caccaaatgt cttttcagac cgttttgctg gtggagccct catggatttg
      721 ggaatttatc ccctctatgc tgctgttcgt ctttttggaa aagctaatga cgcgacttac
      781 catgctcaac agcttgacaa tagcattgac ctaaatggag atggtatcct cttctaccca
      841 gactatcaag ttcacatcaa ggctggaaaa aacatcactt ccaatcttcc ttgcgagatt
      901 tatacaacag atggaacctt gactctcaac acgattgagc atattcgctc agctattttt
      961 accgaccacc aaggaaatca agtccagctt cctatccaac agactcatca tacgatgact
     1021 gaggaagtcg ctgcatttgc acacatgatc cagcaaccag atctgaatct ctaccaaact
     1081 tggctggatg atgcaggctc tgttcatgag ctactatata ccatgcgcca gactgctggc
     1141 attagatttg aggcagaaaa atgaaaacca aactaccgac tgaatggcaa gaactgagtg
     1201 accaactcgg tttccaagaa ttcaccccca ttcaaactca actatttgat ccccttctta
     1261 ctggagaaaa cctcctagga gtgagccaaa ccggaactgg taagacccta gcgtatctcc
     1321 taccaagtct tctcagacta caaaagaaaa aagcccaaca actcttgatt ctagcaccaa
     1381 acacggaact tgctggacag atttttgatg tatgtaaaac gtgggcagaa gctatcggat
     1441 tgactgctca actcttcctt tcaggttcaa gtcagaaacg acaaattgaa cgccttaaaa
     1501 acgggccaga aattctgatt ggaactcctg gccgtatctt tgaactcatt aaacttaaaa
     1561 aaatcaagat gatgaatgtg gaaaccatca tcctggatga atttgaccaa ttactagatg
     1621 attctcagat tcactttgta gaaaaaatca ctcactacgc acctcgtgac caccaactgg
     1681 tctacatgag tgccacgacc aagtttgacc aagaaaagat tgtgccgaat acacgcacta
     1741 ttgatctctc tgatcaaaaa ttggacaata tccagcattt ctacatgcag gtagaccaac
     1801 gtcatcgagt ggatatgcta cgaaaactgg ctcatgtaga ggatttccgt ggtctagtct
     1861 tcttcaatag cctgtcagac cttgggaatg ccgaggaaaa actacagtat cgtgatatat
     1921 tggctgtttc cctcgctagt gatgttaatg ttaaatttag aaaaatcatc ttagaaaagt
     1981 ttaaagataa ccaactaacc ctgcttcttg caactgacct tttggctcgt ggaattgata
     2041 tcgatagcct agaatgtgtc gtaaactttg atattcctag agatagcgaa acctacacac
     2101 accgtgctgg ccgtactggt cgtatgggca aggaaggtta tgttatcact ctcgtcactc
     2161 atccagaaga aatcaaaaaa cttaaaaagt ttgcaagtat ccgagaaatt gtcctaaaaa
     2221 accaagaact ctatatcaaa taaagcccca ttgctctata cacatccagt gtatggagct
     2281 tttttataag caattcaatt ttatactcat ctgctttcaa aaagcattct agtccatctc
     2341 cgattaacga tggactttat cacctccttc tccaatcctt gtatgacatc ttgaagttga
     2401 ttcatgacat cttccaaaat tcgaaaggct ttattcttaa atccacgttt acgaatctct
     2461 ttccacactt gttcaatggg gttcatctct ggtgtgtatg gaggaataaa tgcaaaacca
     2521 atattagtcg gaatctttaa gatacttgat ttatgccata tagcattgtc cataacgagt
     2581 aaaaaataat catctggata agcttgtgaa agctcttcta aaaaggcgtt catccactca
     2641 gtattacatc taccagctat taagaaaaat gattcgcctg tatgggcatc aacagctcca
     2701 taacaatagc gaaattctcg tatatagtga ctatggatat gtggacctac tcctattgga
     2761 gcccaacaag atcccagttt actgattcta ccgaaaccag cctcatcttg gtacatcaag
     2821 cgaaccttac gaaaacgtct actatattta aaacgctttc ttgccttctt gaattgagat
     2881 tttattttta gacgcgacaa tggtttgagc gtctgctttc ttaggatgtt ctggacgtgg
     2941 cataatattt cgccaaccat ggcgcttcaa cagttgatag aaggcatcac gtgtgtagga
     3001 acgacctaac tcctttttat a
//
LOCUS       DAVKBC010000085         2905 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVKBC010000085 DAVKBC010000000
VERSION     DAVKBC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2905
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.085"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            117..1034
                     /locus_tag="VWX64_001978"
     CDS             117..1034
                     /locus_tag="VWX64_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU9191379.1"
                     /translation="MRKTFIDELINKNIEEQNIVVLTGDVGRSTYASKFKEIFPENYL
                     NLGICEANIVGISAGIAGTLEFVPFVMLFSKHLILRALEQINDSILMNKKKVILVGGY
                     SGYSASKEGETHQLLNDISILSSFPDISIYCPYDQSSIQTAINESINNDYSSYIRINK
                     NKILNDVVSRYISQGNKSIIISMGYLGSLLSKKYMEDSDIREFADFILVSKIKPIDWE
                     YWENFLRKYETVYIIEENTLTGGLGEQFKNYFFGLGINIISFGIKPHFGETGDYETLL
                     TNEGLSPDKIFEKIRRINHVQSSEKSIWR"
     gene            1000..2208
                     /locus_tag="VWX64_001979"
     CDS             1000..2208
                     /locus_tag="VWX64_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HEU9191380.1"
                     /translation="MYNLVKRVFGDDNFVKSDGIYLYTDDNKEIIDSCSNSMNVNLGY
                     GVLEIEKVIHEQIRKINFMHTGKGTTYESLMLANRLHDIIKPYGNYKVYFATSGSDCI
                     EAALRISVLYQQKNKRNQESNTRFATFEGSYHGSTLGALSVSGHRKFQKLYNGYIGNC
                     LTIPTRWNLEWEMDFTDITAFVLDSMITNPIGSEMIDRDYLNYLVQICKESGVITIID
                     EIATSIGRLGCFFGFEDSGISPDIVCISKGLGVGYANIGAVIVKSNIIDSINSADILG
                     HTYNASPIDCKIAMTVLDYIEEHGIFEHVNNLSNYIEYRLKVLKNKLPCISKVSGKGF
                     MWSIHFRNNVNASKVFKQCYNNGLLLLYLEYEEYNHMTFCPPLITSKNQIDSMLDILE
                     KSITEVLHGY"
     gene            2198..>2905
                     /locus_tag="VWX64_001980"
     CDS             2198..>2905
                     /locus_tag="VWX64_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU9191381.1"
                     /translation="MDIKKLGFIIITNETFAFNLVEEVVEKLSILDVNRAIIKLLPKV
                     DETTLIKHYREHLINWNGKEGKSQVPSLGWPAVRNRFSSSVVLILLEGNKQSLSDEIL
                     QIKGNTYPERCRQNQIRIKGFNPTYNLMHSSDSAEEALKEAELYFSKKELESFFCGEI
                     GITFEEILNFILELDSIQKGGIRSNSDLENKVNKMCYWKQRIFDLFSSKTKEESRKIS
                     EELNFIKSNRSPEDVILY"
BASE COUNT         1078 a          340 c          538 g          949 t
ORIGIN      
        1 aagggaatag aatttatgga agggaagacg gaatttcatt catataacat tttatcgagt
       61 gaaaaggaag tattatacaa gagagcaatg gaatgtttag gtggagataa aatggcatga
      121 gaaaaacatt tattgacgag ttaataaata aaaatattga agaacagaat atagtagtat
      181 taacaggtga tgttggaaga tcaacgtatg ctagtaagtt taaagaaatt tttcctgaaa
      241 attatttaaa tttaggtatc tgtgaagcta atattgtagg aataagtgca ggaatagcag
      301 gaactttaga atttgttcca tttgtaatgc tatttagtaa acatttgatt ctaagagcgc
      361 ttgaacaaat caatgatagt atactaatga acaagaaaaa agtgatttta gtaggaggct
      421 attcaggtta ctcagcttca aaagaaggag aaacacacca gttattaaat gatatttcga
      481 tattaagttc atttccagac atatcaattt actgtccata tgatcagtcc tcgattcaaa
      541 ctgctattaa cgaaagcata aataatgatt attcctccta tattagaatt aataaaaata
      601 aaattttaaa tgatgtagtc agtcgctata tcagtcaagg aaataaaagc ataattatct
      661 caatgggcta tctcggatcg ctactctcaa aaaaatacat ggaagattca gatattaggg
      721 agtttgctga ttttatttta gtaagtaaga tcaaacctat tgattgggaa tattgggaaa
      781 attttttacg caaatatgaa accgtataca taattgaaga gaataccctt acaggtgggt
      841 taggagaaca atttaaaaat tatttttttg gattaggaat aaacatcatt tctttcggta
      901 ttaaacctca ctttggagaa actggtgatt atgaaacctt acttacaaac gaagggcttt
      961 cccctgataa aatttttgag aaaattagaa ggataaatca tgtacaatct agtgaaaaga
     1021 gtatttggag atgataattt cgttaagtca gatgggattt atctatacac tgatgataat
     1081 aaggagataa tagatagttg ttctaattca atgaatgtca atctgggtta tggtgtgtta
     1141 gagattgaaa aggtgattca tgaacaaata cggaaaatta attttatgca tacaggcaaa
     1201 ggaacaacct atgaatcatt gatgttagct aatagattgc atgacataat aaaaccttac
     1261 ggtaactata aagtgtattt tgcaacttct ggttcggatt gtattgaagc tgctctcaga
     1321 atatcagtgt tatatcaaca aaaaaataaa agaaatcaag aatccaatac tagatttgcc
     1381 acatttgaag gaagttatca cggttctaca cttggtgcgt taagtgtatc tggtcataga
     1441 aaatttcaaa aattatataa tggctatatt ggtaattgtt taactattcc tacgcgatgg
     1501 aacttggaat gggaaatgga ttttacagat attactgcgt ttgtattgga tagtatgatt
     1561 actaatccaa taggctctga gatgattgat agagactatc taaattattt ggtgcaaata
     1621 tgtaaagagt ctggcgttat aacaattatt gatgaaattg ctacatcaat tggacgactt
     1681 ggttgctttt ttggattcga ggatagtgga atttcgccag atatagtttg tatatctaaa
     1741 ggtttaggag ttgggtatgc gaatataggt gcagtaattg tcaaaagtaa cattattgat
     1801 tctattaatt ctgcagatat tcttggtcat acatataatg catcgccaat agattgtaaa
     1861 attgccatga ctgttttaga ttacatagag gaacatggta tatttgaaca tgtgaataac
     1921 ttatctaatt atatagaata tagattaaag gttctaaaaa ataaactacc atgcattagt
     1981 aaagttagtg gaaaaggctt tatgtggtct atccatttcc gcaataatgt aaatgctagt
     2041 aaagtattta aacaatgtta taataatggt cttttgcttc tttatttgga gtatgaagaa
     2101 tataatcata tgactttttg tcctccctta ataacaagta aaaatcaaat agactctatg
     2161 ttagacatat tagaaaaatc aattacggag gtactacatg gatattaaaa aattaggatt
     2221 tatcataatt acaaatgaaa cctttgcgtt taatttagta gaagaagttg tggaaaaatt
     2281 gtcaatactg gatgtaaatc gagccatcat aaaattgttg ccaaaagtag atgaaactac
     2341 tctaattaag cactatagag aacatctaat taattggaat ggaaaggaag gaaaatctca
     2401 agttccttct ttaggttggc cagctgttag gaatagattt tcttcatcag ttgttttaat
     2461 tttattggaa ggaaacaagc aaagtttatc tgatgaaata ctccaaataa aggggaacac
     2521 ttatcctgag cgatgccgac aaaatcaaat taggattaaa gggtttaatc caacatataa
     2581 tcttatgcat tcttcagaca gtgctgagga agctcttaag gaggcagaac tatatttttc
     2641 taagaaagaa cttgaaagtt tcttttgtgg agaaattggt attacttttg aagaaattct
     2701 aaactttatt ttagagcttg attcaattca aaaaggaggt atacgatcta atagtgattt
     2761 agagaataaa gtaaataaaa tgtgttattg gaaacaaaga atttttgatt tgtttagttc
     2821 taaaacgaaa gaagaaagta gaaaaatatc tgaagagctt aattttataa aatcaaatcg
     2881 ttcccctgaa gatgttattt tatat
//
LOCUS       DAVKBC010000086         2732 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVKBC010000086 DAVKBC010000000
VERSION     DAVKBC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.086"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..381)
                     /locus_tag="VWX64_001981"
     CDS             complement(<1..381)
                     /locus_tag="VWX64_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191382.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKY"
     gene            complement(395..1108)
                     /locus_tag="VWX64_001982"
     CDS             complement(395..1108)
                     /locus_tag="VWX64_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU9191383.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1567..1947)
                     /locus_tag="VWX64_001983"
     CDS             complement(1567..1947)
                     /locus_tag="VWX64_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU9191384.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(2369..>2732)
                     /locus_tag="VWX64_001984"
     CDS             complement(2369..>2732)
                     /locus_tag="VWX64_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU9191385.1"
                     /translation="RNKNGQADTNQTEKPQTEKPEEETPREEKPQSEKPESPKPTEEP
                     EESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDN
                     NTIMAEAEKLLALLKESK"
BASE COUNT          841 a          533 c          431 g          927 t
ORIGIN      
        1 atattttgct acatgatcta ggtatatatc aaaaaagtca tgaggaaaat ctcccataca
       61 gccattacga ttcatattga ggctatattt tcgattagta agataattcg gaaatatatt
      121 tcctattact ctaagattat ctacttgtga atcccttctc ccaatataat ccccttcttt
      181 gactaatgat ggagatttcc aagtaaaaat taaatcgcca gagaaatttt tcttatcaaa
      241 aaacttaaaa agagattgat aaatactatt tgctaattga caagtgtcag atgtaaattc
      301 ataattaaca gcttcattaa aatcaacttc agacatttca atgtactctt caatagtaat
      361 attagctttt tttgtagtca ttagctaatc tcctttaaaa cgtgatcttt tcaagaatat
      421 ttttatctaa acaatccagc aagtcttggt aagaatagac ttcgtaagtc ggctgggctt
      481 gtgtgtgatt ttcgaggtga tgaggattat accagatagt gtcaatcccc gcattattgc
      541 caccttgaat gtcggcggtt agagaatctc caatcatcag cgtcttttct ttactaaatc
      601 cagcaatttg ctggccaatc ttttcataaa aaagagcatc cggcttttga gtttgcaact
      661 gttctgagat aaagacttga ttgaaataag gtgctagacc agattgagcc aaacgtcctg
      721 tctgaatggc agtaatgcca tttgtcgcag catacaagtt ataatcacgc tcaatgaggc
      781 tgtccaagag atcatgagcg cccgatagtg tttgtccctg ctgggcgagg taaaattggt
      841 aacgctgggc aagaaaacta ccgtcttttt cctgtccaaa atgagcaaat aaacgagaaa
      901 agcgcgtgtt aaccagctct tgtttactga ttttcttcag ctccaagtct ttccagagag
      961 ccttgttcat aggaacgtaa taatctttat aagcctgaat atccgcaact ccttcttctt
     1021 ttagaagttg agtcaaagcc acatcctcag cagcatcaaa atcaagaaga gtgtggtcga
     1081 ggtcgaagag tagaaatttg tagaacaatt tgaggttttc ctttctgaaa attcattaag
     1141 aacattatat cataaagcac ctcatacaat taactaattt aatcacttaa aaaaaattcg
     1201 aacactttct atacaactga cagctcaaat ctttcagaat agaacaatac taactatcga
     1261 acaccctgtc ttcataaata catatgtaat tctaggccta gaattcctat aaactaaatg
     1321 ctttcatact cttccaagta attgattgcc ttaaatttta atttttgaag gtttctaaag
     1381 ctagaatagc cccatcacaa tcagttttga ttgattcaca atttagaaac actatagttt
     1441 cactcctgtt aaaataaaaa ggaactgcat aaagcaatcc ctttctgatt ttgaaatcat
     1501 ttacttaaca ttttatagtt gagataatca atagcttatc tataaaaaga gttatagtaa
     1561 aattccttat ttattgattt caagctccgc taactgtatt tgaataactg acagttctgc
     1621 accagcctga agaagagcag ctgcattata ggcaccttct acaattggaa ccctgttgat
     1681 gatgatactt ttatcactga aatcagtcac catttttaag ttcattttag cagaacctag
     1741 gtcaaaaaag gcaagtaaag tatctgctgg attttcggaa acaaccctat ctacttgatc
     1801 aaaactcgtt ccaattcctc cgccctcggt tcctcctaca taagtaatcg gaacatcttt
     1861 agctacttta ctaatcagtt caacaacacc ttctgcaatg tgtttggaat gtgaaacgat
     1921 aacaagacca ataccaatac tttccatcaa accactccag tttctaaaat agcagtaaag
     1981 agtaatcctg atgagaatga tccaggatca atatgtccaa gaaaccacat gctcctaaga
     2041 caagagctaa cagactggcc atcaataata gtattgttct ttttttcatc attactcctt
     2101 aactagtgtt taactgatta attagccagt aaatagttta tctttattta cactatctgt
     2161 taagatatag taaaatgaaa taagaacagg acagtcaaat cgatttctaa caatgtttta
     2221 gaagtagagg tatactattc tagtttcaat ctactatatt ttgcacattt tcatgaaaaa
     2281 aatgagaact agaactcaca ttctgctctc atttttcgtt ttcccgttct cctatcctgt
     2341 ttttaggagt tagaaaatgc tgctaccttt acttactctc ctttaataaa gccaatagtt
     2401 tttcagcttc tgccataata gtattgttgt cctgggtgcc aaatagtaaa ttatttttta
     2461 atcctgtgag agtctctttg gcattggact tgataattgg atcctggatt tttccaagta
     2521 aatcttcagc ctctctcagt ttttcttcaa ccttttcagt ctcgacctga ggttcttctg
     2581 attcctctgg tgattcttct ggttcctctg ttggttttgg agactctggt ttctcgcttt
     2641 gcggtttctc ttctcgaggg gtttcttcct caggtttttc tgtctgaggt ttctccgttt
     2701 gattggtatc agcttgacca tttttgtttc tt
//
LOCUS       DAVKBC010000087         2716 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVKBC010000087 DAVKBC010000000
VERSION     DAVKBC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.087"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            21..986
                     /locus_tag="VWX64_001985"
     CDS             21..986
                     /locus_tag="VWX64_001985"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU9191386.1"
                     /translation="MAIIKKIVVLYGGLSEEREVSENSAKEISKSLLTLGYDVISIDL
                     SQDCSYEIGEIEKSERGLNKQKVEIGSGIIDVCRKVDIVFLATHGGIGENGKLQAIFD
                     VEKIDYTGNSFLSTAISMDKKLSKIVASSVGIKCASNLMVDRIQANDFPIVIKPIRSG
                     SSKGIKIFQNKKQFDIYYKEHPELGSVFVEKYIKGREFSVGILGETVLPVIEIKVKNG
                     FYDYNNKYTVGAAEEVVPAKISEKLTHTLQKSAYKIHKALGFNVYSRTDFIVDEKGDV
                     YFIESNSLPGMTKTSLLPQEAKAAGIDFPNLCERIIELSREIRSQ"
     gene            1052..2260
                     /locus_tag="VWX64_001986"
     CDS             1052..2260
                     /locus_tag="VWX64_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enolase"
                     /protein_id="HEU9191387.1"
                     /translation="MKIINGICRYIFDSKGFATIEVEIFLDSGDTGIGAAPRGSTTGH
                     YDIQYNEYYPRGNNFSPIPDGNIEFFNENILPRIINREVEDIEDITELDKHLFDIPEI
                     ENYGNVAIACSYAVWEAFSKNKKSPLWKLFFEPGSASKGKVKHLVNIIDGKPDSLLAG
                     FEFLLVSEKEITFQSLLEISNIKNELMIKFKNQGFYTSISNQGALIINTDDFYIILDS
                     LLETLKLYKNRYDIGLDLAMTDRYDSSLGIYKVPWCVSQQQTVTEIMDTYCDWGVKYP
                     LVYLEDPFSDEDLDSWRKFQLIKPLKLQVFGDDFYATNLERISQFKDCADGIVIKPNQ
                     VGSVSKTLEVMEYAEKSGISMAFSQRTAETENNIISHLAMSVTSSYLKAGGLDRLDRI
                     AKYNEVLRNG"
     gene            2253..>2716
                     /locus_tag="VWX64_001987"
     CDS             2253..>2716
                     /locus_tag="VWX64_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HEU9191388.1"
                     /translation="MDNGKISTDGALVNNKNIEVNISSASIRYGISVFEAPKMFLLGS
                     DIYIFRFQDYFNRLKTSCKFLNIELPLDSNKLLYDIKKFIEFVPWQESYALRINVFCP
                     YESELLGEVECALTLSYLDIGIRSKSGVSSKVIKRSNLIRTSNNNLYMIKSPS"
BASE COUNT          980 a          319 c          530 g          887 t
ORIGIN      
        1 ctaataagga ggttaagtga atggctatta ttaaaaaaat tgttgtacta tatggtggcc
       61 ttagcgaaga gagggaggtg tcagaaaatt ctgcaaagga aattagtaaa agtctattaa
      121 cattggggta tgatgtgatt tctatagatt tatctcaaga ctgttcgtac gagataggag
      181 aaattgaaaa aagtgagcgc ggattaaata aacaaaaagt tgagattggt tcgggtatta
      241 ttgatgtttg tagaaaggtt gatatagttt tcttagcaac tcatggtgga ataggtgaga
      301 atgggaaact acaggctatt tttgatgtag aaaaaataga ctatacagga aattcgtttc
      361 ttagtacagc tattagcatg gataaaaaat tatcaaaaat agtggctagt tctgttggaa
      421 taaaatgtgc ttcgaacttg atggttgata gaattcaggc aaatgatttt cctattgtta
      481 taaagccaat tagaagtggt tcaagtaaag gtattaagat atttcaaaat aaaaaacaat
      541 ttgacattta ttataaagag catcctgaac ttggttcagt ctttgtagaa aagtatatta
      601 aggggagaga attttcggta ggtattttag gtgaaactgt tttaccggtt attgaaataa
      661 aagtaaaaaa tggtttttat gattataata acaagtacac tgttggtgca gctgaagaag
      721 tcgttcccgc aaaaatatct gaaaagttaa ctcatacctt acaaaaatcc gcatataaaa
      781 tacataaggc tcttggattt aatgtttatt cacgtactga ttttattgta gatgagaagg
      841 gggatgtata ttttattgaa tcaaatagtt taccaggtat gactaaaaca agtttattac
      901 cacaggaagc gaaagcagct ggtatagatt tcccaaacct atgtgaacgt attattgagc
      961 tgagtaggga aattagatct caatagaaaa taaaatcgac gacatttata aaaaaagtaa
     1021 ttttcaatga taaaaaagaa agtggaagcc tatgaaaata attaatggta tttgcagata
     1081 tatctttgac tcaaaagggt tcgcaacaat tgaagtagag atttttcttg atagtggaga
     1141 tactggaatt ggtgctgctc cacgagggtc tacaactggg cattatgata ttcaatataa
     1201 tgagtattat cctagaggaa acaactttag tccaatacca gatggaaata tagaattttt
     1261 caatgaaaac atccttcccc gaattattaa tagggaagtt gaagatattg aagatattac
     1321 agaattggat aagcacttat ttgatattcc tgaaatagaa aattatggta atgtagcaat
     1381 agcttgttcc tatgctgttt gggaagcgtt ttctaaaaat aagaaatcac ctttatggaa
     1441 attatttttt gaaccaggtt ctgcatcaaa aggaaaggtg aaacatttag tcaatataat
     1501 agatggaaag ccagatagct tacttgcagg ttttgaattt cttttagtat ctgaaaaaga
     1561 aattactttt caatcattat tagaaatatc taacataaaa aatgagttaa tgataaagtt
     1621 taaaaaccaa ggtttctaca catctatttc taatcaaggt gcattaataa ttaacacgga
     1681 tgatttttat attattttgg attcgttatt agagacatta aaattataca aaaatagata
     1741 tgatatcggt ttagatttag caatgacaga tcgttacgat tcttcacttg gcatatataa
     1801 agtaccatgg tgtgttagtc agcaacagac agtcacagaa attatggata cttattgtga
     1861 ttggggagtt aagtatccat tggtttatct tgaagatcca ttttccgatg aagatttgga
     1921 tagttggaga aaatttcaat tgataaaacc tctaaagtta caagtttttg gtgatgattt
     1981 ttacgcaaca aacttagaaa gaatttcaca gtttaaagat tgtgctgatg gtattgtaat
     2041 aaagcctaat caagttggct cagtgagtaa aacacttgag gtgatggaat atgcggaaaa
     2101 atcagggatt agtatggctt tttcacaacg cactgctgag actgagaaca atattatatc
     2161 acatttagca atgagtgtga cttcttctta tttaaaagct ggaggtctgg acaggttgga
     2221 tagaattgca aaatataatg aggtattaag aaatggataa tggaaaaatc agtacagatg
     2281 gggcacttgt taataacaaa aatatagagg ttaatataag ctcagcttcc attagatatg
     2341 gaattagtgt ctttgaagca cccaaaatgt tcttacttgg ttcagatatc tatattttcc
     2401 gatttcagga ttattttaat cgtttgaaaa ctagttgcaa gtttttaaat atagagttac
     2461 ctttagattc taataaactt ttatatgaca taaaaaaatt tattgaattc gtaccttggc
     2521 aggaatcgta tgctttgaga ataaatgttt tttgtcccta tgaaagtgaa ctgttaggtg
     2581 aagtcgaatg tgctctgaca ttatcttatt tagatattgg catacgaagc aaatcaggtg
     2641 ttagttcaaa agtaataaag aggtcaaatt taattagaac ctctaataat aatctttata
     2701 tgataaagtc tccatc
//
LOCUS       DAVKBC010000088         2490 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVKBC010000088 DAVKBC010000000
VERSION     DAVKBC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2490
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.088"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..471
                     /locus_tag="VWX64_001988"
     CDS             <1..471
                     /locus_tag="VWX64_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEU9191389.1"
                     /translation="IDLDNGKISLEFLENQLIDEMGHQYQDQIHELVWNWFNYVDLYD
                     EVYELIKQLKKKNFQIYVLSNTSSIFHILLDSVLSKVSSVLDGYVISCEVKMMKPQKE
                     IYLSLVNKYQLDIKDCIFLDDLEENVEAARTLGIKAFQIKERKEISNILKDLLN"
     gene            481..>2490
                     /locus_tag="VWX64_001989"
     CDS             481..>2490
                     /locus_tag="VWX64_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9191390.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIPIFEVDTYQSNKTLSSFDSDKIFEIVLEL
                     VRTEKLSNLYFISLTNEKEHSLFEYLTQKIKNSTHIQVQERLQLLSLYPTLKNFAKYD
                     CIFVDDEDLMHTLLDLFDWFTIIDRPKICLIGSRVWFEKRNLFYIHLDYRILALNTAE
                     NLESRNSSIVPVKDGKQILIDQLFDGECDDIYLLTVHSPMNKALEILSEKYKQISGKN
                     IKIIEKRYDELLEMIESGDVSSSFDMIRMDMAWLPTFGKKYFQEITSFRQTKSINQNI
                     SKSVSREYMYIDQKQYTFPLDVSSQILVYRKDLFEDSFLQRRYFEKTKRKLTVPKSYQ
                     EFDELSEFFTLTENPFSPTLYGHSLALSSSVRAACEFIPRFRERLAQSRMNLAVLPQV
                     LTEYEKSYQFTEKSFNSSWNDFVTNLNSGKTSMEIIFSNYTSPLFDGLNVSAQFEFAT
                     ATIPGNTPVIGGGSIGISKYSNRVEECLNFINWLYSEEISILLTSLGGFLPSKYVMQN
                     RMLQFQYPWLSSLEDTFSIGSRTKWYGFNTDFRFEQMLGQELIESV"
BASE COUNT          895 a          294 c          418 g          883 t
ORIGIN      
        1 attgatttgg ataatggtaa aattagttta gagttcttag agaatcaatt aatcgatgaa
       61 atgggacatc aatatcagga tcaaattcat gagttagtat ggaattggtt taactatgtt
      121 gatttatatg atgaagttta tgaattaata aaacagctaa agaaaaagaa ttttcaaatt
      181 tatgttttat caaatacctc ctcaattttt catattttat tagattctgt tctatctaaa
      241 gtatcatctg ttttagatgg ttacgtaatt tcttgtgaag ttaaaatgat gaaaccacaa
      301 aaagaaattt acttgtcatt agttaataaa tatcaattag atataaaaga ttgtatattt
      361 ttagatgatt tagaagaaaa tgtagaagct gcaagaactc taggtattaa agcatttcaa
      421 attaaagagc gtaaagagat ctcaaatata ctaaaagatc tcttaaacta gaggttaatt
      481 atggttacaa taaaagatat tgcaagagtg tctggagtct cacatgggac agtttcaaac
      541 gttttaaata aaaaaggtaa tgtctcagca gctaaaataa agttagtaga agagactgcg
      601 aaaaaattgg gttataatat gaattctcaa gctcagtttc ttcgaaaagg cgcttctagt
      661 aaatgttttt tcttgttatt taataatgca cgcaaaaagt atgctgagta ttttgcagaa
      721 attgatcagt tatctttaga tgtagaatat gtttacttac ataaattctc agagattaaa
      781 aataagatat ctgcaatttt aagtgaaaat cctcaattta tagtttgctt aggtttttct
      841 ccaaaaagat tcgttgatat tgaagataat attccgattt ttgaagtaga tacatatcaa
      901 tctaataaaa ctttatcttc ctttgatagt gataaaatat ttgagattgt acttgagttg
      961 gttcggactg aaaagctatc taatttatat tttatttcac ttactaatga aaaagaacat
     1021 tctttatttg aatatttaac tcaaaaaata aaaaactcaa ctcatataca agtgcaagaa
     1081 cgtttacaat tgttgtctct atatcctact ctaaaaaact ttgcaaagta tgattgtata
     1141 tttgttgatg atgaagattt gatgcacacg ctattagact tatttgattg gtttactata
     1201 attgatagac caaaaatatg tttgataggt tcacgtgttt ggttcgaaaa aagaaatctt
     1261 ttttatatac atttagatta tagaatattg gcactcaata ctgccgaaaa tttagaaagt
     1321 agaaatagtt caattgtacc agttaaagat ggcaaacaaa ttttaattga tcaattattt
     1381 gatggagaat gtgatgatat ttatttactt actgtccatt caccaatgaa taaagcctta
     1441 gaaattttat cagaaaagta taaacaaatt tctgggaaaa atattaaaat tatcgagaaa
     1501 agatatgatg aacttttgga gatgattgag tctggcgatg tttcatccag ttttgatatg
     1561 attagaatgg atatggcttg gcttccaaca tttgggaaaa agtattttca agagattaca
     1621 agctttagac aaacaaaaag tattaatcaa aatatttcta agtcggtgtc tcgagagtat
     1681 atgtatattg atcagaagca atatactttt ccattggatg ttagtagtca gattttagta
     1741 tatagaaaag acttatttga agattcattt ttacaaagac gatactttga aaaaacaaaa
     1801 agaaaattaa ctgtaccaaa aagttatcaa gagtttgatg agttaagtga attttttaca
     1861 ttaacagaaa atccattttc acctacactt tatggccata gtttagcttt aagttcttca
     1921 gtgagagcag catgtgaatt tattcctcgg tttcgtgaga gattagcaca atctagaatg
     1981 aatcttgctg tacttcctca ggttttaact gagtatgaga aaagttatca gtttaccgaa
     2041 aaatcattta attcttcgtg gaacgatttc gttacgaact taaacagtgg taaaacttca
     2101 atggaaataa ttttttcaaa ttatactagt ccattatttg atggtctcaa tgtttctgct
     2161 cagtttgagt ttgcaactgc cactatacct ggtaatactc ctgtgatagg tggtggctca
     2221 attggaattt ctaaatattc aaatagagtg gaagaatgtc taaactttat taattggtta
     2281 tattctgaag agatttctat tttactaaca tctctgggtg gttttttacc atcaaagtat
     2341 gtcatgcaaa ataggatgtt acaatttcaa tatccatggt tatctagttt agaagataca
     2401 tttagtattg ggagtagaac aaaatggtac ggctttaata ctgattttag atttgagcag
     2461 atgttagggc aagagttaat agaaagtgtg
//
LOCUS       DAVKBC010000089         2151 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVKBC010000089 DAVKBC010000000
VERSION     DAVKBC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2151
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.089"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..608)
                     /locus_tag="VWX64_001990"
     CDS             complement(<1..608)
                     /locus_tag="VWX64_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9191391.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRW"
     gene            1232..1414
                     /locus_tag="VWX64_001991"
     CDS             1232..1414
                     /locus_tag="VWX64_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU9191392.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            1424..1777
                     /locus_tag="VWX64_001992"
     CDS             1424..1777
                     /locus_tag="VWX64_001992"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU9191393.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYETKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIENKKQG"
     gene            1785..>2151
                     /locus_tag="VWX64_001993"
     CDS             1785..>2151
                     /locus_tag="VWX64_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU9191394.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLL"
BASE COUNT          799 a          356 c          359 g          637 t
ORIGIN      
        1 ttccaacggc atgactgaga acatccacca cggttggcat cacgcatact catgtggttt
       61 gaaagagtac aacgtccaga gtatgaaata cacatagctc catggacaaa ggcttcaatt
      121 tcaacatctg tacgtttgcg gatttcagct aattcttcca ttgaaacctc acgcgctaaa
      181 acgacacgag tcaagcctag ctctttccag aactcaaggg tttcatagtt agtggcactg
      241 gcttgggtag aaaggtggat ttcaaggcct ggtgcttcag tagctgcaat cataatcaag
      301 gctgggtcag atacgataac tgctgcaatc ccgatatcac gcagtttacg gaaccactca
      361 ccagcaccag cttcatttcc ttcgtgcata accatattag ccgctacata gaccttggca
      421 ccatacttgg ccgcaaactg cacgccttct tccatctgtt cgaaagtaaa gtttcccgca
      481 cggctacgaa gaccataggc ctgaccaccg ataaagacag catctgctcc atactgaaca
      541 gctaccttta gcttctctaa agtccctgca ggtgataaaa cctcaggacg ttttaatgtt
      601 tttgtcataa tttctcctat ttgcaatata aaagtttgac atttttcctt ctcattttat
      661 agtaaataaa ggataaaatc aagcctagac ggattgtttt gacaattcta atcttttaga
      721 ctttgcataa taactattaa acagtcgaaa attaccccag ttttaacaag tagtcaaaaa
      781 gtctaaaaaa gtaaaaacca gtatcccaag atactgactc gtaaaaatat ataaattagt
      841 ccttagatga ctactcccac tctgttgctc ctataatgga aaaggattga tacagtctag
      901 aatatcgctt ttttatttat tattctgata taaaactgtt agaattgatt ttttgtttta
      961 tacccaaata tgaatagaga cgtagctaat aagttgaata acatatttgg aaaaatgaga
     1021 aatagcaata ttactagaac ttttagaaac aatcaatatt taaaaagaaa aaagctcaaa
     1081 gaatttatta aaccatgtta taatagatat agctataatt ttatttataa caagaggata
     1141 gaaatgaccg aattagaaag aaaaaatcga aaaattagct aagaaatatt ctgataactt
     1201 aaacatcaaa gttcaagaga gagttcgtga aatggcaaat gataataaga gccattattt
     1261 gatatacaga gttttaggta tttcatttga agaaggagaa aatatcgatt tgtatcaaaa
     1321 taaaggtcgt tttttataca aatatgctgg ttcattttta gaagaagctg cagtactatc
     1381 ctttaacgaa aaatttggta cagaaaatac ttaaaaagtt aacattccta attctgaaag
     1441 tacaaaacct aagacttttg aaattgattg tttagtcgga gaaaaacacg catacgaaac
     1501 aaaatggtgg gatgcaacta cagatggaga ccatataact aaagaacaca ctagaataaa
     1561 agttattcat aacaaaggat atataccaat tcggttaatg ttctactatc caaatagaac
     1621 tcaagctata aaaattcagc aaactttaga aacattgtat aacggtattg gagggaaata
     1681 ttattatgga gattctgcct gggaacattt aagagcagtg accggtattg atttacttag
     1741 tattctaaca gatattgaaa ataaaaaaca ggggtaaaat caaaatgaca gtattaaaag
     1801 gagataactt agaaatatta aaaactattg aatcctcaag tattgattta atctatatgg
     1861 accctccttt ctttacacag aaaacccaaa aattatctaa taacaaaaat attatgtatt
     1921 cattcgaaga tacgtggact tcgattgagg attacaaaga atttttgtct gtaagattag
     1981 aagaatgcaa aagagtgcta aaaaatagtg gcagtatttt cgttcattgt gataaaattg
     2041 caaatcatca tattagatta attttagata atatctttgg agcagatatg tttcaaagcg
     2101 aaattatatg gaactataaa cggtggtcta attcaaaaaa gggattattg a
//
LOCUS       DAVKBC010000090         2062 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVKBC010000090 DAVKBC010000000
VERSION     DAVKBC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.090"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            15..932
                     /gene="adcAII"
                     /locus_tag="VWX64_001994"
     CDS             15..932
                     /gene="adcAII"
                     /locus_tag="VWX64_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU9191395.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQAGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQSKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            940..>2062
                     /locus_tag="VWX64_001995"
     CDS             940..>2062
                     /locus_tag="VWX64_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU9191396.1"
                     /translation="MKINKKYVAGSVAVLALSVCSYELGRYQAGQVKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEH
                     SQHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPK
                     NELSASELAAAEAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENI
                     SSLLRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEK
                     RIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAP"
BASE COUNT          678 a          394 c          444 g          546 t
ORIGIN      
        1 ttaaggagtt gttcatgaag aaacaaaatt tatttttagt cctgttaagt gtctttcttt
       61 tgtgcttggg ggcttgtggt caaaaggaaa gtcaggcagg aaaggggatg aaaattgtga
      121 ccagttttta tcctatctac gctatggtta aggaagtatc tggtgacttg aatgatgttc
      181 ggatgattca gtcaagtagt ggtattcact cctttgaacc ttcggcaaat gatatcgcag
      241 ccatctatga ttcagatgtc tttgtttacc attctcatac actcgaatct tgggcaggaa
      301 gtctggatcc aaatctaaaa aaatccaaag tgaaggtctt agaggcttct gagggaatga
      361 ccttggaacg tgtccctgga ctagaggatg tggaagcagg ggatggagtt gatgaaaaaa
      421 cgctctatga ccctcacaca tggctagatc ctgaaaaagc tggagaagaa gcccaaatta
      481 tcgctgataa actttcagag gtggatagtg agcataaaga gacttatcaa aaaaatgcgc
      541 aagcctttat caaaaaagct caggaattga ctaagaaatt ccagtctaaa tttgaaaaag
      601 cgactcagaa aacatttgta acacaacata cagccttttc ttatctagcg aagagatttg
      661 ggcttaatca acttggtatt gcaggcatct ctcctgaaca agaaccaagt ccacgacaat
      721 taacagaaat tcaggaattt gttaaaacct ataaggttaa aacgattttt acagaaagta
      781 atgcttcttc aaaagtagct gaaactcttg tcaaatcaac aggtgtgggt cttaaaactc
      841 tgaatccttt agaggcagac ccacaaaatg acaagaccta tttagaaaat ctggaagaaa
      901 atatgagtgt tctagcagaa gaattaaagt gaggaaagaa tgaaaatcaa taaaaaatat
      961 gtagcaggtt cagtggcagt tcttgcccta agtgtttgtt cctatgagct tggacgttac
     1021 caagctggtc aggttaagaa agagtctaat cgagttgctt atatagatgg tgatcaggct
     1081 ggtcaaaagg cagaaaattt gacaccagat gaagtcagta agagagaggg gatcaacgcc
     1141 gaacaaattg ttatcaagat tacggatcaa ggttatgtga cctctcatgg agaccattat
     1201 cattactata atggcaaggt tccttatgat gccatcatca gtgaagaact tctcatgaaa
     1261 gatccgaatt atcagttgaa ggattcagac attgtcaatg aaatcaaggg tggctatgtg
     1321 attaaggtag acggaaaata ctatgtttac cttaaggatg cagctcatgc ggataatgtc
     1381 cgtacaaaag aagaaatcaa tcgtcaaaaa caagaacata gtcagcatcg tgaaggaggg
     1441 acttcagcaa acgatggtgc ggtagccttt gcacgttcac agggacgcta caccacagat
     1501 gatgggtata tcttcaatgc atctgatatc attgaggaca cgggtgatgc ttatatcgtt
     1561 cctcacggcg accattacca ttacattcct aagaatgagt tatcagctag cgagttagct
     1621 gctgcagaag cctattggaa tgggaagcag ggatctcgtc cttcttcaag ttctagttat
     1681 aatgcaaata cagctcaacc aagattgtca gagaaccaca atctgactgt cactccaact
     1741 tatcatcaaa atcaagggga aaacatttca agccttttac gtgaattgta tgctaaaccc
     1801 ttatcagaac gccatgtgga atctgatggc cttattttcg acccagcgca aatcacaagt
     1861 cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat cccttatgaa
     1921 caaatgtctg aattggaaaa acgaattgct cgtattattc cccttcgtta tcgttcaaac
     1981 cattgggtac cagattcaag accagaacaa ccaagtccac aatcgactcc ggaacctagt
     2041 ccaagtctgc aacctgcacc aa
//
LOCUS       DAVKBC010000091         1905 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVKBC010000091 DAVKBC010000000
VERSION     DAVKBC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1905
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.091"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            44..1228
                     /locus_tag="VWX64_001996"
     CDS             44..1228
                     /locus_tag="VWX64_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histone-lysine N-methyltransferase"
                     /protein_id="HEU9191397.1"
                     /translation="MVKIYEETLRDGIQSSELSMLNTEDKKKVIKNFDNAGIEGCCIG
                     FINSSKKENDEINELFQFIITNKLKIVPAVLCRLLIEDFKEIKNIVQCNLFNQLKVYT
                     YIAVSPIRMKVENWSEEIIIEKIIDFLNYCQMENAKITIAFEDASRADKSFLKKLIEI
                     INNYPLVKSVVIADTVGTCNYNSTRDLVYFFRKNLFLSKTIEWHGHNDLGLAVSNALS
                     AIESGADIVHTCTLGIGERCGNTSTEQLIINLIVSECGRRATYKLRYLYDVAKILENK
                     SQFPISPKTPCFGMDSFFTCAGTHASSLYKSYLKNDNNFSIIFSPYDSNIFGREVTVG
                     INSQSGRSSIEYISRKYGLELSQENITSILGLVKQNDLFFREEEFVDYVKQKRVERLD
                     YK"
     gene            1152..>1905
                     /locus_tag="VWX64_001997"
     CDS             1152..>1905
                     /locus_tag="VWX64_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191398.1"
                     /translation="MTYFLGKRNLLIMLNKKEWKDLTISKSENDSIISCLYNWGFELP
                     KSKDYTFSLTWYGYNNVSYKYCEKECLTLGELSLLFPQLNDLFWENQKDNIEGRRNFY
                     KNCKNLLGKFNIYSVRDILEISDRDLQFALTNRVGSKEFENSIVSLMYINKLSDDNKA
                     ENTLEKKLYFSINNEDSIIPYYENTLGMTAGNYYFTASHRTFFSSTFPDFFKIDVPYK
                     ISNSVRNLTRNELRIRASEIIKSELANSENPIL"
BASE COUNT          711 a          213 c          341 g          640 t
ORIGIN      
        1 acttatctca tttaataatt gaagaaatct ctggagaata aatatggtaa aaatatatga
       61 agaaacttta cgagatggta ttcagagtag cgaactttca atgttgaata ctgaggataa
      121 aaagaaagtt attaagaatt ttgataatgc tggcatagaa ggatgttgta ttggttttat
      181 aaattcctca aaaaaagaaa atgatgaaat taatgaattg ttccaattta ttattactaa
      241 taagctgaag atagttccag cagttttatg taggttgctg attgaggatt ttaaagaaat
      301 taaaaatatc gttcaatgca atttatttaa tcaacttaag gtatacacgt atattgctgt
      361 cagcccaata aggatgaaag tggagaattg gagtgaagaa attatcattg agaaaataat
      421 tgactttctt aattattgcc aaatggaaaa tgctaaaata actattgcat ttgaagatgc
      481 ttctagagct gataaaagct ttttaaagaa gttaattgaa ataataaaca attatccttt
      541 ggttaagagt gtcgtcattg ctgatactgt cggaacttgt aattataatt caactagaga
      601 tctggtatat ttttttagaa aaaatttatt tttgagtaaa actattgagt ggcatggtca
      661 taatgattta ggacttgctg tctcaaacgc cttatctgct attgaatcgg gtgcagatat
      721 agtacatact tgcactctag ggattggaga aagatgtgga aatacttcaa cagagcaact
      781 gataattaat cttattgtaa gtgagtgtgg gagaagagca acttataaac tgagatattt
      841 gtatgatgtt gcaaagattt tagaaaataa atcacaattt ccaatatcgc ctaagactcc
      901 gtgttttgga atggattcct ttttcacttg cgcaggaaca catgcatcat cactttataa
      961 atcatatctt aaaaatgata ataatttttc aatcatattt tcaccatatg attctaatat
     1021 ttttggtagg gaggtgacag taggtattaa ttctcaaagt gggagaagca gtattgaata
     1081 tataagtcga aaatatggtt tagaattaag tcaggagaat ataacttcta tattaggctt
     1141 agtgaaacaa aatgacttat tttttaggga agaggaattt gttgattatg ttaaacaaaa
     1201 aagagtggaa agacttgact ataagtaaat ccgaaaatga tagtataatt tcctgcttat
     1261 ataattgggg attcgaactt cctaagagta aggactatac tttttcgtta acttggtatg
     1321 gatataataa cgtatcgtat aaatattgcg aaaaagagtg tttaacattg ggagaacttt
     1381 ctttattatt ccctcagtta aatgatttgt tttgggagaa tcaaaaagat aatatcgaag
     1441 gaagaagaaa tttttataaa aattgtaaaa atttattggg gaaattcaat atatattctg
     1501 ttagggatat tctcgaaata tcagatagag atttacagtt tgcactcact aatagagttg
     1561 gatcaaaaga atttgagaac tcaatagttt ctttaatgta tattaataag ttgtctgatg
     1621 acaataaagc tgaaaatact ctagaaaaaa aattgtattt ttcaattaat aacgaggata
     1681 gtataatacc atattatgaa aacactttgg ggatgacagc aggaaattat tactttacag
     1741 caagtcatag aacatttttt agtagtacat ttccagactt ttttaaaatt gatgtacctt
     1801 ataaaatatc taattctgtc agaaacctta ctagaaatga gttgaggatc cgagcatcag
     1861 aaatcataaa aagtgaatta gctaattccg aaaatccgat attaa
//
LOCUS       DAVKBC010000092         1809 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVKBC010000092 DAVKBC010000000
VERSION     DAVKBC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.092"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            114..1460
                     /gene="gdhA"
                     /locus_tag="VWX64_001998"
     CDS             114..1460
                     /gene="gdhA"
                     /locus_tag="VWX64_001998"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU9191399.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWNYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          569 a          338 c          371 g          531 t
ORIGIN      
        1 ccaaaaactg aattgaaaga atttttagaa aatttctgtt ttttctttac agtgaaaaaa
       61 aattctgcta taatgtctta tgtaataaaa tatgacaata aaaggagaac gatatgacat
      121 ctgctaaaga atatatccaa agcgtgtttg aaactgtgaa agctcgtaac gggcacgagg
      181 ctgaattcct ccaagctgtt gaagaatttt tcaacacttt agaacctgta tttgaaaaac
      241 accctgagta tatcgaagaa aatatcttgg cacgtattac tgagcctgag cgcgtgattt
      301 ctttccgtgt tccttgggtt gaccgtgatg gaaaagttca agtaaaccgt ggttaccgtg
      361 ttcaattcaa ctcagctgtt ggaccataca aaggtggact tcgtttccac ccaactgtaa
      421 accaagggat cttgaaattc ctcggatttg aacaaatctt taaaaatgtc ttgactggac
      481 ttcctatcgg tggaggtaaa ggtggatcag acttcgatcc taaaggtaaa acagatgctg
      541 aagtgatgcg cttctgccaa agcttcatga ctgaattgca aaaacacatc ggaccatcac
      601 ttgacgtacc tgctggtgat atcggtgttg gtggacgtga gattggttac ctttacggtc
      661 aatacaaacg tcttaaccaa tttgatgctg gtgtcttgac tggtaaacct cttggatttg
      721 gtggtagctt gattcgtcca gaagcaactg gttacggttt ggtttactat actgaagaaa
      781 tgctcaaagc taacggtaac agctttgctg gtaagaaagt cgttatttca ggttctggta
      841 acgttgctca atatgctctt caaaaagcaa ctgaactcgg tgcaactgtt atttctgttt
      901 ctgactcaaa tggttatgtc atcgatgaaa atggtatcga cttcgatctt ttggttgatg
      961 ttaaagaaaa acgtcgtgct cgtttgactg agtatgcagc tgaaaaagca actgcaacct
     1021 accacgaagg tactgtatgg aattacgctg gaaactatga cattgctctt ccatgtgcca
     1081 ctcaaaacga aatcaacggt gaagcagcta aacgtttggt tgctcaaggc gttatctgtg
     1141 tatctgaagg tgccaacatg ccgagcgacc ttgatgccat caaagtttac aaagaaaatg
     1201 gtatcttata cggacctgca aaagctgcca acgctggtgg tgtagccgtt tcagctcttg
     1261 aaatgagcca aaacagtctt cgcctctcat ggactcgtga agaagttgat gaccgtctca
     1321 aagacatcat gacaaacatc ttcaacacag ctaaaacgac ttcagaaaca tacggtcttg
     1381 ataaagacta ccttgcagga gctaacattg ctgcctttga aaatgtagca aacgctatga
     1441 ttgcccaagg tattgtttaa gatttatttg cttaatcctc aatcactacg attggggatt
     1501 tttagttgag ttagacagtt gggaaattct aattaaatga aataaaaact gaacaaattg
     1561 attgcggaat tcaaaccaat ttctaacata tttctagaaa ttaatttgac ttttctaatc
     1621 gatttgttca tatcttattt caatttacta tacttactta acccttttta tactcaatga
     1681 aaatcaaaga gcaaactagg aagcgagtcg caggctgtac ttgagtacgg caaggcaaag
     1741 ctgacgtggt ttgaagagat tttcaaagag tattaaacaa aaagaaaaaa cgctactcct
     1801 aagaatagc
//
LOCUS       DAVKBC010000093         1785 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVKBC010000093 DAVKBC010000000
VERSION     DAVKBC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1785
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.093"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            362..838
                     /locus_tag="VWX64_001999"
     CDS             362..838
                     /locus_tag="VWX64_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9191400.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            838..1599
                     /locus_tag="VWX64_002000"
     CDS             838..1599
                     /locus_tag="VWX64_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU9191401.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFVGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLRVGEKRLNELLEK"
BASE COUNT          660 a          236 c          345 g          544 t
ORIGIN      
        1 aaaaacaaca ctttattgag gtattggata cgctttgcta atagcctaat aatcacatgt
       61 ggagtgttgc tacaacgaaa aaggtgataa tccttgattt caagctattt tataagcatt
      121 ttgtctttgt agataaaggc aattttgaca ataaaaatcc taaaaggtga atcgttatag
      181 atgtatttgt agatatcgtt tgcgcatcga aaaaattaat acaataataa atatttatgg
      241 ctctttaggt gacttttata gaagtaaagt ttaggataga aaaacaagaa ataatgcacc
      301 atttttggtg cgttatgctt ttttatgcta taatggattt ataaaaataa aggagtttgc
      361 catgattgga aagaacataa aatccttacg taaaacacat gacttaacac aacacgaatt
      421 tgcacggatt ataggtattt cacgaaatag tctgagtcgt tatgaaaatg gaacgagttc
      481 agtctctacc gaattaatag acatcatttg tcagaagttt aatgtatctt atgtcgatat
      541 tgtaggagaa gataaaatgc tcaatcctgt tgaagattat gaattgactt tgaaaattga
      601 aattgtgaaa gaaagaggtg ctaatctatt atctcgactc tatcgttatc aagatagtca
      661 gggaattagc attgatgatg aatctaatcc ttggatttta atgagtgatg atctatctga
      721 cttgattcag acaaatatct atttagtaga aaattttgat gaaatagaga gatatagcgg
      781 ctatttggat ggaattgaac gtatgttaga gatatctgaa aagcggatgg tagcttaatg
      841 gaaatccaag attatactga tagtgaattc aaacatgctt tagcaaggaa tcttcgttca
      901 ctgacaagag gaaaaaagtc cagtaaacaa cctatagcga ttttgcttgg aggtcaaagt
      961 ggtgccggta agactacaat tcatcgtatt aaacagaaag aatttcaagg aaatattgtt
     1021 atcatagatg gtgatagttt tcgttctcag catccacact atttagaact gcagcaagaa
     1081 tatggcaaag acagtgtaga atataccaaa gattttgtag gaaaaatggt agagtcttta
     1141 gtaacaaaat tgagtagttt gagatacaat cttttgatcg agggaacttt acgaacagtt
     1201 gatgttccaa agaaaacagc acaactcttg aaaaataagg gatatgaagt acaattggcc
     1261 ttaattgcga caaagcctga attgtcgtat ctaagtactc ttatccgtta tgaagaactg
     1321 tacattatca atccaaatca agcacgcgca actccaaaag aacatcatga tttcattgta
     1381 aatcatctag ttgataatac acgacaattg gaagaactag ctatttttga aagaattcaa
     1441 atttaccaac gagatagaag ttgtgtatat gattcaaaag aaaatacaac ttcagcagca
     1501 gatgttcttc aagagttact ctttggggag tggagtcagg tagagaagga gatgttgagg
     1561 gtaggggaaa agagacttaa tgaattactt gaaaaataaa caattgatat ttttaggaga
     1621 atagaaatga gagggtttaa taacaagata aagtctgttt atcaagaact aacaaattcc
     1681 aaagagaaat tcggtagctt tcacaagact ttaattcatt tgcatacacc tgtttcttat
     1741 gattacaagc tattttctaa ttggactgca acgaaatata gaaaa
//
LOCUS       DAVKBC010000094         1772 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVKBC010000094 DAVKBC010000000
VERSION     DAVKBC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1772
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.094"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            10..1602
                     /locus_tag="VWX64_002001"
     CDS             10..1602
                     /locus_tag="VWX64_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9191402.1"
                     /translation="MKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMNLERFLKLS
                     IYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHSKSSGTYLS
                     WLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLMIMLLVPKI
                     FASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAGILLKMVIQ
                     RKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTGVIFTALGE
                     LGGQLSSIIGTKPIVLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNICYKYGDKEI
                     LKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIKKTSYLNMV
                     SNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNILDYYVGDD
                     GRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDREDLTVIIVT
                     HAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          624 a          210 c          326 g          612 t
ORIGIN      
        1 aaatcaaata taaaaaaatt tagtttatta acgatattta ttgttgctgg tcaattattg
       61 ctaatttatg cagcaactat taatgctctg gtgttgaatg aattaattgc gatgaattta
      121 gagcggtttt tgaaattgtc aatctaccaa atgattgtct ggtgtgggat aatattcctt
      181 gactgggtag tgaaaaatta tcaggttgaa gtgatccaag agtttaatct agagattcga
      241 aatagagttg ccacagacat ctctaactct acctatcaag aatttcatag taaatcatca
      301 ggaacatatc tttcgtggct aaataatgat gttcagactt taaatgatca ggcttttaaa
      361 caactttttt tagtaataaa aggaatttct ggtactatat ttgcagttgt gactcttaat
      421 cactatcatt ggtcattgac tgtagccacc ttgttttcat taatgattat gctacttgta
      481 ccaaaaatct ttgcatcgaa aatgcgagaa gttagtctaa atttaactag ccaaaatgaa
      541 gcttttttaa aatctagtga gactatattg aatggatttg atgtgttagc gtccttgaat
      601 cttttatatg tattgcctaa gaaaattaaa gaagcaggaa ttttattaaa gatggttata
      661 caaagaaaga caactgtaga aacgttagca ggcgctatta gcttctttct caatattttt
      721 tttcagatat ctctcgtttt tttaacaggc tatcttgcaa taaaaggaat agtgaaaatt
      781 ggtactattg aagcaatagg agcactaaca ggtgttattt ttacagcgct aggtgaatta
      841 ggaggtcaat tatcctctat tattggtacg aagcctattg ttttaaaatt gtattcaatt
      901 aatccaattg agtcaaataa aatgaatgat atcgaaccaa atgaggtgaa tagagatttt
      961 ccgttatatg aagcaaaaaa tatttgctat aagtatggag ataaagaaat attaaaaaac
     1021 ttaaattttt gttttcaacg taatgaaaag tatttaattt taggtgaaag tggaagcggg
     1081 aaatctacat tattaaaatt attgaatggc tttttgagag attatagtgg agaattgcga
     1141 ttctgcgggg atgatataaa aaaaacctcc tatttaaata tggtttcgaa tgttctatat
     1201 gtagatcaaa aagcttattt gtttgaaggt acgattagag ataatatttt attggaagaa
     1261 aattatactg atgaagaaat actacagtct ttagaacaag ttggtttgag tgtaaaagat
     1321 tttcctaata acattttaga ttattatgtt ggtgatgatg ggagattact gtcaggaggg
     1381 cagaaacaaa aaattacttt agctagaggc ctaattagaa ataagaaaat agtattaatt
     1441 gacgagggaa cttctgctat cgataggaga acttcgttag cgattgaacg taagatatta
     1501 gatagagagg atttgactgt cattattgtt acccatgctc cgcatccgga acttaaacaa
     1561 tattttacta agatatatca atttccaaag gattttattt aagaatatag gggagggaaa
     1621 catgagattc tattgtgaag cttatgaggt aattactgaa gagaaaaaag tatcattttt
     1681 ttatgtagat gagaaaccct taaggtatct gttatttgac tatatatttc tactagttct
     1741 agctaaaaaa aaatatctca atcttatgaa ct
//
LOCUS       DAVKBC010000095         1755 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVKBC010000095 DAVKBC010000000
VERSION     DAVKBC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1755
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.095"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            109..917
                     /locus_tag="VWX64_002002"
                     /pseudo
     CDS             109..917
                     /locus_tag="VWX64_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            934..1512
                     /locus_tag="VWX64_002003"
                     /pseudo
     CDS             934..1512
                     /locus_tag="VWX64_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1525..1695
                     /locus_tag="VWX64_002004"
     CDS             1525..1695
                     /locus_tag="VWX64_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191403.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT          642 a          251 c          351 g          511 t
ORIGIN      
        1 agaaaagtgc aaataagaaa tctccagatt aggaactatc cgtgagttct ctagtctgga
       61 gatttttcaa tagacttcct gcgaaacaaa atatggtata atagttctat gaatgatgaa
      121 gcaagtaaac aactaaccga tgcacgattt aagcgtcttg ttggtgttca acgcacgact
      181 tttgaagaga tgttagctgt attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga
      241 cgaaaaccta aattaagcct agaagacttt cttatggcca ctcttcaata tgtgcgagaa
      301 taccgcactt atgaagaaat tgcggctgat tttggtatcc acgaaagcaa cttactccgt
      361 cggagccaat gggttgaagt aactcttgtt caaaggtggt gttacgattt caagaactcc
      421 tctcagttct gaagacacgg taatgattga tgcgacggaa gtaaaaatca atcgccctaa
      481 aaaaaaaaca attagcgaat gattctggta aaaagaaatt ttacgctatg aaggctcaag
      541 cgattgtcac aagtcaagga agaattattt ctttggatat cactgtgaac tattgtcatg
      601 atatgaagtt gttcaaaatg agtcgcggaa atatcggaca agctggtaaa atcttggctg
      661 acagtaatta tcaagggctc atgaagatat atcctcaagc acaaactcca cgtaaatcca
      721 gcaaactcaa gccgctaata gctgaagata aagcctataa ccatgcacta tctaaggata
      781 gaagcaaggt tgagaacatc cttgccaaag taaaaacgtt taaaatgttt tcaacaacct
      841 atcgaaatca tcgtaaacgc tttggattac gaatgaattt gagtgctggt attatcaatc
      901 atgaactagg attctagttt tgcaggaagt ctattatcaa aaataccatc aggattatat
      961 aagattgata caggaaaagt tttatttgat ggtgtaaata ttaatcaaat agataaaaaa
     1021 atattaagtc aaaatttagg agtagttcca caggattcgt ttttattgaa cagaagtatt
     1081 cttgataaca taactttaaa gcacgaagtt acttcacaaa agatagagga agtttgtaaa
     1141 gcagttcaaa tctatgatga aatcatggct atgccgatga aatttaatac tatcatctca
     1201 gagatgggtt caaatatttc aggtggtcaa agacaacgga tagcactggc acgtgcatta
     1261 ataaataatc ctagtattgt aattttagat gaagcaacta gtgctttaga cactattaat
     1321 gaggaaagaa taacaaagta tataaaaagt cagggctgta ctcaaataat tgtagctcat
     1381 agattgtcaa cgattaagga tgcggatatt attgttgtaa tgaaaggtgg taagattgtt
     1441 gagtcaggaa atcataagta cttaatggat cttggtggag agtactacag cttatataca
     1501 aaaaggaaat gaggtgtaaa gaaaatgaag aaagaaaatg aatatgtaat tttaacaaca
     1561 gcctcactag gggtgatgat tggaatagtg tttgcaattt ttttagattt tccagttgaa
     1621 tatggtattt ctttaggatt gttgaatgga atagtattgg gttcgctgat tgtttacaaa
     1681 aacaataaga attaagcata attttttgct gtaaactaag gagtagagat ggctatagtt
     1741 gaaattataa atcta
//
LOCUS       DAVKBC010000096         1673 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVKBC010000096 DAVKBC010000000
VERSION     DAVKBC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.096"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            72..527
                     /locus_tag="VWX64_002005"
     CDS             72..527
                     /locus_tag="VWX64_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9191404.1"
                     /translation="MQWQTQLSEKKANTDYIARYGVYAVIPNPEQKQIVLVQEPNGAW
                     FLPCGEIEAGENHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLY
                     EATPFKEVQKPLENFNHIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            692..991
                     /locus_tag="VWX64_002006"
     CDS             692..991
                     /locus_tag="VWX64_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU9191405.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1252..1575
                     /gene="tnpB"
                     /locus_tag="VWX64_002007"
                     /pseudo
     CDS             1252..1575
                     /gene="tnpB"
                     /locus_tag="VWX64_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          568 a          330 c          292 g          483 t
ORIGIN      
        1 gattatacca cattgtgtac tatttttggt tcatttcact ataataataa cgatactaga
       61 taatgaggaa aatgcaatgg caaacccaac tttcggagaa aaaagcgaat acagactata
      121 ttgctcgcta tggcgtatat gcagttatcc ctaatcctga acaaaaacaa attgttcttg
      181 ttcaagaacc aaatggtgct tggttcctac catgtggaga aattgaagca ggtgaaaatc
      241 atcaggaagc cctaaagcgt gagttgattg aagagcttgg tttcacagca gaaattggta
      301 cctattacgg acaagctgac gaatatttct attctcgtca tcgtgatacc tactactaca
      361 atcctgccta cctctatgaa gcaactcctt tcaaagaagt acaaaagcca ctagaaaact
      421 ttaatcatat tgcctggttc cctattgacg aggctatcaa aaaccttaaa cgtggtagcc
      481 ataaatgggc cattgaatct tggaaaaaac agcataagat tgactaatac tcaatgaaaa
      541 taaaattcaa accacgtcag cgtcgcctta ccgtactcaa gtatagcctg cggctagctt
      601 cctagtttgc tcttttattt tcattgagta taaatcaagc gactttattc aaaaagtgct
      661 ataatagaat tagaaaatcg gaggaaatat tatgaagctt atcaatacga caaactcaca
      721 ctcgcaactt gtaaaaagtc agctagaaag taccgatgca acccttgttg aggtttattc
      781 tgcagggaat acagatgtta tttttaccca agctccgctt cactatgaaa tcctcatctc
      841 aaacaaacac cgtgctattc gtgagcctga aatcgaaacc attcaagaat ttttcttgaa
      901 acgtaaaatt gataagacct ctgttgatga agccaatatc aagacactct actcagagaa
      961 attaattgga atttcaatcc caatcaagta agaaaattga gtaaaaactc gatttgagag
     1021 aaagtccaat aagtctttcc ataataaaac gcatagtagc aagagtttct acacccacta
     1081 ttatgcgttt ttatcatttt gaaatctact gctaatcaat gaagaagcaa agatcaaact
     1141 aggcagctag ttacaagtta cgtaagcgcg tcataacaag gtatctatcc taattcccca
     1201 acttccagta tactagataa aaaataatta tcggaggaaa ggtattgtac tatgataatt
     1261 caactaagtg atttaggtca agttcacctt gtttgtggca agacagatat gaggcaggga
     1321 atagactcat tagcctatgt agttaaaacc cactttgaat tggatccttt ctccggtcaa
     1381 gcctttctct tttgtggtgg acgtaaagac cgctttaaag ccctttactg ggatggtcaa
     1441 ggattttggc tactatataa acgctttgag aacggaaaac tgacttgacc aagtacagaa
     1501 aaggatgtca aagctctcac accagaacaa gtagactggc ttatgaaggg cttttctatc
     1561 actccccaaa tatagtggat ttaaactaga atagtacacc cctacttcta aaacattgtt
     1621 agaaatcgat ttgactgtcc tgatcaattt gtcctgttct tgtttcattt tac
//
LOCUS       DAVKBC010000097         1609 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVKBC010000097 DAVKBC010000000
VERSION     DAVKBC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1609
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.097"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            54..737
                     /locus_tag="VWX64_002008"
     CDS             54..737
                     /locus_tag="VWX64_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000507009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191406.1"
                     /translation="MGFSPGVAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYD
                     KPLLLPLIPFSIIIALVQKLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKL
                     QSKSELPCVALSYISLIKPYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLY
                     LRHYNEKNKYESMLKKILEVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYM
                     GIKHVSIRR"
     gene            1114..1488
                     /locus_tag="VWX64_002009"
     CDS             1114..1488
                     /locus_tag="VWX64_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU9191407.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLGRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
BASE COUNT          552 a          208 c          290 g          559 t
ORIGIN      
        1 ttgtgatcat tataggagct aggaaatact atcgaattct ctttcaccaa ctaatgggat
       61 ttagtccagg agtagcagtg ttttataagg agagtcaaac aactaagaat ctgtttaaat
      121 tttactactt cttgtacttt acaacactaa tttcatacta ttttttcttt acttttgtgt
      181 atgacaaacc gttgcttttg cctcttattc cattttctat tatcatagca ttagtacaaa
      241 aactttatag aattgagaat caacaattat ttctattaaa atcaaaggta ctaacaatac
      301 tggaatctaa gagggattgt gagtttaatc ttcaggatta tcatgaaatt tggaaattgc
      361 aatcaaaatc tgagttgcca tgcgtggctt tatcttatat cagtttgatc aagccatatc
      421 tttcagagag cgtgcgtgaa caaattgatt tattagaagt taagcgattt aaaaaaataa
      481 atcatccaat atcactttat ggtatgttgg atgttataaa attaaatcta tatttacggc
      541 attataatga aaaaaataaa tatgaatcaa tgttaaagaa aattttagag gtaagaccag
      601 actttgtttt aatcgagcag aatattgatg atagtttaaa tagctcgcaa ccattatctt
      661 tatctttagc catttcagaa atccaacttt tgcttgaagt gtatatgggg atcaaacatg
      721 tttcaattag gagataaaac cagaataata tttgccatta taggggcaag ttgcatatta
      781 gtcagtatgt atcttatacc tctcattaac acggataata aattttggga aatactttta
      841 tttataatag gtgtattgct aattggaatt gcgttactaa gtcaaaaaaa ataaattttg
      901 aaatagtatt agtgagttcg caatcattta ttgctagtgg tttagaactg ttaagtttca
      961 aacaataatt gattttaaac cttaggtaac ctataaaaac aaataaggta gagaaaggat
     1021 atcttatcta ggtagctaag tgataaaaac acagtcgtct atcacttgtt aggaaactat
     1081 cctaactatg cttaataaaa aaggagaaaa taaatggaac tcgtattacc aaataattat
     1141 gttgctcttg agcaagaaga gatgatgtat cttgatgggg gattttctat tccgagatgg
     1201 cctgttgcaa cagccattaa tatagctttt aatggtgttt taggtggagg agcaatcagt
     1261 ctagttagaa attatattcg taattatggt ttggggcgag ttacaagcgc aattgctgga
     1321 gcagctgcaa gatatgttgg ggtacgagtt gcaaatagag tggcaggatt tgcactgtct
     1381 gctattaatg gatttgcagc ttggatgtca attggtgatg ctattacaac aatctgggcc
     1441 aataatgatg taaataggag agacccaaat ttaaacgcct tgtggtaact agatatgggt
     1501 attaaaatgg aaaaaatttt tgttattatt ttttttgtat gtctatttat atcatccata
     1561 acttttttag cctatgattt tgttagcgaa gaaataaaaa aattgatta
//
LOCUS       DAVKBC010000098         1464 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVKBC010000098 DAVKBC010000000
VERSION     DAVKBC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1464
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.098"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..752
                     /locus_tag="VWX64_002010"
                     /pseudo
     CDS             1..752
                     /locus_tag="VWX64_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            745..>1464
                     /locus_tag="VWX64_002011"
     CDS             745..>1464
                     /locus_tag="VWX64_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9191408.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKY"
BASE COUNT          545 a          138 c          294 g          487 t
ORIGIN      
        1 cttgacttat tttgattttt ggacatattc tatgggagat gcttttattt gtgtatctga
       61 aactatgaaa aaaagattgg agagtataat aaaaaaataa gaagatagtt gcaataaata
      121 acggaattaa tgtatcaaat agcgatttag atgtagtagg tgttcaagac tttaaaaaag
      181 aattttgtat tccaaataac aaaaaaatca tttgttatgt tggaaggttg gatccagaaa
      241 aaaggccgga tagattcctt gaatttgcag aaaaattatt tttagtcaga gaagatgtga
      301 tttttattat ggctggaaat ggtagtatgt gggctgcttt gaaagaaaaa atttgccatt
      361 tgaaatgtag agataatttc aggttacttg gtgaaatcta tccagctact atagtttacc
      421 aaatatcgga tttattgtat attccttatg atacagaagg aatacctatg tgtgttttag
      481 agtcaatgtc acaaggaact ccggttttag ctagtaatgt tggcgggtta agtgaaatta
      541 ttgaacatag ggttgatgga tttttatttg agaaggaaga tgttgaggga gtgtgtgctt
      601 gtgctaattt tttactcaat gattctgagt atttgaaata tataggtgag aatagtaaat
      661 caaaaataag aaaacatttt tctgtgcaaa aaatgttttt agaaaccatg agagtatatg
      721 atgaattatt agagaagagt agtcatggat aggaatatag atcaagaatt agtaagtatt
      781 ataataccaa cacataatag gtatgaatct ctgattagag ctgtgaaaag ttgtttacat
      841 caaagttata aaaatatcga agttataatt attgatgata attatagtaa tgtaaattta
      901 agaaataaaa ttatccatca atttggctat accaatcata gaattaagtt aattttaagt
      961 aatgaagatt taggtgcaac taatgccaga aacataggta taaaaaattc tagaggtaag
     1021 tatatatcat ttttagacga tgatgatgaa tatatgccag atcgaatttt aaagttgatg
     1081 gcttgtttta aaaagagtag aatgaagaat ttagctttag tttatagtta tggaataata
     1141 atttatccaa atggtacacg agaagaggag aagaccgatt ttgttggaaa tcccttgttt
     1201 gttcaaatgg ttcacaatat agcaggtacg tcattttggt tgtgtaaaaa agaggtgcta
     1261 gaattaatta atggttttga gaaaatagat tcacatcagg acggtgttgt tttattaaaa
     1321 ctacttgctc aaggatacca aattgatata gtgcgagaat tcttggtgaa ttactacgct
     1381 cacagtaaag aaaacggtat cactggagtg acacaaaaaa caattaatgc agatgaagaa
     1441 tattataatt actgtaggaa atat
//
LOCUS       DAVKBC010000099         1442 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVKBC010000099 DAVKBC010000000
VERSION     DAVKBC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1442
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.099"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..1270
                     /locus_tag="VWX64_002012"
     rRNA            <1..1270
                     /locus_tag="VWX64_002012"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            1347..>1442
                     /gene="rrf"
                     /locus_tag="VWX64_002013"
     rRNA            1347..>1442
                     /gene="rrf"
                     /locus_tag="VWX64_002013"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          389 a          308 c          424 g          321 t
ORIGIN      
        1 accgcaaacc gacacaggta gtcgaggcga gtagcctcag gtgagcgaga gaactctcgt
       61 taaggaactc ggcaaaatga ccccgtaact tcgggagaag gggtgctgac tttaagtcag
      121 ccgcagtgaa taggcccaag caactgttta tcaaaaacac agctctctgc taaatcgtaa
      181 gatgatgtat agggggtgac gcctgcccgg tgctggaagg ttaagaggag tgcttagcgt
      241 aagcgaaggt atgaattgaa gccccagtaa acggcggccg taactataac ggtcctaagg
      301 tagcgaaatt ccttgtcggg taagttccga cccgcacgaa aggcgtaatg atttgggcac
      361 tgtctcaacg agagactcgg tgaaatttta gtacctgtga agatgcaggt tacccgcgac
      421 aggacggaaa gaccccatgg agctttactg cagtttgata ttgagtgtct gtaccacatg
      481 tacaggatag gtaggagtct aagagatcgg gacgccagtt tcgaaggaga cgctgttggg
      541 atactaccct tgtgttatgg ccactctaac ccagataggt gatccctatc ggagacagtg
      601 tctgacgggc agtttgactg gggcggtcgc ctcctaaaag gtaacggagg cgcccaaagg
      661 ttccctcaga atggttggaa atcattcgca gagtgtaaag gtataaggga gcttgactgc
      721 gagagctaca actcgagcag ggacgaaagt cgggcttagt gatccggtgg ttccgtatgg
      781 aagggccatc gctcaacgga taaaagctac cctggggata acaggcttat ctcccccaag
      841 agttcacatc gacggggagg tttggcacct cgatgtcggc tcgtcgcatc ctggggctgt
      901 agtcggtccc aagggttggg ctgttcgccc attaaagcgg cacgcgagct gggttcagaa
      961 cgtcgtgaga cagttcggtc cctatccgtc gcgggcgtag gaaatttgag aggatctgct
     1021 cctagtacga gaggaccaga gtggacttac cgctggtgta ccagttgtct tgccaaaggc
     1081 atcgctgggt agctatgtag ggaagggata aacgctgaaa gcatctaagt gtgaaaccca
     1141 cctcaagatg agatttccca tgattatata tcagtaagag ccctgagaga tgatcaggta
     1201 gataggttag aagtggaagt gtggcgacac atgtagcgga ctaatactaa tagctcgagg
     1261 acttatccaa agtaactgag aatatgaaag cgaacggttt tcttgaattg aatagatatt
     1321 caattttgag taggtattac tcagagttaa gtgacgatag cctaggagat acacctgtac
     1381 ccatgccgaa cacagaagtt aagccctaga acgccggaag tagttggggg ttgccccctg
     1441 tg
//
LOCUS       DAVKBC010000100         1328 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVKBC010000100 DAVKBC010000000
VERSION     DAVKBC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1328
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.100"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(552..737)
                     /locus_tag="VWX64_002014"
                     /pseudo
     CDS             complement(552..737)
                     /locus_tag="VWX64_002014"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          424 a          170 c          233 g          501 t
ORIGIN      
        1 ttcttaatta gctcgtatct ataggatgat actgaaaatc ttcttgttgc tttaaatcac
       61 aatcgaaaaa ttctgttttt catcttagaa aagaatgttt agaaatgtaa aatgaacctt
      121 ttttcttatc cgaaaacctt actaaagtat ataatttagg aagtcaattc tgtatgataa
      181 tgtttgtact atcgtcgagt ttttgcttga ttgcctaacg agataaattt tagaagagtt
      241 ttcggtgtga tttgacaagt ttctgactgg aaggatagtt acactagtat tgtttattaa
      301 aatgagcaga tagagaaaat ttggaatcta tttgcttatt atcaatcgtt ttttagctta
      361 tttgtcttag attggtatag aactgagcta tggattaatc ttcttgtatc ttatcctgtt
      421 cctaaatatg ttggtagaaa aatgaagcag ttgttacgag tgtctgtatt ggaaaaaaat
      481 tttgtctata caattcttta aatgatatga agactaggaa tgccaaaaca ctgacatatt
      541 tcgtttaaag cctatccagt ctcttcaatt gtatttgtag aaatgctatc agtaatatat
      601 tcgcgaacac tatgatttac aacagtgtgg tcgtacatct ttgtaacttt attatacaac
      661 aaccatttac aggtgtaaag ttgagcagtg tctttagtaa atttagggac ttgttttgtc
      721 atagttttga tacctgtatt cgttgtttca tgagtatttg acgtttcttt tcatgtaggc
      781 atttcaacaa ttagaatgat atttttccga ggatgagctt atatattgtg actttttaga
      841 gttatgatgc ctcttgattt gactatcgct atcaatttca tccactttta cagtttcatg
      901 gttttatgaa ccgaaacatc taggtacagg ttttagcatc aattgattgt ttttgagcca
      961 tatgaagttg aaacgtggag atgcttttct tgtgataacg ccctattcaa agaggaataa
     1021 ccgtttttgg agagagttca gtactatgtg gcgctaaata ctatatgtaa aacatatatt
     1081 aaacaagatt taactaagga gaattgtaaa aacaaaaatg agaatttcat ataaagttta
     1141 ttctaggagt atgtatcttg aataaaaatc gttatttaag ttcagggtta tgatgaatgt
     1201 ttttataata ataaaatgca gctagaagaa aagttatttt aatataaatc actcaacata
     1261 gagagaaggc ggtttcctat atggaagtcg tcttgttttc atattgtcta aatacgagat
     1321 atctacta
//
LOCUS       DAVKBC010000101         1301 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVKBC010000101 DAVKBC010000000
VERSION     DAVKBC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.101"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..815
                     /locus_tag="VWX64_002015"
                     /pseudo
     CDS             1..815
                     /locus_tag="VWX64_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(850..1059)
                     /locus_tag="VWX64_002016"
                     /pseudo
     CDS             complement(850..1059)
                     /locus_tag="VWX64_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1225..1298)
                     /locus_tag="VWX64_002017"
     tRNA            complement(1225..1298)
                     /locus_tag="VWX64_002017"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1262..1264),aa:Asn,seq:gtt)
BASE COUNT          434 a          270 c          206 g          391 t
ORIGIN      
        1 agtataaaaa aattcaaact agaattcttc ttagaaaagg ccgttttaag tgctatcatt
       61 gctcaaaaat ggagctcgct gagacttcta tcgtcaagaa gaatcatcaa attccttgta
      121 tcatcaacca aaagattgct cagaagctaa ttaaaaagac ttctatgacc gacattgatc
      181 atcagttgtc tatttcaact tcaactgtca ttcgcaagat caatgatttt cactttgagc
      241 atgatttttc gcgtcttcct gagattatgt cctaggacgt tgaaacagtc cggggagtga
      301 ctgtttcaat cgggagatgg agatgagctt tattgctcaa gactttgata agctcaatat
      361 cataactgtt cttgagagca gaacacaagc catcatccga aatcccatga atacaaggct
      421 atcaagcgat actgaaagct cattcaacaa gatagtcaga aactgagtga taaacgattt
      481 tatcgcccta cttttcgtat gcacttgact aataaagaaa ttctagataa acttttgagc
      541 tattccgaag acttgaaaca ccactataat ctctaccagc tcttgctttt ccacctcttt
      601 ttcagactct gtttaaaacc ttcctcaaag ataaagagaa aatcgtcaac gcccttcaat
      661 taccttattc caacgccaaa ctggaagcca ccaataatct catcaaactt atcaagtaca
      721 atgcctttgg ttttaggaac tttgaaaact tcaaaaaaga aaggacgaaa tttgtccttt
      781 ctagatcttc gctttcttca acccactaca gttgacaaag aaccgaaaaa tgtctcgcct
      841 ctaatatagt caattgaaac aagaacaaga caaaagagcc tcataaaagg tattgcaact
      901 tggtaatacc tttttggggt tctttttgat atgaacccat gttttctcaa taggattgta
      961 ctcaggtgag tagggaggaa gaggtaaaag tttatgccca aactcttcac acaagagttc
     1021 tagcttaccc attctatgga atcttgcatt gtccataata tagtagattg aaactagaat
     1081 agtacacctc tacttctaaa acattgttag aattcgattt tactgtcctg atcgatttgt
     1141 cctattctta tttcatttta ctataacacg aaatagatta ttattacata acaaaaaaga
     1201 ggtctaaacc tcttaactaa attactccgc cagtaggact cgaacctacg acatcatgat
     1261 taacagtcat gcgctactac caactgagct atggcggatt a
//
LOCUS       DAVKBC010000102          846 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVKBC010000102 DAVKBC010000000
VERSION     DAVKBC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.102"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(296..607)
                     /locus_tag="VWX64_002018"
     CDS             complement(296..607)
                     /locus_tag="VWX64_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9191409.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(622..>846)
                     /locus_tag="VWX64_002019"
     CDS             complement(622..>846)
                     /locus_tag="VWX64_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEU9191410.1"
                     /translation="DQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIKVPQ
                     PVQSGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT          266 a          155 c          145 g          280 t
ORIGIN      
        1 ttccaacggc atgactgaga acatccacca cggttggcat cacgcatact ctagacggat
       61 tgttttgaca attctaatct tttagacttt gcataataac tgttaaacag ttgaaaatta
      121 acccagtttt aacaagtagt caaaatacca gataaaggaa aaaagtcttt aaaatcttaa
      181 aaacgcatag tatcaggtat tgaacaatct tgatattatg cgttttattg tgggaagatt
      241 tacttcattt tctcttggaa ttgagttttc tcctacttca aaactagatg atttgctatt
      301 taaaatagcg ttccttatga ttttggcaac ctggattaaa gcgagaaaaa caaaaggggc
      361 aacttaaact ttctttatat tgcttatatg ttagtagttt tagacaaaca ccacataaaa
      421 taggcttatc ctgtatcaaa gataagggat acggctcaaa agggtgattt tctaatgaat
      481 catgacaccg ataacaagca tagtactttt tacaatcata gcattgtaaa gcaataatat
      541 ccagcttgct atggtaatga atgcatcttg tttgcttatc cactaagaaa ccctgtgcct
      601 ctatcatttc cttttccttt cttaagctcg aactgtgacg ctggttccat cttccttata
      661 aagattgatg agtccttctt ttaatgcacg aaccatgtct cctgattgaa cgggttgtgg
      721 gactttaata gtcaatagtt ccattggatt tggagcgcgg tcgattttat tgcctttggc
      781 atcatgcaaa tcttcaatat aggtttcaaa atgacggaaa cctggaccat aaaactcaac
      841 ttggtc
//
LOCUS       DAVKBC010000103          838 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVKBC010000103 DAVKBC010000000
VERSION     DAVKBC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.103"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            70..459
                     /locus_tag="VWX64_002020"
     CDS             70..459
                     /locus_tag="VWX64_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HEU9191411.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFL"
     gene            432..>838
                     /locus_tag="VWX64_002021"
     CDS             432..>838
                     /locus_tag="VWX64_002021"
                     /inference="COORDINATES: protein motif:HMM:NF027704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU9191412.1"
                     /translation="MVLLGYLPIKSPVKKELLEMLRDSGLNVMYMPIIKTIEELDFVL
                     SFEGINTVAVELVFQDLENPIISKKVIDDLHEKGLLIWVNALTLSDSIILSAKIDDDT
                     AIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLV"
BASE COUNT          313 a          105 c          150 g          270 t
ORIGIN      
        1 acttatccat tgacacgttc caagaaatcg gatacaatgt aattaacaat aaagatagga
       61 gaaaataatt tgaatccatt aaaagaatgc tatgaaaaaa acggtatact aattgcagca
      121 caccgtggta caaacggagg aaatatatta caaaacacat caaaagccta tttgaattcc
      181 atacgccata acgcagatat gtttgaggtt gatgtaattc gttcaaaaga tggagaattt
      241 tttgcatttc acgatgggca agaaccttta gtatttggtg aaaaaattga tattagaact
      301 ttgagttctg aagagatcca aagaaaggaa tgttttaatt cactgaatga acccatatta
      361 caaaagattg aaaaaatttc tgatgtatta aaaaattttg agggacagtc tttaataaat
      421 atagatagaa gttggtttta ctgggatacc ttcctataaa atcacctgta aaaaaagaat
      481 tattggaaat gcttagagac tctggtttga atgttatgta tatgccaatt atcaaaacaa
      541 ttgaagagtt agattttgtt ctttcatttg aaggaataaa tacagtagct gtcgaacttg
      601 tattccaaga tttagaaaat ccaatcataa gtaagaaagt aattgatgat ttacatgaaa
      661 aaggattact tatttgggtt aatgctttaa ccttaagtga ttcaattatt ctttcggcta
      721 agattgatga tgatacagct attgctcatg atggcgaatc ttgggggaaa ttggtttcaa
      781 taggatttga tattattcaa acagattggc cattattact ttatcaatat ctagttga
//
LOCUS       DAVKBC010000104          731 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVKBC010000104 DAVKBC010000000
VERSION     DAVKBC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.104"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            251..469
                     /locus_tag="VWX64_002022"
     CDS             251..469
                     /locus_tag="VWX64_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9191413.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
BASE COUNT          320 a           80 c          127 g          204 t
ORIGIN      
        1 tgtgatgaaa atttaatatg taaatctcag acgatagaaa ttaaaaactc tatcgtcttt
       61 tttatactca aaattaggag gtaaaaatgg taaggataag aggtcccact taaaacaatt
      121 tatggcaaaa taaggacgga ataacacaac aaattctcta aaacaaatca ctaaatcaat
      181 gtaagattga atgaaatcaa tatttatgct ataattaaat aaatttaatg aagaaaaaaa
      241 gagggatatt atggcactta actataaacc attatggata cagttagcaa aaaaaggact
      301 aaagaaaaca gatgtaatag ctatggcagg acttacaaca aatgttatgg cacaaatggg
      361 aaaggataaa ccaattacat ttaagaattt agaaagaata tgtaaggctt tatcttgcac
      421 tcctaatgat attattagtt ttgaagataa ttttagtgac gaggaataga aaatgacttt
      481 aaggacagaa gatcaagtta gggattatgc aagagaagta taggctttaa tgaagttgaa
      541 gaaaacatca atcaaggtac tggtcaaata actactttta atcaattagg cttcaaggga
      601 tattcagata agccagatgg ttggtattta cctaaaaata tgaatgatgt agcaataatc
      661 cttgaaacaa aatcagaaga aagagatatt agcaaacaaa tttttattga tgagttaatg
      721 aaaaatatag a
//
LOCUS       DAVKBC010000105          647 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVKBC010000105 DAVKBC010000000
VERSION     DAVKBC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..647
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.105"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..176)
                     /locus_tag="VWX64_002023"
     CDS             complement(<1..176)
                     /locus_tag="VWX64_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9191414.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELLSNINVSI"
     gene            complement(189..>647)
                     /locus_tag="VWX64_002024"
     CDS             complement(189..>647)
                     /locus_tag="VWX64_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9191415.1"
                     /translation="SFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATF
                     GENGVVNYLASLFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDD
                     LVKYIQSFKGISEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
BASE COUNT          223 a          124 c           71 g          229 t
ORIGIN      
        1 tctatcgaaa cattgatatt tgataataat tcaaaaaatg ttgaaagaga aatttcattt
       61 tctccccttt caaatctaga aagttgagat tttgatataa aatcagctgc agcatactct
      121 aaagaatatc cgtttaattt tctaaaatat cgaaaagctt ctccgtaatt tttcacactt
      181 tcattccctt aactttcttt tcgagcgata aacataccat attctttagg aatgatcaac
      241 ataccattat taaactcact ttccaatctt ttacgtatta tttcctcttc tagtgaacct
      301 atttctgaaa ttcctttaaa cgattggatg tatttaacta ggtcatctat actagttacc
      361 tgtaactcat catcatagag taatgtatcg acagagttaa aatacctact caggtacctt
      421 ttaccatttt gtaaagtaaa cgttctattt tctaaatctt gattaacctc atctttaaat
      481 aaacttgcca aataatttac aactccattt tcaccaaatg tagcacagta aaaaatgcct
      541 ccggttttta agaccctatt cacctcagag agagctttag gaatatcatt cacatgatgt
      601 agaagcatat tagcaataac aatatcaaaa gtttcattct caaaaga
//
LOCUS       DAVKBC010000106          623 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVKBC010000106 DAVKBC010000000
VERSION     DAVKBC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.106"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..>623
                     /gene="phtB"
                     /locus_tag="VWX64_002025"
     CDS             <1..>623
                     /gene="phtB"
                     /locus_tag="VWX64_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU9191416.1"
                     /translation="PIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDS
                     KLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKGRQVDFEALDNLL
                     ERLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDG
                     YIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEK"
BASE COUNT          204 a          114 c          144 g          161 t
ORIGIN      
        1 tccaattgat gagaaattgg tcaaagaagc tgttcgaaaa gtaggcgatg gttatgtctt
       61 tgaggagaat ggagtttctc gttatatccc agccaaggat ctttcagcag aaacagcagc
      121 aggcattgat agcaaactgg ccaagcagga aagtttatct cataagctag gagctaagaa
      181 aactgacctc ccatctagtg atcgagaatt ttacaataag gcttatgact tactagcaag
      241 aattcaccaa gatttacttg ataataaagg tcgacaagtt gattttgagg ctttggataa
      301 cctgttggaa cgactcaagg atgtctcaag tgataaagtc aagttagtgg atgatattct
      361 tgccttctta gctccgattc gtcatccaga acgtttagga aaaccaaatg cgcaaattac
      421 ctacactgat gatgagattc aagtagccaa gttggcaggc aagtacacaa cagaagacgg
      481 ttatatcttt gatcctcgtg atataaccag tgatgagggg gatgcctatg taactccaca
      541 tatgacccat agccactgga ttaaaaaaga tagtttgtct gaagctgaga gagcggcagc
      601 ccaggcttat gctaaagaga aag
//
LOCUS       DAVKBC010000107          550 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVKBC010000107 DAVKBC010000000
VERSION     DAVKBC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.107"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            87..158
                     /locus_tag="VWX64_002026"
     tRNA            87..158
                     /locus_tag="VWX64_002026"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:120..122,aa:Glu,seq:ttc)
     gene            412..>550
                     /locus_tag="VWX64_002027"
     rRNA            412..>550
                     /locus_tag="VWX64_002027"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          201 a           86 c          136 g          127 t
ORIGIN      
        1 tgcaaaaaaa atgaaaaaaa ttagaaaaag tagttgacaa agtttgaaaa gactgtataa
       61 tagtaagagt tgaaaataac aactcaggtc cgttggtcaa ggggttaaga caccgccttt
      121 tcacggcggt aacacgggtt cgaatcccgt acggactatg gtatgttgcg gttggaacac
      181 ttgatgaaaa aaagtttaaa aaagcttaaa aatcttcaaa aaaagtgttg acaagtgaaa
      241 gtggctgtga tatactaata tagttgtcgc ttgagagaag caagtgacaa agacctttga
      301 aaactgaaca agacgaacca atgtgcaggg cgctacaaca taagttgtag tactgaacaa
      361 tgaaaaaaac aataaatctg tcagtgacag aaatgagtaa gaactcaaac ttttaatgag
      421 agtttgatcc tggctcagga cgaacgctgg cggcgtgcct aatacatgca agtagaacgc
      481 tgaaggagga gcttgcttct ctggatgagt tgcgaacggg tgagtaacgc gtaggtaacc
      541 tgcctggtag
//
LOCUS       DAVKBC010000108          529 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVKBC010000108 DAVKBC010000000
VERSION     DAVKBC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.108"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..418
                     /locus_tag="VWX64_002028"
     CDS             <1..418
                     /locus_tag="VWX64_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU9191417.1"
                     /translation="KNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT          204 a           82 c          107 g          136 t
ORIGIN      
        1 taaaaataag gcagaccaag atagtaaacc tgatgaagat aagggacatg atgaagtaag
       61 tgagccaact caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc
      121 agataatctt tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac
      181 tacagatgag gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga
      241 tgcggaggcc ttgctagaaa aagtaacaga tcctagtatt agacaaaatg ctatggagac
      301 attgactggt ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc
      361 agaagtagat agtctcttgg ctttgttaaa aaaaagtcaa ccggctccga tacagtagta
      421 aaatgaatgg agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa
      481 aaatgtaaca gaaacttgac aaaagtaatt ttaaatagta aactattta
//
LOCUS       DAVKBC010000109          469 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVKBC010000109 DAVKBC010000000
VERSION     DAVKBC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.109"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..225
                     /locus_tag="VWX64_002029"
                     /pseudo
     CDS             1..225
                     /locus_tag="VWX64_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
BASE COUNT          161 a           73 c           86 g          149 t
ORIGIN      
        1 gatcgagttg aattttatgg ttcaggtttc cgtcattttg aaacctatat tgaagatttg
       61 catgatgcca aaggcaataa aatcgaccgc gctccaaatc caatggaact attgactatt
      121 aaagtcccat aacctgttca atcaggagac atggttcgtg cattaaaaga aggactcatc
      181 aatctttata aggaagatgg aaccagcgtc acagttcgtg cttaatgtag ttgtttagtt
      241 ttaaaaaatt atgcaaagct ccatatacaa cacttaaacg agattaaaga atggcgaaat
      301 cccttgatgc gcaagagatt agctgtcctt ttttattttt taagtgataa agtcggagct
      361 taggtatcaa agcctatcaa attaaacaaa gaagcgatgt cttagatatt ttgaaaaaaa
      421 ttaataagca aaaaactctc tattattttg ttgtagagag ttttttgtt
//
LOCUS       DAVKBC010000110          410 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVKBC010000110 DAVKBC010000000
VERSION     DAVKBC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.110"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..>410
                     /locus_tag="VWX64_002030"
     CDS             <1..>410
                     /locus_tag="VWX64_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9191418.1"
                     /translation="FGKERKSLQGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEG
                     RMKSIHYVSTVTNCYKAAVDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPS
                     ENEQLFGARRKIPEYKFVAEVVSYDDAAQTATIR"
BASE COUNT          124 a           74 c          101 g          111 t
ORIGIN      
        1 tttgggaaag aacgtaagag tttgcagggt gagattccag aagaattttc aatgtcagcc
       61 gttgacatgt ctatgattga ccacattcca gatatgattg aaaatggtgt ggacagtcta
      121 aaaatcgaag gacgtatgaa gtctattcac tacgtatcaa cagtaaccaa ctgctacaag
      181 gcggctgtgg atgcctatct tgaaagtcct gaaaagtttg aagctatcaa acaagacttg
      241 gtggacgaga tgtggaaggt tgcccaacgt gaactggcta caggatttta ctatggtaca
      301 ccatctgaaa atgagcagtt gtttggtgct cgccgtaaaa ttcctgagta caagtttgtc
      361 gctgaagtgg tttcttatga tgatgcggca caaacagcaa ccattcgtca
//
LOCUS       DAVKBC010000111          396 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00064161
            SAMN33606264-rid17939853.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVKBC010000111 DAVKBC010000000
VERSION     DAVKBC010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606264
            Sequence Read Archive: SRR23727643
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722685.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722685.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:29:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,031
            CDSs (total)                      :: 1,980
            Genes (coding)                    :: 1,840
            CDSs (with protein)               :: 1,840
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 140
            CDSs (without protein)            :: 140
            Pseudo Genes (ambiguous residues) :: 0 of 140
            Pseudo Genes (frameshifted)       :: 70 of 140
            Pseudo Genes (incomplete)         :: 61 of 140
            Pseudo Genes (internal stop)      :: 41 of 140
            Pseudo Genes (multiple problems)  :: 29 of 140
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606264-rid17939853.denovo.111"
                     /strain="AUSMDU00064161"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..396
                     /locus_tag="VWX64_002031"
                     /pseudo
     CDS             1..396
                     /locus_tag="VWX64_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          131 a           80 c           84 g          101 t
ORIGIN      
        1 ggttaacgtg ggaatttcaa ccatttacta ttggattcat catggaaaat tggggtaaag
       61 caagcaggat ctgctttacc ctagaaaagg aaaagcgctt aagaaacagg ccagcaccaa
      121 ctttaaacct gctggtcaat ccatcgaaca gcggcctgaa gctatcaatt ttcgcttgga
      181 gaatgggcat tatgagattg atacggttct acttacgaga gcgaaaaact actgcttgct
      241 tgtcttgacg gatcgaaaaa gtagacatca gatcatccga ttgattccaa ataaaagtgc
      301 tgaggtggtc aatcaggctc taaaactcat cttaaaacaa cacaagattc tttccatcac
      361 ggcagataat ggaacggaat tcaatcgctt gtctaa
//
